ライフサイエンスコーパス: triclosan

1 LR ligands in the presence and/or absence of triclosan.

2 DEET, carbamazepine, dilantin, naproxen, and triclosan.

3 55, which is abrogated by pre-treatment with triclosan.

4 and exposure history alter the influence of triclosan.

5 nd identified sociodemographic predictors of triclosan.

6 rnal concentrations followed by tonalide and triclosan.

7 CI: 0.97, 1.4) per log(10) unit increase in triclosan.

8 phthalate, and 8,000-24,000 ppm (range) for triclosan.

9 thpaste with polymer and fluoride containing triclosan.

10 to those achieved with toothpaste containing triclosan.

11 nol, ibuprofen, diclofenac, bisphenol A, and triclosan.

12 containing chlorophenol side-chains such as triclosan.

13 , ketorolac, and Total toothpaste containing triclosan.

14 e oxidation of either mono- or dichlorinated triclosan.

15 is the target of the antibacterial compound, triclosan.

16 , ethionamide, ofloxacin, thiolactomycin and triclosan.

17 enzyme has the requisite amino acids to bind triclosan.

18 ifference in affinities of FabI and InhA for triclosan.

19 cobacterial enoyl reductases are targets for triclosan.

20 san, show significantly reduced affinity for triclosan.

21 ficiently inhibited by low concentrations of triclosan.

22 was also NADH dependent but not inhibited by triclosan.

23 nd propyl parabens), 2,5-dichlorophenol, and triclosan.

24 children was also positively associated with triclosan.

25 als treated with the lowest doses of MPB and triclosan.

26 combination of rifampicin, sparfloxacin and triclosan.

27 on balloons were inflated with a solution of triclosan (10 g/L), the catheters drained freely for at

28 none-3 (2-hydroxy-4-metoxybenzophenone); and triclosan (2,4,4'-trichloro-2'-hydroxyphenyl ether).

29 analytes studied (gemfibrozil, nonylphenol, triclosan, 2,4,6-trichlorophenol, and naphthenic acids),

30 We detected benzophenone-3, triclosan, 2,4-dichlorophenol, 2,5- dichlorophenol, and

31 available positive control dentifrice (0.30% triclosan/2.0% Gantrez copolymer).

32 ct concentrations (LOAECs) were 1.04 muM for triclosan, 3.17 muM for triclocarban, 0.372 muM for bis-

33 at were amended with lower concentrations of triclosan (5 mg/kg and 50 mg/kg) initially diverged and

34 Triclosan [5-chloro-2-(2,4-dichlorophenoxy)phenol; TCS]

35 inary inhibition studies, we have shown that triclosan, 5-ethyl-2-phenoxyphenol (EPP), and 5-chloro-2

36 Triclosan, a common antibacterial additive used in consu

37 ng on the availability of vanadate salts and triclosan, a component of PIA.

38 s chlorination experiments were performed on triclosan, a previously studied environmental contaminan

39 This enzyme is also sensitive to triclosan, a synthetic antimicrobial diphenyl ether.

40 rophenol, pyraclostrobin, sulfasalazine, and triclosan, achieving detection limits of 0.07, 0.24, 10.

41 R with triclosan and NAD(+) which reveal how triclosan acts as a site-directed, picomolar inhibitor o

42 eplacement of A197 with Met has no impact on triclosan affinity, indicating that differences in the s

43 ased concomitantly with the disappearance of triclosan after a 15 min reaction, the sustained toxicit

44 At the end of the experiment, all triclosan-amended Archaea communities had diverged from

45 Triclosan amendment caused all of the Bacteria and Archa

46 ficantly increased with the level of urinary triclosan among male subjects (odds ratio for third vs f

47 ies indicate that the antibacterial compound triclosan, an additive in many personal care products, i

48 Exposure to triclosan, an antimicrobial used in many consumer produc

49 AD(+), and as ternary complexes bound to the triclosan analogs 1 and 2 with NADH.

50 The x-ray crystal structures of five triclosan analogs, in addition to that of the isoniazid-

51 In this paper, new coumarin-based triclosan analogues are reported and their biological pr

52 hod to calculate the affinity of a series of triclosan analogues for the E. coli enoyl reductase FabI

53 ly reduce the teratogenicity of bisphenol A, triclosan and 17alpha-ethinyl estradiol without generati

54 ditional evidence for an association between triclosan and allergy.

55 eactions with free chlorine alone, while for triclosan and bisphenol A the free iodine mediated trans

56 Using triclosan and chlorophene as probe compounds, pseudofirs

57 It is clear, however, that triclosan and CTDs are the dominant source of these cong

58 ing one between the ubiquitous antimicrobial triclosan and erm(X), a 23S rRNA methyltransferase impli

59 A nonmonotonic association was observed for triclosan and girls' adiposity; however, it was due to e

60 dren and exposure to the antibacterial agent triclosan and having filaggrin (FLG) loss-of-function mu

61 Triclosan and hexachlorophene inhibited both ecFabI and

62 Triclosan and its analogs 1 and 2 killed multidrug-resis

63 persive SPE cleanup procedure for extracting triclosan and methyltriclosan from fish roe and surimi s

64 TiO(2), precursor-complex formation between triclosan and MnO(2) was much slower and likely became t

65 lexes of E. coli and Brassica napus ENR with triclosan and NAD(+) which reveal how triclosan acts as

66 ry complex with NADH, a ternary complex with triclosan and NAD(+), and as ternary complexes bound to

67 trend toward an inverse association between triclosan and paraben exposure and allergic sensitizatio

68 association between prenatal and early-life triclosan and paraben exposure and childhood allergic di

69 However, levels of the antimicrobial EDCs triclosan and parabens were significantly associated wit

70 In cross-sectional studies triclosan and parabens, ubiquitous ingredients in person

71 ol and phenanthrene) and additive chemicals (Triclosan and PBDE-47).

72 d children, we examined associations between triclosan and personal-care product use.

73 sed with the level of the antimicrobial EDCs triclosan and propyl and butyl parabens (P </= .04).

74 mechanism for the antibacterial activity of triclosan and substantiate the hypothesis that its activ

75 samples spiked with the model "unknown" EDCs triclosan and tetrabromobisphenol-A.

76 nhA, Y156F FabI has a decreased affinity for triclosan and the inhibitor binds to both E.NAD(+) and E

77 results in markedly increased resistance to triclosan and the purified enzyme is much more resistant

78 ewed research, this statement concludes that triclosan and triclocarban are environmentally persisten

79 The polychlorinated aromatic antimicrobials triclosan and triclocarban are in widespread use for kil

80 The Florence Statement on Triclosan and Triclocarban documents a consensus of more

81 other hazards to humans and ecosystems from triclosan and triclocarban is presented along with recom

82 Triclosan and triclocarban were found in the extracts of

83 Two common (triclosan and triclocarban) and four emerging (2,4,5 tri

84 rds, among others transformation products of triclosan and triclocarban.

85 of demonstrated benefit from common uses of triclosan and triclocarban.

86 urinary chemical concentrations of parabens, triclosan and triclorcarban in relation to TTP; chemical

87 and analyzed the interaction of saFabI with triclosan and two related diphenyl ether inhibitors.

88 nols (e.g., bisphenol A, benzophenone-3, and triclosan) and parabens is widespread in the population.

89 ting chemicals such as phthalates, parabens, triclosan, and benzophenone-3 (BP-3) for adolescent girl

90 f the phenolic compounds 2,4-dichlorophenol, triclosan, and bisphenol A in chlorinated waters contain

91 nalyzed for phthalate metabolites, parabens, triclosan, and BP-3 using high-performance liquid chroma

92 labeled to be free of phthalates, parabens, triclosan, and BP-3, can reduce personal exposure to pos

93 g10 concentrations of widely monitored HHCB, triclosan, and carbamazepine explained 71-82% of the var

94 e been relatively well studied, bisphenol A, triclosan, and ibuprofen.

95 m of the bacteriostatic agents triclocarban, triclosan, and its transformation product methyl triclos

96 Copper, permethrin, chromium, triclosan, and lead were also important.

97 ntaminants as malathion, glyphosate, diuron, triclosan, and nonylphenol were assessed.

98 e class of antibacterial agents, the biocide triclosan, and one of the targets for the front-line ant

99 ons and urinary bisphenol A, benzophenone-3, triclosan, and paraben levels in male and female childre

100 scopy results indicate that phenol, aniline, triclosan, and related byproducts are associated with th

101 ), bisphenols, benzophenone-type UV filters, triclosan, and triclocarban are used in a variety of con

102 l phthalate (DEP), methyl paraben (MPB), and triclosan] and urine and serum concentrations of their r

103 n urinary concentrations of triclocarban and triclosan, another commonly used antibacterial agent.

104 n northern MN, the four dioxins derived from triclosan are present prior to the patent of triclosan,

105 e" complex accounts for the effectiveness of triclosan as a FabI inhibitor and illustrates that mutat

106 Using the biocide triclosan as a selective agent, several triclosan-resist

107 Triclosan became impregnated throughout the silicone cat

108 ther exposures (total parabens, bisphenol A, triclosan, benzophenone-3, total phthalates, and 2,4-DCP

109 ination Survey in which urinary bisphenol A; triclosan; benzophenone-3; propyl, methyl, butyl, and et

110 These data define the structural basis of triclosan binding to PfENR and will facilitate structure

111 Triclosan binding to the E.NADH form of F203L can also b

112 ly, the Y158 hydroxyl group is important for triclosan binding, suggesting that triclosan binds in si

113 rtant for triclosan binding, suggesting that triclosan binds in similar ways to both InhA and EnvM.

114 Triclosan binds preferentially to the E.NAD(+) form of t

115 scence binding experiments, we conclude that triclosan binds to the enzyme-NAD(+) product complex whi

116 strate specificity that encompasses not only triclosan but the detergent SDS, which are often used to

117 YgaA was reversibly inhibited by triclosan, but did not form the stable ternary complex c

118 0156-PA0157-PA0158 pump, which only effluxed triclosan, but not closely related compounds, antibiotic

119 The replacement of the ether linkage in triclosan by a carbon bridge in hexachlorophene prevente

120 explain the observed adsorption behavior of triclosan by the binary oxide mixtures and single oxides

121 to strong adsorption and slow desorption of triclosan by TiO(2), precursor-complex formation between

122 red to the wild-type enzyme, indicating that triclosan can stimulate the emergence of isoniazid-resis

123 Previously exposed (to triclosan) communities were amended with 5, 50, and 500

124 We show that the AcpP-triclosan complex demonstrates nM binding, inhibits in v

125 m the control communities, regardless of the triclosan concentration added.

126 h percentile, and 4-fold higher than maximum triclosan concentration that has been detected in U.S. b

127 zation among those in the fourth quartile of triclosan concentration was 2.0 [95% confidence interval

128 JK) Delta(mexXY) strain PAO509 to increasing triclosan concentrations and derived a resistant strain,

129 Triclosan concentrations decreased by 35.7% (95% CI: -53

130 Our results suggest that urinary triclosan concentrations have modest stability over week

131 erns, variability, and predictors of urinary triclosan concentrations in 389 mother-child pairs enrol

132 Triclosan concentrations were associated with allergic s

133 All eight triclosan conjugates identified in the cell cultures wer

134 aste regimen: control dentifrice (n = 21) or triclosan-containing dentifrice ([CT] n = 18).

135 tracts of intact carrot plants cultivated on triclosan contaminated soils.

136 frice in reducing gingivitis compared to the triclosan/copolymer control in this partially supervised

137 L and root caries versus the sodium fluoride/triclosan/copolymer control in xerostomic patients.

138 This study evaluates the effect of triclosan/copolymer dentifrice on the 6-month clinical r

139 the limits of the present study, the use of triclosan/copolymer dentifrice promoted additional clini

140 n = 15) subjected to FMUD and daily use of a triclosan/copolymer dentifrice.

141 taphosphate dentifrice to a positive control triclosan/copolymer dentifrice.

142 ve control dentifrice (sodium fluoride/0.30% triclosan/copolymer) in 440 medication-induced xerostomi

143 es were amended with 5, 50, and 500 mg/kg of triclosan, corresponding to the median, 95th percentile,

144 This research suggests that triclosan could inhibit methane production in anaerobic

145 he accumulation rates and temporal trends of triclosan, CTDs, and dioxins in aquatic sediments were f

146 ources recorded increasing concentrations of triclosan, CTDs, and their derived dioxins since the pat

147 of waters to these compounds, the levels of triclosan, CTDs, and their derived dioxins were determin

148 Overall, concentrations of triclosan, CTDs, and their dioxins were higher in small-

149 2) dentifrice relative to a positive control triclosan dentifrice for prevention of clinical attachme

150 icrobial agent in handsoaps, and chlorinated triclosan derivatives (CTDs, formed during disinfection

151 positive bacteria are naturally resistant to triclosan due to the presence of the triclosan-resistant

152 mains of TriA and TriB differentially affect triclosan efflux and assembly of the complex.

153 may function as a two-component RND pump for triclosan efflux but must associate with OprM to form a

154 , but not OprM, for assembly of a functional triclosan efflux pump.

155 Triclosan efflux required neither of the outer membrane

156 he function, composition and assembly of the triclosan efflux transporter TriABC-OpmH from Pseudomona

157 ded parabens, phthalates, bisphenol A (BPA), triclosan, ethanolamines, alkylphenols, fragrances, glyc

158 Controls for the MPB and triclosan experiments were animals treated with olive oi

159 We investigated whether triclosan exposure was associated with allergic sensitiz

160 e residue, with Phe, reduces the affinity of triclosan for the enzyme and results in noncompetitive i

161 netic selection experiments, the affinity of triclosan for the FabI mutants G93V, M159T, and F203L is

162 e) and one personal care product ingredient (triclosan) for the oligochaete Lumbriculus variegatus.

163 Uptake of Triclosan from PVC diminished the ability of worms to en

164 y methylparaben, propylparaben, bisphenol A, triclosan, galaxolide, and 4- methylbenzilidene camphor

165 stic actions, and the personal care products triclosan, galaxolide, and nonylphenol are representativ

166 ESR increased at a slower rate in the triclosan group (P approximately 0.06) and was less like

167 te than either patients with diabetes in the triclosan group or patients without diabetes in each gro

168 atins but not anti-inflammatory drugs in the triclosan group versus the placebo group.

169 of </=5%, bisphenol A, caffeine, NP, OP, and triclosan had false positive rates >15%.

170 The phototransformation of triclosan has been a matter of longstanding interest due

171 analysis of the inhibition of the enzyme by triclosan has been conducted showing that triclosan is a

172 crobial agents such as stannous fluoride and triclosan have been incorporated into dentifrice formula

173 expressing FabI(Y147H) was also resistant to triclosan; however, the strain expressing FabI(M99T) was

174 very little information, however, about how triclosan impacts microbial communities in anaerobic dig

175 We investigated how triclosan impacts the community structure, function and

176 Triclosan-impregnated sutures did not statistically sign

177 : 0.21-5.43; P = 0.93; I = 44%) CONCLUSIONS: Triclosan-impregnated sutures do not decrease the rate o

178 mized controlled trials (RCTs) investigating triclosan-impregnated sutures were conducted.

179 decrease the rates of SSIs may be the use of triclosan-impregnated sutures.

180 We detected triclosan in >70% of urine samples.

181 nd their derived dioxins since the patent of triclosan in 1964.

182 We quantified triclosan in 3 urine samples collected from women betwee

183 se oxide [MnOx(s)] with phenol, aniline, and triclosan in batch experiments using X-ray photoelectron

184 elates with resistance to the common biocide triclosan in Mycobacterium smegmatis, binding to form th

185 rs of diethyl phthalate, methyl paraben, and triclosan in rats.

186 tylmethoxydibenzoylmethane, triclocarban and triclosan in the aquatic environment.

187 Cyperin mimicked the binding of triclosan in the binding pocket of ENR.

188 yl paraben, benzophenone-3, bisphenol A, and triclosan in urine collected during 1997-2006 from 50 pa

189 of alkyl esters of p-hydroxybenzoic acid and triclosan in vitro on the basis of steady-state fluoresc

190 s, benzophenone-3, BPA, two dichlorophenols, triclosan) in spot urine samples collected during pregna

191 by triclosan has been conducted showing that triclosan is a competitive inhibitor with respect to NAD

192 t with previous studies, we report here that triclosan is a slow, reversible, tight binding inhibitor

193 Triclosan is a widespread antimicrobial agent that accum

194 Furthermore, the results confirm that triclosan is an excellent tool for the study of RND mult

195 Triclosan is known to cause severe oxidative stress, and

196 phthalates and phenols such as parabens and triclosan, is ubiquitous within the U.S. general populat

197 nts was assessed to exceed the amount of the triclosan itself by a factor of 5.

198 unexposed communities were exposed to 500 mg triclosan/kg, function was maintained, but the abundance

199 Triclocarban and methyl triclosan lack a phenolic group and remained unaltered i

200 as a significant interaction between sex and triclosan level, with male subjects being more likely to

201 trogenic activity of CPC, BAK, rotenone, and triclosan may be related to their mitochondrial inhibito

202 Mass ratios of DCC-to-TCC and of methyl-triclosan (MeTCS)-to-TCS, serving as indicators of trans

203 Triclosan, methyl paraben, and propyl paraben concentrat

204 vious studies: 1,735 (DEP), 1,050 (MPB), 50 (triclosan) mg/kg/day.

205 y where the enzyme contained either a single triclosan molecule, in a configuration typical of other

206 al ENR:triclosan structures, or harbored two triclosan molecules bound to the active site.

207 tal, Brisbane, Australia, were randomized to triclosan (n = 193) or placebo (n = 190) groups and asse

208 rmine effects of the anti-inflammatory agent triclosan on the TLR-hyper-inflammatory phenotype, prima

209 Whereas cyperin was much less potent than triclosan on this target site, their ability to cause li

210 In the lake with no wastewater input, no triclosan or CTDs were detected.

211 association between prenatal and early-life triclosan or paraben concentrations and childhood asthma

212 sociations of maternal plasma or child urine triclosan or paraben concentrations with asthma or recur

213 The differential effects of triclosan or paraben exposure on allergic sensitization

214 her organic chemicals (i.e., benzophenone-3, triclosan, parabens) in human urine, milk, and serum to

215 ations of antimicrobial chemicals, which for triclosan ranged from 0.5 to 1970 ng/g dust.

216 Triclosan released after conjugation to octaarginine via

217 but only the association in males exposed to triclosan remained statistically significant after corre

218 ss correlation coefficients (ICCs) to assess triclosan reproducibility and identified sociodemographi

219 Triclosan reproducibility was fair to good during pregna

220 ed, but the abundance of a gene encoding for triclosan resistance (mexB) increased.

221 aeruginosa achieves high-level (MIC>1 mg/ml) triclosan resistance either by constitutive expression o

222 haracterization of a DNA fragment conferring triclosan resistance from one of these mutants revealed

223 tation in the chromosomal safabI gene led to triclosan resistance in S. aureus; however, these strain

224 this bacterium's high intrinsic and acquired triclosan resistance.

225 ts) defect in E. coli and conferred complete triclosan resistance.

226 The triclosan-resistant ecFabI(G93V) protein was also refrac

227 tant to triclosan due to the presence of the triclosan-resistant enoyl-ACP reductase isoforms, FabK a

228 The triclosan-resistant mutant contained a single nucleotide

229 cide triclosan as a selective agent, several triclosan-resistant mutants of a susceptible Pseudomonas

230 A triclosan-resistant target enzyme and perhaps other mech

231 In this study, photolysis of triclosan resulted in several primary photoproducts incl

232 f InhA with the broad spectrum antimicrobial triclosan revealed a unique stoichiometry where the enzy

233 Importantly, triclosan's anti-inflammatory property is effective in a

234 ents of our optimization program to decouple triclosan's specific FabI effect from its nonspecific cy

235 ferent MFPs, TriA and TriB, are required for triclosan/SDS resistance mediated by TriABC-OpmH.

236 the increased tetracycline, penicillin, and triclosan sensitivities resulted from repression of the

237 in resistance of Mycobacterium smegmatis to triclosan, show significantly reduced affinity for tricl

238 e ability to improve the in vitro potency of triclosan significantly by replacing the suboptimal 5-ch

239 Here we show that triclosan specifically inhibits InhA, the enoyl reductas

240 configuration typical of other bacterial ENR:triclosan structures, or harbored two triclosan molecule

241 triclosan are present prior to the patent of triclosan, suggesting a secondary source.

242 tional calculations of the excited states of triclosan support the involvement of a radical intermedi

243 in P. aeruginosa shown to efficiently efflux triclosan, supporting the notion that efflux is the prim

244 ic domains, and its inhibition by drugs like triclosan (TCL) can increase cytotoxicity and decrease d

245 Triclosan (TCN) is a long-standing, proven antibacterial

246 Triclosan (TCS) and triclocarban (TCC) are antimicrobial

247 Removal of triclocarban (TCC) and triclosan (TCS) from wastewater is a function of adsorpt

248 Triclosan (TCS) is a broad-spectrum antimicrobial compou

249 Triclosan (TCS) is a synthetic antibacterial chemical wi

250 Triclosan (TCS) was treated under hydrothermal condition

251 Triclosan (TCS), a broad-spectrum antimicrobial, is used

252 Triclosan (TCS), a high volume chemical widely used in c

253 Triclosan (TCS), a high-production-volume chemical used

254 Triclosan (TCS), an antimicrobial chemical with potentia

255 of bisphenol A (BPA), benzophenone-3 (BP-3), triclosan (TCS), and parabens with serum total testoster

256 ), benzophenone-3 (BP-3), bisphenol A (BPA), triclosan (TCS), butyl paraben (B-PB), methyl paraben (M

257 Triclocarban (TCC) and triclosan (TCS), two of the most commonly used antimicro

258 LISA) for the detection of the antimicrobial triclosan (TCS; 2,4,4'-trichloro-2'-hydroxydiphenyl ethe

259 After dichotomizing SDQ scores, triclosan tended to be positively associated with emotio

260 ere with the formation of a stable FabI-NAD+-triclosan ternary complex acquire resistance to the drug

261 of bsFabI and formed a stable bsFabI.NAD(+).triclosan ternary complex.

262 he purified enzyme is much more resistant to triclosan than is E. coli FabI.

263 nto surface waters via wastewater effluents, triclosan, the antimicrobial agent in handsoaps, and chl

264 activity was NADH dependent and inhibited by triclosan; the residual activity in the fabI mutant was

265 ver weeks to months; children are exposed to triclosan through the use of some personal-care products

266 n of the slow-onset, tight-binding inhibitor triclosan to explore the interactions between the type I

267 tants to compare and contrast the binding of triclosan to InhA, the homologous enoyl reductase from M

268 Binding of triclosan to wild-type InhA is uncompetitive with respec

269 Triclosan toothpaste is effective in controlling plaque

270 Triclosan toothpaste led to a greater decrease in TC (P

271 These data suggest that triclosan toothpaste may influence some inflammatory bio

272 This triclosan transformation product was determined to have

273 two inhibitors having well-defined targets: triclosan (TRC), which inhibits InhA; and thiolactomycin

274 dations intended to prevent future harm from triclosan, triclocarban, and antimicrobial substances wi

275 stance genes and the antimicrobial chemicals triclosan, triclocarban, and methyl-, ethyl-, propyl-, a

276 of BASL4 overpredicted the concentrations of triclosan, triclocarban, and miconazole in root and shoo

277 DPU predicted concentrations of triclosan, triclocarban, miconazole, carbamazepine, and

278 Earlier research showing that triclosan underwent chlorine addition to form mono- and

279 trends were directly attributed to increased triclosan use, local improvements in treatment, and chan

280 ure to the synthetic antimicrobial chemical, triclosan, used in personal care products, has been hypo

281 Median maternal triclosan varied across pregnancy from 17 to 11 ng/mL, w

282 ch as pentachlorophenol, phenolic acids, and triclosan via surface-catalyzed oligomerization.

283 n), and the aOR per log(10) unit increase in triclosan was 1.2 (95% CI: 1.0, 1.4).

284 Triclosan was 66% (95% CI: 29-113) higher in 8 year olds

285 Triclosan was a slow-binding inhibitor of bsFabI and for

286 l in the MnOx(s) surface after reaction with triclosan was detected by XPS survey scans, while no Cl

287 losan, and its transformation product methyl triclosan was investigated after their uptake into carro

288 A fast metabolization of triclosan was observed and eight so far unknown phase II

289 Triclosan was positively associated with adiposity only

290 (2) reactivity only when a limited amount of triclosan was present.

291 Triclosan was used to inhibit specifically Block A, wher

292 Urinary concentrations of triclosan were measured in one first morning void from 6

293 a phenolic ring (parabens, bisphenol A, and triclosan) were completely transformed on this anode at

294 and 5-chloro-2-(2,4-dichlorophenoxy)phenol (triclosan)) were measured for 15 sorbents: fresh and car

295 is was associated with the highest levels of triclosan, whereas no association was seen for current a

296 was as sensitive as the wild-type strain to triclosan, whereas the ygaA knockout was 250-fold more s

297 berculosis drug isoniazid and the antiseptic triclosan, which are inhibitors of fatty acid biosynthes

298 Triclosan, which inhibits enoyl-ACP reductase (ENR), con

299 rd to the structure-activity relationship of triclosan while affording gains against cultured parasit

300 tuberculosis, show unimpaired inhibition by triclosan, with uncompetitive inhibition constants (K(i)