ライフサイエンスコーパス: treatment strategy

1 ition of HIFs might represent a new powerful treatment strategy.

2 pe is the starting point for a comprehensive treatment strategy.

3 st savings compared to the pretransplant DAA treatment strategy.

4 Gene therapy is a promising treatment strategy.

5 ression from the intact allele is a rational treatment strategy.

6 usative fungi and institution of appropriate treatment strategy.

7 Inhibition of interleukin 1 is a promising treatment strategy.

8 relapse is critical for choosing the proper treatment strategy.

9 ing tool for the development of a new cancer treatment strategy.

10 differentiation arrest represent a powerful treatment strategy.

11 e basis for development of risk-adapted GVHD treatment strategies.

12 that could help inform development of future treatment strategies.

13 on how they have emerged as targets of novel treatment strategies.

14 may be exploited in the development of novel treatment strategies.

15 ies prognostic subgroups, and may help guide treatment strategies.

16 dualized diagnostic evaluations and tailored treatment strategies.

17 is a pressing need for newer, more effective treatment strategies.

18 HF but also can improve prognostication and treatment strategies.

19 ng antibiotic resistance requires innovative treatment strategies.

20 terization and translation into personalized treatment strategies.

21 a potentially important target for future HF treatment strategies.

22 OvCa) has motivated a search for alternative treatment strategies.

23 l to augment clinical trial design and guide treatment strategies.

24 anding of anxiety disorders and hence inform treatment strategies.

25 hed light on these processes and suggest new treatment strategies.

26 lure (HF) is critical to developing targeted treatment strategies.

27 could be a potential target for improving EC treatment strategies.

28 dheim-Chester disease (ECD) leading to novel treatment strategies.

29 impacts on both disease prevention and early treatment strategies.

30 g disease control and toxic effects of these treatment strategies.

31 ated AAV disease mechanisms may reveal novel treatment strategies.

32 disease relevant model in which to test new treatment strategies.

33 the long-term goal of improving TMJ disorder treatment strategies.

34 tes of cancer cells in response to different treatment strategies.

35 and optimization of therapeutic devices and treatment strategies.

36 CLL and offers opportunities for innovative treatment strategies.

37 tis delta in relation to different antiviral treatment strategies.

38 l to complement and/or combine with existing treatment strategies.

39 how excellent overall survival under current treatment strategies.

40 te of BACs in the environment and developing treatment strategies.

41 chnology that offers advantages over current treatment strategies.

42 ticity, but also provides novel insights for treatment strategies.

43 ronal circuits is needed to develop rational treatment strategies.

44 ion of compounds to be used in combinatorial treatment strategies.

45 d may inform improved disease prevention and treatment strategies.

46 nvestigate candidate therapeutic targets and treatment strategies.

47 on (HFpEF) is essential to tailor successful treatment strategies.

48 tcomes, predictive biomarkers, and potential treatment strategies.

49 ill be crucial for the development of better treatment strategies.

50 is crucial for the development of efficient treatment strategies.

51 s overall survival (OS) according to various treatment strategies.

52 -kingdom interaction and may impact clinical treatment strategies.

53 therapy remains to be established in current treatment strategies.

54 nered from genomic studies into personalized treatment strategies.

55 way for the development of novel therapeutic treatment strategies.

56 and to develop more effective prevention and treatment strategies.

57 ighly valuable for the design of anti-cancer treatment strategies.

58 the development of targeted surveillance and treatment strategies.

59 as well as potential future prophylactic and treatment strategies.

60 entions and develop alternative CNS-directed treatment strategies.

61 (2) novel molecular targets for antiplatelet treatment strategies.

62 ing may facilitate the development of future treatment strategies.

63 These studies will help identify novel treatment strategies.

64 e the relevance of these findings for future treatment strategies.

65 for development of improved prophylactic or treatment strategies.

66 y despite these medications necessitates new treatment strategies.

67 suitable for use in humans and management of treatment strategies.

68 PM and its potential advantage over current treatment strategies.

69 known, yet is key to optimising personalised treatment strategies.

70 heir unique properties when considering drug treatment strategies.

71 amics, which is necessary for more effective treatment strategies.

72 uate the cost-effectiveness of the following treatment strategies: (a) SBRT as initial treatment foll

73 te development of neurobiologically informed treatment strategies across neuropsychiatric conditions.

74 us infection in comparisons of the different treatment strategies against each other, including combi

75 ith its highly complex mutational landscape, treatment strategies against lung cancer have proved lar

76 network involving SNHG6-003 may be used as a treatment strategy against HCC.

77 Here, we examine if phages are an effective treatment strategy against this clonal group in murine m

78 velopment of new targets and pharmacological treatment strategies aiming to reduce CB sensory activit

79 oid malignancy usually refractory to current treatment strategies and associated with short overall s

80 iology, pathophysiology, diagnostic work-up, treatment strategies and follow-up was available.

81 acological manipulations, and facilitate new treatment strategies and strengthen translational models

82 Our aim was to assess the efficacy of treatment strategies and to identify factors that predic

83 nvasive coronary angiography showed CAD, the treatment strategy and completeness of revascularization

84 , and histologic transformation according to treatment strategy and explored prognostic factors for P

85 atheter ablation is an increasingly utilized treatment strategy and has evolved significantly over th

86 d with disease activity, define personalized treatment strategies, and generally inform clinical prac

87 Diagnostic procedures, treatment strategies, and their outcome were analyzed fo

88 Current treatment strategies are based on systemic administratio

89 lesional macrophages, new research areas and treatment strategies are beginning to emerge.

90 Although treatment strategies are currently based on modification

91 Two treatment strategies are currently used, a stepped appro

92 lergen avoidance, but a panoply of promising treatment strategies are in phase 2 and 3 studies, provi

93 given its natural sequence evolution, these treatment strategies are likely to impose additional sel

94 impairment, but effective disease-modifying treatment strategies are missing.

95 Current treatment strategies are mostly inadequate, leaving vict

96 ents with cancer, suggesting that additional treatment strategies are needed.

97 be a challenging disease to treat, thus new treatment strategies are needed.

98 Multiple treatment strategies are now available to patients whose

99 s disease, its molecular drivers and optimal treatment strategies are obscure.

100 mesenchymal tumors, better biomarker-driven treatment strategies are still needed.

101 n reliably measure the impact of a candidate treatment strategy are essential.

102 Results The mean costs of the denosumab treatment strategy are nine-fold higher than generic ZA

103 arization, and multivariable Cox models with treatment strategy as a 3-level time-varying covariate a

104 odulate reconsolidation, and suggest a novel treatment strategy, as reducing cue reactivity could lim

105 ized trials to develop personalized adaptive treatment strategies (ATSs)-longitudinal practice guidel

106 Combined treatment strategies based on magnetic nanoparticles (MN

107 thogenesis, which is now leading to emerging treatment strategies based on targeted therapy.

108 years and chronic graft-versus-host disease; treatment strategies based on these parameters may preve

109 In order to develop a treatment strategy based on potentiating mitochondrial f

110 diolabeled compounds are used to determine a treatment strategy by combining therapeutics and diagnos

111 The efficacy of novel treatment strategies cannot be established without bench

112 ypertensive therapies, and antihyperglycemic treatment strategies, cardiovascular complication rates

113 The proposed method combines a sample treatment strategy coming from metabolomics with liquid

114 he cost-effectiveness of a PCSK9i and statin treatment strategy compared with a statin alone strategy

115 nventional chemotherapy might be a promising treatment strategy decreasing relapse rates and enhancin

116 The primary endpoint was failure of the treatment strategy, defined as the absence of definite c

117 humans and animal models show that post hoc treatment strategies do not reliably prevent ID-induced

118 d treatment of the cause of iron deficiency, treatment strategies encompass prevention, including foo

119 After risk-adapted treatment strategies, especially in early-stage favorabl

120 No early postnatal treatment strategies exist to enhance neuroprotective po

121 Although promising treatment strategies exist, further research is needed t

122 Although initial treatment strategies focused on ablative therapy for thr

123 and neurological disorders could lead to new treatment strategies for a variety of sleep disturbances

124 n, which may ultimately lead to more optimal treatment strategies for anxiety- and stress-related dis

125 related signaling pathways would improve the treatment strategies for AR-positive breast cancer.

126 dy suggests that development of personalized treatment strategies for breast cancer patients could be

127 Abs targeting CD147 are being tested as new treatment strategies for cancer and autoimmune diseases.

128 Recent breakthroughs in novel immune-related treatment strategies for cancer have spurred interests i

129 thus present powerful and broadly applicable treatment strategies for cancer.

130 the insights needed for development of novel treatment strategies for cancer.

131 rogenesis may help in the elucidation of new treatment strategies for cartilage tissue regeneration.

132 ombination therapy are both common empirical treatment strategies for children hospitalized with pneu

133 sponse to omalizumab therapy and alternative treatment strategies for children with these risk factor

134 Current treatment strategies for claudication have limitations.

135 ceptors have now been developed as potential treatment strategies for common immune-mediated diseases

136 nd anti-fibrotic therapies could provide new treatment strategies for CTS.

137 needed in primary eye care as more effective treatment strategies for early AMD become available in t

138 is systematic review was to assess antenatal treatment strategies for FNAIT.

139 omic approach to the identification of novel treatment strategies for hematologic malignancies.

140 his pathway may provide novel prevention and treatment strategies for inflammatory bowel disease.

141 findings offer new opportunities to identify treatment strategies for inhibiting p17 release in the e

142 y suggest new avenues for the development of treatment strategies for leukemia.

143 nical need for the development of innovative treatment strategies for long-term repair and regenerati

144 Studies evaluating treatment strategies for management of T2MI are needed.

145 in vulnerability to THC SA may lead to novel treatment strategies for marijuana abuse.

146 PI are the most cost-effective, immune-based treatment strategies for metastatic melanoma.

147 lassification system might be used to select treatment strategies for patients with HCA.

148 dvantage of BRAF/MEK compared with all other treatment strategies for PFS.

149 molecular pathology, clinical features, and treatment strategies for some of the most common histioc

150 and presents suggestions for individualized treatment strategies for specific patient groups.

151 Treatment strategies for TBI are supportive, and the pat

152 Modern treatment strategies for the maintenance of allograft ac

153 for sex-specific research and individualized treatment strategies for the management of pain in men a

154 has stimulated considerable reexamination of treatment strategies for the management of retinopathy o

155 Unlike other treatment strategies for therapeutic revascularization t

156 Treatment strategies for these diseases have often targe

157 MS and diagnostic considerations and current treatment strategies for these patients.

158 ta may be a crucial step toward personalized treatment strategies for this disease.

159 nesis remains a major obstacle in developing treatment strategies for this disease.

160 needed to facilitate improved diagnosis and treatment strategies for this disease.

161 vealed new in-roads to develop detection and treatment strategies for this dreadful disease.

162 identification of key oncogenic drivers and treatment strategies for this lung cancer subtype.

163 on these advances, this article outlines how treatment strategies for thrombosis are evolving and des

164 that BDNF and/or KCC2 could represent novel treatment strategies for vestibular pathologies.

165 inate toxic Abeta42 oligomers as a promising treatment strategy for AD.

166 nt SHR and enhancing PFC activity could be a treatment strategy for ADHD.

167 stem cells (ASCs) is studied as a potential treatment strategy for AF defects.

168 Allergen immunotherapy (AIT) is an effective treatment strategy for allergic diseases and has been us

169 One proposed treatment strategy for Alzheimer's disease (AD) is the r

170 complement inhibition may prove a promising treatment strategy for bacterial sepsis.

171 PD-1 blockade and oHSV-1 may be an effective treatment strategy for childhood soft tissue sarcoma.

172 rovement of mucociliary clearance as a novel treatment strategy for children with allergen-induced as

173 at restoring functional beta cell mass as a treatment strategy for diabetes.

174 oligonucleotides (ASOs) could provide a new treatment strategy for disease.

175 repurposing mibefradil as a mechanism-based treatment strategy for GBM.

176 The current screening and treatment strategy for IDA fails to achieve this goal fo

177 NSCLC tumorigenesis, and reveals a potential treatment strategy for inhibiting the cancer transcripti

178 ining MEK and MDM2 inhibitors as a potential treatment strategy for KRAS mutant non-small cell lung c

179 osal epithelial cells (OMECs) is a promising treatment strategy for limbal stem cell deficiency.

180 and supports WIP1 inhibition as a potential treatment strategy for MB.

181 nt antiangiogenic therapy may be a promising treatment strategy for metastatic breast cancer.

182 Targeting the nerve-PNEC axis may be a valid treatment strategy for mucus overproduction in airway di

183 endothelial growth factor (VEGF) is a common treatment strategy for neovascular eye disease, a major

184 bination are needed to determine the optimal treatment strategy for patients with advanced NSCLC.

185 and induced stress conditions, indicating a treatment strategy for PD and other synucleinopathies.

186 Our results suggest an overall treatment strategy for re-establishing synaptic function

187 supports targeting of the KP as a potential treatment strategy for several major neurodegenerative d

188 targeted gene therapy represents a potential treatment strategy for STGD1 and other retinopathies ass

189 lementation of an ivermectin-based community treatment strategy for the elimination of onchocerciasis

190 oved anti-mucolytic agent, is a possible new treatment strategy for TTP, as it was demonstrated to re

191 enous administration of SCFAs as a potential treatment strategy for uveitis through the stabilization

192 Hence, we developed a prevention- and a treatment-strategy for overgeneralization.

193 e cells carry two X chromosomes, an emerging treatment strategy has been to reawaken the healthy alle

194 s analyses (CEAs) of hepatitis C virus (HCV) treatment strategies have become common, but few appear

195 HIV infection treatment strategies have historically defined effective

196 reased morbidity and mortality, yet, current treatment strategies have proven inadequate.

197 Targeted immune therapeutics and aggressive treatment strategies have substantially improved clinica

198 ho are in stable condition, the best initial treatment strategy--heart-rate control or rhythm control

199 A consequence of this treatment strategy, however, could be an increase in ser

200 -type natriuretic peptide (NT-proBNP)-guided treatment strategy improves clinical outcomes vs usual c

201 tics, or dosage; and the benefits of various treatment strategies in adults 40 years and older withou

202 However, the optimal assessment of new treatment strategies in humans is limited by currently a

203 Treg) represent a promising target for novel treatment strategies in patients with inflammatory/aller

204 sponse and therefore may inform personalized treatment strategies in patients with metastatic disease

205 To develop more efficient treatment strategies in patients with schizophrenia, a b

206 ective ART, and the efficacy of emerging HCV treatment strategies in persons with HIV/HCV coinfection

207 ortant when counseling patients and defining treatment strategies in pulmonary arterial hypertension

208 In particular, this measure may help target treatment strategies in specific hypertensive subpopulat

209 of-of-concept for direct BAX activation as a treatment strategy in AML.

210 terleukin 23 p19 that represents an evolving treatment strategy in chronic plaque psoriasis.

211 We thus demonstrate the first causal treatment strategy in hereditary spastic paraplegia.

212 ing of BCL-2 and MCL-1 could be an effective treatment strategy in myeloma.

213 CG) is emerging as an experimental secondary treatment strategy in systemic light chain amyloidosis (

214 t of a biomarker-based (personalized) cancer treatment strategy in the setting of phase 1 clinical tr

215 Current treatment strategies include beta-blockade, flecainide a

216 The other treatment strategies include locoregional therapies, rad

217 Treatment strategies included no active therapy in 47 (8

218 ic challenges will be resolved by a range of treatment strategies, including greater focus on specifi

219 ptake inhibitors remains a preferred initial treatment strategy, increasing evidence that supports th

220 ly centered on prognostic stratification and treatment strategies informed by acquired somatic mutati

221 In addition, potential treatment strategies involving fibrates, connexins, neur

222 Understanding critical limb ischemia and its treatment strategies is important for providing the best

223 e improved markedly, further optimization of treatment strategies is still needed given that 1 in 4 p

224 ex half-life are sufficient to explain which treatment strategy is most effective.

225 isk of relapse, although the benefit of this treatment strategy is unclear.

226 ducated decisions and design new combination treatment strategies, it is vital to learn more about co

227 functional outcome in schizophrenia, current treatment strategies largely fail to ameliorate these im

228 Therefore, better treatment strategies leading to higher disease control a

229 and reports of the extent to which different treatment strategies may influence long-term tooth loss

230 ion, advances in operative and non-operative treatment strategies may provide more effective ways to

231 At the same dose and with the same treatment strategies, MEAN was more efficacious in inhib

232 s and disease progression can be subtle, and treatment strategies must be tailored.

233 Compared with the first-line dacarbazine treatment strategy, NIVO followed by IPI produced an inc

234 event age-related bone loss suggests a novel treatment strategy not only for osteoporosis, but also f

235 y, clinical significance, and diagnostic and treatment strategies of human infection with these patho

236 tool to study mechanisms, interactions, and treatment strategies of kidney disease and atheroscleros

237 iofrequency catheter ablation has become the treatment strategy of choice for atrial tachyarrhythmias

238 The standard treatment strategy of mass drug administration with iver

239 argeting of BAFF has emerged as a successful treatment strategy of SLE.

240 l model of HIV dynamics, we demonstrate that treatment strategies offering modest but continual enhan

241 ferent methotrexate (MTX) and corticosteroid treatment strategies on neurocognitive functioning in ch

242 heory for comparing the effects of sustained treatment strategies, organizes analytic approaches, pro

243 edication used at lower doses with different treatment strategies, other medications in the same clas

244 tion toxicity constraint models and optimize treatment strategies over the space of tolerated schedul

245 Additionally, the treatment strategy prevented tubular brush border loss,

246 45 patients (51.7%) assigned to the standard treatment strategy (relative risk, 0.73; 95% CI, 0.56 to

247 An effective treatment strategy remains elusive.

248 An effective treatment strategy remains elusive.

249 In the HCC analysis, the pre-LT treatment strategy resulted in 11.48 per-patient quality

250 In the DCC analysis, the pre-LT treatment strategy resulted in 9.27 per-patient quality-

251 Although both treatment strategies seem to benefit the patients, the a

252 Therefore, alternate local treatment strategies should be considered for older, lum

253 atment options are available, but first-line treatment strategies should be optimized to efficiently

254 untries in the Asia-Pacific region, and thus treatment strategy should be adapted relative to country

255 nfirmed, has implications for developing new treatment strategies such as reducing the dopamine synth

256 ary role for amyloid-in Alzheimer's disease, treatment strategies targeted at reducing amyloid-have f

257 eating potential for improved prevention and treatment strategies targeted to those at risk.

258 s provide a strong rationale for combination treatment strategies targeting IL-17A for this subgroup

259 New treatment strategies targeting other neurotransmitter de

260 feedback loop is a more robust and effective treatment strategy than inhibiting other regulations, an

261 ic, pre-emptive, and sometimes non-intuitive treatment strategies that can better control tumors in r

262 ng patients, as well as for evaluating novel treatment strategies that could potentially prevent tran

263 results provide insight into prevention and treatment strategies that may be used to extend the wind

264 calized prostate cancer have to decide among treatment strategies that may differ in their likelihood

265 be targeted is crucial in devising effective treatment strategies that will benefit specific cancer p

266 notypically and suggest a phenotype-targeted treatment strategy that adapts to cancer as it evolves.

267 We considered two treatment strategies: the Constant Effort strategy, in w

268 cation of atmospheric plasma jets as medical treatment strategies, there has been comparatively littl

269 s a prerequisite for the design of effective treatment strategies to achieve HIV cure.

270 These results advocate for new treatment strategies to combat the long-term and extreme

271 lighting the need for the development of new treatment strategies to combat this disease agent.

272 entation of dynamic molecular monitoring and treatment strategies to improve cancer control.

273 et for anti-inflammatory or pro-dopaminergic treatment strategies to improve motivational and motor d

274 been linked to these phenotypes, but optimal treatment strategies to overcome chemotherapeutic resist

275 ce that LDR is a promising option for future treatment strategies to prevent cancer metastasis in bre

276 ld be a focus in future research to optimize treatment strategies to reduce a negative impact on the

277 Present treatment strategies to stratify exacerbation risk in pa

278 ing novel pharmacological and interventional treatment strategies to treat these disorders.

279 wnstream of the KRAS protein as an alternate treatment strategy to slow cancer growth and prolong sur

280 miology, assessment, therapeutic agents, and treatment strategies together with unmet needs of patien

281 The pretransplant DAA treatment strategy trended towards cost-effectiveness as

282 ML have otherwise largely relied on adopting treatment strategies used for MDS and MPN.

283 hanges in the panoply of respiratory support treatment strategies used within neonatal units.

284 In some cases, the best computed treatment strategy used unconventional therapy switching

285 In particular, several treatment strategies using acids and solvents are integr

286 Here, we developed a treatment strategy using an injectable system with photo

287 ients (38.1%) assigned to the individualized treatment strategy vs 75 of 145 patients (51.7%) assigne

288 of men with localized prostate cancer, each treatment strategy was associated with distinct patterns

289 Under base case conditions, the deferred DAA treatment strategy was found to be the "dominant" strate

290 As such, the pre-LT treatment strategy was found to be the most cost-effecti

291 No treatment strategy was found to confer a higher risk of

292 detailed clinical vignettes wherein the best treatment strategy was uncertain.

293 To facilitate the development of mGluR5 treatment strategies, we tested the therapeutic utility

294 For each treatment strategy, we calculated the total cost and num

295 involving 6662 patients assigned to 1 of 10 treatment strategies were included.

296 Initial treatment strategies were vitreous tap and intravitreal

297 nderlines the critical need to explore novel treatment strategies, which could postpone or prevent th

298 as improved substantially as a result of new treatment strategies with non-anthracycline-based chemot

299 Here, we describe a long-term treatment strategy with the selective endothelin-A recep

300 iew current and potential future control and treatment strategies, with a focus on novel antimicrobia