ライフサイエンスコーパス: transferrin

1 receptor-mediated endocytosis of iron-loaded transferrin.

2 y modifying the surface of the liposome with transferrin.

3 ion of HA and the endocytic recycling marker transferrin.

4 aled numerous iron species in plasma besides transferrin.

5 s into the mechanism of Tfr2's regulation by transferrin.

6 ted by supra-physiological concentrations of transferrin.

7 ferric ion to form mono-ferric and di-ferric transferrin.

8 he lysosomal marker LysoTracker and not with transferrin.

9 rtite system for iron acquisition from human transferrin.

10 ucin, with a limit of detection of 20 ng for transferrin.

11 in HEK293 cells inhibited internalization of transferrin, a process that depends on clathrin-mediated

12 sequestered the Fe(III) bound to human holo-transferrin, an iron source of S. aureus, than epiSB.

13 In this study, (89)Zr-transferrin and (18)F-FDG imaging were compared in precl

14 ntration of the glycoproteins up to 70 ng of transferrin and 40 ng of bovine submaxillary mucin, with

15 Transferrin and albumin productions were monitored durin

16 Two serum factors, the iron-carrier protein transferrin and amino acid glutamine, were identified as

17 ween SNA-I and STn-containing glycoproteins (transferrin and bovine submaxillary mucin) was monitored

18 Mutant LCN2 strips iron from transferrin and citrate, and delivers it into the urine.

19 wever, significantly inhibits endocytosis of transferrin and epidermal growth factor.

20 xplain differential effects on the uptake of transferrin and GPI-anchored proteins.

21 Newly absorbed iron binds to plasma transferrin and is distributed around the body to sites

22 a can use catecholamines to obtain iron from transferrin and lactoferrin via uptake pathways involvin

23 sing mTORC1 activity is sufficient to target transferrin and sphingomyelin to the lysosomes.

24 ing, for nonheme iron, the transport protein transferrin and the intracellular iron-storage protein f

25 Internalization of transferrin and these G protein-coupled receptors was al

26 We used bovine RNase B, human transferrin, and bovine fetuin as models to demonstrate

27 cells slower than the HCR of BoNT/A (HCR/A), transferrin, and cholera toxin B.

28 In all VKC samples, levels of serum albumin, transferrin, and hemopexin were found up to 100 times hi

29 sed extravascular hemolysis, saturated serum transferrin, and produced circulating nontransferrin-bou

30 ed to perinuclear vesicles that harbor CD71, transferrin, and Rab8, markers of the recycling endosome

31 nable to serve as a receptor for iron-loaded transferrin appeared to fully rescue most animals.

32 Using the abundant serum glycoprotein transferrin as a model, it has been shown that B. fragil

33 Y-1 in virus-infected cells colocalized with transferrin as determined by confocal microscopy, indica

34 Using albumin and transferrin as models of cis-proline-containing proteins

35 Single substitutions in transferrin at rapidly evolving sites reverse TbpA bindi

36 In vivo, the intravenous injection of transferrin-bearing dendriplex more than doubled the gen

37 rain barrier, we propose to investigate if a transferrin-bearing generation 3-polypropylenimine dendr

38 In this work, we demonstrated that novel transferrin-bearing multilamellar vesicles entrapping al

39 These results suggest that transferrin-bearing polypropylenimine dendrimer is a hig

40 s administration of tocotrienol entrapped in transferrin-bearing vesicles resulted in tumor suppressi

41 The neisserial transferrin binding proteins (Tbps) comprise a bipartite

42 Iron-loaded transferrin binds to transferrin receptor 1 on the surfa

43 Moreover, iron-loaded transferrin blocked MT2-mediated Tfr2 cleavage, providin

44 nd liver function, and reduced levels of non-transferrin bound iron and plasma labile iron.

45 but no difference in the accumulation of non-transferrin bound iron or ferritin.

46 rsinia enterocolitica O9) by controlling non-transferrin-bound iron (NTBI) rather than iron-transferr

47 Biodistribution studies revealed increased transferrin-bound iron accumulation in the kidneys of al

48 thy women, the production of circulating non-transferrin-bound iron is determined by the rate and amo

49 n of iron, the production of circulating non-transferrin-bound iron may contribute to an increased ri

50 Non-transferrin-bound iron rather than transferrin-bound-iro

51 At 4 h, serum non-transferrin-bound iron reached peaks with geometric mean

52 The highest concentrations of non-transferrin-bound iron resulted from the administration

53 Little or no circulating non-transferrin-bound iron resulted from the consumption of

54 effects on the production of circulating non-transferrin-bound iron resulting from the oral administr

55 area under the curve over 8 h for serum non-transferrin-bound iron was positively correlated with th

56 The value of hepcidin, non-transferrin-bound iron, and reticulocyte indexes is bein

57 ired that the first species, assigned to non-transferrin-bound iron, imports faster into organs than

58 mutants reduce redox activity typical of non-transferrin-bound iron.

59 olysis, and the formation of circulating non-transferrin-bound iron.

60 Non-transferrin-bound iron rather than transferrin-bound-iron appears to play the dominant role

61 ter into organs than the second, assigned to transferrin-bound-iron.

62 d glycoproteins bovine ribonuclease B, human transferrin, bovine fetuin and human alpha1-acid glycopr

63 of in vitro studies, it was speculated that transferrin can bind Ti(IV) assisted by a synergistic an

64 tein antigen to the iron transport molecule, transferrin, can significantly enhance mucosal immune re

65 Carbohydrate deficient transferrin (CDT) is the most specific serum biomarker o

66 We identified carboxymethylated transferrin (Cm-Tf) as a new ADAMDEC1 substrate and dete

67 Transferrin-coated endocytic gold nanorod cargoes initia

68 In vivo results revealed that the transferrin-coated NPs can effectively be transported ac

69 We show that the administration of transferrin-coated TiO2 nanoparticles and clinically use

70 ansferrin-bound iron (NTBI) rather than iron-transferrin concentration.

71 rrin saturation (cutoff 55%), and high serum transferrin concentrations (cutoff 1.6 g/L) were associa

72 Transferrin conjugated haemagglutinin induced a signific

73 ract than intranasally delivered antigen and transferrin conjugation had a more marked effect on subl

74 From these studies we conclude that transferrin conjugation of antigen is effective at boost

75 ther conjugating influenza haemagglutinin to transferrin could improve the immune response to subling

76 We then showed that transferrin deglycosylation occurs in vivo when B. fragi

77 es the bioavailability of iron in urine by a transferrin-dependent mechanism.

78 ctivation, and surprisingly, upregulation of transferrin despite increased levels of ferritin.

79 unosensing experiment is realized with human transferrin (dissociation constant Kd~10(-8) M(-1)).

80 cal release of the host iron-binding protein transferrin during RSV infection promotes P. aeruginosa

81 exposure of trypanosomes to AEE788 inhibited transferrin endocytosis, altered cell morphology, and de

82 accumulation of early endosomes and impaired transferrin endocytosis.

83 Transferrin excretion was significantly increased in alb

84 yptic digests of bovine serum albumin (BSA), transferrin factor (TF), and human immunoglobulins (IgG)

85 copper, ceruloplasmin, non-Cp copper, iron, transferrin, ferritin, and APOE genotype.

86 ate Examination, APOE4, iron, non-Cp copper, transferrin, ferritin, hypercholesterolemia, and hyperte

87 2 has an inhibitory effect on endocytosis of transferrin, FM-4-64, and the leucine rich repeat recept

88 However, the paclitaxel-transferrin formulation showed a lower level of toxicity

89 igher antitumor activity than the paclitaxel-transferrin formulation, achieving a 93.3% tumor inhibit

90 s virus G protein, recycling of internalized transferrin from endosomes, or degradation of EGF recept

91 deglycosylate this protein in vitro and that transferrin glycans can provide the sole source of carbo

92 Analysis of transferrin glycosylation revealed severe dysglycosylati

93 munogold) to map the available epitopes on a transferrin grafted silica particle (SiO2-PEG8-Tf) as a

94 Infected mice treated with intravenous human transferrin had improved survival and reduced microbial

95 and laminin, but not other proteins, such as transferrin, heparin, bovine serum albumin, mucin, or co

96 of gold nanoparticles) with proteins (human transferrin, human serum albumin, and ovalbumin).

97 ased formulation stabilized by serum protein transferrin in a non-covalent manner.

98 peptic digestion of the 80 kDa glycoprotein transferrin in the course of HDX MS experiments is carri

99 Apo-transferrin increased the formation of hydroxyl radicals

100 ments with fluorescence labelled dextran and transferrin indicate that SO1861 induces the release of

101 at ProINS-Tf was converted to active insulin-transferrin (INS-Tf) via the transferrin (Tf)-receptor-m

102 Lalphas knockout (XLKO) pups showed enhanced transferrin internalization.

103 lin rescues the EFA6A-mediated inhibition of transferrin internalization.

104 SNX9 in XLKO Ocy454 cells prevented enhanced transferrin internalization.

105 ting greater right-to-left shunting); higher transferrin iron saturation index; intravenous iron use

106 Transferrin is a promising, novel antimicrobial agent th

107 (89)Zr-transferrin is a useful tool to interrogate MYC via TfR-

108 We show that the iron transport protein transferrin is engaged in ancient and ongoing evolutiona

109 ars specific, as general endocytic uptake of transferrin is unaffected in RNASEK-depleted cells.

110 Transferrin labeled with (89)Zr has successfully identif

111 ong-term survivors displayed higher ferritin/transferrin levels and lower transferrin saturation.

112 On the contrary, serum iron and transferrin levels were decreased in ICU subjects with l

113 hat in FXTAS iron accumulated in the stroma, transferrin levels were decreased in the epithelial cell

114 Hemopexin, transferrin, mammaglobin B, and secretoglobin 1D were fo

115 Transferrin-mediated iron uptake by regenerating myofibe

116 FACS analysis showed that transferrin-mediated targeting enhanced the association

117 Furthermore, neither high concentrations of transferrin nor knock-out of cytosolic lipid peroxidases

118 nt-negative mutant Rab20T19N does not affect transferrin or dextran 70 kDa uptake.

119 f the MT2 gene, TMPRSS6, incubation with apo-transferrin or the membrane-impermeable iron chelator, d

120 norepinephrine in the presence of iron-bound transferrin or with free iron.

121 We hypothesized that (89)Zr-transferrin PET will noninvasively detect MYC and TfR an

122 ing patients by body mass index, prealbumin, transferrin, phosphate, urinary urea nitrogen, and nitro

123 a novel pulmonary delivery system of siRNA, transferrin-polyethylenimine (Tf-PEI), to selectively de

124 g was insufficient for induced tubulation of transferrin-positive endosomal recycling compartments (E

125 l precursors that can be graded by levels of transferrin receptor (CD71) expression.

126 /proerythroblast stage, a point at which the transferrin receptor (CD71) is upregulated, iron is impo

127 owever, the selective tropism of P vivax for transferrin receptor (CD71)-positive reticulocytes remai

128 nt glycoprotein, GP1, and cell surface human transferrin receptor (hTfR1).

129 that is calculated from ferritin and soluble transferrin receptor (sTfR) allows for the evaluation of

130 ons.We assessed the relation between soluble transferrin receptor (sTfR) concentrations and inflammat

131 wich assay (SA) for the detection of soluble transferrin receptor (sTfR), a biomarker of IDA, on a ph

132 time, measured by sFer, hemoglobin, soluble transferrin receptor (sTfR), and estimated total body ir

133 rically to include plasma ferritin), soluble transferrin receptor (sTfR), and total body iron (TBI) w

134 line hemoglobin, ferritin, hepcidin, soluble transferrin receptor (sTfR), and transferrin were measur

135 in (SF), transferrin saturation, and soluble transferrin receptor (sTfR), as well as erythrocyte prot

136 ess hemoglobin, serum ferritin (SF), soluble transferrin receptor (sTfR), hepcidin, serum iron, eryth

137 t external cues induced up-regulation of the transferrin receptor (TfR) and down-regulation of ferrit

138 ealed differences in the dynamic behavior of Transferrin Receptor (TfR) and Langerin proteins.

139 The P2Ns manifest transferrin receptor (TfR) colocalization in ex vivo int

140 Antibodies to transferrin receptor (TfR) have potential use for therap

141 Increased surface expression of transferrin receptor (TfR) is a downstream event of MYC

142 Transferrin receptor (TFR) is an important iron transpor

143 rom raccoons do not efficiently bind the dog transferrin receptor (TfR) or infect dog cells, a single

144 Transferrin receptor (TfR) represents a unique target fo

145 in the form of tunable nanosystems (NS) for transferrin receptor (TfR) utilizing gambogic acid (GA),

146 Similar to the constitutive endocytosis of transferrin receptor (TfR), ligand- triggered endocytosi

147 NHE5 is associated with transferrin receptor (TfR)- and Rab11-positive recycling

148 fect on the clathrin-mediated endocytosis of transferrin receptor (TfR).

149 consequence, IRP1 target genes, such as the transferrin receptor (TfR1), a membrane-associated glyco

150 PN), the iron efflux pump, is decreased, and transferrin receptor (TFR1), the iron importer, is incre

151 transmembrane protease, serine 6 (TMPRSS6), transferrin receptor (TFR2), N-acetyltransferase 2 (aryl

152 biquitin C (UBC) in head and neck cancer and Transferrin receptor (TFRC) and beta-Glucuronidase (GUSB

153 Transferrin receptor 1 (Tfr1) facilitates cellular iron

154 thogenic arenaviruses of the same clade, use transferrin receptor 1 (TfR1) of their host species to e

155 had a homozygous p.Tyr20His substitution in transferrin receptor 1 (TfR1), encoded by TFRC.

156 The antibody engages the GP1 site that binds transferrin receptor 1 (TfR1)-the host cell surface rece

157 iated with the placental nonheme Fe importer transferrin receptor 1 (TfR1).

158 ated with decreased ferritin H and increased transferrin receptor 1 (TfR1).

159 GPC architecture and share a host receptor, transferrin receptor 1 (TfR1).

160 he metabolite stearic acid (C18:0) and human transferrin receptor 1 (TFR1; also known as TFRC) as mit

161 restricted to reticulocytes expressing both transferrin receptor 1 (Trf1 or CD71) and the Duffy anti

162 were decreased in the epithelial cells, and transferrin receptor 1 distribution was shifted from the

163 Iron-loaded transferrin binds to transferrin receptor 1 on the surface of most body cells

164 pathogenic New World arenaviruses use human transferrin receptor 1 to enter cells.

165 We demonstrate that loss of transferrin receptor 1, but not loss of ferroportin, can

166 However, loss of transferrin receptor 1, involved in iron uptake, caused

167 Mutations in transferrin receptor 2 (TfR2) cause a rare form of the h

168 Transferrin receptor 2 (TFR2) contributes to hepcidin re

169 regulatory genes, hemochromatosis (Hfe) and transferrin receptor 2 (Tfr2).

170 n), HFE (hemochromatosis protein), and TfR2 (transferrin receptor 2), these proteins do not control t

171 0.22; beta = -0.17 (95% CI: -0.25, -0.09)], transferrin receptor [R(2) = 0.23; beta = 2.79 (95% CI:

172 ptake of systemically dosed antibodies (anti-transferrin receptor [TfR] bispecific versus control ant

173 Expression of transferrin receptor and 24p3R were reduced in tubules f

174 nin virus (JUNV) failed to down-regulate the transferrin receptor and did not induce superinfection e

175 determined that CSCs preferentially require transferrin receptor and ferritin, two core iron regulat

176 brogates the somatodendritic polarity of the transferrin receptor and several glutamate receptor type

177 lathrin-mediated internalization of both the transferrin receptor and the beta2 adrenergic receptor.

178 We further found that the cell surface transferrin receptor and the glutamine-fueled intracellu

179 leaves unchanged the rate by which MC4R and transferrin receptor are constitutively excluded from th

180 e calculated from serum ferritin and soluble transferrin receptor concentrations, can be used to asse

181 CD4, the asialoglycoprotein receptor, or the transferrin receptor eliminates intramembrane proteolysi

182 This was reflected in increased transferrin receptor expression and increased splenic ir

183 oehner et al. (2014) describe a modular anti-transferrin receptor Fab approach for shuttling therapeu

184 tures, known mediators of rapid recycling of transferrin receptor from endosomes.

185 pid stress disrupted later steps of MC4R and transferrin receptor internalization to endosomes as wel

186 tus (ferritin level, transferrin saturation, transferrin receptor level, reticulocyte hemoglobin leve

187 Moreover, quantification of transferrin receptor mRNA in single cells agrees well wi

188 Type 1 transferrin receptor mRNA was unexpectedly decreased in

189 Transferrin receptor mRNA, which contains two highly con

190 posomal preparation was also targeted to the transferrin receptor of cancer cells by modifying the su

191 >/=1 biomarker of iron [ferritin or soluble transferrin receptor or vitamin A status (retinol-bindin

192 the modified CLC reduces beta1-integrin and transferrin receptor recycling, as well as cell migratio

193 ing complex pathway, its knockdown arresting transferrin receptor recycling.

194 cysteines 556 and 558 on the surface of the transferrin receptor resulting in subsequent endocytic u

195 carnivores due to its interactions with the transferrin receptor to mediate infection.

196 300Lys) altered the binding of the capsid to transferrin receptor type 1 (TfR), particularly during v

197 umours respect to surrounding liver, whereas transferrin receptor was up-regulated.

198 screened, including CD54 (ICAM-1) and CD71 (transferrin receptor).

199 Serum ferritin, serum transferrin receptor, and hemoglobin concentrations were

200 on and vitamin A biomarkers (ferritin, serum transferrin receptor, and retinol binding protein) in se

201 e binding partners of these deposits (sCD89, transferrin receptor, and transglutaminase 2) decreased

202 ytosis and coincided with the recruitment of transferrin receptor, VAMP3, and dynamin-2.

203 DNA damage, p53 induced FTH1 and suppressed transferrin receptor, which regulates iron entry into ce

204 sion of hepcidin and increased expression of transferrin receptor-1 and erythroferrone, suggesting th

205 egulates iron homeostasis components such as transferrin receptor-1 and ferritin-H in hepatic and ske

206 n-responsive elements present in the UTRs of transferrin receptor-1 and ferritin-H transcripts.

207 iron-responsive elements present in UTRs of transferrin receptor-1 and ferritin-H.

208 fectively depleted cellular Fe, resulting in transferrin receptor-1 up-regulation, ferritin down-regu

209 Increased transferrin receptor-1, decreased ferritin-H, and increa

210 Hemojuvelin (HJV), HFE, and transferrin receptor-2 (TfR2) facilitate this process pr

211 s been associated with mutations in the HFE, transferrin receptor-2 (TfR2), and hemojuvelin (HJV) gen

212 nclude newly identified interactions between transferrin receptor-2 and the erythropoietin receptor.

213 ize, low cellular toxicity and the efficient transferrin receptor-mediated uptake render the AspA tag

214 eceptor, while New World arenaviruses hijack transferrin receptor.

215 ue and change in plasma ferritin and soluble transferrin receptor.

216 ed for hemoglobin, serum ferritin, and serum transferrin receptor.

217 iron, including HFE and, in rarer instances, transferrin-receptor 2 and hemojuvelin, or make its rece

218 y recognized CPV host-to different carnivore transferrin receptors (TfRs) using single-particle track

219 ed in dynamin-dependent endosomes labeled by transferrin receptors (TfRs).

220 eceptors and plasma membrane lipids, such as transferrin receptors and sphingomyelin, are delivered t

221 ron can effectively reach the brain by using transferrin receptors for crossing the blood-brain barri

222 ereas the CME of constitutively internalized transferrin receptors is mainly dependent on the ubiquit

223 ritin, transferrin saturation, serum soluble transferrin receptors, and the serum soluble transferrin

224 transferrin receptors, and the serum soluble transferrin receptors-ferritin index are more accurate t

225 Finally, adjunctive transferrin reduced the emergence of rifampin-resistant

226 versus 37.5% of compound heterozygotes with transferrin saturation > 50%; p = 0.003), serum ferritin

227 low iron levels (cutoff 10.5 mumol/mL), low transferrin saturation (cutoff 55%), and high serum tran

228 wth rates were very strongly correlated with transferrin saturation (p < 0.0001 in all cases).

229 increases in AUC for serum iron (P < 0.01), transferrin saturation (P < 0.001), and nontransferrin-b

230 tion studies for serum iron, serum ferritin, transferrin saturation (SAT) and total iron binding capa

231 One-half of them (10 of 22) proposed transferrin saturation (TSAT) as an alternative or compl

232 dose, intravenous (IV) iron dose, ferritin, transferrin saturation (TSAT) concentration, parathyroid

233 Subjects on FC had increased ferritin and transferrin saturation (TSAT) levels compared with subje

234 erythropoiesis, and significantly decreased transferrin saturation and lung iron stores after 2 week

235 /fl);Cre(+) mice exhibited approximately 90% transferrin saturation and massive liver iron overload,

236 males showed differences across genotypes in transferrin saturation levels (100% of homozygotes versu

237 erum ferritin level of 101 to 299 ng/mL with transferrin saturation of less than 20%.

238 Higher transferrin saturation or serum iron concentrations were

239 The median baseline transferrin saturation was 8% (range, 2-58%).

240 Transferrin saturation was also associated with a greate

241 of septic ICU subjects, low iron levels and transferrin saturation went along with a nonlethal outco

242 ancer), higher serum iron concentrations and transferrin saturation were associated with increased ri

243 um ferritin, total iron-binding capacity and transferrin saturation), serum hepcidin and genome-wide

244 um iron, total iron binding capacity (TIBC), transferrin saturation, and ferritin in a Hispanic/Latin

245 study-wise type 1 error for serum ferritin, transferrin saturation, and intravenous iron and erythro

246 ical data, including hemoglobin, serum iron, transferrin saturation, and serum ferritin concentration

247 sed indicators, such as serum ferritin (SF), transferrin saturation, and soluble transferrin receptor

248 no significant difference between groups in transferrin saturation, erythrocyte zinc protoporphyrin

249 icantly, but it had no discernible effect on transferrin saturation, iron-deficient erythropoiesis, h

250 Measurement of serum ferritin, transferrin saturation, serum soluble transferrin recept

251 parameters of iron metabolism, particularly transferrin saturation, that reflect serum iron availabi

252 d evaluation of iron status (ferritin level, transferrin saturation, transferrin receptor level, reti

253 els, and serum iron correlated strongly with transferrin saturation.

254 M significantly increased serum ferritin and transferrin saturation.

255 higher ferritin/transferrin levels and lower transferrin saturation.

256 eived iron depletion therapy; all had normal transferrin saturation.

257 1.83 (95% CI: 1.21, 2.76; P < 0.01); HR for transferrin saturation: 1.68 (95% CI: 1.18, 2.38; P < 0.

258 : 2.45 (95% CI:1.12, 5.34; P < 0.05); HR for transferrin saturation: 1.90 (95% CI:1.02, 3.56; P < 0.0

259 ntrol (ferritin=628+/-367 ng/ml [mean+/-SD]; transferrin saturation=30%+/-12%; P<0.001 for both).

260 eters (ferritin=899+/-488 ng/ml [mean+/-SD]; transferrin saturation=39%+/-17%) versus subjects on act

261 ed knockdown of cyclophilins B and C delayed transferrin secretion but surprisingly resulted in more

262 Removal of insulin-transferrin-selenium completely inhibited the effect of

263 Mass spectrometry of transferrin showed a loss of complete N-glycans and the

264 Human serum transferrin (sTf) is a protein that mediates the transpo

265 ongoing evolutionary conflicts with TbpA, a transferrin surface receptor from bacteria.

266 s provide the first glimpse into the citrate-transferrin synergism in the regulation of Ti(IV) bioact

267 Conclusion:(89)Zr-transferrin targets human TNBC primary tumors significan

268 Head-to-head comparison showed that (89)Zr-transferrin targets TNBC tumors significantly better (P

269 elates from host-derived proteins, including transferrin (TbpA), lactoferrin (LbpA), and hemoglobin (

270 Validation studies confirmed lower serum transferrin (Tf) and ceruloplasmin levels in ACLF and AC

271 Clathrin-mediated endocytosis of transferrin (Tf) and its cognate receptor (TfR1) is a ce

272 ions between endosomes containing iron-bound transferrin (Tf) and mitochondria have been shown to fac

273 we report that PrP(C) promotes the uptake of transferrin (Tf) and non-Tf-bound iron (NTBI) by the kid

274 ptides was tested for the ability to enhance transferrin (Tf) association with cells.

275 tions, despite blocking of the receptor with transferrin (Tf) noncompetitively, i.e., independently o

276 ive endosomal pathway distinct from the fast transferrin (Tf) receptor recycling pathway.

277 However, the transferrin (Tf) receptor system, composed of TbpA and T

278 The trafficking kinetics of Glut4, the transferrin (Tf) receptor, and LRP1 were quantified in a

279 n with epidermal growth factor (EGF) but not transferrin (Tf) trafficking pathways as shown by live c

280 lized to HCHS/SOL, including variants at the transferrin (TF), hemochromatosis (HFE), fatty acid desa

281 Apo-transferrin (Tf), the primary carrier of soluble iron in

282 common mechanism used by proteins, including transferrin (Tf), to traverse the BBB.

283 active insulin-transferrin (INS-Tf) via the transferrin (Tf)-receptor-mediated pathway in hepatoma c

284 early endosomal markers and is recruited to transferrin (Tfn)-containing vesicles during endocytic r

285 ere previously defined using markers such as transferrin (TfR) and polymeric IgA (pIgR) receptors.

286 causing upregulation of the iron transporter transferrin, the top differentially expressed gene compa

287 B also indirectly compromised the ability of transferrin to chelate iron, as iron chelation combined

288 coupled QDs capped with bis(LA)-PEG-COOH to transferrin to facilitate intracellular uptake.

289 he TGN, as well as recycling of internalized transferrin to the plasma membrane.

290 knockdown of which stalled transit of a1 and transferrin-transferrin receptor, decreased proton efflu

291 , associates with TfR1 and partially rescues transferrin uptake in patient-derived fibroblasts, sugge

292 ld-type but not mutant TfR1 rescued impaired transferrin uptake in patient-derived fibroblasts.

293 ndocytosis and plays a critical role in iron/transferrin uptake in vivo.

294 infection approximately 5,000-fold, whereas transferrin uptake, early endosome organization, and dyn

295 ssion of endophilin delayed both fission and transferrin uptake.

296 ors--chondroitin sulfate, serum albumin, and transferrin--using analytical techniques capable of reso

297 The serum protein transferrin was selected for use after evaluating the st

298 ng with receptor-mediated internalization of transferrin, was also significantly decreased upon drug

299 in, soluble transferrin receptor (sTfR), and transferrin were measured in 45 patients with confirmed

300 le the surface-coated protein ligands (e.g., transferrin) were demonstrated to alter the NP cellular

301 erate correlation of hepcidin, ferritin, and transferrin with inflammatory parameters was noted.