ライフサイエンスコーパス: transitional

1 Transitional 1 (T1) B cells were the most dependent upon

2 fies distinct populations that correspond to transitional 1 (T1), transitional 2 (T2), follicular mat

3 significantly reduced the numbers of B1 and transitional 1 B cells.

4 h leads to a B cell maturation arrest at the transitional 1 stage.

5 evidence that in Ly9-deficient mice splenic transitional 1, MZ, and B1a B cells are markedly expande

6 hat MZ B cell development was blocked at the transitional-1 to transitional-2-MZ precursor stage in t

7 ered in the absence of the protein, although transitional 2 (T2) B cell populations were depressed in

8 ions that correspond to transitional 1 (T1), transitional 2 (T2), follicular mature, and marginal zon

9 lopment was blocked at the transitional-1 to transitional-2-MZ precursor stage in the absence of func

10 network is sufficient to compose steady and transitional 3-D locomotion behaviours including walking

11 network is sufficient to compose steady and transitional 3-D locomotion behaviours, including walkin

12 Finally, CD19(+)CD24(++)CD38(++) transitional and CD19(+)CD24(-)CD38(-) new memory B-cell

13 AD is accompanied by systemic expansion of transitional and chronically activated CD27(+) memory, p

14 s and farmers as well as differences between transitional and intensive farmers in mandibular variati

15 ne, patients had lower median percentages of transitional and mature B cells than age-matched healthy

16 The antibody-coding genes from new emigrant/transitional and mature naive B cells were cloned and as

17 ased in the patients, whereas frequencies of transitional and naive B cells were decreased.

18 We observed normalization of circulating transitional and naive B cells, reduction in PD-1(+)CD4(

19 ating B-cell pool consisted predominantly of transitional and naive cells, with a marked deficiency o

20 Analysis of samples from transitional and persistent phases of infection demonstr

21 Lung function declined more rapidly among transitional and post-menopausal women, in particular fo

22 IFN-beta treatment increases transitional and regulatory B cell populations, as well

23 indices are also obtained with the design of transitional and rotational symmetry modification.

24 affect Golgi cisternal progression, early-to-transitional and transitional-to-late, respectively.

25 equencies of plasmablasts and naive, memory, transitional, and activated B cells.

26 hree 1-year periods were defined: pre-PCV13, transitional, and post-PCV13.

27 y dividing the study period into 3 DES eras: Transitional (April 23, 2003, to June 30, 2004); Liberal

28 We also demonstrate that succeeding 'transitional' archaeological industries, one of which ha

29 hich is located in retinotopically organized transitional area V4 (V4t).

30 he association between Neandertals and this "transitional" assemblage has been controversial because

31 effect against anti-IgM apoptotic signals on transitional B cell checkpoint, not observed with BAFF.

32 When modeled as a time-dependent covariate, transitional B cell frequencies (but not total B cells o

33 No association between transitional B cell proportions and either de novo donor

34 A) formation was evident, although preserved transitional B cell proportions were associated with red

35 Flow cytometry analysis of the splenic transitional B cell subsets demonstrated that MZ B cell

36 s and found that subsets of CD24(hi)CD38(hi) transitional B cells (TrBs), CD24(hi)CD27(+) memory B ce

37 In the periphery transitional B cells accumulated under ERT, and the defe

38 igen-dependent negative selection of splenic transitional B cells and is required for activation of t

39 se delta (PI3Kdelta) lead to accumulation of transitional B cells and senescent T cells, lymphadenopa

40 pitope (SP62): in C57BL/6 mice, SP62-binding transitional B cells are readily identified in bone marr

41 for WP ontogeny, and CXCL13-responsive late transitional B cells are the initiating subset.

42 n receptor (BCR) signaling determine whether transitional B cells become marginal zone B (MZB) or fol

43 od, and spleen in mice and humans shows that transitional B cells comprise a much smaller fraction in

44 the first time, the study reveals that human transitional B cells encompass not only transitional typ

45 eased frequency of autoreactive new emigrant/transitional B cells exiting the BM, indicating that the

46 BAFF-mediated humoral autoimmunity, TACI(+) transitional B cells from BAFF-transgenic mice spontaneo

47 In addition, we found that transitional B cells from both healthy controls and IFN-

48 at IL-4 stimulated the generation of CD23(+) transitional B cells from CD23(-) B cells, and this effe

49 y low frequency of polyreactive new emigrant/transitional B cells in DOCK8-deficient patients.

50 number of regulatory CD19(+)CD24(++)CD38(++) transitional B cells in peripheral blood relative to tre

51 cisely downmodulated upon culture of splenic transitional B cells in the presence of BAFF.

52 d for optimal survival and TLR7 responses of transitional B cells in the spleen and was overexpressed

53 A substantial influx of CXCR5(+) transitional B cells into the spleen occurred 18 h befor

54 ells is reduced and the frequency of CD27(+) transitional B cells is increased in patients with autoi

55 Finally, we identified transitional B cells isolated from CV facilities as poss

56 a significant increase in naive, memory, and transitional B cells on day 30 after vaccination, wherea

57 An increased percentage of peripheral transitional B cells producing IL-10 has been observed i

58 CD24(high)CD38(high) transitional B cells represent cells at a key stage in t

59 were relatively unperturbed, WASp-deficient transitional B cells showed enhanced proliferation in vi

60 4(high) B10 cells, CD24(hi)CD38(hi) immature transitional B cells, and CD73(-)CD25(+)CD71(+) BR1 cell

61 r, breakage of tolerance, increased immature/transitional B cells, B cell malignancies, as well as a

62 demonstrate that B cells, and in particular transitional B cells, can promote prolongation of graft

63 th increasingly elevated Flt3L, depletion of transitional B cells, CD56(bright) NK cells, naive T cel

64 B cells, as well as IL-10-producing CD27(+) transitional B cells.

65 ity via direct, TACI-dependent activation of transitional B cells.

66 biased by IS regimens, which also influenced transitional B cells.

67 enic B cells and a further pronounced one in transitional B cells.

68 FF promotes the expansion of TACI-expressing transitional B cells.

69 ance via positive selection of self-reactive transitional B cells.

70 secretion as was observed in healthy control transitional B cells.

71 tional studies suggest an important role for transitional B lymphocytes (CD19 + CD24hiCD38hi) in prom

72 Bregs were identified in both the naive and transitional B-cell compartments and suppressed T-cell p

73 Blood transitional B-cell numbers were normal, but naive matur

74 mory B cells, with a concomitant increase in transitional B-cell numbers.

75 They arise from within the transitional B-cell subpopulation and are characterised

76 study indicates that altered distribution of transitional B-cell subsets highlights different regulat

77 +)CD27(+) memory and CD19(+)CD24(hi)CD38(hi) transitional B-cell subsets in healthy human donors.

78 B-cell progenitors in the bone marrow and of transitional B-cell subsets in the spleen.

79 ides evidence for the existence of different transitional B-cell subsets, each displaying unique phen

80 ight on a new alternative mechanism by which transitional B-cells inhibit T-cell proliferation and cy

81 Here we show that transitional B-cells produced more IL-10 and expressed h

82 his stimulatory condition, CD86 expressed by transitional B-cells was down regulated and T-cell proli

83 at the down-regulation of CD86 expression by transitional B-cells was due to the autocrine effect of

84 s innate response activator (IRA) B cells, a transitional B1a-derived inflammatory subset which contr

85 e both characterized by the expansion of the transitional basal progenitor cells.

86 On ectopic expression of CDX2, these transitional basal progenitors differentiate into intest

87 from the Oligocene of South Carolina that is transitional between raptorial archaeocete whales and mo

88 10(-4) s/n/r for Hong Kong 2014 (H3N2) and a transitional bias of 2.7-3.6.

89 d microscopic damage processes, resulting in transitional brittle to semi-brittle modes under P and T

90 g use, avoidance of adverse drug events, and transitional care activities focusing on medication reco

91 atients receiving loop diuretics at the Yale Transitional Care Center (N=162) and (2) interventional

92 At the Yale Transitional Care Center, 31.5% of patients had hypochlo

93 ng treatment with loop diuretics at the Yale Transitional Care Center.

94 F management strategy that includes tailored transitional care for patients discharged from the ED or

95 ing patients who could benefit from tailored transitional care including early follow-up and booster

96 -based observation are not included in these transitional care initiatives.

97 enter randomized trial of a patient-centered transitional care intervention in patients with acute he

98 The statement describes transitional care interventions and outcomes and discuss

99 by systems or providers seeking to implement transitional care interventions for persons with HF.

100 Transitional care may be effective in improving short-te

101 ver support, community partnerships, and new transitional care personnel.

102 ients at high risk for delirium and tailored transitional care planning may help to maximize the func

103 As transitional care programs become the new normal for pat

104 Of transitional care reports, there was much heterogeneity

105 e discharge summary to serve as an effective transitional care tool.

106 derstand the current state of the science of transitional care, as discussed in the available researc

107 rtunities remain for improving heart failure transitional care.

108 and managing polypharmacy are central to HF transitional care.

109 sted odds ratio 1.52; 95% CI 1.19-1.95), and transitional case management (1.65; 1.36-1.99), receipt

110 linkage to HIV care (LTC) and the effect of transitional case management services.

111 )) and concomitantly decreasing the immature transitional (CD27(-)IgD(+)CD38(+)), unswitched memory (

112 tibodies is directed toward nonneutralizing, transitional, CD4-inducible (CD4i) epitopes associated w

113 Transitional cell carcinoma (TCC), the most common cance

114 onsidered related to the study drug (bladder transitional cell carcinoma in the ozanezumab group and

115 We present four cases of transitional cell carcinoma of the transplant ureter (TC

116 s accrued from patients with muscle-invasive transitional cell carcinoma of the urinary bladder (TCC-

117 n of the bladder tumor and biopsy identified transitional cell carcinoma or urothelial carcinoma inva

118 A continuum of transitional cell states exists between these discrete s

119 TACI(+) transitional cells from BAFF-transgenic mice are charact

120 Akap12-/- prostate lobes suggests that these transitional cells may be the source of the lymph node m

121 Severe B-cell deficiency affects mature and transitional cells, mimicking the action of rituximab.

122 artment, enriched for CXCL13-responsive late transitional cells.

123 A similar transitional columnar epithelium is present at the trans

124 Here we describe a transitional columnar epithelium with distinct basal pro

125 er, we show that they partially overlap on a transitional compartment.

126 nd propose an atomic model of the 11-subunit transitional complex.

127 or mandibular attachment of the middle ear-a transitional condition of the predecessors to crown Mamm

128 ergic ChAT-ir neurons were also found within transitional cortical areas (insular, cingulate, and pir

129 ) Id2(+) fetal ILC precursors that express a transitional developmental phenotype (ftILCPs) and diffe

130 , recirculating RTEs encounter TRAs during a transitional developmental stage that facilitates tolera

131 ing the rotational diffusion with respect to transitional diffusion alters the kinetic pathways of se

132 ransition from high-biomass moist forests to transitional dry forests and woody savannah-like states.

133 gnon gas, resulting in strikingly unexpected transitional dynamics of Bose-Einstein magnon condensate

134 opausal status was defined as nonmenopausal, transitional, early postmenopausal, and late postmenopau

135 eavers in the boreal system will only have a transitional effect on MeHg in the environment.

136 and where the position of the thoracolumbar transitional element was.

137 cer stem cell population in a mouse model of transitional epithelial carcinoma and uncover a novel me

138 suppressors is unable to yield tumors in the transitional epithelium lining the bladder, kidneys and

139 on serves as a source of progenitors for the transitional epithelium.

140 DES use varied, from 56% in the Transitional era to 85% in the Liberal era and 62% in th

141 al era were significantly better than in the Transitional Era, but not significantly better than in t

142 ips in the pressure-derivative curves in the transitional flow period were observed as soon as pressu

143 dynamic conductivity were observed after the transitional flow period.

144 anial support for Eunotosaurus as a critical transitional form in turtle evolution, thus fortifying a

145 on can be revealed by integrating fossils of transitional forms with direct experimentation in the la

146 from molecules and morphology and a lack of transitional fossils from the critical time interval.

147 Transitional fossils informing the origin of turtles are

148 Here, we compare the plastid genomes of two "transitional" green algae: the photosynthetic, mixotroph

149 Estuaries are transitional habitats characterized by complex biogeoche

150 of biotic communities in estuaries and other transitional habitats.

151 resenting a new species, Teyujagua paradoxa, transitional in morphology between archosauriforms and m

152 There was a transitional increase in Gli-1/2 gene expression levels

153 ; 95% CI, 1.11 to 1.15; P<0.001) without any transitional increase in risk at a threshold of two SIRS

154 03(-) eTreg subset displayed properties of a transitional intermediate between cTregs and more activa

155 towards increased herbivory across the K-Pg transitional interval.

156 his interfacial layer can be used to build a transitional layer (second adlayer) mediated by interlay

157 This transitional layer can be easily removed by annealing ab

158 pping of bio-organic molecules as the second transitional layer that is stable up to 175 degrees C.

159 with shorter disease duration compared with transitional LBD (beta, -1.52; 95% CI, -2.11 to -0.93; P

160 with shorter disease duration compared with transitional LBD, and this effect is independent of Braa

161 In this study, we assessed how key transitional life events and exposure to different nutri

162 on transitions predicted others' experienced transitional likelihoods with high accuracy.

163 (PLC-PDXs) from 20 hepatoblastomas (HBs), 1 transitional liver cell tumor (TCLT), 1 hepatocellular c

164 oward such transformations generally produce transitional lumbosacral vertebrae that are incompletely

165 Multiple endothelial cell integrins bind transitional matrix proteins, including alpha5beta1, alp

166 Endothelial cell interactions with transitional matrix proteins, such as fibronectin, occur

167 Vibrio vulnificus YJ016, which represents a transitional member between subfamiles 1 and 2.

168 n 4 patients, pools of resting and activated transitional memory (T(TM)) CD4(+) T cells were found to

169 we found that the level of SIV DNA in CD4(+) transitional memory (TTM) and effector memory (TEM) T ce

170 of 0.9-, 1.1-, 1.5-, and 3.7-fold for CD4(+) transitional memory [TTM], TCM, effector memory [TEM], a

171 activation mirrored the effector and central/transitional memory CD4 T cell contribution to the pool

172 t virus in both cell subsets, we showed that transitional memory cells may not be a durable reservoir

173 ubsets of CD4(+) T cells, central memory and transitional memory cells, were reported to be major res

174 Latent infection appears to wane within the transitional memory compartment in patients who have sus

175 T cells, specifically the central (TCM) and transitional memory compartments, harbor the highest lev

176 , the majority of foreskin T cells exhibited transitional memory or effector memory phenotype and exp

177 r memory T cell subsets, such as central and transitional memory T cells (TCM and TTM, respectively).

178 ative signature predominantly in a subset of transitional memory T cells, whereas PD-1 blockade inste

179 Graphene decorated with 5d transitional metal atoms is predicted to exhibit many in

180 stems of nodes (mononuclear, polynuclear, or transitional metal cluster complexes) joined together vi

181 ctronic device based on two dimensional (2D) transitional metal dichalcogenides (TMDs), finding a low

182 ry, stacking orders and spin-orbit coupling, transitional metal dichalcogenides have shown a lot of f

183 absorption exhibited by single atomic layer transitional metal dichalcogenides in the visible to nea

184 bricate well-defined iron oxy-hydroxides and transitional metal doped iron oxy-hydroxides nanomateria

185 on-metal signaling, where dynamic changes in transitional metal pools can modulate protein function,

186 aining resource requirements and competitive transitional milestones are substantial.

187 Previous studies have suggested a number of transitional models, although the nature of magnetite at

188 Transitional morphologies are found in the middle unit o

189 een obscured by the scarcity of fossils with transitional morphologies.

190 This represents a transitional morphology between the primitive, multivalv

191 This transitional morphology had previously been hypothesized

192 y grouped into palaeo-biomes, we show a more transitional nature of terrestrial climate change by ind

193 fluorescence, which reflects formation of a transitional NBD1 conformation, was followed by its SUMO

194 that Hsp27-Ubc9 targets the SUMOylation of a transitional, non-native conformation of F508del NBD1: (

195 nset asthma were increased in women who were transitional (odds ratio, 2.40; 95% CI, 1.09-5.30), earl

196 stubby/wide, thin, mushroom-like, ramified, transitional or atypical aspects.

197 This study included 807 participants with transitional or diffuse LBD (mean [SD] age, 70.0 [9.9] a

198 nter database included 807 participants with transitional or diffuse LBD.

199 surface IgM expression on immature (but not transitional or mature) anti-insulin B cells in the NOD

200 processes and also reveal the presence of a transitional, or "limbo," state of the original memory b

201 Together, this route represents a transitional pathway between the classic pathway and the

202 Moreover, the presence of a transitional pathway for haem biosynthesis within many G

203 uring a period of high SP use (1999-2001), a transitional period (2007-2008), and a period of low SP

204 lly transmitted infections (STIs) during the transitional period following foster care.

205 l, behavioral, and biological models of this transitional period hinge on the Chatelperronian technoc

206 ver a woman's lifetime are largely shaped by transitional periods such as puberty, menopause and preg

207 that identify biomarkers associated with the transitional phase between health and periodontal diseas

208 at peri-implant mucositis an important early transitional phase during the development of peri-implan

209 After the initial transitional phase from SFM to FFDM, population-based sc

210 In contrast, during the transitional phase of infection, the level of expression

211 r, while adolescence represents an important transitional phase, the nature of young adult wheeze has

212 ale of analysis of brain architecture is the transitional point between a microscopic scale where ind

213 responses within LO-1, perhaps indicating a transitional point between those two organizational prin

214 d, additional resources should be devoted to transitional postdoctoral fellowships already offered by

215 opose that the CXCR4(hi) subset represents a transitional premonocyte population, and that this seque

216 prey availability on right whale demographic transitional probabilities and use a corresponding demog

217 vidence for the auditory system prioritizing transitional probabilities over probabilities of individ

218 Forming representations for transitional probabilities paves the way for predictions

219 If deviance detection was based on transitional probabilities, then reversal deviants shoul

220 sts, including price of drug, utilities, and transitional probabilities, were included from published

221 ies on probabilities of sound patterns or on transitional probabilities.

222 nd cortical auditory deviance detection uses transitional probabilities.

223 ty with which a given sound follows another (transitional probability) allows predictions of upcoming

224 g of p63(+)/CK5(+) progenitor, CK5(+)/CK8(+) transitional progenitor, and CK8(+) differentiated lumin

225 ult, adolescent; (2) adolescent development, transitional programs, transition to adult care; (3) mus

226 , respectively, and both are required in the transitional pronation step.

227 iven for wall turbulence regeneration in the transitional regime--laterally coupled, diffusively--whi

228 The transitional region of 200-250 kilometres in width is le

229 hane/methane enhancement ratios bridged by a transitional region.

230 Immature transitional regulatory B (itBreg) cells are innate-like

231 ve study supports the potential relevance of transitional ("regulatory") B cells as a biomarker and t

232 how that IFN-beta pushes some B cells into a transitional, regulatory population that is a critical m

233 al adjacent to the superchrons, indicating a transitional reversing state to the superchrons.

234 ions and stable regimes, along with distinct transitional routes into chaos.

235 In transitional rural communities from low-income countries

236 We find a transitional sleep stage associated with a 7-10 Hz oscil

237 m a dimethyl sulfoxide (DMSO) solution via a transitional SnI2.3DMSO intermediate phase.

238 largely because there is a lack of data from transitional species.

239 and extrinsic factors regulating survival of transitional stage 1 (T1) B cells are unknown.

240 eads to a loss of splenic B cells beyond the transitional stage 1.

241 CD1d(hi) B10 cells, CD21(hi)CD23(hi)CD24(hi) transitional stage 2-like B cells, and CD138(+) plasma c

242 nenzymatic replication of RNA is a potential transitional stage between the prebiotic chemistry of nu

243 Protoclaviger captures a transitional stage in the evolutionary development of th

244 The transitional stage of B cell development is a formative

245 2 (Bcl2), despite a persisting block at the transitional stage.

246 biochemical indices, and one main peak was a transitional stage.

247 velopment and an expansion of B cells at the transitional stage.

248 6-deficient B cells between the immature and transitional stage.

249 e role of long non-coding (lnc) RNAs in this transitional stage.

250 expression is highest during vegetative and transitional stages of meristem maturation, and CRISPR/C

251 in vitro B cell maturation, from immature to transitional stages, and its influence on BCR-mediated n

252 re anti-insulin B cells, with less impact at transitional stages.

253 sory and premotor network and suggest that a transitional state from wakefulness to unconsciousness i

254 their genes to remain active and maintain a transitional state in an ever-changing transcriptional l

255 e and more derived characters highlights its transitional state in the Pamphilioidea and complex mosa

256 irect programming path diverges into a novel transitional state rather than following the expected em

257 he cohort level suggest that it represents a transitional state to be passed through during the inter

258 compared with thymic Treg, confirming their transitional state.

259 eage-status but also stemness, plasticity in transitional states and differentiation.

260 ker length on the peptides' interaction with transitional states of F, solubility, membrane insertion

261 EDICTS (Epi-mark Descriptor Imaging of Cell Transitional States), to discern chromatin organizationa

262 mations interconnected within an ensemble of transitional states.

263 k functionally diverse subgroups and exhibit transitional structural features that may help explain r

264 eview demonstrates the beneficial effects of transitional support strategies for newly qualified nurs

265 as well as augmenting apoptosis of immature transitional T1 B cells, including insulin-specific B ce

266 Type 1 transitional (T1) B cells required Taok3 to rapidly resp

267 ers of RBP-reactive marginal zone precursor, transitional T3, and PDL-2(+)CD80(+) memory B cells, wit

268 The term "transitional tissue remodeling" describes qualitative an

269 s develop anergy and partial deletion at the transitional to mature B cell stage, but become Env(-) u

270 t in self-reactive cells specifically at the transitional to naive mature B cell stage in WAS subject

271 ernal progression, early-to-transitional and transitional-to-late, respectively.

272 rrow sense defined herein, we found that the transitional-turbulent spot inception mechanism is analo

273 en a streak is infected by a nearby existing transitional-turbulent spot.

274 ore, not the mechanisms for the inception of transitional-turbulent spots found here.

275 Although structurally quite similar to the transitional-turbulent spots, these turbulent-turbulent

276 ilitate the growth and spreading of existing transitional-turbulent spots.

277 uman transitional B cells encompass not only transitional type 1 and type 2 B cells, as previously su

278 this deficit is centered on the inability of transitional type 1 B cells to survive and to progress t

279 cells to survive and to progress toward the transitional type 2 B cell stage, whereas cells that hav

280 f transcriptional programs during a critical transitional window of meristem maturation, which we pro

281 confidence interval [CI], -13.1 to -7.2) in transitional women and -12.5 ml/yr (95% CI, -16.2 to -8.

282 ased by -3.8 ml/yr (95% CI, -6.3 to -2.9) in transitional women and -5.2 ml/yr (95% CI, -8.3 to -2.0)

283 ded into 3 subgroups: pre-PCV13 (2007-2009), transitional year (2010), and post-PCV13 (2011-2013).

284 Intriguingly, these transitional ZO-1 binding/release and channel-aging step

285 rate in retinitis pigmentosa (RP) and in the transitional zone (TZ) of atrophic zones (AZ), which cha

286 ific cartilage zones (superficial zone [SZ], transitional zone [TZ], and deep zone [DZ]) and regions

287 hrough inhibitory scar tissue at the CNS-PNS transitional zone before entering into a pro-regenerativ

288 istribution of M. burtoni, specifically in a transitional zone between Asia and Australia (Wallacea),

289 In several organ systems, the transitional zone between different types of epithelium

290 of a matrix of wooded savanna that formed a transitional zone between the extremes of humid eastern

291 nside or at the edge of WTs, with an obvious transitional zone between WT and MEC.

292 d on histological morphology, especially the transitional zone between WT and MEC.

293 ur findings reveal a previously unidentified transitional zone in the epithelium of the upper gastroi

294 esions and to T2-weighted imaging scores for transitional zone lesions were calculated.

295 s in the peripheral zone were 0.47 and 0.15; transitional zone, 0.37 and 0.07; diffusion-weighted MR

296 eripheral zone were 0.51 and 0.17 and in the transitional zone, 0.45 and -0.11; at diffusion-weighted

297 Transitional zones of hypoxia also exhibited elevated le

298 tional columnar epithelium is present at the transitional zones of other mouse tissues (including the

299 and the central gland (combined central and transitional zones) between men with biopsy confirmed pr

300 focal fibroplasia was observed at the airway transitional zones.