ライフサイエンスコーパス: transformed cell line

1 vels to suppress cellular proliferation in a transformed cell line.

2 in the presence of RI and is cytotoxic to a transformed cell line.

3 l cell line (NRKE) to obtain a conditionally transformed cell line.

4 er hypermethylation of 5 to 10 genes in each transformed cell line.

5 solubilized MHC molecules purified from EBV-transformed cell lines.

6 receptor agonist-induced cell death in a few transformed cell lines.

7 h the nuclear matrix in viral- and non-viral transformed cell lines.

8 PP) inhibits chemotactic motility of several transformed cell lines.

9 ic crisis followed by the emergence of fully transformed cell lines.

10 in the major fraction of tumors and in many transformed cell lines.

11 fibroblasts, smooth muscle cells, or several transformed cell lines.

12 normal human tissues but not in malignantly transformed cell lines.

13 studies that previously have been limited to transformed cell lines.

14 nd STRL33/BONZO/TYMSTR and GPR15/BOB HOS.CD4 transformed cell lines.

15 ems with the facile in vitro manipulation of transformed cell lines.

16 peripheral blood mononuclear cells and some transformed cell lines.

17 any human tumors as well as v-abl- and v-src-transformed cell lines.

18 the 1.9-kb Survivin transcript expressed in transformed cell lines.

19 distension and eventual death of a number of transformed cell lines.

20 itutive phosphorylation is not seen in v-fgr-transformed cell lines.

21 at rapidly induces apoptosis in a variety of transformed cell lines.

22 lls, resulting in the efficient formation of transformed cell lines.

23 iocarcinomas we studied, and in a variety of transformed cell lines.

24 ments to localize to virological synapses in transformed cell lines.

25 tion in the virally transformed and oncogene-transformed cell lines.

26 fe of the TGFalpha transcript in the various transformed cell lines.

27 lity to CD3/28 costimulated T cells and some transformed cell lines.

28 ion candidates in 22 breast cancer and 9 non-transformed cell lines.

29 in other skin-derived cell immortalized and transformed cell lines.

30 OCS1 in both transfected cells and in HTLV-1-transformed cell lines.

31 ontamination of retroviral vectors made from transformed cell lines.

32 region (TPR) in Tax-immortalized and HTLV-I-transformed cell lines.

33 ibian epithelial cells, neurons, and several transformed cell lines.

34 tagged RECQL4 are nuclear and cytoplasmic in transformed cell lines.

35 alpha and reduces hypoxic gene expression in transformed cell lines.

36 on but down-regulated in primary cancers and transformed cell lines.

37 responsible for oncogenic malignancy in the transformed cell lines.

38 single splice form of Ca(v)3.2 expressed in transformed cell lines.

39 extracts of both nontransformed and oncogene-transformed cell lines.

40 They are also expressed in many transformed cell lines.

41 with those from populations of independently transformed cell lines.

42 human tumors as well as in v-abl- and v-src-transformed cell lines.

43 ate to low levels of TMEFF1 in most of these transformed cell lines.

44 protein whose expression was lost in virally transformed cell lines.

45 r originally isolated in revertants of H-ras-transformed cell lines.

46 ctivate TGF-beta2 promoter in normal and Akt-transformed cell lines.

47 ilable for study are restricted generally to transformed cell lines.

48 ociated with telomere length in DNA from EBV-transformed cell-lines.

49 Stimulation was seen for both transformed cell lines (293T and HeLa cells) and primary

50 dermal JB6 cells and the corresponding H-ras-transformed cell line 30.7b Ras 12.

51 e in animals, we characterized a variant ras-transformed cell line, 749r-1, which was resistant to ph

52 decrease in the growth rate of many putative transformed cell lines after 6 weeks of culturing in sel

53 The transformed cell line alphaAalphaBKO1 derived from alpha

54 nd by antigen presentation using a Theileria-transformed cell line and autologous T cells from Theile

55 horylation has also been observed in various transformed cell line and in primary malignant tissue, s

56 ells were restimulated in vitro with the EBV transformed cell line and tested for cytolytic activity.

57 the experimental design that includes a non-transformed cell line and three tumorigenic cell lines,

58 d development is that they rely primarily on transformed cell lines and animal models that substantia

59 iruses because HRV growth is limited in most transformed cell lines and animal models.

60 he abnormal clones, Epstein-Barr virus (EBV)-transformed cell lines and CD34+ cells were analyzed fro

61 in (E555K) was stable in patient-derived EBV-transformed cell lines and cell lines transfected with e

62 sine triphosphate (GTP) in untransformed and transformed cell lines and determine this phenomenon dep

63 The combination of peptide binding to EBV-transformed cell lines and DQ transgenic mice provides a

64 In these reports, transformed cell lines and drug-selected cells have been

65 PRKX gene in 12 different human tissues and transformed cell lines and found that, among these tissu

66 ide range of tumor cells as well as in vitro-transformed cell lines and has been implicated as a new

67 i in seven diverse cell lines, including six transformed cell lines and human induced pluripotent ste

68 s are expressed at varying levels in all the transformed cell lines and human tumors tested, further

69 r, survivin becomes prominently expressed in transformed cell lines and in all the most common human

70 rotein that is absent or inactive in several transformed cell lines and lung tumors.

71 (HDACis) on HIV reactivation in established transformed cell lines and primary CD4(+) T cells.

72 ed to determine how HDACis reactivate HIV in transformed cell lines and primary cells.

73 These cell types include transformed cell lines and primary hematopoietic progeni

74 Here, using both transformed cell lines and primary neurons, we investiga

75 5(-/-)/VpreB1(-/-)/VpreB2(-/-) Abelson virus-transformed cell lines and reconstituted these cells wit

76 q/G11 protein was extracted from control and transformed cell lines and reconstituted with exogenous

77 r human T-cell leukemia virus type 1 (HTLV1)-transformed cell lines and results in apoptosis and redu

78 In many virus-transformed cell lines and spontaneous tumours, these ge

79 CCR1, CCR2b, CCR3, CCR5, and CXCR4 U87MG.CD4 transformed cell lines and STRL33/BONZO/TYMSTR and GPR15

80 -STAT complexes were detected in all Bcr/Abl-transformed cell lines and they were supershifted by ant

81 ability to protect against extinction in the transformed cell lines and to function as a chromatin bo

82 ercaptopropanol induced apoptosis in several transformed cell lines and transformed primary cultures

83 HRVs, as they generally replicate poorly in transformed cell lines, and host range restriction preve

84 r, these reports almost exclusively utilized transformed cell lines, and many employed transfection o

85 TLV-1 isolates derived from primary sources, transformed cell lines, and molecular clones.

86 e kinase overexpressed in many human tumors, transformed cell lines, and rapidly proliferating tissue

87 modification is defective in many tumors and transformed cell lines, and the extent of hypomodificati

88 up-regulated in various types of tumors and transformed cell lines, and the overexpression of COX-2

89 ects tumor growth in these two sets of H-ras-transformed cell lines, and this negative effect is not

90 However almost all of these studies utilized transformed cell lines, and thus the involvement of othe

91 ssed in adult and embryo-derived stem cells, transformed cell lines, and tumors.

92 In addition, the atx-transfected ras-transformed cell lines appeared to produce tumors that w

93 These L. monocytogenes-infected Qa-1b-transformed cell lines are lysed by BALB/c (Qa-1b)- or C

94 lls, mesenchymal stem cells, fibroblasts and transformed cell lines, as well as a method for identify

95 o virus replication and apoptosis in several transformed cell lines, as well as to replication and pa

96 mtrII-transformed cell lines, at both early and late passage,

97 s in transformed cells using a Kirsten virus-transformed cell line (ATCC NRK1569) as a model system.

98 ylation studies are currently performed from transformed cell lines because of the ability to generat

99 ild-type and HM175/P16 viruses in two stably transformed cell lines (BT7-H and FRhK-T7) which constit

100 ce apoptosis in a variety of tumorigenic and transformed cell lines but not in many normal cells.

101 assembly were linked in three different ras-transformed cell lines but not in SV40- or RSV-transform

102 toxic protein that induces apoptosis of many transformed cell lines but not of normal tissues, even t

103 xport of prohibitin occurs preferentially in transformed cell lines, but not in untransformed or prim

104 lysates from human Epstein-Barr virus (EBV)-transformed cell lines by immunoblot analysis.

105 e of cell types, including primary cells and transformed cell lines, by as much as 10(4)-fold.

106 uppression, whereas the human papillomavirus-transformed cell lines, CaSki and HeLa, did not.

107 Transformed cell lines containing the exogenous M or R e

108 performed with a panel of nontransformed and transformed cell lines cultured at 37 and 39.5 degrees C

109 Compared with other transformed cell lines, cultured iCSCL-10A cells exhibit

110 Measurement of mRNA decay rates in stably transformed cell lines demonstrated that premature nonse

111 In these cells and transformed cell lines, depletion of Hili increased leve

112 undation for this system is an Abelson virus-transformed cell line derived from RAG-1(-/-) mice that

113 5 and into MRC-SV1, a simian virus 40 (SV40)-transformed cell line derived from them.

114 Mouse embryonic stem (ES) cells are non-transformed cell lines derived directly from the pluripo

115 Cells of renal or intestinal origin and transformed cell lines derived from breast, stomach, bon

116 and this effect appears to be restricted to transformed cell lines derived from the early stages of

117 Expression analyses on 10 different human transformed cell lines detect exclusive XYLT2 expression

118 is surrounded by insulator elements, stably transformed cell lines display consistent enhancer-depen

119 dical center, we analyzed Epstein-Barr virus-transformed cell lines established from peripheral blood

120 In transformed cell lines established from the primary cell

121 overexpressed in certain tumor types and all transformed cell lines examined.

122 EBV(+) lymphomas and transformed cell lines exhibited abundant expression of

123 ll lines investigated, while the other three transformed cell lines exhibited loss of USF2 activity.

124 NF-kappaB) in the prevention of apoptosis in transformed cell lines exposed to tumor necrosis factor

125 ffects of SSeCKS, we developed conditionally transformed cell lines (expressing ts72v-src) with tetra

126 The FMR1 origin is active in transformed cell lines, fibroblasts from healthy individ

127 on in both human and murine immortalized and transformed cell lines following induction of wild-type

128 t shock could be observed in simian virus 40 transformed cell lines from human TM.

129 WASP was present in two of four EBV-transformed cell lines from WAS patients.

130 Expression of the USP transcripts in MDV-transformed cell lines further substantiates this hypoth

131 AA also inhibited growth of the bcr-abl-transformed cell line H7.bcr-abl A54.

132 No transformed cell line had only the LMP1 delta185-211 gen

133 The transformed cell line has been maintained for over 30 ge

134 Moreover, EGF-R-transformed cell lines have constitutive EGF-R activity,

135 s, worms, mammalian embryonic stem cells and transformed cell lines have found well-positioned nucleo

136 v-Rel-transformed cell lines have longer telomeres than untran

137 Abelson murine leukemia virus-transformed cell lines have provided a critical model sy

138 loser to those in transfected cells and some transformed cell lines, hsp70 is continuously bound by B

139 urine astrocytes and neurons, and in several transformed cell lines (human (SH-SY5Y) and murine (N1E-

140 osure to lysates or supernatants of necrotic transformed cell lines, human dendritic cells (DCs) unde

141 d by their ability to slow the growth of ras transformed cell lines in soft agar.

142 und when primary isolates adapt to growth in transformed cell lines in vitro has little to do with al

143 ected B cells generate neoplasms in vivo and transformed cell lines in vitro.

144 The AGLCL Epstein-Barr virus (EBV) growth-transformed cell line is incapable of inducing tumors in

145 ressor activity, and phenotypic reversion of transformed cell lines is accompanied by increased lysyl

146 demonstrate that the wild-type p53 in HTLV-1-transformed cell lines is not fully active.

147 ibition by farnesyl-transferase inhibitor in transformed cell lines is overcome by ectopic expression

148 Furthermore, in the Bcr-Abl transformed cell line, K562 endogenous GCKR and CrkL coi

149 er IL-2 stimulation of an Epstein-Barr virus-transformed cell line (LCL) from an X-SCID patient with

150 e inhibition of telomerase activity in v-Rel-transformed cell lines led to apoptosis within 24 h.

151 ssion is downregulated in breast cancers and transformed cell lines making it an attractive marker fo

152 A transformed cell line (MDB) was exposed to microsomes pr

153 owth and cytoskeletal functions in a BCR-ABL-transformed cell line model was investigated.

154 1 by RNA-mediated interference in the HTLV-1-transformed cell line MT-2 resulted in increased IFN-bet

155 ere obtained for both blood (N = 24) and EBV-transformed cell-line (N = 36) DNA samples from men aged

156 e 7 had no effect on SARS-CoV replication in transformed cell lines, nor did it alter the induction o

157 ARPE-19 is a spontaneously transformed cell line of human RPE that is widely studie

158 y in cells originated from malignant tumors: transformed cell line of non-cancer origin, HEK293, was

159 Screening more than 100 EBV-transformed cell lines of GC origin identified 6 lines l

160 nd effects of TFIIB knockdown in primary and transformed cell lines on cellular functionality and glo

161 In neurons and transformed cell lines, opioid receptors are coupled to

162 In contrast, DCs exposed to apoptotic transformed cell lines or necrotic lysates of primary ce

163 EBNA2 and EBNA-LP was not detectable in EBV-transformed cell lines or transfected type I Burkitt's c

164 o-2 cell lines but not in HT-29, T84, SW-480 transformed cell lines, or native colonic epithelial cel

165 Stably transformed cell lines overexpressing a dominant negativ

166 Transformed cell lines producing foreign proteins were r

167 nd the expression of miR-302a in primary and transformed cell lines promotes an increase in S-phase a

168 This contrasts with the Tax-transformed cell lines, PX1 (fibroblast) and MT4 (lympho

169 t to be substrate-driven, studies in several transformed cell lines reported that glucose deprivation

170 ncogenic Ras up-regulates autophagy, and Ras-transformed cell lines require autophagy for mitochondri

171 expression of Dab2 in F9 cells as well as in transformed cell lines results in increased Axin express

172 the proteasome by EGCG in several tumor and transformed cell lines results in the accumulation of tw

173 In 2001, a transformed cell line RGC-5 was developed from the rat r

174 Experiments were carried out with an SV40 transformed cell line (rMC-1) that exhibits the phenotyp

175 The transformed cell lines show increased expression of matr

176 Analysis of supernatants of necrotic transformed cell lines showed them to be enriched in the

177 are consistently elevated in EBV- and HTLV1-transformed cell lines stably expressing shIRF4.

178 In many human cancers and transformed cell lines, Stat3 is persistently activated,

179 In addition to commonly used transformed cell lines such as HeLa, CHO, Cos-7, and 293

180 0- to 100-fold-less infectious than rAAV2 in transformed cell lines (such as HEK-293, HeLa, and CV1-T

181 Several earlier studies in transformed cell lines suggested that normoxic stabiliza

182 ephosphorylation of GAPa-p62 is defective in transformed cell lines, suggesting a possible role for p

183 ly in plasmid transfection assays in several transformed cell lines, suggesting that the cis-regulato

184 Its expression in fetal liver and in transformed cell lines suggests CRD-BP is an oncofetal p

185 essing viral proteins but not with an HTLV-1-transformed cell line that does not express viral protei

186 In order to propagate this mutant virus, transformed cell lines that express the UL37 gene produc

187 o move away from the often nonphysiological, transformed cell lines that have been used for decades i

188 In contrast all stable transformed cell lines that were tested, derived either

189 One of these transformed cell lines, the A-U3 cell line, was evaluate

190 nto the bioenergetic states of progressively transformed cell lines, the effect of oncogenes on small

191 sal levels of adhesion through L-selectin in transformed cell lines, the rapid increase in ligand bin

192 ment, in cancers, and in immortalized and/or transformed cell lines, the significance of which is unc

193 cromolar concentrations, induce a variety of transformed cell lines to differentiate.

194 show that the effect of exposure of several transformed cell lines to metformin varies with carbon s

195 alpha was not due to an inability of BCR/ABL-transformed cell lines to migrate in general, as spontan

196 al cells demonstrated relatively low levels (transformed cell line) to high levels (primary cell line

197 In T cells and transformed cell lines used as model systems, HIV-1 asse

198 ificant changes between the immortalized and transformed cell lines using peptide mass fingerprinting

199 o frameshift mutations in Epstein Barr virus-transformed cell lines, using reverse-transcriptase poly

200 PKABA1 produced in transformed cell lines was able to phosphorylate synthet

201 Cp usage in the HVP- and RhEBV-transformed cell lines was detected by S1 nuclease prote

202 o directly analyze whether the p53 in HTLV-1-transformed cell lines was transcriptionally active and

203 In a K-ras transformed cell line we experimentally assessed glutami

204 e why EBV infected blasts go on to establish transformed cell lines, we performed global transcriptom

205 In this study, we show that when BCR-ABL-transformed cell lines were selected for imatinib resist

206 samples of a panel of mouse immortalized or transformed cell lines were shown to express abundant le

207 ies of immortalized and human papillomavirus-transformed cell lines were used to demonstrate that the

208 v-ErbB:ER construct and these conditionally transformed cell lines will be useful to further elucida

209 d with wild-type CSB (CS-B wt), and a stably transformed cell line with a point mutation in the ATPas

210 Finally, treatment of HTLV-1-transformed cell lines with 17-DMAG suppressed HTLV-1 re