ライフサイエンスコーパス: translational research

1 disease, and an embracing of the concept of 'translational research'.

2 tion in the context of increased emphasis on translational research.

3 program is necessary to ensure leadership in translational research.

4 ell lines to provide renewable resources for translational research.

5 amework for further clinical and preclinical translational research.

6 man pain processing is crucial for improving translational research.

7 ith drugs/compounds for drug repurposing and translational research.

8 uires increased funding for basic as well as translational research.

9 ability may be a limiting factor for further translational research.

10 peutic interest is of prime significance for translational research.

11 erspective, and leadership to the process of translational research.

12 as well as integration of clinical data into translational research.

13 te early neuropathology and aging effects in translational research.

14 n broad applications for MM-401 in basic and translational research.

15 ard tests jeopardizes accurate diagnosis and translational research.

16 onse rate (RR), safety, quality of life, and translational research.

17 mechanisms of PNDM but have limitations for translational research.

18 as prerequisites to progress in this area of translational research.

19 trong potential to accelerate both basic and translational research.

20 cluded response rate, safety assessment, and translational research.

21 address these issues that are pertinent for translational research.

22 n culture and open new avenues for basic and translational research.

23 tudies are essential to provide traction for translational research.

24 ta2* nAChRs in various CNS disorders and for translational research.

25 se to treatment is expanding in clinical and translational research.

26 nment has become a lively successful area of translational research.

27 making the NPU-threat test an ideal tool for translational research.

28 support of hospital-based interdisciplinary translational research.

29 odifications with important implications for translational research.

30 d resilience frameworks that guide basic and translational research.

31 e clinical success are a key area of current translational research.

32 rich training to learn the joy and agony of translational research.

33 outcome and leads to actionable findings for translational research.

34 senting new opportunities and challenges for translational research.

35 re collective action to facilitate basic and translational research.

36 odel systems in areas spanning from basic to translational research.

37 the basic sciences as the starting point of translational research.

38 ) or induced pluripotent stem (iPS) cells in translational research.

39 lity of human hemato-lymphoid-system mice in translational research.

40 eurological and psychiatric diseases through translational research.

41 immune responses in humans, thus empowering translational research.

42 and lead to increased funding for basic and translational research.

43 erged as a frontier for both fundamental and translational research.

44 ingly important objective for biological and translational research.

45 form for xenograft mouse models in basic and translational research.

46 strating the utility of these biomarkers for translational research.

47 ific targets on B cells an important area of translational research.

48 ng analytical chemists at the front lines of translational research.

49 h desired activity for use in both basic and translational research.

50 have provided many new avenues for basic and translational research.

51 s and research funders are investing more in translational research.

52 opment of follow-up studies and evidence for translational research.

53 knowledge on natural history and facilitate translational research.

54 tion of surgeon-scientists to the success of translational research.

55 ed the way we approach problems in basic and translational research.

56 rovided the framework for emerging basic and translational research.

57 testine and provides new tools for basic and translational research.

58 ous human cells are widely used in basic and translational research.

59 animal models and human patients to improve translational research.

60 and their identification is fundamental for translational research.

61 geneity to enhance precision in clinical and translational research.

62 addressed with targeted epidemiological and translational research.

63 rate, safety, patient-reported outcomes, and translational research.

64 rendering them useful as an animal model in translational research.

65 nd future applications of PSCs for basic and translational research.

66 and is an invaluable resource for improving translational research.

67 foundation for evolutionary, functional, and translational research.

68 ith animal models would be of great value in translational research.

69 in the human embryo and fetus is crucial for translational research.

70 ble and controllable hPSC culture routine in translational research.

71 including exposure to cutting-edge clinical/translational research, access to some of the best scien

72 to advance understanding of human diseases, translational research across rodents and humans on stre

73 n a human tumor and give insights needed for translational research aimed at boosting human immunity

74 ories both in terms of basic research and in translational research aimed at increasing plant perform

75 gap in knowledge is a serious impediment to translational research aimed at understanding brain deve

76 ulation of globin genes is a primary goal of translational research aimed toward hemoglobinopathies.

77 What is advocated instead is "translational" research aimed directly at treating disea

78 MART has a wide range of functionalities for translational research and a large user community, but i

79 s" provide novel capsid sequences for use in translational research and clinical applications.

80 ves from nuclease degradation is crucial for translational research and clinical diagnostics.

81 used knowledgebase for the support of cancer translational research and drug discovery.

82 ed knowledgebase developed to support cancer translational research and drug discovery.

83 ograms that range from basic neuroscience to translational research and finally clinical research to

84 a dependable genomic diagnosis platform for translational research and for the clinical management o

85 d Public Health's Institute for Clinical and Translational Research and Health Innovation Program.

86 addresses an important challenge in current translational research and justifies further development

87 us research clearly demonstrate insufficient translational research and limited investment in diagnos

88 d in the Irish Centre for Fetal and Neonatal Translational Research and partly supported by Science F

89 Planned translational research and pharmacogenomic analyses of t

90 provide long-term support to the field, from translational research and regulation to professional ed

91 lish disease models, and provide a basis for translational research and testing of novel therapeutics

92 ithin a common framework and thereby enables translational research and the development of medical ap

93 cting evidence derived from clinical trials, translational research, and basic science demands that i

94 Significant advances in molecular biology, translational research, and clinical reports are detaile

95 anisms of these disorders, through basic and translational research, and in targeting the receptors o

96 echnique is now widely employed in basic and translational research, and increasingly is also used pr

97 tions of DHS analysis both for basic and for translational research, and may provide critical informa

98 nvened of world experts in immunology, human translational research, and positron emission tomographi

99 cusing on the use of ontologies in basic and translational research, and we demonstrate how research

100 aming patient waveform data for clinical and translational research, and will advance the study and m

101 An interdisciplinary, bench to bedside translational research approach is crucial for the succe

102 d to be addressed by a multidisciplinary and translational research approach to develop novel therapi

103 n the nonhuman primate (NHP) is valuable for translational research approaches in humans.

104 Advances in translational research are often driven by new technolog

105 Data from continuing clinical and translational research are urgently needed to improve, a

106 A (exome-seq) has become common in basic and translational research as a means of interrogating the i

107 immune system represent a promising tool for translational research as they may allow modeling and th

108 In particular, the terms basic research and translational research as used today in biomedicine seem

109 enormous benefit for both basic science and translational research because over 98% of the human gen

110 Translational research between human and non-human prima

111 next-generation sequence-variation data, and translational research, but a comparable resource has no

112 overy in developmental biology as well as in translational research, but whether organoids can truly

113 zure taxonomy will guide future modeling and translational research by identifying universal rules go

114 New advances in translational research can be expected to heighten the i

115 ge about how new insights from discovery and translational research can yield measurable, population-

116 Part One includes the sections: Basic & Translational Research, Cardiac Failure, Cardiomyopathie

117 Part One included the sections: Basic & Translational Research, Cardiac Failure, Cardiomyopathie

118 ation of surgeons in basic science research, translational research, clinical outcomes research, and

119 rrelated with distant recurrence in both the translational research cohort within the Arimidex, Tamox

120 researchers within both discovery-based and translational research communities.

121 orts of investigators working throughout the translational research continuum from basic science to p

122 accelerating cancer epidemiology across the translational research continuum in the 21st century: em

123 e we offer a Perspective on how a productive translational research dialog between preclinical models

124 s and to describe the results of preclinical translational research directed toward urologic applicat

125 ve malignancy the focus of a large concerted translational research effort.

126 children with AVD and is to explore ongoing translational research efforts.

127 gress has been made in the implementation of translational research, even for more common disorders i

128 We present 3 lines of translational research evidence, extracted from a compre

129 l, this receptor is an attractive target for translational research: existing drugs with established

130 e amounts of data across basic, clinical and translational research fields.

131 we review the most current basic science and translational research findings on several of the most c

132 ed with small and large animal models with a translational research focus.

133 n unprecedented model organism for basic and translational research focusing on the biology of the so

134 in models other than rodents, especially for translational research for human cellular therapy.

135 acilitate the use of the laboratory mouse in translational research for human health and disease, hel

136 e disease of the skin, has been the focus of translational research for over 30 years, and both melan

137 erventions-and T2 translational research, or translational research for public health.

138 irst, we emphasize the importance of reverse translational research for understanding chronic pain-th

139 Translational research frequently fails to replicate in

140 ns, providing examples and opportunities for translational research from community surveys and prospe

141 Translational research generally refers to the applicati

142 National Ovarian Cancer Coalition Dream Team Translational Research Grant, and V Foundation Translati

143 A great wealth of preclinical and translational research has been and is currently being d

144 Translational research has identified a significant prop

145 Translational research has validated platelet-derived gr

146 e, recent advances in the field of basic and translational research have enhanced our understanding o

147 able, significant advances in both basic and translational research have enhanced understanding of di

148 Translational research hinges on the ability to make obs

149 ing platform that enables the development of translational research hypotheses based on comparative g

150 ing platform that enables the development of translational research hypotheses based on comparative g

151 human disease and enable the development of translational research hypotheses based on comparative g

152 In the era of targeted therapy for cancer, translational research identifying molecular targets in

153 t transformation and potentially facilitates translational research in a monocot model plant.

154 bstacles that need to be overcome to advance translational research in and tumor heterogeneity.

155 opted to accelerate scientific discovery and translational research in bio-nano science.

156 tween 2007 and 2009 and were enrolled in the Translational Research in Biomarker Endpoints in AKI coh

157 These models may help to accelerate translational research in cancer biology and tissue engi

158 models have substantial utility in basic and translational research in cancer biology; however, study

159 o experiments, genetic analysis and clinical-translational research in cardiac neonatal lupus reveal

160 urred during a watershed period of basic and translational research in glycation that encompassed new

161 To close these gaps in knowledge, translational research in humans is a critical next step

162 tabolic phenotyping is an expanding field of translational research in medicine, focusing on the iden

163 lso highlighted the ongoing challenges about translational research in melanoma, including availabili

164 scuss gaps and opportunities in clinical and translational research in metastatic breast cancer.

165 y potential biomarkers, an important goal of translational research in neurodegeneration.

166 sed, open-label phase 3 KRISTINE trial in 68 Translational Research In Oncology centres (hospitals an

167 egorizations of HER2 by FISH status in BCIRG/Translational Research in Oncology trials.

168 n fear extinction could serve as a model for translational research in other areas of behavioral neur

169 hat neuroeconomics is a potential bridge for translational research in psychiatry for several reasons

170 o give a perspective for future clinical and translational research in renal cell carcinoma.

171 al SpA is the most rapidly expanding area of translational research in SpA.

172 o a broader social framework about so-called translational research in specific and the root causes o

173 will serve as a significant advancement for translational research in the areas of metabolic liver d

174 suitable genetic model has impaired further translational research in the field.

175 ork approaches are particularly relevant for translational research in the neurodegenerative disorder

176 ering strategies, increasing the options for translational research in the vector control field.

177 ore likely to promote translational and post-translational research in tomato and additional species,

178 ignificant power in International Genetics & Translational Research in Transplantation Network to det

179 e and design of the International Genetics & Translational Research in Transplantation Network.

180 Translational research in trials combining Vitamin D and

181 c disorders, and there is little evidence of translational research including treatment outcomes.

182 of basic cancer biology and the promotion of translational research, including drug discovery and dru

183 d cell adhesion and migration as well as for translational research, including targeted intervention

184 Translational research informed by clinical observations

185 The study was conducted at the Translational Research Institute for Metabolism and Diab

186 ight gained using these models is empowering translational research into human disease.

187 8 medium that serves as a tool for basic and translational research into human pluripotent stem cells

188 brain function and improve our capacity for translational research into neurological disorders.

189 ccessibility in humans have slowed basic and translational research into renal development and diseas

190 or the acceleration of human stem cell-based translational research into the causes and potential tre

191 This model is therefore a useful tool for translational research into the pathophysiology of ventr

192 The Translational Research Investigating Biomarker Endpoints

193 Using samples from the Translational Research Investigating Biomarker Endpoints

194 The TRIUMPH study (Translational Research Investigating Underlying Disparit

195 I patients from 24 hospitals enrolled in the Translational Research Investigating Underlying disparit

196 treated at 24 hospitals participating in the Translational Research Investigating Underlying Disparit

197 Data from the 24-center TRIUMPH (Translational Research Investigating Underlying Disparit

198 etic subgroups of 2 independent cohorts, the Translational Research Investigating Underlying Disparit

199 I from 24 US centers into the TRIUMPH study (Translational Research Investigating Underlying Disparit

200 s and has wider interest for fundamental and translational research involving exosomes.

201 Translational research involving genomics, microRNA, pro

202 e of autism as a diagnostic category guiding translational research is fraught with so many problems

203 Translational research is key to bridging the gaps betwe

204 huge public health gains, while support for translational research is leading to the development of

205 However, before clinical applications, much translational research is necessary to ensure that their

206 Further translational research is needed to optimize ways of inh

207 Further translational research is required to improve our unders

208 The current emphasis on translational research is starting to blur differences b

209 Translational research is supported by RGD's comparative

210 The term translational research is typically used to refer both t

211 Basic and translational research is urgently needed to clarify pat

212 Further translational research is warranted.

213 clinically viable, and further clinical and translational research is warranted.

214 With the resurgence of translational research, it is useful to examine some of

215 the potential to provide profound impacts on translational research, leading to the more rapid develo

216 ntext of recent progress in metabolomics and translational research methodologies.

217 cept of translational physiology applies the translational research model to the physiological scienc

218 nce of combination studies both in basic and translational research necessitates a method that can be

219 multiple hPSC sources and hence addresses a translational research need.

220 In translational research, NINDS is taking the lead on the

221 ein we provide our perspective regarding the translational research objectives of this infection that

222 Recent progress in the translational research of echinocandins has led to new a

223 Translational research of immunohistochemistry protein a

224 The result has important implication to the translational research of microarray as a practical dise

225 in patient risk profiling and for informing translational research of potential gene targets and med

226 vel rat NK cell subset may facilitate future translational research of the role of distinct NK cell s

227 occurred in the past 5-10 years in clinical translational research of thyroid cancer.

228 hared platform for developmental biology and translational research, offering innovative methods for

229 cell biologists to venture into the realm of translational research on a regular basis, we would like

230 ore than USD800 million to support basic and translational research on antimicrobials, more than USD2

231 lighted important areas of current basic and translational research on biliary epithelial cell biolog

232 icle reviews and highlights past and current translational research on SMA therapeutics.

233 In this meeting, translational research on stem cells for disease modelin

234 Indeed, the successful translational research on the ER was the catalyst for th

235 ect targets not exploited by current agents, translational research on the significance of imaging th

236 ely links areas of research (i.e., basic and translational research, or clinical research and impleme

237 ely links areas of research (i.e., basic and translational research, or clinical research and impleme

238 cience results into new interventions-and T2 translational research, or translational research for pu

239 likelihood of funding success: clinical and translational research, outcomes and effectiveness resea

240 e network illustrate the potential impact on translational research, particularly for studies involvi

241 and vestibular rehabilitation from a unified translational research perspective.

242 ere have been enormous advances in basic and translational research pertaining to TSC.

243 This work establishes an open-source translational research platform for genome-wide associat

244 nd research should be conducted according to translational research principles in which preclinical r

245 hat we consider particularly promising for a translational research program aimed at furthering our u

246 t loss combinations that have emerged in our translational research program aimed at identifying natu

247 is an academically based, multidisciplinary, translational research program that for 25 years has sou

248 989); and the Leukemia and Lymphoma Society (Translational Research Program).

249 03532-03), and Leukemia and Lymphoma Society Translational Research Program.

250 Many gut peptides are now in translational research programmes to investigate their p

251 specialist clinical services integrated with translational research programmes, but also by joining u

252 ites, thereby contributing to both basic and translational research programs.

253 -time biopsies are valuable for clinical and translational research purposes, providing insight in ri

254 discuss recent progress in experimental and translational research related to surgical repair of pro

255 onducted to focus on the recent clinical and translational research related to the associations betwe

256 CO's Blueprint for Transforming Clinical and Translational Research, released in November, calls for

257 isease has been proposed, its application in translational research remains limited.

258 Ongoing translational research seeks to identify the most scient

259 scale analysis of the human immune system in translational research settings.

260 Translational research spanning the past few decades has

261 Recent basic and translational research studies have significantly improv

262 We review clinical and translational research studies of HF in congenital heart

263 with an emphasis on targeted preclinical and translational research studies published over the past 2

264 iomarkers and multimodality imaging in early translational research studies.

265 tions of these findings for future basic and translational research studies.

266 This translational research suggests that some genetic influe

267 , to the point where we now have 4 stages of translational research (T0-T4).

268 erapies represent a culmination of basic and translational research that actually spans many decades.

269 pective on emerging scientific approaches in translational research that can enhance the progress in

270 late this knowledge into clinical trials and translational research that can result in public health

271 genesis of autoimmune diseases is an area of translational research that encompasses many fields.

272 es is an exciting, rapidly advancing area of translational research that has already entered the clin

273 ries in NK-cell receptor biology have fueled translational research that has led to remarkable result

274 We summarize recent advances in translational research that hold promise for the progres

275 ults indicate in a model highly pertinent to translational research that neuronal IGF resistance may

276 te; Johns Hopkins Institute for Clinical and Translational Research; the SAILS trial was also support

277 ment, and it will illustrate how some of the translational research therapies have already entered th

278 nd researchers are an important component of translational research to address obesity.

279 ere is a critical need for interdisciplinary translational research to connect dyspnea mechanisms wit

280 Translational research to develop novel therapeutics aga

281 tructure-function analyses, and would direct translational research to pathways most likely to benefi

282 erspective to stimulate basic, clinical, and translational research to understand how the aging proce

283 orphogenesis offers grounds for optimism for translational research toward intervention in human morp

284 ients with TSC, the application of basic and translational research towards a specific clinical disor

285 Recent emphasis on translational research (TR) is highlighting the role of

286 ext mining fall both into the category of T1 translational research-translating basic science results

287 These are elegant examples of translational research: understanding basic physiology i

288 The outcome of this translational research unequivocally revealed the cellul

289 models are poised to realise the promise of translational research via clinical applications such as

290 Translational research was planned to correlate the expr

291 The term 'translational research' was coined 20 years ago and has

292 h PBMC carry many theoretical advantages for translational research, we have found that sample hetero

293 Disease, population, and translational research were intermediate, and few respon

294 provide an ideal starting point for further translational research where the results can be combined

295 from ongoing prospective clinical trials and translational research will help clarify whether anesthe

296 Ongoing translational research will inevitably have a major impa

297 It is expected that improved translational research will lead to optimized therapy an

298 The increased efforts in translational research will result in earlier diagnosis

299 have delivered high-impact contributions in translational research, with associated pharmaceutical p

300 Cardiac experimental biology and translational research would benefit from an in vitro su