ライフサイエンスコーパス: translational regulation

1 l deconvolution to assess cell-type-specific translational regulation.

2 abundance of RecA isoforms, possibly through translational regulation.

3 collagen stabilization, hypoxia sensing, and translational regulation.

4 ctly to the mechanism of riboswitch-mediated translational regulation.

5 ss involving selective mRNA localization and translational regulation.

6 respective impacts on transcriptional versus translational regulation.

7 A-protein pairs that are candidates for post-translational regulation.

8 el of complexity to cellular transcriptional/translational regulation.

9 st and may perform noncanonical functions in translational regulation.

10 of OCT4A, but little is known about its post-translational regulation.

11 ization is the lineage-specific evolution of translational regulation.

12 evelopment, little is known about their post-translational regulation.

13 A that is important for its localization and translational regulation.

14 genes involved in chromatin modification and translational regulation.

15 the evolution of protein dual targeting and translational regulation.

16 adherin mRNA or protein levels suggests post-translational regulation.

17 CX-A reflects a role of this protein in mRNA translational regulation.

18 tle difference at the mRNA level, suggesting translational regulation.

19 characterize the mechanism of Puf6p-mediated translational regulation.

20 tial differences between transcriptional and translational regulation.

21 5 alpha expression through an IRES-dependent translational regulation.

22 motif is required for LS assembly-dependent translational regulation.

23 no difference at the mRNA level, suggesting translational regulation.

24 ted axonal mRNA redistribution for localized translational regulation.

25 s, and enterocytes, is postulated to undergo translational regulation.

26 olysomes, suggesting their potential role in translational regulation.

27 re mediated by modulating cell signaling and translational regulation.

28 rs, suggest that ATX2 plays a direct role in translational regulation.

29 on factor 4E distinguishes a novel system of translational regulation.

30 ing protein kinases essential for their post-translational regulation.

31 We conclude that community effects exist in translational regulation.

32 ol, suggesting a means of reinforcing global translational regulation.

33 o the model are reliable candidates for post-translational regulation.

34 known to be involved in transcriptional and translational regulation.

35 ate with the 3'UTR, which may have a role in translational regulation.

36 transcriptional, translational, and/or post-translational regulation.

37 new insights into mechanisms of plant virus translational regulation.

38 nscriptional, post-transcriptional, and post-translational regulation.

39 tal retardation-related protein 1 (FXR1) for translational regulation.

40 the rs4803217 allele modulates the extent of translational regulation.

41 are found in nature, and their role in post-translational regulation.

42 intersecting with metabotropic signaling and translational regulation.

43 es a human prolyl hydroxylase with a role in translational regulation.

44 Instead, our data suggest a complex role in translational regulation.

45 to identify patterns of transcriptional and translational regulation across different organisms and

46 rmatogenic cell-specific transcriptional and translational regulation and a novel cellular function i

47 e protein kinase, plays an important role in translational regulation and cell survival.

48 t systems to dissect mechanisms of mammalian translational regulation and continue to offer insight i

49 gies that seek to address the alterations in translational regulation and energy metabolism that char

50 However, how eIF3a participates in translational regulation and in formation of the eIF3(a:

51 induced eIF4B phosphorylation is involved in translational regulation and is required for optimal KSH

52 rols neuronal morphogenesis by mediating the translational regulation and localization of a large num

53 t, they are powerful tools for investigating translational regulation and probing ribosome structure.

54 in the mitochondrion for functional mitomiR translational regulation and provide a connecting link b

55 e, the 3'UTR of EBF2 is sufficient to confer translational regulation and required for the proper act

56 XR1 is a multifunctional protein involved in translational regulation and stabilization of its mRNA t

57 PDZ domain of GIPC is essential for the post-translational regulation and the binding of IGF-IR.

58 However, the mechanisms of translational regulation and the roles of translation fa

59 s, protein localization, protein metabolism, translational regulation and vesicle mediated transport

60 ially controlled through Notch-mediated post-translational regulation and we demonstrate that the for

61 pression of somatic proteins at the level of translational regulation, and by (2) functioning with CS

62 obe cell type-specific transcriptomes, study translational regulation, and probe ribosome binding of

63 drial-related functions, transcriptional and translational regulation, and signaling pathways.

64 unique role for actin-associated proteins in translational regulation, and suggest that mRNA-specific

65 Our data establish a role for MCT-1 in translational regulation, and support a linkage between

66 that TRAP is an effective means for studying translational regulation, and that several nuclear-encod

67 Oncogenic potential is associated with translational regulation, and the prevailing view is tha

68 tivated during mitotic entry by proteolysis, translational regulation, and transcriptional regulation

69 Certain forms of translational regulation, and translation itself, rely o

70 Two of these classic examples of translational regulation are discussed before taking up

71 genes and studying their transcriptional and translational regulation are key steps to understanding

72 mechanisms of CD39 transcriptional and post-translational regulation are not well known.

73 identified ~200 mRNAs that undergo specific translational regulation at mitotic entry.

74 tegies that take advantage of differences in translational regulation between normal and tumor cells.

75 iversal due to post-transcriptional and post-translational regulation, both of which are highly preva

76 ple tasks in mRNA processing, transport, and translational regulation, but it also forms aggregates i

77 t summation of complex positive and negative translational regulation by 3' UTR-binding proteins, wit

78 to provide a physiological context for this translational regulation by ascribing defined functions

79 ndings provide a new mechanism for TDP1 post-translational regulation by ATM and DNA-PK.

80 We investigated combinatorial translational regulation by Drosophila Pumilio (Pum) and

81 nscript are necessary but not sufficient for translational regulation by eif3ha.

82 Bioinformatic analyses suggest that translational regulation by FMRP and transcriptional cor

83 regulates synaptic plasticity, and its local translational regulation by fragile X mental retardation

84 romiscuous phosphorylation and the attendant translational regulation by heterologous kinases, wherea

85 Coordinated translational regulation by hnRNP E1 constitutes a post-

86 es in the liver of rats indicating a lack of translational regulation by low iron levels.

87 Translational regulation by miRNAs may represent a commo

88 Translational regulation by oncogenic proteins may be a

89 Thus, in addition to gene expression, translational regulation by p38 MAPK could be a novel me

90 The molecular basis of this translational regulation by RA/RARalpha signaling, howev

91 ) of human p53 mRNA that is critical for its translational regulation by RPL26.

92 Thus, translational regulation by TGF-beta at the elongation s

93 Both transcriptional and post-translational regulation can affect protein abundance an

94 ate how the interplay of transcriptional and translational regulation can be exploited to control the

95 In addition, we found that cytoplasmic translational regulation can precede nuclear transcripti

96 Translational regulation contributes to plasticity in me

97 We conclude that translational regulation controls physiological levels o

98 demonstrates that nutrient availability and translational regulation controls protein and small pept

99 Finally, translational regulation correlates positively with long

100 a have indicated that defects in cancer cell translational regulation could be one area that may be e

101 otably, the mRNA features that contribute to translational regulation could not fully explain the var

102 Our findings also demonstrate that translational regulation could play a critical role in t

103 lar functions, including transcriptional and translational regulation, DNA repair, drug resistance, a

104 es, has implicated it in transcriptional and translational regulation, DNA replication and repair, an

105 However, the importance of translational regulation during mitosis remains poorly u

106 ting responses to ozone were used to examine translational regulation during ozone stress.

107 study we have investigated the occurrence of translational regulations during light stress in Arabido

108 In contrast, our understanding of how translational regulation evolves has lagged far behind.

109 tumor systems and supports the role of post-translational regulation for the implemented EGFR pathwa

110 dies have highlighted the importance of post-translational regulations for the parasite's progression

111 ad habits carried over from older studies of translational regulation, here illustrated by discussing

112 Any mutation at Glu49 or Asp83 blocked translational regulation; however, only a subset of thes

113 e participation of the GCN2-IMPACT module of translational regulation in a highly controlled step in

114 chemical demonstration, to our knowledge, of translational regulation in a T box riboswitch.

115 a critical process in protein synthesis, but translational regulation in antigen-specific T cells in

116 cating that additional factors contribute to translational regulation in Arabidopsis.

117 derstanding of post-transcriptional and post-translational regulation in attaching and effacing patho

118 t al identify MYC as an important target for translational regulation in chronic lymphocytic leukemia

119 Differences in mechanisms of translational regulation in CLL and normal B cells may p

120 rotein kinase LimK1; this is a novel form of translational regulation in dendrites and may have impor

121 les illustrating the critical role played by translational regulation in determining the expression l

122 Some popular ideas about translational regulation in eukaryotes have been recogni

123 esults demonstrate a role for 3'UTR mediated translational regulation in fine-tuning the temporal exp

124 ly(A) switching of e(r) provides a means for translational regulation in germ cells.

125 SunTag should be broadly applicable to study translational regulation in live single cells.

126 enrichment in P-bodies and eIF4E-binding in translational regulation in mammalian cells.

127 nificance of protein diversification through translational regulation in mammals is largely unexplore

128 ntification of the CEBPB gene as a target of translational regulation in myeloid precursor cells tran

129 ate MNK1 as a key component of BDNF-mediated translational regulation in neurons.

130 To decipher the molecular basis of translational regulation in photomorphogenic Arabidopsis

131 ranscriptional coregulation is the selective translational regulation in response to growth condition

132 d that a spectrum of mRNAs undergo different translational regulation in the fasted state.

133 hat SHH might have evolved more complex post-translational regulation in the lineage leading to human

134 liver tissues to investigate strain-specific translational regulation in the spontaneously hypertensi

135 To investigate translational regulation in this system, we developed a

136 To understand translational regulation in this system, we systematical

137 The importance of translational regulation in tumour biology is increasing

138 r, these results uncovered critical roles of translational regulations in controlling appropriate gen

139 Translational regulation is an essential part of cancer

140 Translational regulation is critical in cancer developme

141 FP reporter over-expression show that RNP-4F translational regulation is highly sensitive in the deve

142 The biological importance of this translational regulation is immense, and affects such pr

143 This translational regulation is implicated for many key regu

144 circuitry, suggesting that the scheduling of translational regulation is organized by the same cyclic

145 scriptionally primed to generate neurons but translational regulation maintains these precursors in a

146 ecific transcripts suggests that competitive translational regulation may account for the synthesis o

147 addition to transcriptional regulation, post-translational regulation may also control HSC differenti

148 teins, and highlighting the possibility that translational regulation may be a particularly common fu

149 he translational level and also suggest that translational regulation may play an important role in t

150 In addition, translational regulation may provide an additional layer

151 ther, our results demonstrate a ligand-gated translational regulation mechanism mediated by a non-gen

152 In addition, we characterized a post-translational regulation mechanism of FadD33 by the myco

153 d stabilization of MKP1 demonstrate the post-translational regulation of a plant MKP in vivo, adding

154 ses that are fundamental enzymes in the post-translational regulation of ABCG1 and ABCG4 protein leve

155 several studies, and we have also shown that translational regulation of AQP4 by miR-320a could prove

156 e pathway, and is dependent on S6K1-mediated translational regulation of B7-H1 protein.

157 ave recently identified a novel form of post-translational regulation of BACE1 (beta-site amyloid pre

158 the bone marrow through Rab5-dependent post-translational regulation of beta1/beta2 integrins.

159 We identified translational regulation of BMPRII expression and the co

160 icate that Smt1p is likely to be involved in translational regulation of both mRNAs.

161 mRNA levels or protein stability, suggesting translational regulation of C/EBPbeta.

162 nd calreticulin, have been implicated in the translational regulation of C/EBPbeta.

163 es mitotic arrest in male germ cells through translational regulation of cell cycle genes.

164 However, post-translational regulation of cGAS remains largely unknown

165 ng of ribosome footprints on RNAs to explore translational regulation of coding and noncoding RNAs in

166 Negative translational regulation of CPA1 occurs when the nascent

167 s reveal a critical mechanism underlying the translational regulation of CRC metastatic progression,

168 A, supporting the critical role for the post-translational regulation of cyclin D1 in response to DNA

169 of additional regulatory elements during the translational regulation of DPP.

170 n, we provide here a novel mechanism of post-translational regulation of dysbindin and hypertrophy vi

171 Importantly, this translational regulation of EAAT2 occurred in vivo (i.e.

172 Transcript-selective translational regulation of epithelial-mesenchymal trans

173 g important roles for translational and post-translational regulation of ESC fate.

174 Post-transcriptional and post-translational regulation of factors that determine skin

175 t encodes a transmembrane receptor, but post-translational regulation of Fat has not been described.

176 However, the post-translational regulation of Fn14 expression has not been

177 In neurons, translational regulation of gene expression has been imp

178 ed polysome profiling by RNA-Seq to quantify translational regulation of gene expression in a recentl

179 probably function in the transcriptional and translational regulation of gene expression in haploid s

180 roRNAs has revealed novel mechanisms of post-translational regulation of gene expression, the implica

181 proteins, contributes along with FsrA to the translational regulation of gene expression.

182 motifs and miRNA expression associated with translational regulation of gene expression.

183 This review will provide an overview of the translational regulation of globin mRNAs and integrated

184 the adult neural stem cell fate through the translational regulation of glycogen synthase kinase 3be

185 n of 14-3-3 is the first description of post-translational regulation of GPSM3 subcellular localizati

186 are established through the localization and translational regulation of gurken (grk) mRNA.

187 ing by Arabidopsis SPA1 likely involves post-translational regulation of HFR1 protein accumulation.

188 Although transcriptional and translational regulation of HMW and LMW FGF-2 has been e

189 or completely (Hsp33-Y12E) abolish this post-translational regulation of Hsp33 chaperone function.

190 d HSPA5 ubiquitination and suggest that post-translational regulation of HSPA5 protein is critical fo

191 de ribosome profiling, we uncover widespread translational regulation of hundreds of mRNAs serving as

192 The impact of post-translational regulation of HuR and resulting cellular e

193 Translational regulation of IBTKalpha mRNA involves stre

194 en hyper- and hypo-phosphorylated 4E-BP1 and translational regulation of Id1 expression.

195 or the serine-threonine phosphatase PPM1G in translational regulation of Id1 protein expression.

196 ics, and CPEB, a protein that is involved in translational regulation of important cell cycle regulat

197 Studies on the post-translational regulation of IRF-1 have been hampered by

198 her iron- and oxygen-dependent mechanism for translational regulation of its expression via iron regu

199 Here we report a dynamic, post-translational regulation of its kinase activity that is

200 The experiments revealed extensive translational regulation of key biological processes.

201 ist, Fulvestrant 182,780 suggesting a direct translational regulation of Kir4.1 and glutamate transpo

202 These data show that post-translational regulation of L1 retrotransposons plays a

203 Together, our data demonstrate that translational regulation of LLO is critical for L. monoc

204 ndrome occur as well - microRNAs involved in translational regulation of major synaptic proteins; sca

205 Translational regulation of maternal mRNAs in distinct t

206 Here, we characterize the translational regulation of maternally supplied mom-2 mR

207 Our data conclude an essential post-translational regulation of MLL by the cell cycle ubiqui

208 This identified unexpected and pervasive translational regulation of most of the core signalling

209 raise the possibility that localization and translational regulation of mRNAs at the ER plays a role

210 To gain insight into the translational regulation of mRNAs during nodule formatio

211 regulate sleep by affecting stabilization or translational regulation of mRNAs.

212 ve found that PDHK4 plays a role in the post-translational regulation of mutant KRAS activity.

213 morphogenesis that highlights exquisite post-translational regulation of mVEGFR1 in its role as a mol

214 ssible sites are critically involved in post-translational regulation of N-type Ca(2+) channels by NO

215 Summary Post-translational regulation of nitrogen fixation, or switch

216 Our results imply that translational regulation of nuclear-encoded mitochondria

217 These experiments examine translational regulation of ODC in RIE-1 cells, comparin

218 were mediated through transcriptional and/or translational regulation of OPN, smooth muscle cells sti

219 n of gurken mRNA as well as localization and translational regulation of oskar mRNA.

220 there has been growing interest in the post-translational regulation of P-type ATPases by protein ki

221 Thus, translational regulation of p53 mRNA and cellular senesc

222 In this review, we will focus on the translational regulation of p53 through the 5'- and 3'-u

223 se neurodegeneration by interfering with the translational regulation of particular mRNAs.

224 Translational regulation of PB1-F2 expression was partia

225 y early sleep-wake onset due to altered post-translational regulation of period homolog 2 (PER2).

226 ly nothing is presently known about the post-translational regulation of plant MKPs in vivo.

227 Here the authors report that the post-translational regulation of PRC1 components CBX4 and CBX

228 ional proANP, suggesting effects on the post-translational regulation of proBNP.

229 Although its contribution in translational regulation of proline repeat-rich proteins

230 ing evidence is emerging for additional post-translational regulation of proneural protein activity.

231 tty acids is a mechanism for reversible post-translational regulation of protein function by nitro-fa

232 , we discuss recent advances concerning post-translational regulation of PTEN in general, and in more

233 synthesis suggests an intrinsic role for the translational regulation of rat Mrp2 protein.

234 A striking example is the S phase translational regulation of RICTOR, which is associated

235 urther show that both translational and post-translational regulation of RpoS contribute to peroxide

236 Runx2 during development as well as the post-translational regulation of Runx2 through modification b

237 e data reveal novel mechanisms by which post-translational regulation of Scw can modulate Dpp signali

238 RNA-binding protein that is involved in the translational regulation of several neuronal mRNAs.

239 1 transcription precedes EMT induction, post-translational regulation of Snail1 is also critical for

240 In contrast, post-transcriptional and post-translational regulation of some enzymes appears to cont

241 se of stromal transcriptional and epithelial translational regulation of some SC marker gene expressi

242 is a DEAD-box RNA helicase that functions in translational regulation of specific mRNAs.

243 RNA-binding protein that is required for the translational regulation of specific target mRNAs.

244 In addition, transcriptional and post-translational regulation of SsOGT by DNA damage was stud

245 ribosome profiling further reveals potential translational regulation of stress response genes.

246 lity and also have elements required for the translational regulation of TCR zeta chain expression in

247 ependent protein kinase, PKR, is involved in translational regulation of TCTP.

248 ent in the 5' untranslated region allows for translational regulation of TFPIbeta expression.

249 Our findings suggest that post-translational regulation of the BI-1 protein by E3 ligas

250 This unusual poise enables gradual post-translational regulation of the BiP chaperone cycle and

251 Translational regulation of the dendritically localized

252 We propose a modified model for post-translational regulation of the Drosophila clock, in whi

253 is required for the correct localization and translational regulation of the grk message.

254 ification of the Mdm2 locus or aberrant post-translational regulation of the Mdm2 protein.

255 However, the mechanisms underlying translational regulation of the p53 protein in response

256 Together, these findings suggest that post-translational regulation of the Thr(567) in the MT1-MMP

257 in Hedgehog (Hh) signal transduction is post-translational regulation of the transcription factor, Cu

258 Here, we show that post-translational regulation of the transcription factors ET

259 To explore mechanisms involved in the post-translational regulation of the transporter, we have use

260 novel mechanism for mTORC1 kinase-dependent translational regulation of the voltage-gated potassium

261 le in Cox1 biogenesis, COX assembly, and the translational regulation of these processes.

262 be an important contributor to Akt-mediated translational regulation of these transcripts in murine

263 rms of FOXP2 may provide mechanisms for post-translational regulation of transcription factor functio

264 Post-translational regulation of transcription factors is oft

265 The transcriptional and translational regulations of gene expression by the micr

266 structures provide detailed insight into the translational regulation on the bacterial ribosome by mR

267 Translational regulation only occurred in the presence o

268 er RNA levels in young tissue, suggestive of translational regulation or altered protein stability.

269 ve length of the 3'UTR and may be related to translational regulation or ribosome recycling, for whic

270 criptional regulation, alternative splicing, translational regulation, phosphorylation and other post

271 minated the prevalence and dynamic nature of translational regulation pivotal to physiological adapta

272 sufficient for germline determination, with translational regulation playing a key role in the proce

273 rol of Nrf2 has been largely studied at post-translational regulation points by Keap1.

274 We further show that translational regulation preferentially targets genes in

275 However, its post-translational regulation remains elusive.

276 d is unknown and the role of Ago proteins in translational regulation remains elusive.

277 However, HAdV translational regulation remains relatively uncharacteri

278 This translational regulation results from activation by TGF-

279 o identify sequence features responsible for translational regulation, ribosome loading values and fe

280 a non-coding RNA that has been implicated in translational regulation, seizure, and anxiety.

281 lation ontology captures transcriptional and translational regulation, substrate-level regulation of

282 chemical network given no transcriptional or translational regulation that can be used to explore the

283 opments in the fields of innate immunity and translational regulation that may help explain mechanism

284 these indicate widespread prevalence of post-translational regulation that may segregate the activiti

285 of regulation, including transcriptional and translational regulation, that drive core biological pro

286 logical behaviour, and linking rRNA-mediated translational regulation to modulation of lifespan, and

287 t system under anaerobic conditions and adds translational regulation to the ArcA-ArcB regulon.

288 Our results link genome evolution and translational regulation to the long-term persistence of

289 ession in this embryo is restricted early by translational regulation to the small micromere lineage.

290 ansporters are subject to many forms of post-translational regulation typically associated with recep

291 ome footprints (RFs) on mRNAs to investigate translational regulation under control and sublethal hyp

292 interactions such as signal transduction and translational regulation under physiological conditions.

293 uminate the prevalence and dynamic nature of translational regulation underlying the mammalian cell c

294 Despite high G+C content, translational regulation was not evident by the mammalia

295 to be involved in beta-catenin mRNA (CTNNB1) translational regulation, was controlled by HSF1 repress

296 Mutations that block translational regulation were isolated throughout the N-

297 ve IRESs have created a confusing picture of translational regulation which is not helpful when tryin

298 MRP's canonical functions in RNA binding and translational regulation, which are traditionally associ

299 isoforms there are clear differences in post-translational regulation, which contribute to difference

300 for assessing the significance of changes in translational regulation within cells and between condit