ライフサイエンスコーパス: triazine

1 f MNX (hexahydro-1-nitroso-3,5-dinitro-1,3,5-triazine).

2 DLLME-SFO) was developed for the analysis of triazines.

3 he different reactivities of the substituted triazines.

4 the triazine to provide imidazo[1,2-a][1,3,5]triazines.

5 he impact is of a magnitude to convert 1,2,3-triazine (1) and its modest cycloaddition scope into a h

6 um, and potassium salts of 2,4,6-trimethyl-s-triazine (1) with 2-halomethyl-4,6-dimethyl-s-triazine (

7 of 2-amino-4-cyanopyrroles (3a-e) with 1,3,5-triazines (1, 2) is reported.

8 4-triazol-5-ylm ethoxy)pyrazolo[1,5-d][1,2,4]triazine (13) has been identified as a functionally sele

9 heny l]-1H-pyrazol-4-yl}imidazo[5,1-f][1,2,4]triazine, [(18)F]PF-05270430 (5).

10 The selectively (15)N labeled azido-1,2,4-triazine 2*A and azidopyrimidine 4*A were synthesized by

11 riazine (1) with 2-halomethyl-4,6-dimethyl-s-triazine (2) (X = Cl, Br) in glyme have been studied and

12 )(TATB)(2), where TATB represents 4,4',4''-s-triazine-2,4,6-triyl-tribenzoate with a formula of C(24)

13 4-(N-phenylanilino)-6-pyrrolidin-1-yl-1,3,5-triazine-2-carbonitrile (CP243522), showed a K(i) of 21

14 m, 6-hydroxy-2-(naphthalen-1-ylmethyl)-1,2,4-triazine-3,5(2H,4H)-dione 11h was found to be selective

15 A series of 2-substituted 6-hydroxy-1,2,4-triazine-3,5(2H,4H)-dione derivatives were synthesized a

16 The 6-hydroxy-1,2,4-triazine-3,5(2H,4H)-dione pharmacophore appears metaboli

17 yl)piperazin-1-yl]butyl}-4- methyl-2H-[1,2,4]triazine-3,5-dione (10), a potential high affinity (K(i)

18 yl)piperazin-1-yl]butyl}-4-methyl-2H-[1,2,4 ]triazine-3,5-dione (9) and [(11)C]CH(3)OTf in 25 +/- 5%

19 use in promoting the cycloaddition of 1,2,3-triazine 4 with enamine 3 as the key step of a concise t

20 s 4-amino-3,7-dinitrotriazolo-[5,1-c][1,2,4] triazine 4-oxide (DPX-27), which is also predicted to be

21 synthesis of 3-methyl-5-phenylethynyl[1,2,4]triazine (4), 6-methyl-3-phenylethynyl[1,2,4]triazine (5

22 nylsulfinylphenyl)pyrazolo(1,5-alpha)-1,3, 5-triazine-4-monohydrate], a synthetic inhibitor of the en

23 riazine; 4,4',6,6'-tetra(azido)hydrazo-1,3,5-triazine; 4,4',6,6'-tetra(azido)azo-1,3,5-triazine; and

24 compounds, for example, 2,4,6-triazido-1,3,5-triazine; 4,4',6,6'-tetra(azido)hydrazo-1,3,5-triazine;

25 triazine (4), 6-methyl-3-phenylethynyl[1,2,4]triazine (5), and 5-methyl-3-phenylethynyl[1,2,4]triazin

26 l-4-(1,2,4-triazol-1-yl)pyrrolo[2,3-d][1,2,3]triazine-5-carbonitril e (17) was accomplished, and nucl

27 ture of 4-amino-7-benzylpyrrolo[2,3-d][1,2,3]triazine-5-carbonitrile (19) and 2-amino-1-benzylpyrrole

28 4-[1H-indazol-5-ylamino]pyrrolo[2,1-f][1,2,4]triazine-6-carbamates identified dual human epidermal gr

29 Lead optimization resulted in pyridinyl triazine 63, which exhibited >30-fold selectivity over a

30 zine (5), and 5-methyl-3-phenylethynyl[1,2,4]triazine (6a) as analogues of 2-methyl-6-(phenylethynyl)

31 ere 3-(3-methylphenylethynyl)-5-methyl[1,2,4]triazine (6b), 5-(3-chlorophenylethynyl)-5-methyl[1,2,4]

32 b), 5-(3-chlorophenylethynyl)-5-methyl[1,2,4]triazine (6c), and 3-(3-bromophenylethynyl)-5-methyl[1,2

33 and 3-(3-bromophenylethynyl)-5-methyl[1,2,4]triazine (6d).

34 -thiadiazole (4), phenyl- and diphenyl-1,3,5-triazines (7 and 8), and a trace quantity of diphenyl-1,

35 novel 2,7-disubstituted pyrrolo[2,1-f][1,2,4]triazine ALK inhibitors are described along with synthes

36 Trifluoro-1,3,5-triazine also participates in aryl centroid complexation

37 razines derivatives of [1,2,4]triazolo[1,5-a]triazine also possessed good oral efficacy in rodent mod

38 amic stability of three trimer isomers (an s-triazine, an aminohydroxypyrimidine, and an aminooxazoli

39 re, functional analysis of aminophenyl-1,3,5-triazine analogs elucidated structure-activity relations

40 along with X-ray structures with a series of triazine analogues aids in deciphering the mechanism by

41 nM) confirmed that the pyrrolo[2,1-f][1,2,4]triazine analogues are competitive with ATP.

42 hos pesticides with high selectivity against triazine and carbamate pesticides in approximately 10 mi

43 was modified with 2,6-diamino-4-phenil-1,3,5-triazine and characterized by FTIR, SEM and elemental an

44 etween 1,3,5-tris(2-hydroxyethyl)hexahydro-s-triazine and hydrogen sulphide, the principle by-product

45 etween 1,3,5-tris(2-hydroxyethyl)hexahydro-s-triazine and hydrogen sulphide, to be measured for a spe

46 cted from among industrial chemicals and the triazine and phenoxyacetic acid herbicide classes.

47 ecular coordination complexes (SCCs) bearing triazine and porphyrin faces with promising light-harves

48 nitio study of the interaction between 1,3,5-triazine and the fluoride, chloride, and azide ion at th

49 mplexes between a star-shaped tris(triazolyl)triazine and triphenylene-containing benzoic acids is de

50 n family, from a conveniently prepared 1,2,4-triazine and via a common tetrasubstituted pyridine inte

51 zadiene, complementary to the isomeric 1,2,4-triazines and 1,3,5-triazines, capable of dependable par

52 between substituted electron-deficient 1,2,3-triazines and a highly functionalized and chiral primary

53 six pyridinium rings fused with two central triazines and bridged by three paraxylylene units.

54 Both furo[3,4-d][1,2,3]triazines and dihydrotriazines exhibit good fluorescence

55 nisms of Diels-Alder reactions between 1,2,3-triazines and enamines have been explored with density f

56 Reactions between substituted 1,2,4-triazines and ketones were investigated.

57 od is reported for four standard test cases: triazines and pyrimidines binding to dihydrofolate reduc

58 y cocrystal structures of KDR inhibitors 34 (triazine) and 35 (nicotinamide).

59 ntaining RDX (hexahydro-1,3,5-trinitro-1,3,5-Triazine) and HMX (octahydro-1,3,5,7-tetranitro-1,3,5,7-

60 yl-oxazoles, -thiazoles, -imidazoles, -1,2,4-triazines, and -pyridines are available from the diazoke

61 ectron-demand Diels-Alder reactions of 1,2,3-triazines, and that these mechanisms can be altered by e

62 olyzed other N-substituted amino dihydroxy-s-triazines, and those with linear N-alkyl groups had high

63 azabenzenes (pyridine, three diazines, three triazines, and three tetrazines) with the ethylene dieno

64 ,5-triazine; 4,4',6,6'-tetra(azido)azo-1,3,5-triazine; and 2,5,8-tri(azido)-1,3,4,6,7,9,9b-heptaazaph

65 diazine, 1,3-diazine, 1,4-diazine, and 1,3,5-triazine are 110.4 +/- 2.0, 111.3 +/- 0.7, 113.4 +/- 0.7

66 ne, and dicyclopenta[b,d]pyrido[1,2-f][1,2,4]triazine are described.

67 2-Hydroxy-4,6-diamino-[1,3,5]triazines are described which are a novel class of poten

68 , neutral and basic pesticides (phenylureas, triazines) are more sensitive using APCI (especially pos

69 r studies demonstrate the versatility of the triazine as a modular scaffold to generate potent and se

70 Here we present the trifunctionalized 1,3,5-triazine as an ideal modular scaffold for generating lib

71 sing C3-symmetric 2,4,6-tri(4-pyridyl)-1,3,5-triazine as pore-partition agent in MIL-88 type (the acs

72 tin as the tumor-targeting moiety, and 1,3,5-triazine as the tripod splitter module, were designed an

73 common synthon affording access to pyridinyl triazines as the 4,4'-amino derivatives which are commer

74 no-1,3,5-triazine with 2,4,6-trichloro-1,3,5-triazine at 1.0-1.5 GPa and 500-550 degrees C and also t

75 self-reaction of 2-amino-4,6-dichloro-1,3,5-triazine at similar conditions.

76 2-chloro-4-ethylamino-6-isopropylamino-1,3,5-triazine (atrazine), 2.4-dichlorophenoxyacetic acid (2,4

77 mical genetic screenings were performed with triazine-based combinatorial libraries that include vari

78 Two triazine-based dendrimers were successfully prepared in

79 A series of 1,3,5-triazine-based estrogen receptor (ER) modulators that ar

80 Porous, fluorescent, covalent triazine-based frameworks (CTFs) are obtained in an unpr

81 fluoro-1H-indol-5-yloxy)pyrrolo[2,1-f][1,2,4]triazine-based inhibitors of vascular endothelial growth

82 Novel triazine-based microtubule inhibitors were discovered by

83 Triazine-based nanosheets are 1-2 nm in height and affor

84 ch rapidly isomerizes to a 3,4-dihydro-1,2,4-triazine-based nitrone, namely 6-phenyl-3-pyridin-2-yl-2

85 imiralisib), a potent 4,6-dimorpholino-1,3,5-triazine-based pan-class I PI3K inhibitor, which targets

86 activation chemistry was developed using the triazine-based reagent 4-(4,6-dimethoxy (1,3,5)triazin-2

87 eton for forming these bivalent compounds is triazine-based.

88 s as the point of intersection of multiple s-triazine biodegradative pathways and is completely essen

89 xplosive RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine) by microorganisms involves sequential reductio

90 The synthesis of a pyrazolo[1,5-a]-1,3,5-triazine C-nucleoside (dA(PT)), designed to form two hyd

91 tether from the imidazole N1 position to the triazine C3 proceed in excellent yields to produce 1,2,3

92 ry to the isomeric 1,2,4-triazines and 1,3,5-triazines, capable of dependable participation in invers

93 Because of the presence of the acceptor (triazine) center and strong donors in the arms (diarylam

94 high-throughput screening, aminophenyl-1,3,5-triazine CFTRact-K089 (1) that activated CFTR with EC50

95 An aminophenyl-1,3,5-triazine, CFTRact-K089, fully activated CFTR in cell cul

96 ies that act on the commercially important s-triazine class of compounds.

97 with the recent introduction of industrial s-triazine compounds such as atrazine and melamine into th

98 ng nitrate esters, nitroaromatics and cyclic triazine compounds.

99 salts) was developed and led to the desired triazines compounds, thus allowing a one-step economy in

100 NMR-based screen, we identified a series of triazine-containing compounds that bind weakly to ErmAM.

101 t the 6-position of the pyrrolo[2,1-f][1,2,4]triazine core gave potent compounds.

102 This [1,2,4]triazolo[1,5-a]triazine core structure has now been improved by incorpo

103 ster substituent of the pyrrolo[2,1-f][1,2,4]triazine core with heterocyclic bioisosteres, such as su

104 cules consist of an electron-deficient 1,3,5-triazine core with three fluorene arms substituted with

105 ative reactions of the growing dendrons with triazine cores and diamine linkers.

106 lized and unfunctionalized dendrons onto the triazine cores, a highly selective process due to the di

107 8-(substituted pyridyl)pyrazolo[1,5-a]-1,3,5-triazine corticotropin releasing factor receptor-1 (CRF(

108 of 8-(4-methoxyphenyl)pyrazolo[1,5-a]-1,3,5-triazine corticotropin releasing factor receptor-1 (CRF(

109 r, TCT hydrolyzes to 2,4-dicyano-6-hydroxy-s-triazine, DCTOH.

110 iterative synthesis of a second generation, triazine dendrimer with 12 protected amines on the perip

111 and host-guest chemistry of high-generation triazine dendrimers are described.

112 ed that the guest capacity of odd-generation triazine dendrimers increased until generation 7 but dec

113 benzene-functionalized high-molecular weight triazine dendrimers up to generation 9, demonstrating th

114 The [1,2,4]triazolo[1,5-a]triazine derivative 3, more commonly known in the field

115 onversion of new carboxamides (5 and 6) to s-triazine derivatives (7) was demonstrated in mouse and h

116 fluorinated nitrile 1e was converted to the triazine derivatives 2a and 2b by catalysis with Ag(2)O

117 The results suggest the metabolites, s-triazine derivatives 7, may be the active species of the

118 ent, selective, and orally efficacious 1,2,4-triazine derivatives have been identified using structur

119 A series of bis(morpholino-1,3,5-triazine) derivatives were prepared and optimized to pro

120 Length-monodisperse triazine-derivatized polymers were prepared on gram-scal

121 The effectiveness of novel sym-triazine-derived aggregation modulators (TAE-1, TAE-2) t

122 ound and the desired fused tricyclic 1,2,3,4-triazine display interesting thermal behavior and are pr

123 d 4-amino-3,7-dinitrotriazolo-[5,1-c][1,2,4] triazine (DPX-26).

124 The excited-state dynamics of an aniline-triazine electron donor-acceptor dyad with an alkyne spa

125 in that it contains an amine reactive group (triazine ester) targeting the N-terminus and epsilon-ami

126 ing groups (-CO2R) at C4 and C6 of the 1,2,3-triazine even if C5 is unsubstituted (Me or H), highligh

127 so showed an increase in resistance to the s-triazine family of herbicides although this feature did

128 Covalent triazine frameworks (CTFs) are normally synthesized by i

129 mily of hexaazatriphenylene-based conjugated triazine frameworks (CTFs) for efficient CO2 capture.

130 ed, but not eliminated, by the withdrawal of triazines from conventional maize cropping.

131 ching of RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine) from particulates deposited in live-fire milit

132 ractions upon binding to the kinases via its triazine functional group, which is considerably larger

133 ituted 4-(phenylamino)-pyrrolo[2,1- f][1,2,4]triazines has been discovered.

134 this series of [1,2,4]triazolo[1,5-a][1,3,5]triazine have now been shown to be orally active in the

135 s piperazine series of [1,2,4]triazolo[1,5-a]triazine have now been shown to have good oral bioavaila

136 ves of 2-furanyl[1,2,4]triazolo[1,5-a][1,3,5]triazine have recently been demonstrated to be potent an

137 ric 2-(hydroxytolyl)-4,6-dimethylamino-1,3,5-triazines have been synthesized in high yields in a cont

138 rse electron-demand Diels-Alder reactions of triazines have wide applications in bioorthogonal chemis

139 o been applied to the preparation of a 1,3,5-triazine having three different substituents.

140 Here, we forecast weed abundances in post-triazine herbicide regimes.

141 on of 14C-labeled urinary metabolites of the triazine herbicide, atrazine, and the analytical perform

142 s-Triazine herbicides (atrazine, ametryn) are groundwater

143 For both triazine herbicides and carbamate pesticides samples, dr

144 s of separation efficiency and resolution of triazine herbicides are presented and discussed.

145 Withdrawal of the triazine herbicides atrazine, simazine and cyanazine fro

146 ganochlorine insecticides and slightly polar triazine herbicides from soil is also presented and comp

147 hine and propaphenone in untreated urine and triazine herbicides in a soil extract.

148 Here we analyse effects of applications of triazine herbicides in conventional maize regimes on key

149 evelopment of time and location profiles for triazine herbicides in environmental samples.

150 ed for predicting the separation behavior of triazine herbicides in partial-filling MEKC.

151 As model compounds four selected triazine herbicides namely, simazine, atrazine, secbumet

152 eference adsorbent graphite was conducted of triazine herbicides, substituted anilines, heterocyclic

153 mpletely essential for microbial growth on s-triazine herbicides.

154 e four FSE sites analysed that used only non-triazine herbicides.

155 ediates generated during the metabolism of s-triazine herbicides.

156 ling reaction, were used to assemble various triazine-heteroaryl analogues effectively.

157 The fact that only two pyrrolo[2,3-d][1,2,3]triazines heterocycles had been reported in the literatu

158 phenylene vinylene) derivative with a ureido-triazine hydrogen bonding unit self-assembles into rows

159 ring nitrogen was protonated in the enzyme s-triazine hydrolase (TrzN) where (iii) TrzN crystal struc

160 TrzN, the broad-specificity triazine hydrolase from Arthrobacter and Nocardioides sp

161 Atrazine chlorohydrolase, TrzN (triazine hydrolase or atrazine chlorohydrolase 2), initi

162 ionation pattern for identifying microbial s-triazine hydrolysis in the environment caused by multipl

163 amino acids, sugars, organic acids, amides, triazine, imidazole, protein, and biological tissue.

164 synthesis of the layered bulk material poly(triazine imide), PTI, followed by one-step liquid exfoli

165 rrole with 2,4,6-tris(trifluoromethyl)-1,3,5-triazine in THF-d(8) to give a pyrrolo[2,3-d]pyrimidine

166 erized by NMR and MS and was identified as a triazine in which the pyrimidine ring was oxidatively de

167 cient methodology for the synthesis of 1,3,5-triazines in good to excellent yields under transition-m

168 synthesis of highly fused furo[3,4-d][1,2,3]triazines in good-to-excellent yields under mild conditi

169 form 2,4-disusbstituted-6-substituted 1,3,5-triazines in moderate to good yields.

170 Dispersion (MSPD) for determination of nine triazines in mussels has been optimised in terms of the

171 xplosive RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine) in an aquifer near the Iowa Army Ammunition Pl

172 henyl)-1H-p yrazol-4-yl)imidazo[1,5-f][1,2,4]triazine, in nonhuman primates.

173 otoluene, and hexahydro-1,3,5-trinitro-1,3,5-triazine indicated that a potential of - 1500 mV vs Ag/A

174 ectron demand Diels-Alder reactions of 1,2,3-triazines is disclosed, including an examination of the

175 A new class of bioorthogonal reagents, 1,2,4-triazines, is described.

176 dyl-based ligands, 2,4,6-tri-4-pyridyl-1,3,5-triazine (L1) and 5,10,15,20-tetra(4-pyridyl)-21H,23H-po

177 aled that the oxindole-pyrrolo[2,1- f][1,2,4]triazine lead 2a displayed potent enzyme inhibition (IC

178 nal combinatorial synthesis of a high-purity triazine library was demonstrated.

179 ibition of regeneration, we screened a novel triazine library, based on the ability of compounds to i

180 y a phenanthroline-derived quadridentate bis-triazine ligand are described.

181 first 1:2 bis-complex of a quadridentate bis-triazine ligand to be characterized by crystallography.

182 -Alder reaction between imidazoles and 1,2,4-triazines linked by a trimethylene tether from the imida

183 target, a generation-13 dendrimer comprising triazines linked by diamines, is stable across ranges of

184 nctional monomer (2,4,6-trisacrylamido-1,3,5-triazine), mixed templates (ascorbic acid and dopamine),

185 on reaction revealed that the inherent 1,2,3-triazine mode of cycloaddition (C4/N1 vs C5/N2) as well

186 Simple organic cooperative assembly of triazine molecules leads to three-dimensional macroscopi

187 lamino)-4-hydroxy-6-(N-isopropylamino)-1,3,5-triazine] N-ethylaminohydrolase (AtzB) is the sole enzym

188 high-throughput screen of cruzain identified triazine nitriles, which are known inhibitors of other c

189 Hydrogen bonding between one of the triazine nitrogens and the backbone NH of the Met109 res

190 The pyrrolo[2,1-f][1,2,4]triazine nucleus was identified as a novel kinase inhibi

191 ic oxazole formation over the more customary triazine or pyrimidine trimers.

192 of arylhydrazines, o-aminoacetophenones, and triazines or nitriles.

193 ports have misassigned these structures as s-triazines or pyrimidines.

194 but not RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine) or 2,6-DNT (2,6-dinitrotoluene).

195 ction initially produces a population of sym-triazine partitioned between the 3s Rydberg and pi* <--

196 In the present work, the solubilities of the triazine pesticides atrazine, cyanazine, and simazine we

197 em temperature increases the solubilities of triazine pesticides in subcritical water.

198 rature of the water, the solubilities of the triazine pesticides increased approximately 3-fold in pu

199 pite stereoregio backbone heterogeneity, the triazine polymers bind T/U-rich DNA or RNA with nanomola

200 d and exothermic decomposition of a reactive triazine precursor, C 3N 3(NHCl) 3, was examined by bypr

201 2-substituted imidazoles with various 1,2,4-triazines produced both imidazo[4,5-c]pyridines (3-deaza

202 ducts, the suggested precursors of the 1,3,5-triazine products 7 and 8.

203 nd compound B led to the discovery of [1,3,5]triazine-pyridine as a new series of potent CDK inhibito

204 s induced by charge exchange between the sym-triazine radical cation and cesium.

205 es containing hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) and 2,4,6-trinitrotoluene (TNT) from poly

206 hmarks, such as 1,3,5-trinitroperhydro-1,3,5-triazine (RDX) and octahydro-1,3,5,7-tetranitro-1,3,5,7-

207 ne compounds, hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) and octahydro-1,3,5,7-tetranitro-1,3,5,7-

208 specific for hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) combined into a single device.

209 ively removes hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) from groundwater but generates RDX-laden

210 Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) is a common constituent of military explo

211 1,3,5-Trinitroperhydro-1,3,5-triazine (RDX) is a principal component of plastic explo

212 Hexahydro-1,3,5-trinitro-1,3,5,-triazine (RDX) is a toxic and mobile groundwater contami

213 The explosive Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) is known to be degraded aerobically by va

214 awing explosive 1,3,5-trinitroperhydro-1,3,5-triazine (RDX) produced no response.

215 losive molecule 1,3,5-trinitroperhydro-1,3,5-triazine (RDX) via combined nanomechanical photothermal

216 uene (TNT), and 1,3,5-trinitroperhydro-1,3,5-triazine (RDX)).

217 azocine (HMX), 1,3,5-trinitroper-hydro-1,3,5-triazine (RDX), 2,4,6-trinitrotoluene (TNT), 2-amino-4,6

218 rgetic compound 1,3,5-trinitroperhydro-1,3,5-triazine (RDX), a known neurotoxicant.

219 oluene (TNT), hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), and pentaerythritol tetranitrate (PETN)

220 on of the explosives trinitrohexahydro-1,3,5-triazine (RDX), octahydro-1,3,5,7-tetranitro-1,3,5,7-tet

221 ermination of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), octahydro-1,3,5,7-tetranitro-1,3,5,7-tet

222 1,3,5-trinitroperhydro-1,3,5-triazine (RDX), octahydro-1,3,5,7-tetranitro-1,3,5,7-tet

223 nvironment of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), one of the most widely used military exp

224 oglycerin (NG), 1,3,5-trinitroperhydro-1,3,5-triazine (RDX), pentaerythritol tetranitrate (PETN), tri

225 ), and 0.3 mm hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX).

226 rior to that of 1,3,5-trinitroperhydro-1,3,5-triazine (RDX).

227 ior to those of 1,3,5-trinitroperhydro-1,3,5-triazine (RDX).

228 eacted 1,3,5-tris(2-hydroxyethyl)hexahydro-s-triazine remaining; the only source of inorganic sulphid

229 catalyze dehalogenation of halo-substituted triazine ring compounds and had no activity with melamin

230 the terminal reaction during metabolism of s-triazine ring compounds by bacteria.

231 Stability of the triazine ring in aqueous solution was not improved in th

232 identification and (ii) suggested that the s-triazine ring nitrogen was protonated in the enzyme s-tr

233 alyze the sequential hydrolytic removal of s-triazine ring substituents from the herbicide atrazine t

234 The cleavage of the triazine ring under previously developed conditions1-6 r

235 for formation of the 1,4-dihydrobenzo[1,2,4]triazine ring was investigated using the B3LYP/6-31G(2d,

236 Substrates required a monohydroxylated s-triazine ring with a minimum of one primary or secondary

237 ive complexes for nucleophilic attack on the triazine ring, and pi-stacking interactions (with azide)

238 Donor substituents were attached on the triazine ring, including pyrazolyl-substituted anilines

239 acement of a chlorine substituent from the s-triazine ring.

240 oducts arising from over-substitution of the triazine ring.

241 st compounds 5-methyl-3-phenylethynyl-[1,2,4]triazine (RTI-4229-707), 5-methyl-3-(4-phenoxy-phenyleth

242 , 5-methyl-3-(4-phenoxy-phenylethynyl-[1,2,4]triazine (RTI-4229-766), and 3-(3-methylphenylethynyl)-5

243 3-(2,5-dimethylphenylethynyl)-5-methyl[1,2,4]triazine (RTI-4229-785) and 3-(2-methylphenylethynyl)-5-

244 nd 3-(3-methylphenylethynyl)-5-methyl-[1,2,4]triazine (RTI-4229-787) resulted in a dose-dependent blo

245 and 3-(2-methylphenylethynyl)-5-methyl[1,2,4]triazine (RTI-4229-828) were totally inactive.

246 We also showed that, for the triazine samples, the T3C approach gave a better separat

247 The enhanced stability of the triazine scaffold enabled its direct use in recombinant

248 novel 2,7-disubstituted-pyrrolo[2,1-f][1,2,4]triazine scaffold has been designed as a new kinase inhi

249 validation of this new pyrrolo[2,1-f][1,2,4]triazine scaffold will be described for inhibitors of an

250 n maps confirmed triphenylene/tris(triazolyl)triazine segregation into hexagonal sublattices and latt

251 ctivity studies in the pyrazolo[1,5-a]-1,3,5-triazine series led to the discovery that compound 11i (

252 side chain provides a proton to N-1 of the s-triazine substrate to facilitate nucleophilic displaceme

253 fferent relative activities with different s-triazine substrates.

254 ase had no detectable activity with the halo-triazine substrates.

255 The triazine-TCO reaction can also be used in tandem with ot

256 ent cyanuric chloride (2,4,6-trichloro-1,3,5-triazine, TCT) catalyzed approach for the synthesis of 2

257 Chemical reduction of 2,4,6-tricyano-1,3,5-triazine, TCT, results in the formation of an unstable r

258 ,6-trichloro-1,3,5-triazine were used--1,3,5-triazines that had leaving groups.

259 amorphous carbon nitride networks formed by triazine thermolysis reactions.

260 carbon nitride materials that are formed via triazine thermolysis.

261 he chelating reagent 2,4,6-trimercapto-1,3,5-triazine (TMT) in the first step and separated by mixed

262 and water, with another equivalent of 1,3,5-triazine to give compounds containing three linked heter

263 d from rigorous structural investigations of triazine to heptazine thermal conversion processes have

264 nhibitors by a fused imidazole ring with the triazine to provide imidazo[1,2-a][1,3,5]triazines.

265 n, including core scaffold modification from triazine to purine, improved the in vitro potency agains

266 ighly debated three-body dissociation of sym-triazine to three hydrogen cyanide molecules.

267 ently reacted to 2,4,6-tri(2'-pyridyl)-1,3,5-triazine (TPTZ) then measured at 593 nm.

268 I) acceptor with 2,4,6-tris(4-pyridyl)-1,3,5-triazine (TPyT) or 5,10,15,20-Tetra(4-pyridyl)-21H,23H-p

269 amed 2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine (TTBP-TAZ) is reported for the first time in pl

270 One popular precursor building block is the triazine unit (C 3N 3), and most postulated amorphous CN

271 network structures are based on cross-linked triazine units.

272 n of highly substituted pyridines from 1,2,4-triazines via the inverse-electron-demand Diels-Alder re

273 2,4,6-Tris(dimethylamino)-1,3,5-triazine was prepared to complete the series; this is, h

274 If excess 1,3,5-triazine was present the initial S(N)Ar product reacted

275 for the preparation of 6-unsubstituted 1,2,4-triazines was also developed.

276 Reaction of 3-aminopyrrole with seven 1,3,5-triazines was studied in a one-step reaction (in situ fo

277 eries of hybrid analogues of monastrol-1,3,5-triazine were designed and developed via one-pot synthes

278 en 2,4,6-trifluoro- or 2,4,6-trichloro-1,3,5-triazine were used--1,3,5-triazines that had leaving gro

279 eral high-affinity 2-anilinopyrimidines and -triazines were discovered, some of which had superior ph

280 Pyridyl-substituted 1,3,5-triazines were synthesized in good to excellent yields v

281 RAP reagent contains 2,4,6-tris(2-pyridyl)-s-triazine, which forms a blue-violet complex ion in the p

282 id-mediated cyclodehydration gives the fused triazines, which upon alkali treatment afford the desire

283 solid-state reaction of 2,4,6-triamino-1,3,5-triazine with 2,4,6-trichloro-1,3,5-triazine at 1.0-1.5

284 of the C6 ester of the pyrrolo[2,1- f][1,2,4]triazine with amides afforded compounds with increased p

285 hetic scheme was developed to derivatize the triazine with an electrophile for covalent modification

286 4'-methylphen-2'-yl)-4,6-dimethylamino-1,3,5-triazine with ICl provides species differing in the posi

287 ine, pyridazine, pyrimidine, pyrazine, and s-triazine with N and O atoms are studied both experimenta

288 steps in the IEDDA cascade reaction of 1,3,5-triazines with amino-containing dienophiles has been obt

289 s to pyridyl (or pyridone)-substituted 1,3,5-triazines with high potential in various fields of appli

290 amination of functionalized pyridinyl-1,2,4-triazines with low catalyst/ligand loadings enabling the

291 on the cycloaddition reactivity of the 1,2,3-triazine without altering, and perhaps even enhancing, t