ライフサイエンスコーパス: transgenic line

1 oid in the brain compared with either single transgenic line.

2 inct, brain region-specific profiles in each transgenic line.

3 s are able to generate plasmacytomas in each transgenic line.

4 te the consensus chemotype profiles for each transgenic line.

5 gainst ROS was more efficient in the TS4T8An transgenic line.

6 d only for cuticles of the severely silenced transgenic line.

7 ed to produce fewer seeds than either single transgenic line.

8 ng a novel ectoderm-specific Cre recombinase transgenic line.

9 s when exposed to light, particularly in the transgenic line.

10 n seven previously published Cre and CreERT2 transgenic lines.

11 ate compared with the other single or double-transgenic lines.

12 domesticated and wild tomato species and on transgenic lines.

13 ing the interpretation of data from affected transgenic lines.

14 beling experiments were performed in petunia transgenic lines.

15 e mutants, and an inability to create stable transgenic lines.

16 decreasing PME activity as observed in CsF3H transgenic lines.

17 se of internode GA1 to modest levels for the transgenic lines.

18 pulation of diverse GFP-labeled cells across transgenic lines.

19 bidopsis thaliana) using promoter:LUCIFERASE transgenic lines.

20 s vulnerable to degradation in overexpressed transgenic lines.

21 ase activity was reduced by about 30% in the transgenic lines.

22 plain the altered phenotypes observed in the transgenic lines.

23 has many potential applications in multiple transgenic lines.

24 cy of gene editing on extrachromosomal array transgenic lines.

25 content of up to 20% in PrCCoAOMT-deficient transgenic lines.

26 the establishment of novel, tissue-specific transgenic lines.

27 sRNA appeared to be diverse in the different transgenic lines.

28 e labeling patterns from our newly generated transgenic lines.

29 ghted the difference between the control and transgenic lines.

30 introduced gene and undesired phenotypes in transgenic lines.

31 in ectodermal tissue using two different Cre transgenic lines.

32 titative PCR and beta-glucuronidase reporter transgenic lines.

33 -selective (heat-shock) promoters in several transgenic lines.

34 We utilized a transgenic LINE-1 mouse model and tracked DNA methylatio

35 sis thaliana driven by the CaMV35S promoter (transgenic lines 35S-copC).

36 ining specific vacuole sorting determinants (transgenic lines 35S-copC-V).

37 (QK) and wild-type (Wt) backgrounds to yield transgenic lines A2QK and A2Wt, respectively.

38 These transgenic lines accumulate higher levels of spermidine

39 Instead, the transgenic lines accumulated a range of hydroxycinnamate

40 Moreover, transgenic lines accumulated the PhCHD substrate cinnamo

41 g rin, nor and Nr, and an ethylene-deficient transgenic line, ACS2-antisense.

42 UV mutagenesis of the psaA transgenic line allowed recovery of 5-FC-resistant, phot

43 We have thus generated a Xenopus laevis transgenic line allowing live imaging and conditional ab

44 ted concurrent generation and phenotyping of transgenic lines, allowing multiple lines to be assessed

45 We analyzed a YFP-COP1-expressing transgenic line and endogenous COP1 after subcellular fr

46 ertaking large-scale generation of mutant or transgenic lines and (v) new GBrowse tracks for transgen

47 ng constitutively expressing PEPR1 and PEPR2 transgenic lines and by analyzing pepr1 and pepr2 mutant

48 The transgenic lines and cis-regulatory constructs reported

49 t drought responses, we generated a range of transgenic lines and exploited the existing mutant plant

50 ete pollen control phenotype was achieved in transgenic lines and expressed stably over multiple year

51 pproaches are limited by the availability of transgenic lines and fluorescent protein combinations th

52 to drive gene expression in stable zebrafish transgenic lines and in mammalian cells.

53 formation from in-depth analysis of specific transgenic lines and independent peak identification val

54 Using specific transgenic lines and inhibitors, we determined that the

55 sive and time-consuming generation of stable transgenic lines and mutant populations - approaches lim

56 We use a combination of transgenic lines and pairwise patch recording to identif

57 Phenotypes of Populus transgenic lines and the expression of candidate shade r

58 Phloroglucinol was produced in all transgenic lines and the line with the highest PhlD tran

59 in callose deposition between the resistant transgenic lines and the susceptible wild-type plants du

60 Advancing microscopy techniques, transgenic lines and well-characterized molecular marker

61 The converse was true for the hZnT8 WT transgenic line, and dietary Zn(2+) supplementation also

62 ase transcripts were decreased in fruit from transgenic lines, and aconitase activity was reduced by

63 For 880 tagged proteins, we created transgenic lines, and for a total of 207 lines, we asses

64 Using gene ontology, transgenic lines, and in situ hybridization, we found th

65 sis thaliana) root meristem in wild-type and transgenic lines, and under selected chemical treatments

66 NtMYC2a increased leaf nicotine levels in T1 transgenic lines approximately 2.3-fold in greenhouse-gr

67 The protocol we present assumes that transgenic lines are already available, and includes pro

68 Thus, these subpallial enhancer transgenic lines are data and tool resources to study tr

69 ygen species was remarkably decreased in the transgenic lines as compared with the wild type plants.

70 lso observed in two different inducible AIL6 transgenic lines but not in 35S:ANT, suggesting that AIL

71 s decrease of anthocyanin production in some transgenic lines by down-regulating the expression of an

72 be performed in 1 d; generation of germline-transgenic lines by using this protocol takes approximat

73 rder to drive copC expression to the shoots (transgenic lines cab1-copC).

74 e with a tamoxifen-inducible Cre recombinase transgenic line, CAGGS-Cre-ER.

75 scent protein, and therefore, we generated a transgenic line carrying secreted fluorescent protein an

76 abinosylation was increased by 25% to 30% in transgenic lines carrying either of the transgenes.

77 Analysis of transgenic lines carrying of truncated versions of the A

78 Twenty-seven independent transgenic lines carrying Tnt1 insertions were generated

79 leading to greater lignin content in the Lc transgenic lines, compared to the wild type.

80 alyses with tonoplast vesicles isolated from transgenic lines confirmed that single-transgenic lines

81 Notably, field tests with near-isogenic and transgenic lines confirmed that the japonica variety car

82 With established transgenic lines, consistent results were observed with

83 2) that influences WUE in Arabidopsis, using transgenic lines contrasting in MPK12 alleles, under fou

84 ar weight distribution of the control versus transgenic lines (CTR1a, 6000; C3H4a, 5500; C3H9a, 4000;

85 pes resulting from AIL6 misexpression in the transgenic lines described here and those previously cha

86 icted enhancers analyzed in stable zebrafish transgenic lines directed expression in the larval zebra

87 The transgenic lines displayed a number of changes that rese

88 Peritoneal macrophages from transgenic lines displayed TNFR1 with elevated alpha2-6

89 We have now created barley transgenic lines downregulating the genes encoding the b

90 ustoria formation was prevented in resistant transgenic lines during both types of powdery mildew inf

91 If explants are prepared from appropriate transgenic lines, dynamic behaviors of epicardial cells

92 The epitope-tagged transgenic line eliminates the need for the self-reporti

93 While transgenic lines emitted dimethyl sulfide from leaves an

94 This BEST1-cre transgenic line enables generation of RPE-specific knock

95 ys) transformation routinely produces stable transgenic lines essential for functional genomics; howe

96 For all EGR and MASP1 mutants and transgenic lines examined, enhanced microtubule recovery

97 Metabolite profiling revealed that the transgenic lines exhausted their carbohydrates during th

98 Interestingly, PaSOD and dual transgenic lines exhibit enhanced lignin deposition in t

99 The transgenic lines exhibit unique effects in proteostasis.

100 acid composition was altered; however, these transgenic lines exhibited decreased fertility.

101 sis have been conducted using mutants and/or transgenic lines exhibiting fairly severe meiotic phenot

102 We generated a transgenic line expressing myosin with a mutation in the

103 overexpressed Arabidopsis WRI1 in seeds of a transgenic line expressing the castor fatty acid hydroxy

104 Transgenic lines expressing a controllable form of Cre r

105 iptional regulations of NRT2.1, we generated transgenic lines expressing a functional 35S::NRT2.1 tra

106 g fruit citrate levels, we analyzed fruit of transgenic lines expressing an antisense construct again

107 layed flowering were observed in Arabidopsis transgenic lines expressing an artificial miRNA target m

108 Stable transgenic lines expressing Arabidopsis thaliana Sieve-E

109 method was demonstrated by generating stable transgenic lines expressing beta-glucuronidase plus (GUS

110 isease symptoms of up to 70% was observed in transgenic lines expressing Bs2 with respect to non-tran

111 However, no transgenic lines expressing Cas9 have been developed for

112 ow its utility by generating multiple stable transgenic lines expressing fluorescent proteins under s

113 Furthermore, analysis of transgenic lines expressing full-length tomato BRI1-Flag

114 Double-transgenic lines expressing Kras(G12V) with one of the t

115 tants exhibited no overt phenotype; however, transgenic lines expressing MYC5 fused to an SRDX (SUPER

116 e generated liver-specific, Tet-on-inducible transgenic lines expressing oncogenic Kras(G12V), RhoA,

117 ed local transcript analysis with the use of transgenic lines expressing tagged NRT1.1 proteins.

118 erase chain reaction, the authors identified transgenic lines expressing transgenes somewhat higher (

119 More importantly, by generating a WAP-tva transgenic line for expression of ErbB2 selectively in W

120 o function, we made multiple stable reporter transgenic lines for each enhancer in zebrafish.

121 ent species and then screening the resultant transgenic lines for phenotypes of interest.

122 of GFP allows the use of existing GFP-tagged transgenic lines for studies of dynamic processes in liv

123 iation that enabled a global analysis of all transgenic lines from the four independent experiments.

124 rafish embryos enabled us to score 67 stable transgenic lines generated from an insertional mutagenes

125 For both transgenic lines, germline transcription of some H chain

126 l astrocytes in three mouse models of AxD, a transgenic line (GFAP(Tg)) in which the normal human GFA

127 These novel transgenic lines greatly expand the ability to monitor a

128 The hZnT8 R325W transgenic line had lower pancreatic [Zn(2+)]i and proin

129 Gor transgenic lines had up to 6 times higher GR activity an

130 infected with oncogenic A. tumefaciens C58, transgenic lines harbouring the 2S2D::p50 construct indu

131 Transgenic lines harbouring the marker fused to a gene e

132 To date, nine CreER(T2) transgenic lines have been designed using the nestin pro

133 gene expression demonstrate that zmbri1-RNAi transgenic lines have compromised BR signaling.

134 sulphonate (EMS) mutant alleles and silenced transgenic lines have valve margin defects.

135 r five photoperiods, three accessions, and a transgenic line, highlighting the plasticity of plant gr

136 anial vasculature, we generated an etsrp:GFP transgenic line in which GFP reporter is expressed under

137 FR failed to depress PDF1.2 mRNA levels in a transgenic line in which PDF1.2 transcription was up-reg

138 ganglion cells in the mouse retina, using a transgenic line in which these cells, called "W3", are l

139 ation in A. gambiae, resulting in homozygous transgenic lines in approximately 2-3 months.

140 lycine showed significant changes across all transgenic lines in comparison to wild-type plants.

141 Here, we use new fluorescent transgenic lines in the beetle Tribolium castaneum to sh

142 More extensive phenotyping of transgenic lines in the greenhouse may contribute to imp

143 d lines showed improved growth, whereas only transgenic lines in the wild-type background showed incr

144 dent copy number measurements in independent transgenic lines in these crop species.

145 by establishing two additional sets of mouse transgenic lines in which DNA segments containing these

146 GI in the flowering pathway, we established transgenic lines in which GI is expressed exclusively in

147 axonal and dendritic arbors using four mouse transgenic lines in which nonoverlapping subsets of RGCs

148 imed at improving our support for mutant and transgenic lines, including (i) enhanced mutant/transgen

149 tion of H-type lignin in PrCCoAOMT-deficient transgenic lines increased, resulting in up to a 10-fold

150 ype tomato fruits and, when overexpressed in transgenic lines, increased plastid number, area, and pi

151 tional allele Chm(Flox) was crossed with the transgenic line IRBP-Cre to achieve Chm KO, specifically

152 tion events from a population of independent transgenic lines is desirable.

153 Although several transgenic lines label neural crest subpopulations, few

154 readily reduced the H monomer content of the transgenic lines, leaving a residual lignin greatly enri

155 s of Pompe disease--the Gaa(-/-) mouse and a transgenic line (MTP) expressing GAA only in skeletal mu

156 these problems, we have adopted the use of a transgenic line of Arabidopsis (Arabidopsis thaliana) wh

157 ll line that was initiated from ovaries of a transgenic line of fish [Tg(gsdf:neo)] that expresses Ne

158 m cell (FGSC) cultures were generated from a transgenic line of fish that expresses Neo and DsRed und

159 In this work, we generated a transgenic line of zebrafish expressing a photoconvertib

160 In the present study, a transgenic line of zebrafish had been generated using a

161 We developed a transgenic line of zebrafish that expresses a red fluore

162 -system of binary gene expression to develop transgenic lines of Anopheles gambiae in which olfactory

163 n vivo context, we generated multiple stable transgenic lines of Arabidopsis (Arabidopsis thaliana) t

164 erformed genetic complementation analyses of transgenic lines of bacterial artificial chromosomes of

165 The transgenic lines of F5H-amiRNA and C3H-amiRNA showed a r

166 filin1 in motor neuron disease, we generated transgenic lines of mice expressing human profilin1 with

167 LAMB2 cause proteinuria, we generated three transgenic lines of mice in which R246Q-mutant rat lamin

168 zation of Q-satRNA was completely blocked in transgenic lines of Nicotiana benthamiana (ph5.2nb) that

169 ns to green fluorescent protein expressed in transgenic lines of rice (Oryza sativa).

170 Stable overexpression transgenic lines of TX and TN genes in Arabidopsis produ

171 New animal models such as transgenic lines of zebrafish, which are near transparen

172 s in the context of nociception, using novel transgenic lines, optogenetics, and calcium imaging in b

173 nes (Os07g37920-RNAi) and 10 over-expressing transgenic lines (Os07g37920-OE), but none of them showe

174 scent protein (GFP) reporter to generate the transgenic line OS521Oct-4p.

175 ll usually be advantageous when creating new transgenic lines, our method for photoconversion of GFP

176 These transgenic lines outperform control plants when challeng

177 regulated by BZR1 in two independent tomato transgenic lines over-expressing BZR1-1D at four ripenin

178 his study, Arabidopsis wild-type (Col-0) and transgenic lines overexpressing PIP2;7 were used to inve

179 reduced in the rgl3-5 mutant and enhanced in transgenic lines overexpressing RGL3.

180 ith high-chill kiwifruit Actinidia deliciosa transgenic lines overexpressing SVP2 showing suppressed

181 Analysis of the transcriptome of transgenic lines overexpressing the tomato APPR2-Like ge

182 The ubi promoter and the transgenic lines presented here thus provide a broad res

183 Among the transgenic lines produced, only Tg(RBD2/3*-HA)::RPE-cre:

184 thaliana) seeds 13 d post anthesis of three transgenic lines, producing varying levels of recombinan

185 This TDP-43 transgenic line provides a valuable tool for identifying

186 m2(-/-) (T2(-/-)) mice to the PS19 human tau transgenic line (PS) to investigate whether loss of TREM

187 sinus epithelium, we generated a conditional transgenic line, R26hAR(loxP):Osr1-Cre+.

188 scently tagged PIP2;7 in TSPO-overexpressing transgenic lines resulted in patchy distribution of the

189 The truncation in both transgenic lines results in deletion of the 3'-most enha

190 similar period, using a heat-shock inducible transgenic line, results in the loss of posterior otic s

191 f retroviral bone marrow chimaeras and a TCR transgenic line revealed that microbiota indigenous to o

192 Molecular analysis of transgenic lines revealed stable integration of transgen

193 Molecular analysis of these transgenic lines revealed that Fv SOC1 activates Fv TFL1

194 Transgenic line rNAD-ME1 had 8%, and rPPDK1 had 5% of th

195 s) from B. braunii into wild-type plants and transgenic lines selected for high-level triterpene accu

196 The best peptide transgenic line showed improved agronomic performance re

197 While the PfRh2b deletion transgenic line showed no change in invasion pathway uti

198 MtROP9i transgenic lines showed a clear growth-reduced phenotype

199 Compared to wild-type Col-0, all transgenic lines showed a significant increase in the co

200 The doubly transgenic lines showed a three-fold enhancement of isop

201 Transgenic lines showed delayed senescence and enhanced

202 * At the cellular level, all transgenic lines showed increased tolerance to arsenite

203 These transgenic lines showed no biomass penalty despite a 10%

204 pared to wild type plants, whereas RNAi:ERD4 transgenic lines showed reduced leaf number, leaf area,

205 The overexpressing transgenic lines showed significant increase in number o

206 Analysis of transgenic lines showed that CESA7 can partially rescue

207 Live imaging of these transgenic lines showed that Cftr is localized to the ap

208 Transgenic lines showed that they are more vulnerable to

209 Genome-wide expression analysis using transgenic lines suggested that miR858a targets a number

210 sed excision during late development in most transgenic lines, suggesting that transposition is devel

211 Four homozygous transgenic lines (T4) expressing the mutant 1Ax1 gene (m

212 stem, we generated eight tet-regulated shRNA transgenic lines targeting Firefly and Renilla luciferas

213 we show that heat-shock induction of a novel transgenic line, Tg(hsp70l:nkx2.5-EGFP), during the init

214 ere we report the development of a zebrafish transgenic line, Tg(igfbp5a:GFP), which faithfully repor

215 sed nearly 200% more fermentable sugars from transgenic lines than controls, which were not explained

216 evel of lignin associated pyrolysates in the transgenic lines than the control primarily when the enz

217 more continuous gluten matrix in the mutant transgenic lines than the one line mentioned-above.

218 one or both of the xanthophylls as well as a transgenic line that accumulates lutein via an engineere

219 To visualize memory traces, we created a transgenic line that allows for the comparison between c

220 y crossing myd animals to a recently created transgenic line that expresses LARGE selectively in diff

221 Using a novel transgenic line that labels the endodermal actin cytoske

222 Through the use of a transgenic line that misexpresses cdc25a, we show that t

223 Transgenic lines that constitutively overexpress BOA exh

224 To address these issues we generated transgenic lines that constitutively overexpressed a tru

225 irectly correlates with stress resistance in transgenic lines that ectopically express APT1.

226 Cre-mediated gene manipulation using transgenic lines that express Cre under the control of t

227 Transgenic lines that express forms of a conserved mamma

228 e amelogenin (AmelX) promoter and identified transgenic lines that express virtually no transgene, sl

229 We established and analyzed 5 transgenic lines that expressed ameloblastin from the am

230 We tested this hypothesis by creating two transgenic lines that expressed the E. coli nitroreducta

231 NG OF CAB EXPRESSION1 (TOC1), was altered in transgenic lines that overexpress BOA.

232 ing region retains hepatic competence: using transgenic lines that overexpress hepatic inducing signa

233 Transgenic lines that produced heritable mPing insertion

234 nhancer-trap recombinase, Flippase (ET-FLP), transgenic lines that provide inheritable, reproducible,

235 eek such differences, we characterized mouse transgenic lines that selectively mark ooDSGCs preferrin

236 Passage of transgenic lines through two different tissue culture tr

237 To investigate this, we created a transgenic line to ablate the epicardial cell population

238 recombination activating gene (Rag)2:mCherry transgenic line to identify B cell development stages in

239 e and female mice of a doxycycline-inducible transgenic line to induce expression of constitutively a

240 c neurons demonstrate the usefulness of this transgenic line to study novel roles of Nav1.8 beyond se

241 Here, we use transgenic lines to define the in vivo relevance of HDAC

242 , and overall fertility were analyzed in the transgenic lines to evaluate the requirement of each exo

243 We used expression profiling and mouse transgenic lines to identify and characterize two closel

244 99.5% of the progeny following outcrosses of transgenic lines to wild-type mosquitoes.

245 from transgenic lines confirmed that single-transgenic lines TVP1cl19 and TNHXS1cl7 had greater H(+)

246 5 in melanoma formation, we generated mGluR5 transgenic lines under a melanocyte-specific promoter, t

247 Growing the transgenic lines under different nitrogen regimes indica

248 such improvement was observed for the SeCspB transgenic lines under field conditions.

249 f the toxic metabolite, methylglyoxal in the transgenic lines under non-stress and stress (drought an

250 Transgenic lines underproducing abscisic acid, with lowe

251 We generated two transgenic lines using the Xenopus rhodopsin promoter to

252 ESSOR1-yellow fluorescent protein (BES1-YFP) transgenic line was developed that showed BR-inducible B

253 th the brown and milled rice grains from the transgenic line was substantially equivalent to that of

254 tritional value and/or energy density of the transgenic lines was increased by ectopic expression of

255 Using an antisense GEX1 transgenic line we demonstrate that the predicted GEX1 e

256 Using a P0-inducible transgenic line, we observed that AGO1 degradation is bl

257 with a Cdh2 tandem fluorescent protein timer transgenic line, we observed that Cdh2-EGFP molecules ap

258 In both transgenic lines, we found fewer proprioceptive sensory

259 Here, using lacZ reporter activity in transgenic lines, we have characterized three cis-regula

260 By characterizing these transgenic lines, we showed that agrp1-expressing neuron

261 e both oil yield and composition in a single transgenic line were assessed as well.

262 acts from microsomal membranes prepared from transgenic lines were able to fucosylate, in vitro, puri

263 Elite transgenic lines were advanced to multiyear field trials

264 Transgenic lines were analyzed for the production of PG

265 For each construct, five independent transgenic lines were characterized phenotypically and g

266 elopmental defects in the highest expressing transgenic lines were consistent with the inhibition of

267 Phenotypically strong and weak transgenic lines were examined and shown to correlate wi

268 0 or 200 mM) treated PDH45 overexpressing T1 transgenic lines were lower as compared to wild type (WT

269 CD79 transgenic lines were made by linking the promoter and u

270 In addition, tt16 RNAi transgenic lines were more sensitive to auxin.

271 used in the plasmid construction, but seven transgenic lines were obtained with a genetic constructi

272 nd disulfide groups in gluten of the mut1Ax1 transgenic lines were significantly increased.

273 oter were isolated, and mct8 promoter-driven transgenic lines were used to show that, similar to huma

274 ficantly in the peel of both the control and transgenic lines when exposed to light, particularly in

275 Our results showed that transgenic lines, when exposed to Ag NPs and Ag(+) ions,

276 e motor learning enhancements as the soluble transgenic lines, whereas previously, aged lynx1KO mice

277 rvae) without the need to establish germline transgenic lines (which take 12-18 months).

278 MP signaling in HSC ontogeny, we have used a transgenic line, which inducibly expresses an inhibitor

279 was unaffected in the cones of the XOPS-mCFP transgenic line, which lacks rod photoreceptors.

280 functional roles of the sites in vivo, three transgenic lines, which expressed cMyBP-C containing eit

281 quitous and tissue-specific luciferase-based transgenic lines, which we have termed zebraflash, that

282 In transgenic lines, which were generated using the ortholo

283 We generated a transgenic line whose macrophages expressing tumour necr

284 This transgenic line will facilitate high-throughput genetic

285 ings suggest that mhc2dab:GFP and cd45:DsRed transgenic lines will be instrumental in elucidating the

286 In this study, we crossed a Pina-expressing transgenic line with a 1Ax1-expressing line of durum whe

287 Here we use a transgenic line with a green fluorescent protein (GFP) e

288 Using CRISPR/Cas9, we created a transgenic line with a homozygous deletion of TpnC41C an

289 onic stem (ES) cells to generate a novel NOD transgenic line with the 77A/G SNP.

290 The gene-edited Dd2 transgenic line with the A578S mutation, which expresses

291 gamma2a genes is at wild type levels for the transgenic line with the larger truncation, but at reduc

292 er truncation, but at reduced levels for the transgenic line with the smaller truncation.

293 Transgenic lines with altered PHYB1 and/or PHYB2 express

294 milar to levels in ham1ham2 RNA interference transgenic lines with decreased expression of acetyltran

295 We generated transient and stable transgenic lines with just the R2 element or the entire

296 sion analysis following high-light stress in transgenic lines with perturbed AtWRKY40 and AtWRKY63 fu

297 Tobacco (Nicotiana tabacum) transgenic lines with reduced levels of ASR protein show

298 Arabidopsis RNAi transgenic lines with reduced mtPPT expression display t

299 In this study, we generated transgenic lines with simultaneous nfc101 and nfc102 dow

300 e analyzed iNKT cell development in CD3 zeta transgenic lines with various tyrosine-to-phenylalanine