ライフサイエンスコーパス: triester

1 y between triaryl and dialkyl aryl phosphate triesters.

2 lexed diester and resembles the reactions of triesters.

3 s while slowing the rates of diesters and of triesters.

4 stability (tricarboxylate salt 1-CO(2)()Na > triester 1-CO(2)()Et > diester 2-CO(2)()Et > monoester 3

5 The AZT prodrug triesters, 1 and 2, underwent much more rapid hydrolysis

6 cines (+)-22 and (-)-23 and the cyclopropane triester (-)-26.

7 nderwent much more rapid hydrolysis than the triester 3, most probably due to the formation of an acy

8 Methylenation of the triester 3a and subsequent triple RCM reaction was follo

9 ing with an excess of olefin alcohol 1a gave triester 3a in excellent yield.

10 The synthesis of triester 7 involved reaction of alpha-(chloroacetyl)sali

11 However, potential prodrug triester 70 did induce enhancements in 2-deoxyglucose up

12 Pyromellitate triesters afforded the ortho diester anhydrides upon dis

13 te specificity for synthetic organophosphate triesters and phosphorofluoridates, which are common con

14 ein, we examine the propensities of PQQ, PQQ triester, and its various isomers, and certain PQQ tries

15 for the nonenzymatic hydrolysis of phosphate triesters, and is the inverse of that observed for the n

16 Organophosphate triesters are high production volume additive flame reta

17 class of phospholipids, alkyl phosphocholine triesters, are described.

18 ate degradation (opd) island, hydrolyzes the triester bond found in a variety of organophosphate inse

19 imized for the hydrolysis of organophosphate triesters can be made to catalyze the hydrolysis of orga

20 bonucleotide ('lariat') 25 by solution phase triester chemistry involving both H-phosphonate and conv

21 ingly high nucleophilic activity toward both triester DEDNPP and diester EDNPP.

22 er, and its various isomers, and certain PQQ triester derivatives, to catalyze glycine-fueled redox c

23 HA shows extraordinary reactivity toward the triester diethyl 2,4-dinitrophenyl phosphate (DEDNPP) an

24 thyl p-nitrophenyl phosphorothioate, and the triesters, diethyl p-nitrophenyl phosphate and diethyl p

25 n of pNPPT, the diester ethyl pNPPT, and the triester dimethyl pNPPT was probed using heavy atom kine

26 drolysis of the phosphorothioate diester and triester exhibits somewhat less advanced bond fission th

27 nker-derived amino group on the 3'-phosphate triester, followed by elimination of the desired product

28 beta-glycosyl phosphate and dithiophosphate triesters from glycals via 1,2-anhydrosugars.

29 ith a series of enantiomeric organophosphate triesters have shown that the wild type PTE generally pr

30 alkaline phosphatase (AP) is associative, or triester-like, because phosphorothioate monoesters are h

31 n rate strongly supporting the less accepted triester mechanism.

32 A triester method for the synthesis of deoxynucleoside pho

33 sters, symmetrical 6,6'-diesters, and 2,6,6'-triesters of fatty acids were calculated from the values

34 the corresponding dimethyl long-chain alkyl triesters of PFA.

35 zation in the presence of sorbitan mono- and triesters or canola oil was investigated.

36 The occurrence and fate of 14 triester organophosphate flame retardants (OPFRs) and pl

37 ction of O,O-diethyl 4-nitrophenyl phosphate triester (Paraxon, 1) with piperidine in ionic liquids (

38 five triaryl and two dialkyl aryl phosphate triesters, previously studied experimentally, is examine

39 of free nucleotides by the masked phosphate triester prodrugs.

40 Importantly, [3H]BZDC-triester-PtdIns(3,4,5)P3, the lipid with the same phosph

41 tion, consisting of perchlorotriphenylmethyl triester radical dissolved in hexafluorobenzene, for in

42 analogous phosphate monoester, diester, and triester reactions.

43 ing prevents accommodation of the additional triester substituent.

44 directly to the general base resulting in a triester (substrate as base) AN + DN mechanism with a mo

45 ajor effect on the corresponding reaction of triesters: though protonation of one nitrogen of DPP(-)

46 nosubstituted glucose residues in the 2,6,6'-triesters was altered considerably to favor the gt rotam

47 philicity of the methyl-substituted cycloSal triesters was performed based on the retention times obt

48 Refluxing orthoformate triesters were found to effect quantitative esterificati

49 Thus, different lipophilic triesters were prepared and characterized in oily soluti

50 The requisite triesters were prepared by selective saponification or b

51 Concentrations and patterns of 16 OP triesters were presently screened for and/or determined

52 the rate of hydrolysis of neutral phosphate triesters, where a methyl group has replaced a proton.

53 ansition states, in contrast to reactions of triesters, which have tight, associative transition stat

54 Reaction of the triesters with phosphorous pentachloride, followed by co

55 lective removal of one methyl group from the triesters with sodium iodide yielded monosodium salts, w

56 ucleotides rely on the reaction of phosphite triesters with sulfurizing reagents such as tetraethylth