ライフサイエンスコーパス: transposable

1 ENs) that are enriched with species-specific transposable and repetitive DNA elements.

2 RSA) strain USA500 revealed acquisition of a transposable element (IS256) that is absent from close r

3 eages have experienced differential rates of transposable element (TE) accumulation, which would be p

4 Transposable element (TE) derived sequences are known to

5 igated the relationships of gene expression, transposable element (TE) distribution and small RNA tar

6 p of its active developmental enhancers with transposable element (TE) families and compared this ove

7 mined gene expression, gene methylation, and transposable element (TE) methylation in a natural, <140

8 to specifically target and cleave endogenous transposable element (TE) mRNAs produced from transcript

9 enes, many of these sRNAs are generated from transposable element (TE) regions, which are likely to c

10 etic silencing of a new transgene, virus, or transposable element (TE) remains enigmatic.

11 Transposable element (TE) silencing is initiated early i

12 nzymes predicted to have been derived from a transposable element (TE) that invaded an immunoglobulin

13 Loss of PAF1 suppresses endogenous transposable element (TE) transcript maturation, whereas

14 Although there are several examples of transposable element (TE)-derived insulators, the contri

15 predominant plasmid (pKpQIL), and a specific transposable element (Tn4401, 10 kb).

16 r levels of gene expression, higher rates of transposable element accumulation, more small interferin

17 However, transposable element activity can lead to detrimental ge

18 this genome revealed long-lasting and recent transposable element activity predominately driven by Gy

19 evolutionary conserved mechanisms to silence transposable element activity, there are drastic differe

20 only 25 genes were associated with a nearby transposable element and NRPE1- and/or ROS1-controlled D

21 H. bogdanii had been interrupted by a native transposable element and was surrounded by about 70 kbp

22 e a species-wide view of the activity of one transposable element at unprecedented resolution, showin

23 dissect the mode of action of the carbonaria transposable element by showing that it increases the ab

24 including nucleotide substitutions, indels, transposable element content and movement, gene family e

25 In this article, we present a new transposable element de novo assembler, Tedna, which ass

26 Gene and transposable element density across the B. napus genome

27 Here, we identify the piggyBac transposable element derived 5 (PGBD5) gene as encoding

28 We have used the newly engineered transposable element Dsg to tag a gene that gives rise t

29 rrangements that are closely associated with transposable element expansions.

30 ombinatorial patterns, suggesting that these transposable element families play an important role in

31 copy, and phenotypical characterization of a Transposable Element from Nicotiana tabacum (Tnt1) inser

32 chromines, but not other cichlids, feature a transposable element in the cis-regulatory region of fhl

33 alyses of the genome and detailed history of transposable element insertion events.

34 We found a miniature inverted-repeat transposable element insertion in the promoter region of

35 Finally, genetic variation based on the transposable element insertion pattern was investigated

36 ed epiTEome, a program that detects both new transposable element insertion sites and their methylati

37 riation, including tandem duplications and a transposable element insertion that amplifies the expres

38 into non-satellite DNA, typically defined by transposable element insertion.

39 enomic organization, transcription patterns, transposable element insertions and phylogenetic analyse

40 ution, expression divergence associated with transposable element insertions, and regulation by novel

41 es through the accumulation of deletions and transposable element insertions, whereas FDY remained fu

42 the insertion of a large, tandemly repeated, transposable element into the first intron of the gene c

43 ansposable elements, allowing us to identify transposable element lineage expansions that are unique

44 and hosts have evolved mechanisms to silence transposable element mobility appropriately.

45 hanism functions through RNAi degradation of transposable element mRNAs into small RNAs guided by the

46 ylation levels has been limited to reference transposable element positions.

47 gnificantly hypomethylated and include fewer transposable element sequences relative to non-NAT genes

48 percent of the human genome is comprised of transposable element sequences, and the most abundant cu

49 Here we report the knockout of TRANSPOSABLE ELEMENT SILENCING VIA AT-HOOK (TEK) leads t

50 RNA polymerase IV to reinforce pre-existing transposable element silencing.

51 ue opportunity to understand the dynamics of transposable element spread and the associated piwi-inte

52 INE-1 (long interspersed element 1, L1) is a transposable element that has extensively colonized the

53 Furthermore, we discovered a transposable element that resides immediately upstream o

54 onents regulate precursor mRNA splicing of P-transposable element transcripts in vivo, leading to the

55 Intriguingly, most of the transposable element transcripts maintained a fragmented

56 s and use guide piRNAs to target and destroy transposable element transcripts.

57 The discovery that the mutation itself is a transposable element will stimulate further debate about

58 An intronic, transposable element within SMOC2 promotes the utilizati

59 RAG1/2 are proposed to have arisen from a transposable element, but definitive evidence for this i

60 1 and RAG2 are thought to have arisen from a transposable element, but the origins of this element ar

61 convergently overlapped gene and associated transposable element, may contribute to the generation o

62 man PGBD5, the most evolutionarily conserved transposable element-derived gene in vertebrates, can in

63 s, we observe that the putative Mutator-like transposable element-derived genes are generally GC-rich

64 sive expression environment for newly formed/transposable element-derived genes.

65 transition, as based on the reactivation of transposable element-driven reporter genes.

66 signal, and vicinity to a "miniature impala" transposable element.

67 to genomic rearrangements likely caused by a transposable element.

68 Miniature inverted repeat transposable elements (MITEs) are prevalent in eukaryoti

69 Miniature inverted repeat transposable elements (MITEs) are prevalent in eukaryoti

70 Stowaway family of miniature inverted-repeat transposable elements (MITEs).

71 Mutator-like transposable elements (MULEs) are widespread across fung

72 Mutator-like transposable elements (MULEs) are widespread in plants a

73 Transposable elements (TE) have both negative and positi

74 Insertions and excisions of transposable elements (TEs) affect both the stability an

75 Transposable elements (TEs) allow rewiring of regulatory

76 We found that ROS1 preferentially targets transposable elements (TEs) and intergenic regions.

77 Transposable elements (TEs) and repetitive DNA make up a

78 Transposable elements (TEs) and repetitive sequences are

79 disiRNAs originate mostly from transposable elements (TEs) and TE-overlapping/proximal

80 latory variation, whereas presence of nearby transposable elements (TEs) and tissue specificity of ex

81 organization is largely due to variation in transposable elements (TEs) and whole-genome duplication

82 ten being classified as selfish or junk DNA, transposable elements (TEs) are a group of abundant gene

83 Transposable elements (TEs) are a prolific source of tig

84 Remnants of ancient transposable elements (TEs) are abundant in mammalian ge

85 Transposable elements (TEs) are both a boon and a bane t

86 Transposable elements (TEs) are DNA sequences that are a

87 Transposable elements (TEs) are mobile genetic elements,

88 Transposable elements (TEs) are mobile genomic DNA seque

89 Transposable elements (TEs) are mobile units of DNA that

90 Transposable elements (TEs) are powerful motors of genom

91 Transposable elements (TEs) are repeated DNA sequences t

92 Transposable elements (TEs) are selfish genetic units th

93 Transposable elements (TEs) are silenced in germ cells b

94 Transposable elements (TEs) are uniquely equipped to dep

95 In many eukaryotic genomes, transposable elements (TEs) are widely distributed and o

96 Transposable elements (TEs) are widespread genomic paras

97 ting the expression of both coding genes and transposable elements (TEs) between hybrid sterile males

98 Recent studies have shown that transposable elements (TEs) can also mediate recurrent d

99 Transposable elements (TEs) can be found in virtually al

100 It is well documented that transposable elements (TEs) can regulate the expression

101 Genomic transposable elements (TEs) comprise nearly half of the

102 Transposable elements (TEs) constitute the most active,

103 Transposable elements (TEs) contribute to the large amou

104 s and Piwi-interacting RNAs (piRNAs) repress transposable elements (TEs) from mobilizing in gonadal c

105 Transposable elements (TEs) generate mutations and chrom

106 Transposable elements (TEs) have been shown to contain f

107 Transposable elements (TEs) have had a major influence o

108 its structure suggests a fundamental role of transposable elements (TEs) in adaptive evolution.

109 Studies of the population dynamics of transposable elements (TEs) in Drosophila melanogaster i

110 Small RNAs are used to silence transposable elements (TEs) in many eukaryotes, which us

111 n this study, we focused on the evolution of transposable elements (TEs) in relation to the genome si

112 ll noncoding RNAs that control expression of transposable elements (TEs) in the Drosophila germline.

113 Variation in the presence or absence of transposable elements (TEs) is a major source of genetic

114 In eukaryotes, aberrant expression of transposable elements (TEs) is detrimental to the host g

115 The mobilization of transposable elements (TEs) is suppressed by host genome

116 Transposable elements (TEs) make up a large proportion o

117 Transposable elements (TEs) occupy a large fraction of m

118 es account for 67.2% of the AtDt genome, and transposable elements (TEs) originating from Dt seem mor

119 Transposable elements (TEs) proliferate within the genom

120 Transposable elements (TEs) represent the single largest

121 The excision and reintegration of transposable elements (TEs) restructure their host genom

122 rt Interspersed Nuclear Elements (SINEs) are transposable elements (TEs) that amplify through a copy-

123 (piRNAs) protect the germ line by targeting transposable elements (TEs) through the base-pair comple

124 all RNAs, plays a major role in silencing of transposable elements (TEs) to maintain genome integrity

125 It is hypermethylated within transposable elements (TEs), accompanied by increased ab

126 ndogenous gene expression, controls invading transposable elements (TEs), and protects the cell again

127 recognition and transcriptional silencing of transposable elements (TEs), consistent with an 'arms ra

128 We map the evolutionary trajectories of transposable elements (TEs), developmental genes and sex

129 Newly evolved CREs are enriched in young transposable elements (TEs), including Long-Terminal-Rep

130 hroughout the entire seed, targets primarily transposable elements (TEs), is maintained during endore

131 Repetitive DNA, especially that due to transposable elements (TEs), makes up a large fraction o

132 hypomethylation of protein-coding genes and transposable elements (TEs), preferentially those adjace

133 titive DNA elements, repress mobilization of transposable elements (TEs), template or bridge DNA doub

134 e comprised of repetitive sequences, such as transposable elements (TEs), which have been implicated

135 These regions are often occupied by transposable elements (TEs), which make up between 20 an

136 ation, little is known about their effect on transposable elements (TEs), which make up nearly half o

137 Half the human genome is made of transposable elements (TEs), whose ongoing activity cont

138 ensation and transcriptional reactivation of transposable elements (TEs).

139 rity of HTs reported so far are transfers of transposable elements (TEs).

140 alian genomes and are frequently enriched in transposable elements (TEs).

141 ess parasitic mobile sequences of DNA called transposable elements (TEs).

142 and transcriptional gene silencing (TGS) of transposable elements (TEs).

143 ads to risk of transcriptional activation of transposable elements (TEs).

144 s central to controlling the mobilization of transposable elements (TEs).

145 f parental alleles, particularly at proximal transposable elements (TEs).

146 utilizes the termini of two separate, nearby transposable elements (TEs).

147 elanogaster, where it acts to silence active transposable elements (TEs).

148 ghlighting the diversity and distribution of transposable elements (TEs).

149 mportant role in the regulation of genes and transposable elements (TEs); however, the role of DNA me

150 The maize genome has a high number of transposable elements (TEs; almost 85%), some of which s

151 malian genome is noncoding, and interspersed transposable elements account for approximately 50% of n

152 ays act at the front line of defence against transposable elements across the Eukaryota.

153 gesting that the host epigenetic response to transposable elements also affects genes.

154 re, Zfrp8 regulates the activity of specific transposable elements also controlled by Maelstrom and P

155 a sequence-independent RNAi response against transposable elements amplifying within the genome.

156 lay faster evolutionary rates, lie closer to transposable elements and are less likely to be syntenic

157 me size evolution illustrate the key role of transposable elements and chromosome rearrangements in d

158 We also provide a summary of transposable elements and contrast these with the rhesus

159 mosome painting revealed the distribution of transposable elements and differentiated chromosome bloc

160 A small number of transposable elements and genes had reduced DNA methylat

161 an play important roles in the regulation of transposable elements and genes.

162 lay a crucial role in genome defense against transposable elements and guide Argonaute proteins to na

163 residues regulates gene expression, silences transposable elements and influences genome stability.

164 New insertions of IS1236 transposable elements and IS1236-mediated deletions led

165 This enabled identification of both transposable elements and meiotically expressed protein-

166 Our results suggest that eliminating transposable elements and other genetic failure modes th

167 y had a very modest effect on the release of transposable elements and other heterochromatic transcri

168 We emphasize the role of transposable elements and other repeat sequences in the

169 ic sequences such as centromeres, telomeres, transposable elements and rRNA clusters that are typical

170 itical role in the regulation of transgenes, transposable elements and some endogenous genes; however

171 dy, changes in the amount of repetitive DNA (transposable elements and tandem repeats) are primarily

172 In the ciliate Paramecium, transposable elements and their single-copy remnants are

173 sified into two types: those containing LINE transposable elements and those containing segmental dup

174 associated with transcriptional silencing of transposable elements and transcript abundance of genes

175 lation occurs in and around genes as well as transposable elements and undergoes global reprogramming

176 gh proportions of transposable elements, and transposable elements appear to be a major force behind

177 ic tools and mutagenesis strategies based on transposable elements are currently under development wi

178 utants that distinguish RdDM mechanisms when transposable elements are either transcriptionally silen

179 Repressive chromatin marks (H3K9me2/3) and transposable elements are enriched at demethylation-resi

180 Transposable elements are found throughout the genomes o

181 Transposable elements are major evolutionary forces whic

182 iRNAs and other small RNA pathways targeting transposable elements are poorly resolved.

183 A large number of transposable elements are predicted in the E. granulatus

184 Transposable elements associated with siRNA clusters had

185 ions such as DNA methylation are targeted to transposable elements by small RNAs in a process termed

186 Transposable elements can drive genome evolution, but th

187 Furthermore, we determine that Mutator-like transposable elements capture parental sequences prefere

188 Transposable elements comprise roughly 40% of mammalian

189 o assembler, Tedna, which assembles a set of transposable elements directly from the reads.

190 We show that several families of transposable elements disproportionally overlap with enh

191 d that RDR6-RdDM preferentially targets long transposable elements due to the specificity of primary

192 Acquisition of ssa and transposable elements encoding multidrug resistance gene

193 are drastic differences in the abundance of transposable elements even among closely related plant s

194 Few de novo assemblers for transposable elements exist, and most have either been d

195 e, base-pairing between highly complementary transposable elements facilitates backsplicing.

196 r stress tolerance and provide evidence that transposable elements had a role in the evolution of the

197 ylation analysis of non-reference and mobile transposable elements has only recently been performed,

198 n and Galaxy empower researchers to identify transposable elements in a graphical user interface with

199 Phage Mu is unique among transposable elements in employing a transposition enhan

200 or an adaptable immune system that represses transposable elements in germ cells of Metazoa.

201 s, serve as guides for repression of diverse transposable elements in germ cells of metazoa.

202 Physiology or Medicine for her discovery of transposable elements in maize.

203 The de novo silencing of transposable elements in plants and animals is mediated

204 re the smallest but most abundant autonomous transposable elements in prokaryotic genomes, which play

205 ve important implications in reactivation of transposable elements in prostate cancer cells.

206 ence (RNAi) pathway that targets viruses and transposable elements in somatic tissues.

207 of putative genes derived from Mutator-like transposable elements in ten Oryza species and the outgr

208 (piRNAs) act as an immune system to suppress transposable elements in the animal gonads.

209 The role of transposable elements in the expansion of nucleotide-bin

210 Transposable elements in the genome are generally silenc

211 ing RNAs (piRNAs) have been shown to repress transposable elements in the germline and, hence, have b

212 The piRNA pathway represses transposable elements in the gonads and thereby plays a

213 particular, we reveal significant impact of transposable elements on the epigenetic regulatory lands

214 h highly derived roles in the suppression of transposable elements or meiotic drive.

215 major influence in population genetics, and transposable elements play a key role in pan-genome evol

216 The few transposable elements present are mainly ancient, inacti

217 Insertion sequences (ISs) are transposable elements present in most bacterial and arch

218 is and shows an increased genome size due to transposable elements proliferation.

219 We show that transcription of transposable elements provides a sensitive measure of th

220 as investigated to elucidate the features of transposable elements related to blue egg shell formatio

221 y and illustrate how epigenetic silencing of transposable elements rewires host gene expression progr

222 his method to the study of the spread of the transposable elements ROO, GYPSY and DM412 on a chromoso

223 a small set of lncRNAs appears enriched for transposable elements suggesting a selective pressure ac

224 hat putative genes derived from Mutator-like transposable elements tend to be expressed in mature pol

225 mid north-facing slope carried about 6% more transposable elements than those from the hot and dry so

226 L1 retrotransposons are an abundant class of transposable elements that pose a threat to genome stabi

227 e frequently associated with the presence of transposable elements that preferentially belong to heli

228 n of genes or their regulatory elements, and transposable elements themselves can act as alternative

229 A clusters resulted in lower activity of the transposable elements through DNA methylation in the hyb

230 establishes and maintains DNA methylation at transposable elements to ensure genome stability in plan

231 that LTR/Gypsy and LTR/Copia were two major transposable elements within the intronic polyadenylatio

232 gration sites of retroviruses(2-6) and other transposable elements(7-9), and it has been suggested th

233 persed with middle repetitive DNA sequences (transposable elements).

234 Mutator-like transposable elements, a class of DNA transposons, exist

235 the genome revealed more than 130,000 intact transposable elements, allowing us to identify transposa

236 Transposable elements, also known as transposons, are no

237 d correctly assembles gene cassettes, rRNAs, transposable elements, and other genomic features that w

238 Some genomes contain high proportions of transposable elements, and transposable elements appear

239 ci would allow suppression of newly emerging transposable elements, but such a surveillance system re

240 iRNA) pathway is vital for the regulation of transposable elements, by inducing transcriptional silen

241 ential are the evolution of sex chromosomes, transposable elements, deleterious mutations, sexual rep

242 enomic blocks, asymmetrical amplification of transposable elements, differential gene co-retention fo

243 t studies have demonstrated that a subset of transposable elements, endogenous retroviral elements (E

244 re associated with miniature inverted-repeat transposable elements, imprinted differentially methylat

245 Transposable elements, including endogenous retroviruses

246 This work is relevant to all transposable elements, including retroviral elements lik

247 of RdDM function on over 20 % of transcribed transposable elements, including the majority of full-le

248 which are largely noncoding transcripts and transposable elements, stimulates the pattern recognitio

249 to full-length and transcriptionally active transposable elements, suggesting that these pathways ar

250 n, age, and diversity of the highly abundant transposable elements, the primary factor determining ge

251 Classified as a type of non-autonomous DNA transposable elements, they play important roles in geno

252 egulation of genes derived from Mutator-like transposable elements, thus contributing to the evolutio

253 influence of bidirectional transcription and transposable elements, two pervasive features of vertebr

254 By studying subgroups of transposable elements, we also found that non-CpG methyl

255 preferentially enriched on edges of silenced transposable elements, where Pol V transcribes into TEs.

256 the accumulation of toxic transcripts of Alu transposable elements, which activate the NLRP3 inflamma

257 The cells contain tens of transposable elements, which likely cause the unpreceden

258 mplex organization of interspersed genes and transposable elements, which necessitates frequent bound

259 thers; the phasiRNAs are predicted to target transposable elements, with their peak abundance during

260 erspersed repeats reflecting the activity of transposable elements.

261 nitiate and re-establish silencing of active transposable elements.

262 A large majority of new enhancers comprise transposable elements.

263 onversion and increased rates of fixation of transposable elements.

264 mes, marked by distinct families of 'fossil' transposable elements.

265 sociated with cis genomic features including transposable elements.

266 -dependent RNA polymerase pathway to control transposable elements.

267 and decreases in diversity and abundance of transposable elements.

268 regulating gene expression and silencing of transposable elements.

269 novel promoters coincide with MaLR and ERVK transposable elements.

270 y inactivating invasive genetic material and transposable elements.

271 intermingled with gene-coding sequences and transposable elements.

272 ent is one of the best understood eukaryotic transposable elements.

273 mmunity, gene regulation and protection from transposable elements.

274 ation with particularly high activity around transposable elements.

275 n-coding genes, 1938 pseudogenes, and 85% of transposable elements.

276 for de novo assembly, and forms full-length transposable elements.

277 ases and ribonuclear RNA-binding protein and transposable elements.

278 ive with 74.4% of its content in the form of transposable elements.

279 ion of gene expression and the repression of transposable elements.

280 t the evolutionarily younger and more active transposable elements.

281 man and mouse transcripts are initiated from transposable elements.

282 esponded to transcription factors and 3 % to transposable elements.

283 onal splicing in order to detect and silence transposable elements.

284 c changes in methylation mainly occur within transposable elements.

285 e organized into large arrays interrupted by transposable elements.

286 ells activate expression of primate-specific transposable elements.

287 ciated with the transcriptional silencing of transposable elements.

288 uarius silence overlapping sets of genes and transposable elements.

289 f bacterial communities, and contain tens of transposable elements.

290 rity of the animal germline from deleterious transposable elements.

291 lly when they involve sequences derived from transposable elements.

292 iwi ribonucleoproteins (piRNPs) that silence transposable elements.

293 f proliferation and loss of lineage-specific transposable elements; and (3) that various classes of s

294 w cellular interaction between the infecting transposable phage Mu and the host Escherichia coli repl

295 The genome of transposable phage Mu is packaged as a linear segment, f

296 fibrosis (CF) lung infections, including the transposable phage, 4, which is closely related to phage

297 Temperate phages, and in particular transposable phages, are therefore likely to facilitate

298 ML and breast cancer respectively, a genomic transposable short form of human WNT10B (ht-WNT10B).

299 udy, we believe that the insights gained are transposable to other group 9 transition metals and pave

300 age small diffusible molecules, which can be transposable to other symbiotic systems.