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1 so had less re-expression of fetal genes and transforming growth factor beta1.
2 portant platelet released cytokines, such as transforming growth factor beta1.
3 talloproteinase-2, alkaline phosphatase, and transforming growth factor beta1.
4 , including bone morphogenetic protein 2 and transforming growth factor beta1.
5 and blunting of profibrogenic activities of transforming growth factor beta1.
6 al and cellular events and the activation of transforming growth factor beta1.
7 egulation of profibrotic pathway mediated by transforming growth factor-beta1.
8 of fibroblasts to the stimulatory effect of transforming growth factor-beta1.
9 n-T-helper type 1-related signals, including transforming growth factor-beta1.
10 ed upregulation of CSF-1R expression via the transforming growth factor-beta1.
11 tissue inhibitor of metalloproteinase-1, and transforming growth factor-beta1.
12 roduction of both cytokines was inhibited by transforming growth factor-beta1.
13 beta6 integrin, an activator of latent local transforming growth factor-beta1.
14 roteinase-2, matrix metalloproteinase-9, and transforming growth factor-beta1/2 and the number of Mac
16 on memory B cells, whereas interleukin-4 and transforming growth factor-beta1 act as negative regulat
19 s ability to block myostatin, activin A, and transforming growth factor-beta1, all of which are negat
20 le to undergo EMT in vitro when treated with transforming growth factor-beta1 alone or in combination
21 th factor receptor 1, 2, and 3; osteopontin; transforming growth factor beta1 and beta2; thrombospond
23 nts with SCD and isolated cytokines, such as transforming growth factor beta1 and endothelin-1, enhan
24 s in CCD-18Co fibroblasts in the presence of transforming growth factor beta1 and insulin-like growth
25 llagen, vimentin, and the fibrogenic factors transforming growth factor beta1 and insulin-like growth
26 d collagen I; this was inhibited by blocking transforming growth factor beta1 and p38 mitogen-activat
27 ed products, and decreased after blockade of transforming growth factor beta1 and p38 mitogen-activat
28 es the release of active MMP2 in response to transforming growth factor beta1 and rescues tissue inte
30 ced expression of the profibrotic mediators, transforming growth factor-beta1 and connective tissue g
32 L-6, but not IL-8, induced the expression of transforming growth factor-beta1 and elastic fiber prote
34 was up-regulated by the profibrotic cytokine transforming growth factor-beta1 and in PD effluent-deri
38 d investigated the interrelationship between transforming growth factor-beta1 and secreted frizzled-r
39 any types of carcinoma where it may activate transforming growth factor-beta1 and transforming growth
40 necrosis factor-alpha and reduced levels of transforming growth factor-beta1 and vascular endothelia
41 o enhanced (by 20% to 40%) the expression of transforming growth factors beta1 and beta2, vascular en
42 renal and glomerular hypertrophy as well as transforming growth factor-beta1) and extracellular matr
43 whereas SNAI2, vimentin, S100A4, FN1, HRAS, transforming growth factor beta1, and CD44H were high.
44 talloproteinase-9, B-cell activating factor, transforming growth factor-beta1, and elastase were high
45 cytokines IL-1beta, IL-18, interferon-gamma, transforming growth factor-beta1, and IL-4 as well as hi
46 ession levels of fibroblast growth factor-2, transforming growth factor-beta1, and platelet-derived g
47 ponse to myelin perturbations, we identified transforming growth factor-beta1 as a partial mediator o
48 gnaling pathways, including Snail, Twist and transforming growth factor-beta1 as well as the mesenchy
49 ated by tissue stiffness and the profibrotic transforming growth factor-beta1, but its role in cell f
50 pression was modulated by gut microbiota and transforming growth factor-beta1, but not by retinoic ac
52 tatin, growth differentiation factor 11, and transforming growth factor beta1, by cleaving extracellu
53 hemokine ligand 5 [CCL5]) and profibrogenic (transforming growth factor beta1, collagen type 4 alpha
54 ce, MUC5AC and matrix remodeling parameters (transforming growth factor-beta1, collagen I, and fibron
55 nd membrane-bound latency-associated peptide/transforming growth factor beta1, compared with uninfect
56 ry occlusion and were divided into 3 groups: transforming growth factor beta1-conditioned human MSC-l
58 al expression of fibrogenic genes, including transforming growth factor beta1, connective tissue grow
59 vels of key mediators of fibrosis, including transforming growth factor beta1, connective tissue grow
60 HA-binding protein TSG-6 in maintaining the transforming growth factor beta1-dependent HA coat, TSG-
61 it as a key difference between IL-1beta- and transforming growth factor beta1-dependent HA matrices.
62 sequencing (RNA-seq) analysis revealed that transforming growth factor beta1 (encoded by Tgfb1) is e
63 tu by antagonizing E-cadherin, combined with transforming growth factor-beta1, epidermal growth facto
65 hickening, podocyte foot-process fusion, and transforming growth factor-beta1 expression were amelior
66 , pancreatic duodenal homeobox-1, and active transforming growth factor-beta1 expression were increas
68 Here, we show that the expression of the transforming growth factor beta1 gene (Tgfb1) affects th
69 association with CAA of polymorphisms in the transforming growth factor beta1 gene (two studies, 449
70 tides such as alpha-smooth muscle actin, and transforming growth factor-beta1 had no effect on FGFR1O
71 LGs had higher Th-17- (interleukin [IL]-23R, transforming growth factor-beta1, IL-17A, CC chemokine a
72 We determined that genetic deficiency in transforming growth factor beta1 impairs endometriosis-l
74 ntly reduced thrombin activity and levels of transforming growth factor beta1 in BAL fluid, while sim
76 ced marked accumulation of activin A but not transforming growth factor-beta1 in conditioned media.
79 Extracellular TG2 was sufficient to activate transforming growth factor-beta1 in tubular epithelial c
80 es indicate that the upregulation of Nox4 by transforming growth factor-beta1 in ZO SMCs is responsib
82 ombination of fibroblast growth factor 2 and transforming growth factor beta1 induce profound morphol
83 In isolated adult mouse cardiac fibroblasts, transforming growth factor-beta1 induced cardiac fibrobl
84 owever, activation of AhR in the presence of transforming growth factor-beta1 induced Foxp3(+) iT(reg
85 Furthermore, tumor necrosis factor-alpha and transforming growth factor-beta1 induced the expression
87 ty of this technology to prevent and inhibit transforming growth factor beta1-induced myodifferentiat
88 ecreted frizzled-related protein 2 prevented transforming growth factor-beta1-induced atrophy in C2C1
90 ansplant model, and in the in vitro model of transforming growth factor-beta1-induced EMT in normal r
91 , Nox-2, phospho-smad2, and alpha-SMA during transforming growth factor-beta1-induced EMT of NRK52E c
92 ound that the miR-200 family members inhibit transforming growth factor-beta1-induced epithelial-mese
94 synthetic and contractile phenotype, in both transforming growth factor-beta1-induced myofibroblast d
95 fibrosis and cardiac dysfunction by blocking transforming growth factor-beta1-induced phospho-Smad2/3
101 or 1 (VEGFR1), VEGFR2, Tie2, erythropoietin, transforming growth factor beta1, insulinlike growth fac
105 nsverse aortic constriction increased active transforming growth factor-beta1 levels and phosphorylat
107 if) ligand 1; stromal cell-derived factor 1; transforming growth factor-beta1; matrix metallopeptidas
110 tablishes a positive feedback loop enhancing transforming growth factor-beta1-mediated atrophic effec
111 rizzled-related protein 2 reduction enhances transforming growth factor-beta1-mediated effects and in
112 n of a constitutively active FOXO3a overrode transforming growth factor-beta1-mediated invasive pheno
113 3), CD11b-F4/80+Gr1+ monocytes (P < 0.0001), transforming growth factor beta1 mRNA (P = 0.04), and al
114 although anti-inflammatory IL-10, IL-13, and transforming growth factor beta1 mRNA levels were not co
115 d WT mice, but Col1 alpha1, Col3 alpha1, and transforming growth factor-beta1 mRNA increased much mor
116 observed in tumor necrosis factor-alpha and transforming growth factor-beta1 mRNA levels and intrace
117 ional repressors, snail and slug, induced by transforming growth factor-beta1 or extracellular matrix
118 lasminogen activator inhibitor 1 (P=0.0002), transforming growth factor beta1 (P=0.0004), tissue inhi
120 expression levels of fibrogenic markers (eg, transforming growth factor-beta1, platelet-derived growt
122 ith previous reports, Extract PBS suppressed transforming growth factor-beta1 promoter activation in
123 Mechanistically, this process engages the transforming growth factor beta1 protein and Notch signa
124 ransforming growth factor-beta1 (TGF-beta1), transforming growth factor-beta1 receptor (TGF-beta1R),
125 Nrf2 suppressed the activity of a synthetic transforming growth factor-beta1-responsive CAGA-directe
126 ndogenous TLR4 ligands, results in augmented transforming growth factor-beta1 sensitivity with increa
127 hepatic macrophage aggregation, resulting in transforming growth factor beta1-signaled collagen depos
129 ates in a negative feedback mechanism on the transforming growth factor-beta1 signaling and downregul
130 eas the sik1(-/-) mice exhibited upregulated transforming growth factor-beta1 signaling and increased
131 arly- and late-stage cardiac remodeling with transforming growth factor-beta1 signaling at the center
133 on of the contractile phenotype of VSMCs via transforming growth factor-beta1-signaling inhibition.
134 hanistically, GSK-3beta inhibits profibrotic transforming growth factor-beta1/SMAD-3 signaling via in
136 X5 SNP-expressing cells had higher basal and transforming growth factor-beta1-stimulated expression a
137 nd interleukin 1 receptor antagonist but not transforming growth factor beta1, suggesting that alkylg
138 ce similar phenotypes, as well as of several transforming growth factor-beta1 target genes, such as m
141 models of fibrotic renal disease by opposing transforming growth factor beta1 (TGF-beta)-dependent fi
142 d that IL-17A mediates epithelial injury via transforming growth factor beta1 (TGF-beta1) and down-re
143 es of orally tolerized mice showed increased transforming growth factor beta1 (TGF-beta1) and interle
144 ves increased migration and up-regulation of transforming growth factor beta1 (TGF-beta1) and its dow
146 kophilin-2 (PKP2) in cardiomyocytes elevates transforming growth factor beta1 (TGF-beta1) and p38 mit
148 eal injury typically involves fibrosis, with transforming growth factor beta1 (TGF-beta1) as one of i
150 lower expression of the profibrogenic factor transforming growth factor beta1 (TGF-beta1) compared to
151 al immunosensor for the determination of the transforming growth factor beta1 (TGF-beta1) cytokine co
152 d activity of the immunosuppressive cytokine transforming growth factor beta1 (TGF-beta1) due to high
158 of proinflammatory mediators while restoring transforming growth factor beta1 (TGF-beta1) levels as e
159 CsA treatment and to investigate the role of transforming growth factor beta1 (TGF-beta1) on this CsA
160 rming cartilage in the presence of exogenous transforming growth factor beta1 (TGF-beta1) or with TGF
163 .5 kPa) polyacrylamide gels (with or without transforming growth factor beta1 (TGF-beta1)) and low pr
164 Addition of blocking antibodies against transforming growth factor beta1 (TGF-beta1), -2, and -3
166 by serotonin, which activates expression of transforming growth factor beta1 (TGF-beta1), a powerful
167 r messenger RNA and/or protein expression of transforming growth factor beta1 (Tgf-beta1), collagen 1
177 e increase in collagen I and III expression, transforming growth factor-beta1 (TGF- beta1) expression
178 dels of DN, and mesangial cells treated with transforming growth factor-beta1 (TGF- beta1) or high gl
179 nt memory T cells (TRM cells) require active transforming growth factor-beta1 (TGF-beta) for epiderma
180 r matrix proteins and hypertrophy induced by transforming growth factor-beta1 (TGF-beta) in renal mes
183 Racial differences in the expression of transforming growth factor-beta1 (TGF-beta1) and caveoli
184 pression of Hmga2 enhances the activation of transforming growth factor-beta1 (TGF-beta1) and Cxcl12
186 ogenic; in fact, T(H)17 cells generated with transforming growth factor-beta1 (TGF-beta1) and IL-6 pr
187 s of BM CD45(+)Col(+) cells was regulated by transforming growth factor-beta1 (TGF-beta1) and liposac
188 interactions with soluble mediators such as transforming growth factor-beta1 (TGF-beta1) and mechani
189 s, at least, partially through inhibition of transforming growth factor-beta1 (TGF-beta1) and reducti
191 in both animal models led to a reduction of transforming growth factor-beta1 (TGF-beta1) and TGF-bet
192 In the present study, we evaluate whether transforming growth factor-beta1 (TGF-beta1) and tumor n
195 which autocrine production and activation of transforming growth factor-beta1 (TGF-beta1) are require
197 ed the rate of wound closure and reduced the transforming growth factor-beta1 (TGF-beta1) expression
198 ed systemic hypertension, suppressed Agt and transforming growth factor-beta1 (TGF-beta1) gene expres
200 s inhibited by increased accumulation of the transforming growth factor-beta1 (TGF-beta1) in skeletal
201 after stimulation with the profibrotic agent transforming growth factor-beta1 (TGF-beta1) in vitro.
202 ssion correlated with impaired activation of transforming growth factor-beta1 (TGF-beta1) in vivo and
207 se PKA increased, autoinductive signaling by transforming growth factor-beta1 (TGF-beta1) initiated a
208 We investigated beta-catenin-dependent and transforming growth factor-beta1 (TGF-beta1) interaction
209 ractile protein-expressing myofibroblasts by transforming growth factor-beta1 (TGF-beta1) is a critic
214 cellular carcinoma cells and identified that transforming growth factor-beta1 (TGF-beta1) is induced
216 a concomitant increase in total circulating transforming growth factor-beta1 (TGF-beta1) levels (P =
218 to NK cell killing, which can be reversed by transforming growth factor-beta1 (TGF-beta1) neutralizin
219 his study addressed if the activation of the transforming growth factor-beta1 (TGF-beta1) pathway is,
220 P2 (S-phase kinase-associated protein 2) and transforming growth factor-beta1 (TGF-beta1) play import
222 aim of our study was to evaluate the role of transforming growth factor-beta1 (TGF-beta1) polymorphis
227 , fibroblast growth factor-2 (FGF-2), and/or transforming growth factor-beta1 (TGF-beta1) to adult bo
229 21, IL-1beta, IL-6, IL-17, IL-23, IL-10, and transforming growth factor-beta1 (TGF-beta1) were quanti
230 investigated the interaction between LOX and transforming growth factor-beta1 (TGF-beta1), a potent g
231 on of alpha-smooth muscle actin (alpha-SMA), transforming growth factor-beta1 (TGF-beta1), and matrix
232 ibrogenic phenotype through the induction of transforming growth factor-beta1 (TGF-beta1), collagen d
233 pression variations (versus normal aorta) of transforming growth factor-beta1 (TGF-beta1), connective
234 n expression of the Nrf2 pathway, as well as transforming growth factor-beta1 (TGF-beta1), fibronecti
235 astrocyte functions, we examined effects of transforming growth factor-beta1 (TGF-beta1), lipopolysa
238 lial-mesenchymal transition (EMT) induced by transforming growth factor-beta1 (TGF-beta1), papillary
239 In addition, COPD cultures released more transforming growth factor-beta1 (TGF-beta1), reflecting
240 S cells), expression of markers of fibrosis, transforming growth factor-beta1 (TGF-beta1), transformi
242 ast growth factor (FGF-2) effectively blocks transforming growth factor-beta1 (TGF-beta1)-mediated my
243 ry stiffening with ageing is associated with transforming growth factor-beta1 (TGF-beta1)-related inc
252 in adipose tissue macrophages highlights the transforming growth factor beta1 (TGFB1) gene itself as
256 d rs1982073, 'codon 10') in the 5' region of transforming growth factor-beta1 (TGFB1), a putative CF
258 sembly/absence of intercellular contacts and transforming growth factor-beta1 (TGFbeta) exposure.
262 emical inhibitor of Notch signaling and anti-transforming growth factor beta1 (TGFbeta1) antibody.
263 r effects of human polymorphisms influencing transforming growth factor beta1 (TGFbeta1) expression,
264 inhibitor of metalloproteinase-1 (TIMP1) and transforming growth factor beta1 (TGFbeta1) in activated
270 that the integrin alphavbeta8 and its latent transforming growth factor beta1 (TGFbeta1) protein liga
272 ide SLC4A2 expression under stimulation with transforming growth factor beta1 (TGFbeta1), a cytokine
273 ne human renal epithelial cells treated with transforming growth factor beta1 (TGFbeta1), a model of
274 gressive changes in renal mRNA expression of transforming growth factor beta1 (TGFbeta1), endothelin-
275 of bone morphogenetic protein 7 (BMP-7) and transforming growth factor beta1 (TGFbeta1)-induced huma
277 onor corneas with interleukin-10 (IL-10) and transforming growth factor-beta1 (TGFbeta1) altered the
280 factors (IRFs), IFN-stimulated genes (ISGs), transforming growth factor-beta1 (TGFbeta1), and several
281 and Cdc42 are the principal mediators of the transforming growth factor-beta1 (TGFbeta1)-stimulated e
283 2 physically interacted and colocalized with transforming growth factor-beta1 through its cysteine-ri
285 nd latent paracrine signaling cytokines (eg, transforming growth factor-beta1) to promote maladaptive
286 ere, we show that the profibrogenic agonist, transforming growth factor beta1, transcriptionally decr
287 ditioned medium resulted in up-regulation of transforming growth factor-beta1, transforming growth fa
288 ed transcriptional profiling of kidneys from transforming growth factor-beta1 transgenic (Tg) mice, c
289 and interferon-gamma but increased IL-2 and transforming growth factor-beta1, two cytokines required
290 s had increased expression of the cytokines, transforming growth factor-beta1, vascular endothelial g
292 egulation by endoplasmic reticulum stress or transforming growth factor-beta1, was analyzed by small
294 ses in levels of periostin, collagen VI, and transforming growth factor beta1 were linearly correlate
295 urinary cell mRNA for granzyme B, CD103, and transforming growth factor-beta1 were measured to ascert
296 f CCL2, CCL3, interleukin (IL)-6, IL-10, and transforming growth factor-beta1 were significantly elev
297 factor-alpha, hepatocyte growth factor, and transforming growth factor-beta1 were significantly lowe
299 ed mesenchymal cells secreted high levels of transforming growth factor-beta1, which down-regulates m
300 cient skin and wounds had elevated levels of transforming growth factor-beta1, which have been shown
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