ライフサイエンスコーパス: transport vesicle

1 rface (e.g., transferrin receptor-containing transport vesicles).

2 ient to determine the preferred target for a transport vesicle.

3 ved vesicles such as PTV and pre-chylomicron transport vesicle.

4 til after the viral DNA is released from the transport vesicle.

5 lipid bilayer in an insulin granule or other transport vesicle.

6 ther between endosomes and specialized GLUT4 transport vesicles.

7 ackaging of cargo molecules into the forming transport vesicles.

8 membranes during budding and trafficking of transport vesicles.

9 oteins located at the target membrane and on transport vesicles.

10 the formation of AP-1B-dependent basolateral transport vesicles.

11 fic cargo proteins to be packaged into COPII transport vesicles.

12 irectly retained in the ER and excluded from transport vesicles.

13 ipids move from organelle to organelle using transport vesicles.

14 vesicle fraction (CV2) enriched in ER-Golgi transport vesicles.

15 of endoplasmic reticulum (ER)-derived COPII transport vesicles.

16 ic from the ER to the Golgi via COPII-coated transport vesicles.

17 an external scaffold to form small 50-100-nm transport vesicles.

18 s efficiently packaged into ER-derived COPII transport vesicles.

19 e tip that is almost exclusively occupied by transport vesicles.

20 target by traveling on anterograde-directed transport vesicles.

21 olipid/Vma6p/Vph1p complex into COPII-coated transport vesicles.

22 ing the assembled V0 complex into ER-derived transport vesicles.

23 the COPI coat or efficient recruitment onto transport vesicles.

24 regulating actin polymerization on membrane transport vesicles.

25 palphaf complex was isolated from ER-derived transport vesicles.

26 it may participate in tethering intra-Golgi transport vesicles.

27 rane proteins must be sorted into ER-derived transport vesicles.

28 t the expense of incorporation into lysosome transport vesicles.

29 e transport, via packaging into COPII-coated transport vesicles.

30 veolae from the plasma membrane to form free transport vesicles.

31 l component of endoplasmic reticulum-derived transport vesicles.

32 to regulate the assembly of coat proteins on transport vesicles.

33 ry is coupled to the formation of functional transport vesicles.

34 and are incompatible with packaging into the transport vesicles.

35 membranes as a key step in the formation of transport vesicles.

36 mechanism and regulation of the formation of transport vesicles.

37 C), results in an accumulation of post-Golgi transport vesicles.

38 tory and membrane cargo molecules into COPII transport vesicles.

39 e similar to those described for ER to Golgi transport vesicles.

40 f the endoplasmic reticulum, and some coated transport vesicles.

41 rotein isolated from COPI-coated intra-Golgi transport vesicles.

42 nd remain the most extensively characterized transport vesicles.

43 dding machinery to ensure p24 packaging into transport vesicles.

44 toylation and stable association with axonal transport vesicles.

45 compartments in trans-Golgi network-derived transport vesicles.

46 t proteins exposed on the luminal leaflet of transport vesicles.

47 n the parasite were identified as hemoglobin transport vesicles.

48 n VII, but not collagen I, into COPII-coated transport vesicles.

49 t of the receptors onto the ER-derived COPII transport vesicles.

50 with vacuolar (H(+))-ATPases (V-ATPases) on transport vesicles.

51 ates with an essential component of ER-Golgi transport vesicles.

52 ins are selected and captured into different transport vesicles.

53 elerated biogenesis of the specialized GLUT4 transport vesicles.

54 eNT H(C) sorting but is absent from axonally transported vesicles.

55 is suboptimally located within anterogradely transported vesicles.

56 organelles of the endomembrane system inside transport vesicles, a process mediated by integral membr

57 he Golgi uses GMAP-210 as a filter to select transport vesicles according to their size and bulk lipi

58 First, two types of transport vesicles accumulate at the tER-Golgi interface

59 equestered within a double membrane-enclosed transport vesicle and degraded after vesicle fusion with

60 etween CREBH and the coat protein complex II transport vesicle and thus controls the ER-to-Golgi tran

61 ine motor coordination, we purified neuronal transport vesicles and analyzed their motility via autom

62 granule proteins in the Golgi and associated transport vesicles and displayed reduced secretion of GR

63 sential nutrients by selectively redirecting transport vesicles and hijacking intracellular organelle

64 e protein that functions in generating COPII transport vesicles and in clustering COPII components at

65 s involved in the formation of intracellular transport vesicles and in the selection of cargo for inc

66 a key role in the formation of intracellular transport vesicles and in their movement from one compar

67 ex, also causes retention of perforin in the transport vesicles and inhibits cytotoxicity, indicating

68 heterotypic fusion takes place between small transport vesicles and organelles.

69 eins are transported in different post-Golgi transport vesicles and separately inserted into the plas

70 o map individual nanogold-labelled Fc within transport vesicles and simultaneously to characterize th

71 r sufficient for Sec22p packaging into COPII transport vesicles and subsequent targeting to the Golgi

72 The interaction between v-SNAREs on transport vesicles and t-SNAREs on target membranes is r

73 ls relies on recognition between v-SNAREs on transport vesicles and t-SNAREs on target membranes.

74 hrough a site of action distinct from Nmnat2 transport vesicles and that protein stability, a key det

75 marily occurs before its sorting into axonal transport vesicles and the cleaved fragments segregate i

76 traffic as evidenced by the accumulation of transport vesicles and the decrease in invertase secreti

77 diating the initial physical contact between transport vesicles and their membrane targets.

78 n by mediating the initial tethering between transport vesicles and their membrane targets; the emerg

79 d from the cell surface into clathrin-coated transport vesicles and then recycled to the plasma membr

80 COPII proteins are required to create transport vesicles and to select cargo molecules for tra

81 ndoplasmic reticulum, a Golgi apparatus, and transport vesicles and yet are capable of sorting and de

82 molog that mediates docking of Golgi-derived transport vesicles and, like other members of the syntax

83 ted by integral, membrane proteins from both transport-vesicle and target membranes, called v- and t-

84 to Sec23p and Sec24p, is found on ER-derived transport vesicles, and is required in vitro for the eff

85 te Golgi and trans-Golgi network, associated transport vesicles, and microdomains of dense granule an

86 structures, including lysosomes, endosomes, transport vesicles, and mitochondria.

87 ed for the formation of TGN-derived exocytic transport vesicles, and that the p62(cplx)-associated PI

88 ER-peroxisome transport vesicles appear to rely on a novel budding mec

89 ons of the endoplasmic reticulum where COPII transport vesicles are generated.

90 ites of "transitional ER" (tER), where COPII transport vesicles are produced.

91 Transport vesicles are tethered to their target membrane

92 at small cargoes (which can fit in a typical transport vesicle) are transported by a different mechan

93 at are tuned to detect both the curvature of transport vesicles as well as their bulk lipid content.

94 transits to the vacuole in the Golgi-derived transport vesicles, as defined by mutations in VPS45, an

95 y play an important role during ARF-mediated transport vesicle assembly or release on the Golgi.

96 e ER and to the Golgi, and it is enriched in transport vesicles associated with these organelles.

97 We recently reported that loss of axonal transport vesicle association through mutations in its i

98 pool of clathrin to assemble clathrin-coated transport vesicles at different intracellular locations.

99 This complex(es) is present primarily in transport vesicles at the apical pole of tracheal epithe

100 in cells that are defective in formation of transport vesicles at the ER or in vesicle fusion with t

101 ion that regulates the accumulation of GLUT4 transport vesicles at the plasma membrane.

102 cking of late endosome-derived, Rab9-bearing transport vesicles at the TGN.

103 NARE homolog that participates in docking of transport vesicles at the vacuolar membrane and that the

104 th anterograde and retrograde trafficking of transport vesicles between different endomembrane compar

105 After the onset of mitosis, HPV-harboring transport vesicles bud from the TGN, followed by associa

106 ctive free acids that are required for GLUT4 transport vesicle budding and/or fusion.

107 -kD hydrophilic protein that is required for transport vesicle budding from the ER in Saccharomyces c

108 cytosolic proteins required to reconstitute transport vesicle budding in a cell-free reaction.

109 recruit factor V and factor VIII to sites of transport vesicle budding within the endoplasmic reticul

110 coatomer (COPI) to Golgi membranes to drive transport vesicle budding.

111 e packaging of anterograde cargo into coated transport vesicles budding from the ER [1].

112 vesicles fuse with the cis-side and exit in transport vesicles budding from the trans-side.

113 purifies with KIF1A, recruiting the motor to transport vesicles, but at least one unidentified additi

114 cuole through the secretory pathway in small transport vesicles by a series of vesicle budding and fu

115 te (PtdIns3P), in the formation of secretory transport vesicles by mechanisms conserved in yeast and

116 on the initial recognition of Rab GTPase on transport vesicles by multisubunit tethering complexes a

117 are coordinated with the biogenesis of cargo transport vesicles by phosphatidylinositol 4-kinases (PI

118 precursors are anchored within ER and Golgi transport vesicles by the stromal targeting domain hydro

119 n are packaged inside unique double-membrane transport vesicles called autophagosomes and are targete

120 rises is unclear because kinesin motors that transport vesicles cannot autonomously distinguish dendr

121 Most transmembrane proteins are selected as transport-vesicle cargo through the recognition of short

122 n is involved in the assembly of basolateral transport vesicles carrying vesicular stomatitis virus G

123 rotein 1/2) but were positive for markers of transport vesicles (cation-independent mannose 6-phospha

124 In mammals, transport vesicles coated with coat complex (COP) II del

125 ptors that define a distinct, plant-specific transport vesicle compartment.

126 IV to COPI, endoplasmic reticulum (ER)-Golgi transport vesicles concentrated in the Golgi region in G

127 To directly visualize fusion events of transport vesicles containing the AMPA receptor GluA2 su

128 tly with alpha-SNAP and NSF in the fusion of transport vesicles containing vacuolar cargo proteins wi

129 In mammals, coat complex II (COPII)-coated transport vesicles deliver secretory cargo to vesicular

130 n which the GCC185 tether helps Rab9-bearing transport vesicles deliver their cargo to the trans-Golg

131 ts with brain tumors significantly increased transport vesicle density in tumor capillary endothelial

132 e complex at or before the assembly of an ER transport vesicle dependent on the COPII sorting subunit

133 nternalize macromolecules and particles into transport vesicles derived from the plasma membrane.

134 ork (TGN) is a key site for the formation of transport vesicles destined for different intracellular

135 that can sort both proteins and lipids into transport vesicles destined for either the apical or bas

136 omains and facilitates their collection into transport vesicles destined for the Golgi.

137 efore, KChIP1seems to be targeted to post-ER transport vesicles, different from COPII-coated vesicles

138 min 2-dependent formation of a population of transport vesicles distinct from those generated by A-ty

139 ner, which may facilitate the specificity of transport vesicle docking or targeting to the yeast lyso

140 nd Rab9 act together to drive the process of transport vesicle docking.

141 annose 6-phosphate receptor (MPR)-containing transport vesicles en route to the Golgi.

142 using fluorescent protein markers that label transport vesicles, endosomes, or the actin cytoskeleton

143 propose that ATP release occurs when protein transport vesicles enriched in ATP fuse with the plasma

144 In contrast, photobleaching anterograde transport vesicles entering a bouton inhibits neuropepti

145 Consistent with this proposal, we find that transport vesicles fail to bind to Golgi membranes in vi

146 containing AMPARs are presorted to identical transport vesicles for dendrite delivery, and live imagi

147 rane tubules and their subsequent fission to transport vesicles for sorting of cargo molecules.

148 hosphatase results in a 50-75% inhibition of transport vesicle formation activity in an ER membrane b

149 uggested that Mon1 and Ccz1 functioned after transport vesicle formation but before (or at) the fusio

150 des a mechanism fundamentally different from transport vesicle formation by COPI, likely responsible

151 he coat protein complex II (COPII) catalyzes transport vesicle formation from the endoplasmic reticul

152 ic IgA receptor (pIgA-R)-containing exocytic transport vesicle formation from the TGN.

153 ized and it has been possible to demonstrate transport vesicle formation in vitro.

154 Transport vesicle formation is a key regulatory step of

155 This suggests that subdomain and transport vesicle formation occur as separate sorting st

156 distinct membrane compartments and regulate transport vesicle formation, motility, docking and fusio

157 cruit coat proteins to membranes to initiate transport vesicle formation.

158 ncreased membrane curvature that accompanies transport vesicle formation.

159 ty to bind to MPR cytoplasmic domains during transport vesicle formation.

160 ive mutant supports a direct role of Cvt9 in transport vesicle formation.

161 receptors for cargo exit from the ER and in transport vesicle formation.

162 hat some Rabs may play an additional role in transport vesicle formation.

163 mote membrane bending during endocytosis and transport vesicle formation.

164 orted from the endoplasmic reticulum (ER) in transport vesicles formed by the coat protein complex II

165 selection and membrane deformation to bud a transport vesicle from a donor compartment.

166 initiate the budding of the pre-chylomicron transport vesicle from intestinal endoplasmic reticulum

167 The mechanisms that permit cargo-loaded transport vesicles from different origins to selectively

168 n itinerant ER to Golgi marker protein) into transport vesicles from donor ER membranes.

169 the budding of both COPI and clathrin-coated transport vesicles from Golgi membranes.

170 d analyzed presumptive APP-containing axonal transport vesicles from mouse cortical synaptosomes usin

171 COPII-coated ER-derived transport vesicles from Saccharomyces cerevisiae contain

172 The COPII coat buds transport vesicles from the endoplasmic reticulum that i

173 h a function for dynamin in the formation of transport vesicles from the endothelial cell plasma memb

174 The COPI coat forms transport vesicles from the Golgi complex and plays a po

175 The budding of transport vesicles from the Golgi complex is initiated b

176 domain proteins that function in budding of transport vesicles from the plasma membrane or the Golgi

177 that measures the formation of constitutive transport vesicles from the TGN in a hepatocyte cell-fre

178 Using an assay that studies the release of transport vesicles from the TGN in vitro, we provide fun

179 Kes1p also represses formation of protein transport vesicles from the trans-Golgi network (TGN) th

180 in participates in the formation of distinct transport vesicles from the trans-Golgi network.

181 embrane constituents of ER and Golgi-derived transport vesicles, function in trafficking some secreto

182 tory proteins enter the Golgi apparatus when transport vesicles fuse with the cis-side and exit in tr

183 Rab9-positive transport vesicles fuse with the trans-Golgi network as

184 ntaxin 7 binds alphaSNAP, a key regulator of transport vesicle fusion at multiple stages of the secre

185 in providing the specificity and energy for transport-vesicle fusion and must therefore be correctly

186 eins exit the endoplasmic reticulum (ER) via transport vesicles generated by the essential coat prote

187 arily the same endosomes and exit via shared transport vesicles generated from a retromer-coated endo

188 PS1 variants are inefficiently packaged into transport vesicles generated from the ER.

189 ted on the external surface of anterogradely transported vesicles, have become available, allowing fo

190 prechylomicrons exit the ER in a specialized transport vesicle in the rate-limiting step in the intra

191 and is relevant in the formation of membrane transport vesicles in eukaryotic cells.

192 hodopsin, because they are the most abundant transport vesicles in photoreceptor cells.

193 ecular signatures associated with routing of transport vesicles in photoreceptors are poorly understo

194 h the accumulation of OR-containing putative transport vesicles in the cytosol.

195 The formation of transport vesicles in vitro requires the incubation of a

196 ayed, and the splayed N-terminus can capture transport vesicles in vitro.

197 olgi network that is required for receipt of transport vesicles inbound from late endosomes and for a

198 ll GTPase Ypt1p to facilitate the receipt of transport vesicles inbound from the endoplasmic reticulu

199 tic cells requires that specific v-SNAREs on transport vesicles interact with specific t-SNAREs on ta

200 ting complex and LAMP1 on the surface of the transport vesicles is important for perforin trafficking

201 that Ypt1p, which is present on ER-to-Golgi transport vesicles, is activated at the Golgi once it in

202 red to the plasma membrane via intracellular transport vesicles, it remains localized at the insertio

203 untered Yip1p as a constituent of ER-derived transport vesicles, leading us to hypothesize a direct r

204 here also indicate that the Piccolo-Bassoon transport vesicles leaving the Golgi may undergo further

205 nt protein was expressed in an intracellular transport vesicle-like distribution in transfected Madin

206 OSTA-1 is associated with transport vesicles, localizes to a ciliary compartment s

207 phosphorylated TrkA receptors in retrograde transport vesicles located in the neurites and cell bodi

208 cluded all of the Usher proteins and rab5, a transport vesicle marker.

209 s is that the intracellular destination of a transport vesicle may be determined in part by its coat

210 These results suggest that the MTT formazan-transporting vesicles may be involved in cellular choles

211 FA, the GTP-dependent synthesis of secretory transport vesicles, may be involved in viral RNA replica

212 (20 degrees C) suggests that Asbt follows a transport vesicle-mediated apical sorting pathway that i

213 In eukaryotes, spherical transport vesicles move proteins and lipids from one int

214 Transport vesicles must dock with the appropriate accept

215 ne whose mutations cause the accumulation of transport vesicles near the tips of defective root hairs

216 d its subsequent binding to the sequestering transport vesicles of the autophagy and cytoplasm to vac

217 ins and that it colocalized with proteins in transport vesicles of the biosynthetic and endocytic pat

218 his complex may be responsible for tethering transport vesicles on target membranes.

219 ator of docking and/or fusion of TGN-derived transport vesicles onto the endosome.

220 , resulting in very few enveloped virions in transport vesicles or extracellular space.

221 yte is the generation of the pre-chylomicron transport vesicle (PCTV) from the endoplasmic reticulum

222 testinal ER and generate the pre-chylomicron transport vesicle (PCTV).

223 the endoplasmic reticulum in prechylomicron transport vesicles (PCTV) that transport chylomicrons to

224 ereas another may belong to an anterogradely transported vesicle pool.

225 After incorporation into COPII transport vesicles, protein sorting receptors release bo

226 crucial synaptic components, Piccolo-bassoon Transport Vesicles (PTVs), Synaptic Vesicle Precursors (

227 Similar to protein transport vesicles (PTVs), VTVs require coat complex II

228 onstrated role of t-SNAREs such as Pep12p in transport vesicle recognition, our results indicate that

229 spectrometry, proteomic characterization of transport vesicles remains challenging.

230 n neuronal transport, yet the nature of axon transport vesicles remains enigmatic.

231 The end of the life of a transport vesicle requires a complex series of tethering

232 Fusion of intracellular transport vesicles requires soluble N-ethylmaleimide-sen

233 Formation of ER-derived protein transport vesicles requires three cytosolic components,

234 n VI molecules can coordinate to efficiently transport vesicle-size cargo over 10 microm of the dense

235 me-lapse imaging of synaptic vesicle protein transport vesicles (STVs) indicates that STVs pause repe

236 migrate as cargo on synaptic vesicle protein transport vesicles (STVs).

237 taining vacuole (LCV) with that of secretory transport vesicles surrounding the LCV.

238 ed either for Golgi structure maintenance or transport vesicle tethering, demonstrating the independe

239 off the membrane surface encasing a nascent transport vesicle that is quickly uncoated.

240 cells depleted of GCC185 accumulate MPRs in transport vesicles that are AP-1 decorated.

241 s, these epitopes were localized to distinct transport vesicles that associated with different sets o

242 in transit between organelles is mediated by transport vesicles that bear integral membrane proteins

243 ex (COPII) that captures cargo proteins into transport vesicles that bud from the ER.

244 ns-Golgi network, where they are sorted into transport vesicles that bud off and fuse into condensing

245 ation of endoplasmic reticulum- (ER) derived transport vesicles that carry secretory proteins to the

246 nes, and insulin stimulates the formation of transport vesicles that deliver Glut4 to the cell surfac

247 Transport vesicles that deliver proteins to the cell sur

248 rafficking from the endocytic compartment to transport vesicles that deliver the vitamin to the site

249 0 in the sorting of GLUT4 to the specialized transport vesicles that ferry GLUT4 to the plasma membra

250 affic, proteins are captured into ER-derived transport vesicles that form through the action of the C

251 d with the cytosolic surface of proacrosomic transport vesicles that fuse to create a single large ac

252 Secretory proteins exit the ER in transport vesicles that fuse to form vesicular tubular c

253 pha-interacting protein associated with COPI transport vesicles that may play a role in Galpha-mediat

254 functional characterization of Golgi-derived transport vesicles that were isolated from tissue cultur

255 eticulum and Golgi apparatus, using discrete transport vesicles to exchange their contents, gained im

256 usion of endoplasmic reticulum-derived COPII transport vesicles to form larger cargo containers chara

257 usion of endoplasmic reticulum-derived COPII transport vesicles to form larger cargo containers.

258 ns that later undergo vesiculation, allowing transport vesicles to move along microtubules and return

259 omplex involved in the docking of post-Golgi transport vesicles to sites of membrane remodeling durin

260 in all eukaryotes involved in the fusion of transport vesicles to target membranes.

261 it has been implicated in the trafficking of transport vesicles to the apical plasma membrane of pola

262 yst, a protein complex involved in tethering transport vesicles to the plasma membrane, provides an a

263 ion of recycling endosome-derived retrograde transport vesicles to the TGN.

264 ears to regulate the targeting of retrograde transport vesicles to the TGN.

265 for tethering and fusion of endosome-derived transport vesicles to the trans-Golgi network.

266 et al., acts as a Ypt7 effector that tethers transport vesicles to the vacuole.

267 trafficking in eukaryotic cells by tethering transport vesicles to their destination membranes.

268 ificity of membrane fusion events by linking transport vesicles to their target membrane in an initia

269 chaperonins mediates BBSome assembly, which transports vesicles to the cilia.

270 ex role in the control of granule secretion, transport vesicle trafficking, phagocytosis, and endocyt

271 Defects in retrograde axonal transport, vesicle trafficking and xenobiotic metabolism

272 ost intriguingly, the viral DNA resides in a transport vesicle until mitosis is completed and the nuc

273 art by SNAREs, integral membrane proteins on transport vesicles (v-SNAREs) and target organelles (t-S

274 sis suggests that GMAP-210 tethers authentic transport vesicles via the same mechanism whereby the AL

275 two distinct steps, import into intermediate transport vesicles (Vid vesicles) and Vid vesicle traffi

276 y a specialized ER-derived vesicle, the VLDL transport vesicle (VTV).

277 n a specialized ER-derived vesicle, the VLDL transport vesicle (VTV).

278 A novel "prechylomicron transport vesicle" was identified; its movement to the G

279 ndoplasmic reticulum (ER) to Golgi apparatus transport vesicles, we have created a strain of S. cerev

280 proteins use distinct sets of Golgi-derived transport vesicles, while RIM1alpha associates with vesi

281 NSF attachment protein receptor (v-SNARE) on transport vesicles with a SNARE on the target membrane (

282 ficking depends on the docking and fusion of transport vesicles with cellular membranes.

283 a family of ubiquitous membrane proteins of transport vesicles with no known function.

284 n to play an important role in the fusion of transport vesicles with specific organelles.

285 To fuse transport vesicles with target membranes, proteins of th

286 ering factors mediate initial interaction of transport vesicles with target membranes.

287 interaction and the fusion, respectively, of transport vesicles with target membranes.

288 ganelles that are required for the fusion of transport vesicles with that organelle.

289 , a t-SNARE protein that regulates fusion of transport vesicles with the lateral membrane domain.

290 ein required for the fusion of Golgi-derived transport vesicles with the prevacuolar/endosomal compar

291 of cadherins by linking cadherin-containing transport vesicles with the t-SNARE targeting complex.

292 fusion, autophagy and fusion of biosynthetic transport vesicles with the vacuole.

293 n the targeting and/or fusion of ER-to-Golgi transport vesicles with their acceptor compartment.

294 are believed to be involved in the fusion of transport vesicles with their target membrane.

295 to be involved in the heterotypic fusion of transport vesicles with their target membranes and the h

296 he minimal machinery that triggers fusion of transport vesicles with their target membranes.

297 been implicated in the docking and fusion of transport vesicles with their target membranes.

298 Vam2p/Vps41p is known to be required for transport vesicles with vacuolar cargo to bud from the G

299 and localizes to the Golgi apparatus and to transport vesicles within the neurites.

300 tion factors (ARFs) to facilitate coating of transport vesicles within the secretory and endosomal pa