ライフサイエンスコーパス: transmembrane conductance regulator

1 tide-binding domain from the cystic fibrosis transmembrane conductance regulator.

2 en through activation of the cystic fibrosis transmembrane conductance regulator.

3 lesser effects on misfolded cystic fibrosis transmembrane conductance regulator.

4 ction in the gene coding for cystic fibrosis transmembrane conductance regulator.

5 stance arteries ex vivo, the cystic fibrosis transmembrane conductance regulator (1) is critical for

6 nger regulatory factor-1 and cystic fibrosis transmembrane conductance regulator (a key player in the

7 psin-controlling gene or the cystic fibrosis transmembrane conductance regulator); a few patients hav

8 Because the cystic fibrosis transmembrane conductance regulator (ABCC7) is closely r

9 ctor-alpha downregulates the cystic fibrosis transmembrane conductance regulator across several organ

10 cells via a reduction in the cystic fibrosis transmembrane conductance regulator activity and biosynt

11 essure resulted in decreased cystic fibrosis transmembrane conductance regulator activity and liquid

12 /adenylyl cyclase-dependent, cystic fibrosis transmembrane conductance regulator activity.

13 ffects on the degradation of cystic fibrosis transmembrane conductance regulator and CPY*, which is a

14 he NHERF1-binding domains of cystic fibrosis transmembrane conductance regulator and Csk-binding prot

15 secretion appears to require cystic fibrosis transmembrane conductance regulator and electrogenic Na(

16 porters (ABC), including the cystic fibrosis transmembrane conductance regulator and P-glycoprotein.

17 was completely dependent on cystic fibrosis transmembrane conductance regulator and partially depend

18 al exocytosis of NHE3, CFTR (cystic fibrosis transmembrane conductance regulator), and GLUT5 required

19 -dependent activation of the cystic fibrosis transmembrane conductance regulator anion channel was in

20 codon in mRNAs encoding the cystic fibrosis transmembrane conductance regulator anion channel.

21 Opening and closing of the cystic fibrosis transmembrane conductance regulator are controlled by AT

22 We identify the cystic fibrosis transmembrane conductance regulator as a critical regula

23 es, at least in part through cystic fibrosis transmembrane conductance regulator-associated channels,

24 slows the degradation of the cystic fibrosis transmembrane conductance regulator but does not impede

25 unction mutations in the chloride channel CF transmembrane conductance regulator can elevate the acti

26 in gross mislocalization of cystic fibrosis transmembrane conductance regulator, causing marked redu

27 s to the gating mutations of cystic fibrosis transmembrane conductance regulator (CFTR or ABCC7; i.e.

28 Cystic fibrosis transmembrane conductance regulator (CFTR) (ABCC7), uniq

29 ol of cell proliferation and cystic fibrosis transmembrane conductance regulator (CFTR) -driven fluid

30 coid dexamethasone increases cystic fibrosis transmembrane conductance regulator (CFTR) abundance in

31 linone CFTRact-J027 (4) as a cystic fibrosis transmembrane conductance regulator (CFTR) activator wit

32 ates that ivacaftor improves cystic fibrosis transmembrane conductance regulator (CFTR) activity and

33 The cystic fibrosis transmembrane conductance regulator (CFTR) acts as a cha

34 ons to the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) also cause pa

35 membrane, which include the cystic fibrosis transmembrane conductance regulator (CFTR) and Ca(2+)-ac

36 association between lack of cystic fibrosis transmembrane conductance regulator (CFTR) and ceramide

37 ainst other proteins such as cystic fibrosis transmembrane conductance regulator (CFTR) and dystrophi

38 ulated by apically expressed cystic fibrosis transmembrane conductance regulator (CFTR) and large-con

39 nal HCO3(-) exit mediated by cystic fibrosis transmembrane conductance regulator (CFTR) and solute ca

40 alveolar fluid balance: the cystic fibrosis transmembrane conductance regulator (CFTR) and the amilo

41 l permeability and decreased cystic fibrosis transmembrane conductance regulator (Cftr) and the Na-K-

42 /H(+) antiporter, CLC-5, the cystic fibrosis transmembrane conductance regulator (CFTR) and the sodiu

43 g cassette (ABC) transporter cystic fibrosis transmembrane conductance regulator (CFTR) and two other

44 and secrete Cl- through the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel

45 alanine 508 (F508del) in the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel

46 Loss of cystic fibrosis transmembrane conductance regulator (CFTR) anion channel

47 on special properties of the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel

48 in the gene that encodes the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel

49 ons in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel

50 loride permeation pathway in cystic fibrosis transmembrane conductance regulator (CFTR) as a short na

51 ts in functional expression defect of the CF transmembrane conductance regulator (CFTR) at the apical

52 Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) cause recurri

53 inclusion of the full-length cystic fibrosis transmembrane conductance regulator (CFTR) cDNA together

54 espite the importance of the cystic fibrosis transmembrane conductance regulator (CFTR) channel for e

55 The cystic fibrosis transmembrane conductance regulator (CFTR) channel is ac

56 F) mice with a nonfunctional cystic fibrosis transmembrane conductance regulator (CFTR) channel was r

57 ons in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) channel, whic

58 functionally interacts with cystic fibrosis transmembrane conductance regulator (CFTR) channel.

59 lands are important sites of cystic fibrosis transmembrane conductance regulator (CFTR) chloride (Cl(

60 used by loss of a functional cystic fibrosis transmembrane conductance regulator (CFTR) chloride chan

61 e: functional defects of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride chan

62 eine scanning studies of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride chan

63 y the functional expression defect of the CF transmembrane conductance regulator (CFTR) chloride chan

64 The cystic fibrosis transmembrane conductance regulator (CFTR) chloride chan

65 regulatory (R) domain of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride chan

66 s caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) chloride chan

67 all-molecule blockers of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride chan

68 ystic fibrosis (CF), a lack of functional CF transmembrane conductance regulator (CFTR) chloride chan

69 pus oocytes coexpressing the cystic fibrosis transmembrane conductance regulator (CFTR) chloride chan

70 ppropriate activation of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride chan

71 esults from mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) chloride chan

72 eads to an inhibition of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) channel

73 ability, and function of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) channel

74 Cystic fibrosis transmembrane conductance regulator (CFTR) Cl(-) channel

75 the loss of function of the cystic fibrosis transmembrane conductance regulator (CFTR) combined with

76 We evaluated the effects of cystic fibrosis transmembrane conductance regulator (CFTR) deficiency on

77 Smoking is reported to cause cystic fibrosis transmembrane conductance regulator (CFTR) dysfunction i

78 The cystic fibrosis transmembrane conductance regulator (CFTR) epithelial an

79 um (OE) of mice deficient in cystic fibrosis transmembrane conductance regulator (CFTR) exhibits ion

80 n epithelial cells decreases cystic fibrosis transmembrane conductance regulator (CFTR) expression an

81 Here we show that the cystic fibrosis transmembrane conductance regulator (CFTR) facilitates L

82 main interaction between the cystic fibrosis transmembrane conductance regulator (CFTR) first cytosol

83 as correctors of the F508del-cystic fibrosis transmembrane conductance regulator (CFTR) folding defec

84 e findings are directly caused by loss of CF transmembrane conductance regulator (CFTR) function or s

85 Cystic fibrosis transmembrane conductance regulator (CFTR) functions as

86 Mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene affect C

87 covery that mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene cause cy

88 Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene cause cy

89 hesis that disruption of the cystic fibrosis transmembrane conductance regulator (CFTR) gene directly

90 of-function mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene encoding

91 The F508del mutation in the CF transmembrane conductance regulator (Cftr) gene induces

92 ted since the cloning of the cystic fibrosis transmembrane conductance regulator (CFTR) gene is being

93 The F508del mutation in the cystic fibrosis transmembrane conductance regulator (Cftr) gene is belie

94 kb -35 (DHS-35kb) 5' to the cystic fibrosis transmembrane conductance regulator (CFTR) gene is evide

95 he DeltaF508 mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene is the m

96 ease-causing mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene is the o

97 The most common cystic fibrosis transmembrane conductance regulator (CFTR) gene mutation

98 The cystic fibrosis transmembrane conductance regulator (CFTR) gene provides

99 brosis (CF) is caused by mutations in the CF transmembrane conductance regulator (CFTR) gene that imp

100 It is caused by mutations in the CF transmembrane conductance regulator (CFTR) gene that is

101 V1, expressing a full-length cystic fibrosis transmembrane conductance regulator (CFTR) gene, is capa

102 .7-kb promoter region of the cystic fibrosis transmembrane conductance regulator (CFTR) gene, we defi

103 s caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which e

104 the F508del mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

105 g chromatin structure at the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

106 CF), a disease caused by mutations in the CF transmembrane conductance regulator (CFTR) gene.

107 oss 250 kb, encompassing the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

108 e caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

109 e caused by mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

110 In those with severe CF transmembrane conductance regulator (CFTR) genotypes, IR

111 binding domain (NBD2) of the cystic fibrosis transmembrane conductance regulator (CFTR) has lagged be

112 e than 2000 mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) have been des

113 es (MPhis) with mutations in cystic fibrosis transmembrane conductance regulator (CFTR) have blunted

114 function of Slc26a6 and the cystic fibrosis transmembrane conductance regulator (CFTR) in HeLa cells

115 rosis homozygous for F508del-cystic fibrosis transmembrane conductance regulator (CFTR) in placebo-co

116 is to efficiently and safely express the CF transmembrane conductance regulator (CFTR) in the approp

117 Loss of function of the cystic fibrosis transmembrane conductance regulator (CFTR) in the biliar

118 The role of Pseudomonas aeruginosa and CF transmembrane conductance regulator (CFTR) in Treg regul

119 used by the F508 mutation in cystic fibrosis transmembrane conductance regulator (CFTR) include a "co

120 Cystic fibrosis transmembrane conductance regulator (CFTR) inhibitory fa

121 The virulence factor cystic fibrosis transmembrane conductance regulator (CFTR) inhibitory fa

122 PTEN and the CF transmembrane conductance regulator (CFTR) interacted di

123 Cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP-act

124 Cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP/pro

125 Cystic fibrosis transmembrane conductance regulator (CFTR) is a chloride

126 The Cystic Fibrosis Transmembrane conductance Regulator (CFTR) is a chloride

127 The cystic fibrosis transmembrane conductance regulator (CFTR) is a chloride

128 Cystic fibrosis transmembrane conductance regulator (CFTR) is a Cl(-)-se

129 cAMP-activated Cl(-) channel cystic fibrosis transmembrane conductance regulator (CFTR) is a major pr

130 brates, the chloride channel cystic fibrosis transmembrane conductance regulator (CFTR) is a master r

131 The cystic fibrosis transmembrane conductance regulator (CFTR) is a member o

132 Cystic fibrosis transmembrane conductance regulator (CFTR) is a membrane

133 Cystic fibrosis transmembrane conductance regulator (CFTR) is a multidom

134 The cystic fibrosis transmembrane conductance regulator (CFTR) is a plasma-m

135 The cystic fibrosis transmembrane conductance regulator (CFTR) is a unique i

136 Expression of the cystic fibrosis transmembrane conductance regulator (CFTR) is altered in

137 Cystic fibrosis transmembrane conductance regulator (CFTR) is an anion c

138 The cystic fibrosis transmembrane conductance regulator (CFTR) is an anion c

139 The cystic fibrosis transmembrane conductance regulator (CFTR) is an anion c

140 The cystic fibrosis transmembrane conductance regulator (CFTR) is an anion c

141 The cystic fibrosis transmembrane conductance regulator (CFTR) is an ATP-bin

142 ABSTRACT: Cystic fibrosis transmembrane conductance regulator (CFTR) is an ATP-gat

143 The cystic fibrosis transmembrane conductance regulator (CFTR) is an epithel

144 The cystic fibrosis transmembrane conductance regulator (CFTR) is an epithel

145 an DeltaF508 mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) is associated

146 Endocytic recycling of the cystic fibrosis transmembrane conductance regulator (CFTR) is blocked by

147 The cystic fibrosis transmembrane conductance regulator (CFTR) is expressed

148 modulator compounds for the cystic fibrosis transmembrane conductance regulator (CFTR) is key for th

149 Cystic fibrosis transmembrane conductance regulator (CFTR) is one ERAD s

150 08 deletion (F508del) in the cystic fibrosis transmembrane conductance regulator (CFTR) is the most c

151 Cystic fibrosis transmembrane conductance regulator (CFTR) is the only l

152 Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) is the secret

153 gamma stimulation in vivo in cystic fibrosis transmembrane conductance regulator (Cftr) knockout mice

154 binding domain (NBD1) of the cystic fibrosis transmembrane conductance regulator (CFTR) leads to defe

155 s or dysfunction of the cystic fibrosis (CF) transmembrane conductance regulator (CFTR) leads to impa

156 We hypothesized that cystic fibrosis transmembrane conductance regulator (CFTR) may be critic

157 s (FPOP) for footprinting of cystic fibrosis transmembrane conductance regulator (CFTR) membrane tran

158 mbination treatment with the cystic fibrosis transmembrane conductance regulator (CFTR) modulators te

159 The most prevalent cystic fibrosis transmembrane conductance regulator (CFTR) mutation caus

160 e carrying the most frequent cystic fibrosis transmembrane conductance regulator (CFTR) mutation in h

161 Using 20 variants from cystic fibrosis transmembrane conductance regulator (CFTR) nucleotide-bi

162 Inhibition of either cystic fibrosis transmembrane conductance regulator (CFTR) or Na(+)-K(+)

163 The chloride channel of the cystic fibrosis transmembrane conductance regulator (CFTR) participates

164 anine 508 (DeltaF508) in the cystic fibrosis transmembrane conductance regulator (CFTR) plasma membra

165 fold and increased wild-type cystic fibrosis transmembrane conductance regulator (CFTR) plasma membra

166 Ivacaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator r

167 Ivacaftor, a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator,

168 ed by defective or deficient cystic fibrosis transmembrane conductance regulator (CFTR) protein activ

169 DeltaPhe508 mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) protein impai

170 Cystic fibrosis transmembrane conductance regulator (CFTR) protein is a

171 ng the activity of defective cystic fibrosis transmembrane conductance regulator (CFTR) protein is a

172 and decreased apical cilia, cystic fibrosis transmembrane conductance regulator (CFTR) protein level

173 unction or deficiency of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, an e

174 sing of the DeltaF508 mutant cystic fibrosis transmembrane conductance regulator (CFTR) protein.

175 is (CF) is due to a folding defect in the CF transmembrane conductance regulator (CFTR) protein.

176 by the lack of a functional cystic fibrosis transmembrane conductance regulator (CFTR) protein.

177 In the liver, the cystic fibrosis (CF) transmembrane conductance regulator (CFTR) regulates bil

178 hly PKA-phosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) regulatory re

179 type and variant (DeltaF508) cystic fibrosis transmembrane conductance regulator (CFTR) responsible f

180 Deletion of Phe508 from cystic fibrosis transmembrane conductance regulator (CFTR) results in a

181 binding domain (NBD1) of the cystic fibrosis transmembrane conductance regulator (CFTR) results in de

182 ons in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) that compromi

183 ons in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) that impair i

184 brosis (CF) is caused by mutations in the CF transmembrane conductance regulator (CFTR) that prevent

185 ftor is a potentiator of the cystic fibrosis transmembrane conductance regulator (CFTR) that reduces

186 lamotrigine), as well as the cystic fibrosis transmembrane conductance regulator (CFTR) trafficking c

187 Misfolding of DeltaF508 cystic fibrosis (CF) transmembrane conductance regulator (CFTR) underlies pat

188 amino acids inserted at the cystic fibrosis transmembrane conductance regulator (CFTR) W1282X PTC (a

189 ons of the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) which is an a

190 the apical chloride channel cystic fibrosis transmembrane conductance regulator (CFTR) with 90% of p

191 ons of the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) with a preval

192 nique ATP-gated ion channel (cystic fibrosis transmembrane conductance regulator (CFTR)).

193 functional abnormalities of cystic fibrosis transmembrane conductance regulator (CFTR), a 25% reduct

194 f apoptosis and involves the cystic fibrosis transmembrane conductance regulator (CFTR), a cAMP-regul

195 inylation and degradation of cystic fibrosis transmembrane conductance regulator (CFTR), a chloride c

196 we examined the role of the cystic fibrosis transmembrane conductance regulator (CFTR), a Cl(-) and

197 Malfunction of the cystic fibrosis transmembrane conductance regulator (CFTR), a gated path

198 F508del cystic fibrosis transmembrane conductance regulator (CFTR), a well-studi

199 (CF) results from mutations that disrupt CF transmembrane conductance regulator (CFTR), an anion cha

200 al PDZ domains bind the cystic fibrosis (CF) transmembrane conductance regulator (CFTR), an epithelia

201 ajor anion channels, such as cystic fibrosis transmembrane conductance regulator (CFTR), anoctamin-1(

202 he steady state level of the cystic fibrosis transmembrane conductance regulator (CFTR), but the unde

203 genes such as PRSS1, SPINK1, cystic fibrosis transmembrane conductance regulator (CFTR), chymotrypsin

204 ntify the interactome of the cystic fibrosis transmembrane conductance regulator (CFTR), demonstratin

205 of the common mutant of the cystic fibrosis transmembrane conductance regulator (CFTR), F508del, is

206 cal translation speed of the cystic fibrosis transmembrane conductance regulator (CFTR), leading to d

207 s caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR), of which the

208 illustrate that disrupted function of the CF transmembrane conductance regulator (CFTR), such as that

209 ould target the underlying defects in the CF transmembrane conductance regulator (CFTR), the Cystic F

210 shown previously that macrophages lacking CF transmembrane conductance regulator (CFTR), the gene mut

211 e caused by the DeltaF508 mutation in the CF transmembrane conductance regulator (CFTR), which disrup

212 the epithelial Cl(-) channel cystic fibrosis transmembrane conductance regulator (CFTR), which is def

213 KEY POINTS: The cystic fibrosis transmembrane conductance regulator (CFTR), which is def

214 smembrane channel called the cystic fibrosis transmembrane conductance regulator (CFTR), which regula

215 ts of low serum IGF-1 on the cystic fibrosis transmembrane conductance regulator (CFTR), whose defect

216 Golgi-localized cystic fibrosis transmembrane conductance regulator (CFTR)-associated li

217 assessed by forskolin-induced swelling in CF transmembrane conductance regulator (CFTR)-deficient org

218 % compared with control) and cystic fibrosis transmembrane conductance regulator (CFTR)-dependent and

219 estines that inherently lack cystic fibrosis transmembrane conductance regulator (CFTR)-dependent HCO

220 s, cAMP is known to regulate cystic fibrosis transmembrane conductance regulator (CFTR)-mediated anio

221 partially restored DeltaF508-cystic fibrosis transmembrane conductance regulator (CFTR)-mediated cAMP

222 These drugs activate cystic fibrosis transmembrane conductance regulator (CFTR)-mediated flui

223 s caused by mutations of the cystic fibrosis transmembrane conductance regulator (Cftr).

224 secretin receptor, cilia and cystic fibrosis transmembrane conductance regulator (CFTR).

225 c fibrosis (CF) is caused by mutations in CF transmembrane conductance regulator (CFTR).

226 coding for the anion channel cystic fibrosis transmembrane conductance regulator (CFTR).

227 the epithelial anion channel cystic fibrosis transmembrane conductance regulator (CFTR).

228 f Phe-508 (DeltaF508) in the cystic fibrosis transmembrane conductance regulator (CFTR).

229 ssive disorder affecting the cystic fibrosis transmembrane conductance regulator (CFTR).

230 pression and function of the cystic fibrosis transmembrane conductance regulator (CFTR).

231 lial Cl(-) secretion via the cystic fibrosis transmembrane conductance regulator (CFTR).

232 des for a Cl(-) channel, the cystic fibrosis transmembrane conductance regulator (CFTR).

233 ABC transporters such as the cystic fibrosis transmembrane conductance regulator (CFTR).

234 s and quality control of the cystic fibrosis transmembrane conductance regulator (CFTR).

235 ons for the membrane protein cystic fibrosis transmembrane conductance regulator (CFTR).

236 e transporter (AlgE) and the cystic fibrosis transmembrane conductance regulator (CFTR).

237 gene product DeltaF508 cystic fibrosis (CF) transmembrane conductance regulator (CFTR).

238 se (PKG), and opening of the cystic fibrosis transmembrane conductance regulator (CFTR).

239 ATP-gated anion channel, the cystic fibrosis transmembrane conductance regulator (CFTR).

240 lls expressing the misfolded cystic fibrosis transmembrane conductance regulator (CFTR).

241 ue the trafficking mutant of cystic fibrosis transmembrane conductance regulator (CFTR).

242 e epithelial-cell chloride channel called CF transmembrane conductance regulator (CFTR).

243 e result of mutations in the cystic fibrosis transmembrane conductance regulator (CFTR).

244 The cystic fibrosis transmembrane conductance regulator (CFTR, ABCC7), mutat

245 The cystic fibrosis transmembrane-conductance regulator (CFTR) chloride chan

246 d pancreatic genes (albumin, cystic fibrosis transmembrane conductance regulator [CFTR], and insulin)

247 n amino acid deletion in the cystic fibrosis transmembrane conductance regulator, CFTR.

248 on through activation of the cystic fibrosis transmembrane conductance regulator, CFTR.

249 omal degradation of a mutant cystic fibrosis transmembrane conductance regulator (CFTRDeltaF508) was

250 red an rAAV vector containing a truncated CF transmembrane conductance regulator (CFTRDeltaR) combine

251 re of the outer mouth of the cystic fibrosis transmembrane conductance regulator channel pore: TMs 6

252 denosine 3',5'-monophosphate/cystic fibrosis transmembrane conductance regulator/chloride bicarbonate

253 ary Cl(-) conductance in the cystic fibrosis transmembrane conductance regulator Cl(-) channel requir

254 egments line the pore of the cystic fibrosis transmembrane conductance regulator Cl(-) channel; howev

255 TT, in deletion of Phe508 in cystic fibrosis transmembrane conductance regulator (DeltaF508 CFTR), th

256 These findings link loss of cystic fibrosis transmembrane conductance regulator-dependent alkaliniza

257 tance is mediated by altered cystic fibrosis transmembrane conductance regulator expression and activ

258 of phenylalanine 508 of the cystic fibrosis transmembrane conductance regulator (F508 CFTR) is the m

259 e used mice deficient in the cystic fibrosis transmembrane conductance regulator gene (Cftr) to test

260 ate gene studies include the cystic fibrosis transmembrane conductance regulator gene (CFTR), as well

261 enetic disease caused by mutations in the CF transmembrane conductance regulator gene (CFTR).

262 almost 2,000 variants in the cystic fibrosis transmembrane conductance regulator gene CFTR have empir

263 d to efficiently deliver the cystic fibrosis transmembrane conductance regulator gene to human airway

264 ) cells after treatment with cystic fibrosis transmembrane conductance regulator inhibitor CFTR(inh)-

265 ence factors alkaline protease (AprA) and CF transmembrane conductance regulator inhibitory factor (C

266 eruginosa epoxide hydrolase, cystic fibrosis transmembrane conductance regulator inhibitory factor (C

267 Genetic variation in cystic fibrosis transmembrane conductance regulator is associated with a

268 oncentration of bicarbonate, which mimics CF transmembrane conductance regulator-mediated anion secre

269 veolar macrophages from cystic fibrosis (CF) transmembrane conductance regulator(-/-) mice have impai

270 n of our editase can correct cystic fibrosis transmembrane conductance regulator mRNA, restore full-l

271 As an ion channel, the cystic fibrosis transmembrane conductance regulator must form a continuo

272 ts of the disease-associated cystic fibrosis transmembrane conductance regulator mutant F508del.

273 y the retention of the CFTR (cystic fibrosis transmembrane conductance regulator) mutant protein in t

274 F lung disease in a manner independent of CF transmembrane conductance regulator mutation.

275 ation with and activation of cystic fibrosis transmembrane conductance regulator, one of its binding

276 the threshold, whereas, the cystic fibrosis transmembrane conductance regulator only contributes to

277 zed that transgenic expression of porcine CF transmembrane conductance regulator (pCFTR) cDNA under c

278 Cystic fibrosis transmembrane conductance regulator potentiation by ivac

279 ch was partially reversed by cystic fibrosis transmembrane conductance regulator potentiation with iv

280 e the feasibility of using a cystic fibrosis transmembrane conductance regulator potentiator, ivacaft

281 The Cystic Fibrosis Transmembrane Conductance Regulator protein (CFTR) is a

282 ny missense mutations in the cystic fibrosis transmembrane conductance regulator protein (CFTR) resul

283 he loss of chloride transport through the CF transmembrane conductance regulator protein (CFTR).

284 -length plasmid encoding the cystic fibrosis transmembrane conductance regulator protein was achieved

285 bed in CF including disabled cystic fibrosis transmembrane conductance regulator recruitment to phago

286 The cystic fibrosis transmembrane conductance regulator regulates fluid bala

287 ficient degradation of human cystic fibrosis transmembrane conductance regulator requires function of

288 ) lung disease, the absence of functional CF transmembrane conductance regulator results in Cl(-)/HCO

289 ngiocyte functions including cystic fibrosis transmembrane conductance regulator, secretin receptor,

290 cretion via up-regulation of cystic fibrosis transmembrane conductance regulator, suggesting an impor

291 ngle residue (F508) in CFTR (cystic fibrosis transmembrane conductance regulator) that disrupts the f

292 embrane K(ATP) channels, the cystic fibrosis transmembrane conductance regulator, the transient recep

293 ing functional defect in the cystic fibrosis transmembrane conductance regulator, there is still an u

294 estigation proposes that the cystic fibrosis transmembrane conductance regulator transports extracell

295 romone, Ste6* (sterile), and cystic fibrosis transmembrane conductance regulator, undergo Ubr1-depend

296 Cystic fibrosis transmembrane conductance regulator was internalized in

297 creased levels of functional cystic fibrosis transmembrane conductance regulator were associated with

298 including the anion channel cystic fibrosis transmembrane conductance regulator, which shunt the tra

299 -fibrosis-associated protein cystic fibrosis transmembrane conductance regulator, which upon deletion

300 ease the level of functional cystic fibrosis transmembrane conductance regulator) with the need for m