ライフサイエンスコーパス: transglutaminase 1

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1 extracellular spaces (positioned to activate transglutaminase-1).

2 s differentiation-dependent genes, primarily transglutaminase 1.

3 ucocerebrosidase, acid sphingomyelinase, and transglutaminase 1.

4 ldren tested positive for IgA against tissue transglutaminase (1.0%; 95% confidence interval, 0.4%-1.

5 crin, ultra-high sulfur matrix proteins, and transglutaminases 1, 2, and 3) did not provide any evide

6 and in a case of lamellar ichthyosis lacking transglutaminase 1 activity.

7 22R-hydroxycholesterol increased transglutaminase 1 and involucrin promoter activity 2- t

8 into the pathophysiology of TGM1 ichthyoses, transglutaminase-1 enzymatic activity, and potential the

9 b, -2f, and -2g proteins), the cross-linking transglutaminase 1 enzyme (Tg-1) and Muc5AC mRNA transcr

10 The loss of transglutaminase 1 enzyme (TGase 1) activity causes lame

11 ated to keratinocyte differentiation, and to transglutaminase 1 expression.

12 strate that mutations of both alleles of the transglutaminase 1 gene are the cause of lamellar ichthy

13 onse element in the proximal promoter of the transglutaminase 1 gene to transcription in normal epide

14 sive, temperature-sensitive mutations in the transglutaminase-1 gene (TGM1).

15 The identification of mutations in the transglutaminase-1 gene as a cause of lamellar ichthyosi

16 le gene mutated in lamellar ichthyosis (LI), transglutaminase-1, in rat keratinocytes, we created an

17 Overexpression of HOXA7 attenuated the transglutaminase 1 induction by phorbol ester, demonstra

18 Antisense HOXA7 expression activated transglutaminase 1, involucrin, and keratin 10 message a

19 ons between the two poles for linkage to the transglutaminase-1 locus on chromosome 14.

20 mRNA and protein levels of involucrin and transglutaminase 1, markers of differentiation, increase

21 tion in the coding region leading to reduced transglutaminase 1 mRNA levels rather than mutation of t

22 AR-gamma activator, increases involucrin and transglutaminase 1 mRNA levels.

23 We also identified two novel transglutaminase 1 mutations in an affected sibling pair

24 to D14S275, a microsatellite marker close to transglutaminase 1 on chromosome 14q11.

25 sed in keratinocytes transfected with either transglutaminase 1 or involucrin promoter-luciferase con

26 HOXA7 overexpression repressed transglutaminase 1-reporter activity.

27 The transglutaminase 1 (TGase 1) enzyme is essential for the

28 The transglutaminase 1 (TGase 1) enzyme is involved in the f

29 mutations in the TGM1 gene that encodes the transglutaminase 1 (TGase 1) enzyme, which is critical f

30 Transglutaminase-1 (TGase-1) is a Ca(2+)-dependent enzym

31 as been associated with loss of keratinocyte transglutaminase 1 (TGase1), an enzyme believed necessar

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