ライフサイエンスコーパス: triphosphate

1 cleotidase that generates PPi from adenosine triphosphate.

2 d phosphatase for phosphatidylinositol 3,4,5-triphosphate.

3 corporation efficiency of the azide-modified triphosphate.

4 mpanied by a drop in intracellular adenosine triphosphate.

5 ng the cyclopropene-modified 2'-deoxyuridine triphosphate.

6 was directly inhibited by p-JNK + adenosine triphosphate.

7 ial metabolic pathways and produce adenosine triphosphate.

8 dative phosphorylation to generate adenosine triphosphate.

9 dily binds its analog guanosine 5'-3-O-(thio)triphosphate.

10 ates into component nucleoside and inorganic triphosphate.

11 NTPs into deoxyribonucleosides and inorganic triphosphate.

12 lecules, we employed (18)O-labeled adenosine triphosphate ((18)O-ATP) as the phosphate donor in a RIK

13 ryl group (2'-Az-dAMP) from the analogous 5'-triphosphate (2'-Az-dATP) onto the tyrosine hydroxyl gro

14 -associated genetic polymorphism in inositol-triphosphate 3-kinase C (ITPKC) (rs28493229) has importa

15 the parasite's sodium efflux pump (adenosine triphosphate 4).

16 his compound to the corresponding nucleoside triphosphate, 5-nitroindolyl-2'-deoxyriboside triphospha

17 This study showed that a 6-thioguanosine triphosphate (6-TGTP), converted in T-cells from 6-TP, t

18 l levels of 2'-deoxy-2'-spirooxetane uridine triphosphate (8), a potent inhibitor of the HCV NS5B pol

19 addition of guanosine-5'-[(beta,gamma)-imido]triphosphate, a poorly hydrolysable analog of GTP.

20 converting active Ras is bound to guanosine triphosphate, activating Ras into inactive Ras is bound

21 y in the context of elevated Cdc42-guanosine triphosphate activity, similar to nonmalignant, young HS

22 e dinucleotide redox potential and adenosine triphosphate/adenosine diphosphate failed to reach a new

23 case in complex with GTPgammaS, in which the triphosphate adopts a compact conformation in the absenc

24 The ParA-beta,gamma-imidoadenosine 5'-triphosphate (AMPPNP)-DNA structure revealed no polymers

25 2-as is able to use adenosine 5'-[gamma-thio]triphosphate analogs to thiophosphorylate its substrates

26 erase activity of a fluorescent cytidine TNA triphosphate analogue (1,3-diaza-2-oxo-phenothiazine, tC

27 g radiolabeled guanosine 5'-3-O-([(35)S]thio)triphosphate and [(3)H]ketanserin revealed that platelet

28 ed conversion of phosphatidylinositol(3,4,5)-triphosphate and accumulation of phosphatidylinositol(3,

29 ternatively makes UDP-galactose from uridine triphosphate and galactose-1-phosphate.

30 d biliary composition with reduced adenosine triphosphate and lysosomal enzyme release.

31 s to aldehydes using the cofactors adenosine triphosphate and nicotinamide adenine dinucleotide phosp

32 ry for hydrolysis of extracellular adenosine triphosphate and nicotinamide adenine dinucleotide, both

33 acetylcholine and a combination of adenosine triphosphate and nitric oxide, respectively.

34 Both Cdc42guanosine triphosphate and SNX9 activate N-WASP-WIP- and Arp2/3-me

35 raries specific for transcripts bearing a 5'-triphosphate and/or monophosphate revealed at least 63 p

36 In vitro, HpRppH converts RNA 5'-triphosphates and diphosphates to monophosphates.

37 imports the constituent unnatural nucleoside triphosphates and uses them to replicate DNA containing

38 ubated with lipopolysaccharide and adenosine triphosphate, and levels of IL1beta production were meas

39 rolysis of chemical fuels, such as adenosine triphosphate, and use the energy released to direct moti

40 nd 2"-deoxythymidine-5"-[(alpha, beta)-imido]triphosphate (approximating dT) at both the insertion an

41 alpha-(L)-threofuranosyl nucleic acid (TNA) triphosphates are selected and extended in a template-de

42 s nucleation of phosphatidylinositol (3,4,5)-triphosphate at the plasma membrane to enhance phosphoin

43 function, RecBCD unwinding at low adenosine triphosphate (ATP) (2-4 muM) was measured using an optic

44 cess is that PKA can hydrolysis adenosine-5'-triphosphate (ATP) and ALP can hydrolysis pyrophosphate,

45 ed the association of lithium with adenosine triphosphate (ATP) and identified a bimetallic (Mg.Li) A

46 nergic enzyme in the hydrolysis of adenosine triphosphate (ATP) and increased CD39 enzymatic activity

47 te method for the determination of adenosine triphosphate (ATP) and its first five catabolites: adeno

48 phosphate (NADP(+) and NADPH), and adenosine triphosphate (ATP) and its precursors, adenosine diphosp

49 neuropathological analysis and by Adenosine Triphosphate (ATP) and Phosphocreatine (PCr) levels.

50 that patients with BD show normal adenosine triphosphate (ATP) and phosphocreatine levels at rest bu

51 ll as an increase in intracellular adenosine triphosphate (ATP) and the accumulation of terminal syna

52 Extracellular adenosine triphosphate (ATP) binds as a danger signal to purinergi

53 y, protein synthesis activity, and adenosine triphosphate (ATP) biosynthesis pathways such as glycoly

54 atine, an organic acid involved in adenosine triphosphate (ATP) buffering, in oligodendrocyte functio

55 gy is extended to the detection of adenosine triphosphate (ATP) by aptamer recognition.

56 sulting in a highly CHK1 selective adenosine triphosphate (ATP) competitive inhibitor.

57 The PCr to adenosine triphosphate (ATP) concentration ratio (PCr/ATP) was sim

58 While, at low adenosine 5'-triphosphate (ATP) concentrations, motors did not genera

59 cells for essential nutrients and adenosine triphosphate (ATP) for a productive infection.

60 Here, we show that adenosine triphosphate (ATP) has properties of a biological hydrot

61 experimental data, we propose that adenosine triphosphate (ATP) hydrolysis by CglI produces transloca

62 ions using chemical energy from adenosine 5'-triphosphate (ATP) hydrolysis.

63 This process relies on adenosine triphosphate (ATP) hydrolysis.

64 ration of a target small molecule, adenosine triphosphate (ATP) in this work, in the range between 10

65 Adenosine triphosphate (ATP) induces pain via activation of ionotr

66 he proinflammatory "danger signal" adenosine triphosphate (ATP) is released from damaged cells and pr

67 tochondrial content, function, and adenosine triphosphate (ATP) levels, in conjunction with robust in

68 cillus thermarum, which hydrolyzes adenosine triphosphate (ATP) poorly.

69 ulation up-regulates mitochondrial adenosine triphosphate (ATP) production to fuel purinergic signali

70 EVs cause adenosine triphosphate (ATP) release from platelets and inflammaso

71 mechanical stability, and cellular adenosine triphosphate (ATP) release.

72 In contrast, transcripts of adenosine triphosphate (ATP) synthase and ribosomal protein genes

73 o treat tuberculosis has validated adenosine triphosphate (ATP) synthase as an attractive target to k

74 ur respiratory-chain complexes and adenosine triphosphate (ATP) synthase.

75 : Mitochondrial O2 consumption and adenosine triphosphate (ATP) synthesis rates of osteosarcoma cybri

76 lectron transport chain capable of adenosine triphosphate (ATP) synthesis, combining Escherichia coli

77 ose deprivation and contained less adenosine triphosphate (ATP) than WT nerves.

78 monstrated that in the presence of adenosine triphosphate (ATP) the human RAD51 (HsRAD51) recombinase

79 ic lock to prevent coordination of adenosine triphosphate (ATP) to the catalytic site.

80 derpinning molecular mechanisms of adenosine triphosphate (ATP) utilisation.

81 Extracellular adenosine triphosphate (ATP), a potent danger molecule, is elevate

82 PH); coenzymes of energy including adenosine triphosphate (ATP), adenosine diphosphate (ADP), and ade

83 In the presence of adenosine triphosphate (ATP), all three components bind in a 1:1 s

84 cal gradients or the hydrolysis of adenosine triphosphate (ATP), so far there are no synthetic small-

85 sodilators acetylcholine (ACh) and adenosine triphosphate (ATP), the endothelium-independent vasodila

86 cations such as the measurement of adenosine triphosphate (ATP), the energy unit in biological system

87 ABCB4 (MDR3) is an adenosine triphosphate (ATP)-binding cassette (ABC) transporter ex

88 ng disease-causing variants in the adenosine triphosphate (ATP)-binding cassette subfamily A member 4

89 d onto DNA directly interacts with adenosine triphosphate (ATP)-bound DnaA and stimulates the hydroly

90 In contrast, Tregs devoid of the adenosine triphosphate (ATP)-degrading ecto-enzyme CD39 were unabl

91 the chromatin landscape shaped by adenosine triphosphate (ATP)-dependent chromatin remodeling and tr

92 Adenosine 5'-triphosphate (ATP)-dependent chromatin remodeling enzyme

93 were only known to participate in adenosine triphosphate (ATP)-dependent proteolysis in bacteria.

94 ies also include duplex annealing, adenosine triphosphate (ATP)-dependent RNA binding, and RNA-protei

95 H2O2 dose-dependently impaired the adenosine triphosphate (ATP)-induced Ca(2+) response, which was pa

96 channel activated by extracellular adenosine triphosphate (ATP).

97 he Mtb proteasome independently of adenosine triphosphate (ATP).

98 etamine tended to downregulate the adenosine triphosphate (ATP)/adenosine diphosphate (ADP) metabolit

99 verting a chosen biological input, adenosine triphosphate (ATP; that does not directly bind to the CB

100 ctrometry for energetic cofactors (adenosine triphosphate [ATP]/adenosine diphosphate [ADP]/adenosine

101 enzimidazole-derived 2'-deoxynucleoside-5'-O-triphosphates ( BENZI: TP and BIM: TP) by an engineered

102 naling events such as guanosine 5'-3-O-(thio)triphosphate binding and beta-arrestin2 recruitment.

103 In guanosine 5'-3-O-(thio)triphosphate binding and INS1 832-3 insulinoma cell cAMP

104 This mutation impairs adenosine triphosphate binding and reduces catalytic activity.

105 a the sterol-exporting heterodimer adenosine triphosphate binding cassette subfamily G member 5/8 (AB

106 elity variants also show that changes in the triphosphate binding environment are not always accompan

107 erotrimeric G protein guanosine 5'-3-O-(thio)triphosphate binding reconstitution assays.

108 Ibrutinib and A419259 also blocked adenosine triphosphate binding to HCK, whereas transduction of mut

109 The adenosine triphosphate-binding cassette (ABC) sterol transporter,

110 racterization of a Petunia hybrida adenosine triphosphate-binding cassette (ABC) transporter, PhABCG1

111 rol efflux via the upregulation of adenosine triphosphate-binding cassette (ABC) transporters, ABCA1

112 the Gardos channel; and ABCB6, an adenosine triphosphate-binding cassette family member, in the main

113 nsport activity of P-glycoprotein (adenosine triphosphate-binding cassette subfamily B, member 1 [ABC

114 breast cancer resistance protein (adenosine triphosphate-binding cassette subfamily G, member 2 [ABC

115 uence of a Clostridium perfringens adenosine triphosphate-binding cassette transporter.

116 focusing on their highly conserved adenosine triphosphate-binding domain.

117 NRAS is a guanosine triphosphate-binding protein whose most well-characteriz

118 containing biotinlated 2'-deoxyadenosine 5'-triphosphate (biotin-dATP) by terminal deoxynucleotidyl

119 or, at most, a few biotin-labeled nucleotide triphosphates (biotin-NTPs) into the 3' end of nascent R

120 mistry and Transferase-mediated deoxyuridine triphosphate-biotin nick end labelling (TUNEL), was perf

121 fluorescence of BODIPY-conjugated adenosine triphosphate (BODIPY-ATP) was quenched by Fe(III) ions t

122 etween the 5'-C of ATP and the oxygen of the triphosphate (bond order of 0.23).

123 Sperm motility is powered by adenosine triphosphate but the relative importance of lactate ferm

124 -diphosphate, and phosphatidylinositol 3,4,5-triphosphate) but do not bind to 100% phosphatidylcholin

125 tivated antimetabolite, 2'3'-dideoxycytidine triphosphate by cytoplasmic nucleoside kinases.

126 tions at residues known to interact with the triphosphate can alter the binding orientation/environme

127 hesis via assembly of the 7-methyl-guanosine triphosphate cap-dependent translation complex.

128 in mitochondria of trypanosomes maintain 5' triphosphate characteristic of the transcription initiat

129 NK2 or treatment with JNK-IN-8, an adenosine triphosphate-competitive irreversible pan-JNK inhibitor,

130 assembled DNA polymerase-DNA-deoxynucleoside triphosphate complex with two canonical metal ions bound

131 de with two peaks of intracellular adenosine triphosphate concentration.

132 pterin (BH4) biosynthetic enzymes (guanosine triphosphate cyclohydrolase-1 and dihydrofolate reductas

133 The triphosphates dA(SR)TP were good substrates for DNA poly

134 es were converted to 5'-O-mono-(dA(SR)MP) or triphosphates (dA(SR)TP) by phosphorylation.

135 nhance the intrinsic levels of deoxycytidine triphosphate (dCTP).

136 Adenosine triphosphate-dependent chromatin remodeling machines pla

137 through the helicase domain in an adenosine triphosphate-dependent manner.

138 endent termination relies upon the adenosine triphosphate-dependent RNA translocase Rho, which binds

139 ts transport activity, assessed by adenosine triphosphate-dependent taurocholate transport in canalic

140 UVA-induced mitochondrial damage, adenosine triphosphate depletion, and the ensuing necrotic cell de

141 a leads to necrotic cell death via adenosine triphosphate depletion.

142 ophosphate transporter, leading to adenosine triphosphate depletion.

143 Ectonucleoside triphosphate diphosphohydrolase 1 (NTPDase1) degrades th

144 d cancer cells, we identified ectonucleoside triphosphate diphosphohydrolase 5 (ENTPD5) as a mutant p

145 well as the ectonucleotidases ectonucleoside triphosphate diphosphohydrolase [ENTPD; cluster of diffe

146 Ectonucleoside triphosphate diphosphohydrolase-1 (CD39), an enzyme expr

147 her reduce RT-mediated incorporation of NRTI triphosphates (discrimination mechanism) or confer an AT

148 A primer duplex and incoming deoxynucleotide triphosphate (dNTP) at 3.0-A resolution.

149 , and Ca(2+), which supports deoxynucleoside triphosphate (dNTP) binding but not catalysis.

150 L1 deletion, which increases deoxynucleoside triphosphate (dNTP) pools.

151 SAMHD1 is a deoxynucleoside triphosphate (dNTP) triphosphohydrolase that cleaves phy

152 ror with the appropriate deoxyribonucleoside triphosphate (dNTP).

153 xyribonucleoside triphosphate/ribonucleoside triphosphate (dNTP/rNTP) ratios, by the ability of DNA p

154 creasing the availability of deoxynucleoside triphosphates (dNTP) and thus HIV-1 reverse transcriptio

155 ism of canonical and noncanonical nucleoside triphosphates (dNTPs) and has been associated with cance

156 Deoxynucleotide triphosphates (dNTPs) are essential for efficient hepati

157 ounts of DNA precursors (deoxyribonucleoside triphosphates (dNTPs)).

158 e to limited availability of deoxynucleoside triphosphates (dNTPs), which are needed for HIV-1 revers

159 DNA replication requires deoxyribonucleotide triphosphates (dNTPs).

160 ion of canonical and noncanonical nucleotide triphosphates (dNTPs).

161 olymerases against 2'-deoxyribonucleoside 5'-triphosphates (dNTPs).

162 of de novo synthesis of deoxyribonucleotide triphosphates (dNTPs).

163 on of innate immunity is independent of a 5' triphosphate, double-stranded RNA structure, or the prim

164 iven presequence translocation and adenosine triphosphate-driven import motor activity.

165 group of the native substrate with adenosine triphosphate, enabling sensitive detection via luciferas

166 the presence of (th) G and native nucleoside triphosphates enforces initiation with the unnatural ana

167 rted to nucleoside 2'-phosphoramidites or 3'-triphosphates for solid-phase and polymerase-mediated sy

168 Phosphoramidate 16 in its 5'-triphosphate form specifically inhibited HCV NS5B polyme

169 tructures of hPolbeta, DNA and L-dCTP or the triphosphate forms of antiviral drugs lamivudine ((-)3TC

170 liver facilitating the release of adenosine triphosphate from hepatocytes.

171 tricornutum, imports the requisite unnatural triphosphates from its medium and then uses them to repl

172 ofovir diphosphate [TFVdp] and emtricitabine triphosphate [FTCtp], respectively), and competing endog

173 ion and pinpoint why the TS for guanosine 5'-triphosphate (GTP) hydrolysis is higher in energy when R

174 kinase (RTK) ligands increase RhoA-guanosine triphosphate (GTP) in untransformed and transformed cell

175 Here, we find that the binding of guanosine triphosphate (GTP) to one subunit inhibits the binding a

176 that catalyze the hydrolysis of guanosine 5'-triphosphate (GTP) to promote conformational changes.

177 lability of ATP, which regenerates guanosine triphosphate (GTP), powers ribosomes, and promotes trans

178 demonstrate that TBSV co-opts the guanosine triphosphate (GTP)-bound active form of the endosomal Ra

179 e formation increased the level of guanosine triphosphate (GTP)-bound ARF1.

180 endent, but neither palmitoyl- nor guanosine triphosphate (GTP)-dependent, fashion.

181 hing residues, and catalysis make nucleoside triphosphate hydrolysis conditional on domain movement,

182 ines a sequential, around-the-ring adenosine triphosphate hydrolysis cycle that results in stepwise s

183 s two distinct folds, and the post-adenosine triphosphate hydrolysis state of KaiC create a hub aroun

184 in is a molecular motor capable of adenosine triphosphate hydrolysis-dependent translocation along do

185 egation events by stimulating ParF adenosine triphosphate hydrolysis.

186 o a 3-dimentional printed resorbable calcium-triphosphate/hydroxyapatite scaffold implanted in a calv

187 evaluate the role of extracellular adenosine triphosphate in ischemic injury in specific organs, in o

188 oduction by lipopolysaccharide and adenosine triphosphate in PBMCs.

189 ls were suppressed; also levels of adenosine triphosphate in the intestine of animals with moderate a

190 is to facilitate the production of adenosine triphosphate in the mitochondria by participating in red

191 sed the productions of lactate and adenosine triphosphate in tumor cells and in the Ras-transformed m

192 h ratio of ribonucleotide to deoxynucleotide triphosphates in tissues, and that riboadenosines accoun

193 riphosphate, 5-nitroindolyl-2'-deoxyriboside triphosphate, in vivo creates a potent inhibitor of seve

194 nt increase in the potency of inositol 1,4,5-triphosphate-induced Ca(2+) signaling underlies LTP faci

195 ted eukaryotic initiation factor 2-guanosine triphosphate-initiator methionyl transfer RNA (eIF2.GTP.

196 ses the rate constant for deoxynucleoside 5'-triphosphate insertion compared to magnesium.

197 e that specifically degrades deoxynucleoside triphosphates into component nucleoside and inorganic tr

198 An inositol 1,4,5-triphosphate (IP3) receptor inhibitor prevented the indu

199 ivity that occurs in the absence of inositol triphosphate (IP3)-dependent release from endoplasmic re

200 Within the liver vasculature, adenosine triphosphate is converted into pyrophosphate, a major in

201 to show that the binding environment of the triphosphate is different when correct versus incorrect

202 d with fluorescein isothiocyanate-uridine 5'-triphosphate labeling, RNA fluorescence in situ hybridiz

203 ence of RecQ helicase and saturating adenine triphosphate let us deduce that RecQ binds to ssDNA via

204 The adenosine triphosphate level of the cell is predictive of bacteric

205 SRT1720 treatment increased adenosine triphosphate levels and survival of cultured hepatocytes

206 er agent alone, slightly decreased adenosine triphosphate levels in AR42J cells, but induced oxidativ

207 enhanced autophagy, and preserved adenosine triphosphate levels in the liver after ischemia-reperfus

208 on for analyses of hepatic injury, adenosine triphosphate levels, mitochondrial mass, autophagy, infl

209 gellar motility and an increase in adenosine triphosphate levels.

210 They act nonredundantly to produce inositol triphosphate-mediated intracellular Ca(2+) flux and LFA-

211 ss the molecular mechanisms behind adenosine triphosphate-mediated ischemic tissue injury and evaluat

212 is converted into its therapeutically active triphosphate metabolite, Ara-CTP, which exerts antileuke

213 egulation by magnesium (Mg) and Mg.adenosine triphosphate (Mg.ATP).

214 e substrate analog 2',3'-dideoxyguanosine-5'-triphosphate, MnCl2, and tartrate, but their quaternary

215 reveals the functional interplay between NTP triphosphate moiety and base pair hydrogen bonding recog

216 However, how the triphosphate moiety of substrate influences the rate of

217 a common underlying extracellular adenosine triphosphate molecular mechanism in ischemic organ injur

218 Adenosine triphosphate molecule has been implicated in various isc

219 N(2) -Alkyl-2'-deoxyguanosine triphosphate (N(2) -alkyl-dGTP) derivatives with methyl,

220 nucleotide transferase-mediated deoxyuridine triphosphate nick end-labeling (TUNEL)-positive cells an

221 ucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling (TUNEL) histology.

222 reduction of serum transaminases, bilirubin, triphosphate nick-end labeling staining, caspase-3 activ

223 antly at physiologically relevant nucleoside triphosphate (NTP) concentrations.

224 The pharmacologically active nucleoside triphosphate (NTP) is efficiently formed in multiple hum

225 to select and incorporate correct nucleoside triphosphate (NTP) substrates with high efficiency and f

226 optosis was increased by HERV-K deoxyuridine triphosphate nucleotidohydrolase in an interleukin 6-ind

227 , 3 weekly injections of HERV-K deoxyuridine triphosphate nucleotidohydrolase induced hemodynamic and

228 HERV-K deoxyuridine triphosphate nucleotidohydrolase induced SAMHD1 and proi

229 HERV-K envelope and deoxyuridine triphosphate nucleotidohydrolase mRNAs were elevated in

230 Departure of the leaving group triphosphate of ATP is well advanced and forms a 2.32 A

231 For example, converting the 5'-terminal triphosphate of bacterial transcripts to a monophosphate

232 tic mRNAs, the conversion of the 5'-terminal triphosphate of bacterial transcripts to a monophosphate

233 ults demonstrate that DUSP11 converts the 5' triphosphate of miRNA precursors to a 5' monophosphate,

234 a template-primer involving the terminal 5'-triphosphate of RNA and the 3'-overhang of DNA results i

235 at the viperin substrate may be a nucleoside triphosphate of some type.

236 ggested that there is a reorientation of the triphosphate of the incoming nucleotide, which is essent

237 Four triphosphates of 2'-deoxyuridine that carried the follow

238 Here, by using the triphosphates of chain-terminating antiviral drugs lamiv

239 and 2'-deoxythymidine-5'-[(alpha,beta)-imido]triphosphate opposite the 5'-A, the 3'-terminal nucleosi

240 Nucleoside triphosphate phosphohydrolase I (NPH I) is an essential

241 interaction of CD81 with the deoxynucleoside triphosphate phosphohydrolase SAMHD1.

242 l enrichment of phosphatidylinositol (3,4,5)-triphosphate (PIP3) within the spine plasma membrane.

243 RNAs with 5'-triphosphate (ppp) are detected in the cytoplasm princip

244 ended double-stranded (ds)RNAs carrying a 5' triphosphate (ppp) moiety.

245 ory deficiency lowed mitochondrial adenosine triphosphate production and increased the production of

246 1.5-fold increase in mitochondrial adenosine triphosphate production and were less prone to mitochond

247 ponsible for energy conversion and adenosine triphosphate production in eukaryotic cells.

248 Although diminished mitochondrial adenosine triphosphate production is recognized as a source of pat

249 mitochondrial membrane potential, adenosine triphosphate production, and reactive oxygen species gen

250 he thylakoid membrane and elevated adenosine triphosphate production.

251 are associated with CDC42, a small guanosine triphosphate protein linked to T-cell activation.

252 oduction by lipopolysaccharide and adenosine triphosphate (R(2) = .88).

253 d by karyopherins (Kaps) and a Ran guanosine triphosphate (RanGTP) gradient that imports nuclear loca

254 etic status (phosphocreatine/gamma-adenosine triphosphate ratio, 1.3+/-0.1 versus 1.9+/-0.1, P<0.001)

255 ATPase (SERCA) pump and blockers of inositol triphosphate receptor (InsP3 R) and ryanodine receptor (

256 n autophagy by activation of type 1 inositol triphosphate receptor (InsP3R-1).

257 culum Ca-ATPase (SERCA) pump, inositol-1,4,5-triphosphate receptor (IP3R), and Ryanodine receptor (Ry

258 d protein 75), and the IP3R1 (inositol-1,4,5-triphosphate receptor 1), leading to mitochondrial Ca(2+

259 vations during PIDs are mediated by inositol triphosphate receptor type 2-dependent (IP3R2-dependent)

260 rombopoiesis and an abrogated inositol 1,4,5-triphosphate receptor-dependent intracellular calcium (C

261 both ryanodine receptors (RyRs) and inositol triphosphate receptors (InsP3 Rs).

262 for these responses included inositol 1,3,5-triphosphate receptors, PKC, and enhancement of filament

263 ated impairments in red blood cell adenosine triphosphate release and stimulation of endothelium-depe

264 red that absence of ABCC6-mediated adenosine triphosphate release from the liver and consequently red

265 hanges in motifs B and D, and the nucleoside triphosphate reorientation represent separable, "tunable

266 ITPR1 encodes an inositol 1,4,5-triphosphate-responsive calcium channel.

267 ation of adenine moiety in (deoxy)nucleoside triphosphates, resulting in formation of (d)ITP, can be

268 in DNA is determined by deoxyribonucleoside triphosphate/ribonucleoside triphosphate (dNTP/rNTP) rat

269 Extracellular adenosine triphosphate rises in blood and bile after PH and contri

270 compared different adjuvants and identified triphosphate RNA (3pRNA) as especially effective at indu

271 ymerases discriminate against ribonucleotide triphosphate (rNTP) incorporation very effectively, the

272 d the balance of dNTPs and ribonucleoside 5'-triphosphates (rNTPs) in the cellular pool, with signifi

273 NA polymerases misincorporate ribonucleoside triphosphates (rNTPs) into DNA approximately once every

274 esis with reversibly terminated deoxyinosine triphosphates (rtITP).

275 of P and formally demonstrate that ribavirin triphosphate (RTP) inhibits the RdRP.

276 y impairs platelet aggregation and adenosine triphosphate secretion induced by numerous agonists (col

277 Addition of a 5'-triphosphate slightly enhances binding affinity.

278 conferring protein at lysine-70 in adenosine triphosphate synthase complex promoted its interaction w

279 to its corresponding enantiomeric nucleotide triphosphate, this study sets the stage for further bioc

280 o(2-methyl)imidazolides (2-MeImptNs), and 3'-triphosphates (tNTPs) bearing the four genetic bases of

281 cells were incubated with LPS and adenosine triphosphate to activate the NLRP3 complex.

282 le of catalyzing the conversion of guanosine triphosphate to cGMP.

283 , like Ded1p, utilizes exclusively adenosine triphosphates to unwind helices, oligomerizes to functio

284 We conclude that triphosphate-to-monophosphate conversion to induce 5' en

285 erichia coli that, by virtue of a nucleoside triphosphate transporter from Phaeodactylum tricornutum,

286 ng protein 1 (SAMHD1), a deoxyribonucleoside triphosphate triphosphohydrolase that decreases dNTP poo

287 The global regulation of nucleotide triphosphate turnover by intracellular Mg(2+) availabili

288 nucleotides such as ATP, ADP, and uridine 5'-triphosphate (UTP), among others, may serve as extracell

289 ein-coupled receptor activated by uridine-5'-triphosphate (UTP), which is widely expressed in the bod

290 he role of hydrocortisone (HC) on uridine-5'-triphosphate (UTP)-stimulated ion transport in different

291 eukin-1beta and interleukin-6) and adenosine triphosphate were also measured.

292 The modified triphosphates were also prepared by thiol addition to 7-

293 The modified nucleoside triphosphates were good substrates for DNA polymerases a

294 tosine 2'-deoxyribonucleosides and mono- and triphosphates were synthesized through aqueous Suzuki-Mi

295 ed the level of phosphatidylinositol (3,4,5)-triphosphate, which transactivates the Akt/mammalian tar

296 rt limited by the stability of the unnatural triphosphates, which are degraded by cellular and secret

297 nstead hydrolyze nucleoside diphosphates and triphosphates, which may play a role in purinergic signa

298 ctions with inverse electron demand, and one triphosphate with a tetrazole core was designed for the

299 Two triphosphates with tetrazines and one with a cyclopropen

300 rt the synthesis and evaluation of unnatural triphosphates with their beta,gamma-bridging oxygen repl