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1 practitioner's credibility depends on them "transforming".
2 ts separately, rs1344110 in pituitary tumour-transforming 1 interacting protein (PTTG1IP) and rs34598
3 nificant co-expression with pituitary tumour-transforming 1, the binding factor of PTTG1lP, and with
4 tes that E. umbellata expanded aggressively, transforming a large proportion of the original open fie
5 f profiles we used computational methods for transforming a list of peptides constituting the mimotop
6 er, the molecular mechanisms responsible for transforming a normal brain into an epileptic one remain
7 cture with different amounts of flexibility, transforming a protein into membrane coordinates and opt
9 TRK2, and BRAF kinases that exhibited potent transforming activity and conferred sensitivity to FDA-a
10 Our results confirmed other reports that the transforming activity of BRAF fusions results from trunc
11 ammal species, cetaceans lack the enzyme for transforming an important intermediate precursor (perflu
12 of river ecosystems, including their role in transforming and transporting carbon (C), nitrogen (N),
13 l polyomavirus (MCPyV) DNA and express viral transforming antigens, sT and tLT, but the role of these
14 richia coli strains expressing either NHase (transforming benzonitrile to benzamide) or amidase (furt
16 ck copolymers enables morphological control, transforming brittle materials into mechanically tough b
18 usceptible Programmed cell death in immunity transforming Ca(2+) signals into reactive oxygen species
22 each oncogene may initiate pulmonary LCH by transforming different types of lung-resident myeloid ce
23 uggesting that CtsM is important for marking transforming DNA, but not for transformation itself.
27 dylinositol 3-kinase (PI3K) is emerging as a transforming factor in cancer, but the mechanism of tran
29 ic hydrogenation develop incredibly rapidly, transforming from a largely hypothetical possibility to
33 and associated with increased production of transforming growth factor (TGF) beta and interleukin (I
34 hymal self-organisation relies on restricted transforming growth factor (TGF) beta signalling, which
35 l-mesenchymal transition (EMT) is induced by transforming growth factor (TGF)-beta and facilitates tu
37 n factor 15 (GDF15), a distant member of the transforming growth factor (TGF)-beta family, is a secre
38 expression in response to two members of the transforming growth factor (TGF)-beta family, TGF-beta1
41 promote SCC tumor initiation in concert with transforming growth factor (TGF)-beta present in the tum
44 hological formation, neural development, and transforming growth factor (TGF)-beta signalling of the
45 C or TDFSM controls, was highly dependent on transforming growth factor (TGF)-beta, but not promoted
49 first documented protein known to stimulate transforming growth factor (TGF)-beta1 to -beta3 transla
51 on of pro-fibrotic growth factors, including transforming growth factor (TGF)-beta1, in human granulo
52 trate the potential of this platform for: i) transforming growth factor (TGF)-beta1-induced spatial d
54 e cells (SMCs) were stimulated with elevated transforming growth factor (TGFbeta) and its signaling p
57 fibroblast growth factor 2, IL-7, IL-15, and transforming growth factor alpha) but lower levels of th
58 E-536) is a novel fusion protein that blocks transforming growth factor beta (TGF beta) superfamily i
59 reatment there was a significant increase in transforming growth factor beta (TGF-beta) and concomita
64 l as thymic stromal lymphopoietin (TSLP) and transforming growth factor beta (TGF-beta) plasma levels
65 ave previously determined that type I and II transforming growth factor beta (TGF-beta) receptors (Tb
66 , which in turn activates the STAT3-mediated transforming growth factor beta (TGF-beta) signaling pat
67 plays a central role in the amplification of transforming growth factor beta (TGF-beta) signaling res
68 extracellular matrix, or decrease canonical transforming growth factor beta (TGF-beta) signaling.
69 the prototypical prosclerotic growth factor, transforming growth factor beta (TGF-beta), is thought t
70 cules include collagen types I, III, and IV, transforming growth factor beta (TGF-beta), TGF-beta rec
73 er and serves as a common downstream node of transforming growth factor beta (TGFbeta) and bone morph
78 mong tumour-associated inflammatory factors, transforming growth factor beta (TGFbeta) is regarded as
79 a family of signal transduction molecules in transforming growth factor beta (TGFbeta) ligand pathway
80 as TIEG1, plays essential roles in mediating transforming growth factor beta (TGFbeta) signaling and
81 d that these proteoglycans were dependent on transforming growth factor beta (TGFbeta) signaling.
82 2-HER3 signaling, or A83-01, an inhibitor of transforming growth factor beta (TGFbeta) signaling.
84 in (IL6) beta2SP(+/-) LSCs was activated by transforming growth factor beta (TGFbeta)-activated kina
86 SMAD family member 2 (SMAD2), SMAD3, SMAD4, transforming growth factor beta 1 (TGFB1), TGFB2, TGFB3,
88 e subclass expressed many genes regulated by transforming growth factor beta 1 that mediate immunosup
89 Plasmid transfection was used to modulate transforming growth factor beta 2 (TGF-beta2) gene expre
90 lated type 2 (IL-4 and IL-5) and regulatory (transforming growth factor beta [TGF-beta]) cytokines.
91 yte-macrophage colony-stimulating factor and transforming growth factor beta alone, whereas CD14(+) c
92 D206 and arginase-1) and secretory products (transforming growth factor beta and interleukin-6) and d
93 in-1, p21-activated kinase, microRNA 21, and transforming growth factor beta are also being explored
97 art by defective desmosomes and dysregulated transforming growth factor beta production and signaling
98 growth factor beta 1 (TGFB1), TGFB2, TGFB3, transforming growth factor beta receptor 1 (TGFBR1), and
99 iptional regulator SMAD6, which inhibits the transforming growth factor beta signaling pathway, is re
100 iptional regulator SMAD6, which inhibits the transforming growth factor beta signaling pathway, is re
102 lowing isotropic chondrogenic induction with transforming growth factor beta to set up a dual-compart
104 cytokines (interleukin 6, 1beta, and 23 and transforming growth factor beta) restored CD4+ Th17 cell
105 local fibroblast activation by secretion of transforming growth factor beta, and a preneoplastic or
106 hogenetic protein, fibroblast growth factor, transforming growth factor beta, and Wnt signaling, and
107 h as proliferation-progenitor, proliferation-transforming growth factor beta, and Wnt-catenin beta1.
108 that these HCV-infected hepatocytes express transforming growth factor beta, which activates stromal
111 V-A6, and EV-D68 3C(pro) proteins all cleave transforming growth factor beta-activated kinase 1 (TAK1
113 th death domain as an upstream regulator and transforming growth factor beta-activated kinase 1 as a
114 CSF-1)-dependent donor macrophages, induce a transforming growth factor beta-high environment locally
115 during glucose starvation of HeLa cells and transforming growth factor beta-induced epithelial-to-me
116 scle (Asm) area with decreased periostin and transforming growth factor beta-positive cells within As
119 kophilin-2 (PKP2) in cardiomyocytes elevates transforming growth factor beta1 (TGF-beta1) and p38 mit
120 eal injury typically involves fibrosis, with transforming growth factor beta1 (TGF-beta1) as one of i
121 al immunosensor for the determination of the transforming growth factor beta1 (TGF-beta1) cytokine co
126 that the integrin alphavbeta8 and its latent transforming growth factor beta1 (TGFbeta1) protein liga
128 th factor receptor 1, 2, and 3; osteopontin; transforming growth factor beta1 and beta2; thrombospond
129 es the release of active MMP2 in response to transforming growth factor beta1 and rescues tissue inte
130 hemokine ligand 5 [CCL5]) and profibrogenic (transforming growth factor beta1, collagen type 4 alpha
132 es showed aberrant tumor necrosis factor and transforming growth factor signaling in metastatic cells
133 ung disease induced by the overexpression of transforming growth factor-alpha (TGF-alpha), establishe
134 deleted fibroblasts had higher expression of transforming growth factor-alpha (Tgfa) mRNA and secrete
135 e found to be an important source of cardiac transforming growth factor-beta (TGF-beta) and PAI-1 reg
139 teins are central mediators in the canonical transforming growth factor-beta (TGF-beta) signaling pat
142 SIGNIFICANCE STATEMENT We show that reducing Transforming growth factor-beta (TGF-beta) signaling pro
143 umulation, extracellular matrix degradation, transforming growth factor-beta (TGF-beta) signaling, co
144 ere we show that epidermal Hedgehog (Hh) and Transforming growth factor-beta (TGF-beta) signalling me
145 eover, RNA-sequencing analysis shows altered transforming growth factor-beta (TGF-beta) signalling.
148 o known as MIC-1, is a distant member of the transforming growth factor-beta (TGF-beta) superfamily a
149 lammatory drug-activated gene-1 (NAG-1) is a transforming growth factor-beta (TGF-beta) superfamily p
152 f regulatory T cells (Treg cells) induced by transforming growth factor-beta (TGF-beta), we identifie
153 that the STAT3 signaling pathway attenuates transforming growth factor-beta (TGF-beta)-induced respo
154 injury produced by airway disease triggers a transforming growth factor-beta (TGF-beta)-mediated epig
156 and also required a novel intersection with transforming growth factor-beta (TGF-beta)/SMAD signalin
157 d that DMF blocks the profibrotic effects of transforming growth factor-beta (TGFbeta) in SSc skin fi
159 Hepatic stellate cell (HSC) activation and transforming growth factor-beta 1 (TGF-beta1) expression
160 tine leads to release of fossilized factors (transforming growth factor-beta [TGF-beta] and bone morp
161 lation of IL-1 receptor-associated kinase 1, transforming growth factor-beta activated kinase-1, Ikap
162 vs E12.5, while abundance of elements of the transforming growth factor-beta and insulin-like growth
164 diac reprogramming was similarly enhanced on transforming growth factor-beta and WNT inhibition and w
166 pilla inductive signaling pathways including transforming growth factor-beta and Wnt/beta-catenin.
167 hat further induction of Mmp-2 expression by transforming growth factor-beta I was blocked by Meg3 si
170 tion of cytotoxic T-lymphocyte antigen 4 and transforming growth factor-beta partially abrogated the
171 capacity to suppress multiple genes from the transforming growth factor-beta pathway and the producti
173 eceptor type 1C (ACVR1C), a component of the transforming growth factor-beta receptor superfamily.
174 own-regulation of thrombospondin 1, a latent transforming growth factor-beta receptor, and transcript
176 which was partly attributable to blockade of transforming growth factor-beta signaling in dermal fibr
177 ncreased expression of profibrotic genes and transforming growth factor-beta signaling in SFBLs.
178 was determined on mitochondrial function and transforming growth factor-beta signaling in vitro and i
184 molecular markers of fibrosis (collagen and transforming growth factor-beta) and immunostaining for
186 owed tumor necrosis factor-alpha, IFN-gamma, transforming growth factor-beta, and IL-13 as potential
187 tifibrotic strategies include antagonists of transforming growth factor-beta, connective tissue growt
188 in kinases, tight junctions, focal adhesion, transforming growth factor-beta, vascular smooth muscle
190 a/b and thereby modulating the expression of transforming growth factor-beta-activated kinase 1 (TAK1
191 GCD is caused by a point mutation in the transforming growth factor-beta-induced (TGFBI) gene, lo
192 Mechanistically, sphingosine ameliorates transforming growth factor-beta-induced collagen accumul
193 based selective miRNA analysis revealed that transforming growth factor-beta-induced enhanced express
194 control fibroblasts and attenuated basal and transforming growth factor-beta-induced expression of CC
195 RNA-21 levels suppressed the IL10 effects on transforming growth factor-beta-induced fibrotic signali
196 evel, IL10 treatment significantly inhibited transforming growth factor-beta-induced transdifferentia
198 anonical Hh pathway, involving TGFbeta/SMAD (transforming growth factor-beta/Sma- and Mad-related fam
199 pression of Hmga2 enhances the activation of transforming growth factor-beta1 (TGF-beta1) and Cxcl12
200 interactions with soluble mediators such as transforming growth factor-beta1 (TGF-beta1) and mechani
203 s inhibited by increased accumulation of the transforming growth factor-beta1 (TGF-beta1) in skeletal
204 ibrogenic phenotype through the induction of transforming growth factor-beta1 (TGF-beta1), collagen d
205 pression variations (versus normal aorta) of transforming growth factor-beta1 (TGF-beta1), connective
208 onor corneas with interleukin-10 (IL-10) and transforming growth factor-beta1 (TGFbeta1) altered the
209 was up-regulated by the profibrotic cytokine transforming growth factor-beta1 and in PD effluent-deri
210 d investigated the interrelationship between transforming growth factor-beta1 and secreted frizzled-r
211 ponse to myelin perturbations, we identified transforming growth factor-beta1 as a partial mediator o
217 ional repressors, snail and slug, induced by transforming growth factor-beta1 or extracellular matrix
220 2 physically interacted and colocalized with transforming growth factor-beta1 through its cysteine-ri
223 ession levels of fibroblast growth factor-2, transforming growth factor-beta1, and platelet-derived g
224 tu by antagonizing E-cadherin, combined with transforming growth factor-beta1, epidermal growth facto
225 ed mesenchymal cells secreted high levels of transforming growth factor-beta1, which down-regulates m
226 ecreted frizzled-related protein 2 prevented transforming growth factor-beta1-induced atrophy in C2C1
227 tablishes a positive feedback loop enhancing transforming growth factor-beta1-mediated atrophic effec
228 rizzled-related protein 2 reduction enhances transforming growth factor-beta1-mediated effects and in
234 massing large amounts of information that is transforming how we approach cancer treatment and preven
235 abolism of ingested compounds (xenobiotics), transforming hundreds of dietary components, industrial
236 st that orbitofrontal cortex plays a role in transforming immediate prior and stimulus information in
240 kinase BCR-ABL1 in a hemopoietic stem cell, transforming it into a leukemic stem cell (LSC) that sel
244 cription-associated DNA damage might promote transforming lesions at cell type- and lineage-specific
245 ster turnaround for common genomic analyses, transforming long-running batch jobs submitted via a Lin
246 e road for new active, intelligent, or phase-transforming mechanical metamaterials bringing small-sca
249 ism works in art reception by regulating and transforming negative emotions into positive experiences
250 medial parietal cortex as a target site for transforming neural activity into control signals to com
251 nology of heterogeneous cellular states, but transforming observational studies into models of dynami
252 urvive and recover from the climate extreme, transforming once lush marshes into persistent salt barr
254 tion is an alternative to heat treatment for transforming organic-inorganic thin films to a ceramic s
255 grations within the context of their rapidly transforming Pacific Arctic ecosystem, suggesting flexib
260 YEATS mutations induced a gain of function, transforming primary hematopoietic cells in vitro and in
262 ragmentation, specifically attrition, has in transforming primary pyroclasts upon transport in volcan
263 lyl cyclase-associated protein 1 (CAP1), SHC-transforming protein 1 (SHC1) and prolylcarboxypeptidase
267 of transcription 3 through an IL-23/acutely transforming retrovirus AKT8 in rodent T-cell lymphoma/s
268 odification to next-generation sequencing is transforming RNA secondary structure studies in living c
269 rget-stimuli suggest that LIP is involved in transforming sensory information into decision-related s
270 eotide exchange factor (GEF) epithelial cell transforming sequence 2 (Ect2) has been implicated in ca
271 features as, e.g., ferroic ceramics or phase-transforming solids, and the discrete governing equation
273 cific CD8(+) T cell proliferative expansion, transforming subclinical cardiac injury to overt heart f
274 red using a previously published method of z-transforming subscales from the Memory Functioning Quest
275 ce, constructing equivalent 3D ssRNA models, transforming the 3D ssRNA models into ssDNA 3D structure
276 geneity altered the evolutionary dynamics by transforming the adaptive landscape that relates genotyp
278 ese studies unveil the possible pathways for transforming the electronic properties of MOFs from insu
279 tion of the choriocapillaris on OCTA images, transforming the images from a granular appearance to a
280 is based on determining an eigenmask filter transforming the incident optical eigenmodes to position
281 ed chronic myeloid leukemia (CML) treatment, transforming the life expectancy of patients; however th
283 -dimensional metal chalcogenide compounds by transforming the native interfacial metal oxide layer of
286 by simply adding the polar solvent, thereby transforming the polymer-iodide to polymer-N3 in one pot
287 e clinic, becoming new standards of care and transforming the prognosis for many patients with malign
288 with new chemical and physical properties is transforming the study, manipulation and evolution of pr
289 ole pairing can occur in a dilute semimetal, transforming the system into an excitonic insulator stat
290 e patients in the healthcare system but also transforming the way that we conduct clinical research.
292 ically, into the framework of DNA materials, transforming their properties in a fundamental and techn
293 ng their macroscopic organizing behavior and transforming them into new solid fibers is greatly signi
294 he synthesized compounds was demonstrated by transforming them into valuable acyclic and cyclic compo
295 and nuts) are lifelong, without any disease-transforming therapies, and unclear in their underlying
296 atom) at approximately 1440 degrees C, began transforming to alpha-SiC, with radiation-induced Frank
297 ke painful thermal TCE, an essential step in transforming transient afferent nociceptive signals into
298 that determine whether EBV enters the highly transforming type III latency, versus the more restricte
300 (2) other tissues when they are infected by transforming viruses or chronically inflamed, pointing t
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