ライフサイエンスコーパス: transhydrogenase

1 nvolving the mitochondrial membrane NAD/NADP transhydrogenase.

2 it of the membrane-bound pyridine nucleotide transhydrogenase.

3 domains I and III from Rhodospirillum rubrum transhydrogenase.

4 d protein kinase and nicotinamide nucleotide transhydrogenase.

5 mbles the organization of nucleotides in the transhydrogenase active site in the crystal structure.

6 Oxidase and transhydrogenase activities are preserved in all mutants

7 Mutants lacking transhydrogenase activity also have higher levels of glu

8 For example, cells lacking transhydrogenase activity can utilize methanol as a sole

9 Mutants lacking transhydrogenase activity have phenotypic and physiologi

10 Transhydrogenase activity is observed using NADH and thi

11 alpha-ketoglutarate, namely an FAD-dependent transhydrogenase activity using pyruvate as a hydrogen a

12 aerobic methanol resistance to cells lacking transhydrogenase activity.

13 is the only flavin cofactor required for the transhydrogenase activity.

14 notransferase [Got2] and hydroxyacid-oxoacid transhydrogenase [Adhfe1]).

15 h mitochondrial GSH is maintained largely by transhydrogenase and isocitrate dehydrogenase, the mecha

16 NADPH-dependent peroxidase, NADH/NADP+ transhydrogenase, and glucose-6-phosphate dehydrogenase

17 at shock protein 60, nicotinamide nucleotide transhydrogenase, and superoxide dismutase.

18 itrobenzoic acid) (DTNB) reductase, oxidase, transhydrogenase, and, in the presence of AhpC, peroxide

19 the C-terminal end of Ec pyridine nucleotide transhydrogenase beta subunit.

20 mplex to that in the complete membrane-bound transhydrogenase, but the rates of forward and reverse t

21 Since transhydrogenase can be a major source of NADPH, loss of

22 xylases, hybrid cluster proteins, proteases, transhydrogenase, catalase, and several putative protein

23 lated dI and dIII from Rhodospirillum rubrum transhydrogenase catalyse a rapid, single-turnover burst

24 Transhydrogenase catalyses the transfer of reducing equi

25 )dIII(1) complex) from Rhodospirillum rubrum transhydrogenase catalyzes fast single-turnover hydride

26 doxin:NADP+ reductase family of flavoprotein transhydrogenases, catalyzes the NADH-dependent reductio

27 of the RC-LH1-PufX, ATP synthase and NAD(P)H transhydrogenase complexes, as well as showing that the

28 Transhydrogenase comprises three domains.

29 o enzyme data show that a not yet identified transhydrogenase could potentially reoxidize approximate

30 Transhydrogenase couples reversible hydride transfer fro

31 Transhydrogenase couples the redox (hydride-transfer) re

32 Transhydrogenase couples the redox reaction between NADH

33 Transhydrogenase couples the transfer of hydride-ion equ

34 preparation of a partially degraded E. coli transhydrogenase (ecbeta) was examined.

35 Large increases in pyridine cofactor transhydrogenase flux, correcting imbalanced production

36 rotonmotive force alters the affinity of the transhydrogenase for substrates, accelerates the rate of

37 Transhydrogenase, found in bacterial membranes and inner

38 Domain III of transhydrogenase from Rhodospirillum rubrum was expresse

39 studies and supports the notion that intact transhydrogenase functions by an alternating site mechan

40 ADH, were enabled by direct mutations to the transhydrogenase genes sthA and pntAB The phosphotransfe

41 ent glutathione reductase, or the NADH/NADPH transhydrogenase, indicating that matrix GSH regeneratio

42 mitochondrial enzyme nicotinamide nucleotide transhydrogenase (Nnt) in pancreatic beta-cells.

43 Nicotinamide nucleotide transhydrogenase (NNT) is a mitochondrial enzyme that tr

44 Nicotinamide nucleotide transhydrogenase (NNT) is a mitochondrial redox-driven p

45 notype was mapped to nicotinamide nucleotide transhydrogenase (Nnt) on mouse chromosome 13, a nuclear

46 at the deficiency of nicotinamide nucleotide transhydrogenase (NNT) protein in C57BL/6J is responsibl

47 forward reaction of nicotinamide nucleotide transhydrogenase (NNT) reduces NADP(+) at the expense of

48 n, the gene encoding nicotinamide nucleotide transhydrogenase (Nnt) was found to be defective in C57B

49 We hypothesized that nicotinamide nucleotide transhydrogenase (Nnt), which utilizes the proton gradie

50 Although nicotinamide nucleotide transhydrogenase (NNT)-deficient C57BL/6J (6J) mice are

51 locator 1 (ANT1) and nicotinamide nucleotide transhydrogenase (NNT)], we selectively impaired mitocho

52 e energy-transducing nicotinamide nucleotide transhydrogenases of mammalian mitochondria and bacteria

53 The nicotinamide nucleotide transhydrogenases of mitochondria and bacteria are proto

54 The nicotinamide nucleotide transhydrogenases of mitochondria and bacteria are proto

55 modification of reduced AhpF does not affect transhydrogenase or oxidase activities.

56 Pyridine nucleotide transhydrogenase (PntAB) is an integral membrane protein

57 Nicotinamide dinucleotide binding to transhydrogenase purified from Escherichia coli was inve

58 We define the mechanism of the transhydrogenase reaction as follows: NADPH binding, hyd

59 P450 reductase catalyzes a transhydrogenase reaction between NADPH and oxidized nuc

60 , as demonstrated by a hydride ion exchange (transhydrogenase) reaction between NADPH and NADP(+) or

61 ever, the relatively simple structure of the transhydrogenase recommends it as a model for study of t

62 ase (cb(5)r) and other members of the flavin transhydrogenase superfamily of oxidoreductases.

63 Transhydrogenase (TH) couples direct and stereospecific

64 Proton-translocating transhydrogenase (TH) couples direct and stereospecific

65 Transhydrogenase (TH) is a dimeric integral membrane enz

66 Nicotinamide nucleotide transhydrogenase (TH), a membrane enzyme present in both

67 In intact, membrane-bound transhydrogenase, the substitution completely abolished

68 esting because most heterotrophs rely on the transhydrogenase, the TCA cycle, and the oxidative pento

69 ontent, rate constant for NADPH release, and transhydrogenase turnover rates allowed us to estimate t

70 del will be presented to explain the role of transhydrogenase under aerobic conditions when cells nee

71 Detergent-free transhydrogenase was deposited as a thin film on an ATR

72 component (dI) of the Rhodospirillum rubrum transhydrogenase was substituted with Asn (to give dI.Q1

73 esidues of domain II of the Escherichia coli transhydrogenase were mutated, and the mutant enzymes we

74 nd to isolated dI from Rhodospirillum rubrum transhydrogenase with similar affinity to the physiologi

75 to the mechanism of energy transduction, the transhydrogenase works according to the same principles