ライフサイエンスコーパス: transfer RNA

1 te and releasing the peptide from the P-site transfer RNA.

2 separated 30S and 50S subunits and initiator transfer RNA.

3 ate, resulting in a P/E hybrid state for the transfer RNA.

4 ce complementary to the 3' end of a cellular transfer RNA.

5 t attachment of amino acids to their cognate transfer RNA.

6 solely responsible for the aminoacylation of transfer RNA.

7 of the nascent protein chain from the P-site transfer RNA.

8 acid that is already attached to a "correct" transfer RNA.

9 g to a spring-like deformation of the P-site transfer RNA.

10 lation to specific locations in ribosomal or transfer RNA.

11 (U) to pseudouridine (Psi) at position 55 in transfer RNA.

12 function, plus three ribosomal RNAs, and 17 transfer RNAs.

13 dogenous 5'-phosphate-capped RNAs, including transfer RNAs.

14 DNA replication, chromosomal breakpoints and transfer RNAs.

15 ression of amino acid biosynthesis genes and transfer RNAs.

16 n synII, mainly caused by the deletion of 13 transfer RNAs.

17 g for 81 protein, four ribosomal RNAs and 29 transfer RNAs.

18 ze the specific pairings of amino acids with transfer RNAs.

19 erved proteins, three ribosomal RNAs, and 15 transfer RNAs.

20 t the role of specific base modifications of transfer RNAs.

21 uclease responsible for the 5'-maturation of transfer RNAs.

22 fic 2'-hydroxyl methylation of ribosomal and transfer RNAs.

23 alytic, ribosomal, small nuclear, micro, and transfer RNAs.

24 both and occupies the space normally used by transfer RNAs.

25 maturation of both nuclear and mitochondrial transfer RNAs.

26 evidence for the canonical functions of the transferred RNA.

27 perform simulations of large-scale aminoacyl-transfer RNA (aa-tRNA) rearrangements during accommodati

28 r Tu (EF-Tu) binds to all standard aminoacyl transfer RNAs (aa-tRNAs) and transports them to the ribo

29 We evolved a transfer RNA adenosine deaminase to operate on DNA when

30 nd other proteins in response to fluctuating transfer RNA aminoacylation levels under various nutriti

31 mportance of the 2'-hydroxyl of the peptidyl-transfer RNA and a Bronsted coefficient near zero have b

32 as the complex responsible for production of transfer RNA and a limited number of other small RNAs.

33 on of Met metabolism in mat3 pollen affected transfer RNA and histone methylation levels.

34 omprising a 40S ribosomal subunit, initiator transfer RNA and initiation factors (eIF) 2, 3, 1 and 1A

35 Ribosomal ribonucleic acid (RNA), transfer RNA and other biological or synthetic RNA polym

36 nt oxygenases that catalyse hydroxylation of transfer RNA and ribosomal proteins have been shown to b

37 in non-coding RNAs, enhances the function of transfer RNA and ribosomal RNA by stabilizing the RNA st

38 Ribosomes catalyze protein synthesis using transfer RNAs and auxiliary proteins.

39 y the ribosome requires the translocation of transfer RNAs and messenger RNA by one codon after each

40 or binding protein CTCF, housekeeping genes, transfer RNAs and short interspersed element (SINE) retr

41 that our two species had extremely truncated transfer RNAs and that gene overlaps occurred much more

42 We further find that SLFN11 binds transfer RNA, and counteracts changes in the tRNA pool e

43 HPF and YfiA overlap with those of the mRNA, transfer RNA, and initiation factors, which prevents tra

44 ation resulting from limiting ribosomal RNA, transfer RNA, and ribosomal protein mRNA.

45 process of bringing together mRNA, initiator transfer RNA, and the ribosome, is therefore of critical

46 sekeeping functions in cells-ribosomal RNAs, transfer RNAs, and small nucleolar RNAs.

47 Transfer RNAs are ancient molecules, perhaps even predat

48 Transfer RNAs are transcribed as precursors with extensi

49 ssential for the maturation of ribosomal and transfer RNA as well as the rapid degradation of messeng

50 We speculate that pools of transfer RNA available for protein translation impact on

51 e at this position is nearly invariate among transfer RNAs because of its role in stabilizing the ant

52 locations of eIF1, eIF1A, mRNA and initiator transfer RNA bound to the small ribosomal subunit and pr

53 c code are established by aminoacylations of transfer RNAs by aminoacyl tRNA synthetases.

54 proteins, Pnkp and Hen1, was able to repair transfer RNAs cleaved by ribotoxins in vitro.

55 Aminoacyl-transfer RNAs contain four standardized units: amino aci

56 es include an abundance of tandemly repeated transfer-RNA-containing arrays, which may have a structu

57 ome function (e.g., increased affinities for transfer RNAs, decreased rates of peptidyl-transfer), an

58 ation of the HIS2 transcription start due to transfer RNA deletion and loxPsym site insertion.

59 diet (HFD), we showed that a subset of sperm transfer RNA-derived small RNAs (tsRNAs), mainly from 5'

60 Transfer-RNA-derived small RNAs (tsRNAs; also called tRN

61 cent work indicates that many cells can also transfer RNA directly via cell-cell trafficking of nanom

62 ctedly, we found that codons decoded by rare transfer RNAs do not lead to slow translation under nutr

63 2-guanosine triphosphate-initiator methionyl transfer RNA (eIF2.GTP.Met-tRNA(i )(Met)).

64 ses (aaRS) join amino acids to their cognate transfer RNAs, establishing an essential coding relation

65 We present evidence that the entire set of transfer RNAs for all twenty amino acids are encoded in

66 Transfer RNA fragments (tRFs) are an established class o

67 We have created tRFdb, the first database of transfer RNA fragments (tRFs), available at http://genom

68 iculum (ER) stress through the production of transfer RNA fragments that interfere with translation i

69 A transfer RNA fusion engineered into domain II of the int

70 he pathogenic A3243T mutation in the leucine transfer RNA gene (tRNAleu)].

71 n RNA sequence in the chloroplast isoleucine transfer RNA gene (trnI.2) located in the rRNA operon.

72 The transfer RNA gene downstream from the HMR locus in S. ce

73 Transfer RNA genes are known to exhibit extra-transcript

74 s confirmed by 1,670 aligned transcripts, 19 transfer RNA genes, 341 pseudogenes and three RNA pseudo

75 y centromeres and include interactions among transfer RNA genes, among origins of early DNA replicati

76 protein coding genes, 2 ribosomal RNA and 22 transfer RNA genes, and a control region varying in size

77 nits), with each t-unit containing three pre-transfer RNA genes.

78 rotein-coding genes, 2 ribosomal RNAs and 22 transfer RNA genes.

79 -derived small RNAs (tsRNAs), mainly from 5' transfer RNA halves and ranging in size from 30 to 34 nu

80 f post-transcriptional base modifications in transfer RNAs have been described.

81 Human mitochondrial methionine transfer RNA (hmtRNA(Met)(CAU)) has a unique post-transc

82 uridine immediately 5' to the mitochondrial transfer RNA(Ile) anticodon.

83 igated metabolites such as aminoacyl-charged transfer RNA in the T-box system, or protein-bound metab

84 for the removal of introns from a subset of transfer RNAs in all eukaryotic organisms.

85 stop codon by utilizing switchable designer transfer RNAs in Escherichia coli .

86 neral control (GC) system, wherein uncharged transfer RNA induces phosphorylation of eukaryotic initi

87 iral subgenomic (SG), cellular messenger and transfer RNAs into released virions.

88 Transfer RNA is one of the most richly modified biologic

89 Selenocysteinyl transfer RNA knockout mice (Trsp(fl/fl)LysM(Cre)) were u

90 During protein synthesis, deacylated transfer RNAs leave the ribosome via an exit (E) site af

91 ed that cells use an elongator leucine-bound transfer RNA (Leu-tRNA) to initiate translation at crypt

92 After excision of the intron, transfer RNA ligase joins the severed exons, lifting the

93 on, similar to that found on viral RNAs with transfer RNA-like ends, may be essential for replication

94 e factors promote hydrolysis of the peptidyl-transfer RNA linkage in response to recognition of a sto

95 During ribosomal and transfer RNA maturation, external transcribed spacer (ET

96 all subunits of the ribosome, with initiator transfer RNA (Met-tRNA(i)(Met)) positioned over the star

97 First, methionylated initiator methionine transfer RNA (Met-tRNAi(Met)), eukaryotic initiation fac

98 rity to the anticodon of methionyl initiator transfer RNA (Met-tRNAi).

99 nticodon loop in the mitochondrially encoded transfer RNA methionine (mt-tRNA(Met)).

100 ons within the reaction centre of a peptidyl-transfer RNA mimic.

101 nsible for deoxyribonucleoside synthesis and transfer RNA modification appear to be crucial, as no al

102 M), its biosynthetic pathway and its role in transfer RNA modification.

103 Transfer RNA modifications play pivotal roles in protein

104 Here, using the transfer RNA molecule as a structural building block, we

105 ription, retroviruses require annealing of a transfer RNA molecule to the U5 primer binding site (U5-

106 The transfer RNA molecule translocates from the peptidyl sit

107 Translocation of messenger and transfer RNA (mRNA and tRNA) through the ribosome is a c

108 ate the various steps of translation such as transfer RNA-mRNA movement.

109 philus 70S ribosome along with the initiator transfer RNA N-formyl-methionyl-tRNA(i) (fMet-tRNA(i)(fM

110 Transfer RNA nucleotidyltransferases (CCA-adding enzymes

111 ylguanosine and N(2)(2)-dimethylguanosine in transfer RNA occur at five positions in the D and antico

112 s, three putative open reading frames and 33 transfer RNAs of 19 amino acids for peptide synthesis.

113 d light on the movement of messenger RNA and transfer RNA on the ribosome after each peptide bond is

114 d be required to ensure functional impact of transferred RNA on brain recipient cells and predict the

115 viruses, which evolved a capping enzyme that transfers RNA onto GDP, rather than GMP onto the 5' end

116 During translation, the primary substrates, transfer RNAs, pass through binding sites formed between

117 C5 is the protein subunit of the transfer RNA processing ribonucleoprotein enzyme RNase P

118 code is established by the aminoacylation of transfer RNA, reactions in which each amino acid is link

119 relate with an increased content of glutamyl-transfer RNA reductase.

120 old ntrc seedlings, the contents of glutamyl-transfer RNA reductase1 (GluTR1) and CHLM are reduced.

121 Transfer RNAs represent the largest, most ubiquitous cla

122 d in human circulation, including microRNAs, transfer RNAs, ribosomal RNA, and yRNA fragments.

123 d degradation mechanisms for messenger RNAs, transfer RNAs, ribosomal RNAs, and noncoding RNAs.

124 ific deletion of Trsp, a gene that encodes a transfer RNA (Sec tRNA) required for the insertion of se

125 been shown to participate in both aminoacyl-transfer RNA selection and in peptidyl transferase; it m

126 ploits two rRNA nucleotides also used during transfer RNA selection to drive messenger RNA compaction

127 o acid sequence through repetitive cycles of transfer RNA selection, peptide bond formation and trans

128 the cytochrome P450 superfamily of enzymes, transfer RNA selenocysteine synthase, formiminotransfera

129 stidine, tryptophan and initiator methionine transfer RNA species.

130 However, even the classic transfer RNA structure contains features that are overlo

131 he binding and cleavage of the precursors of transfer RNA substrate.

132 nregulating TOR signalling via LARS-1/leucyl-transfer RNA synthase.

133 ng association of autoantibodies to histidyl-transfer RNA synthetase (HisRS, Jo-1) with interstitial

134 animal models support a key role of histidyl-transfer RNA synthetase (HisRS; also known as Jo-1) in t

135 nse pathway, through inhibiting human prolyl-transfer RNA synthetase (ProRS) to cause intracellular a

136 Twelve patients had anti-histidyl-transfer RNA synthetase autoantibody (anti-Jo-1) and 1 h

137 toantibody (anti-Jo-1) and 1 had anti-alanyl-transfer RNA synthetase autoantibody (anti-PL-12).

138 was used to design a pocket within threonyl-transfer RNA synthetase from the thermophile Pyrococcus

139 was protective in adults with anti-threonyl-transfer RNA synthetase or anti-U RNP autoantibodies (OR

140 l-prolyl-transfer RNA synthetase, glutaminyl-transfer RNA synthetase, elongation factor 2, elongation

141 or in protein biosynthesis (glutamyl-prolyl-transfer RNA synthetase, glutaminyl-transfer RNA synthet

142 zyloxycarbonyl amino acid using a pyrrolysyl transfer RNA synthetase/tRNACUA pair in mammalian cells

143 The Methanococcus jannaschii tyrosyl-transfer-RNA synthetase-tRNA(CUA) (MjTyrRS-tRNA(CUA)) an

144 conserved in evolution, bacterial aminoacyl-transfer RNA synthetases are unable to acylate eukaryoti

145 s (mistranslation) is prevented by aminoacyl transfer RNA synthetases through their accurate aminoacy

146 d translation machinery, including aminoacyl transfer RNA synthetases with specificities for all 20 a

147 st cell machinery proteins such as aminoacyl-transfer RNA synthetases, signal recognition particle, M

148 Autoantibodies to aminoacyl transfer RNA synthetases, such as histidyl (Jo-1), threo

149 te-specific domains from bacterial aminoacyl-transfer RNA synthetases.

150 oribouridine, a modified nucleoside found in transfer RNA that enables both faster and more-accurate

151 reconstruction shows a messenger RNA, three transfer RNAs, the nascent chain, and detailed features

152 esis to date have employed monoaminoacylated transfer RNAs, there have been reports that bisphenylala

153 se-pairs with eIF2-bound initiator methionyl transfer RNA to form a 48S initiation complex.

154 t uses amber and evolved quadruplet-decoding transfer RNAs to encode numerous pairs of distinct unnat

155 would preclude the binding of messenger and transfer RNAs to the ribosome, suggesting that PSRP1 is

156 e aminoacyl-tRNA synthetases covalently link transfer RNAs to their cognate amino acids.

157 e aminoacyl-tRNA synthetases covalently link transfer RNAs to their cognate amino acids.

158 ction mechanism, similar to that employed in transfer RNA translocation on the ribosome by EF-G, tran

159 , deletion of subtelomeric regions, introns, transfer RNAs, transposons, and silent mating loci as we

160 ometry showed that this RNA is aspartic acid transfer RNA (tRNA(Asp)) and that DNMT2 specifically met

161 ecific RNA-RNA complex formed between a host transfer RNA (tRNA(Lys)(3)) and a region at the 5' end o

162 hia coli strain that harbors a Sep-accepting transfer RNA (tRNA(Sep)), its cognate Sep-tRNA synthetas

163 ncluding recruitment of mitochondrial valine transfer RNA (tRNA(Val)) to play an integral structural

164 ved in some adenosine deaminases that act on transfer RNA (tRNA) (ADATs), related enzymes that edit t

165 ) was discovered in the wobble position of a transfer RNA (tRNA) 47 years ago, yet the final biosynth

166 Nase P), the ribonucleoprotein essential for transfer RNA (tRNA) 5' maturation, is challenged in the

167 Accurate transfer RNA (tRNA) aminoacylation by aminoacyl-tRNA syn

168 of genes responsible for amino acid supply, transfer RNA (tRNA) aminoacylation, and protein folding.

169 protein and cell function, requires accurate transfer RNA (tRNA) aminoacylation.

170 a bifunctional molecule that acts as both a transfer RNA (tRNA) and a messenger RNA (mRNA), and SmpB

171 modification that occurs most extensively in transfer RNA (tRNA) and ribosomal RNA (rRNA).

172 clease activity in vitro, but cleaves within transfer RNA (tRNA) anti-codon loops when purified CysK

173 report that both mitochondrial and cytosolic transfer RNA (tRNA) bind to cytochrome c.

174 t affects both amino acid discrimination and transfer RNA (tRNA) binding.

175 n using the in vitro processing of precursor transfer RNA (tRNA) by ribonuclease P as a model system.

176 ss, requiring accurate amino acid selection, transfer RNA (tRNA) charging and mRNA decoding on the ri

177 t shock, or ultraviolet irradiation promotes transfer RNA (tRNA) cleavage and accumulation of tRNA-de

178 sing a messenger RNA (mRNA) and an uncharged transfer RNA (tRNA) cognate to the terminal mRNA codon b

179 Transfer RNA (tRNA) decodes mRNA codons when aminoacylat

180 studies, we show that FthB is a trans-acting transfer RNA (tRNA) editing protein, which hydrolyzes fl

181 The ribosome selects a correct transfer RNA (tRNA) for each amino acid added to the pol

182 ously reported technology termed Fluorescent transfer RNA (tRNA) for Translation Monitoring (FtTM), f

183 er, a recently reported tool for identifying transfer RNA (tRNA) fragments in deep sequencing data, e

184 analyzed the immunostimulatory potential of transfer RNA (tRNA) from different bacteria.

185 entified a chromatin barrier that contains a transfer RNA (tRNA) gene.

186 Transfer RNA (tRNA) genes (tDNAs), which are transcribed

187 Transfer RNA (tRNA) genes and other RNA polymerase III t

188 compare the diversity of chromosomal-encoded transfer RNA (tRNA) genes from 11 eukaryotes as identifi

189 ts localizing within a single nucleolus, and transfer RNA (tRNA) genes present in an adjacent cluster

190 4L), two ribosomal RNA (srRNA and lrRNA), 22 transfer RNA (tRNA) genes, and two copies of D-loop cont

191 bp) and contains 13 protein-coding genes, 22 transfer RNA (tRNA) genes, two ribosomal RNA (rRNA) gene

192 ur frequently at RNA-polymerase-III-occupied transfer RNA (tRNA) genes, which have been implicated in

193 direct entry is central to the processing of transfer RNA (tRNA) in E. coli, one of the core function

194 se to amino acid deprivation in which mature transfer RNA (tRNA) is cleaved in the anticodon loop.

195 Transfer RNA (tRNA) is produced as a precursor molecule

196 Histidine transfer RNA (tRNA) is unique among tRNA species as it c

197 Transfer RNA (tRNA) links messenger RNA nucleotide seque

198 Transfer RNA (tRNA) methylation is necessary for the pro

199 olarity and morphology, vacuole trafficking, transfer RNA (tRNA) modification and other functions.

200 y conserved mitochondrial protein related to transfer RNA (tRNA) modification.

201 h the predicted fraction of correctly folded transfer RNA (tRNA) molecules, thereby revealing a bioph

202 e simultaneously binds up to three different transfer RNA (tRNA) molecules.

203 attachment of amino acids to their matching transfer RNA (tRNA) molecules.

204 ons that are suggested to be associated with transfer RNA (tRNA) movement through the ribosome (trans

205 obe the structural and kinetic parameters of transfer RNA (tRNA) movements within the aminoacyl (A) a

206 ecific ribosomal ribonucleic acid (rRNA) and transfer RNA (tRNA) nucleotides.

207 thesis: production of non-cognate amino acid:transfer RNA (tRNA) pairs by aminoacyl-tRNA synthetases

208 idyltransferases] add CCA onto the 3' end of transfer RNA (tRNA) precursors without using a nucleic a

209 During transfer RNA (tRNA) selection, a cognate codon:anticodon

210 he biophysical and biochemical properties of transfer RNA (tRNA) so that it is optimized for particip

211 Several methanogenic archaea lack cysteinyl-transfer RNA (tRNA) synthetase (CysRS), the essential en

212 ing the ubiquitously expressed enzyme glycyl-transfer RNA (tRNA) synthetase (GlyRS).

213 An orthogonal tryptophanyl-transfer RNA (tRNA) synthetase (TrpRS)-mutant opal suppr

214 tion mutant of rrt-1 that encodes an arginyl-transfer RNA (tRNA) synthetase, an enzyme essential for

215 evelopment and application of the pyrrolysyl-transfer RNA (tRNA) synthetase/tRNA pair for unnatural a

216 Aminoacyl-transfer RNA (tRNA) synthetases (RS) are essential compo

217 Two dissimilar seryl-transfer RNA (tRNA) synthetases (SerRSs) exist in Methan

218 Aminoacyl transfer RNA (tRNA) synthetases are intensely studied en

219 progressively added to cytoplasmic aminoacyl transfer RNA (tRNA) synthetases during evolution.

220 In mammalian cells, specific aminoacyl-transfer RNA (tRNA) synthetases have cytokine functions

221 Protein biosynthesis requires aminoacyl-transfer RNA (tRNA) synthetases to provide aminoacyl-tRN

222 Aminoacyl-transfer RNA (tRNA) synthetases, which catalyze the atta

223 pathologies are caused by editing defects of transfer RNA (tRNA) synthetases, which preserve genetic

224 ternal loop that interacts with the peptidyl-transfer RNA (tRNA) T-loop.

225 Here we report a novel transfer RNA (tRNA) tandem repeat on human chromosome 1q

226 Coupled translocation of messenger RNA and transfer RNA (tRNA) through the ribosome, a process cata

227 A critical element in selecting correct transfer RNA (tRNA) transferring correct amino acid is "

228 Transfer RNA (tRNA) transiently occupies the hybrid P/E

229 Transfer RNA (tRNA) translocates inside the ribosome dur

230 Molecules of transfer RNA (tRNA) typically contain four stems compose

231 ves the movement of messenger RNA (mRNA) and transfer RNA (tRNA) with respect to the ribosome.

232 n and read-through of these stop codons by a transfer RNA (tRNA), although it requires the formation

233 ate of subunit joining is coupled to the IF, transfer RNA (tRNA), and mRNA codon compositions of the

234 t of m(1) A, m(1) G, m(3) C modifications in transfer RNA (tRNA), but they work poorly on m(2)2 G.

235 cysteine, the 21st amino acid, occurs on its transfer RNA (tRNA), tRNA(Sec).

236 g RNAs, such as pre-ribosomal RNA (rRNA) and transfer RNA (tRNA), which are produced by RNA polymeras

237 tmRNA contains a transfer RNA (tRNA)-like domain (TLD), which enters the

238 -2 (VPI-2) is a 57-kb region integrated at a transfer RNA (tRNA)-serine locus that encompasses VC1758

239 ans whose biosynthesis occurs on its cognate transfer RNA (tRNA).

240 n the ribosome, labeled at the L1 stalk, and transfer RNA (tRNA).

241 ibosomal subunit to messenger RNA (mRNA) and transfer RNA (tRNA).

242 s interactions with messenger RNA (mRNA) and transfer RNA (tRNA).

243 RNase P catalyzes the 5' maturation of transfer RNA (tRNA).

244 between the mRNA codon and the anticodon of transfer RNA (tRNA).

245 r the exit channel and Rqc2p over the P-site transfer RNA (tRNA).

246 defining the 3D architecture and dynamics of transfer RNA (tRNA).

247 includes a specific, nuclear genome-encoded, transfer RNA (tRNA[Ser]Sec).

248 iogenin-mediated endonucleolytic cleavage of transfer RNAs (tRNA) leading to an accumulation of 5' tR

249 d translocation of messenger RNAs (mRNA) and transfer RNAs (tRNA) through the ribosome takes place fo

250 Because human tyrosyl transfer-RNA (tRNA) synthetase (TyrRS) translocates to t

251 The sulfur-containing nucleosides in transfer RNA (tRNAs) are present in all three domains of

252 hich include small nucleolar RNAs (snoRNAs), transfer RNAs (tRNAs) and introns, whereas endo-siRNAs c

253 on (PRE) complex and facilitates movement of transfer RNAs (tRNAs) and messenger RNA (mRNA) by one co

254 plays a crucial role in the translocation of transfer RNAs (tRNAs) and messenger RNA (mRNA) during tr

255 scripts are dominated by full-length, mature transfer RNAs (tRNAs) and other small noncoding RNAs (nc

256 Transfer RNAs (tRNAs) and small nucleolar RNAs (snoRNAs)

257 Transfer RNAs (tRNAs) are central to protein synthesis a

258 Posttranscriptional modifications of transfer RNAs (tRNAs) are critical for all core aspects

259 Transfer RNAs (tRNAs) are essential for protein synthesi

260 Eukaryotic transfer RNAs (tRNAs) are exported from the nucleus, the

261 Transfer RNAs (tRNAs) are primarily viewed as static con

262 Transfer RNAs (tRNAs) are the macromolecules that transf

263 In eukaryotes, transfer RNAs (tRNAs) are transcribed in the nucleus yet

264 n the anticodon of Escherichia coli tyrosine transfer RNAs (tRNAs) at position 35.

265 Posttranscriptional modifications of transfer RNAs (tRNAs) at the wobble uridine 34 (U34) bas

266 lves endonucleolytic cleavage of cytoplasmic transfer RNAs (tRNAs) by ribonucleases that are normally

267 gulate the synthesis of 5S ribosomal RNA and transfer RNAs (tRNAs) by RNA polymerase (Pol) III, as we

268 we demonstrate that low levels of mischarged transfer RNAs (tRNAs) can lead to an intracellular accum

269 In all organisms, transfer RNAs (tRNAs) contain numerous modified nucleoti

270 Heretofore, no evidence suggested that transfer RNAs (tRNAs) could also be exploited.

271 ated reductions in the abundance of numerous transfer RNAs (tRNAs) dominated the microarray data and

272 The anticodon stem-loop (ASL) of transfer RNAs (tRNAs) drives decoding by interacting dir

273 final movements of messenger RNA (mRNA) and transfer RNAs (tRNAs) during translocation.

274 Transfer RNAs (tRNAs) function in translational machiner

275 The evolution of alloacceptor transfer RNAs (tRNAs) has been traditionally thought to

276 All canonical transfer RNAs (tRNAs) have a uridine at position 8, invo

277 rimarily responsible for the 5 maturation of transfer RNAs (tRNAs) in all domains of life.

278 Adjacent transfer RNAs (tRNAs) in the A- and P-sites of the ribos

279 Isolated, fully modified native bacterial transfer RNAs (tRNAs) induced significant secretion of I

280 sine/cytosine/adenine (CCA) to the 3' end of transfer RNAs (tRNAs) is essential for translation and i

281 Transfer RNAs (tRNAs) perform essential tasks for all li

282 Besides translation, transfer RNAs (tRNAs) play many non-canonical roles in v

283 Transfer RNAs (tRNAs) represent the single largest, best

284 Transfer RNAs (tRNAs) require the absolutely conserved s

285 leic acids (sRNAs), primarily the 5' ends of transfer RNAs (tRNAs) termed tRNA fragments (trfRNAs).

286 It has been known that mature transfer RNAs (tRNAs) that are encoded in the nuclear ge

287 factor Tu (EF-Tu), which delivers aminoacyl-transfer RNAs (tRNAs) to the ribosome.

288 ed into nascent proteins by misaminoacylated transfer RNAs (tRNAs) used in a coupled transcription/tr

289 In higher eukaryotes, transfer RNAs (tRNAs) with the same anticodon are encode

290 tidyltransferase] adds CCA to the 3' ends of transfer RNAs (tRNAs), a critical step in tRNA biogenesi

291 oncoding RNAs such as small RNAs (sRNAs) and transfer RNAs (tRNAs), establishing a previously unappre

292 each codon is monitored by stable binding of transfer RNAs (tRNAs)-labelled with distinct fluorophore

293 cherichia coli histone-like protein H-NS and transfer RNAs (tRNAs).

294 aryotes involves endonucleolytic cleavage of transfer RNAs (tRNAs).

295 enosine 37 (A37) in several Escherichia coli transfer RNAs (tRNAs).

296 increased amounts of 5' fragments of glycine transfer RNAs (tRNAs).

297 The splicing of two transfer RNAs (trnI-GAU and trnA-UGC) and one ribosomal

298 he inclusion of a disproportionate number of transfer RNAs, which exhibit a conserved secondary struc

299 in synthesis, the ribosome selects aminoacyl-transfer RNAs with anticodons matching the messenger RNA

300 f two basic processes: the aminoacylation of transfer RNAs with their cognate amino acid by the amino