ライフサイエンスコーパス: transduction pathway

1 ese genes to investigate the c-di-GMP signal transduction pathway.

2 es harboring components of the visual signal transduction pathway.

3 ggesting early activation of the STAT signal transduction pathway.

4 ing those involved in the phytochrome signal transduction pathway.

5 in cell proliferation through the Shh signal transduction pathway.

6 nase/mitogen-activated protein kinase signal transduction pathway.

7 ellular signal-regulated kinase (ERK) signal transduction pathway.

8 receptor-like 1 (IL1RL1), act in one signal transduction pathway.

9 it is an indispensable part of the OS signal transduction pathway.

10 ough a hitherto unknown communication signal transduction pathway.

11 ption is mediated through cAMP/PKA signaling transduction pathway.

12 rotein kinase A signaling is involved in the transduction pathway.

13 al transporter that acts as a processor in a transduction pathway.

14 unoreceptor tyrosine-based activation signal transduction pathway.

15 nflammation or activation of the STAT signal transduction pathway.

16 volutionarily conserved regulators of signal transduction pathways.

17 asured responses of a few proteins or signal transduction pathways.

18 or conformations activating different signal transduction pathways.

19 adation, subcellular localization and signal transduction pathways.

20 vous system functions through diverse signal transduction pathways.

21 ule frequency in reaction to internal signal transduction pathways.

22 Gsk-3) is a key regulator of multiple signal transduction pathways.

23 o cancer treatment focus on targeting signal transduction pathways.

24 cellular regulation of immune system signal transduction pathways.

25 the critical steps for many cellular signal transduction pathways.

26 r outputs and responses by modulating signal transduction pathways.

27 xert reversible control over numerous signal transduction pathways.

28 aling factors involved in many intracellular transduction pathways.

29 esis 8 (DOCK8), which are involved in signal transduction pathways.

30 s, and is often activated by multiple signal transduction pathways.

31 nuated signaling through the STAT3 and c-Src transduction pathways.

32 act indirectly via receptor-mediated signal transduction pathways.

33 d carcinoma and describe the involved signal transduction pathways.

34 re not simply downstream executors of signal transduction pathways.

35 interactions that stimulate numerous signal transduction pathways.

36 trafficking, and the organization of signal transduction pathways.

37 on that is necessary in understanding signal transduction pathways.

38 ed to selectively modulate downstream signal transduction pathways.

39 s as a mediator of cross-talk between signal transduction pathways.

40 l decision-making in association with signal-transduction pathways.

41 ow activation of yet to be identified signal transduction pathways.

42 of cytokine receptors or TLR-mediated signal transduction pathways.

43 lly important phosphatases feature in signal transduction pathways.

44 ymatic complexes to the regulation of signal transduction pathways.

45 timuli and initiate specific cellular signal transduction pathways.

46 approach was implemented to block adenovirus transduction pathways.

47 ing the general principles underlying signal transduction pathways.

48 cell-surface proteins and controlling signal transduction pathways.

49 ls to the activation of intracellular signal transduction pathways.

50 cytokine production and activation of signal transduction pathways.

51 effects of 4-OH-E2 on redox-sensitive signal transduction pathways.

52 gnal-regulated protein kinases (ERKs) signal transduction pathways.

53 chemotaxis is one of the best studied signal transduction pathways.

54 the cytosol is a hallmark of key signalling transduction pathways.

55 e require a coordinated regulation of signal transduction pathways.

56 olves a complex interplay between key signal transduction pathways.

57 nvolving TLR4/MyD88 and NFkappaB/MAPK signal transduction pathways.

58 Epr3 is integrated into the symbiosis signal transduction pathways.

59 teins into complexes, organelles, and signal transduction pathways.

60 a cells and for the study of involved signal transduction pathways.

61 ell transformation and the associated signal transduction pathways.

62 were used to determine activation of signal transduction pathways.

63 nsory physiology and modulate various signal transduction pathways.

64 ommunicate with their environment via signal transduction pathways.

65 n regulating protein stability and signaling transduction pathways.

66 biogenesis, and phosphorylation-based signal transduction pathways.

67 essenger that plays a central role in signal transduction pathways.

68 genes, and dysregulation of multiple signal-transduction pathways.

69 unction as an integrated two-receptor signal transduction pathway, a finding with implications for ra

70 Signal transduction pathways activated by chemoattractants have

71 also one of the major players in the signal transduction pathways activated in response to DNA damag

72 sponses depending upon the balance of signal transduction pathways activated, targeting specific VEGF

73 ecular composition, the intracellular signal transduction pathways, active during specific phases of

74 tion can be an important modulator of signal transduction pathways, akin to phosphorylation.

75 e, we observed that perturbation in estrogen transduction pathway altered MHC Class II, alpha-AChR, a

76 which binds to a crucial site in the agonist transduction pathway and causes conformational changes t

77 ance signaling molecules that control signal transduction pathways and are necessary for cellular hom

78 onal modification controlling several signal transduction pathways and displaying an acute effect on

79 L2 is a crucial modulator of multiple signal transduction pathways and functions as a scaffold in spe

80 L16 stimulation, but exhibited unique signal transduction pathways and homing properties.

81 tin cytoskeletal dynamics, regulating signal transduction pathways and inhibiting host secretory path

82 Ras GTPase mediates several cellular signal transduction pathways and is found mutated in a large nu

83 ing the action of ethylene through different transduction pathways and its interaction with other hor

84 concentrations, which disrupt normal signal transduction pathways and lead to an overactivation of m

85 heir host genes involved in olfactory signal transduction pathways and other critical neurological pr

86 G-protein-coupled receptors regulate signal transduction pathways and play diverse and pivotal roles

87 kinase 1/2, and ribosomal S6 kinase 1 signal transduction pathways and subsequent increase in cAMP re

88 ole of the ERM proteins in regulating signal transduction pathways and suggests that modulation of mo

89 od with our evolved knowledge of many signal transduction pathways and the way they converge and regu

90 itecture to integrate the activity of signal transduction pathways and transcriptional regulators, an

91 sed different, functionally unrelated signal transduction pathways and were expressed in different re

92 t responses, it should act through different transduction pathways and/or in conjunction with other s

93 hoinositide 3-kinase/protein kinase B signal transduction pathway, and that can be overcome by miR-7

94 ll cycle control, microRNA silencing, signal transduction pathways, and hormone-driven disease.

95 derived from the interaction with important transduction pathways, and many of its effects are consi

96 are tightly controlled by enzymes and signal transduction pathways, and their dysregulation leads to

97 cross-talk among the external milieu, signal transduction pathways, and transcription factors that di

98 -IL-1beta, generally via NF-kappaB-dependent transduction pathways; and the assembly and activation o

99 e also signalling molecules whose respective transduction pathways are being intensively studied.

100 itochondrial oxidative metabolism and energy transduction pathways are critical for skeletal and card

101 ms biology approaches to defining how signal transduction pathways are integrated at the level of who

102 Host cell signal transduction pathways are often targets of bacterial pat

103 different pathologies, but its intracellular transduction pathways are still largely unknown.

104 tes in the canonical Wnt/beta-catenin signal transduction pathway as well as modulating cytoskeleton

105 Increasing knowledge about signal transduction pathways as drivers of cancer growth has el

106 enerating a holistic view of cellular signal transduction pathways as exemplified by analysis of bort

107 the feedback regulation of olfactory signal transduction pathways as well as the control of subcellu

108 udy are the first to define the LytSR signal transduction pathway, as well as determine the metabolic

109 ligand-specific activation of certain signal transduction pathways at a receptor that can signal thro

110 ed a crosstalk between the TLR4 and beta2-AR transduction pathways at the NF-kappaB level.

111 nner and therefore fills a gap in the signal transduction pathway between pathogen recognition and SA

112 ia FGF receptor 4 (Fgfr4), mediates a signal-transduction pathway between Wnt16 and Dlc, but not Dld,

113 tune the activation of intracellular signal transduction pathways both predictably and selectively w

114 s are controlled by a small number of signal-transduction pathways, but how the specificity of functi

115 hylation is an important modulator of signal transduction pathways, but methyltransferases themselves

116 p-regulation is not driven by hormone-driven transduction pathways, but rather is associated with red

117 ow binding and activation of Dectin-1 signal transduction pathway by the beta-glucan-containing vacci

118 Diversion of the force transduction pathway by the introduction of appropriatel

119 pressed only in males, as well as the signal transduction pathway by which episodic GH solely regulat

120 ors, and some family members modulate signal transduction pathways by acting as co-receptors.

121 The activation of cellular signal transduction pathways by solar ultraviolet (SUV) irradia

122 in part, through redox-sensitive AKT signal transduction pathways by up-regulating the expression of

123 However, the signal transduction pathways by which extracellular signals reg

124 In budding yeast, one such signal transduction pathway called the mitotic exit network (ME

125 Changes in these signal transduction pathways can lead to differential gene regu

126 stresses are often very specific, but signal transduction pathways can partially or completely overla

127 d membrane-trafficking intermediates, signal transduction pathways, cell cycle regulators, the organe

128 mtDNA may emerge from studies of how signal transduction pathways command mitochondrial function.

129 h is controlled through a proteolytic signal transduction pathway comprising a sensor protein (MecR1)

130 haracterise a multi-step phosphorelay signal transduction pathway consisting of TcsA, TcrA, FsrR, Rpo

131 the phosphoinositide 3-kinase (PI3K) signal transduction pathway contribute to the hypothalamic regu

132 Multiple wound-related signal transduction pathways control the deposition of EDA FN,

133 ellular stress response; however, the signal transduction pathways controlling autophagy induction in

134 Ras is at the hub of signal transduction pathways controlling cell proliferation and

135 Signal transduction pathways converge upon sequence-specific DN

136 icating that targeting a specific D2R signal transduction pathway could allow for more precise modula

137 profiles of genes enriched in several signal transduction pathways critical for coronary heart diseas

138 o and regulates synaptic adhesion and signal transduction pathways critical for normal cognition and

139 However, the signal transduction pathways culminating in the biological cons

140 ation of several processes, including signal transduction pathways, development, and disease.

141 Suppressing FGFR or its downstream signal transduction pathways diminished Lgr5-expressing cells i

142 ults suggest that CnrN functions in a signal transduction pathway downstream of AprA and CfaD mediati

143 skeletal protein networks and complex signal transduction pathways driven by localized proteins.

144 g pathway is considered to be a major signal transduction pathway during embryonic development, but i

145 in vivo the requirement of different signal transduction pathways emanating from KIT for tumorigenes

146 Activation of the EphR-Ephrin signal transduction pathway enhances S863 phosphorylation.

147 ction as modulators of a multitude of signal transduction pathways evoked by environmental stimuli.

148 en proposed to play a central role in signal transduction pathways evoked by the drought and stress h

149 PhoB and TctD mediated two-component signal transduction pathways exemplify how P. aeruginosa may ex

150 s or complement, suggesting that alternative transduction pathways exist.

151 rough direct interactions with ILK, a signal transduction pathway firmly linked to cell motility and

152 s as a key control element in the allosteric transduction pathway for potentiating betaEST and dFBr.

153 The signal transduction pathways for the cross talk between the rem

154 NPM-ALK co-opts several intracellular signal transduction pathways, foremost being the STAT3 pathway,

155 Notch signaling is a ubiquitous signal transduction pathway found in most if not all metazoan c

156 with sphingolipid metabolism and link signal transduction pathways from the plasma membrane to the re

157 This result allowed us to elucidate transduction pathways from twin drug-binding cavities to

158 The evolutionary conserved Wnt signal transduction pathway has long been known for its importa

159 Disruption of such metabolic transduction pathways has severe consequences for the en

160 ugh central elements in the cytokinin signal transduction pathway have been identified, mechanisms co

161 Light signal transduction pathways have been extensively studied in p

162 r mechanisms that underlie plant cell signal transduction pathways have successfully used the yeast t

163 d crucial pathways, including several signal transduction pathways, hormone response, oxidative respo

164 ordered proteins are instrumental for signal-transduction pathways; however, many mechanistic aspects

165 evidence for a novel target gene and signal transduction pathway in adipocytes and indicates that in

166 signaling regulation, a two-component signal transduction pathway in bacterial homeostasis, and a sig

167 environment, activating the NF-kappaB signal transduction pathway in MDSCs and regulating their quant

168 Our data describe a novel signal transduction pathway in neurons whereby ApoE activates a

169 BMP receptors and members of the SMAD signal transduction pathway in nociceptive sensitization was al

170 dopsis thaliana forward nuclear auxin signal transduction pathway in Saccharomyces cerevisiae to test

171 RECEPTOR KINASE1 (BAK1) to initiate a signal transduction pathway in which autophosphorylation and tr

172 acterial phosphotransferase system, a signal transduction pathway in which phosphoryl transfer throug

173 re involved in multiple signaling and signal transduction pathways in a wide variety of cellular and

174 roenvironment, epithelial plasticity, signal transduction pathways in cancer progression, and disease

175 tein kinases regulate the majority of signal transduction pathways in cells and have become important

176 separate, but overlapping, mechanoelectrical transduction pathways in chondrocytes.

177 The crosstalk between these signal transduction pathways in coordinating environmental cues

178 Epigenetic enzymes modulate signal transduction pathways in different biological contexts.

179 sive, validated, and annotated map of signal transduction pathways in inflammatory Mvarphis based on

180 Calcium is a second messenger in signal transduction pathways in plants, and it has been indirec

181 CrkL are capable of initiating major signal transduction pathways in response to extracellular stimu

182 screening-type analysis of potential signal transduction pathways in the cells.

183 d as tools for selectively modulating signal transduction pathways in vitro and in vivo.

184 Emerging work points to Nrf2-Keap1 signal transduction pathway inhibitors, including Bach1 and c-M

185 G proteins play a pivotal role in the signal-transduction pathways initiated by G-protein-coupled rec

186 confirms the pan-cancer importance of signal transduction pathways, innate and adaptive immune signal

187 These results indicate that a signal transduction pathway involved in self-renewal and surviv

188 However, little is known about the signal transduction pathways involved in mechanical stimuli res

189 However, signal transduction pathways involved remain largely unidentifi

190 Traditional study of signal transduction pathways involves mapping cellular signalin

191 These data define a novel signal transduction pathway involving c-src that is activated b

192 s is reported that operates through a signal transduction pathway involving multivalent interactions.

193 Our studies have identified a signal transduction pathway involving ROS, PKC, ERK, and p38 MA

194 ar remodeling is mediated by specific signal transduction pathways involving NFAT or C/EBPbeta transc

195 controlled by multiple interconnected signal transduction pathways involving reversible phosphorylati

196 tion is not mediated by the canonical signal transduction pathway, involving ApoER2/VLDLR and Dab1, t

197 BR signal transduction pathway is well elucidated in Arabidopsis b

198 ness of cancer therapeutics targeting signal transduction pathways is comprised of a diversity of mec

199 ally signal through a small number of signal transduction pathways is not well resolved.

200 lysis reveals that the 'plant hormone signal transduction' pathway is enhanced during pollen-pistil i

201 homologous yet distinct components of signal transduction pathways known to regulate cell survival an

202 a number of key elements in cellular signal transduction pathways linked to apoptosis, angiogenesis,

203 Understanding the mechanism of the signal transduction pathways mediated by these proteins may off

204 t, we examined whether Pfs47 affected signal transduction pathways mediating mosquito immune response

205 To address the signal transduction pathways mis-regulated in renal injury, we

206 endowed with a PLCbeta2/IP3 R3/TRPC6 signal transduction pathway modulating release of neuropeptide

207 between HIV-1 proteins and key human signal transduction pathways necessary for activation of CD4+ T

208 as the upstream components of growth signal transduction pathway of psoriatic pathogenesis.

209 The signal transduction pathway of the DNA damage response (DDR) is

210 ver, the underlying intracellular signalling transduction pathways of alpha-syn-mediated mDA neurodeg

211 ssed systemic insulin sensitivity and signal transduction pathways of glucose utilization at the mRNA

212 n of IL-21 contributes to the overall signal transduction pathways of the Ag receptor to influence th

213 Thus, two signal transduction pathways, one depending on PI3K, another on

214 c events converging on the same gene, signal transduction pathway, or protein complex in different su

215 The signal transduction pathways, orchestrating the differentiation

216 sed following stimulation by multiple signal transduction pathways, our findings also suggest that ce

217 a2+/CaM as a limiting resource in the signal transduction pathway owing to its low abundance relative

218 scription factor of the abscisic acid signal transduction pathway, plays a major role during seed dev

219 The signal transduction pathways present during the early phases of

220 phosphodiesterase 1C, fundamental olfactory transduction pathway proteins.

221 echanisms on the dynamics of parallel signal transduction pathways; reciprocal side-effects between s

222 ure, constitutive activity, isoforms, signal transduction pathways, regional differences in expressio

223 Signal-transduction pathways regulated by extracellular signals

224 iculum stress and modulating multiple signal transduction pathways regulating cancer cell growth, inv

225 To screen for signal transduction pathways regulating mRNA export complex ass

226 anisms that negatively regulate these signal transduction pathways remain poorly understood.

227 In this study, we investigated the signal transduction pathways responsible for APOBEC3B upregulat

228 herefore investigated the signals and signal transduction pathways resulting in ACSL1 induction in ma

229 Little is known about the signal transduction pathway(s) controlling PhyR phosphorylation

230 Investigating the YopH-targeted signal transduction pathway(s) in neutrophils during infection

231 Yet, the signal transduction pathway(s) seems to be noncanonical, indepe

232 This highlights the existence of signal transduction pathway(s) that limit plant development und

233 ub-zero acclimation, although the CBF signal transduction pathway seems to be less important during s

234 , and survival; activation of the key signal transduction pathways STAT3 and mTORC1; and expression o

235 ion 3 (STAT3), while preserving other signal transduction pathways such as Akt and extracellular sign

236 rnalization and activation of several signal transduction pathways, such as phosphoinositide 3-kinase

237 ) terms associated with signaling and signal transduction pathways, suggesting the presence of conser

238 We also found signal transduction pathways tend to show extensive dynamic rel

239 tropes, we investigated the potential signal transduction pathway that conveys the inhibitory action

240 unfolded protein response (UPR) is a signal transduction pathway that coordinates cellular adaptatio

241 P kinase signaling cascade, a central signal transduction pathway that governs a broad spectrum of bi

242 cts both like a component of the FGF4 signal transduction pathway that governs trophoblast proliferat

243 jor pathway is the canonical ethylene signal transduction pathway that incorporates CONSTITUTIVE TRIP

244 naling is an evolutionarily conserved signal transduction pathway that is essential for metazoan deve

245 of the alpha7 nAChR is mediated by a signal transduction pathway that is independent of ion current.

246 part of an operon encoding the VieSAB signal transduction pathway that is nearly silent in V. cholera

247 tic synaptic plasticity; however, the signal transduction pathway that links reduced Ca(2+)-levels to

248 H2O2 signaling is under control of a signal transduction pathway that links the respiratory chain to

249 operate downstream of cytokinins in a signal transduction pathway that negatively regulates plant pri

250 ons suggest that metformin inhibits a signal transduction pathway that results in an inflammatory res

251 odification (PTM) is a key feature of signal-transduction pathways that allows the modulation of prot

252 gent that invokes the blockage of two signal transduction pathways that are central to the developmen

253 apable of activating several cellular signal transduction pathways that are ICP27 dependent.

254 ling, which may begin to identify the signal transduction pathways that are important in the physiolo

255 activated the PI3K.Akt and Wnt.beta-catenin transduction pathways that are known to be involved in t

256 toxin-induced death by stimulation of signal transduction pathways that are linked to prion protein.

257 re poorly understood, but may include signal transduction pathways that are modulated by changes in i

258 Signal transduction pathways that are regulated by pH and Ca(2+

259 ncer is to understand the cellular signaling transduction pathways that cause cancer at the level of

260 Thus, amino acids could activate signal transduction pathways that control cell metabolism.

261 mented IHVR, is regulated by multiple signal transduction pathways that could be potential therapeuti

262 te to TAV by initiating outside-in signaling transduction pathways that elicit monocyte recruitment t

263 ery from pneumonia, and modulation of signal transduction pathways that have been linked to prion pro

264 activated through complex and cross-talking transduction pathways that include a mitogen-activated p

265 VEGF-A stimulates signal transduction pathways that modulate endothelial outputs

266 er decades of basic research into the signal transduction pathways that promote cancer cell survival,

267 Restraint of intracellular signal transduction pathways that promote release of mast cell-

268 sphorylation, which in turn activates signal transduction pathways that regulate cell-collagen intera

269 atively little is known regarding key signal transduction pathways that serve as cytosolic bridges be

270 giomotin triggered the activation of several transduction pathways that were identified by antibody a

271 One component of the BAG transduction pathway, the receptor-type guanylate cyclas

272 n extension of the established immune signal transduction pathways, thereby adding an extra layer of

273 However, the signal transduction pathways through which mGluR5s regulate coc

274 CWI mitogen-activated protein kinase signal transduction pathway to target the relocalization and co

275 eptors (GPCRs) utilize (at least) two signal transduction pathways to elicit cellular responses inclu

276 ity is that information is encoded in signal transduction pathways to ensure stimulus- and cell type-

277 , ranging from epigenetic control and signal transduction pathways to global and specific transcripti

278 cts as a docking platform integrating signal transduction pathways to nucleic acid-related processes.

279 4, thereby integrating phase-specific signal transduction pathways to regulate cell cycle progression

280 Bacteria frequently use two-component signal transduction pathways to sense and respond to environmen

281 ocytic beta1 integrins, which trigger signal transduction pathways toward choleresis.

282 y of proteins to fulfill key roles in signal transduction pathways triggered by activation of recepto

283 etabolite sphingosine 1-phosphate, on signal transduction pathways under cell stress is important to

284 by toll-like receptor 4 (TLR-4)/MyD88 signal-transduction pathway up-regulation of MLCK expression.

285 meability was mediated by TLR-4/MyD88 signal-transduction pathway up-regulation of MLCK.

286 This mechanism might be a general signal transduction pathway used by PP2A to initiate cell cycle

287 S1P1 directly activated the Jak-STAT3 signal-transduction pathway via IL-6.

288 esults indicated that the p38-related signal transduction pathway was dramatically affected by SUV ir

289 The olfactory transduction pathway was the most enriched pathways for

290 Signal transduction pathways were characterized in Ba/F3 cells

291 , loci expressing other regulators of signal transduction pathways were conspicuous among the common

292 Targeting signal transduction pathways which promote therapy resistance a

293 nsduced by a receptor kinase-mediated signal transduction pathway, which is distinct from animal ster

294 en lead to dysregulation of oncogenic signal transduction pathways, which in turn alters downstream t

295 NFkappaB and MAPKs were used to study signal transduction pathways while TLR4 and MyD88 were silenced

296 a protein known to integrate multiple signal transduction pathways with gene expression, as a SERT di

297 ght stress depend on highly regulated signal transduction pathways with multiple interactions.

298 for treating the disease by modifying signal transduction pathways with small-molecule drugs.

299 n the exterior of a cell and activate signal transduction pathways within the cell.

300 central energy/stress sensing kinase signal transduction pathways within the nucleus.