ライフサイエンスコーパス: transport mechanism

1 ormational changes that are critical for the transport mechanism.

2 or investigating the protein's structure and transport mechanism.

3 ynaptic membrane without requiring an active transport mechanism.

4 to employ a diffusion-based, entropy-driven transport mechanism.

5 g an essential function for this loop in the transport mechanism.

6 itical for elucidating the bacterial protein transport mechanism.

7 IA penetrated into the brain by a saturable transport mechanism.

8 of IFN-alpha, but by a facilitated saturable transport mechanism.

9 iffusion was shown to be the only prevailing transport mechanism.

10 central role in the vital nucleocytoplasmic transport mechanism.

11 a framework for understanding the unique Tat transport mechanism.

12 contained calcium, suggesting a storage and transport mechanism.

13 activity appears to act redundantly with the transport mechanism.

14 eby providing further insight in its dynamic transport mechanism.

15 er methylene, consistent with a non-resonant transport mechanism.

16 ecture, suggests the rudiments of a possible transport mechanism.

17 that allows the Na(+) gradient to power the transport mechanism.

18 figures the TMD, two critical aspects of Pgp transport mechanism.

19 MFS and provides new insights into a general transport mechanism.

20 ular orbitals that participate in the charge transport mechanism.

21 urvival/death decisions through a retrograde transport mechanism.

22 with time, providing evidence for an active transport mechanism.

23 ectrochemically doped films to determine the transport mechanism.

24 act actin cytoskeleton, suggesting an active transport mechanism.

25 s in general have adapted around a universal transport mechanism.

26 class IV da neurons but suggests a different transport mechanism.

27 FSD2A harbors unique structural features and transport mechanism.

28 nrecognized rate-limiting barrier in the NSS transport mechanism.

29 ant kinetic and thermodynamic differences in transport mechanisms.

30 ortant for cancer cell regulation of lactate transport mechanisms.

31 stood, much less is known about TIA membrane transport mechanisms.

32 -length MerF provides insights into possible transport mechanisms.

33 linity can give insight into molecular-level transport mechanisms.

34 ne nucleotides [NAD(P)(H)] also regulate ion transport mechanisms.

35 requires sorting signals as well as specific transport mechanisms.

36 al and theoretical analyses of intracellular transport mechanisms.

37 e determination of other biological actinide transport mechanisms.

38 d define a role for CvpA in subverting these transport mechanisms.

39 s, unanswered questions remain regarding the transport mechanisms.

40 ossess distinctive features of catalytic and transport mechanisms.

41 on and make it available to cells via active transport mechanisms.

42 pe fractionation may be influenced by solute-transport mechanisms.

43 phores, presumably owing to the retention of transport mechanisms.

44 Heart mitochondria utilize multiple Ca(2+) transport mechanisms.

45 pment by exploring the nature of oscillatory transport mechanisms.

46 recent advances in the small intestinal ion transport mechanisms.

47 fficients provides new insights into nuclear transport mechanisms.

48 Fe acquisition, Fe storage, and other cation transport mechanisms.

49 en constructed to explore the underlying ion transport mechanisms.

50 en implicate mitochondrial dynamics and axon transport mechanisms.

51 in compliance, and newly characterised water-transport mechanisms.

52 or the early evolution of microbial electron transport mechanisms.

53 Transport mechanisms across such easily p-dopable layers

54 In this study we characterise Hcy transport mechanisms across the microvillous plasma memb

55 These principles of exchange and transport mechanisms across the mitochondrial membrane a

56 the most thorough understanding of the O(2-) transport mechanism along the channels to date, clarifie

57 pair of the CT state undergoes a stretching transport mechanism analogous to an 'inchworm' motion, i

58 es of Peppas equation explains a non Fickian transport mechanism and diffusion or diffusion-swelling

59 ement is blocked with disruption of both the transport mechanism and phosphorylation by PAR-1.

60 provides key information for elucidating the transport mechanism and predicts candidate substrate bin

61 ave been extensively studied with respect to transport mechanism and structure-function relationships

62 The authors examined bicarbonate transport mechanisms and carbonic anhydrase (CA) in porc

63 ncrease the complexity of the intestinal ion transport mechanisms and continue to contribute to a mor

64 highly attractive model systems to study ion-transport mechanisms and could potentially be of high th

65 functions of mRNA levels for a wide range of transport mechanisms and find that in the limit of small

66 t in DNA is important for unravelling charge transport mechanisms and for developing relevant applica

67 Contributions of gas transport mechanisms and fracture complexity to well pro

68 This Review is focused on ion-transport mechanisms and fundamental properties of solid

69 structural components, regulated by nuclear transport mechanisms and host factor binding.

70 rtant for elucidating the fundamental charge transport mechanisms and intrinsic mobility in organic s

71 The major ion transport mechanisms and ion channels that are involved

72 , little is known about claudin partners for transport mechanisms and membrane organization.

73 marily on new insights into osmotic membrane transport mechanisms and on novel membranes and draw sol

74 This study shows that nonvesicular sterol transport mechanisms and STARD4 in particular account fo

75 However, the membrane transport mechanisms and the signaling events involved i

76 , and atmospheric nuclear tests for (129)I), transport mechanisms, and fallout patterns.

77 We identify the microscopic transport mechanisms, and find facile vacancy-assisted m

78 f their chemical transformations, uptake and transport mechanisms, and phytotoxic impacts is still la

79 ng to its long neuron-like hyphae, conserved transport mechanisms, and powerful genetics.

80 i with respect to kinetics, energy coupling, transport mechanisms, and substrate specificity.

81 ial Ca(2+) concentrations, identification of transport mechanisms, and the proximity of mitochondria

82 Alternate maternofetal transport mechanisms appear to provide adequate B12 to t

83 completely understood, insofar as no single transport mechanism appears to account for all of the ob

84 tive contribution and spatial routes of each transport mechanism are largely unknown.

85 Major impediments to understand the transport mechanism are the thousands of FG binding site

86 rve terminals are 5-7 mm, and that vesicular transport mechanisms are not saturated under basal condi

87 Transport mechanisms are not the same for (3)H-thymidine

88 Thus, nuclear transport mechanisms are physiological regulators of bot

89 Therefore, transport mechanisms are required to mediate the movemen

90 and mobilities have not been determined and transport mechanisms are still a matter of guesswork.

91 gradation by PDEs and identify MRP-dependent transport mechanisms as novel regulators of cellular PDE

92 found to be DNA-mediated, utilizing a charge transport mechanism, as the Rh binding sites are spatial

93 sidues will improve the understanding of the transport mechanism, as well as allow comparative studie

94 Here we describe the urea transport mechanism at atomic resolution, revealed by un

95 levels requires the function of distinct ion-transport mechanisms at the cell plasma membrane.

96 TMD-NBD cross-talk is a key step in the transport mechanism because drug binding stimulates ATP

97 a also describe marked redundancy within the transport mechanism, because single-Q-loop mutants are f

98 y represents a fundamental difference in the transport mechanism between ABC exporters and ABC import

99 These observations demonstrate a novel transport mechanism between photoreceptor cells and RPE

100 Oxygen transport mechanisms between gas-surface reactions and s

101 binding domains (NBDs) is fundamental to the transport mechanism, but is poorly understood at the bio

102 nula occludens-1 (PDZ) domains to engage the transport mechanism, but with the PDZ domains deleted, b

103 rate selectivity and the Na(+)-coupled anion transport mechanism by the human SLC13 family and other

104 ct epithelium was developed to determine the transport mechanism by which HCO3(-) ions are secreted a

105 These findings support a novel transport mechanism by which lysophosphatidylcholines ar

106 This finding is a new long-range transport mechanism comparing to the well-established me

107 mT, these observations indicated a saturable transport mechanism consistent with carrier/receptor-med

108 Intramuscular signaling and glucose transport mechanisms contribute to improvements in insul

109 get deeper insight into the underlying mass transport mechanisms controlling drug release from coate

110 esign concepts, electronic structure, charge transport mechanisms, defect states, thin-film processin

111 on to investigate the metabolic pathways and transport mechanisms driving moist acidic tundra CH4 flu

112 a full understanding of the thermal and mass transport mechanisms during DWC processes.

113 his analysis demonstrated that the different transport mechanisms either had a size dependent mobilit

114 The EOF transport mechanism enables highly sensitive detection o

115 This efficient energy transport mechanism enables the allosteric propagation o

116 By means of this delayed ocean transport mechanism, ENSO provides an additional heat su

117 ion of floc from SML biofilms, identifying a transport mechanism entraining SML accumulated microorga

118 However, understanding of the transport mechanism, especially of human ABC exporters,

119 al indicating that alternative ascorbic acid transport mechanisms exist.

120 ed substrate dependences of MjNhaP1, and the transport mechanism explains alkaline down-regulation of

121 ugh lipid membranes, while most known active transport mechanisms facilitate cell uptake of only very

122 techniques has allowed the construction of a transport mechanism for [P(1,2,2,4)][PF(6)].

123 This work describes a unique transport mechanism for a P-type ATPase and provides ins

124 as inhibited, suggesting a retrograde axonal transport mechanism for delivery into the CNS.

125 proton-dependent manner which resembles the transport mechanism for lactate.

126 is, unfortunately, an extremely inefficient transport mechanism for microscale particles.

127 hich Knudsen diffusion would be the dominant transport mechanism for permanent gases.

128 mS/cm to 10 mS/cm, there is a change in mass transport mechanism for protein adsorption, from the shr

129 t contact configurations; (2) the electronic transport mechanism for such molecular junctions is elec

130 e measurements reveal a new singlet-mediated transport mechanism for triplets, which leads to an enha

131 Understanding transport mechanisms for different nucleoside PET tracer

132 for heme biosynthesis have been identified, transport mechanisms for iron, heme, or heme synthesis i

133 ical approach provides novel insights on oil transport mechanisms from deep blowouts and on gauging t

134 Although its transport mechanism has been thoroughly characterized, t

135 However, the molecular transport mechanism has not yet been identified.

136 al NSS protein, LeuT, and thus the principal transport mechanism, has been heavily debated.

137 However, dynamic studies of the transport mechanism have been sparse and indirect.

138 Although most of the transport mechanisms have been discovered at the molecul

139 The feasible transport mechanisms have been generally accounted for o

140 Various hopping and mobility edge transport mechanisms have been proposed, but their exper

141 for other morphogen systems in which complex transport mechanisms have been proposed.

142 sceptor in Saccharomyces cerevisiae Although transport mechanisms have been suggested for other MFS m

143 However, such transport mechanisms have not been defined.

144 The transport mechanisms identified followed a spatial depen

145 ability of actin monomers, suggest an active transport mechanism in both directions.

146 proteoliposomes, the structures explain the transport mechanism in detail.

147 tion, these results support an elevator-type transport mechanism in EIIC.

148 very provides further insights of the charge transport mechanism in perovskite-based optoelectronic d

149 together, our results identified a new iron transport mechanism in plants that could play a major ro

150 Here we provide new insights into the charge-transport mechanism in semiconducting polymers and offer

151 knowledge, a detailed picture of the proton transport mechanism in the central region of ClC-ec1 at

152 ments show that a nucleobase mediated charge transport mechanism in the deep tunneling superexchange

153 ependent conductance showed that the carrier transport mechanism in the GG was thermal excitation, wh

154 characteristics enable a rapid and specific transport mechanism in the physiological context, a noti

155 nergy loss rules out coherent tunneling as a transport mechanism in the thicker films and provides a

156 troscopies supports a core/shell two-channel transport mechanism in this type of solar cells and furt

157 diffusion of bulky molecules via an elegant transport mechanism in which a mobile element formed by

158 cation could be achieved by an elevator-type transport mechanism in which a transport domain binds to

159 e transporter families all share an elevator transport mechanism in which alternating access is provi

160 A proton transport mechanism in which the channel, depending on p

161 Hence transport mechanisms in a cell will influence its respon

162 , as well as having broader implications for transport mechanisms in all ABC proteins.

163 ons provide insights into macroscopic charge transport mechanisms in conjugated polymers and suggest

164 y provides essential insight into the charge transport mechanisms in organic semiconductors.

165 ity of information that exists regarding ion transport mechanisms in prokaryotes.

166 g of the highly regulated membrane and cargo transport mechanisms in relation to polysaccharide depos

167 tes plant development, but the role of auxin transport mechanisms in the context of land plant evolut

168 as been consistently used to examine the ion transport mechanisms in the corneal epithelial cells; ho

169 n diffusion always plays a role on shale gas transport mechanisms in the reconstructed shales.

170 require a detailed knowledge of ferrihydrite transport mechanisms in the subsurface, but such studies

171 ed the relative role of different nucleoside transport mechanisms in uptake and retention of [methyl-

172 ctural elements previously implicated in the transport mechanism, in particular transmembrane helices

173 Examples of transport mechanisms include specific chemotaxis, prefer

174 structure is essential to understanding the transport mechanism including the critical determinants

175 ovide conclusive evidence for the CcO proton transporting mechanism inferred from experiments, while

176 The proposed transport mechanism inherently down-regulates Na(+)/H(+)

177 was found for [(18)F]5, indicating no active transport mechanism into cells.

178 Several bacterial solute transport mechanisms involve members of the periplasmic

179 scanning microscopy, we have identified the transport mechanisms involved in the detrimental focal s

180 The transport mechanism involves co-transport of glutamic ac

181 r lipids, selected tissues evolved dedicated transport mechanisms involving the alpha-tocopherol tran

182 Structural investigations suggest that the transport mechanism is defined by conformational changes

183 than IAA in Arabidopsis hypocotyls, and the transport mechanism is distinct from IAA transport.

184 In the present work, the ion transport mechanism is elucidated by analyzing experimen

185 The charge-transport mechanism is explained by direct experimental

186 other studies, that showed a hopping charge transport mechanism is likely important for PNA duplexes

187 Presently, this bimodal transport mechanism is not well understood and is descri

188 The hCTR1-mediated copper transport mechanism is not well understood, nor has any

189 ed after ACLT, suggesting that a biophysical transport mechanism is responsible for the altered compo

190 asmic transport in eukaryotic cells, but its transport mechanism is still not understood.

191 work relates to function and gives rise to a transport mechanism is still unclear.

192 However, the transport mechanism is still unclear.

193 Central to the transport mechanism is the binding of the uncomplexed me

194 lso show that enhancement of the anterograde transport mechanism is the cause of the seizure phenotyp

195 llular translocation, although its selective transport mechanism is unknown.

196 tructural basis underlying these distinctive transport mechanisms is puzzling because CLC channels an

197 The importance of such intracellular transport mechanisms is underscored by the various disor

198 ent laboratory studies of a newly recognized transport mechanism: "levitation" of saturated sediment

199 We postulate that UapA uses an elevator transport mechanism likely to be shared with other struc

200 nerated in ice-rich subsurface layers with a transport mechanism linked to solar illumination, but th

201 vation suggests that many aspects of the NPC transport mechanism may be understood based on general b

202 re that such a strain-gradient-enhanced mass transport mechanism may prove essential for understandin

203 Similar transport mechanisms may apply to a wide variety of rela

204 s suggests that a so far elusive, more basic transport mechanism must have existed and may still be t

205 ng technology based on the retrograde axonal transport mechanism (neurography), to determine if oxali

206 ptake suggests that pericytes have molecular transport mechanisms not present in other brain cells.

207 However, when d > 4 nm, a change in transport mechanism occurs which coincides with light em

208 The charge transport mechanism of a wire can be revealed by how its

209 The data support a transport mechanism of DRO to groundwater via accidental

210 of SWEETs are valuable for understanding the transport mechanism of eukaryotic SWEETs and may be usef

211 piece of information in modeling the energy transport mechanism of flares, which is an important iss

212 Despite its clinical relevance, the transport mechanism of MATE proteins remains poorly unde

213 The Ca(2+)-regulated surface transport mechanism of MHC class II molecules observed i

214 To understand the transport mechanism of NaCT and INDY proteins, here we r

215 adly used as a model system for studying the transport mechanism of neurotransmitters because of its

216 inomycin, we have elucidated the fundamental transport mechanism of phenylthiosemicarbazones which is

217 protein revealed that the photocycle and the transport mechanism of PsChR1 differ significantly from

218 dings offer a basis for further defining the transport mechanism of sialin and other SLC17 family mem

219 of PaNhaP offer unique new insights into the transport mechanism of sodium/proton antiporters.

220 To investigate the transport mechanism of the complex RbsABC2, we probed in

221 The structure and transport mechanism of the ECF family remain unknown.

222 In this study, the vacuolar transport mechanism of the main TIAs accumulated in C. r

223 The transport mechanism of the two kidney-specific SLC34 pro

224 s for understanding the structure and proton transport mechanism of this protein in brown adipose tis

225 o play a role in the export of zinc, but the transport mechanism of ZntB is poorly understood and bas

226 High-resolution structures and detailed transport mechanisms of APC transporters are currently u

227 ition, physiological relevance, and electron transport mechanisms of bacterial nanowires remain uncle

228 s study places constraints on the source and transport mechanisms of methane found in groundwater wit

229 l allow a more detailed understanding of the transport mechanisms of other plastic crystal electrolyt

230 into the influence of nanostructuring on the transport mechanisms of small molecules and nucleic acid

231 ng of the structural basis for the different transport mechanisms of the SLC1 family.

232 al data that have provided insights into the transport mechanisms of these intricate molecular machin

233 Disruptions of the underlying transport mechanisms, often caused by mutations that alt

234 We then explore the impact of two different transport mechanisms on the vertical concentration distr

235 enging to predict the impacts of various gas transport mechanisms on well performance with arbitrary

236 occus thermophilus, at least two alternative transport mechanisms operate to move peptides into the c

237 We thus report here a unique, activationless transport mechanism, operative over 8-22-nm distances wi

238 d by a relatively low-temperature non-linear transport mechanism or a high-temperature Mott transitio

239 ly associated with particle acceleration and transport mechanisms powered exclusively by enhanced sol

240 l cells is mediated by two distinct membrane transport mechanisms: proton gradient-driven and ATP-bin

241 in the CaCA superfamily are unknown, and the transport mechanism remains speculative.

242 ve been identified, the role of Cl(-) in the transport mechanism remains unclear.

243 Our findings indicate a novel vesicle transport mechanism requiring BLOC-1 and AP-3 complexes

244 The various transport mechanisms responsible for the biokinetics of

245 novel thiazide-sensitive electroneutral NaCl transport mechanism resulting from the parallel operatio

246 conductivity approaching that of metals, the transport mechanism should be discernible by modelling t

247 Different transport mechanisms, spanning from pure Brownian diffus

248 a cytosolic carrier for Ras, the functional transport mechanism still remains largely elusive.

249 ETHODS AND We demonstrate that transcellular transport mechanisms substantially contribute to lymphat

250 wever, other important aspects of the proton transport mechanism such as gating, and the ability to o

251 er it allows for unification of the electron transport mechanisms supporting extracellular mineral re

252 . subtilis encodes yet additional classes of transport mechanisms, suppressor strains that permitted

253 d water molecules in the protomers suggest a transport mechanism that also permits a facultative NO(2

254 These data provide evidence for a transport mechanism that applies to a major class of sec

255 These results confirm an active transport mechanism that can be used to overcome one of

256 n in the AE1(CTD), and to propose a possible transport mechanism that could explain why selected muta

257 ers function according to a non-conventional transport mechanism that defies the fundamental tenets o

258 y a pH gradient across the membrane, using a transport mechanism that does not resemble the one propo

259 ant and previously hidden aspects of the NSS transport mechanism that emphasize the functional import

260 served high KIE values are consistent with a transport mechanism that involves through-H-bonds of the

261 ends represents a newly uncovered chromosome transport mechanism that is independent of plus end forc

262 icle-rich water at the front, highlighting a transport mechanism that is not captured by sediment tra

263 ity, implying an evolutionary conserved heme transport mechanism that predates vertebrate origins.

264 trongly suggest the presence of an active GA transport mechanism that would represent an additional l

265 xperiments were carried out to determine the transport mechanisms that are responsible for the UV (ul

266 ddition to providing insight into the proton transport mechanism, the demonstrated approach offers a

267 azard (5% v/v) if diffusion is the only mass transport mechanism through the deeper vadose zone.

268 that PBLs activated the reverse cholesterol transport mechanism to enhance the metabolism of the oxL

269 question whether trees can rely on a passive transport mechanism to move carbohydrates from their lea

270 es as a carbon source and devotes 30% of all transport mechanisms to carbohydrate import.

271 over long distances, necessitating efficient transport mechanisms to convey target-derived neurotroph

272 Cells employ regulated transport mechanisms to ensure that their plasma membran

273 Retrovirus replication requires specialized transport mechanisms to export genomic mRNA from the nuc

274 Bacteria have evolved several transport mechanisms to maintain metal homeostasis and t

275 ther biomarkers are found to possess evident transport mechanisms to pass the blood-brain barrier.

276 hiphilic copolymers) that exploit endogenous transport mechanisms to traverse the BBB, enabling deliv

277 n sodium, chloride, bicarbonate, and calcium transport mechanisms under physiological and pathophysio

278 omparable to viral trafficking of non-active transport mechanism upon cellular entry, active transpor

279 study aimed to investigate not only the drug transport mechanisms utilised by nifurtimox at the BBB,

280 To explore whether the transport mechanism was altered, the AMT1;1-Q57H mutant

281 The apical to basal transport mechanism was studied using bradykinin as cont

282 Evidence of these transport mechanisms was seen with reduction of insulin

283 bust conclusions about the Na(+)/K(+)-ATPase transport mechanism, we did not rely on ATPase activity

284 at these water wires are central to the H(+) transport mechanism, we identified I109 as the residue t

285 r understanding of the energy deposition and transport mechanisms, we apply a different energy deposi

286 ate how, with new insights into the chemical transport mechanisms, we can move towards a more fundame

287 To evaluate axonal transport mechanisms, we developed a high-resolution ima

288 volume, pseudovacancy arrays, and collective transport mechanisms; we show that the excess volume cor

289 96), Glu(198), Lys(873), and Asn(874) in the transport mechanism were elucidated.

290 served symmetrical residues required for the transport mechanism were found at the water-membrane int

291 nt sensor, but its substrate specificity and transport mechanism were unknown.

292 Three distinct transport mechanisms were observed for 4.5-22-nm-thick o

293 e biosynthetic pathways, whereas siderophore transport mechanisms were retained, suggesting that thes

294 w that AaCAT1 has notable differences in its transport mechanism when compared with related mammalian

295 Cu(+) transfer from chaperones, points to a transport mechanism where backward release of free Cu(+)

296 indings and analyses, we propose a model for transport mechanism where CmeB protomers function indepe

297 ned with functional FRET assays to propose a transport mechanism where each CmeB protomers is functio

298 This transport mechanism, which occurs at applied electric fi

299 The identification of heme and iron transport mechanisms will improve our understanding of b

300 System L constituted the major transport mechanism, with significant BCH inhibition (69