ライフサイエンスコーパス: transmigrate

1 by regulating the numbers of leukocytes that transmigrate.

2 with the endothelium, but the majority still transmigrated.

3 ile 1.6 +/- 0.3% of the progenitor cells had transmigrated.

4 rs with endothelial ICAM-1 as the neutrophil transmigrates.

5 crovascular endothelium before arresting and transmigrating.

6 on leukocyte migration and their ability to transmigrate across an activated endothelial monolayer.

7 ector memory (EM) CD4(+) T cells can rapidly transmigrate across an endothelial cell (EC) monolayer i

8 or cell extravasation where cancer cells can transmigrate across an endothelial monolayer into a hydr

9 Moreover, these nanoplexes were shown to transmigrate across an in vitro model of the blood-brain

10 Human effector memory CD4 T cells may transmigrate across endothelial cell (EC) monolayers eit

11 led that human platelets did not efficiently transmigrate across human epithelial cell monolayers.

12 s of blood-derived monocytes were allowed to transmigrate across human HSECs into a collagen matrix.

13 ributes to the diminished ability of PMNL to transmigrate across model intestinal epithelia.

14 Human neutrophils were induced to transmigrate across monolayers of human lung epithelial

15 proteins ZO-1 and occludin and were able to transmigrate across polarized airway epithelial monolaye

16 is predominantly rounded, and cells reverse transmigrate across sinusoidal endothelium in a largely

17 NS) by HIV-1 infected mononuclear cells that transmigrate across the blood brain barrier (BBB).

18 To infiltrate the CNS, monocytes transmigrate across the selectively permeable blood-brai

19 compromised in their ability to bind to and transmigrate across the squamous epithelium compared to

20 The same cells rapidly (within 15 min) transmigrate across TNF-treated EC monolayers overlaid w

21 at KDR-expressing lymphocytes preferentially transmigrate across TNFalpha-activated ECs.

22 lating human peripheral blood CD4 T cells to transmigrate across tumor necrosis factor (TNF)-treated

23 Monocytes and lymphocytes transmigrated across cytokine-treated cocultures in grea

24 whereas 11.7% +/- 3.3% of proliferating CFCs transmigrated across endothelium, only 1.3% +/- 0.3% of

25 ophages and, to a lesser extent, lymphocytes transmigrated across fetal intestinal epithelia.

26 V-infected macrophages, but not lymphocytes, transmigrated across fetal oral epithelia.

27 rmore, CAR and DeltaCAR Tregs preferentially transmigrated across HLA-A2-expressing endothelial cell

28 Only 40% of firmly adherent monocytes transmigrated across the endothelial monolayer with sign

29 Together, these data show that EBV transmigrates across oral epithelial cells by (i) apical

30 rough narrow capillaries, and actively, when transmigrating across endothelial cells or squeezing thr

31 9 blocked over 80% of human neutrophils from transmigrating across HUVEC monolayers in an in vitro mo

32 f intestinal epithelial cells induces PMN to transmigrate, an in vitro model consisting of cultured h

33 Gal) is co-administered with ET, neutrophils transmigrate and attack parenchymal cells.

34 In these livers, neutrophils did not transmigrate and liver injury was prevented (necrosis: <

35 te, as evidenced by an increased capacity to transmigrate and produce proinflammatory cytokines on st

36 findings were 1) administered MNC hUCB cells transmigrated and diffused into the embryos (E12.5); 2)

37 vant for the injury accumulate in sinusoids, transmigrate, and adhere to hepatocytes.

38 SRF-deficient macrophages fail to spread, transmigrate, and phagocytose bacteria, and SRF-deficien

39 untreated adherent neutrophils rolled, a few transmigrated, and the number that attached decreased wi

40 cells derived from CD16(+) monocytes reverse transmigrated, and their presence was associated with mi

41 A minority of CD16(-) monocytes reverse transmigrated, and these cells stimulated T cell prolife

42 gamma, EGFP(high) cells rolled, adhered, and transmigrated at a rolling velocity slightly higher (11

43 To transmigrate basement membrane, cells must coordinate di

44 rythroid progenitors and pre-B cells neither transmigrate beneath the stroma nor expand-properly in v

45 Transmigrating canine after consultation with the surgeo

46 , which allowed precise visualization of the transmigrating canine as well as ruled out resorption of

47 Transmigrated CD34 cells expressed a higher level of CD3

48 rdingly, the total plating efficiency of the transmigrated CD34+ cells for lineage-committed progenit

49 (LFA)-1 was found, L-selectin expression on transmigrated CD34+ cells was lost, suggesting that shed

50 aternal and embryonic parts of placentas; 4) transmigrated cells corrected Naglu enzyme activity in a

51 d diffused into the embryos (E12.5); 2) some transmigrated cells expressed CD34 and CD117 antigens; 3

52 In particular, the plating efficiency of transmigrated cells for erythroid progenitors was 27-fol

53 r and bone marrow endothelium and that these transmigrated cells preserve their capacity to lyse leuk

54 The number of transmigrated cells was reduced by blocking antibodies t

55 tumor cells was rare, and it seemed that the transmigrated cells were cleared quickly by the lung, le

56 cells expressed CD34 and CD117 antigens; 3) transmigrated cells were found in both the maternal and

57 novel approach for morphological analysis of transmigrating cells, we show that ECs exhibit a polariz

58 In consequence, transmigrated double-knockout macrophages were seen to a

59 o determine the pathway by which neutrophils transmigrated endothelium, we prepared 27 sets of serial

60 the distal portion locally, and thereby the transmigrated epiblast cells emerge as the DVE cells.

61 into PLNs in mice, although LDeltaP T cells transmigrated HEVs more slowly.

62 eased capacity of HIV-infected leukocytes to transmigrate in response to CCL2 correlated with their i

63 ction of leukocytes affects their ability to transmigrate in response to chemokines and to alter BBB

64 at effector memory CD4+ T cells will rapidly transmigrate in response to the inflammatory chemokine I

65 IV-infected cells added to our model did not transmigrate in the absence of CCL2, nor did this condit

66 ed lateral motility on endothelial cells and transmigrate in-efficiently.

67 tory or natural strain T. gondii tachyzoites transmigrated in larger numbers across simulated human r

68 to use very late Ag-4/VCAM-1 interactions to transmigrate into liver parenchyma in vivo.

69 lammation polymorphonuclear leukocytes (PMN) transmigrate into the lumen and release 5'-AMP.

70 In the initial stages of disease, monocytes transmigrate into the subendothelial space and different

71 ukocytes to leave the circulatory system and transmigrate into tissue.

72 itions, when leukocytes need free passage to transmigrate into tissues, TNF-alpha decreases platelet

73 otic tissue, a majority of MP that initially transmigrated into the amnion later exited by migrating

74 that radiolabeled leukocytes from adult rats transmigrated into the peritoneum of other adult rats 5

75 pha, joined by protein kinase C (PKC) alpha, transmigrates into the nucleus.

76 crovascular endothelium before arresting and transmigrating into inflamed tissues.

77 cells would reduce the number of leukocytes transmigrating into the allograft, thereby attenuating t

78 revented hematopoietic progenitor cells from transmigrating into the developing liver, and Gata4-muta

79 ellular migration, LBRC membrane invests the transmigrating leukocyte.

80 This membrane surrounds the transmigrating leukocyte.

81 creased the number of rolling, adhering, and transmigrated leukocytes (P<0.01 vs. control mesenteries

82 creased the number of rolling, adhering, and transmigrated leukocytes.

83 chemokines by pancreatic acinar cells and/or transmigrated leukocytes.

84 pedesis can be mechanically regulated by the transmigrating leukocytes and by proinflammatory signals

85 microvilli-like projections that surrounded transmigrating leukocytes and drove redistribution of th

86 Decoupling the stresses exerted by the transmigrating leukocytes and the VECs reveals that the

87 e to micrometer-scale disruptions induced by transmigrating leukocytes, endothelial cells generate un

88 Light microscopy and ploidy determination of transmigrated MKs demonstrated predominance of polyploid

89 ctin shedding directly regulates polarity in transmigrated monocytes, which affirms an active role fo

90 icantly increased pseudopodial extensions in transmigrating monocytes, which potentiated invasive beh

91 ed from the blood or bone marrow of EAE mice transmigrate more efficiently than do neutrophils of nai

92 Furthermore, brain-derived viruses did not transmigrate more efficiently than lymphoid-derived viru

93 We found that Ly6G(+) cells transmigrated more efficiently across lal(-/-) ECs than

94 ver, once extravasated, CD18(-/-) leukocytes transmigrated more rapidly than their WT counterparts.

95 blockade of histone-DNA complexes attenuated transmigrated neutrophil-induced neuronal death, whereas

96 Transmigrated neutrophils also released decondensed DNA

97 Neurotoxicity was induced by the addition of transmigrated neutrophils or conditioned medium, taken f

98 key neutrophil proteases in the presence of transmigrated neutrophils rescued neuronal viability.

99 Transmigrated neutrophils stained positively for laminin

100 tive alpha6beta1 integrins on the surface of transmigrated neutrophils was blunted in mice deficient

101 Flow cytometric analysis of transmigrated neutrophils with mAb to L-selectin reveale

102 eutrophils or conditioned medium, taken from transmigrated neutrophils, to neurons and was partially

103 AM-1 expression on intravascular and locally transmigrated neutrophils.

104 ells, and we provide evidence for a role for transmigrating neutrophils and other immune cells in the

105 rmore, evidence was obtained indicating that transmigrating neutrophils carry laminins on their cell

106 permissive nature, LERs acted as "gates" for transmigrating neutrophils in all inflammatory reactions

107 In summary, transmigrating neutrophils secrete localized elastase th

108 lization that define the preferred route for transmigrating neutrophils, we have identified a plausib

109 zed transwells, compatible with the study of transmigrating neutrophils.

110 hat are preferentially used and remodeled by transmigrating neutrophils.

111 es attach to endothelial adhesion molecules, transmigrate out of circulation, and localize within tis

112 rane protein occludin in regions of actively transmigrating PMN and in quiescent areas in the biopsy

113 in epithelial cells immediately adjacent to transmigrating PMN.

114 ution of cortactin in the region surrounding transmigrating PMN.

115 In this study, we assessed whether transmigrating PMNs can regulate barrier function throug

116 ences disease outcomes, we hypothesized that transmigrating PMNs influence the transcriptional profil

117 Transmigrating PMNs rapidly depleted microenvironmental

118 issociation, which is also restricted to the transmigrating pseudopod.

119 Moreover, the shedding was localized to transmigrating pseudopods within the subendothelial spac

120 e regulator of shedding) specifically within transmigrating pseudopods.

121 , and T-cell stimulatory capacity of reverse transmigrating (RT) and subendothelial (SE) monocytes we

122 ls through the endothelium and homing of the transmigrated T cells into the pancreatic islets.

123 The total number of adherent plus transmigrated T cells was also similar in both direction

124 fferences in the morphological appearance of transmigrating T cells as well as in the molecules that

125 class II MHC molecules, it is probable that transmigrating T cells encounter cognate antigen on endo

126 By imaging a RhoA activity biosensor in transmigrating T cells, we find that RhoA is locally and

127 nced, regardless of expression of PECAM-1 on transmigrating T cells.

128 More E. chaffeensis-infected monocytes transmigrated than uninfected monocytes, whereas A. phag

129 Notably, blood precursors do not transmigrate the cortex in an undifferentiated state, bu

130 How such an exit is achieved and how cells transmigrate the distinct endothelium of lymphatic vesse

131 bility of melanoma cells to adhere to and to transmigrate through a monolayer of endothelial cells la

132 Studies have shown that MKs may transmigrate through bone marrow endothelial cells (BMEC

133 matrix) and acquire increased proficiency to transmigrate through endothelial barrier (an obligatory

134 Whether leukocytes can transmigrate through endothelial cells, rather than betw

135 ntly interact with endothelial selectins and transmigrate through endothelial monolayers in vitro.

136 ls migrate up a gradient of the drug CNO and transmigrate through endothelial monolayers.

137 sical populations demonstrated an ability to transmigrate through endothelial monolayers.

138 infected macrophages and lymphocytes did not transmigrate through intact adult oral epithelia.

139 ted the ability of pneumococci to invade and transmigrate through monolayers of rat and human brain m

140 rved that these T cells can be recruited and transmigrate through vascular and bone marrow endotheliu

141 Electron microscopy of the cells that transmigrated through the BMEC monolayers in response to

142 n of adherent cells rolled, and the majority transmigrated through the endothelial cell monolayer.

143 y function to maintain neutrophils that have transmigrated through the epithelium in close contact wi

144 olin-1 to the endothelial basal membrane and transmigrated through transcellular passages formed by a

145 ransmission electron microscopy that E. coli transmigrates through BMEC in an enclosed vacuole withou

146 ming firmly adherent on activation, and then transmigrates through the endothelium.

147 However, the relative number of transmigrated to adherent T cells (i.e., the efficiency

148 Cells transmigrating to the H4R agonist, but not H1R, were ske

149 ed us to decipher the detailed morphology of transmigrating tumor cells and associated endothelial ce

150 istribution of LFA-1 on neutrophils actively transmigrating tumor necrosis factor-alpha-activated hum

151 abilized, and the number of neutrophils that transmigrated was increased 10-fold.