ライフサイエンスコーパス: transporter protein

1 e surgery, immediately after DCE CT; glucose transporter protein).

2 es by heterologous expression of a bacterial transporter protein.

3 receptor 1 (FLVCR1), a gene encoding a heme-transporter protein.

4 affinity for a gene that codes for a nickel transporter protein.

5 al relationships that make CFTR a unique ABC transporter protein.

6 into bacterial cells mediated by a specific transporter protein.

7 at hSVCT2-short gave rise to a nonfunctional transporter protein.

8 uire the function of vesicular acetylcholine transporter protein.

9 lation indicating activation of pre-existing transporter protein.

10 as did deletion of the mitochondrial citrate transporter protein.

11 nsport without direct phosphorylation of the transporter protein.

12 uggests a potential function as a channel or transporter protein.

13 e regulating the steady-state level of ZnT-1 transporter protein.

14 membrane protein, while the third is an ABC-transporter protein.

15 ialMct1mRNA but increases the amount of MCT1 transporter protein.

16 hin the intronic region of SLC30A10, another transporter protein.

17 nclude important structural, regulatory, and transporter proteins.

18 ndocytosis of Tat2 and likely other membrane transporter proteins.

19 express large quantities of functional plant transporter proteins.

20 s that impact transport activity of plant Pi transporter proteins.

21 overproduction of ATP-binding cassette (ABC) transporter proteins.

22 e attributed to several multidrug resistance transporter proteins.

23 e expression of other glutamate receptor and transporter proteins.

24 g to the same family of ATP-binding cassette transporter proteins.

25 f rigidity in selective interaction with the transporter proteins.

26 and red blood cells occurs by specific urea transporter proteins.

27 e reduced product is then taken up by Fe(II) transporter proteins.

28 inner medulla was mediated by specific urea transporter proteins.

29 in III and the C-terminal domain of the TonB transporter proteins.

30 demonstrating a physical interaction between transporter proteins.

31 ith a dissociation constant typical of lipid transporter proteins.

32 characterized targets, the neurotransmitter transporter proteins.

33 ) and one minor isoform (SV2C) that resemble transporter proteins.

34 the plasma membrane by means of specialized transporter proteins.

35 s are significantly associated with membrane transporter proteins.

36 ransported by facilitated and by active urea transporter proteins.

37 ssociation rate for its interaction with the transporter proteins.

38 plants, and mammals via a family of related transporter proteins.

39 d functional studies of other Golgi membrane transporter proteins.

40 pair, and several new members of a family of transporter proteins.

41 regulated by specialized, membrane-embedded transporter proteins.

42 g the catalytic cycle, such as in enzymes or transporter proteins.

43 luding uricase and inhibitors of renal urate transporter proteins.

44 ar endothelial growth factor (VEGF), glucose transporter protein 1 (Glut-1), and hypoxia-inducible fa

45 t of GLUT 2 and the sodium-dependent glucose transporter protein 1 (SGLT1), was not regulated by lumi

46 ression) and for markers of hypoxia (glucose transporter protein 1 [Glut-1] and pimonidazole).

47 late cotransporter protein and organic anion transporter protein 1.

48 f the lipid transporter ATP-binding cassette transporter protein 12.

49 ken up by a sodium-independent organic anion transporter protein-1B1 (OATP1B1) exclusively expressed

50 ed a unique set of genes, including Receptor Transporter Protein 4 (RTP4) and STAT1, for which the ex

51 h mutations in the gene that encodes the ABC transporter protein, ABCA12.

52 ess the allelic variation of the ATP-binding transporter protein (ABCA4).

53 were examined as modulators of the membrane transporter proteins ABCB1 (P-gp), ABCG2 (BCRP), and ABC

54 n of the B subfamily of ATP-binding cassette transporter proteins (ABCBs).

55 showed that mutations in a gene encoding the transporter protein ABCC2 are linked with resistance to

56 rod outer segment ATP binding cassette (ABC) transporter protein (ABCR) plays an important role in re

57 n NaDC1 are not mediated through a change in transporter protein abundance on the plasma membrane and

58 sts that large conformational changes in the transporter protein accompany cotransport.

59 The level of transporter protein accumulation depends on the Pi conce

60 Transmembrane transporter proteins allow the passage of essentially al

61 In addition to uptake, the cloned transporter proteins also elicit ion channel-like curren

62 e content (all P < 0.001), reduced carnitine transporter protein and glycogen content, and increased

63 ently, and the effects of hypoxia on glucose transporter protein and hexokinase levels were assessed.

64 bdg encodes a novel, putative transporter protein and interacts genetically with all o

65 work is the first NMR study of a eukaryotic transporter protein and presents the power of solid-stat

66 nd has previously been shown to act as a LCB transporter protein and to be a component of the endopla

67 We studied brain sections stained for the transporter protein and/or anterogradely filled thalamoc

68 of aquaporin 1 (AQP1), AQP3, and Na-K-2Cl co-transporter proteins and a marked reduction of the urea

69 ompartment appears to involve the ABC family transporter proteins and ABC transporter inhibitor glibe

70 the largest superfamily of secondary active transporter proteins and catalyze the transport of an en

71 subpopulations, including codon variants in transporter proteins and DNA mismatch repair proteins.

72 ly of sodium-coupled bicarbonate (carbonate) transporter proteins and functions as an electrogenic so

73 he ATP-binding cassette (ABC) superfamily of transporter proteins and is highly induced when macropha

74 r-2, and mitochondrial thiamin pyrophosphate transporter proteins and messenger RNA were measured.

75 homolog of protein phosphatase 2C, a peptide transporter protein, and a nodule-specific form of cytoc

76 mitochondrial pyruvate transporter, citrate transporter protein, and citrate synthase activities.

77 -121-labeled dopamine uptake sites, dopamine transporter protein, and tyrosine hydroxylase-like immun

78 RNA binding protein families and 1777 target transporter proteins, and another sublibrary targets pro

79 secretion, in the activation of enzymes and transporter proteins, and in tissue growth.

80 d with stress responses, metabolic proteins, transporter proteins, and proteins with unknown function

81 dies have been generated to many of the urea transporter proteins, and several novel findings have re

82 mice lacking critical biosynthetic enzymes, transporter proteins, and the CysLT(1) receptor, diverse

83 signal transduction regulatory proteins, ABC transporter proteins, and the enzymes AguA (GH67 alpha-g

84 odies have been generated to the cloned urea transporter proteins, and the use of these antibodies in

85 ision of the environment for many enzyme and transporter proteins, and they influence membrane-relate

86 on of AmtB reveals that the ammonium/ammonia transporter proteins are ammonia-conducting channels rat

87 Membrane transporter proteins are essential for the maintenance o

88 t in Escherichia coli the AcrEF-TolC and Mtr transporter proteins are involved in the export and impo

89 membrane sub-domains, and symbiosis-specific transporter proteins are localized in the branch domain.

90 These transporter proteins are targetable by dietary intervent

91 The SLC26/SulP (solute carrier/sulphate transporter) proteins are a ubiquitous superfamily of se

92 the placenta and new evidence suggests that transporter proteins, as well as the regulators themselv

93 from this signature, ABCG2, which encodes a transporter protein associated with the development of d

94 gged LdNT2 revealed a marked upregulation in transporter protein at the cell surface.

95 ing and constructing transport reactions for transporter proteins based primarily on the analysis of

96 In bacteria such as Escherichia coli, transporter proteins belonging to the major facilitator

97 transporter regulation is redistribution of transporter protein between intracellular stores and the

98 egulation occurs via a redistribution of the transporter protein between the plasma membrane and the

99 Uptake of cobalamins by the transporter protein BtuB in the outer membrane of Escher

100 se iron protein and the ATP binding-cassette transporter protein, BtuCD.

101 e protein with homology to a class of solute transporter proteins, but how overexpression suppresses

102 oduced by SERT substrates are dependent upon transporter proteins, but the exact mechanisms responsib

103 n part through interactions with 4E-T (eIF4E transporter) protein, but the precise mechanism is unkno

104 f 0.93 and 0.90, respectively in identifying transporter proteins by name within the complete genome.

105 is the common mode of regulation of various transporter proteins by PKC.

106 It is distinguished from classical transporter proteins by the absence of putative hydropho

107 roduction of a plasma membrane-localized ABC transporter protein called Pdr5p.

108 activity of a vacuolar ATP-binding cassette transporter protein called Ycf1.

109 Ps in association with membrane bound copper transporter proteins cause sequestration of copper, thus

110 The ceramide transporter protein (CERT) and its longer splicing isofo

111 he solute to the periplasmic entrance of the transporter protein complex BtuCD.

112 skeletal muscle (Glut 1 and Glut 4) glucose transporter protein concentrations.

113 In biliary-diverted rats (72-96 hours), transporter protein decreased to 57% +/- 5% of paired co

114 otein was a new member of a subfamily of ABC transporter proteins defined by the multidrug resistance

115 rphology of the fusion product and regulates transporter protein degradation.

116 through cholesterol-dependent inhibition of transporter protein degradation.

117 Next, we compared the regional receptor/transporter protein densities with mRNA levels and uncov

118 A chemically postmodified transporter protein, DHSA, is fused with (imino)biotinyl

119 The divalent metal transporter protein DMT1 (also known as SLC11A2) is the

120 receding ventricular dilatation, and glucose transporter protein downregulation, glucose uptake is si

121 our laboratory recently identified the ZIP8 transporter protein, encoded by the mouse Slc39a8 gene,

122 scriptional factors (TFs), and 155 annotated transporter proteins exhibited differential expression d

123 resulted in a time-dependent reinduction of transporter protein expression (3.5-fold).

124 between flow-extraction product and glucose transporter protein expression (r = -0.50, P = .002).

125 Meldonium reduced carnitine transporter protein expression across muscles of differe

126 rotein transport activity without decreasing transporter protein expression or opening tight junction

127 oprotein transport activity without altering transporter protein expression or tight junction permeab

128 d double mutant (L243P/T262M) did not affect transporter protein expression or trafficking to the pla

129 After 6 h, transport activity and transporter protein expression was double that of contro

130 Glucose transporter protein expression was significantly lower f

131 Glucose transporter protein expression was the same in all group

132 ced riboflavin uptake and reduced riboflavin transporter protein expression, and we report the respon

133 ted negatively with pimonidazole and glucose transporter protein expression, indicating the potential

134 protein transport activity with no change in transporter protein expression.

135 es in P-glycoprotein activity independent of transporter protein expression.

136 oprotein transport activity without changing transporter protein expression.

137 rse genes fall into at least eight different transporter protein families based on sequence similarit

138 crystallization of other members of the ABC transporter protein family, including BmrA and the ATPas

139 members of the glutamate/neutral amino acid transporter protein family, SLC1.

140 on channel in the ATP-binding cassette (ABC) transporter protein family.

141 s had been previously suggested, but the ABC transporter protein FepD is required for utilization of

142 ly enhanced the adaptive upregulation of new transporter proteins for amino acids and glucose.

143 esults in the endocytosis and degradation of transporter proteins for glucose and amino acids.

144 requires translocation of the GLUT4 glucose transporter protein from intracellular storage sites to

145 We have cloned a transporter protein from rabbit small intestine, which,

146 nted the clearance of glucose and amino acid transporter proteins from the cell surface.

147 Transporter proteins from the MATE (multidrug and toxic

148 in this cluster was ABCB1 the P-glycoprotein transporter protein gene and MMP1 (Matrix Metalloprotein

149 tic polymorphism (5-HTTLPR) in the serotonin transporter protein gene on the likelihood that life str

150 tes the membrane localization of the glucose transporter proteins (Glut)1, Glut2, and Glut4, and, the

151 results in the translocation of the glucose transporter proteins GLUT1 and GLUT4 to the sarcolemma.

152 hways including translocation of the glucose transporter protein GLUT4 to the plasma membrane upon in

153 ve to the levels of the facilitative glucose transporter protein, GLUT4.

154 ng subunits I and II along with two ABC-type transporter proteins, homologs of which in other bacteri

155 SLC28 genes encode three plasma membrane transporter proteins, human concentrative nucleoside tra

156 ntrated urine and is mediated by a family of transporter proteins, identified from erythropoietic tis

157 scussed in view of the presence of manganese transporter protein in mycobacteria and macrophages wher

158 We confirmed expression of transporter protein in neurons in schizophrenia using du

159 zation of Npt2 paralleled a reduction in the transporter protein in renal brush-border membranes isol

160 eflect a compensatory downregulation of this transporter protein in response to an insufficient avail

161 Overexpression of the human GLUT1 glucose transporter protein in skeletal muscle of transgenic mic

162 was no change in vasopressin-regulated urea transporter protein in the inner medullary base, and Nor

163 es revealed a robust expression of the GLT-1 transporter protein in the SON, which was diminished in

164 ng that significant blockade of the dopamine transporter protein in the striatum is required for incr

165 ers (CNT1 and CNT2) prompted us to study the transporter proteins in 2 models of hepatocarcinogenesis

166 several key cytochrome P450 enzymes and drug transporter proteins in liver and intestine in a species

167 ound and specific downregulation of nutrient transporter proteins in mammalian cells.

168 ry of genes encoding cytoprotective and drug transporter proteins in response to chemical and radiati

169 keletal muscle controls the expression of FA transporter proteins in the capillary endothelium and th

170 Because 5-HT transporter proteins in the lung and brain are identical

171 nt to survive, they have evolved active iron transporter proteins in their outer membranes.

172 tics also affected the expression of glucose transporter proteins in whole cell extracts and at the c

173 High expression of antiapoptotic and/or drug transporter proteins induced by oncogenic signaling path

174 However, many of the transporter proteins involved have yet to be identified,

175 The CmeR-regulated genes encode membrane transporters, proteins involved in C4-dicarboxylate tran

176 de a variety of proteins, including putative transporters, proteins involved in siderophore synthesis

177 evealed that the TT8 regulome included sugar transporters, proteins involved in sugar binding and seq

178 The core of the ABC transporter protein is composed of transmembrane domains

179 histidine mutants of hPEPT1 showed that the transporter protein is expressed exclusively in the plas

180 he large-scale structural transitions of the transporter protein is indicative of imperfections in th

181 ut the definitive functional identity of the transporter protein is not known.

182 (2) The expression level of the 117-kD urea transporter protein is regulated and is inversely correl

183 cluding studies of uremic rats in which urea transporter protein is upregulated in liver and heart.

184 step in the biogenesis of this family of ABC transporter proteins is at the level of transport from t

185 iated by a family of high-affinity glutamate transporter proteins is essential to continued glutamate

186 ily of structurally related, Na(+)-dependent transporter proteins is responsible for presynaptic reup

187 oded protein, MATP (for "membrane-associated transporter protein") is predicted to span the membrane

188 e gene encoding STX6 (syntaxin 6), a vesicle transporter protein, is directly regulated by each of th

189 mber of the major facilitator superfamily of transporter proteins, is the cell surface receptor for f

190 isease anthrax, secretes two NEAT (near iron transporter) proteins, IsdX1 and IsdX2, which scavenge h

191 t are encoded in operons with the respective transporter proteins, KefB and KefC, and are required fo

192 f auxin-response components, including auxin transporters, protein kinases and phosphatases, componen

193 nstrated that the marked reduction in the co-transporter protein levels was essentially due to increa

194 Cerebral glutamate/aspartate transporter protein levels were higher in transgenic mic

195 monia-induced decline in glutamate-aspartate transporter protein levels, UO126 did not, indicating a

196 er of a large family of ATP binding cassette transporter proteins, localizes to the plasma membrane a

197 re fold previously described for lipoprotein transporter proteins LolA and LolB.

198 The magnesium transporter protein MAGT1 participates in the intracellu

199 of DOX and decreases the expression of drug transporter proteins MDR1, MRP1, and ABCG2.

200 Transporter protein, messenger RNA (mRNA), and activity

201 regulated placental expression of fatty acid transporter protein, metabolic signaling pathways (phosp

202 n after routine intravenous injection of the transporter-protein mixture.

203 This gene, termed metal transporter protein (mtp1), is expressed in tissues invo

204 ignaling regulates the expression of the ABC transporter proteins multi-drug resistance protein-1 (MD

205 that disrupt the endo/lysosomal cholesterol transporter protein Niemann-Pick C1 (NPC1).

206 he basolateral membrane Na(+)/K(+)/2Cl(-) co-transporter protein NKCC1(+), and NKCC1(-) mice were cor

207 ation in the gene encoding the putative iron transporter protein Nramp2.

208 , we investigated insulin signaling, glucose transporters, protein O-GlcNAcylation, and phosphorylati

209 es expressed the organic anion organic anion transporter protein (OATP) 2B1 transporter.

210 uggesting that constant replenishment of the transporter protein occurs; (iii) immunofluorescent stai

211 ith a 2.3 +/- 0.3-fold increase in carnitine transporter protein (OCTN2) mRNA expression (P<0.05).

212 57% similarity and 33% identity to the ComGA transporter protein of Bacillus subtilis and contained t

213 present evidence that FET4 encodes the Fe2+ transporter protein of this system.

214 otein 6 (MRP6), a putative transmembrane ABC transporter protein of unknown function, have been discl

215 on is mediated by ATP binding cassette (ABC) transporter proteins of subfamily D, which includes the

216 located in or near genes encoding metabolite transporter proteins or enzymes (SLC22A16, ARG1, AGPS an

217 no changes in the cellular levels of glucose transporter proteins or hexokinase were observed.

218 denosine triphosphate-binding cassette (ABC) transporter proteins, P-glycoprotein or breast cancer re

219 the genes encoding the ATP-binding cassette transporter proteins Pdr5 and Yor1 elevated PHS toleranc

220 rotocol yielding approximately 1.8 mg of the transporter protein per liter of E. coli culture.

221 tive CMP-sialic acid transporter encodes the transporter protein per se and suggests that this hetero

222 ncovered overrepresentation of transmembrane transporters, protein phosphatase regulators, and cytosk

223 ecifically to cells expressing the phosphate transporter protein Pit1, demonstrating for the first ti

224 ing either of two widely expressed phosphate transporter proteins, Pit1 or Pit2.

225 Alpha-helical transmembrane channel and transporter proteins play vital roles in a diverse range

226 Recent studies have shown that a specific transporter protein plays an essential role in loading s

227 n as SLC12A3), a 12-transmembrane-domain ion transporter protein preferentially expressed in the kidn

228 ising from the activity of integral membrane transporter proteins presents a global public health thr

229 ve to 37 degrees C, including genes encoding transporter proteins, proteins involved in iron homeosta

230 e through its binding with the multispecific transporter protein, Ralbp1.

231 Presynaptic transporter proteins regulate the clearance of extracell

232 ik et al. demonstrate that the STRA6 retinol transporter protein regulates the proliferation and diff

233 hes to perform integrative studies into urea transporter protein regulation, both in normal animals a

234 and cDNAs, and integrative studies into urea transporter protein regulation, both in the kidney and i

235 test QM/DMD using the Fe-containing electron transporter protein, rubredoxin, and its three mutants a

236 ed as a photoaffinity probe for the putative transporter protein(s).

237 um bicolor upregulates the membrane-embedded transporter protein SbMATE in its roots.

238 s, such as a BLAST search tool against known transporter protein sequences, comparison of transport s

239 nin and serotonergic receptors are serotonin transporter protein (SERT or soluble carrier protein, SL

240 f the gene (SLC6A4) coding for the serotonin transporter protein (SERT).

241 5-HT undergoes reuptake by a transporter protein (SERT).

242 uman renal sodium gradient-dependent glucose transporter protein (SGLT2) mRNA and protein expression

243 ng glucose reabsorption by sodium glucose co-transporter proteins (SGLTs) in the kidneys is a relativ

244 presynaptic vesicular inhibitory amino acid transporter protein showed similar expression patterns.

245 f striatal tyrosine hydroxylase and dopamine transporter proteins showed decreased expression in MPTP

246 Both transporter proteins similarly functionally complemented

247 ases (MKK7 and SNARK), and 2 closely related transporter proteins (SLC12A4 and SLC12A5).

248 The gene encoding the norepinephrine transporter protein (SLC6A2) maps to this broad region,

249 iatry-tryptophan hydroxylase (TPH), dopamine transporter protein (SLC6A3), D3 dopamine receptor (DRD3

250 dentification of the solute carrier 6 (SLC6) transporter protein SNF-10 as a key regulator of C. eleg

251 Selective inhibition of the transporter protein sodium-glucose cotransporter 2 (SGLT

252 inary studies of enterocyte brush-border ion transporter proteins (sodium hydrogen exchanger 2, sodiu

253 that SERT tyrosine phosphorylation supports transporter protein stability and 5HT transport.

254 h the overproduction of ATP-binding cassette transporter proteins such as Pdr5p or Yor1p.

255 on or overexpression of ATP-binding cassette transporter proteins such as the multidrug resistance pr

256 ficking and function of ATP-binding cassette transporter proteins, such as the CFTR and MRP.

257 vation leads to a concurrent increase in the transporter protein, suggesting a transcriptional regula

258 ce Protein (BCRP/ABCG2) is one member of ABC transporters proteins super family responsible of drug r

259 DP) that belongs to the ATP binding cassette transporter protein superfamily.

260 The glucose transporter protein syndrome (GTPS) is caused by defecti

261 the activity of the Pdr12 ABC transporter, a transporter protein that is constitutively expressed in

262 gene, which encodes an ATP binding cassette transporter protein that is required for multidrug toler

263 RLIP76 is a multifunctional transporter protein that serves as an energy-dependent e

264 342 is mediated by ATP binding cassette drug transporter proteins that also contribute to chemoresist

265 e members of the solute carrier 22 family of transporter proteins that are involved in absorption, di

266 coprotein 2 (SV2) family, which are putative transporter proteins that are predicted to have 12 trans

267 The chemical signal is terminated by transporter proteins that transfer transmitter molecules

268 are flippases, which are transmembrane lipid transporter proteins that transport phospholipids across

269 elief of repression allows expression of HXT transporter proteins, the resumption of glucose uptake a

270 encoding key metabolic enzymes and an uptake transporter protein through a network of interactions in

271 hat explains conformational transitions of a transporter protein through a series of linked equilibri

272 onfocal imaging studies showed the human TPP transporter protein to be expressed at the apical membra

273 amber codon suppression in a membrane-bound transporter protein to encode photocrosslinking unnatura

274 in part, by causing a redistribution of the transporter protein to or from the cell surface.

275 Gemcitabine requires transporter proteins to cross cell membranes.

276 r membrane vesicles containing GLUT4 glucose transporter proteins to the plasma membrane.

277 with plant infection such as hydrolases, ABC transporters, protein toxins, proteinase inhibitors, and

278 Glucose transporter protein type 1 (GLUT1) is a major glucose tr

279 terol-sensitive mechanism for suppression of transporter protein ubiquitination, which in turn decrea

280 ndolysosomal acidification and the endosomal transporter protein UNC93B1 was required for poly(I:C)-i

281 ation of M2R and the vesicular acetylcholine transporter protein (VAChT), a marker for cholinergic ax

282 odies to the presynaptic vesicular glutamate transporter protein (vGlut1) and postsynaptic NMDA recep

283 presynaptic marker, the vesicular monoamine transporter protein (VMAT2), was quantified with (+)[(11

284 Vasopressin-regulated urea transporter protein was significantly increased in both

285 t analysis showed that expression of taurine transporter protein was similar in oocytes injected with

286 The expression of zinc transporter proteins was determined by RT-PCR.

287 ted in changes in the bacterial and archaeal transporter proteins, we generated an extensive metaprot

288 ins of the Aspergillus nidulans NrtA nitrate transporter protein were altered individually by site-sp

289 mes or proteins, including HMA, YSL1 and ABC transporter protein were involved in Cr uptake and homeo

290 Changes in transporter proteins were also assessed by immunohistoch

291 Zn transporter proteins were also detected in ARPE19.

292 racterization of a mouse N-system amino acid transporter protein, which is involved in the transport

293 retina-specific ATP-binding cassette (ABCA4) transporter protein, which is responsible for a phenotyp

294 ee of which are homologous to genes encoding transporter proteins, which are likely involved in exoch

295 emic cells and the presence of transmembrane transporter proteins, which extrude certain chemotherapy

296 il helical bundles, frequent in channels and transporter proteins, which show significant helix bendi

297 ippase, is an essential ATP-binding cassette transporter protein with homology to mammalian multidrug

298 KSHV also utilizes the amino acid transporter protein xCT for infection of adherent cells,

299 The ATP binding cassette (ABC) transporter protein Yor1p was identified on the basis of

300 Stable overexpression of the transporter protein Zip2 was achieved by transducing ARP