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2 detail: the highly effective inhibitor 1,3,5-tri-[5-(1-quinolinum)-pent-1-yn-1-yl]-benzene tribromide
3 tPyQB) and the less potent antagonist 1,3,5,-tri-{5-[1-(2-picolinium)]-pent-1-yn-1-yl}benzene tribrom
4 at the designed alpha-helical peptide family TRI [(Ac-G(LKALEEK)4G-CONH2)], containing single site su
5 ed for the regioselective synthesis of 1,3,5-tri- and 1,3,4,5-tetrasubstituted pyrazoles by the react
8 successive action of exo-peptidases (mainly, tri- and di-peptidylpeptidases, aminopeptidases and carb
11 thylation of chlorosilanes is reported using tri- and difluoromethyl sulfides, sulfoxides, and sulfon
12 nes using magnesium metal-mediated reductive tri- and difluoromethylation of chlorosilanes is reporte
13 and efficient method for the preparation of tri- and difluoromethylsilanes using magnesium metal-med
14 detected in both the presence and absence of tri- and dihydroxy bile salts in rats, WT mice, and CELK
16 both parental alleles had similar levels of tri- and dimethylated H3K4 within the Gsalpha first exon
17 n containing 2A), which is selective towards tri- and dimethylated histone H3 lysyl residues 9 and 36
18 lso called JARID1A or KDM5A) can demethylate tri- and dimethylated lysine 4 in histone H3, which are
20 g oxygenase JMJD2A specifically demethylates tri- and dimethylated lysine-9 and lysine-36 of histone
21 KDM4 subfamily of demethylases removes H3K9 tri- and dimethylation and contributes to the regulation
22 KDM4A is a histone demethylase that targets tri- and dimethylation marks on histone H3 lysines 9 and
24 Orf153 (ymfB) is a nonspecific nucleoside tri- and diphosphatase and atypically releases inorganic
26 ng stimulates self-association of NrdR, with tri- and diphosphates stimulating oligomerization more e
27 lyzes the phosphodiester bonds of nucleoside tri- and diphosphates, but not monophosphates, thus disp
28 pyrase, an enzyme that hydrolyzes nucleoside tri- and diphosphates, each normalized ischemic leukoseq
29 ase that hydrolyzes extracellular nucleoside tri- and diphosphates, has seven potential N-glycosylati
33 n the same way, suggesting binding modes for tri- and hexanucleotide-repeat RNAs in two neurodegenera
35 shed and are illustrated by the formation of tri- and pentablock and scarf architectures with cylinde
37 Methods have been developed to synthesize tri- and pentapeptide thioesters containing one or more
38 r carry out the total syntheses of heparosan tri- and pentasaccharides and heparin di-, tetra-, hexa-
39 have previously investigated the binding of tri- and pentasaccharides of N-glycan with a GlcNAc at t
41 optimized in order to generate arsanes from tri- and pentavalent inorganic arsenic species (iAs(III)
42 on of plasmids with loxP sites: a model with tri- and possibly multimeric co-integrates comprising th
45 4,4'-)-dicarbomethoxydibenzo-27-crown-9 with tri- and tetra-(ethyleneoxy) linkages transposed were sy
47 hown to be correlated with the expression of tri- and tetra-antennary beta1,6-N-acetylglucosamine (be
48 he high-pI fractions, nor were predominantly tri- and tetra-antennary glycans associated with low-pI
49 MALDI-MS data revealed several fucosylated tri- and tetra-antennary glycans which were significantl
50 reduced content and structural diversity of tri- and tetra-antennary N-glycans and of O-glycans, 2)
51 pecificity and activity of human FUT8 toward tri- and tetra-antennary N-glycans in the forms of glyco
54 ized acyl chains, phosphatidic acids (PAs)), tri- and tetra-galactosyldiacylglycerols (TrGDGs and TeG
55 s efficient preparation of hindered biaryls (tri- and tetra-ortho-substituted), functions effectively
56 played high activity in the hydrogenation of tri- and tetra-substituted alkenes with TON > 8000 for t
58 relative amount of biantennary glycan versus tri- and tetraantennary glycans was different at separat
60 iantennary glycans, N83 containing primarily tri- and tetraantennary glycans, and N247 containing exc
61 entified carry more biantennary glycans than tri- and tetraantennary glycans, and the relative amount
62 a decrease in the amount of highly branched tri- and tetraantennary N-glycans, whereas monoantennary
64 rtho PCBs [OR = 4.55 (95% CI: 1.48, 13.95)], tri- and tetrachloro PCBs [OR = 3.66 (95% CI: 1.37, -9.7
65 A computational analysis of the reaction of tri- and tetracoordinate boron azides R2BN3 (R = H, Me,
70 ased hepatic BA hydrophilicity by increasing tri- and tetrahydroxylated and decreasing the dihydroxyl
71 ed the ability of these proteins to generate tri- and tetraketide lactone products using N-acetylcyst
72 e potent inhibitors, monosulfated benzofuran tri- and tetrameric homologues of the parent designed di
74 to Plasmodium chitinases: the enzymes cleave tri- and tetramers of GlcNAc from penta- and hexameric o
79 t base-stacking interactions; analyses of 62 tri- and tetranucleotide repeat-containing genes associa
80 Two thousand nine hundred and thirty-one tri- and tetranucleotide short tandem repeat polymorphis
83 wall but not the wall of S. aureus contained tri- and tetrapeptide units, suggesting the presence of
85 recovered support was utilized to synthesize tri- and tetrapeptides that contain amino acids other th
87 he oxygen- and novel carbon-linked adenosine tri- and tetraphosphate analogues are stable from pH 3 t
90 re mono-, 20% di-, and approximately 1% were tri- and tetraphosphopeptides, and 78 novel phosphorylat
91 conciled this issue using a panel of minimal tri- and tetrasaccharide sequences of variable but well
92 text] Syntheses of fluorinated mucin core 2 tri- and tetrasaccharides modified at the C-3 or C-4 pos
93 urves were generated for a series of related tri- and tetrasaccharides to evaluate their relative eff
97 f terminal, geminal, disubstituted internal, tri- and tetrasubstituted alkenes using pinacolborane (H
101 ocess is the ability to directly couple di-, tri- and tetrasubstituted alkenyl cyanohydrin pronucleop
103 odology for the stereoselective synthesis of tri- and tetrasubstituted allylic amines based on Pd-cat
104 A selective and convenient synthesis of tri- and tetrasubstituted alpha,beta-unsaturated ketones
105 ntioselective syntheses of challenging alpha-tri- and tetrasubstituted alpha-amino acids including an
107 chemo- and stereoselective access to various tri- and tetrasubstituted conjugated alkenones and alken
108 vertheless, a diverse range of unsymmetrical tri- and tetrasubstituted cyclobutane structures can be
109 of these reactions which form unsymmetrical tri- and tetrasubstituted cyclobutanes through a heterod
110 roalkenes, giving access to the synthesis of tri- and tetrasubstituted double bonds in Rauhut-Currier
111 yl amides to form nonpropenyl disubstituted, tri- and tetrasubstituted enamides with excellent geomet
112 A Bronsted acid-catalyzed method to prepare tri- and tetrasubstituted furans efficiently from cycloi
115 lysis and proceeds using sterically hindered tri- and tetrasubstituted olefins to give products conta
116 uide, analogues were synthesized in both the tri- and tetrasubstituted pyrrolidine series by means of
117 the cascade reactions of naturally occurring tri- and tetrasubstituted tetraenes (in agreement with c
118 component synthesis of highly functionalized tri- and tetrasubstituted thiophenes has been reported i
119 electivity and syn-stereoselectivity to form tri- and tetrasubstituted vinylboronic esters from comme
120 0' interprotomer cross-links, including di-, tri- and tetrasulfide bonds, which allosterically inhibi
122 s are green and blue-green in color, contain tri- and tetrasulfonated moieties, compared to the disul
123 ses that convert these diphosphates into the tri- and tetraterpene precursors of sterols, hopanoids,
125 ding, the binding of a series of mono-, bi-, tri- and tetravalent carboxylate ligands to Ca(II) was e
127 (4)L(6) through self-assembly reactions with tri- and tetravalent metal ions such as Ga(III), Fe(III)
128 rentiate HPAEC peak fractions containing the tri- and tri'-antennary branching isomers and two tetraa
129 e salts (TAA), benzylamines (mono-, di-, and tri-), and illicit drugs (MA, MDEA, and haloperidol).
130 he addition of dialkylzincs and (E)-di-, (E)-tri-, and (Z)-disubstituted vinylzinc reagents to alpha-
131 lpha-casein sample, while 19 mono-, 8 di-, 4 tri-, and 3 tetraphosphopeptides were identified in the
133 R screening of a comprehensive panel of di-, tri-, and high-mannose oligosaccharides establish that h
135 nt and selective (>or=98%) syntheses of di-, tri-, and oligoenes containing regio- and stereodefined
136 train synthesizing cross-bridges with mono-, tri-, and pentaglycyl as well as tetraglycyl-monoseryl,
138 everal unique LOS glycoforms containing di-, tri-, and poly-N-acetyllactosamine repeats added to the
140 ional ensembles of unacetylated, mono-, di-, tri-, and tetra-acetylated H4 histone tails using Replic
141 can reach a tetra-anionic state, mono-, di-, tri-, and tetra-anionic complexes likely dominate as the
142 ble, for the first time, to prepare any bi-, tri-, and tetra-antennary asymmetric N-glycan from a sin
143 nt strategy for the rapid production of bi-, tri-, and tetra-antennary complex type N-glycans with an
144 t of fully galactosylated or sialylated bi-, tri-, and tetra-antennary N-glycans was largely equivale
145 are common building blocks, a family of di-, tri-, and tetra-histidine-catecholic adducts, that were
146 he Sir proteins to reconstituted mono-, di-, tri-, and tetra-nucleosomal chromatin templates and show
150 Et2N:BH3 (10) and representative mono-, di-, tri-, and tetra-substituted olefins were carried out at
152 ul chemoselectivity in the synthesis of di-, tri-, and tetraamines (62 examples) by use of Buchwald-H
156 alysis revealed 24 lactosamine species (bi-, tri-, and tetraantennary structures), with all branches
157 wenty-amino acid PSA fragments carrying di-, tri-, and tetrabranched complex-type glycans were prepar
159 ation intermediates and accumulation of bi-, tri-, and tetracyclic sesterterpenes, revealing the cycl
161 l alpha-D-mannopyranoside residues, and di-, tri-, and tetrameric analogs possessing terminal 3, 6-di
162 A series of three short oligomers (di-, tri-, and tetramers) of cis-2-(aminomethyl)cyclobutane c
163 All members of this library of mono-, di-, tri-, and tetramethyl-substituted derivatives were chara
164 Applications to four different sets of di-, tri-, and tetranucleotide loci from a number of human po
165 the repeat structure including abundant di-, tri-, and tetranucleotide microsatellite loci yielded ac
166 is model and use it to fit DNA data for di-, tri-, and tetranucleotide repeats in humans, mice, fruit
168 howed that the mutation rate differs in di-, tri-, and tetranucleotide repeats, how mutation rate dis
170 g SSRs composed of iterations of mono-, di-, tri-, and tetranucleotides are mostly restricted to host
172 imple sequences consisting of repeating di-, tri-, and tetranucleotides, which allow the maximum reso
174 ))-H bonds of N-terminal amino acids in di-, tri-, and tetrapeptides without installing a directing g
175 had a narrow substrate specificity with di-, tri-, and tetrapeptides, and it hydrolyzed only basic N-
177 chsticks" self-assemble into multipods (bi-, tri-, and tetrapods) of varying coordination number and
178 nditions, regioselective methylation of di-, tri-, and tetrasaccharide substrates proceeded in isolat
179 vels of elongation of fucose-O-Thr61 to di-, tri-, and tetrasaccharides, not previously observed in r
180 and molecular weight of asialo-, mono-, di-, tri-, and tetrasialotransferrin variants was obtained fr
182 ferences in isoelectric point (pI), the di-, tri-, and tetrasialotransferrins are separated and resol
183 nal transferrin variants within each of di-, tri-, and tetrasialotransferrins, differing in their mol
186 broad range of N-allyl amides to form Z-di-, tri-, and tetrasubstituted enamides with exceptional geo
188 ocess shows functional group tolerance; di-, tri-, and tetrasubstituted N-vinylazoles were obtained i
189 regioselective incorporation of mono-, di-, tri-, and tetrasubstituted olefins at the alpha-carbon o
190 nversion of structurally diverse mono-, di-, tri-, and tetrasubstituted olefins to N-H aziridines usi
192 the desired product, including isomeric di-, tri-, and tetrasubstituted species previously believed t
193 sts for the asymmetric hydrogenation of di-, tri-, and tetrasubstituted unfunctionalized alkenes.
194 quent MS(2) and MS(3) spectra of mono-, di-, tri-, and tetrasulfated KS oligosaccharides and sialylat
195 lorimetry (ITC) data for the binding of di-, tri-, and tetravalent carbohydrate analogues possessing
196 from our previous report for binding of di-, tri-, and tetravalent carbohydrate analogues possessing
197 ever, Hill plots for the binding of the di-, tri-, and tetravalent trimannoside analogues to both lec
199 8 for monomethylated lysine, and 84 for di-, tri-, and unmethylated lysine) have been effectively use
202 reveal a "trans-tail" regulation of H3-Lys-4 tri- but not dimethylation by H2B-Lys-123 ubiquitination
203 A-Ni(II)-Zn(II) inhibitor complexes bound to tri-, di- and monomethyl forms of H3K9 and the trimethyl
205 in fatty acid uptake, lipid droplet size, or tri-, di-, or monoacylglycerol levels when compared with
207 our peptide nomenclature, the prefixes di-, tri-, etc. refer to the number of amino acid residues in
209 und throughout the genome, di- (H3K4me2) and tri- (H3K4me3) methylated H3K4 are enriched at specific
210 tial histone H3 methylation (mono-, di-, and tri-) is still not understood, and the involvement of do
211 ed unique mono- (K16Ac), di- (K12Ac, K16Ac), tri- (K8Ac, K12Ac, K16Ac), and tetra-acetylated (K5Ac, K
215 rmed in eight individuals with CAS affecting tri- or bileaflet aortic valves revealed considerable ol
217 a its chromodomain, binds histone H3 peptide tri- or di-methylated at lysine 9 (H3K9me3/H3K9me2) in s
218 innate immune sensor RIG-I distinguishes 5' tri- or diphosphate containing viral double-stranded (ds
219 d primers produced products with 5'-terminal tri- or diphosphate groups, indicating that genuine unpr
220 pin ribozyme appears to take up at least one tri- or divalent cation or two monovalent cations upon l
222 utinin is a homotrimeric receptor, and thus, tri- or oligovalent ligands should have a high binding a
223 ed on 3,5-dihydroxybenzyl alcohol containing tri- or tetrafunctional chiral central cores and allyl e
225 their ability to promote selective ethylene tri- or tetramerization in combination with chromium.
228 ts do not contain any particular unique di-, tri- or tetranucleotide sequences, but are frequently co
229 tion mutations lacking either the C-terminal tri- or tetrapeptide exhibit apparent size increases of
232 process gave access to highly functionalized tri- or tetrasubstituted dihydropyranones featuring an u
235 ng different glycine branch lengths (penta-, tri-, or monoglycine), while PBP2a can only cross-link p
241 letions (genetic instabilities) of repeating tri-, tetra- and pentanucleotide repeating sequences ass
242 Macrocyclization of suitably functionalized tri-, tetra- and pentapeptides via Suzuki-Miyaura cross-
243 that the major N-glycans were monosialylated tri-, tetra-, and penta-antennary oligosaccharides conta
244 classical methods, giving a wide variety of tri-, tetra-, and penta-substituted pyridines in high, o
246 In this way, selectively substituted di-, tri-, tetra-, and pentachloro-BODIPYs 2-5 were prepared.
248 iana yielded fungal-type sesterterpenes with tri-, tetra-, and pentacyclic scaffolds, and notably (-)
249 is enzymatic synthesis yielded predominantly tri-, tetra-, and pentaglutamyl species for the [(3)H]fo
251 sulfane ring structure predominates, and the tri-, tetra-, hexa-, hepta-, and nonasulfanes were prese
252 that differ in the length of their peptides (tri-, tetra-, or pentapeptides with or without mono- or
253 nthesized having hydrophilic spacers of di-, tri-, tetra-, penta(ethylene glycol) and tri(propylene g
254 ns, all types of microsatellite (mono-, di-, tri-, tetra-, penta-, and hexanucleotide repeats) are fo
255 The separation of myo-inositol mono-, di-, tri-, tetra-, pentakis-, and hexakisphosphate (InsP1, In
256 the native epitope becomes larger across the tri-, tetra-, pentasaccharide series, entropy contributi
257 inhibition of PPE can be effected by simple tri-, tetra-and pentapeptides terminating in a carboxyli
260 and analyzed using GC-negative ion MS for 26 tri- to decabromodiphenyl ethers (BDEs), as well as othe
262 he 5' end of transcribed genes in a 5'-to-3' tri- to di- to monomethyl gradient and promotes associat
263 roximal tubules there was a greater ratio of tri- to dimethylated H3K4 of Gsalpha exon 1 in the more
264 abetic db/m mice) and increased the ratio of tri- to disulfated disaccharides in hepatic HSPGs (P < 0
266 h-resolution mass spectrometry to measure 10 tri- to heptabrominated diphenyl eithers in serum sample
267 the arithmetic mean serum concentrations of tri- to hexaBDEs were lower in NHANES 2007/08 than in 20
268 ion contributed to the body burden of mostly tri- to hexachlorobiphenyls and produced a distinct prof
271 ified highly polymorphic BES-SSRs containing tri- to hexanucleotides motifs and bringing together rel
272 cases significantly correlated (P < 0.05) to tri- to nona-BDE homologues, and the strength of the cor
273 leven standard oligosaccharides ranging from tri- to nonasaccharide (3'-sialyllactose, 6'-sialyllacto
274 ngeners of 2,3,7- and 2,3,7,8-Br-substituted tri- to octabromodibenzo-p-dioxins and -furans, and all
275 attached support has been used to synthesize tri- to octapeptides in 28 to 97% yields using only 1.2
276 ibrary of 31 free HMOs, ranging in size from tri- to octasaccharide, was screened against three human
277 entic oligosaccharide standards ranging from tri- to octasaccharides, and their identities were confi
278 ermodynamic data demonstrate that the native tri- to pentasaccharides have free energies of binding i
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