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1 le of the phospholipase A2 receptor (PLA2R1) transmembrane protein.
2 onal adhesion molecule A (JAM-A), an Ig fold transmembrane protein.
3 es a calcineurin-like metallophosphoesterase transmembrane protein.
4 ating repression of Smoothened, a seven-pass transmembrane protein.
5 preference for acetylating N termini of the transmembrane proteins.
6 membrane (silicalemma) via interactions with transmembrane proteins.
7 city of TMD interactions and the activity of transmembrane proteins.
8 e further research on alloherpesvirus virion transmembrane proteins.
9 tethering, and proper assembly of multi-pass transmembrane proteins.
10 large yet poorly understood family of seven-transmembrane proteins.
11 ical roles in the processing of secreted and transmembrane proteins.
12 e constituent proteins of gap junctions, are transmembrane proteins.
13 matrix proteins, transcription factors, and transmembrane proteins.
14 different, highly polymorphic genes encoding transmembrane proteins.
15 e.g., the ion translocation kinetics of the transmembrane proteins.
16 okines), extracellular matrix molecules, and transmembrane proteins.
17 ncluding cytosolic, membrane-associated, and transmembrane proteins.
18 improving detection of actively secreted and transmembrane proteins.
19 liable topology models for hundreds of human transmembrane proteins.
20 translational N-terminal acetylation of many transmembrane proteins.
21 ess than 2% of all determined structures are transmembrane proteins.
22 SHV-induced expression of interferon induced transmembrane protein 1 (IFITM1) to limit virus infectio
23 n SynDIG4 [also known as Prrt1 (proline-rich transmembrane protein 1)] has recently been identified a
24 eloping FTLD-TDP by increasing expression of Transmembrane Protein 106B (TMEM106B), a lysosomal prote
32 o our knowledge, the first known function of transmembrane protein 178 (Tmem178), a PLCgamma2 downstr
35 i homeostasis, we identified uncharacterized transmembrane protein 199 (TMEM199, previously called C1
36 we determined that fibronectin leucine-rich transmembrane protein 2 (FLRT2), a repulsive ligand of t
37 neuroligin-1 (Nlg1) and leucine-rich-repeat transmembrane protein 2 (LRRTM2) in a dual-colour config
42 ntified mutations in the PRRT2 (proline-rich transmembrane protein 2) gene as the leading cause for a
44 The antiviral restriction factor IFN-induced transmembrane protein 3 (IFITM3) inhibits cell entry of
48 , we show that endogenous interferon-induced transmembrane protein 3 is S-fatty acylated on three cys
51 re, coexpression of the viral reticulon-like transmembrane protein A17 and the capsid-like scaffold p
53 h high resolution structure determination of transmembrane proteins, additional methods, including co
54 GPCR, Gpr175 (also known as Tpra1 or Tpra40: transmembrane protein, adipocyte associated 1 or of 40 k
55 highly induced upon UV treatment, encoding a transmembrane protein and a membrane-bound VirB4/HerA ho
56 nown as the (pro)renin receptor, is a type 1 transmembrane protein and an accessory subunit of the va
57 or activator inhibitor-1 (HAI-1) is a type I transmembrane protein and inhibitor of several serine pr
58 on and identified nectin-4 (PVRL4), a type I transmembrane protein and member of a family of related
59 to blockade by antiviral interferon-induced transmembrane proteins and neutralizing antibody KZ52.
60 tion to PTPRG, CNTNs associate with multiple transmembrane proteins and signal inside the cell via ci
61 fic inside-out signal transfer along cleaved transmembrane proteins and suggest that substrate dimeri
62 e propose that AP-3 and AP-1 directly select transmembrane proteins and target them to axon and dendr
63 eases are involved in ectodomain cleavage of transmembrane proteins, and ADAM17 is known to cleave Ne
64 us and mainly catalyze the Nt-acetylation of transmembrane proteins, and it also harbors lysine N(eps
65 a secreted protein that interacts with ADAM transmembrane proteins, and its mutations are linked to
67 hat mDA progenitors isolated on the basis of transmembrane proteins are capable of extensive, functio
73 t determination of extracellular segments of transmembrane proteins based on the identification of su
74 P2) encodes for CASPR2, a multidomain single transmembrane protein belonging to the neurexin superfam
75 he lipid- and protein-facing residues in the transmembrane protein beta-signal motif depend on the na
78 e presence of IgE autoantibodies against the transmembrane protein BP antigen 2 (BP180, type XVII col
79 R as the Vgamma9Vdelta2 T cell Ag-presenting transmembrane protein butyrophilin 3A1, providing inform
80 ous work from our lab has shown that a small transmembrane protein called sarcospan (SSPN) can enhanc
83 ings demonstrate that the intrinsic shape of transmembrane proteins can determine their cellular loca
85 l-type amino acid transporter 1 (LAT1) is a transmembrane protein carrying bulky and neutral amino a
86 SRC associated with, and phosphorylated, the transmembrane protein CBP/PAG at Tyr-317, resulting in C
87 SIRPalpha ligation by a broadly expressed transmembrane protein, CD47, results in phosphorylation
90 synthase proteins in this large multisubunit transmembrane protein complex and the number of cellulos
91 (CcO) or complex IV (EC 1.9.3.1) is a large transmembrane protein complex that serves as the last en
93 et-endothelial cell adhesion molecule-1 is a transmembrane protein connecting adjacent endothelial ce
94 ese principles, we analyzed 26-residue model transmembrane proteins consisting exclusively of leucine
95 e provide functional evidence showing that a transmembrane protein, Cornichon-1 (CNIH), acts as a car
97 function of STING (TMEM173), an ER-resident transmembrane protein critical for cytoplasmic DNA sensi
99 ivating the SWH pathway independently of the transmembrane protein Crumbs and bypassing the negative
100 olding protein Stardust (Sdt) stabilizes the transmembrane protein Crumbs, a conserved regulator of a
101 way activity is modulated via inter-cellular transmembrane proteins Crumbs and Echinoid that are both
104 sion required the dendrocyte-expressed seven transmembrane protein (DC-STAMP)-dependent non-apoptotic
105 v14/Cornichon family that mediates export of transmembrane proteins despite the potential for such cl
106 in the study of the intracellular traffic of transmembrane proteins due to its tightly regulated traf
107 ntroduced to represent the behavior of cargo transmembrane proteins during the vesicle fusion to the
108 tochondrial uncoupling protein 1, which is a transmembrane protein essentially lacking extramembraneo
109 or expressed on myeloid cells 2 (TREM2) is a transmembrane protein expressed on microglia within the
111 nella-containing vacuole where this putative transmembrane protein facilitates intravacuolar iron acq
112 ein-coupled receptors constitute the largest transmembrane protein family involved in cell signaling.
113 ach, we showed that apoptosis-inducing human transmembrane proteins, FasL and TRAIL, synthesized and
121 hether an internal, in-frame truncation of a transmembrane protein gamma-sarcoglycan is functional.
122 nd genomic approach, we identified the TMEM2 transmembrane protein gene as a direct transcriptional t
123 ree recent studies find that the single-pass transmembrane protein HAP2 mediates gamete fusion and is
127 e-1 (PECAM-1, a highly expressed endothelial transmembrane protein) help to achieve specific therapeu
131 ISGs, the genes encoding interferon-induced transmembrane protein (IFITM) have been reported to inhi
136 cell-intrinsic factors (interferon-inducible transmembrane proteins, IFITMs), on the pH regulation in
137 gs were: (i) the FL strain encodes 16 virion transmembrane proteins; (ii) eight of these proteins are
138 ple leukocyte lineages, and encodes a type I transmembrane protein (IL12Rbeta1) that associates with
139 an enigmatic endoplasmic-reticulum-resident transmembrane protein implicated in a variety of disorde
140 of an apparently immune-invisible borrelial transmembrane protein in facilitating infection and its
141 mice deficient in NRROS, a myeloid-expressed transmembrane protein in the endoplasmic reticulum, deve
144 he tetraspanins are a superfamily of 33 four-transmembrane proteins in mammals, of which the TspanC8
145 we examined coclustering between Gag and the transmembrane proteins in T and HeLa cells using quantit
146 e gained about the structure and function of transmembrane proteins in their native environment.
147 investigated the role of Tmem231, a two-pass transmembrane protein, in MKS complex formation and func
148 -terminal FAT-like domain, some pre-metazoan transmembrane proteins include several YxxP repeats in t
151 cell membrane complexity is the assembly of transmembrane proteins into oligomeric structures, with
154 e that ODZ1 (also known as TENM1), a type II transmembrane protein involved in fetal brain developmen
156 evidence indicates that signaling by the ER transmembrane protein IRE1alpha is critical for this tra
159 /H(+) exchanger type I (chNHE1), a multispan transmembrane protein, is a cellular receptor of the sub
161 steine-rich motor neuron 1 (Crim1), a type I transmembrane protein, is strongly expressed in the deve
162 encodes a previously uncharacterized type I transmembrane protein, KIAA0319L (denoted hereafter as A
164 used to the N terminus of exosome-associated transmembrane protein Lamp2b were cleaved in samples der
165 hybrid SLBs, the role of the PEG-cushion on transmembrane protein lateral mobility was investigated.
168 ur work provides a comprehensive analysis of transmembrane protein localization to the INM and paves
169 antiviral factors IFITMs (interferon-induced transmembrane proteins) located in membrane-bound compar
171 the highly conserved SYTANLAAF motif in the transmembrane protein M3, and the fifth is in an extra-c
175 x is responsible for the cleavage of several transmembrane proteins, most notably the amyloid precurs
177 hologue, and co-expression of Minion and the transmembrane protein Myomaker is sufficient to induce c
178 ed that myomaker, a skeletal muscle-specific transmembrane protein necessary for myoblast fusion, is
179 blished that tyrosine phosphorylation of the transmembrane protein nephrin promotes recruitment of th
181 The normal distribution of nuclear envelope transmembrane proteins (NETs) is disrupted in several hu
182 tions through targeting the nuclear envelope transmembrane proteins (NETs) that direct their normal r
183 affic, including the poorly understood small transmembrane proteins neural-specific gene 1 and 2 (Nsg
185 e-wide haploid genetic screen identified the transmembrane protein neuropilin 2 (NRP2) and tetraspani
188 long-standing puzzle and identifies NACHO, a transmembrane protein of neuronal endoplasmic reticulum
190 data provide genetic evidence that a mutant transmembrane protein of synaptic vesicles in neurons is
193 4) domain of Sun proteins [5-7], a family of transmembrane proteins of the inner nuclear membrane (IN
194 o Alzheimer's disease, but how its action on transmembrane proteins other than the amyloid precursor
195 However, the structural determinants of transmembrane protein partitioning to raft domains are n
197 ch on alloherpesvirus VTPs.IMPORTANCE Virion transmembrane proteins play key roles in the biology of
199 mplex, as CRB1 is a structural and signaling transmembrane protein present in three cell classes: Mul
200 oprotein A repetitions predominant (GARP), a transmembrane protein present on stimulated Tregs but no
202 colocalizes with a group of uropod-directed transmembrane proteins, PSGL-1, CD43, and CD44, at the p
203 ctrochemical methodology for the analysis of transmembrane proteins reconstituted into a liposomal sy
205 ue to mutations in the NPC1 gene, encoding a transmembrane protein related to the Sonic hedgehog (Shh
210 required for transport (ESCRT) to the seven-transmembrane protein Rim21 in the ambient pH signaling
212 cassette-type ATPases, a substrate-specific transmembrane protein (S component) and a transmembrane
215 g prevent the incorporation of the multipass transmembrane proteins serine incorporator 3 (SERINC3) a
217 ched, induces accumulation of the seven-pass transmembrane protein Smoothened (Smo) within the primar
218 SHH signalling is transduced through the transmembrane protein Smoothened (SMO), which localizes
219 r-like receptor Patched1 regulates the seven-transmembrane protein Smoothened remains mysterious, par
220 the ubiquitin hydrolase that deubiquitinates transmembrane proteins sorted as cargoes into ILVs.
221 termini of NPHP4 and NPHP5 interact with the transmembrane protein SSTR3 and thus spatially map to th
222 embrane phase, and have implications for how transmembrane protein structures respond to their physic
225 and is regulated by numerous AMPAR accessory transmembrane proteins such as TARPs, cornichons, and CK
226 s to the distribution within synapses of key transmembrane proteins, such as receptors, can dramatica
228 tion of the atypical AMPA receptor auxiliary transmembrane protein SynDIG1 regulates its stability an
229 ic transmembrane protein (S component) and a transmembrane protein (T component) that physically inte
232 Tregs, TGF-beta1 activation requires GARP, a transmembrane protein that binds and presents latent TGF
233 onventional autophagic activity of TMEM59, a transmembrane protein that contains the WD40 domain-bind
236 vivirus nonstructural protein 2B (NS2B) is a transmembrane protein that functions as a cofactor for v
238 how that NRG3, like CRD-NRG1, is a dual-pass transmembrane protein that harbors a second transmembran
240 nd that tetherin, a broad-spectrum antiviral transmembrane protein that inhibits the egress of a vari
241 ion by tetherin (BST-2 or CD317), which is a transmembrane protein that inhibits virus release from i
242 y to amino acid transporters, as a lysosomal transmembrane protein that interacts with the Rag guanos
243 C-terminal subunit (MUC1-C) is an oncogenic transmembrane protein that is aberrantly expressed in MM
244 ceptor is an evolutionarily highly conserved transmembrane protein that is essential to a wide spectr
246 prostate specific membrane antigen (PSMA), a transmembrane protein that is overexpressed in prostate
247 synthesized as a highly glycosylated type I transmembrane protein that is subsequently cleaved, resu
250 precursor-like protein 1 (APLP1) is a type I transmembrane protein that plays a role in synaptic adhe
251 as TMEM97, an endoplasmic reticulum-resident transmembrane protein that regulates the sterol transpor
253 orobaculum tepidum BchF revealed an integral transmembrane protein that was efficiently isolated by d
255 contact sites composed of clustered connexin transmembrane proteins that act in dual capacities as ch
256 is process is the endocytic retrieval of the transmembrane proteins that are enriched in synaptic ves
257 strictly depends on LAP1 and LULL1, type II transmembrane proteins that are integral parts of the To
261 rface diffusion of GPI-anchored proteins and transmembrane proteins that associate with actin is driv
262 been limited by lack of knowledge regarding transmembrane proteins that can be used to target and is
263 ngs to an evolutionarily conserved family of transmembrane proteins that can interact with a variety
264 ein S-Acyl Transferases (PATs) are multipass transmembrane proteins that catalyze S-acylation (common
265 ture virions, were severely deficient in the transmembrane proteins that comprise the entry fusion co
266 activated, seven-alpha-helical, retinylidene transmembrane proteins that have been identified in thou
268 anins comprise a diverse family of four-pass transmembrane proteins that play critical roles in the i
270 alytical experiments were performed with two transmembrane proteins; the Na(+)/K(+)ATPase that contai
271 gy-related gene 9 (Atg9) encodes a multipass transmembrane protein thought to act as a membrane carri
272 he Bestrophin1 (BEST1) gene, which encodes a transmembrane protein thought to function as an ion chan
276 Palmitoylated cysteines typically target transmembrane proteins to domains enriched in cholestero
277 that are necessary and sufficient to target transmembrane proteins to either the axon or the dendrit
280 isting of vascular endothelial cadherin, the transmembrane protein tyrosine phosphatase LAR, and the
281 ites infecting hepatic cells rely on the PVM transmembrane protein UIS3 to avoid elimination by host-
282 Here, we have reported that the endogenous transmembrane protein upstream-of-mTORC2 (UT2) negativel
283 t of 'core PCP' proteins, which includes the transmembrane proteins Van Gogh-like (Vangl) and Frizzle
285 tes the intracellular trafficking of several transmembrane proteins, we did not detect any effects of
286 riants in MFSD8, a gene encoding a lysosomal transmembrane protein, were identified in 2 families wit
288 tified PbgA, a periplasmic domain-containing transmembrane protein, which binds cardiolipin glyceroph
289 efficient expression and purification of non-transmembrane proteins, which are otherwise refractory t
290 ing 8A (LRRC8A) is an ubiquitously expressed transmembrane protein with 17 leucine-rich repeats (LRRs
292 ar compartment, suggesting that L2 becomes a transmembrane protein with a short luminal portion and w
293 und that OIG-8, a previously uncharacterized transmembrane protein with a single immunoglobulin (Ig)
298 es I and II, which like NRG2 are single-pass transmembrane proteins with an Ig-like domain, share the
299 ACS-array" approach to identify 18 genes for transmembrane proteins with high expression in mDA proge
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