ライフサイエンスコーパス: trefoil

1 oncentrations: the beta-hairpin interface of trefoils 1 and 2 and the H2a-H2 helical region.

2 The site in beta-trefoil-1 is located near the binding site of the fascin

3 ed by pseudo-2-fold symmetry to that in beta-trefoil-1.

4 largest of which is the D(3)(h)()-symmetric "trefoil" 2 and is composed of three [18]annulenes fused

5 The site in beta-trefoil-3 is related by pseudo-2-fold symmetry to that i

6 d that the topological landscape of the beta-trefoils allows for the population of diverse, geometric

7 s, propellers, 2-solenoid, super-roll, clam, trefoil and box are not widely distributed and were prob

8 components in both PK and DSAEK groups were trefoil and coma from the anterior corneal surface (P <

9 olecular topologies (including catenanes and trefoil and pentafoil knots).

10 CC harbors two lectin-like domains: the beta-Trefoil and the beta-Prism domains; however, precise con

11 sitions in the pseudo-symmetric units of the trefoil, and are juxtaposed to one another in conformati

12 hanges in astigmatism, spherical aberration, trefoil, and coma with accommodation, which must arise f

13 r generally poor thermal stability, the beta-trefoil architecture appears capable of substantial ther

14 iary structure symmetry inherent in the beta-trefoil architecture.

15 a homotrimer, producing a thermostable beta-trefoil architecture.

16 linear DNAs demonstrates that the two chiral trefoils are produced in equal amounts, suggesting that

17 led lone-pair Sn states involved in in-plane trefoil aromatic interactions.

18 The "trefoil" aromaticity, previously postulated for aromatic

19 or (EGF-R) activation was also necessary for trefoil auto- and cross-induction, and both spasmolytic

20 e, the negative-noded and positive-noded DNA trefoils can be resolved by gel electrophoresis.

21 ations and surface features of the family of trefoil cell motility factors (porcine SP, pS2, and hITF

22 tailed structural comparisons with the other trefoil cell motility factors.

23 DNA might be detectable from an analysis of trefoil chirality.

24 an square of total higher order aberrations, trefoil, coma, tetrafoil, secondary astigmatism, and sph

25 P > 0.05), but the WF-guided group had less trefoil compared with the WF-optimized group (0.14 +/- 0

26 e N- and C-terminal regions outside the beta-trefoil core in FGF9 are ordered and involved in the for

27 The FHF1b beta-trefoil core is remarkably similar to that of classical

28 he betaC'-betaE loop interacts with the beta-trefoil core region of FGF1, in the FGF1-FGFR3c structur

29 s dependent on sequences outside of the beta-trefoil core.

30 structure of the TFF3 monomer and with other trefoil dimer structures (TFF1 and TFF2).

31 transcription factors, but a surprising beta-trefoil domain (BTD) is inserted between them.

32 RAM region of the Notch receptor to the beta-trefoil domain (BTD) of CSL.

33 n motifs, we expressed the isolated VVH beta-trefoil domain and used glycan-chip screening to identif

34 intermolecular disulfide bonds via an extra-trefoil domain cysteine residue and are present in vivo

35 The core of the trefoil domain in hITF consists of a two-stranded antipa

36 gnificant structural differences between the trefoil domain in the monomer and dimer TFF3 are in the

37 However, neither an intact trefoil domain nor dimerization was required to promote

38 RAM domain of Notch interacts with the beta trefoil domain of CSL; however, the C-terminal domain of

39 nt in the ZP domain and 6 are present in the trefoil domain of VEalpha and VEbeta.

40 Each contains one trefoil domain that is characterized by several conserve

41 s in loop regions within the C-terminal beta-trefoil domain which showed greatly reduced ganglioside

42 egions to a key interaction domain (the beta trefoil domain, or BTD) of human CSL.

43 de (SP, 106 residues) form a small family of trefoil domain-containing mammalian cell motility factor

44 VEalpha and VEbeta also have a trefoil domain.

45 vities are housed within the C-terminal beta-trefoil domain.

46 egions of high sequence conservation in beta-trefoil domains 1 and 3.

47 s compared with the TFF1 dimer where the two trefoil domains are connected by a flexible region with

48 h N-terminal mART and C-terminal tandem beta-trefoil domains associate to form an overall architectur

49 triplicated repeats in each of the four beta-trefoil domains of fascins are significantly similar in

50 eals a novel arrangement of four tandem beta-trefoil domains that form a bi-lobed structure with appr

51 been proposed to form the functional site of trefoil domains.

52 Fascin consists of four beta-trefoil domains.

53 f strongly induced after mucosal damage, the trefoil/EGF-R relationship may be pivotal in the generat

54 The gene coding for human intestinal trefoil factor (hITF), a recently described cellular mot

55 e factors revealed that the human intestinal trefoil factor (ITF) gene promoter bears a previously un

56 ' flanking sequence of the murine intestinal trefoil factor (ITF) gene was found to confer goblet cel

57 Intestinal trefoil factor (ITF) is an essential regulator of coloni

58 Intestinal trefoil factor (ITF) is selectively expressed in goblet

59 Intestinal trefoil factor (ITF) is selectively expressed in intesti

60 GF-I, interleukin (IL)-1beta, and intestinal trefoil factor (ITF) messenger RNAs (mRNAs) were measure

61 out inducing marker genes such as intestinal trefoil factor (ITF) or myo-inositol-1-phosphate synthas

62 The trefoil peptide intestinal trefoil factor (ITF) plays a critical role in the protec

63 Intestinal trefoil factor (ITF) promotes epithelial cell migration

64 molytic polypeptide (rHSP) or rat intestinal trefoil factor (ITF) were administered at different dose

65 The gene encoding intestinal trefoil factor (ITF), a protein secreted throughout the

66 ially ameliorate injury including intestinal trefoil factor (ITF), a small protease-resistant peptide

67 Intestinal trefoil factor (ITF), a small, compact protease-resistan

68 in the intestine-specific peptide intestinal trefoil factor (ITF), in which colonic restitution is le

69 n of the goblet cell gene product intestinal trefoil factor (ITF).

70 The secreted proteins intestinal trefoil factor (ITF, 59 residues), pS2 (60 residues), an

71 The intestinal trefoil factor (ITF/TFF3) protects intestinal epithelia

72 (81%) of the gene encoding murine intestinal trefoil factor (mITF) and its whole genomic organization

73 and efficacy of recombinant human intestinal trefoil factor (rhITF) administered as topical oral spra

74 eceptor (TLR) 2 and modulation of GC-derived trefoil factor (TFF) 3 are functionally linked in the in

75 Trefoil factor (TFF) peptides are pivotal for gastric re

76 Trefoil factor (TFF) peptides, with a 40-amino acid moti

77 ed in malignant brain tumors (DMBT1) and the trefoil factor (TFF) proteins have all been proposed to

78 d for Ki67, ER, progesterone receptor (PgR), trefoil factor 1 (PS2), HER1 (epidermal growth factor re

79 repress estrogen-stimulated transcription of trefoil factor 1 (TFF1 or pS2) by stalling RNA polymeras

80 ), comprising the regulatory elements of the trefoil factor 1 (Tff1) gene and the tamoxifen-inducible

81 Trefoil factor 1 (TFF1) is a secreted protein involved i

82 Trefoil factor 1 (TFF1) is a tumor suppressor gene that

83 Epigenetic alterations of the trefoil factor 1 (TFF1) tumor suppressor gene were evalu

84 and negatively associated with expression of trefoil factor 1 (TFF1).

85 -mediated induction of many genes, including trefoil factor 1 and keratin 14, were inhibited by great

86 n of the estrogen-regulated proteins PgR and trefoil factor 1, regardless of HER1/2 status (P < 0.000

87 erstood, this study investigated the role of trefoil factor 2 (TFF2), a well-established regulator of

88 previously identified hypomethylated genes (trefoil factor 2 and lipocalin 2) between pancreatic and

89 se tags corresponded to genes (lipocalin and trefoil factor 2) previously shown to be overexpressed i

90 his study, we demonstrate in mice that TFF2 (trefoil factor 2), an epithelial cell-derived repair mol

91 of cells that coexpressed intrinsic factor, trefoil factor 2, and Griffonia (Bandeiraea) simplicifol

92 The capacities of urinary trefoil factor 3 (TFF3) and urinary albumin to detect ac

93 munohistochemical staining for the biomarker Trefoil Factor 3 (TFF3), could be used to identify patie

94 x10(-16); MAF=0.22) in LRP2 (associated with trefoil factor 3 [TFF3]), and rs11048230 (P=4.77x10(-8);

95 a14) and masculine (cytochrome P450 4a12 and trefoil factor 3) genes, as well gender-neutral (H19 fet

96 gelatinase-associated lipocalin, cystatin C, trefoil factor 3, tissue inhibitor of metalloproteinase

97 probably because of the higher expression of trefoil factor 3, Toll-interacting protein, and zonula o

98 ion (cyclooxygenase-2 [COX-2] and intestinal trefoil factor [ITF]), and prostaglandin E2 (PGE2) level

99 ecreased apoptosis, and decreased intestinal trefoil factor expression in the mucosa of both the smal

100 observed robust regulation of the secretory trefoil factor family (TFF) members, including a causal

101 n IPMTs corresponded to three members of the trefoil factor family (TFF1, TFF2, and TFF3).

102 Trefoil factor family 2 (TFF2) is up-regulated in Helico

103 The secreted trefoil factor family 2 (TFF2) protein contributes to th

104 neck cells located below the isthmus express trefoil factor family 2 (TFF2) protein, TFF2 messenger R

105 Trefoil factor family 2 (TFF2), also known as spasmolyti

106 cursor compartment for IPMNs and the role of Trefoil factor family 2 (TFF2)-a protein expressed by PD

107 e rapid emergence of spasmolytic polypeptide/trefoil factor family 2 (TFF2)-expressing metaplasia (SP

108 We have described a trefoil factor family 2 (TFF2; spasmolytic polypeptide)

109 Trefoil factor family 2/spasmolytic polypeptide and intr

110 Microarray analysis identified trefoil factor family 3 (TFF3) as a gene expressed in bi

111 gene that encodes a peptide belonging to the trefoil factor family of protease-resistant peptides.

112 the first demonstration that a member of the trefoil factor family of proteins is bound covalently to

113 Trefoil factor family-1 (TFF1) is a key gastric tumor-su

114 nknown protein that we have called TFIZ1 for trefoil factor interactions(z) 1.

115 The trefoil factor peptides are a family of small highly con

116 Immunohistochemical analysis of trefoil factor TFF1, 2 and 3 showed that TFF1 and 3 loca

117 -defensins Defa24 and Defa-rs1) and colonic (trefoil factor Tff2) mucus barrier.

118 al control of GalNAc transfer by single TFF (Trefoil factor) domains as high stringency determinants.

119 Intestinal trefoil factor, an intestinal peptide that mediates anti

120 tinct members of the family (pS2, intestinal trefoil factor, and spasmolytic polypeptide) are produce

121 nes (multidrug resistance gene-1, intestinal trefoil factor, CD73), resulting in attenuated loss of b

122 other surface molecules, such as intestinal trefoil factor, help to maintain the structural integrit

123 Trefoil factor-1 (Tff1) expression is remarkably down-re

124 he potential for rapid up-regulation of this trefoil factor.

125 ed by expression and staining for intestinal trefoil factor.

126 he genes (claudin4, lipocalin2, 14-3-3sigma, trefoil factor2, S100A4, mesothelin, and prostate stem c

127 In the intestinal mucosa trefoil factors (TFF) and mucins (Muc) - primarily produ

128 Trefoil factors (TFFs) are secreted molecules that are i

129 forming growth factor, melatonin, serotonin, trefoil factors and H2S all enhance mucosal barrier func

130 Mucins, growth factors, and trefoil factors are involved in accelerating gastric inj

131 Although trefoil factors have been shown to activate signaling pa

132 hanisms in ulcer healing, the interaction of trefoil factors with the mucus gel, the interaction of g

133 The trefoil factors, a family of proteins abundantly express

134 Epithelial cells secrete trefoil factors, heat shock proteins, and secretory leuk

135 rget genes upregulated by GATA-4 and -5, the trefoil factors, inhibinalpha, and disabled-2 (Dab2) are

136 talloproteinases, heat-inducible factors and trefoil factors, protective functions of submucosal mono

137 ts indicate that the global fold of the beta-trefoil family determines the energy landscape but that

138 Trefoil family factor 2 (TFF2), also known as spasmolyti

139 other proteins of unknown function, are beta-trefoil family homologues.

140 spasmolytic polypeptide, is a member of the trefoil family of peptides and is expressed primarily in

141 can potentially be exploited for other beta-trefoil family proteins in the IL-1 and FGF families.

142 eta (IL-1beta) is a cytokine within the beta-trefoil family.

143 s of the cytolytic domain and contain a beta-trefoil fold and a beta-prism fold.

144 Complex folds like the beta-trefoil fold and functional loops like the beta-bulge of

145 lop designer cytokine activity into the beta-trefoil fold and may be of general use in regulation of

146 a single ricin B lectin domain with its beta-trefoil fold and one carbohydrate-binding site.

147 This hints at how the beta-trefoil fold arose from the duplication of an ancestral

148 The beta-trefoil fold characteristic of native IL-1ra was preserv

149 The FHF1b core domain assumes a beta-trefoil fold consisting of 12 antiparallel beta strands

150 tly identified FGF-2 as a member of the beta-trefoil fold family.

151 the design of a foldable, thermostable beta-trefoil fold is possible.

152 interactions within the pseudosymmetric beta-trefoil fold of IL-1beta highlight the backbone water in

153 The regulatory role of the beta-trefoil fold of ppGalNAc-Ts in enzymatic activity of gly

154 FGF4 adopts a beta-trefoil fold similar to other FGFs.

155 FGF9 adopts a beta-trefoil fold similar to other FGFs.

156 the extrinsic effect of lectin domains (beta-trefoil fold) of polypeptide GalNAc-transferases (ppGalN

157 n architecture (the threefold symmetric beta-trefoil fold).

158 phobic core residues that stabilize the beta-trefoil fold, as well as interfacial residues that are l

159 viously revealed that they both adopt a beta-trefoil fold, similar to those found in Kunitz soybean t

160 tor-1, a member of the 3-fold symmetric beta-trefoil fold, was subjected to a series of symmetric con

161 interleukin-1beta (IL-1beta), adopts a beta-trefoil fold.

162 toxin complex consists of a reoccurring beta-trefoil fold.

163 e interactions essential for maintaining the trefoil fold.

164 ructure revealed that the protein has a beta-trefoil fold.

165 llowed by closure of the barrel in this beta-trefoil fold.

166 rands, distinguishing cospin from other beta-trefoil-fold serine protease inhibitors in which beta4-b

167 aberration for Kelman Duet (P = .753) and in trefoil for Acrysoft (P = .059).

168 the anterior corneal surface (P < 0.05) and trefoil from the posterior corneal surface (P < 0.05).

169 he murine genome, a region syntenic with the trefoil gene cluster on human chromosome 21q22.3.

170 The trefoil gene family of mucus cell-secreted proteins is a

171 Transcription of trefoil genes is induced during mucosal repair, but the

172 ed, showed reduced expression of the gastric trefoil genes SP and pS2, suggesting that trefoil peptid

173 n (HSQC) NMR spectra confirmed that the beta-trefoil global fold was largely intact under these three

174 within the immunodominant H chain as a beta-trefoil (Hcbetatre) structure; we hypothesize that induc

175 uces more negative-noded than positive-noded trefoils, indicating an asymmetry in the interaction bet

176 The inversion product is a trefoil, its unique topology being conferred by the exte

177 f this tail suggests that ClpXP tightens the trefoil knot against GFP, which prevents GFP unfolding.

178 These and the earlier discovery of a trefoil knot also suggest that the number of rigid compo

179 ein AFV3-109 is transformed into a tightened trefoil knot by applied pulling force.

180 Despite possessing the trefoil knot characteristic of SPOUT enzymes, Trm10 does

181 strategy for the preparation of a molecular trefoil knot from a flexible bipyridine oligomer and a z

182 ere the near-quantitative self-assembly of a trefoil knot from a naphthalenediimide-based aqueous dis

183 e stereoselective synthesis of a left-handed trefoil knot from a tris(2,6-pyridinedicarboxamide) olig

184 losing olefin metathesis to form a molecular trefoil knot in 58% yield.

185 etathesis affords a single enantiomer of the trefoil knot in 90% yield.

186 lexities involved in the formation of a deep trefoil knot in a polypeptide backbone.

187 n the SpoU family of MTases, contains a deep trefoil knot in its C-terminal region.

188 to show that the free energy cost to form a trefoil knot in the denatured state of a polypeptide cha

189 slipknot can be transformed into a tightened trefoil knot involving approximately 13 amino acid resid

190 ut the use of only (R,R)-1 leads solely to a trefoil knot of Lambda-handedness, whereas (S,S)-1 forms

191 ional methods to investigate the effect of a trefoil knot on the breaking strength of a polymer stran

192 rial TrmD has the unusual class IV fold of a trefoil knot structure.

193 pocket, and reveals an unusually formed deep trefoil knot that stabilizes this region.

194 tein Data Bank, a previously unreported deep trefoil knot was found in acetylornithine transcarbamyla

195 The first synthetic molecular trefoil knot was prepared in the late 1980s.

196 -handedness, whereas (S,S)-1 forms the Delta-trefoil knot with complete stereoselectivity.

197 different topological states (a circle and a trefoil knot) when ligated into a cyclic molecule.

198 the AdoMet-binding pocket, formed by a deep trefoil knot, contains a bound phosphate molecule, which

199 bute to an early and a late formation of the trefoil knot, respectively.

200 kbone polypeptide chain folds to form a deep trefoil knot.

201 ly generates the wholly organic 81-atom-loop trefoil knot.

202 he metathesis product results in a molecular trefoil knot.

203 TrmD features a trefoil-knot active-site structure whereas Trm5 features

204 The specific production of (+) trefoil knots in the presence of condensin and a type II

205 embers of the alpha/beta-knot clan form deep trefoil knots in their native backbone structure, a topo

206 hesis to form topologically chiral molecular trefoil knots of single handedness.

207 roteins considered to be knotted form simple trefoil knots with one end of the chain extending throug

208 rom small-molecule building blocks have been trefoil knots, the first pentafoil knot was recently syn

209 structures and colloidal particles, such as trefoil knots, with 'frozen' orientational order of flak

210 strategy is reported for the production of a trefoil knotted polymer from a copper(I)-templated helic

211 ts, confirmed the formation of the resulting trefoil knotted polymer.

212 sm of knotting and folding for two bacterial trefoil-knotted methyltransferases.

213 Here, we characterized the effects of the trefoil-knotted protein MJ0366 from Methanocaldococcus j

214 argeting domain predicted to resemble a beta-trefoil lectin fold.

215 biaceae type 1 RIPs fused with a double beta trefoil lectin gene similar to the actual Cucurbitaceae

216 lover (Trifolium pratense L.), and birdsfoot trefoil (Lotus corniculatus L.).

217 Trefoil-mediated transcriptional regulation required act

218 nctional regions are not central to the beta-trefoil motif and cause slow folding.

219 ITF contains a unique three-looped trefoil motif formed by intrachain disulfide bonds among

220 The compact structure of the trefoil motif may be responsible for marked resistance o

221 Any alteration of the trefoil motif or truncation resulted in loss of protease

222 The unique three-loop structure of the trefoil motif, formed by intrachain disulfide bonds in a

223 of macromolecules indicates that the simple trefoil or 'overhand' knot is likely to be present in an

224 y favour the formation of constructs tied in trefoil or pentafoil, or even of more exotic torus knots

225 showed the lowest values at central zone for trefoil (P = .043) and tetrafoil (P = .002) in AC group.

226 ned unchanged (P = 0.07) while the change in trefoil (P = 0.047) postoperatively, was not clinically

227 The trefoil pancreatic spasmolytic polypeptide (PSP) was tes

228 lsewhere, is a member of the rapidly growing trefoil peptide family.

229 The trefoil peptide intestinal trefoil factor (ITF) plays a

230 The dimer contains two deep trefoil peptide knots and a peptide loop extending from

231 the pancreas, under control of the pS2 mouse trefoil peptide promoter.

232 -coated pits, suggesting that integration of trefoil peptide responses may occur after internalizatio

233 surface receptor has been directly linked to trefoil peptide signaling.

234 Gastrin-stimulated expression of the trefoil peptide TFF1 in mouse fundus and in the gastric

235 Trefoil peptide-2-deficient mice were more susceptible t

236 to block apoptosis correlated with a loss of trefoil peptide-induced transactivation of the EGF recep

237 Trefoil peptides are ectopically expressed adjacent to a

238 Trefoil peptides are expressed near endodermal ulceratio

239 al anti-inflammatory agents, confirming that trefoil peptides increased the barrier properties of the

240 Expression of trefoil peptides is closely related to that of mucin gly

241 ic trefoil genes SP and pS2, suggesting that trefoil peptides may individually regulate transcription

242 ines the effects of exogenously administered trefoil peptides on experimental injury in rats in vivo.

243 Topical trefoil peptides protect the gastric mucosa against etha

244 may be responsible for marked resistance of trefoil peptides to proteolytic digestion, enabling them

245 Trefoil peptides, a growing family of secretory molecule

246 nked to those encoding the other known human trefoil peptides, namely the breast cancer estrogen-indu

247 enerating bicarbonate, mucus, phospholipids, trefoil peptides, prostaglandins (PGs), and heat shock p

248 there have been striking findings regarding trefoil peptides, the protective effect of regulatory pe

249 d repair predominantly through production of trefoil peptides.

250 l cell line that does not express endogenous trefoil peptides.

251 s not associated with systemic absorption of trefoil peptides.

252 Analysis of the chirality of trefoils produced by cyclization of two linear DNAs demo

253 a are shared among other members of the beta-trefoil protein family, although clear differences can e

254 op 2/loop 3 regions, which suggest that each trefoil protein has a specific target or group of target

255 The beta-trefoil protein human fibroblast growth factor-1 (FGF-1)

256 These showed that the 6.67 kDa secreted trefoil protein is present as an approximately 25 kDa co

257 The human trefoil protein TFF1 is a small cysteine-rich secreted p

258 The trefoil protein TFF3 forms a homodimer (via a disulfide

259 The trefoil protein TFF3 stimulates invasion and angiogenesi

260 This process culminated in a beta-trefoil protein with exact 3-fold primary-structure symm

261 e accurately the folding pathway of the beta-trefoil protein, interleukin-1beta (IL-1beta).

262 cules and proteins (eg, the mucin-associated trefoil proteins and estrogens).

263 have explored the sequence space of all beta-trefoil proteins and have determined that the actin-bind

264 provide statistical evidence that these beta-trefoil proteins are all homologues, having arisen from

265 The human trefoil proteins TFF1 and TFF3 are expressed predominant

266 ns within the folded ensembles of other beta-trefoil proteins, such as IL-1beta and hFGF-1.

267 Unlike other beta-trefoil proteins, the triplicated repeats in each of the

268 gnition properties of Cys-MR with other beta-trefoil proteins.

269 ssary for this response, suggesting that the trefoil receptor or its signal transduction is GSH sensi

270 ared to 5 years, CDVA improved (P < .05) and trefoil reduced (P < .05).

271 o an approximately three-fold symmetric beta-trefoil shape resembling fibroblast growth factor.

272 Here, we characterize trefoil-shaped outer-sphere lanthanide chloride and nitr

273 synthesis and characterization of star- and trefoil-shaped polyethynyl aromatic structures, which re

274 The beta-trefoil structural family members IL-1beta, hisactophili

275 at might function either supporting the beta-trefoil structure or in the communication between both s

276 -1beta (IL-1beta) structural motif is a beta-trefoil super fold created by six two-stranded beta-hair

277 beta) is a cytokine and a member of the beta-trefoil superfamily of protein structures.

278 tion of apoA-I on the midsize disks and the "trefoil/tetrafoil" arrangement on spherical HDL.

279 The interaction between DMBT1(gp340) and trefoil TFFs proteins was investigated using an ELISA as

280 We show that supercoiling of a DNA trefoil, the simplest knotted ring, perturbs differently

281 lly important cytokine with a symmetric beta-trefoil topology, are characterized using optical spectr

282 lass of proteins characterized by their beta-trefoil topology.

283 Golden trefoils: Tris(alkyne)gold complex [(coct)(3)Au][SbF(6)]

284 the 5'-OH leaving group of the reaction by a trefoil turn in the RNA backbone.

285 forms, especially in the P1.1 helix and the trefoil turn in the single-stranded region connecting P4

286 that this local conformational change in the trefoil turn is kinetically coincidental with a previous

287 76) is stacked with other bases and that the trefoil turn is not formed.

288 By modifying G(76) of the trefoil turn of a synthetic trans-cleaving HDV ribozyme

289 these substrate analogues on the ribozyme's trefoil turn of the catalytic core.

290 Our results demonstrate that the trefoil turn of the HDV ribozyme catalytic core is in a

291 pair and the A-minor motif of the catalytic trefoil turn that depend on the identity of the N-1 base

292 cked and solvent-exposed as evidenced in the trefoil turn.

293 cultures of Lotus corniculatus (bird's foot trefoil) using genetic manipulation.

294 In gastric cell lines, the trefoils were shown to act in a manner suggestive of imm

295 versions of an extant protein fold (the beta-trefoil) were produced by top-down symmetric deconstruct

296 (bird's foot trefoil) were transformed with an antisense chalcone syn

297 Vertical trefoil (Z3(-3)) was the predominant higher-order aberra

298 tively were vertical coma (Z3(-1)), vertical trefoil (Z3(-3)), and secondary astigmatism (Z4(4)).