ライフサイエンスコーパス: transposable element

1 persed with middle repetitive DNA sequences (transposable elements).

2 signal, and vicinity to a "miniature impala" transposable element.

3 to genomic rearrangements likely caused by a transposable element.

4 erspersed repeats reflecting the activity of transposable elements.

5 nitiate and re-establish silencing of active transposable elements.

6 A large majority of new enhancers comprise transposable elements.

7 onversion and increased rates of fixation of transposable elements.

8 mes, marked by distinct families of 'fossil' transposable elements.

9 sociated with cis genomic features including transposable elements.

10 -dependent RNA polymerase pathway to control transposable elements.

11 and decreases in diversity and abundance of transposable elements.

12 regulating gene expression and silencing of transposable elements.

13 novel promoters coincide with MaLR and ERVK transposable elements.

14 y inactivating invasive genetic material and transposable elements.

15 intermingled with gene-coding sequences and transposable elements.

16 ent is one of the best understood eukaryotic transposable elements.

17 mmunity, gene regulation and protection from transposable elements.

18 ation with particularly high activity around transposable elements.

19 n-coding genes, 1938 pseudogenes, and 85% of transposable elements.

20 for de novo assembly, and forms full-length transposable elements.

21 ases and ribonuclear RNA-binding protein and transposable elements.

22 ion of gene expression and the repression of transposable elements.

23 ive with 74.4% of its content in the form of transposable elements.

24 t the evolutionarily younger and more active transposable elements.

25 man and mouse transcripts are initiated from transposable elements.

26 esponded to transcription factors and 3 % to transposable elements.

27 n of a long dsRNA trigger mediated by Hoppel transposable elements.

28 genome size as a consequence of activity of transposable elements.

29 onal splicing in order to detect and silence transposable elements.

30 c changes in methylation mainly occur within transposable elements.

31 e organized into large arrays interrupted by transposable elements.

32 ells activate expression of primate-specific transposable elements.

33 ciated with the transcriptional silencing of transposable elements.

34 uarius silence overlapping sets of genes and transposable elements.

35 f bacterial communities, and contain tens of transposable elements.

36 rity of the animal germline from deleterious transposable elements.

37 lly when they involve sequences derived from transposable elements.

38 iwi ribonucleoproteins (piRNPs) that silence transposable elements.

39 gration sites of retroviruses(2-6) and other transposable elements(7-9), and it has been suggested th

40 Mutator-like transposable elements, a class of DNA transposons, exist

41 malian genome is noncoding, and interspersed transposable elements account for approximately 50% of n

42 r levels of gene expression, higher rates of transposable element accumulation, more small interferin

43 ays act at the front line of defence against transposable elements across the Eukaryota.

44 However, transposable element activity can lead to detrimental ge

45 this genome revealed long-lasting and recent transposable element activity predominately driven by Gy

46 evolutionary conserved mechanisms to silence transposable element activity, there are drastic differe

47 the genome revealed more than 130,000 intact transposable elements, allowing us to identify transposa

48 gesting that the host epigenetic response to transposable elements also affects genes.

49 re, Zfrp8 regulates the activity of specific transposable elements also controlled by Maelstrom and P

50 Transposable elements, also known as transposons, are no

51 a sequence-independent RNAi response against transposable elements amplifying within the genome.

52 only 25 genes were associated with a nearby transposable element and NRPE1- and/or ROS1-controlled D

53 H. bogdanii had been interrupted by a native transposable element and was surrounded by about 70 kbp

54 lay faster evolutionary rates, lie closer to transposable elements and are less likely to be syntenic

55 me size evolution illustrate the key role of transposable elements and chromosome rearrangements in d

56 We also provide a summary of transposable elements and contrast these with the rhesus

57 mosome painting revealed the distribution of transposable elements and differentiated chromosome bloc

58 ics reshaped by independent proliferation of transposable elements and elimination between the two ge

59 A small number of transposable elements and genes had reduced DNA methylat

60 an play important roles in the regulation of transposable elements and genes.

61 lay a crucial role in genome defense against transposable elements and guide Argonaute proteins to na

62 residues regulates gene expression, silences transposable elements and influences genome stability.

63 New insertions of IS1236 transposable elements and IS1236-mediated deletions led

64 This enabled identification of both transposable elements and meiotically expressed protein-

65 Our results suggest that eliminating transposable elements and other genetic failure modes th

66 y had a very modest effect on the release of transposable elements and other heterochromatic transcri

67 We emphasize the role of transposable elements and other repeat sequences in the

68 Eukaryotic genomes harbor transposable elements and other repetitive sequences tha

69 ic sequences such as centromeres, telomeres, transposable elements and rRNA clusters that are typical

70 itical role in the regulation of transgenes, transposable elements and some endogenous genes; however

71 dy, changes in the amount of repetitive DNA (transposable elements and tandem repeats) are primarily

72 In the ciliate Paramecium, transposable elements and their single-copy remnants are

73 sified into two types: those containing LINE transposable elements and those containing segmental dup

74 associated with transcriptional silencing of transposable elements and transcript abundance of genes

75 lation occurs in and around genes as well as transposable elements and undergoes global reprogramming

76 d correctly assembles gene cassettes, rRNAs, transposable elements, and other genomic features that w

77 Some genomes contain high proportions of transposable elements, and transposable elements appear

78 f proliferation and loss of lineage-specific transposable elements; and (3) that various classes of s

79 gh proportions of transposable elements, and transposable elements appear to be a major force behind

80 ic tools and mutagenesis strategies based on transposable elements are currently under development wi

81 utants that distinguish RdDM mechanisms when transposable elements are either transcriptionally silen

82 Repressive chromatin marks (H3K9me2/3) and transposable elements are enriched at demethylation-resi

83 Transposable elements are found throughout the genomes o

84 Transposable elements are major evolutionary forces whic

85 iRNAs and other small RNA pathways targeting transposable elements are poorly resolved.

86 A large number of transposable elements are predicted in the E. granulatus

87 Transposable elements associated with siRNA clusters had

88 e a species-wide view of the activity of one transposable element at unprecedented resolution, showin

89 RAG1/2 are proposed to have arisen from a transposable element, but definitive evidence for this i

90 1 and RAG2 are thought to have arisen from a transposable element, but the origins of this element ar

91 ci would allow suppression of newly emerging transposable elements, but such a surveillance system re

92 dissect the mode of action of the carbonaria transposable element by showing that it increases the ab

93 ions such as DNA methylation are targeted to transposable elements by small RNAs in a process termed

94 iRNA) pathway is vital for the regulation of transposable elements, by inducing transcriptional silen

95 Transposable elements can drive genome evolution, but th

96 Furthermore, we determine that Mutator-like transposable elements capture parental sequences prefere

97 Transposable elements comprise roughly 40% of mammalian

98 including nucleotide substitutions, indels, transposable element content and movement, gene family e

99 In this article, we present a new transposable element de novo assembler, Tedna, which ass

100 ential are the evolution of sex chromosomes, transposable elements, deleterious mutations, sexual rep

101 Gene and transposable element density across the B. napus genome

102 Here, we identify the piggyBac transposable element derived 5 (PGBD5) gene as encoding

103 man PGBD5, the most evolutionarily conserved transposable element-derived gene in vertebrates, can in

104 s, we observe that the putative Mutator-like transposable element-derived genes are generally GC-rich

105 sive expression environment for newly formed/transposable element-derived genes.

106 enomic blocks, asymmetrical amplification of transposable elements, differential gene co-retention fo

107 o assembler, Tedna, which assembles a set of transposable elements directly from the reads.

108 We show that several families of transposable elements disproportionally overlap with enh

109 transition, as based on the reactivation of transposable element-driven reporter genes.

110 We have used the newly engineered transposable element Dsg to tag a gene that gives rise t

111 d that RDR6-RdDM preferentially targets long transposable elements due to the specificity of primary

112 Acquisition of ssa and transposable elements encoding multidrug resistance gene

113 t studies have demonstrated that a subset of transposable elements, endogenous retroviral elements (E

114 are drastic differences in the abundance of transposable elements even among closely related plant s

115 Few de novo assemblers for transposable elements exist, and most have either been d

116 rrangements that are closely associated with transposable element expansions.

117 e, base-pairing between highly complementary transposable elements facilitates backsplicing.

118 ombinatorial patterns, suggesting that these transposable element families play an important role in

119 copy, and phenotypical characterization of a Transposable Element from Nicotiana tabacum (Tnt1) inser

120 riment where students experience how virtual transposable elements from rice (Oryza sativa) are assay

121 r stress tolerance and provide evidence that transposable elements had a role in the evolution of the

122 ylation analysis of non-reference and mobile transposable elements has only recently been performed,

123 re associated with miniature inverted-repeat transposable elements, imprinted differentially methylat

124 chromines, but not other cichlids, feature a transposable element in the cis-regulatory region of fhl

125 n and Galaxy empower researchers to identify transposable elements in a graphical user interface with

126 Phage Mu is unique among transposable elements in employing a transposition enhan

127 or an adaptable immune system that represses transposable elements in germ cells of Metazoa.

128 s, serve as guides for repression of diverse transposable elements in germ cells of metazoa.

129 Physiology or Medicine for her discovery of transposable elements in maize.

130 The de novo silencing of transposable elements in plants and animals is mediated

131 re the smallest but most abundant autonomous transposable elements in prokaryotic genomes, which play

132 ve important implications in reactivation of transposable elements in prostate cancer cells.

133 ence (RNAi) pathway that targets viruses and transposable elements in somatic tissues.

134 of putative genes derived from Mutator-like transposable elements in ten Oryza species and the outgr

135 (piRNAs) act as an immune system to suppress transposable elements in the animal gonads.

136 The role of transposable elements in the expansion of nucleotide-bin

137 Transposable elements in the genome are generally silenc

138 ing RNAs (piRNAs) have been shown to repress transposable elements in the germline and, hence, have b

139 The piRNA pathway represses transposable elements in the gonads and thereby plays a

140 Transposable elements, including endogenous retroviruses

141 This work is relevant to all transposable elements, including retroviral elements lik

142 of RdDM function on over 20 % of transcribed transposable elements, including the majority of full-le

143 alyses of the genome and detailed history of transposable element insertion events.

144 We found a miniature inverted-repeat transposable element insertion in the promoter region of

145 Finally, genetic variation based on the transposable element insertion pattern was investigated

146 ed epiTEome, a program that detects both new transposable element insertion sites and their methylati

147 riation, including tandem duplications and a transposable element insertion that amplifies the expres

148 into non-satellite DNA, typically defined by transposable element insertion.

149 enomic organization, transcription patterns, transposable element insertions and phylogenetic analyse

150 ution, expression divergence associated with transposable element insertions, and regulation by novel

151 es through the accumulation of deletions and transposable element insertions, whereas FDY remained fu

152 the insertion of a large, tandemly repeated, transposable element into the first intron of the gene c

153 RSA) strain USA500 revealed acquisition of a transposable element (IS256) that is absent from close r

154 ansposable elements, allowing us to identify transposable element lineage expansions that are unique

155 convergently overlapped gene and associated transposable element, may contribute to the generation o

156 Miniature inverted repeat transposable elements (MITEs) are prevalent in eukaryoti

157 Miniature inverted repeat transposable elements (MITEs) are prevalent in eukaryoti

158 Stowaway family of miniature inverted-repeat transposable elements (MITEs).

159 and hosts have evolved mechanisms to silence transposable element mobility appropriately.

160 hanism functions through RNAi degradation of transposable element mRNAs into small RNAs guided by the

161 Mutator-like transposable elements (MULEs) are widespread across fung

162 Mutator-like transposable elements (MULEs) are widespread in plants a

163 particular, we reveal significant impact of transposable elements on the epigenetic regulatory lands

164 h highly derived roles in the suppression of transposable elements or meiotic drive.

165 major influence in population genetics, and transposable elements play a key role in pan-genome evol

166 ylation levels has been limited to reference transposable element positions.

167 The few transposable elements present are mainly ancient, inacti

168 Insertion sequences (ISs) are transposable elements present in most bacterial and arch

169 is and shows an increased genome size due to transposable elements proliferation.

170 We show that transcription of transposable elements provides a sensitive measure of th

171 as investigated to elucidate the features of transposable elements related to blue egg shell formatio

172 y and illustrate how epigenetic silencing of transposable elements rewires host gene expression progr

173 his method to the study of the spread of the transposable elements ROO, GYPSY and DM412 on a chromoso

174 gnificantly hypomethylated and include fewer transposable element sequences relative to non-NAT genes

175 percent of the human genome is comprised of transposable element sequences, and the most abundant cu

176 Here we report the knockout of TRANSPOSABLE ELEMENT SILENCING VIA AT-HOOK (TEK) leads t

177 RNA polymerase IV to reinforce pre-existing transposable element silencing.

178 ue opportunity to understand the dynamics of transposable element spread and the associated piwi-inte

179 which are largely noncoding transcripts and transposable elements, stimulates the pattern recognitio

180 a small set of lncRNAs appears enriched for transposable elements suggesting a selective pressure ac

181 to full-length and transcriptionally active transposable elements, suggesting that these pathways ar

182 eages have experienced differential rates of transposable element (TE) accumulation, which would be p

183 Transposable element (TE) derived sequences are known to

184 igated the relationships of gene expression, transposable element (TE) distribution and small RNA tar

185 p of its active developmental enhancers with transposable element (TE) families and compared this ove

186 mined gene expression, gene methylation, and transposable element (TE) methylation in a natural, <140

187 to specifically target and cleave endogenous transposable element (TE) mRNAs produced from transcript

188 enes, many of these sRNAs are generated from transposable element (TE) regions, which are likely to c

189 etic silencing of a new transgene, virus, or transposable element (TE) remains enigmatic.

190 Transposable element (TE) silencing is initiated early i

191 nzymes predicted to have been derived from a transposable element (TE) that invaded an immunoglobulin

192 Loss of PAF1 suppresses endogenous transposable element (TE) transcript maturation, whereas

193 Although there are several examples of transposable element (TE)-derived insulators, the contri

194 t proportion of eukaryote genomes consist of transposable element (TE)-derived sequence.

195 Transposable elements (TE) have both negative and positi

196 hat putative genes derived from Mutator-like transposable elements tend to be expressed in mature pol

197 Insertions and excisions of transposable elements (TEs) affect both the stability an

198 Transposable elements (TEs) allow rewiring of regulatory

199 We found that ROS1 preferentially targets transposable elements (TEs) and intergenic regions.

200 Transposable elements (TEs) and repetitive DNA make up a

201 Transposable elements (TEs) and repetitive sequences are

202 disiRNAs originate mostly from transposable elements (TEs) and TE-overlapping/proximal

203 latory variation, whereas presence of nearby transposable elements (TEs) and tissue specificity of ex

204 organization is largely due to variation in transposable elements (TEs) and whole-genome duplication

205 ten being classified as selfish or junk DNA, transposable elements (TEs) are a group of abundant gene

206 Transposable elements (TEs) are a prolific source of tig

207 Remnants of ancient transposable elements (TEs) are abundant in mammalian ge

208 Transposable elements (TEs) are both a boon and a bane t

209 Transposable elements (TEs) are DNA sequences that are a

210 Transposable elements (TEs) are mobile genetic elements,

211 Transposable elements (TEs) are mobile genomic DNA seque

212 Transposable elements (TEs) are mobile units of DNA that

213 Transposable elements (TEs) are powerful motors of genom

214 Transposable elements (TEs) are repeated DNA sequences t

215 Transposable elements (TEs) are selfish genetic units th

216 Transposable elements (TEs) are silenced in germ cells b

217 Transposable elements (TEs) are uniquely equipped to dep

218 In many eukaryotic genomes, transposable elements (TEs) are widely distributed and o

219 Transposable elements (TEs) are widespread genomic paras

220 ting the expression of both coding genes and transposable elements (TEs) between hybrid sterile males

221 Recent studies have shown that transposable elements (TEs) can also mediate recurrent d

222 Transposable elements (TEs) can be found in virtually al

223 It is well documented that transposable elements (TEs) can regulate the expression

224 Genomic transposable elements (TEs) comprise nearly half of the

225 Transposable elements (TEs) constitute the most active,

226 Transposable elements (TEs) contribute to the large amou

227 s and Piwi-interacting RNAs (piRNAs) repress transposable elements (TEs) from mobilizing in gonadal c

228 Transposable elements (TEs) generate mutations and chrom

229 Transposable elements (TEs) have been shown to contain f

230 Transposable elements (TEs) have had a major influence o

231 its structure suggests a fundamental role of transposable elements (TEs) in adaptive evolution.

232 Studies of the population dynamics of transposable elements (TEs) in Drosophila melanogaster i

233 Small RNAs are used to silence transposable elements (TEs) in many eukaryotes, which us

234 n this study, we focused on the evolution of transposable elements (TEs) in relation to the genome si

235 ll noncoding RNAs that control expression of transposable elements (TEs) in the Drosophila germline.

236 Variation in the presence or absence of transposable elements (TEs) is a major source of genetic

237 In eukaryotes, aberrant expression of transposable elements (TEs) is detrimental to the host g

238 The mobilization of transposable elements (TEs) is suppressed by host genome

239 Transposable elements (TEs) make up a large proportion o

240 Transposable elements (TEs) may contribute to evolutiona

241 Transposable elements (TEs) occupy a large fraction of m

242 es account for 67.2% of the AtDt genome, and transposable elements (TEs) originating from Dt seem mor

243 Transposable elements (TEs) proliferate within the genom

244 Transposable elements (TEs) represent the single largest

245 The excision and reintegration of transposable elements (TEs) restructure their host genom

246 rt Interspersed Nuclear Elements (SINEs) are transposable elements (TEs) that amplify through a copy-

247 (piRNAs) protect the germ line by targeting transposable elements (TEs) through the base-pair comple

248 all RNAs, plays a major role in silencing of transposable elements (TEs) to maintain genome integrity

249 It is hypermethylated within transposable elements (TEs), accompanied by increased ab

250 ndogenous gene expression, controls invading transposable elements (TEs), and protects the cell again

251 recognition and transcriptional silencing of transposable elements (TEs), consistent with an 'arms ra

252 We map the evolutionary trajectories of transposable elements (TEs), developmental genes and sex

253 Newly evolved CREs are enriched in young transposable elements (TEs), including Long-Terminal-Rep

254 hroughout the entire seed, targets primarily transposable elements (TEs), is maintained during endore

255 Repetitive DNA, especially that due to transposable elements (TEs), makes up a large fraction o

256 hypomethylation of protein-coding genes and transposable elements (TEs), preferentially those adjace

257 titive DNA elements, repress mobilization of transposable elements (TEs), template or bridge DNA doub

258 e comprised of repetitive sequences, such as transposable elements (TEs), which have been implicated

259 These regions are often occupied by transposable elements (TEs), which make up between 20 an

260 ation, little is known about their effect on transposable elements (TEs), which make up nearly half o

261 Half the human genome is made of transposable elements (TEs), whose ongoing activity cont

262 ensation and transcriptional reactivation of transposable elements (TEs).

263 alian genomes and are frequently enriched in transposable elements (TEs).

264 rity of HTs reported so far are transfers of transposable elements (TEs).

265 ess parasitic mobile sequences of DNA called transposable elements (TEs).

266 and transcriptional gene silencing (TGS) of transposable elements (TEs).

267 ads to risk of transcriptional activation of transposable elements (TEs).

268 s central to controlling the mobilization of transposable elements (TEs).

269 f parental alleles, particularly at proximal transposable elements (TEs).

270 utilizes the termini of two separate, nearby transposable elements (TEs).

271 elanogaster, where it acts to silence active transposable elements (TEs).

272 ghlighting the diversity and distribution of transposable elements (TEs).

273 mportant role in the regulation of genes and transposable elements (TEs); however, the role of DNA me

274 The maize genome has a high number of transposable elements (TEs; almost 85%), some of which s

275 mid north-facing slope carried about 6% more transposable elements than those from the hot and dry so

276 INE-1 (long interspersed element 1, L1) is a transposable element that has extensively colonized the

277 Furthermore, we discovered a transposable element that resides immediately upstream o

278 Piwi in the germline increases expression of transposable elements that are targeted by piRNAs, where

279 L1 retrotransposons are an abundant class of transposable elements that pose a threat to genome stabi

280 e frequently associated with the presence of transposable elements that preferentially belong to heli

281 n, age, and diversity of the highly abundant transposable elements, the primary factor determining ge

282 n of genes or their regulatory elements, and transposable elements themselves can act as alternative

283 Classified as a type of non-autonomous DNA transposable elements, they play important roles in geno

284 A clusters resulted in lower activity of the transposable elements through DNA methylation in the hyb

285 egulation of genes derived from Mutator-like transposable elements, thus contributing to the evolutio

286 predominant plasmid (pKpQIL), and a specific transposable element (Tn4401, 10 kb).

287 establishes and maintains DNA methylation at transposable elements to ensure genome stability in plan

288 onents regulate precursor mRNA splicing of P-transposable element transcripts in vivo, leading to the

289 Intriguingly, most of the transposable element transcripts maintained a fragmented

290 s and use guide piRNAs to target and destroy transposable element transcripts.

291 influence of bidirectional transcription and transposable elements, two pervasive features of vertebr

292 By studying subgroups of transposable elements, we also found that non-CpG methyl

293 preferentially enriched on edges of silenced transposable elements, where Pol V transcribes into TEs.

294 the accumulation of toxic transcripts of Alu transposable elements, which activate the NLRP3 inflamma

295 The cells contain tens of transposable elements, which likely cause the unpreceden

296 mplex organization of interspersed genes and transposable elements, which necessitates frequent bound

297 The discovery that the mutation itself is a transposable element will stimulate further debate about

298 thers; the phasiRNAs are predicted to target transposable elements, with their peak abundance during

299 An intronic, transposable element within SMOC2 promotes the utilizati

300 that LTR/Gypsy and LTR/Copia were two major transposable elements within the intronic polyadenylatio