ライフサイエンスコーパス: transgenic mice

1 mitochondrial and synaptic toxicities in APP transgenic mice.

2 cking Slco1a/1b isoforms), and human OATP1B1-transgenic mice.

3 optive transfer in immunodeficient human TPO-transgenic mice.

4 n, aberrant crypt formation and polyposis in transgenic mice.

5 axon degeneration in zebrafish larvae and in transgenic mice.

6 ecies of seed-competent Tau in the brains of transgenic mice.

7 functions are differentially affected in the transgenic mice.

8 fected IFN-alpha/beta receptor-deficient HLA transgenic mice.

9 ticulum stress in the prostate glands of ERG transgenic mice.

10 phenotypes observed in the gain-of-function transgenic mice.

11 f dopaminergic cell death in alpha-synuclein transgenic mice.

12 in-2 to the central nervous system of TDP-43 transgenic mice.

13 g genetically targeted Channelrhodopsin 2 in transgenic mice.

14 ognitive functions of APP/presenilin-1 (PS1) transgenic mice.

15 ng Alb-TSC1(-/-) (AT) and Alb-mTOR(-/-) (Am) transgenic mice.

16 kout mice with TDP-43 (also known as TARDBP) transgenic mice.

17 in transient activation of endogenous CTL in transgenic mice.

18 confer resistance to disease in HLA-DR15/DR1 transgenic mice.

19 on of human HO-1 in MHC class II(+) cells in transgenic mice.

20 revents brain atrophy and memory loss in p25-transgenic mice.

21 ficantly decreased fecundity of Dppa3 (R60A) transgenic mice.

22 different IgG isotypes of 1F5 in human CD27-transgenic mice.

23 g protein expression was not up-regulated in transgenic mice.

24 2 were decreased in jejunal tissue in septic transgenic mice.

25 e complexes and induced CD8(+) T cells in A2-transgenic mice.

26 recallable CTL memory response developed in transgenic mice.

27 As an example, we apply qMotor to SOD1(G93A) transgenic mice.

28 ressor cells (MDSCs) to the liver of HLA-DR4 transgenic mice.

29 ene dosage-dependent and are >1 muM in apoA1 transgenic mice.

30 a (MCAT) and in cartilage explants from MCAT transgenic mice.

31 ng activity that was specific for HCC in HBx transgenic mice.

32 B rescued the neurodegeneration in alpha-syn transgenic mice.

33 out [cKO]) when crossed with Cre recombinase transgenic mice.

34 -like particles in human immunoglobulin loci transgenic mice.

35 ed or estrogen-treated nontransgenic and HPV-transgenic mice.

36 kedly reduced in mammary epithelial cells of transgenic mice.

37 agy in living tissues obtained from mt-Keima transgenic mice.

38 erified in both HSP70-1 knockout and HSP70-1 transgenic mice.

39 yte maturation and regeneration processes in transgenic mice.

40 amine levels without damaging neurons in non-transgenic mice.

41 38093 treatment on 7-month-old APPSWE Tg2576 transgenic mice, a model of Alzheimer's disease, were al

42 tive airway epithelial cells was observed in transgenic mice after LPS stimulation.

43 at insulin promoter-membrane-bound ovalbumin transgenic mice after sham or IRI procedures.

44 study, we show that hepatocyte-specific SND1 transgenic mice (Alb/SND1 mice) develop spontaneous HCC

45 ase and, in alpha3135-145-immunized HLA-DR15 transgenic mice, alpha3135-145-specific T cells infiltra

46 Importantly, alpha2KD+Rac1 mKO double-transgenic mice also displayed severely impaired contrac

47 mias developed in Pml(C62A/C65A) mice, these transgenic mice also expressing RARalpha linked to a dim

48 The abundance of ILC2s in Id1 transgenic mice also offers a unique opportunity for tes

49 ession analysis of amyloid precursor protein transgenic mice also revealed high level of mmu-miR-455-

50 In vivo sudemycin treatment of U2AF1(S34F) transgenic mice alters splicing and reverts haematopoiet

51 postmortem brains, amyloid precursor protein transgenic mice and AD cell lines.

52 4D inhibitor is able to enhance memory in AD transgenic mice and concomitantly rescues their hippocam

53 yed the Gdf5 locus for regulatory regions in transgenic mice and fine-mapped separate enhancers contr

54 mine in heart failure post-MI using HDC-EGFP transgenic mice and HDC-knockout (HDC(-/-)) mice.

55 Furthermore, iMGLs transplanted into transgenic mice and human brain organoids resemble micro

56 irus into the NAc of (anti-GFP) nanobody-L10 transgenic mice and immunoprecipitated translating ribos

57 ria in motor neurons isolated from SOD1 G93A transgenic mice and in ALS mutant SOD1 transfected corti

58 n neuroblastoma growth in TH-MYCN homozygous transgenic mice and MYCN gene-amplified neuroblastoma xe

59 complex stability, and immunogenicity in A2-transgenic mice and on peripheral blood mononuclear cell

60 turated fatty acids (PUFAs), by use of fat-1 transgenic mice and oral administration of fish oil, sig

61 To address this question, here we combined transgenic mice and pharmacological tools to specificall

62 tion was performed on brain extract from tau-transgenic mice and postmortem AD brain and added to a s

63 cells in TG of latently infected HLA-A*0201-transgenic mice and reduced recurrent ocular herpes foll

64 In Alzheimer amyloid precursor protein-transgenic mice and SH-SY5Y cell models, we specifically

65 -) mice, cardiac myocyte-specific iPLA2gamma transgenic mice, and wild-type mice.

66 Furthermore, compared with wild-type mice, transgenic mice (aP2-MRAP) overexpressing MRAP fat speci

67 ic activity regulation, suggesting that CREM transgenic mice are a valuable experimental model for hu

68 ker of embryonic dSPNs and the Sox8-EGFP BAC transgenic mice are an excellent tool to study the devel

69 o the species-specificity of renin activity, transgenic mice are ideal models for experimentally inve

70 sponses to LPS and bacterial infection, POP2 transgenic mice are more resistant to bacterial infectio

71 c T cells in C57BL/6 mice as the majority of transgenic mice are only available on this background.

72 ramer(+) T cells in HLA-DR1 and HLA-DR15/DR1 transgenic mice are predominantly CD4(+)Foxp3(+) regulat

73 lammation in amyloid precursor protein (APP) transgenic mice are worsened by astroglial NF-kappaB hyp

74 regates observed in the motor neurons of the transgenic mice as early as 1 mo of age.

75 ith progenitor properties is elevated in the transgenic mice at the lactation stage, suggesting inhib

76 i67-positive mammary epithelial cells in the transgenic mice at the lactation stage.

77 f p25/Cdk5 in tauopathy, we generated double-transgenic mice by crossing mice overexpressing mutant h

78 brosis by SHP2-lentiviral administration and transgenic mice carrying a constitutively active SHP2 mu

79 (hAS) on blood pressure (BP), we established transgenic mice carrying the hAS gene (cyp11B2).

80 uences of this missense mutation, we created transgenic mice carrying this mutation by introducing th

81 out our studies using 4 to 5 week old triple transgenic mice (Col1a1XCol2a1XCol10a1).

82 sion in the cervical microenvironment of HPV-transgenic mice compared with nontransgenic mice.

83 its seeding activity in the brain of double transgenic mice compared with the P301S mice.

84 imilar methylation dynamics were observed in transgenic mice containing a human insulin promoter frag

85 In cultured cells and in transgenic mice, deficiency in endothelial autophagy was

86 In transgenic mice deficient for exon 1b, PV interneurons l

87 phenocopied the microbicidal defect because transgenic mice demonstrated impaired clearance of pulmo

88 ntium burden in claudin-2-deficient, but not transgenic, mice, demonstrating that claudin-2-mediated

89 all, this study indicates that TDP-43(A315T) transgenic mice develop key features resembling key aspe

90 Consistent with these observations, hCD22 transgenic mice develop normal humoral responses in a pe

91 Indeed, with age, Emicro-bcl-b transgenic mice develop the characteristic features of h

92 med in parabiotic pairs of COL-EGFP mice and transgenic mice developing autochthonous intestinal aden

93 When fed a high-fat diet (HFD), the transgenic mice displayed a significant decrease in the

94 However, these transgenic mice displayed normal social approach, social

95 Transgenic mice displayed progressive impairments in acq

96 this study, deletion of Ptpro in MMTV-Erbb2 transgenic mice dramatically shortened the mammary tumor

97 nt Protein (CpepSfGFP) has been expressed in transgenic mice, driven by the Ins1 promoter.

98 nd nonproductive Ig gene rearrangements from transgenic mice engineered to express single copies of t

99 lpha3135-145 tetramer(+) T cells in HLA-DR15 transgenic mice exhibit a conventional T-cell phenotype

100 e demonstrate that endothelial-specific Nox4 transgenic mice exhibit a hypo-contractile phenotype in

101 her a T independent or T dependent Ag, TLR10 transgenic mice exhibit diminished Ab responses.

102 Upon exposure to UVB irradiation, fat-1 transgenic mice exhibited a significantly reduced epider

103 Furthermore, aged miR-32 transgenic mice exhibited metaplasia-associated prostati

104 TgCRND8 (Tg) transgenic mice express human amyloid precursor protein

105 C19MC transgenic mice expressed a low level of C19MC miRNAs in

106 nonproductive human VH rearrangements in the transgenic mice expressed shorter CDRH3 with less N addi

107 ens stent peritonitis myocytes isolated from transgenic mice expressing a calcium and calmodulin-depe

108 Transgenic mice expressing a dominant-negative Orai1 mut

109 SOD1 was assayed in spinal cord extracts of transgenic mice expressing a G85R SOD1-yellow fluorescen

110 We generated transgenic mice expressing an alpha1C with alanine subst

111 jected C3a receptor-deficient mice, GFAP-C3a transgenic mice expressing biologically active C3a in th

112 Here we developed transgenic mice expressing CGG repeat RNA with or withou

113 hesis that enhanced cardiomyocyte renewal in transgenic mice expressing cyclin D2 would be beneficial

114 Therefore, we used male and female transgenic mice expressing EGFP under the control of the

115 investigate this problem, we have generated transgenic mice expressing either the ALS-associated mut

116 We report that transgenic mice expressing endogenous levels of mutant C

117 al changes were tracked longitudinally using transgenic mice expressing fluorescent proteins localize

118 dy was found in brain cells from MAPT mutant transgenic mice expressing FTLD mutant human MAPT.

119 distinct astrocyte subtypes were found using transgenic mice expressing GFP and MrgA1 receptors in as

120 Transgenic mice expressing hCD55 alone were protected ag

121 d presentation of ocular neo-self-antigen in transgenic mice expressing hen egg lysozyme (HEL) under

122 Here we show that transgenic mice expressing HIV-1 envelope glycoprotein 1

123 on of bone marrow (BM)-derived stem cells in transgenic mice expressing human AATZ (the Z variant of

124 o study the pathophysiology of AD, including transgenic mice expressing human amyloid-beta precursor

125 e present study, we found that livers of PiZ transgenic mice expressing human ATZ have altered expres

126 6(-/-) and Enpp1(asj) mice were crossed with transgenic mice expressing human ENPP1, an ectonucleotid

127 homogenates containing IAPP aggregates into transgenic mice expressing human IAPP dramatically accel

128 n the intestinal tumorigenesis, we generated transgenic mice expressing IL-33 in intestinal epithelia

129 Transgenic mice expressing inhibitory complexes for miR-

130 uorescence recovery after photobleaching and transgenic mice expressing labeled PSD-95, we comparativ

131 Here we generated cardiac-specific transgenic mice expressing Mg29 to model this observed i

132 Transgenic mice expressing miR-471-5p in Sertoli cells s

133 avascularly, or overproduced in the brain of transgenic mice expressing mutated forms of the amyloid

134 We also generated transgenic mice expressing RDH10 ectopically in rod cell

135 Conditional knockout mice and transgenic mice expressing recombinases, reporters, and

136 marrow transplantation (BMT) experiments in transgenic mice expressing single mutations in the Cx3cr

137 Using transgenic mice expressing the fluorescence resonance en

138 as to unravel these mechanisms using FL-N/35 transgenic mice expressing the full HCV ORF.

139 We investigated hepatic steatosis in transgenic mice expressing the HIV-1 accessory protein V

140 development of CNS autoimmunity in humanized transgenic mice expressing the MS-associated MHC class I

141 Transgenic mice expressing the Notch-4 intracellular dom

142 s undergoing differentiation into oocytes in transgenic mice expressing the suicide gene, herpes simp

143 Eosinophils from the spleens of IL-5 transgenic mice, fluorescently labeled ex vivo, were int

144 s studies of CNS neuroinvasion in M83 alphaS transgenic mice following hind limb muscle (intramuscula

145 Transgenic mice generated by random genomic insertion ap

146 For transgenic mice generation, the human scavenger receptor

147 e current study, a fortuitous observation in transgenic mice globally overexpressing heparanase (hep-

148 s and neutrophils, ischemic hemispheres from transgenic mice had less infiltration (n=4).

149 ir potential roles, sperm from wild type and transgenic mice harboring a single copy insert of the hu

150 and photocarcinogenesis using hairless fat-1 transgenic mice harboring omega-3 desaturase gene capabl

151 m treatment prevents cardiomyopathy in vivo, transgenic mice harboring the R92Q troponin-T mutation a

152 However, these transgenic mice have relatively little CAA.

153 ular investigation; and targeted replacement transgenic mice homozygous for APOE epsilon4.

154 ed specific binding to PDE5 in myocardium of transgenic mice; however [(18)F]-17 showed significantly

155 Employing hRetn-expressing transgenic mice (hRETNTg(+)) and recombinant hRetn, we i

156 We applied qMotor in SOD1(G93A) transgenic mice in an inbred C57BL/6J background, hereaf

157 itochondria from 6-12 week old wild-type and transgenic mice in the absence of disease.

158 of the distal aqueous drainage tract (DT) in transgenic mice in vivo and ex vivo; (b) criteria for di

159 e to the Asp(1) site both in male and female transgenic mice in vivo and in cell lines and primary ne

160 By using Pou4f3/eGFP-transgenic mice in which HCs express GFP driven by Pou4f

161 Transgenic mice in which Ser367 of PS1 was mutated to Al

162 Transgenic mice in which Tcf7l2 was selectively inactiva

163 infected human leukocyte antigen DR2 and DR3 transgenic mice, indicating potential relevance in human

164 typed rabies virus in tumor virus A receptor transgenic mice, indicating that resistance to retrograd

165 dy, we use organotypic cultures derived from transgenic mice inducibly expressing oncogenic beta-cate

166 Moreover, a reduction in progranulin in tau transgenic mice is associated with increasing tau accumu

167 ical approaches in ex vivo brain slices from transgenic mice, it was found that 2 weeks of haloperido

168 In this article, we report that transgenic mice lacking Cfh alleles exhibit delayed peri

169 Consequently, soluble gp130 fused to Fc transgenic mice lacking IL-6 trans-signaling are largely

170 Chronic administration of ponezumab to transgenic mice led to a significant reduction in amyloi

171 ouse embryonic fibroblasts prepared from the transgenic mice led to aberrant mitosis followed by aneu

172 We have previously shown in several AD transgenic mice lines that blocking the apoE/Abeta inter

173 r cells, mouse MAIT hybridoma lines, HLA-DR4-transgenic mice, MAIThighHLA-DR4+ bone marrow chimeras,

174 assembly in a diabetes-associated phenotype transgenic mice model.

175 Using transgenic mice models and human clinical samples, we de

176 effect was assessed by survival of beta-ENaC-transgenic mice, mucus transport in these mice, and mucu

177 Furthermore, hCD22 transgenic mice on an mCD22(-/-) background have restore

178 By generating P301S tau transgenic mice on either a human ApoE knock-in (KI) or

179 acerbated AD-like pathology compared with AD transgenic mice or AD transgenic animals with type 1 dia

180 Transgenic mice over-expressing rabbit calpastatin (Calp

181 Here we show that clinically ill transgenic mice overexpressing hamster prion protein (Tg

182 intraperitoneal glucose tolerance testing in transgenic mice overexpressing hZnT8 WT or hZnT8 R325W f

183 We observed that transgenic mice overexpressing in neurons a human APP ge

184 By contrast, loss-of-function transgenic mice overexpressing microRNA decoys for eithe

185 the effects of miR-32 in vivo, we developed transgenic mice overexpressing miR-32 in the prostate.

186 Hearts from transgenic mice overexpressing SNRK have decreased gluco

187 Here we show that hamster prion-infected transgenic mice overexpressing the hamster prion protein

188 Here we report that transgenic mice overexpressing the human COMT-Val gene (

189 Transgenic mice overexpressing Ube3a isoform 2 in excita

190 glucagon-like peptide-1 agonist exendin-4 in transgenic mice paves the way for translating this innov

191 ired glucose-stimulated insulin secretion of transgenic mice, pointing to a potential mechanism throu

192 cle of yellow fluorescent protein-expressing transgenic mice produced a 17 +/- 1% loss of dendritic s

193 The neuronal overexpression of LOTUS in transgenic mice promotes motor recovery after SCI, and r

194 events leading to a prediabetic state in HCV-transgenic mice, providing a valuable mechanistic explan

195 oa1bp(-/-) mice by crossing them with apoA-I transgenic mice rescued Notch activation and corrected d

196 lline for 2-wk to 14-mo-old proaggregant Tau transgenic mice restores the spatial memory deficits and

197 , crossing the W131A mutant mice to OTII TCR transgenic mice resulted in increased negative selection

198 reatic IAPP aggregates into the brains of AD transgenic mice resulted in more severe AD pathology and

199 on of CR3 in human amyloid precursor protein-transgenic mice results in decreased, rather than increa

200 non-senescent B-cell lymphomas from Emu-Myc transgenic mice revealed substantial upregulation of an

201 In transgenic mice selectively over-expressing PGC1beta in

202 arance of apoptotic germ cells as miR-471-5p transgenic mice show lower levels of Dock180, LC3, Atg12

203 hat occurs in disease, cardiac-specific BEX1 transgenic mice show worse cardiac disease with stress s

204 Double-transgenic mice showed 55% double labeling of periurethr

205 Immunized transgenic mice showed an increase in hIAPP-antibody ser

206 Transgenic mice showed less neurological deficit compare

207 Transgenic mice showed significant deficits in a hippoca

208 In B6.Sle2(z)HEL(Ig).sHEL BCR-transgenic mice, Sle2(z) did not breach central toleranc

209 in the embryonic striatum and Sox8-EGFP BAC transgenic mice specifically reveal the direct pathway a

210 ent alterations were not present in juvenile transgenic mice, suggesting a developmental trajectory t

211 e inhibitory CREM isoform CREM-IbDeltaC-X in transgenic mice (TG) leads to spontaneous-onset AF prece

212 in human virus isolates was more virulent in transgenic mice than parental virus, demonstrating that

213 series of green fluorescent protein reporter transgenic mice that display stage-specific activation o

214 This phenotype is similar to that of transgenic mice that express amyloid precursor protein (

215 Using transgenic mice that express EGFP in response to activat

216 p recording in spinal cord slices from adult transgenic mice that express enhanced green fluorescent

217 r the intravital imaging of mammary cells in transgenic mice that express fluorescently tagged marker

218 mmune encephalomyelitis (EAE) was induced in transgenic mice that express human CD20 on B cells.

219 sed Irf6 heterozygous ( Irf6(+/-)) mice with transgenic mice that express Spry4 in the basal epitheli

220 measure NF-kappaB activity we used a line of transgenic mice that express the LacZ gene under the con

221 In contrast, transgenic mice that expressed KCP in the kidney, liver,

222 ction selectivity is dramatically reduced in transgenic mice that have decreased retinal selectivity.

223 eviously, we observed PCG-like phenotypes in transgenic mice that lack functional angiopoietin-TEK si

224 ctivity from the anterior dorsal thalamus in transgenic mice that lack functional horizontal semicirc

225 We found that in transgenic mice that overexpress hamster PrP(C), PrP(C)

226 Finally, transgenic mice that overexpress human TRX80 specificall

227 er phosphorylation sites on IRS2 function in transgenic mice that overexpress, selectively in pancrea

228 Furthermore, transgenic mice that overexpressed monomeric sP-selectin

229 from the structural gene and demonstrated in transgenic mice that Tce1 promoted T lymphocyte-specific

230 e demonstrated with chicken OVA-specific TCR-transgenic mice that the same tolerizing protocol (CD4 b

231 e apparatus has been studied in vitro and in transgenic mice, the contractile defect in human heart m

232 mparable among NT, hWT, and hMT mice.In DYT1 transgenic mice, the inverse changes of PDE10A in striat

233 fects of seeded alphaS aggregation in alphaS transgenic mice through intracerebral or peripheral inje

234 , we used fixed TRAV8-1/TRAJ9 TCRalpha-chain transgenic mice to assess the impact of PI isoform expre

235 We used Cre/loxP transgenic mice to conditionally target InsRs in fetally

236 The peptide increases survival of beta-ENaC-transgenic mice to greater than 90% with once-daily dosi

237 We used transgenic mice to modify glial activity and found that

238 Here, we used DcxCreER(T2) transgenic mice to permanently pulse-label age-defined c

239 specific knock-out mouse by crossing OMP-Cre transgenic mice to Ric-8b floxed mice.

240 ance in multiple system atrophy patients and transgenic mice together with the beneficial effects of

241 ated ATXN3 species in flies and in brains of transgenic mice treated for 10 days.

242 Tb4-overexpressing transgenic mice treated with CCl4 were susceptible to th

243 Similarly, APP transgenic mice treated with NIR showed a significant re

244 Induction of oral carcinogenesis in transgenic mice using 4-nitroquinoline 1-oxide (4NQO) re

245 n multiple lymphoma models, including huCD27 transgenic mice using the anti-huCD27, varlilumab.

246 vivo imaging studies of alpha-synuclein-GFP transgenic mice using two-photon microscopy showed that

247 aled more injury in hSR-BII, but not hSR-BI, transgenic mice versus WT controls.

248 The microenvironment of estrogen-treated HPV-transgenic mice was significantly enriched for chemokine

249 ic targeting of Channelrhodospin 2 in VGluT2 transgenic mice, we examined the effect of glutamatergic

250 Using inducible Tat-expressing transgenic mice, we found that dopamine subtype 2 (D2) r

251 In female MMTV-HER2/neu transgenic mice, we found that ERalpha and ERbeta expres

252 of various soluble alphaSyn assemblies from transgenic mice, we found that in vitro delivery of exog

253 ssively parallel reporter assays (MPRA), and transgenic mice, we identified disease-linked, biallelic

254 More importantly, using Foxp3-DTR transgenic mice, we show that depletion of regulatory T

255 Using a panel of preterm transgenic mice, we show that epidermis-targeted coexpre

256 Eo771/MUC1-C cells were engrafted into MUC1 transgenic mice, we showed that targeting MUC1-C associa

257 In wild-type and transgenic mice, we traced newly generated IgA-secreting

258 lations, and oncogenic signaling, MMTV-ErbB2 transgenic mice were administered AZD4547 (2-6 mg/kg/day

259 Male FVB/N-Tg(MMTVneu)202Mul/J (Her2) transgenic mice were bred to female MNX mice having FVB/

260 r cells, extracellular vesicles derived from transgenic mice were capable of seeding tau aggregation

261 Here, novel compound transgenic mice were created in which a CXCR5 deficiency

262 solated from neural retinas of neonatal eGFP transgenic mice were injected into the subretinal space

263 Such transgenic mice were largely resistant to highly pathoge

264 comparison with wild-type littermates, hCD39 transgenic mice were protected from acute renal injury a

265 Triple transgenic mice were randomized to receive regular chow

266 APOBEC3 knockout and human APOBEC3A and -3G transgenic mice were tested for their ability to be infe

267 hs of age, tet-off amyloid precursor protein transgenic mice were treated with doxycycline (dox) to s

268 urther evaluate these findings, CaMKIIdeltaC transgenic mice were treated with the beta1-AR blocker m

269 lagen-induced arthritis (CIA) model and DR-1 transgenic mice were used to study the importance of LAI

270 mer that accumulates in adipose tissues from transgenic mice where FAHFAs were first discovered.

271 g the effect of the hGH minigene in TgC6hp55 transgenic mice which express the human TNFR1 under the

272 cells from the ventral skin of the K14-PTHrP transgenic mice [which overexpress parathyroid hormone-r

273 this line with Cre drivers generated double-transgenic mice, which express this sensor in targeted c

274 nts of the rod outer segment photocurrent in transgenic mice, which have only rod function, revealed

275 in intestinal proliferation and apoptosis in transgenic mice whose enterocytes re-enter the cell cycl

276 ation of medroxyprogesterone-treated HLA-DR4 transgenic mice with 5 x 10(5)C. trachomatis D inclusion

277 Using transgenic mice with altered CYP lipid biosynthetic path

278 Transgenic mice with cardiac overexpression of constitut

279 s of wild-type mice and in the myocardium of transgenic mice with cardiomyocyte-specific PDE5 overexp

280 or IRF9 exacerbates neurological disease in transgenic mice with CNS production of IFN-I.

281 exaggerated dermal fibrotic response, while transgenic mice with constitutively elevated adiponectin

282 Transgenic mice with fibroblast-specific activation of m

283 We used transgenic mice with GFP-expressing HCs, coupled with FA

284 analyze the functions of c-Jun, we have used transgenic mice with graded elevation of Schwann cell c-

285 le IL-10(eGFP) Foxp3(mRFP) reporter mice and transgenic mice with impairment in IL-10 receptor signal

286 We imaged pericyte-labeled transgenic mice with in vivo two-photon microscopy to ex

287 We separately generated transgenic mice with inducible expression of proteolytic

288 aging of FFA flux in the liver, we generated transgenic mice with liver-specific expression of lucife

289 To address this question, we generated transgenic mice with mammary-specific FOXC1 overexpressi

290 we examined glucose metabolism in 18-mo-old transgenic mice with muscle-specific overexpression of I

291 tivation timing in inducible tubule-specific transgenic mice with non-diabetic CKD.

292 These actions were examined in RIP-Tag2 transgenic mice with pancreatic neuroendocrine tumors th

293 Similarly, in transgenic mice with redox dysregulation, numbers of PV

294 the adult nigrostriatal system, we generated transgenic mice with reduced TGF-beta signaling in matur

295 ic transmission in wild type mice but not in transgenic mice with reduced TrkB expression in parvalbu

296 Generation of transgenic mice with smooth muscle cell-specific express

297 esioning the LC of male and female P301S tau transgenic mice with the neurotoxin N-(2-chloroethyl)-N-

298 Moreover, immunization of HLA-A*02:01 transgenic mice with the three CD8(+) TEM-cell epitopes

299 eover, immunization of humanized HLA-A*02:01 transgenic mice with the three CD8(+) TEM-cell epitopes

300 Chronic treatment of tau P301S and 5XFAD transgenic mice with this inhibitor reduces tau and APP