ライフサイエンスコーパス: transsulfuration

1 ynthesis of cysteine and glutathione through transsulfuration.

2 mediated increase in serine biosynthesis and transsulfuration.

3 mitment of methionine cycle intermediates to transsulfuration.

4 ete AMC of H. pylori in a process of reverse transsulfuration.

5 ry position between the methionine cycle and transsulfuration.

6 ry position between the methionine cycle and transsulfuration.

7 Thus, reverse transsulfuration alone, without any sulfur recycling rea

8 .1.22] catalyzes the first committed step of transsulfuration and is the enzyme deficient in classica

9 ine other than serving as an intermediate in transsulfuration and to date, the possible contribution

10 in homocysteine remethylation or methionine transsulfuration and transmethylation between the groups

11 e the kinetics of methionine and its rate of transsulfuration and transmethylation in healthy women w

12 , associated with slower rates of methionine transsulfuration and transmethylation or homocysteine re

13 regulates the flux through remethylation and transsulfuration, and glycine N-methyltransferase regula

14 ethionine flux, its transmethylation and its transsulfuration, and homocysteine remethylation in chil

15 ering its flux through the transmethylation, transsulfuration, and transamination metabolic pathways.

16 betaine homocysteine methyl transferase and transsulfuration catalyzed by cystathionine beta-synthas

17 e kynurenine pathway, one-carbon metabolism, transsulfuration (cystathionine), and glycine decarboxyl

18 n humans is associated with a higher rate of transsulfuration early in gestation and a higher rate of

19 rt to a 38% increase in the abundance of the transsulfuration enzyme cystathionine beta-synthase; tre

20 euromodulator that can be synthesized by the transsulfuration enzymes cystathionine beta-synthase (CB

21 r than Cys-SSH is the primary product of the transsulfuration enzymes with CSE being the dominant pro

22 biogenesis of H(2)S involves the cytoplasmic transsulfuration enzymes, cystathionine beta-synthase an

23 iol and S(0), thus providing a mechanism for transsulfuration in the sulfane sulfur pool.

24 ve plasma concentrations of transmethylation/transsulfuration metabolites and glutathione redox statu

25 35S-methionine demonstrating that functional transsulfuration occurs in mammary cells.

26 The fractional rate and total rate of transsulfuration of methionine was significantly (P < 0.

27 etic or nutrient-related disturbances in the transsulfuration or remethylation pathways for homocyste

28 SAA) restriction increased expression of the transsulfuration pathway (TSP) enzyme cystathionine gamm

29 The transsulfuration pathway (TSP) is a highly conserved mec

30 mocysteine (SAH) is product of methionine in transsulfuration pathway and a potent competitive inhibi

31 es of the methionine cycle regulate both the transsulfuration pathway and As methylation; c) GSH serv

32 catalyzes the first irreversible step in the transsulfuration pathway and commits the toxic metabolit

33 study establishes the presence of an intact transsulfuration pathway and demonstrates its contributi

34 r cysteine and glutathione synthesis via the transsulfuration pathway as a defense against oxidative

35 thionine is formed as an intermediate of the transsulfuration pathway by the condensation of serine a

36 The redox sensitivity of the transsulfuration pathway can be rationalized as an autoc

37 The transsulfuration pathway converts homocysteine to cystei

38 We posit that regulation of the transsulfuration pathway during monocyte differentiation

39 The transsulfuration pathway enzymes can synthesize cysteine

40 the diversity of reactions catalyzed by the transsulfuration pathway enzymes, cystathionine beta-syn

41 of H(2)S in mammals and is catalyzed by the transsulfuration pathway enzymes, cystathionine beta-syn

42 capacity for Cys-SSH production by the human transsulfuration pathway enzymes, cystathionine beta-syn

43 he increase in homocysteine flux through the transsulfuration pathway exhibited a linear dose depende

44 The transsulfuration pathway generates cysteine, the limitin

45 ontrol design, we measured biomarkers of the transsulfuration pathway in a population-based sample of

46 the importance of the homocysteine-dependent transsulfuration pathway in the maintenance of the intra

47 cultured human astrocytes, flux through the transsulfuration pathway increased under oxidative stres

48 thionase, has led to the suggestion that the transsulfuration pathway is incomplete in the brain.

49 In conclusion, the diversion to the transsulfuration pathway means that this Met precursor i

50 and/or pathway inhibitors indicates that the transsulfuration pathway plays a significant role in pro

51 However, neither provision of the transsulfuration pathway product, cysteine, nor overexpr

52 l 5'-phosphate (PLP)-dependent enzyme of the transsulfuration pathway that condenses serine with homo

53 disease patients suggest impairments in the transsulfuration pathway that connects these metabolites

54 LP)-dependent enzyme, which functions in the transsulfuration pathway that converts homocysteine to c

55 CBS) catalyzes the first of two steps in the transsulfuration pathway that converts homocysteine to c

56 gical confounders the combined assessment of transsulfuration pathway thiols shows that glutamylcyste

57 e investigated combined associations between transsulfuration pathway thiols, including homocysteine,

58 Metabolites in the transmethylation/transsulfuration pathway were measured before and after

59 omarkers of oxidative stress involved in the transsulfuration pathway were significantly higher in wo

60 H was proposed as the primary product of the transsulfuration pathway with H2S representing a decompo

61 Blockade of the transsulfuration pathway with propargylglycine suppresse

62 several ways: a) GSH is synthesized via the transsulfuration pathway, and Cys is the rate-limiting s

63 stathionine beta-synthase, a key gene in the transsulfuration pathway, and various glutathione produc

64 Produced by the enzymes involved in the transsulfuration pathway, cystathionine beta-synthase (C

65 The transsulfuration pathway, through which homocysteine fro

66 tween the integrated stress response and the transsulfuration pathway, we used homocysteine (Hcy) as

67 ne beta-synthase are critical enzymes in the transsulfuration pathway, which also regulate cellular r

68 that HMTBA is preferentially diverted to the transsulfuration pathway, which gives antioxidant metabo

69 is the first and rate-limiting enzyme in the transsulfuration pathway, which is critical for the synt

70 ich is synthesized from homocysteine via the transsulfuration pathway.

71 thionine, in the first step of the bacterial transsulfuration pathway.

72 oint in the biosynthesis of cysteine via the transsulfuration pathway.

73 r cells is derived from homocysteine via the transsulfuration pathway.

74 lites in the methionine transmethylation and transsulfuration pathways in children diagnosed with aut

75 nsamination, and not the transmethylation or transsulfuration pathways, contributed to methionine-ind

76 ino acid intermediate in the methylation and transsulfuration pathways.

77 cursor to methylation, aminopropylation, and transsulfuration pathways.

78 This transsulfuration reaction represents one of two major ce

79 rn of inhibition compared with the canonical transsulfuration reaction.

80 Because of its central role in transsulfuration, redox status, and H2S biogenesis, CBS

81 compounds modulating hCBS activity and thus transsulfuration, redox status, and H2S biogenesis.

82 (or betaine in an alternative reaction); and transsulfuration to cystathionine, which requires pyrido

83 ylated back to methionine or metabolized via transsulfuration to cystathionine.

84 reased folate and vitamin B12 levels and Hcy transsulfuration to cysteine.

85 accumulation of Hcy, which is channeled via transsulfuration to increase glutathione and enhance ars

86 re in which the flux of homocysteine through transsulfuration under normoxic and oxidative conditions

87 for independent modulation of the canonical transsulfuration versus H(2)S-generating reactions catal

88 smethylation via methionine synthase (MS) or transsulfuration via cystathionine beta-synthase (CBS).