ライフサイエンスコーパス: transmissible

1 he discovery a half century ago that CJD was transmissible.

2 lies that this polymorphism is likely highly transmissible.

3 otein aggregates that are characteristically transmissible.

4 k shows that almost half of plasmids are non-transmissible.

5 ice, showing that Abeta strains are serially transmissible.

6 ggesting that it was not neurotoxic, but yet transmissible.

7 of live viral vaccines that are potentially transmissible.

8 here would render a wholly avian H5N1 virus transmissible.

9 ironmental and animal reservoirs, and easily transmissible.

10 r aberrant conformation indefinitely and are transmissible.

11 such as germline or gonosomal mosaicism, is transmissible.

12 smissible by contact, and no longer airborne-transmissible.

13 expressed, functionally active, and germline transmissible.

14 The transmissible agent of prion disease consists of prion p

15 Mammalian prions, transmissible agents causing lethal neurodegenerative di

16 Prions are fatal neurodegenerative transmissible agents causing several incurable illnesses

17 ergence of a potentially virulent and highly transmissible AIV to humans.

18 T has undergone continuous adaptation to its transmissible allograft niche, with overlapping mutation

19 esis, and they suggest that tumorigenesis is transmissible among genetically predisposed individuals.

20 study population, USA300 MRSA appeared more transmissible among household members compared with othe

21 ransmitted by vectors were more likely to be transmissible among humans.

22 ing the 1918 human pandemic virus can become transmissible among mammals by acquiring mutations in he

23 allow a virus possessing subtype H5 HA to be transmissible among mammals.

24 Transmissible amyloid particles called prions are associ

25 d by increased epithelial TLR4 signaling are transmissible and exacerbate dextran sodium sulfate-indu

26 Prion diseases are transmissible and fatal neurodegenerative diseases in wh

27 urces, densely populated areas, and a highly transmissible and lethal viral infection have led to tho

28 Noroviruses are a highly transmissible and major cause of nosocomial gastroenteri

29 eeded polymerization in vitro, only some are transmissible and pathogenic in vivo To probe the struct

30 he viral stocks are functional and mucosally transmissible and the number of variants is conveniently

31 tes formed in the brains of MSA patients are transmissible and, as such, are prions.

32 n LESB58 is highly resistant to antibiotics, transmissible, and associated with increased morbidity a

33 f the human prion diseases, a group of rare, transmissible, and fatal neurologic diseases associated

34 disorders are the prion diseases, which are transmissible, and in which the misfolded proteins ("pri

35 ity is often correctable, may be genetically transmissible, and may be associated with occult health-

36 Notably, this trait was transmissible, and when cohoused with wild-type animals,

37 ed severe human infections and often carries transmissible antibiotic resistance genes.

38 ms of prion propagation, and what makes them transmissible, are poorly understood.

39 serve in multiple facilities that vertically transmissible bacteria in IgA-low mice dominantly lower

40 d been genetically engineered to render them transmissible between ferrets have proved highly controv

41 had created an H5N1 influenza virus that was transmissible between ferrets.

42 engineered the H5N1 virus to make it readily transmissible between ferrets.

43 op microbiota-dependent inflammation that is transmissible between hosts.

44 xperimentally induced influenza infection is transmissible between humans and whether this would form

45 the newly engineered H5N1 strain is probably transmissible between humans as well.

46 t one of these strains will evolve to become transmissible between humans, sparking a major influenza

47 H5N1 control should the virus become readily transmissible between humans.

48 hus several genetic steps away from becoming transmissible between humans.

49 majority of the population becomes airborne-transmissible between humans.

50 ng and immunosuppression, tumours are rarely transmissible between individuals.

51 ened for behaviors that increase the risk of transmissible blood-borne viral (BBV) infection, but the

52 seases such as Creutzfeldt-Jakob disease are transmissible brain proteinopathies, characterized by th

53 mutations in influenza A(H5N1) HA has become transmissible by air among mammals.

54 is B virus (HBV) is one of the major viruses transmissible by blood that causes chronic infection in

55 rpesvirus 8 (HHV-8) is endemic in Uganda and transmissible by blood.

56 bacteriophage or bacteria carrying plasmids transmissible by conjugation.

57 as less pathogenic in mice and ferrets, less transmissible by contact, and no longer airborne-transmi

58 2014 (H5N6), were fully infective and highly transmissible by direct contact in ferrets but showed le

59 have moderate genetic compatibility and are transmissible by direct contact in ferrets.

60 uce ischemic brain injury in mice, an effect transmissible by fecal transplants.

61 ta impact on immunity and stroke outcome was transmissible by microbiota transplantation.

62 Devil facial tumour disease (DFTD) is a transmissible cancer devastating the Tasmanian devil (Sa

63 as an infectious disease, a recently emerged transmissible cancer in Tasmanian devils (Sarcophilus ha

64 an devils have spawned at least two distinct transmissible cancer lineages and suggest that transmiss

65 Devil facial tumor disease (DFTD) is a transmissible cancer that has killed most of the Tasmani

66 It is a transmissible cancer that propagates naturally in dogs.

67 devils (Sarcophilus harrisii) affected by a transmissible cancer, devil facial tumour disease.

68 Here we describe a second transmissible cancer, DFT2, in five devils located in so

69 regulatory mechanisms allows evolvability of transmissible cancers and could affect the evolutionary

70 Clonally transmissible cancers are somatic cell lineages that are

71 ansmissible cancer lineages and suggest that transmissible cancers may arise more frequently in natur

72 ere are only three known naturally occurring transmissible cancers, and these affect dogs, soft-shell

73 es is particularly prone to the emergence of transmissible cancers.

74 Transmissible carbapenem-resistance in Enterobacteriacea

75 bla KPC, encoding a transmissible carbapenemase (KPC), has historically larg

76 , are Gram-negative pathogens that produce a transmissible carbapenemase and are typically resistant

77 ound that NS1 mutants that were not airborne-transmissible caused limited tissue pathology in the upp

78 nimals in the marine environment as a clonal transmissible cell derived from a single original clam.

79 information on key compounds related to non-transmissible chronic diseases (NTCD) in the national fo

80 This transmissible compensatory adaptation relied on environm

81 e epidemic diarrhea virus (PEDV) is a highly transmissible coronavirus that causes a severe enteric d

82 blackbody radiation--the number of reliably transmissible covert bits is at most proportional to the

83 onization and infection with the most common transmissible CPE worldwide, Klebsiella pneumoniae carba

84 Pseudomonas aeruginosa infection liberates transmissible, cytotoxic prion amyloids.

85 pse causing life-threatening and potentially transmissible disease has not been described.

86 ften clear infection, the organism can cause transmissible disease in enough individuals to sustain i

87 ause inclusion body disease (IBD), a serious transmissible disease of snakes.

88 Mya arenaria, are afflicted with an epidemic transmissible disease of the circulatory system closely

89 deal conditions for the emergence of TB as a transmissible disease.

90 thies (TSEs) are fatal neurodegenerative and transmissible diseases caused by prions.

91 The burden of HIV/AIDS and other transmissible diseases is higher in prison and jail sett

92 f most neurodegenerative diseases, including transmissible diseases like prion encephalopathy, inheri

93 istory and remains one of the most important transmissible diseases worldwide.

94 rates to characterize the spread of contact-transmissible diseases.

95 5-methylcytosine abundance in both sexes, a transmissible effect that was maintained in cellular pro

96 The transmissible elements in these five strains represent a

97 The disease has a unique transmissible etiology, and exosomes represent a novel a

98 he three new SHIV(AD8) viruses are mucosally transmissible, exhibited tier 2 sensitivity to anti-HIV-

99 marsupial carnivore, is endangered due to a transmissible facial cancer spread by direct transfer of

100 The Tasmanian devil transmissible facial cancer was first observed in 1996,

101 serendipitously identified that a nongenetic transmissible factor dramatically increased disease susc

102 Prion diseases are a group of transmissible, fatal neurodegenerative disorders associa

103 the induction of flowering downstream of the transmissible FLOWERING LOCUS T (FT) signal.

104 nvestigated in archetype BKPyV, which is the transmissible form of the virus and thought to establish

105 rets, limiting further adaptation to a fully transmissible form.

106 is effect is independent of phagocytosis and transmissible from infected to uninfected mDCs.

107 in which to reduce foraging activity may be transmissible from parent to offspring colony.

108 tics of tall fescue are enhanced by its seed-transmissible fungal symbiont (endophyte) Epichloe coeno

109 that optimize the probability of generating transmissible gametocyte densities without causing illne

110 asmodium falciparum asexual blood stages and transmissible gametocyte forms.

111 Porcine epidemic diarrhea virus (PEDV) and transmissible gastroenteritis virus (TGEV) are economica

112 n, with no cross-reactivity detected against transmissible gastroenteritis virus (TGEV), porcine resp

113 ctures of NV 3CLpro-, poliovirus 3Cpro-, and transmissible gastroenteritis virus 3CLpro- GC376 inhibi

114 tfs4 gene clusters are contained within self-transmissible genomic islands.

115 968 H3 pandemic viruses and with the aerosol-transmissible H5 mutant.

116 As from pandemic viruses and from an aerosol-transmissible H5 mutant.

117 The transmissible H5 reassortant virus preferentially recogn

118 The emergence of human-transmissible H5N1 avian influenza viruses poses a major

119 otential consequences of an engineered human-transmissible H5N1 strain are stunning.

120 Two respiratory-droplet-transmissible H9N1 viruses were selected by this method,

121 s (including lymphatic tuberculosis) are not transmissible, hence representing an evolutionary dead-e

122 Mucosally transmissible, highly replication competent, pathogenic

123 experiments have identified a virus that is transmissible in ferrets, the generally accepted experim

124 fluenza viruses that cause infection and are transmissible in humans involve changes in the receptor

125 olated from diseased pigs are pathogenic and transmissible in pigs, but the reassortant H3N2 virus wi

126 solated in 2009, some of which were airborne-transmissible in the ferret model without prior adaptati

127 bor a complex MDR element residing either on transmissible IncHI1 plasmids or within multiple chromos

128 How they produce a transmissible infection in their arthropod host is just

129 is induction is required to produce a normal transmissible infection.

130 ow that the proportion of vectors developing transmissible infections (sporozoites) was influenced by

131 nnaires alongside tests for HIV and sexually transmissible infections at one of 2 Melbourne, Victoria

132 Here we develop a mathematical model for non-transmissible infections contracted from a localized env

133 The prevalence of transfusion-transmissible infections in the blood supply is higher i

134 Norovirus is a highly transmissible infectious agent that causes epidemic gast

135 ented the first detection of a novel, highly transmissible influenza A virus genotype: six gene segme

136 mal models of influenza, rapidly selects for transmissible influenza A viruses with human receptor (a

137 le to report that ferrets infected by highly transmissible influenza viruses exhale a greater number

138 The transmissible interaction of metabolic and genetic cycle

139 anomolar potency against both pathogenic and transmissible intra-erythrocytic forms of the malaria pa

140 JSRV, the causative agent of a transmissible lung cancer of sheep, is known to be restr

141 short-incubation-period hyper (HY) strain of transmissible mink encephalopathy (TME).

142 milar studies using the HY and DY strains of transmissible mink encephalopathy resulted in minor diff

143 t anaerobic requirements, the infectious and transmissible morphotype is the dormant spore.

144 e found that IsaB expression was elevated in transmissible MRSA.

145 Citrobacter rodentium induces transmissible murine colonic hyperplasia (TMCH) and vari

146 Citrobacter rodentium induces transmissible murine colonic hyperplasia (TMCH) and vari

147 izing the Citrobacter rodentium (CR)-induced transmissible murine colonic hyperplasia (TMCH) model, w

148 g properties of haemagglutinin (HA) from the transmissible mutant indicate a small increase in affini

149 The crystal structure of the transmissible-mutant HA in complex with receptor analogu

150 It reveals that the transmissible-mutant virus has a 200-fold preference for

151 to acquire affinity for human receptors, and transmissible-mutant-selection experiments have identifi

152 ed by zoonotic influenza virus also controls transmissible mutants that emerge during infection.

153 role for exosomes in facilitating the unique transmissible nature of prions.

154 ly, both models created agents that caused a transmissible neurodegenerative disease in WT mice.

155 sing chronic wasting disease (CWD), a fatal, transmissible, neurodegenerative disorder of cervids of

156 esses in the control of infectious diseases, transmissible pathogens still pose an enormous threat to

157 depart from their hosts and become dangerous transmissible pathogens.

158 in the conversion of prion protein (PrP) to transmissible, pathological forms.

159 ich infection, persistence, and induction of transmissible pathology all occur in the lungs.

160 nity, which is crucial for the generation of transmissible pathology.

161 ng a ccd locus can, therefore, function as a transmissible persistence factor.

162 l evolution to investigate how a costly, non-transmissible plasmid, pNUK73, can be maintained in popu

163 la SHV-12 were carried by a 54-kb IncX3 self-transmissible plasmid, which is identical to plasmid pND

164 beta-lactamase enzymes are encoded on highly transmissible plasmids that spread rapidly between bacte

165 that the risk of experiments with mammalian-transmissible, possibly highly virulent influenza viruse

166 The transmissible prion agent is principally formed of PrP(S

167 TSE) in the host does not always result in a transmissible prion disease.

168 different from that of PrP(Sc) could lead to transmissible prion disease.

169 c), induced a pathogenic process that led to transmissible prion disease.

170 Previous studies established that transmissible prion diseases could be induced by in vitr

171 Transmissible prion diseases exhibit a spectrum of disea

172 lic PrP can participate in the generation of transmissible prion-induced toxicity and highlight the u

173 rPSc, a process coupled to the generation of transmissible prions and neurotoxicity.

174 e identification of a misfolded protein with transmissible properties associated with a group of neur

175 a PrP(res) have often been considered as non-transmissible proteinopathies rather than true prion dis

176 tional switches in the in vitro formation of transmissible PrP amyloids.IMPORTANCE Many diseases invo

177 An atypical proteinase K-resistant, transmissible PrP form that resembled the structure of t

178 the structure-pathogenicity relationships of transmissible PrP states.

179 These findings reveal transmissible, rapid, and modifiable effects of diet-by-

180 The most transmissible reassortant genotypes demonstrated in guin

181 ogrammed intestinal microbiota, leading to a transmissible reduced sensitivity to induced colitis.

182 strains of A. baumannii harbor a large, self-transmissible resistance plasmid that carries the negati

183 ing mice by Nodamura virus (NoV), a mosquito-transmissible RNA virus, requires RNAi suppression by it

184 variant can participate in the generation of transmissible scrapie-induced toxicity.

185 cs that are able to target the liver and the transmissible sexual stages are required.

186 ite uses ER stress as a cue to switch to the transmissible sexual stages.

187 strate here that miR156 is a potential graft-transmissible signal that affects plant architecture and

188 both COR and flg22 are required for a graft transmissible signal to recruit FB17 belowground.

189 heterografts suggest that miR156 is a graft-transmissible signal.

190 The development of a panel of mucosally transmissible simian-human immunodeficiency virus (SHIV)

191 The risk of transmission of transmissible spongiform encephalopathies (TSE) between

192 Most current diagnostic tests for transmissible spongiform encephalopathies (TSE) rely on

193 that certain species were not susceptible to transmissible spongiform encephalopathies (TSEs) and the

194 The prions responsible for mammalian transmissible spongiform encephalopathies (TSEs) are due

195 Transmissible spongiform encephalopathies (TSEs) are fat

196 Transmissible spongiform encephalopathies (TSEs) are fat

197 While less studied, pregnancy-related transmissible spongiform encephalopathies (TSEs) have be

198 Transmissible spongiform encephalopathies (TSEs) or prio

199 Human transmissible spongiform encephalopathies (TSEs) or prio

200 isting concerns about the possible spread of transmissible spongiform encephalopathies (TSEs) via blo

201 Classical scrapie is one of the transmissible spongiform encephalopathies (TSEs), a grou

202 Prion diseases, or transmissible spongiform encephalopathies (TSEs), are a

203 Transmissible spongiform encephalopathies (TSEs), includ

204 The agents responsible for transmissible spongiform encephalopathies (TSEs), or pri

205 In transmissible spongiform encephalopathies (TSEs), which

206 e samples from several patients with various transmissible spongiform encephalopathies (variant and s

207 Transmissible spongiform encephalopathies are neurodegen

208 leic acid is required for the infectivity of transmissible spongiform encephalopathies is central to

209 n prion replication and neurotoxicity during transmissible spongiform encephalopathies is undisputed,

210 ) is the most prevalent manifestation of the transmissible spongiform encephalopathies or prion disea

211 Prion diseases (transmissible spongiform encephalopathies) are fatal neu

212 f scrapie, chronic wasting disease and other transmissible spongiform encephalopathies, are misfolded

213 rions, the infectious agents responsible for transmissible spongiform encephalopathies, consist mainl

214 Prions, the etiological agents in transmissible spongiform encephalopathies, exhibit remar

215 d to misfold into the causative agent of the transmissible spongiform encephalopathies, has previousl

216 Originally identified as causative agents of transmissible spongiform encephalopathies, increasing ev

217 The transmissible spongiform encephalopathies, more commonly

218 ion to the role of its abnormal conformer in transmissible spongiform encephalopathies, normal PrP(C)

219 Prions, the agents of transmissible spongiform encephalopathies, require the e

220 es potentially infected with prion diseases (transmissible spongiform encephalopathies, TSE).

221 of fatal neurodegenerative diseases known as transmissible spongiform encephalopathies, which affect

222 rminants that confer this high resistance to transmissible spongiform encephalopathies.

223 otein can form a prion that causes the fatal transmissible spongiform encephalopathies.

224 roup of neurodegenerative disorders known as transmissible spongiform encephalopathies.

225 group of neurodegenerative diseases known as transmissible spongiform encephalopathies.

226 Bovine spongiform encephalopathy (BSE) is a transmissible spongiform encephalopathy (TSE) (or prion

227 This is evidence that transmissible spongiform encephalopathy (TSE) agent prop

228 e pathogenesis of many peripherally acquired transmissible spongiform encephalopathy (TSE) agents is

229 In the study presented here, using the same transmissible spongiform encephalopathy (TSE) animal mod

230 Transmissible spongiform encephalopathy (TSE) can be ind

231 activity and protease-resistant PrP without transmissible spongiform encephalopathy (TSE) clinical s

232 to translocate infectious agents (prions) of transmissible spongiform encephalopathy (TSE) diseases i

233 a novel and advantageous model for studying transmissible spongiform encephalopathy (TSE) infection.

234 Scrapie is the transmissible spongiform encephalopathy (TSE) of sheep a

235 Different transmissible spongiform encephalopathy (TSE)-associated

236 ations require discriminatory testing of all transmissible spongiform encephalopathy (TSE)-positive s

237 wasting disease (CWD) is a universally fatal transmissible spongiform encephalopathy affecting cervid

238 seen in neurodegenerative diseases, such as transmissible spongiform encephalopathy and Alzheimer di

239 Prion diseases or transmissible spongiform encephalopathy diseases are typ

240 Chronic wasting disease (CWD), a transmissible spongiform encephalopathy of cervids, was

241 Chronic wasting disease (CWD), a transmissible spongiform encephalopathy of cervids, was

242 Chronic wasting disease (CWD), a transmissible spongiform encephalopathy of deer, elk, an

243 euroinflammatory response may play a role in transmissible spongiform encephalopathy pathogenesis.

244 Transmissible spongiform encephalopathy-associated forms

245 n healthy organisms and/or at the onset of a transmissible spongiform encephalopathy.

246 has also been shown to develop a spontaneous transmissible spongiform encephalopathy.

247 class of neurodegenerative diseases known as transmissible spongiform encephalopathy.

248 and albendazole) has been shown to clear the transmissible stage of the helminth completely in treate

249 ate vector attraction to hosts infected with transmissible stages of malaria parasites, as well as do

250 Transmissible stages of Toxoplasma gondii store energy i

251 lycosylated PrP(C) (dgPMCAb), an alternative transmissible state referred to as atypical protease-res

252 The genetic diversity of this transmissible strain within infections, revealed by high

253 tic diversity within patients, including for transmissible strains the coexistence of highly divergen

254 16c as targets of convergent evolution among transmissible strains.

255 developmental step occurs: the production of transmissible stumpy forms from proliferative slender fo

256 pts revealed their significant enrichment in transmissible stumpy forms of the parasite.

257 during 2013-14 was 24% (95% CrI 17-30) less transmissible than its oseltamivir-sensitive counterpart

258 as 4% (95% credible interval [CrI] 3-5) more transmissible than its oseltamivir-sensitive predecessor

259 tant (AVR) strains can be intrinsically more transmissible than their contemporaneous antiviral-sensi

260 gic and clinical alterations of T2D might be transmissible through a similar mechanism by which prion

261 re induces changes in chromatin organization transmissible through meiosis and mitosis.

262 uce meiotically stable epialleles, which are transmissible through selection and breeding.

263 n of intra-erythrocytic gametocytes that are transmissible to Anopheles mosquitoes, and human-to-mosq

264 as in diabetic fish, and this impairment was transmissible to daughter cell tissue.

265 type 1 (EBLV-1), a virus causing rabies and transmissible to humans.

266 rimarily because BSE prions were found to be transmissible to humans.

267 eases called spongiform encephalopathies are transmissible to new hosts by agents consisting solely o

268 is is not limited to the lesion site, but is transmissible to normal skin distant from the infection

269 on-target and off-target mutations that are transmissible to offspring.

270 containing multiple resistance determinants transmissible to other bacteria.

271 Scrapie is thus actually transmissible to primates with incubation periods compat

272 e in cytosolic PrP transgenic Drosophila was transmissible to recipient PrP transgenic flies.

273 otype in cytosolic transgenic Drosophila was transmissible to recipient PrP transgenic flies.

274 proportions between donor strains that were transmissible to recipients and that tended to show coin

275 thy (TSE) (or prion disease) that is readily transmissible to sheep by experimental infection and has

276 ia observed in infected Apc (Min/+) mice was transmissible to uninfected mice by intraperitoneal inje

277 estinal production of IL-22 and IgA, and was transmissible to wild-type mice, resulting in increased

278 Transmissible tumors are those that have transcended the

279 Transmissible tumors are uniform in that they have compl

280 In this review, we explore how transmissible tumors in CTVT, DFTD, and as well as the s

281 ella and segmented filamentous bacteria, was transmissible upon fecal transplant, along with the proc

282 Therefore, the radical emergence of more transmissible variants is unlikely, a positive finding,

283 All transmissible variants possessed one of two nonsynonymou

284 Canine transmissible venereal tumor (CTVT) is a parasitic cance

285 Canine transmissible venereal tumor (CTVT) is the oldest known

286 Canine transmissible venereal tumors (CTVT) are likely thousand

287 besity and microbiota-modulating effects are transmissible via horizontal faeces transfer from WEGL-t

288 nly three additional substitutions to become transmissible via respiratory droplets between mammals.

289 human gastrointestinal (GI) tract primarily transmissible via the fecal-oral route; (2) in the moder

290 how much of the variation in SPVL is due to transmissible viral genetics.

291 n of the complex mutational landscape of the transmissible viral genome.

292 The transmissible virus emerged in experimentally infected f

293 sting that mothers were the likely source of transmissible virus to the infant.

294 ompete these strains and become the dominant transmissible virus.

295 nt--could be at increased risk of generating transmissible viruses and initiating chains of human-to-

296 f a pandemic virus in people can happen when transmissible viruses evolve in individuals with zoonoti

297 ate in animals, and can evolve into airborne-transmissible viruses in human beings.

298 bstantially different from that by which non-transmissible wild-type H5 virus HA binds human receptor

299 besity-associated metabolic phenotypes, were transmissible with uncultured fecal communities and with

300 r agents and, to our knowledge, is the first transmissible zebrafish model of a defined human bleedin