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1 tinol-binding protein (vitamin A), and iron (transferrin receptor).
2 screened, including CD54 (ICAM-1) and CD71 (transferrin receptor).
3 curium-transferrin complexes by the cognate transferrin receptor.
4 d with clathrin and the IR, but not with the transferrin receptor.
5 cycling endosomes positive for Rab11 and the transferrin receptor.
6 cling endosomes, where it interacts with the transferrin receptor.
7 calization of CD44 with the nonraft protein, transferrin receptor.
8 mal markers, but showed coincidence with the transferrin receptor.
9 a non-ER resident type II protein, the human transferrin receptor.
10 eceptor, while New World arenaviruses hijack transferrin receptor.
11 ed for hemoglobin, serum ferritin, and serum transferrin receptor.
12 nds on transferrin-bound iron uptake via the transferrin receptor.
13 were observed for serum ferritin and soluble transferrin receptor.
14 r (CIMPR) without affecting that of TGN46 or transferrin receptor.
15 ermined from hemoglobin, serum ferritin, and transferrin receptor.
16 t up unless first transfected with the mouse transferrin receptor.
17 ind to the extracellular domain of the mouse transferrin receptor.
18 beyond changes to expression of ESAG6/7, the transferrin receptor.
19 ar compartment which also contained Rab5 and transferrin receptor.
20 s apoptosis through its interaction with the transferrin receptor.
21 ue and change in plasma ferritin and soluble transferrin receptor.
22 nsferrin uptake and lysosomal degradation of transferrin receptors.
23 stitution impairs the endocytic recycling of transferrin receptors.
24 lex class I-like protein that interacts with transferrin receptors.
25 gested that circulating levels of shed human transferrin receptor 1 (hTfR1) are regulated by PC7.
26 ly regulate iron metabolism genes, including transferrin receptor 1 (TfR1) and ferritin H and L subun
28 ates entry into grivet and bat cells through transferrin receptor 1 (TfR1) binding but that OCEV glyc
29 alpha-dystroglycan by Lassa fever virus and transferrin receptor 1 (TfR1) by certain New World clade
30 g activity but did not affect ferritin H and transferrin receptor 1 (TfR1) expression, whereas knockd
36 thogenic arenaviruses of the same clade, use transferrin receptor 1 (TfR1) of their host species to e
37 ty of these viruses to use various mammalian transferrin receptor 1 (TfR1) orthologs, including those
38 receptors, alpha-dystroglycan (alpha-DG) and transferrin receptor 1 (TfR1), are expressed in polarize
41 ransferrin receptor 2 (TfR2) is a homolog of transferrin receptor 1 (TfR1), the receptor responsible
42 The antibody engages the GP1 site that binds transferrin receptor 1 (TfR1)-the host cell surface rece
47 he metabolite stearic acid (C18:0) and human transferrin receptor 1 (TFR1; also known as TFRC) as mit
48 tomography (PET) radiotracer that binds the transferrin receptor 1 (TFRC, CD71) with high avidity.
49 restricted to reticulocytes expressing both transferrin receptor 1 (Trf1 or CD71) and the Duffy anti
50 l iron pools and increased the expression of transferrin receptor 1 and iron regulatory protein 2 con
51 were decreased in the epithelial cells, and transferrin receptor 1 distribution was shifted from the
52 k has demonstrated the requirement for human transferrin receptor 1 for virus entry, and the absence
54 this, we found that IOP1 knockdown increases transferrin receptor 1 mRNA levels and decreases ferriti
56 rom transferrin without increasing levels of transferrin receptor 1 or the uptake of transferrin.
57 cellular iron was associated with increased transferrin receptor 1 protein and mRNA levels and incre
58 Western blot analysis revealed a decline in transferrin receptor 1 protein levels following inductio
64 rived cell lines through a low-pH-dependent, transferrin receptor 1-independent mechanism, suggesting
67 sing expression cloning, we identified human transferrin receptor-1 (TfR1) as an important receptor f
68 rristatin (NSC30611) acts by down-regulating transferrin receptor-1 (TfR1) via receptor degradation.
69 sion of hepcidin and increased expression of transferrin receptor-1 and erythroferrone, suggesting th
70 egulates iron homeostasis components such as transferrin receptor-1 and ferritin-H in hepatic and ske
73 , divalent metal transporter-1, ferritin and transferrin receptor-1 and greater accumulation of iron.
74 fectively depleted cellular Fe, resulting in transferrin receptor-1 up-regulation, ferritin down-regu
77 Mutations in the transmembrane glycoproteins transferrin receptor 2 (TfR2) and HFE are associated wit
80 utations in hemochromatosis protein (HFE) or transferrin receptor 2 (TFR2) cause hereditary hemochrom
87 hereditary hemochromatosis proteins HFE and transferrin receptor 2 may intersect with the BMP pathwa
88 n), HFE (hemochromatosis protein), and TfR2 (transferrin receptor 2), these proteins do not control t
89 atosis-related proteins hemojuvelin, HFE and transferrin receptor 2, also regulates hepcidin expressi
91 (BMP6), hereditary hemochromatosis protein, transferrin receptor 2, matriptase-2, neogenin, BMP rece
92 he hereditary hemochromatosis protein (HFE), transferrin-receptor 2 (TfR2), hemojuvelin, hepcidin, or
93 iron, including HFE and, in rarer instances, transferrin-receptor 2 and hemojuvelin, or make its rece
95 s been associated with mutations in the HFE, transferrin receptor-2 (TfR2), and hemojuvelin (HJV) gen
96 nclude newly identified interactions between transferrin receptor-2 and the erythropoietin receptor.
97 tes cellular iron uptake by interacting with transferrin receptor, a crucial protein during erythropo
98 ovary cells with a GFP-tagged transmembrane transferrin receptor, a well-known benchmark of membrane
100 issorting of AP-1B-dependent cargos, such as transferrin receptor and a truncated low-density lipopro
101 nt receptors in T cell progenitors: CD71 the transferrin receptor and CD98 a subunit of L-amino acid
102 M images identified < or =200 nm clusters of transferrin receptor and clathrin light chain at < or =2
103 nin virus (JUNV) failed to down-regulate the transferrin receptor and did not induce superinfection e
104 uryi, has been recently demonstrated to bind transferrin receptor and exhibit potential anticancer ef
105 determined that CSCs preferentially require transferrin receptor and ferritin, two core iron regulat
107 lass I partially localized together with the transferrin receptor and internalized transferrin in end
108 many types of cancer cell lines by targeting transferrin receptor and modulating nuclear factor-kappa
109 th factor type-I receptor localized with the transferrin receptor and Rab11-positive endosomes in a l
110 brogates the somatodendritic polarity of the transferrin receptor and several glutamate receptor type
111 lathrin-mediated internalization of both the transferrin receptor and the beta2 adrenergic receptor.
113 teractions between the basolateral signal of transferrin receptor and the medium subunits of both AP-
114 eceptors and plasma membrane lipids, such as transferrin receptors and sphingomyelin, are delivered t
115 host cell iron (e.g. up-regulation of Tfrc (transferrin receptor) and Lcn2 (lipocalin 2)), facilitat
116 l recycling endosomes positive for Rab11 and transferrin receptor, and CvpA membrane interactions wer
117 alysis was used to determine the presence of transferrin receptor, and ELISA was used to determine to
118 n the aged RPE/choroid, whereas transferrin, transferrin receptor, and ferroportin mRNAs did not chan
120 coexpressing Dendra2-hemagglutinin, PAmKate-transferrin receptor, and PAmCherry1-beta-actin fusion c
121 on and vitamin A biomarkers (ferritin, serum transferrin receptor, and retinol binding protein) in se
122 e binding partners of these deposits (sCD89, transferrin receptor, and transglutaminase 2) decreased
123 ritin, transferrin saturation, serum soluble transferrin receptors, and the serum soluble transferrin
124 ndosomes co-localized with subsets of Rab5-, transferrin receptor-, and Lamp1/Lysotracker-marked comp
126 = 200 nm, height (h) = 200 nm) labeled with transferrin receptor antibody (NP-OKT9) or human transfe
127 nhibit receptor activity simultaneously; and transferrin receptor antibody, to target the tumor vascu
128 leaves unchanged the rate by which MC4R and transferrin receptor are constitutively excluded from th
129 constitutively recycled, HSP90-independent, transferrin receptor are found within modified endosomes
132 rin uptake is due to a decrease in available transferrin receptor at the cell surface, and not to a s
134 approach using expression of a biotinylated transferrin receptor (bTfnR) and controlling its local c
135 ith the endosomal markers including EEA1 and transferrin receptors but also with the TGN marker synta
136 ers and found that the TM motifs of CD40 and transferrin receptor, but not that of CD45, could functi
137 rine brain endothelioma cells overexpressing transferrin receptors, by about 1.4-fold and 2.3-fold co
141 /proerythroblast stage, a point at which the transferrin receptor (CD71) is upregulated, iron is impo
142 owever, the selective tropism of P vivax for transferrin receptor (CD71)-positive reticulocytes remai
146 n calculated from serum ferritin and soluble transferrin receptor concentrations allows for the evalu
147 e calculated from serum ferritin and soluble transferrin receptor concentrations, can be used to asse
148 cality of current biomarkers such as soluble transferrin-receptor concentrations and others, and caus
150 creased early in flight, and transferrin and transferrin receptors decreased later, which indicated t
151 which stalled transit of a1 and transferrin-transferrin receptor, decreased proton efflux, and reduc
152 For iron, this regulation is achieved by transferrin receptor, DMT1, and ferroportin, whereas mam
153 pe SH3TC2, but not mutant SH3TC2, influences transferrin receptor dynamics, consistent with a functio
154 CD4, the asialoglycoprotein receptor, or the transferrin receptor eliminates intramembrane proteolysi
155 equence into the proteins sonic hedgehog and transferrin receptor enabled good in vitro and in vivo P
156 erfering dynamin mutant (Dyn/K44A) inhibited transferrin receptor endocytosis, it had no effect on ph
158 rformed PALM imaging using PAmCherry1-tagged transferrin receptor expressed alone or with photoactiva
160 ginase-1 and YM1 transcription and increased transferrin receptor expression by phagocytic cells.
162 oehner et al. (2014) describe a modular anti-transferrin receptor Fab approach for shuttling therapeu
163 d levels of ferritin and increased levels of transferrin receptor, features characteristic of cellula
164 transferrin receptors, and the serum soluble transferrin receptors-ferritin index are more accurate t
165 ron can effectively reach the brain by using transferrin receptors for crossing the blood-brain barri
167 normal values: ferritin < or = 8.7 microg/L, transferrin receptors > or = 8.4 microg/mL, and transfer
169 that mislocalize the dendritic marker human transferrin receptor (hTfR), we found that kinesin heavy
171 Consistent with this, there was stronger transferrin receptor immunoreactivity in the light-expos
173 the protein level, decreased transferrin and transferrin receptor, increased ferritin and ceruloplasm
174 ical early endosomal recycling receptor, the transferrin receptor, indicating that this viral protein
175 pid stress disrupted later steps of MC4R and transferrin receptor internalization to endosomes as wel
176 ugh integrin beta1 endocytosis was impaired, transferrin receptor internalization was unaffected.
178 e for Rabenosyn-5 in determining the fate of transferrin receptors internalized by clathrin-mediated
179 e for the first time that endocytosis of the transferrin receptor is a regulated process that require
180 ereas the CME of constitutively internalized transferrin receptors is mainly dependent on the ubiquit
182 tus (ferritin level, transferrin saturation, transferrin receptor level, reticulocyte hemoglobin leve
183 iron availability, as noted by a decrease in transferrin receptor levels and iron uptake from transfe
184 ) and negatively correlated with the soluble transferrin receptor/log(ferritin) ratio but not correla
185 c characterization, these studies prove that transferrin receptor-mediated endocytosis is a viable me
187 ize, low cellular toxicity and the efficient transferrin receptor-mediated uptake render the AspA tag
192 posomal preparation was also targeted to the transferrin receptor of cancer cells by modifying the su
193 >/=1 biomarker of iron [ferritin or soluble transferrin receptor or vitamin A status (retinol-bindin
195 r iron uptake by endocytosis of Fe(3+)-bound transferrin receptors, or after lysosomal degradation of
196 stricted to this membrane cargo, however, as transferrin receptors packaged in the same population of
198 ically isolated labeled RBCs and in isolated transferrin receptor-positivereticulocytes was used to d
200 0.22; beta = -0.17 (95% CI: -0.25, -0.09)], transferrin receptor [R(2) = 0.23; beta = 2.79 (95% CI:
201 activating protein for Rab4A that regulates transferrin receptor recycling and EGFR trafficking and
202 , but not the inactive R494A mutant, reduces transferrin receptor recycling but has no effect on tran
203 ation of Bves function specifically inhibits transferrin receptor recycling, and results in gastrulat
204 the modified CLC reduces beta1-integrin and transferrin receptor recycling, as well as cell migratio
207 cysteines 556 and 558 on the surface of the transferrin receptor resulting in subsequent endocytic u
209 that is calculated from ferritin and soluble transferrin receptor (sTfR) allows for the evaluation of
210 < or = 0.05), and concentrations of soluble transferrin receptor (sTfR) and hemoglobin and the red c
211 ons.We assessed the relation between soluble transferrin receptor (sTfR) concentrations and inflammat
212 serum ferritin decreased (P < 0.0001), serum transferrin receptor (sTfR) increased (P < 0.0001), and
214 n, ferritin, C-reactive protein, and soluble transferrin receptor (sTfR) strongly predicted incorpora
215 wich assay (SA) for the detection of soluble transferrin receptor (sTfR), a biomarker of IDA, on a ph
216 time, measured by sFer, hemoglobin, soluble transferrin receptor (sTfR), and estimated total body ir
218 rically to include plasma ferritin), soluble transferrin receptor (sTfR), and total body iron (TBI) w
219 line hemoglobin, ferritin, hepcidin, soluble transferrin receptor (sTfR), and transferrin were measur
220 in (SF), transferrin saturation, and soluble transferrin receptor (sTfR), as well as erythrocyte prot
221 timated on the basis of plasma iron, soluble transferrin receptor (sTfR), ferritin, transferrin, tran
222 ess hemoglobin, serum ferritin (SF), soluble transferrin receptor (sTfR), hepcidin, serum iron, eryth
223 iciency, defined by raised levels of soluble transferrin receptor (sTfR), was investigated in 98 pati
225 r trafficking of the endogenously expressing transferrin receptor, suggesting ethanol does not have a
226 followed an innovative approach of combining transferrin receptor targeting with enhanced cell penetr
227 T-cells and induced large vacuoles marked by transferrin receptor, TCR, and SNAREs implicated in TCR-
228 o specifically adsorb His-tagged transferrin-transferrin receptor (Tf-TfR) complexes from insect and
229 epidermal growth factor receptor (EGFR) and transferrin receptor (TfnR) exhibited changes in steady-
232 t external cues induced up-regulation of the transferrin receptor (TfR) and down-regulation of ferrit
234 on depletion, using iron chelators targeting transferrin receptor (TfR) and ribonucleotide reductase
235 aracterized basolateral protein markers, the transferrin receptor (TfR) and the vesicular stomatitis
236 tosis, plasma membrane receptors such as the transferrin receptor (TfR) are internalized by a caveola
239 res and impairs recycling of the transferrin-transferrin receptor (TfR) complex to the plasma membran
241 characterize the organization of pIgA-R and transferrin receptor (TFR) in endocytic membranes of pol
242 Our results identify a role for PICALM in transferrin receptor (TfR) internalization and demonstra
245 te of iron acquisition in vertebrates is the transferrin receptor (TfR) mediated endocytotic pathway,
248 rom raccoons do not efficiently bind the dog transferrin receptor (TfR) or infect dog cells, a single
251 target a protein complex of transferrin and transferrin receptor (TfR) through a non-canonical allos
252 n alone (BI-ferritin) or the ratio of plasma transferrin receptor (TfR) to ferritin (BI-TfR/ferritin)
253 in the form of tunable nanosystems (NS) for transferrin receptor (TfR) utilizing gambogic acid (GA),
254 monoclonal antibody (MAb) against the mouse transferrin receptor (TfR), and these fusion proteins ar
255 monoclonal antibody (MAb) against the mouse transferrin receptor (TfR), and this fusion protein is d
257 Similar to the constitutive endocytosis of transferrin receptor (TfR), ligand- triggered endocytosi
258 g because of the active participation of the transferrin receptor (TFR), salt, a chelator, lobe-lobe
260 monoclonal antibody (MAb) against the mouse transferrin receptor (TfR), which is designated as the c
261 monoclonal antibody (MAb) against the mouse transferrin receptor (TfR), which is designated the cTfR
266 of 3 abnormal ferritin (< 12 mug/L), soluble transferrin receptor (TfR; > 8.3 mg/L), or zinc protopor
267 anine parvovirus (CPV) capsids with cellular transferrin receptors (TfR) on the surfaces of live feli
268 ptake of systemically dosed antibodies (anti-transferrin receptor [TfR] bispecific versus control ant
270 nd significance of positive selection on the transferrin receptor TfR1, a housekeeping protein requir
272 consequence, IRP1 target genes, such as the transferrin receptor (TfR1), a membrane-associated glyco
273 PN), the iron efflux pump, is decreased, and transferrin receptor (TFR1), the iron importer, is incre
275 transmembrane protease, serine 6 (TMPRSS6), transferrin receptor (TFR2), N-acetyltransferase 2 (aryl
276 biquitin C (UBC) in head and neck cancer and Transferrin receptor (TFRC) and beta-Glucuronidase (GUSB
277 y recognized CPV host-to different carnivore transferrin receptors (TfRs) using single-particle track
279 icroscopy and biochemical analyses show that transferrin receptor, the cellular receptor for canine p
280 ot other cell surface receptors, such as the transferrin receptor, the receptor tyrosine kinase TrkA,
281 0 mg/kg and calculated from the log ratio of transferrin receptor to ferritin (the body iron model) t
282 ressed in vivo and has been coexpressed with transferrin receptor to increase iron loading in cells.
285 d an increased dependence of Cd1 GP on human transferrin receptor type 1 (hTfR-1) for entry, which ma
286 ized by different abilities to use the human transferrin receptor type 1 (hTfR1) protein as a recepto
287 ve feline panleukopenia virus (FPV) bind the transferrin receptor type 1 (TfR) to infect their host c
288 300Lys) altered the binding of the capsid to transferrin receptor type 1 (TfR), particularly during v
294 rtantly, the constitutive internalization of transferrin receptors was unaffected by either treatment
295 ed blood cell distribution width and soluble transferrin receptor were elevated (P < 0.05), and serum
296 status biomarkers (ie, ferritin and soluble transferrin receptor) were significantly associated with
297 points, internalized GPR17 co-localized with transferrin receptor, whereas at later times it partiall
298 interfering RNA changed the localization of transferrin receptor, which is a marker of the recycling
299 DNA damage, p53 induced FTH1 and suppressed transferrin receptor, which regulates iron entry into ce
300 tress, including a failure to upregulate the transferrin receptor, which we show is a novel stress ta
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