ライフサイエンスコーパス: transglutaminase 2

1 002-1E03 from a digest of gliadin treated by transglutaminase 2.

2 n receptor-related protein 1, MIC2/CD99, and transglutaminase 2.

3 /K18) and ubiquitin that are cross-linked by transglutaminase-2.

4 tabilized by the matrix cross-linking enzyme transglutaminase-2.

5 pounds were not acting through inhibition of transglutaminase 2 activity.

6 Pep1 did not inhibit transglutaminase-2 activity, and incorporation of biotin

7 indicate that suprabasin is a substrate for transglutaminase 2 and 3 activity.

8 Transfection with transglutaminase 2 and htt-N63-148Q-myc followed by trea

9 Calmodulin coimmunoprecipitates with transglutaminase 2 and huntingtin in cells transfected w

10 -links in the HD cortex that colocalize with transglutaminase 2 and huntingtin.

11 dulin colocalizes at the confocal level with transglutaminase 2 and with huntingtin in HD intranuclea

12 lts (for levels of antibodies against tissue transglutaminase-2 and deamidated gliadin peptide), symp

13 nct from the two CD hallmark antigens tissue transglutaminase-2 and deamidated gliadin, exhibiting 71

14 uired for MDB formation, including increased transglutaminase-2 and keratin overexpression, with a gr

15 her epidermally expressed transglutaminases, transglutaminase-2 and transglutaminase-3, on chromosome

16 re down-regulation of cyclin D1, COBRA1, and transglutaminase-2 and up-regulation of tumor necrosis f

17 EMA-positive sera were further tested for transglutaminase 2 antibodies (TG2-IgA).

18 type and detection of anti-gliadin and anti-transglutaminase 2 antibodies to identify a subgroup of

19 Transglutaminase 2 appears to be an important component

20 en fibrillar collagens, introduced by tissue transglutaminase-2, are necessary for the self-assembly

21 activation in different species and identify Transglutaminase 2 as a conserved M2 marker that is high

22 polyglutamine repeats (htt-N63-148Q-myc) and transglutaminase 2 but not in cells transfected with myc

23 celiac disease or antibodies against tissue transglutaminase 2 (controls), healthy family members of

24 We demonstrated previously that transglutaminase 2 cross-links mutant huntingtin in cell

25 e deposits (sCD89, transferrin receptor, and transglutaminase 2) decreased markedly 1 week after trea

26 ERalpha as a direct regulator of macrophage transglutaminase 2 expression, a multifunctional atherop

27 Additionally, transglutaminase-2 expression was determined after YAP s

28 Short interfering RNA was used to knock down transglutaminase-2 expression.

29 re Mesothelin, Muc4, Muc5A/C, Kallikrein 10, Transglutaminase 2, Fascin, TMPRSS3 and stratifin.

30 Transglutaminase 2 has an affinity to the MUC2 CysD2 dom

31 to both human Factor XIII (FXIII) and tissue transglutaminase 2 (hTG2).

32 Whereas the development of anti-transglutaminase 2 IgA is linked with gastrointestinal d

33 patients, who have antibodies against tissue transglutaminase 2 in the absence of villous atrophy.

34 Analysis of transglutaminase 2 knock-out mice confirmed that these c

35 rypsin (modified or unmodified by the enzyme transglutaminase 2) or the peptic-tryptic digest of glia

36 biochemically by blotting with antibodies to transglutaminase-2/p62 proteins and to K8/K18/ubiquitin

37 was cross-linked to germ tubes catalyzed by transglutaminase 2 prior to cell fractionation, immunopr

38 transfection with both htt-N63-148Q-myc and transglutaminase 2 resulted in cross-linking of mutant h

39 Transforming growth factor-beta and transglutaminase 2 stimulate Snail-dependent invadosome

40 infiltrating T cells, HLA-DR expression, and transglutaminase 2-targeted IgA deposits.

41 evious work in our laboratory has shown that transglutaminase 2 (TG2) acting as a coreceptor for inte

42 s of total IgA antibodies, IgA antibodies to transglutaminase 2 (TG2) and endomysium, as well as IgA

43 Antibodies to the autoantigen transglutaminase 2 (TG2) are a hallmark of celiac diseas

44 Autoantibodies specific for the enzyme transglutaminase 2 (TG2) are a hallmark of the gluten-se

45 A plasma cells (PCs) specific for the enzyme transglutaminase 2 (TG2) are abundant in the small intes

46 Transglutaminase 2 (TG2) catalyzes transamidation or dea

47 Transglutaminase 2 (TG2) expression is required for epid

48 to hypertrophy, associated with up-regulated transglutaminase 2 (TG2) expression, mediates not only p

49 Tissue transglutaminase 2 (TG2) has been of particular interest

50 Molecular deletion of transglutaminase 2 (TG2) has been shown to improve funct

51 Genetic ablation of enzyme transglutaminase 2 (TG2) in Mgp(-/-) mice dramatically r

52 The mechanism of activation of transglutaminase 2 (TG2) in the extracellular matrix rem

53 that it is a substrate for cross-linking by transglutaminase 2 (TG2) into higher-order species.

54 Transglutaminase 2 (TG2) is a Ca(2+)-dependent cross-lin

55 Transglutaminase 2 (TG2) is a distinctive member of the

56 Transglutaminase 2 (TG2) is a multifunctional enzyme tha

57 Tissue transglutaminase 2 (TG2) is a multifunctional protein pr

58 Transglutaminase 2 (TG2) is a multifunctional protein th

59 Transglutaminase 2 (TG2) is a ubiquitously expressed enz

60 Transglutaminase 2 (TG2) is a ubiquitously expressed enz

61 Human transglutaminase 2 (TG2) is believed to play an importan

62 Tissue transglutaminase 2 (TG2) is overexpressed in epithelial

63 Transglutaminase 2 (TG2) is secreted by a non-classical

64 The multifunctional, protein cross-linking transglutaminase 2 (TG2) is the main autoantigen in celi

65 The multifunctional enzyme transglutaminase 2 (TG2) is the target of autoantibodies

66 l commercial assays that measure IgA against transglutaminase 2 (TG2) or IgG against DGP.

67 e is presented in this study that shows that transglutaminase 2 (TG2) plays a critical role in the ad

68 For example, Trx activates extracellular transglutaminase 2 (TG2) via reduction of an intramolecu

69 n 1 (MTA1), a master chromatin modifier, and transglutaminase 2 (TG2), a multifunctional enzyme, are

70 Macrophage expression of transglutaminase 2 (TG2), a multifunctional protein with

71 cross-linked by transamidation catalyzed by transglutaminase 2 (TG2), itself an inflammation-regulat

72 aspase-3 activation through stabilization of transglutaminase 2 (TG2), which cross-links and inactiva

73 ion plasma cells (PCs), we have analyzed the transglutaminase 2 (TG2)-specific VH:VL autoantibody rep

74 odies reactive to gluten or the self-antigen transglutaminase 2 (TG2).

75 on of autoantibodies specific for the enzyme transglutaminase 2 (TG2).

76 isfolded keratins; 2) elevated levels of the transglutaminase 2 (TG2); 3) increased K8 phosphorylatio

77 Transglutaminase 2 (TG2, a.k.a. tissue transglutaminase)

78 tein keratin 8 (K8) and its cross-linking by transglutaminase-2 (TG2) are essential for MDB formation

79 Transglutaminase-2 (TG2) is a new anti-fibrotic target f

80 Transglutaminase 2 (TGase 2) expression is increased in

81 Interactions among IgA, CD71, and transglutaminase 2 (Tgase2) were analyzed by flow cytome

82 es the AP-1 transcription factor Fos and the transglutaminase 2 (TGase2), a cross-linking enzyme with

83 Transglutaminase-2 (TGM-2) has been implicated in severa

84 We identified transglutaminase 2 (TGM2) as a putative tumor suppressor

85 binding 1(Id1), fos-like antigen 1 (FOSL1), transglutaminase 2 (TGM2), asparagine synthetase (ASNS),

86 up 10 secretory phospholipase A2, Wnt5a, and transglutaminase 2 (Tgm2).

87 ell culture models, and this requires active transglutaminase-2 (TGM2).

88 transition gene signature characteristic of transglutaminase 2/transforming growth factor-beta activ

89 uced mesangial surface expression of TGase2 (transglutaminase 2), which in turn up-regulated TfR1 exp