ライフサイエンスコーパス: transpeptidase

1 vidual steps catalyzed by a purified E. coli transpeptidase.

2 ly modifies the active-site threonine of the transpeptidase.

3 f the Staphylococcus aureus sortase A (SrtA) transpeptidase.

4 t by the action of the enzyme gamma-glutamyl transpeptidase.

5 which are the substrate of transglycosylase/transpeptidase.

6 phylococcus aureus sortase (SrtA) is a thiol transpeptidase.

7 ates are sequestered in the active site of a transpeptidase.

8 ibers; it contains urease and gamma-glutamyl transpeptidase.

9 cross-linked, and LdtMt2 is the dominant ld-transpeptidase.

10 ibits both a D,D-carboxypeptidase and an L,D-transpeptidase.

11 rminal step in its biosynthesis catalyzed by transpeptidases.

12 ymes, a group of widely distributed cysteine transpeptidases.

13 as conceived as an inhibitor specific for DD-transpeptidases.

14 d designed specifically for inhibition of DD-transpeptidases.

15 es, a recently discovered family of cysteine transpeptidases.

16 m of the cross-linking reaction catalyzed by transpeptidases.

17 y specific D-alanyl-D-alanine(DD)-peptidases/transpeptidases.

18 design of new antibiotic drugs targeting l,d-transpeptidases.

19 gamma-Glutamyl transpeptidase 1 (GGT1) is a cell surface, N-terminal nu

20 first time, we demonstrate that loss of L,D-transpeptidases 1 and 2 of M. tuberculosis (LdtMt1 and L

21 gamma-Glutamyl transpeptidase (28%) and alanine transaminase (ALT) (27%

22 28.6U/L vs 23.8 +/- 14.1U/L), gamma-glutamyl transpeptidase (34.3 +/- 16.6 vs 24.5 +/- 16.8U/L), and

23 higher activity of the enzyme gamma-glutamyl transpeptidase, a membrane-bound enzyme involved in tran

24 % CI, 1.10; 3.18; P = 0.021); gamma-glutamyl transpeptidase above the upper limit of normal (HR, 1.96

25 We demonstrate that this transpeptidase accepts a set of structurally diverse D-a

26 nd to multiple different beta-lactams in the transpeptidase active site and complement these data wit

27 omain--a remarkable 60 A distant from the DD-transpeptidase active site--discovered by crystallograph

28 in separate domains the transglycosylase and transpeptidase activities required for the biosynthesis

29 ptococcus pneumoniae and characterized their transpeptidase activities, using a thioester analog of s

30 ; for example, beta-lactam resistance by L,D-transpeptidase activities.

31 cosyltransferase) and peptide cross-linking (transpeptidase) activities.

32 lkaline phosphatase activity, gamma-glutamyl-transpeptidase activity and physiological responses to s

33 PBP 3 displayed weak transpeptidase activity in a model transpeptidase reacti

34 PBP2 has peptidoglycan transpeptidase activity in the presence of active PBP1A.

35 nd a large periplasmic domain that encodes a transpeptidase activity involved in synthesis of septal

36 ble (the nascent division site) and that the transpeptidase activity of FtsI is not required for asse

37 interpretation of these results is that the transpeptidase activity of FtsI is required, directly or

38 of beta-lactam antibiotics that inhibit the transpeptidase activity of FtsI.

39 how that FtsZ ring constriction requires the transpeptidase activity of FtsI.

40 ocopied by pharmacological inhibition of the transpeptidase activity of GGT in all readouts.

41 rmone by RelA lead to full bypass of the D,D-transpeptidase activity of PBPs and to broad-spectrum be

42 target of beta-lactam antibiotics is the D,D-transpeptidase activity of penicillin-binding proteins (

43 The transpeptidase activity of sortase has been demonstrated

44 We exploit the transpeptidase activity of sortase to install modified p

45 lose proximity of histidine 120, reduces the transpeptidase activity of sortase.

46 susceptible to beta-lactam antibiotics, the transpeptidase activity of their penicillin binding prot

47 dase activity of DacA in addition to the L,D-transpeptidase activity of YcbB.

48 with comparable rates, but exhibited limited transpeptidase activity relative to mammalian gammaGT.

49 B penicillin-binding proteins (PBPs) carry a transpeptidase activity that cross-links peptidoglycan s

50 No transpeptidase activity was apparent in a model transpep

51 gamma-Glutamyl transpeptidase activity was deficient in kidney homogena

52 mpair division but not membrane insertion or transpeptidase activity were found to interfere with loc

53 of Tat on glutathione levels, gamma-glutamyl transpeptidase activity, and the expression and activity

54 activity, acyl-donor substrate specificity, transpeptidase activity, inhibition by a number of activ

55 ically to its cognate PBP and stimulates its transpeptidase activity, thereby facilitating attachment

56 tathione levels and increases gamma-glutamyl transpeptidase activity.

57 one levels and an increase in gamma-glutamyl transpeptidase activity.

58 vides direct genetic evidence that PBP2A has transpeptidase activity.

59 that can be compensated for by PBP2A is the transpeptidase activity.

60 ild-type spores, possibly due to the loss of transpeptidase activity.

61 Sortase A (SrtA) is a bacterial enzyme with transpeptidase activity.

62 to possess as many as five proteins with L,D-transpeptidase activity.

63 acid (BA) levels, and normal gamma-glutamyl transpeptidase activity.

64 riplasmic domain that encodes the catalytic (transpeptidase) activity.

65 s in the urinary excretion of gamma-glutamyl transpeptidase, alkaline phosphatase, lactate dehydrogen

66 Surface gamma-glutamyl transpeptidase, an indirect indicator of redox potential

67 ant PBP1b and PBP5 of Escherichia coli, a dd-transpeptidase and a dd-carboxypeptidase, respectively.

68 s in the urinary excretion of gamma-glutamyl transpeptidase and alkaline phosphatase, and pigments ar

69 Our study suggests that a combination of L,D-transpeptidase and beta-lactamase inhibitors could effec

70 tures, which are positive for gamma-glutamyl transpeptidase and CK-14 and CK-19 and do not express de

71 cholangiocyte-specific genes (gamma-glutamyl transpeptidase and cytokeratin 19) was similar among the

72 Two of the PBP activities include dd-transpeptidase and DD-carboxypeptidase activities, which

73 0 kg/m(2), genotype 2, normal gamma-glutamyl transpeptidase and increased alanine aminotransferase le

74 ntrations of the liver enzyme gamma-glutamyl transpeptidase and lower scores on a measure of alcohol-

75 including PlsX and KASII (FA metabolism), DD-transpeptidase and MurB (peptidoglycan synthesis), glyox

76 inding proteins such as PBP1b that have both transpeptidase and transglycosylase activities.

77 Bacterial transpeptidase and transglycosylase on the surface are e

78 investigated as potential inhibitors of both transpeptidases and beta-lactamases.

79 anations for the existence of monofunctional transpeptidases and glycosidases (glycoside hydrolases),

80 cantly reduced levels of ALP, gamma-glutamyl transpeptidase, and alanine aminotransferase, compared w

81 ed aspartate aminotransferase, gammaglutamyl transpeptidase, and alkaline phosphatase levels were ind

82 al aspartate aminotransferase, gammaglutamyl transpeptidase, and alkaline phosphatase levels.

83 of alanine aminotransferase, gamma-glutamyl transpeptidase, and alkaline phosphatase.

84 hermostable carboxypeptidase, gamma glutamyl-transpeptidase, and deblocking aminopeptidases are absen

85 sage (glutathione peroxidase, gamma-glutamyl transpeptidase, and glutathione S-transferase).

86 alase, glutathione reductase, gamma-glutamyl transpeptidase, and glutathione synthetase in the regene

87 alase, glutathione reductase, gamma-glutamyl transpeptidase, and glutathione synthetase.

88 erases, alkaline phosphatase, gamma glutamyl transpeptidase, and homeostasis model assessment of insu

89 onverted to a dipeptide due to the action of transpeptidase, and the dipeptide is then transported in

90 o simulate how individual transglycosylases, transpeptidases, and endopeptidases could introduce new

91 -linking of the cell wall, carried out by dd-transpeptidases, and the dd-peptidase activity, that rem

92 The L,D-transpeptidase Atu0845 was detected mainly at the growth

93 oglycan is polymerized by monofunctional d,d-transpeptidases belonging to class B penicillin-binding

94 Glyoxalase-I and gamma-glutamyl transpeptidase, both involved in GSH salvage, were found

95 at LdtMt5 is not a functionally redundant ld-transpeptidase, but rather it serves a unique and import

96 sferase pi 7, and for luminal gamma-glutamyl transpeptidase, but they did not express immunoreactive

97 ble pili by a distinct mechanism involving a transpeptidase called sortase.

98 one facilitates occupancy by a second at the transpeptidase catalytic site, thus lowering the minimal

99 It was recently discovered that the same transpeptidases catalyze the metabolic incorporation of

100 cell wall, such that NG PBP3 would act after transpeptidase-catalyzed reactions generate the acylated

101 Sortase, a membrane-anchored transpeptidase, cleaves P2 between the threonine (T) and

102 Sortase, a cysteine-transpeptidase conserved in Gram-positive bacteria, anch

103 icillin-binding protein (PBP), including the transpeptidase conserved motifs SXXK, SXN, and KTG.

104 GGL and gamma-glutamyl transpeptidase constitute a small gene family.

105 Sortase cysteine transpeptidases covalently attach proteins to the bacter

106 Transpeptidases cross-link peptidoglycan oligopeptides t

107 ions of alkaline phosphatase, gamma-glutamyl transpeptidase, cystatin C, neutrophil gelatinase-associ

108 The bacterial D-alanyl-D-alanine transpeptidases (DD-peptidases) are the killing targets

109 rough their inhibition of D-alanyl-D-alanine transpeptidases (DD-peptidases) that catalyze the last s

110 vertheless, the bacterial D-alanyl-D-alanine transpeptidases (DD-peptidases), the killing targets of

111 condary end points, levels of gamma-glutamyl transpeptidase decreased 48%-63%, on average, among subj

112 isease, and 4 others with low gamma-glutamyl transpeptidase disease (levels <100 U/L), were identifie

113 ain relative to that of the carboxy-terminal transpeptidase domain indicate interdomain flexibility.

114 The PBP1b transpeptidase domain is a major target of beta-lactams,

115 in of the native staphylococcal PBP2 and the transpeptidase domain of the PBP2A, a protein imported b

116 h a leucine at amino acid residue 458 of the transpeptidase domain of the protein, close to the SFN c

117 netically spliced into a surface loop of the transpeptidase domain that contains three conserved loop

118 of the transglycosylase domain, but not the transpeptidase domain, of PBP2 of S. aureus prevents exp

119 domain of unknown function, and a catalytic (transpeptidase) domain.

120 Their lethal targets are the transpeptidase domains of penicillin binding proteins (P

121 valently acylate the active sites of the PBP transpeptidase domains.

122 ype serine/threonine kinase and phosphatase, transpeptidase E-transglycosylase Pbp1A are found in FNV

123 ine type D-alanyl-D-alanine carboxypeptidase/transpeptidase (EC ) from Streptomyces sp. strain R61 re

124 ed to be a gamma-glutamylcysteine dipeptidyl transpeptidase (EC 2.3.2.15) and, more recently, as exem

125 d pilus polymers are assembled by a specific transpeptidase enzyme called pilus-specific sortase.

126 cterial peptidoglycan by sortase, a cysteine transpeptidase enzyme.

127 jacent peptide stems are cross-linked by the transpeptidase enzymes of cell wall biosynthesis to prov

128 or the evaluation of three predicted sortase transpeptidase enzymes, which mediate the cell surface p

129 d proteins, and transmembrane gamma-glutamyl transpeptidase exhibited the expected apical localizatio

130 ver histology was normal, but gamma-glutamyl transpeptidase expression was observed, with altered ant

131 The C-terminal domain is a typical transpeptidase fold and contains the three conserved act

132 substrates of sortase A (SrtA), a bacterial transpeptidase, for enzymatic coupling.

133 for the first time an atomic model of an l,d-transpeptidase from Bacillus subtilis bound to its natur

134 litate septal peptidoglycan synthesis by the transpeptidase FtsI (penicillin-binding protein 3).

135 al for subsequent recruitment of its cognate transpeptidase FtsI but not for stabilization of FtsZ ri

136 GSNO), and GSNO activation by gamma-glutamyl transpeptidase (gamma-GT) is required.

137 We found that inhibition of gamma-glutamyl-transpeptidase (gamma-GT) protects human acute promyeloc

138 ucts that could be cleaved by gamma-glutamyl transpeptidase (gamma-GT), found predominantly in renal

139 asis (PFIC) with raised serum gamma-glutamyl transpeptidase (gamma-GT).

140 gamma-Glutamyl transpeptidase (gammaGTase) catalyzes the transfer of th

141 gamma-Glutamyl transpeptidases (gammaGTases) are the only enzymes known

142 persistence determinants, the gamma-glutamyl-transpeptidase GGT and the vacuolating cytotoxin VacA, a

143 i virulence determinants, the gamma-glutamyl transpeptidase GGT and the vacuolating cytotoxin VacA, c

144 The contribution of glutamyl transpeptidase (GGT) (gamma-glutamyltransferase [EC 2.2.

145 bile duct hypoplasia and low gamma glutamyl transpeptidase (gGT) activity.

146 rs of NAFLD, such as elevated gamma glutamyl transpeptidase (GGT) and alanine aminotransferase (ALT)

147 The role of gamma-glutamyl transpeptidase (GGT) and cysteine-S-conjugate beta-lyase

148 e complex by the ectoproteins gamma-glutamyl transpeptidase (GGT) and dipeptidase.

149 Plasma levels of gamma-glutamyl transpeptidase (GGT) are associated with risk factors fo

150 anine transaminase (ALT), and gamma-glutamyl transpeptidase (GGT) as well as histological grade of st

151 ssion of the membrane antigen gamma-glutamyl transpeptidase (GGT) during the promotion and progressio

152 d an additional member of the gamma-glutamyl transpeptidase (GGT) family, gamma-glutamyl leukotrienas

153 ewly identified member of the gamma-glutamyl transpeptidase (GGT) family, we generated null mutations

154 The mouse gamma-glutamyl transpeptidase (GGT) gene encodes seven distinct mRNAs t

155 VacA, lipopolysaccharide, or gamma-glutamyl transpeptidase (GGT) implicated the latter in H. pylori-

156 e of altering the activity of gamma-glutamyl transpeptidase (GGT) in human prostate carcinoma cells.

157 Expression of gamma-glutamyl transpeptidase (GGT) in tumors contributes to resistance

158 gamma-Glutamyl transpeptidase (GGT) is a heterodimeric membrane enzyme

159 gamma-Glutamyl transpeptidase (GGT) is an ectoenzyme that catalyzes the

160 Expression of the ectoenzyme gamma-glutamyl transpeptidase (GGT) is regulated on T lymphocytes.

161 gamma-Glutamyl transpeptidase (GGT) is the enzyme responsible for break

162 gamma-Glutamyl transpeptidase (GGT) is the only enzyme known that can c

163 rtate transaminase (AST), and gamma-glutamyl transpeptidase (GGT) levels (P <.01).

164 Both the presence of gamma-glutamyl transpeptidase (GGT) on the apical brush-border membrane

165 We used mice deficient in gamma-glutamyl transpeptidase (GGT) to analyze the effects of GGT defic

166 The cell surface glycoprotein gamma-glutamyl transpeptidase (GGT) was isolated from healthy human kid

167 evaluation, via staining for gamma-glutamyl transpeptidase (GGT), a marker for dysplastic cell colon

168 lori These include flagellin, gamma-glutamyl transpeptidase (ggt), collagenase, the secreted serine p

169 ssed alpha-fetoprotein (AFP), gamma-glutamyl transpeptidase (GGT), cytokeratin 19 (CK-19), OC.2, and

170 by the sequential reaction of gamma-glutamyl transpeptidase (GGT), gamma-glutamyl cyclotransferase, a

171 ich inhibits GSH breakdown by gamma-glutamyl transpeptidase (GGT), had no effect on the enhanced upta

172 Apical proteins, including gamma-glutamyl transpeptidase (GGT), Na(+)-glucose cotransporter (SGLT1

173 , alkaline phosphatase (ALP), gamma-glutamyl transpeptidase (GGT), or total bilirubin.

174 m of leukotriene C4 (LTC4) in gamma-glutamyl transpeptidase (GGT)-deficient mice and have found subst

175 tin-glutathione complex via a gamma-glutamyl transpeptidase (GGT)-dependent pathway in the proximal t

176 of a gamma-glutamyl group by gamma-glutamyl transpeptidase (GGT).

177 , serial sections stained for gamma-glutamyl-transpeptidase (GGT, a marker of fetal hepatoblasts) and

178 The ectoenzyme, gamma-glutamyl transpeptidase (GGT, EC ) cleaves glutathione (GSH) to f

179 , lactate dehydrogenase [LDH] gamma-glutamyl transpeptidase [GGT]).

180 rtate aminotransferase [AST], gamma-glutamyl transpeptidase [GGT], alkaline phosphatase [ALP], twice

181 mpounds have been identified: gamma-glutamyl transpeptidase (GGT1) and gamma-glutamyl leukotrienase (

182 Blood levels of gamma glutamyl transpeptidase (GGTP), a liver enzyme indicator of alcoh

183 gamma-Glutamyl transpeptidases (GGTs) are essential for hydrolysis of t

184 Sortase A (SrtA), a bacterial transpeptidase, has become widely used for its ability t

185 ntibiotics have been developed to target the transpeptidase; however, the problem of antibiotic resis

186 le under the direction of the gamma-glutamyl transpeptidase-I promoter were developed.

187 spartate aminotransferase, or gamma-glutamyl transpeptidase in donors with HGV infection alone or tho

188 ory increase in the participation of the L,D-transpeptidase in peptidoglycan synthesis.

189 ription of pbpB, the gene encoding the major transpeptidase in S. aureus.

190 t MRSA by inhibiting essential peptidoglycan transpeptidases, including the beta-lactam resistance de

191 antibiotics, which inhibit the bacterial d,d-transpeptidases involved in cell wall biosynthesis, have

192 appear to work in conjunction with dedicated transpeptidases involved in division, elongation, or spo

193 The transpeptidases involved in the synthesis of the bacteri

194 nhibitor of vacuolar gamma-glutamyl cysteine transpeptidase, involved in the breakdown of glutathione

195 isoform of the Staphylococcus aureus sortase transpeptidase is responsible for the covalent attachmen

196 The function of gamma-glutamyl transpeptidase is to cleave glutathione and S-nitrosoglu

197 The cross-linking reaction, catalyzed by transpeptidases, is the last step in cell wall biosynthe

198 These cysteine transpeptidases join proteins bearing an appropriate sor

199 inary protein and creatinine, gamma-glutamyl transpeptidase, lactate dehydrogenase, histologic parame

200 s well tolerated for inactivation of the L,D-transpeptidase LdtMt1 target.

201 blood alcohol concentration, gamma glutamyl transpeptidase level, and short Michigan Alcoholism Scre

202 greater phosphorylation, and gamma-glutamyl transpeptidase levels are reduced compared with those fr

203 mean corpuscular volume, and gamma-glutamyl transpeptidase levels remained significantly different f

204 but all of them had elevated gamma-glutamyl transpeptidase levels.

205 dy mass index, triglycerides, gamma-glutamyl transpeptidase, maximum alanine aminotransferase/asparta

206 Increased activity of gamma-glutamyl transpeptidase may be one mechanism underlying increased

207 osphatase of 75.6%; P<0.0001; gamma-glutamyl transpeptidase of 117.9%, P<0.0001; bilirubin of 50.0%,

208 d localization of the major transglycosylase/transpeptidase of the cell, PBP1.

209 anspeptidase, which in contrast to the other transpeptidases of S. aureus does not experience inhibit

210 -glutamylcysteine synthetase, gamma-glutamyl transpeptidase, or multidrug resistance protein were fou

211 in) and fibrosis (P<.0001 for gamma-glutamyl transpeptidase, P=.01 for alkaline phosphatase, P<.0001

212 richia coli peptidoglycan glycosyltrasferase-transpeptidase PBP1A interacts with the cell elongation-

213 We show that the peptidoglycan transpeptidase Pbp2 also forms a helical pattern that pa

214 interacts with the cell elongation-specific transpeptidase PBP2 in vitro and in the cell.

215 perative functioning of two native S. aureus transpeptidases (PBP2 and PBP4) and an acquired transpep

216 nspeptidases (PBP2 and PBP4) and an acquired transpeptidase (PBP2A) in staphylococcal cell wall biosy

217 tly transcribed pbp4 gene, which encodes the transpeptidase Pbp4.

218 ch specifically inhibits the cell elongation transpeptidase penicillin binding protein 2 in Escherich

219 acteria is mediated by structural changes in transpeptidase penicillin-binding proteins.

220 lated to the altered substrate preference of transpeptidases (penicillin-binding proteins) in the pne

221 While the PBP2 and PBP3 transpeptidases perform highly specialized functions tha

222 animal model for the study of gamma-glutamyl transpeptidase physiology and glutathione metabolism.

223 action of gamma-glutamylcysteine dipeptidyl transpeptidases (phytochelatin synthases; EC 2.3.2.15),

224 f TA1 response to arginine in gamma-glutamyl transpeptidase-positive transformed and tumorigenic cell

225 ug2, and Dug3) but not by the gamma-glutamyl-transpeptidase, raising the question of the role of this

226 ily of low-molecular-weight PBPs that act as transpeptidases rather than hydrolases, but they do not

227 ayed weak transpeptidase activity in a model transpeptidase reaction but was active as an endopeptida

228 nspeptidase activity was apparent in a model transpeptidase reaction.

229 lyze d-alanyl-d-alanine carboxypeptidase and transpeptidase reactions in vivo.

230 (also called PBP3) of Escherichia coli is a transpeptidase required for synthesis of peptidoglycan i

231 (also called PBP3) of Escherichia coli is a transpeptidase required for synthesis of peptidoglycan i

232 known as penicillin-binding protein 3, is a transpeptidase required for the synthesis of peptidoglyc

233 n-binding protein 4 (PBP4) is a nonessential transpeptidase, required for the high levels of peptidog

234 These clusters include the transpeptidase(s) of the sortase family that is/are requ

235 The Staphylococcus aureus transpeptidase Sortase A (SrtA) anchors virulence and co

236 gation that relies on the specificity of the transpeptidase Sortase A (SrtA) for short peptide sequen

237 The Staphylococcus aureus transpeptidase sortase A (SrtA) is responsible for ancho

238 covalently anchored to the cell wall by the transpeptidase Sortase A (SrtA).

239 C-terminal LPXTG motif, whereas the related transpeptidase Sortase B (SrtB) recognizes a C-terminal

240 Here we use the transpeptidase sortase to covalently attach disease-asso

241 ugh a peptide ligation reaction catalyzed by transpeptidase sortase.

242 ll peptidoglycan by catalysis with the thiol transpeptidase sortase.

243 thogens such as Staphylococcus aureus by the transpeptidase sortase.

244 d by linking two non-toxic fragments using a transpeptidase (sortase).

245 The Staphylococcus aureus transpeptidase SrtA catalyzes the covalent attachment of

246 The Staphylococcus aureus sortase transpeptidase SrtA isoform is responsible for the coval

247 izations of staphylococcal SrtA, and related transpeptidases SrtB from S. aureus and Bacillus anthrac

248 t linkage of Cpa to T3 by the sortase family transpeptidase SrtC2 requires the VPPTG motif in the cel

249 ded as an essential cell elongation-specific transpeptidase, switches its localization from a dispers

250 ive bacteria have been shown to attach via a transpeptidase, termed sortase, that cleaves an LPXTG se

251 ignal of protein A as well as sortase A, the transpeptidase that anchors polypeptides to cell wall cr

252 ding protein 3 (PBP3; also called FtsI) is a transpeptidase that catalyzes cross-linking of the pepti

253 ity of the SrtC sortase (BaSrtC), a cysteine transpeptidase that covalently attaches the BasH and Bas

254 Deletion of sortase A, the transpeptidase that covalently couples multiple surface-

255 Here we identify MT2594 as an L,D-transpeptidase that generates 3-->3 linkages in M. tuber

256 -glutamylcysteine (gamma-Glu-Cys) dipeptidyl transpeptidases that catalyze the synthesis of heavy met

257 s into high-molecular-weight PBPs, which are transpeptidases that form peptidoglycan cross-links, and

258 rium tuberculosis is catalyzed by ld- and dd-transpeptidases that generate 3-->3 and 4-->3 transpepti

259 the result of synergistically inhibiting the transpeptidases that introduce 3,3-cross-links while sim

260 These beta-lactams target the transpeptidases that introduce interpeptide cross-links

261 The transpeptidases that perform this cross-linking are impo

262 gamma-Glutamyl transpeptidase, the first enzyme of the gamma-glutamyl c

263 f excess CapD, a B. anthracis gamma-glutamyl transpeptidase, the protective capsule is degraded, and

264 The existence of a second class of transpeptidases, the L,D-transpeptidases, was recently r

265 On acylation of the active sites of dd-transpeptidases, the molecule would organize itself in t

266 function consecutively after gamma-glutamyl transpeptidase to cleave cystinyl-bis-glycine (cys-bis-g

267 eed for GSNO bioactivation by gamma-glutamyl transpeptidase to increase CFTR maturation; 4) surprisin

268 he ability of PBP2a and two native S. aureus transpeptidases to cross-link peptidoglycan strands bear

269 We exploited the promiscuity of bacterial transpeptidases to develop a novel assay for profiling d

270 or sporulation--is to recruit their cognate transpeptidases to the correct subcellular location.

271 say to analyze PG glycosyltransfer (PGT) and transpeptidase (TP) activities of Escherichia coli penic

272 a PG glycosyltransferase (PGT) domain and a transpeptidase (TP) domain.

273 show here that PBP4 preferentially acts as a transpeptidase (TP) in vitro.

274 ial class B penicillin-binding protein PBP2b transpeptidase (TP).

275 contain both glycosyltransferase (GTase) and transpeptidase (TPase) activities, are particularly attr

276 pretreatment body mass index, gamma-glutamyl transpeptidase, triglyceride, IL-28B TT genotype, and se

277 ents were increased levels of gamma-glutamyl transpeptidase (two [4%]), a reduction in the number of

278 Level of gamma-glutamyl transpeptidase was significantly higher in the placebo g

279 f a second class of transpeptidases, the L,D-transpeptidases, was recently reported.

280 cular volume, SGOT, SGPT, and gamma-glutamyl transpeptidase were significantly higher.

281 Unusual 3-->3 cross-links formed by L,D-transpeptidases were first detected in Escherichia coli

282 PBP 2a is a transpeptidase, which in contrast to the other transpept

283 studies of a related enzyme, gamma-glutamyl transpeptidase, which is subject to inhibition by a labi

284 structures were positive for gamma-glutamyl transpeptidase, which suggests that they possess liver-s

285 of antibiotics in human history, inhibit D,D-transpeptidases, which catalyze the final step in peptid

286 Sortase A (SrtA) is a transpeptidase widely used to site-specifically modify p

287 Here we show that production of the L,D-transpeptidase YcbB in combination with elevated synthes