ライフサイエンスコーパス: trisaccharide

1 n blastose in 43.2% molar yield based on the trisaccharide.

2 in the assembly of a protected S. pneumoniae trisaccharide.

3 protein and with one repeat of the terminal trisaccharide.

4 ing-end mannoses are different from the free trisaccharide.

5 activity reduced the prevalence of the O-Fuc trisaccharide.

6 unsymmetrical urea-linked disaccharides and trisaccharide.

7 e to initiate construction of the side-chain trisaccharide.

8 in concurrence with the lowest K(m) for the trisaccharide.

9 (Gal) and 3 (GlcNAc, GalNAc) of the terminal trisaccharide.

10 nity binding to glycans bearing the Lewis(x) trisaccharide.

11 d core structure and a nonrepeating terminal trisaccharide.

12 oluble in diethyl ether, because of the free trisaccharide.

13 f this glycopeptide with an N-bromoacetamido trisaccharide.

14 1,3Galbeta1,4GlcNAc; and the type B branched trisaccharide.

15 ted form of O-linked glucose appears to be a trisaccharide.

16 aining a terminal sialyl N-acetyllactosamine trisaccharide.

17 mono-cultures grew very efficiently on this trisaccharide.

18 l bromide, gave exclusively the alpha-linked trisaccharide.

19 hydrophobic cleft interacting with the core trisaccharide.

20 d pentasaccharide that contains the Lewis(x) trisaccharide.

21 is exemplified in the one-pot synthesis of a trisaccharide.

22 al domain N of the lyase was found to bind a trisaccharide.

23 ansferase2 (B3GALNT2) to form the O-mannosyl trisaccharide.

24 ing may require engagement of more than four trisaccharides.

25 one-pot syntheses of chondroitin and heparin trisaccharides.

26 a block route involving the coupling of two trisaccharides.

27 lycosyl fluoride donors to yield the derived trisaccharides.

28 ccharides were short (Ser/Thr)-GalNAc-Gal-SA trisaccharides.

29 oxin serotype A when expressed as individual trisaccharides.

30 of the TES ether of disaccharide 16a, while trisaccharide 18a results from a glycosidation of in sit

31 Trisaccharide 2 is a derivative of 1, in which the hydro

32 ts 3-deoxy-D-manno-2-octulosonic acid) and a trisaccharide (2) having the structure alpha-D-GalpA-(1-

33 f 20 and a 43:27:30 mixture of regioisomeric trisaccharides 29 and 30 and tetrasaccharide 31 from the

34 ing domain for fucose (460 muM) and H type 2 trisaccharide (390 muM), an HBGA shown previously to be

35 same GalNAc-4-SO4- and GalNAc-3-SO4-bearing trisaccharides (6.7 mol of trisaccharide/mol of bovine s

36 ATCC 10543 capable of liberating both the A trisaccharide (A-Tri; GalNAcalpha1-->3(Fucalpha1-->2)Gal

37 ed more challenging, particularly with bulky trisaccharide acceptors.

38 GlcpNAc(1 -->3)]alpha-L-Rhap or the branched trisaccharide alpha-L-Rhap(1-->2)[beta-D-GlcpNAc(1-->3)]

39 iselase digestion of the products released a trisaccharide (alpha-[(3)H]xylosyl-isoprimeverose), indi

40 O-), di- (beta-Gal-1,3-alpha-GalNAc-O-), and trisaccharide (alpha-Fuc-1,2-beta-Gal-1,3-alpha-GalNAc-O

41 The di- and trisaccharide analogues were found to be slightly less e

42 near rhamnose-containing oligosaccharides, a trisaccharide and a pentasaccharide.

43 tuted at position 3 with an arabinose di- or trisaccharide and at position 6 with glucuronic acid or

44 abilized by several interactions between the trisaccharide and CD1d residues.

45 ctures of the NV P domain with and without A trisaccharide and the NV P polypeptide revealed no major

46 he synthetic ligand, relative to the natural trisaccharide, and that the entropic component does not

47 etic efforts also provided a reduced phospho-trisaccharide, and the NMR data of this derivative confi

48 ose), the universal fucosyl donor, the Le(x) trisaccharide, and their C-5 substituted derivatives can

49 e adducts of monosaccharides, disaccharides, trisaccharides, and heptasaccharides were separated on a

50 assing hexoses, pentoses, disaccharides, and trisaccharides, and is able to oxidize glucose to glucon

51 f germ-line residues to recognize the entire trisaccharide antigen and so confer strict specificity.

52 mplex with the Chlamydiaceae family-specific trisaccharide antigen Kdo(2-->8)Kdo(2-->4)Kdo (Kdo = 3-d

53 erance to GM3, an important tumor-associated trisaccharide antigen, seriously hinders its usage in ca

54 lera toxin subunit B, R-phycoerythrin, and B-trisaccharide antigen, with dissociation constants up to

55 d strict specificity for the family-specific trisaccharide antigen; however, only the related antibod

56 (Sp3GH98), which cleaves the entire terminal trisaccharide antigenic determinants of both A- and B-an

57 Data from synthetic trisaccharide antigens 2 and 3 and tetrasaccharide antig

58 stacked" conformation known for the isolated trisaccharide antigens.

59 Galactose alpha1-3 galactose (Gal) trisaccharides are present on the surface of wild-type p

60 approximately 4 ion pairs for the reference trisaccharide, are formed in the interaction.

61 idase sensitivity defined a novel glucuronyl trisaccharide as GlcNAcbeta1-3(GlcAbeta1-4)fucitol.

62 f the additional sugar-MBP interactions in a trisaccharide as opposed to a monosaccharide are offset

63 peat covalently modified by a full O-glucose trisaccharide at 2.2 A resolution.

64 complex with the pentasaccharide and various trisaccharides at 1.9-2.0A resolution showed that beta4G

65 20 CBMs was synthesized with mono-, di-, or trisaccharides at each site for comparison of binding af

66 binant Glt1 strongly preferred the full core trisaccharide attached to Skp1 and labeled only Skp1 in

67 i; GalNAcalpha1-->3(Fucalpha1-->2)Gal) and B trisaccharide (B-Tri; Galalpha1-->3(Fucalpha1-->2)Gal) f

68 olecules differ, containing either a complex trisaccharide (B. pertussis), a trisaccharide plus an O-

69 f a repeating unit consisting of a HexNAc(3) trisaccharide backbone in which two of the three HexNAc

70 2, the disaccharide beta-maltose, 3, and the trisaccharide beta-maltotriose, 4) were synthesized, pur

71 njugated to the fungal cell wall beta-mannan trisaccharide [beta-(Man)(3)] by novel saccharide-peptid

72 Glycopeptide 1 with the fucosylated trisaccharide, beta-d-GlcNAc(1-->4)[alpha-l-Fuc(1-->6)]-

73 These three features favorable to trisaccharide binding are consistent with the observatio

74 The A-trisaccharide binding mode seen in the NV P domain compl

75 2.3-A cocrystal structure reveals that the A trisaccharide binds to the NV P domain through interacti

76 pocket, unlike in the structures of A and B trisaccharides bound to VA387 P domain, where the alpha-

77 inoglycoside antibiotic isepamicin, a psuedo-trisaccharide, bound to aminoglycoside nucleotidyltransf

78 re employed for the assembly of the L-rhamno-trisaccharide building block.

79 glucose moiety was converted into a di- and trisaccharide by following the protection and deprotecti

80 d but not alpha/beta-(1-->3)-linked glucosyl trisaccharides can be bound by their internal glucosyl r

81 nthracycline subgroup that contains a C(7)-O-trisaccharide chain composed of L-2-deoxysugars.

82 analogue with a modified or even incomplete trisaccharide chain.

83 N-Glycopeptides containing 1 to 4 trisaccharide chains, with the carbohydrates vicinal to

84 previously reported for the VA387 P-domain-A-trisaccharide complex.

85 t a minimum binding sequence is a disulfated trisaccharide comprised of an internal iduronate flanked

86 y, incubation of T3SA+ with sialyllactose, a trisaccharide comprised of lactose and sialic acid, bloc

87 s with conjugates containing disaccharide or trisaccharide conjugated to immunogenic proteins followe

88 with a six-membered lactone) and digoxin (a trisaccharide-conjugated CTS with a five-membered lacton

89 5 capsular polysaccharide repeating unit, a trisaccharide consisting of two FucNAc units, is describ

90 f many Gram-negative bacteria is composed of trisaccharides containing 4-O-phosphorylated L-glycero-D

91 ofuranosidase capable of hydrolyzing di- and trisaccharides containing a terminal, non-reducing fruct

92 es in a single glucose attached to a heptose trisaccharide core and 2-keto-3-deoxyoctulosonic acid.

93 kes an LOS that consists only of the heptose trisaccharide core and 2-keto-deoxyoctulosonic acid (KDO

94 sugar moieties extending beyond the heptose trisaccharide core is not required for pustule formation

95 ccessfully utilized for the synthesis of the trisaccharide core of complex N-linked glycans.

96 1,6-arm mannose residues generates a linear trisaccharide core structure and resulted in a significa

97 noethyl glycosides of selectively O-sulfated trisaccharide corresponding to the HNK-1 antigen, its no

98 s two-step activation, trans-trans-patterned trisaccharides could be assembled in a highly efficient

99 mer of the H-type II blood group determinant trisaccharide (D-Fuc-(alpha1-->2)-L-Gal-(beta1-->4)-L-Gl

100 ely 10.7 microM) comparable to the reference trisaccharide DEF ( approximately 4.5 microM), it accele

101 haride DEFGH was previously shown to involve trisaccharide DEF first binding and inducing activation

102 cent to the binding domain for the reference trisaccharide DEF.

103 geometry and interaction profile for ECS and trisaccharide DEF.

104 the (1-->5)-beta-d-galactofuranosyl di- and trisaccharide derivatives 12 and 13.

105 , a variety of selectively protected di- and trisaccharide derivatives can be accessed in an operatio

106 s were applied to the synthesis of a Lewis X trisaccharide displaying a propargyl group at the anomer

107 We found that the entire branched trisaccharide domain of QS-21 is dispensable for adjuvan

108 rough derivatizing at the west wing branched trisaccharide domain.

109 ycosylation procedures, and a novel Lewis(x) trisaccharide donor, 7, was prepared and utilized as a k

110 odipeptide, a 6-deoxy-L-talosyl dipeptide, a trisaccharide donor, and a 3-hydroxyalkanoic acid.

111 eation of the glycosidic linkage between the trisaccharide donor, used as a pentenyl glycoside, and t

112 ome egg antigens, which contain the Lewis(x) trisaccharide, drive alternative activation of APCs and

113 tic immmunoaffinity columns, the immobilized trisaccharide (DSG-Sepharose) eliminates anti-GQ1b antib

114 This antibody optimally binds di- and trisaccharide epitopes, whereas larger oligomers bind wi

115 ride and low levels of a fully reconstituted trisaccharide form of aclacinomycin are observed.

116 [(3)H]glucose from UDP-[(3)H]glucose to the trisaccharide form of Skp1 in a glt1-dependent fashion.

117 sulfur analogues of derivatives of branched trisaccharides found in natural polysaccharides.

118 hrough either an alpha- or beta-linkage to a trisaccharide fragment of mycobacterial arabinan.

119 y occurring carbohydrate motifs, including a trisaccharide fragment of the naturally occurring marine

120 ed, spacer-equipped, phosphorylated upstream trisaccharide fragment of the O-PS of V. cholerae O139.

121 entasaccharides, two tetrasaccharides, and a trisaccharide fragment of the O-specific antigen of Vibr

122 exasaccharides, the Le(x) and Le(a) branched trisaccharide fragments adopt the rigid "stacked" confor

123 The conformational properties of di- and trisaccharide fragments of the polysialic acid O-antigen

124 production of singly charged mono-, di-, and trisaccharide fragments.

125 lex, VLR RBC36 in complex with the H-antigen trisaccharide from human blood type O erythrocytes, at 1

126 ycosyltransferase reactions to build di- and trisaccharides from the virus surface.

127 ctions of residual dipolar couplings for the trisaccharide fucosyllactose.

128 cid (UDP-GlcUA) to the common linkage region trisaccharide Gal beta 1-3Gal beta 1-4Xyl covalently bou

129 and leukocytes, and to the Gal alpha 1-3Gal trisaccharide (Gal) antigen.

130 The trisaccharide, Gal beta 4GlcNAc beta 3Fuc, is the minima

131 The fucose moiety of the blood group B trisaccharide Galalpha1-3(Fucalpha1-2)Gal also binds to

132 define the binding epitope for BDCA-2 as the trisaccharide Galbeta1-3/4GlcNAcbeta1-2Man.

133 ted that this adhesin specifically binds the trisaccharide Galbeta1-4(Fucalpha1-3)GlcNAc, also known

134 sing monovalent and multivalent forms of the trisaccharide GalNAcbeta1,4GlcNAcbeta1,2Manalpha (GGnM)

135 Hep4P and Hep-(1-->7)-Hep4P and the branched trisaccharide Glc-(1-->3)-[Hep-(1-->7)]-Hep4P, respectiv

136 A GlcNAc-capped trisaccharide, GlcNAc beta 1,4GlcNAc beta 1,4GlcNAc,was

137 analpha1,3-Manbeta-OR (1,4-1,3-arm); and the trisaccharide GlcNAcbeta1,4-GlcNAcbeta1,4-GlcNAc (chitot

138 (GlcNAcbeta1,2-Manalpha1,3)Man; the 1,6-arm trisaccharide, GlcNAcbeta1,2-Manalpha1,6-Manbeta-OR (1,2

139 galactosyltransferase much like the acceptor trisaccharide, GlcNAcbeta1-2Manbeta1-6Man, which is pres

140 pha1,6-Manbeta-OR (1,2-1,6-arm); the 1,3-arm trisaccharides, GlcNAcbeta1,2-Manalpha1,3-Manbeta-OR (1,

141 ta-2S-iduronate to expose the fully sulfated trisaccharide (GlcNS(6S)-IdoUA(2S)-GlcNS(6S)) does initi

142 streamline the synthesis of the globo series trisaccharides (globotriaose and isoglobotriaose) and al

143 sfully applied to the synthesis of digitoxin trisaccharide glycal for the direct synthesis of digitox

144 ltransferase, we prepared a library of Le(x) trisaccharide glycans bearing a wide variety of function

145 olyclonal sera from rabbits immunized with a trisaccharide glycoconjugate.

146 It was further observed that the trisaccharide GPI analogues 5 and 6 were better SrtA sub

147 studies of a set of eight synthetic HEP-like trisaccharides harboring different sulfation patterns de

148 zed side chain incorporated in the west wing trisaccharide have been synthesized.

149 OS with one to five repeats of the terminal trisaccharide, having at the nonreducing end a GlcNAc or

150 orcing the proximal beta-linked sugar of the trisaccharide head group to adopt the typical binding or

151 Incorporation of GalNAc Gb3 trisaccharide in a heterobifunctional ligand with an att

152 glycosyltransferases assemble a similar core trisaccharide in both organisms, and a bifunctional alph

153 highly specific TFF2 binding to the 6-linked trisaccharide in GlcNAcalpha1-4Galbeta1-4GlcNAcbeta1-6(F

154 x), and the Le(a) trisaccharide to the Le(x) trisaccharide in Le(a)Le(x), was found to be very flexib

155 The decrease in yield after the trisaccharide in the (1-->2)-mannan synthesis is attribu

156 t monosaccharides, six disaccharides and two trisaccharides in (0.25, 0.50, 1.00 and 1.50)molkg(-1) a

157 glycosidic bond that connects the two Le(x) trisaccharides in dimLe(x), and the Le(a) trisaccharide

158 nked glycan trimannoside and Le(X) and Le(A) trisaccharides in very good yield (76%, 62%, and 59% yie

159 Con A with a synthetic analog of the natural trisaccharide, in which a hydroxyethyl side chain replac

160 he synthesis of two Streptococcus pneumoniae trisaccharides, in which the applicability of the two si

161 Here, we use this technique to show that trisaccharides increase the apparent thermodynamic bindi

162 >4)-, and alpha/beta-(1-->6)-linked glucosyl trisaccharides into the SP-D carbohydrate recognition do

163 This linear B trisaccharide is a component of porcine tissues and orga

164 The alpha-GalNAc residue unique to the A trisaccharide is buried deeply in the NV binding pocket,

165 The modified trisaccharide is more buried and fits more snugly than t

166 of any of the Stx forms, indicating that the trisaccharide is necessary for binding.

167 ide of the Salmonella anatum group E(1) core trisaccharide is presented in which all three glycosidic

168 Antibody recognition of the di- and trisaccharide is primarily dependent on the mannose unit

169 ther fully protected thioglycoside, a di- or trisaccharide is selectively formed without self-condens

170 In the second step, the trisaccharide is specifically hydrolyzed by trehalase, t

171 A new cyclic trisaccharide is synthesized by cycloglycosylation of a

172 residues, in alpha-linkages to the Skp1 core trisaccharide, is unexpectedly critical for oxygen-depen

173 alactosyldiacylglycerol) and the beta-linked trisaccharide (isoglobotriaosylceramide), is unclear.

174 to form beta-(1 --> 2),beta-(1 --> 3)-linked trisaccharides, isolated in excellent 95% yield.

175 e state of substance P as well as individual trisaccharide isomers from a mixture of melezitose and r

176 s paper, we focus on the conformation of the trisaccharide Le(x) (Gal[Fucalpha(1-3)]beta(1-4)GlcNAc).

177 endent and inhibitable by fucose and Lewis-x trisaccharides (Le(x)).

178 13C-1H couplings for a bound trisaccharide ligand, methyl 3,6-di-O-(alpha-D-mannopyra

179 abeled Manalpha(1-2)Manalpha(1-2)ManalphaOMe trisaccharide ligand, when bound to cyanovirin-N (CV-N),

180 ide bound to the enzyme, and the 1,2-1,6-arm trisaccharide makes the maximum number of interactions w

181 at this receptor has a high affinity for the trisaccharide maltotriose (K(d)<1 microM) but little aff

182 ecies that selectively binds and engulfs the trisaccharide Manalpha1-3(Manalpha1-6)Man over mannose o

183 le to discriminate between the three related trisaccharides methyl Manalpha(1-2)Manalpha(1-2)Man, met

184 binding to biantennary glycans expressing Pk trisaccharide mimics immobilized on streptavidin, result

185 saccharide, N-acetylneuraminic acid, and the trisaccharide mixture, neuraminyl lactoses, disrupted hu

186 ould readily be prepared by employing a core trisaccharide modified by the orthogonal protecting grou

187 ynthesized by cycloglycosylation of a linear trisaccharide, modified with hydroxymethyl moiety at C4

188 NAc-3-SO4-bearing trisaccharides (6.7 mol of trisaccharide/mol of bovine serum albumin) have K(i) val

189 xtending across both subdomains in which the trisaccharide molecule is oriented perpendicular to the

190 the terminal branch of GD1a as well as this trisaccharide motif alone, corresponding to the sialyl-T

191 Phosphorylated O-mannosyl trisaccharide [N-acetylgalactosamine-beta3-N-acetylgluco

192 nantioselective and straightforward route to trisaccharide natural products digoxose and digitoxin ha

193 nevoltage) fragment ion corresponding to the trisaccharide Neu5Acalpha2-->3(or 6)Galbeta1-->4GlcNAc f

194 calpha2-6, as well as the affinities for the trisaccharide Neu5Acalpha2-8Neu5Acalpha2-8Neu5Ac versus

195 We thus synthesized the terminal trisaccharide, NeuAc(alpha2-8)NeuAc(alpha2-3)Gal common

196 tegy consisted first in the synthesis of the trisaccharide O-beta-d-Fruf-(2<-->6)-O-alpha-d-Glcp-(1<-

197 The resulting trisaccharide obtained in 23% molar yield based on treha

198 e with laminaritetraose and the other with a trisaccharide of 1,3-1,4-beta-d-glucan, have been determ

199 This study shows: (i) that the non-terminal trisaccharide of heparin is sufficient to initiate the s

200 Stx1 preferred the Pk trisaccharide of its native receptor, globotriaosylceram

201 Mutations affecting the terminal trisaccharide of lipopolysaccharide resulted in reduced

202 , and is inhibited by the synthetic terminal trisaccharide of PGL-1.

203 inia enterocolitica O:50 strain 3229 and the trisaccharide of Pseudomonas chlororaphis subsp. aureofa

204 of H type 1 and Globo H and of the terminal trisaccharides of A type 1 and Globo A.

205 ng the non-reducing terminal mono-, di-, and trisaccharides of Skp1 revealed, surprisingly, that the

206 RBC36 binds the H-trisaccharide on the concave surface of the LRR modules

207 he alpha chain required a terminal Gal and a trisaccharide or longer oligosaccharide to serve as an a

208 between the amount of sugar (monosaccharide, trisaccharide, or heptasaccharide) in the reductive amin

209 finity ligand (the terminally phosphorylated trisaccharide P-Man(alpha1,2)Man(alpha1,2)Man-O-(CH(2))(

210 n streptavidin, resulting in display of four trisaccharides per streptavidin face.

211 er a complex trisaccharide (B. pertussis), a trisaccharide plus an O-antigen-like repeat (B. bronchis

212 ke repeat (B. bronchiseptica), or an altered trisaccharide plus an O-antigen-like repeat (B. parapert

213 Stx1 primarily recognizes the Pk-trisaccharide portion and has three Pk binding sites per

214 The cyclic trisaccharide possesses a rarely observed perfect trigon

215 The trisaccharides prepared from (13)C6(glc) sucrose and lac

216 entasaccharide and several GlcNAc-containing trisaccharides present in N-glycans.

217 o confirmed the absence of a possible pseudo-trisaccharide product.

218 We conclude that the terminal trisaccharide protects Bordetella species from the bacte

219 ccharide composition with preference for the trisaccharides raffinose and panose.

220 gentiobiose nigerose, and kojibiose), and 7 trisaccharides (raffinose, isomaltotriose, erlose, melez

221 nteracts preferentially with the 1,2-1,6-arm trisaccharide rather than with the 1,2-1,3-arm or 1,4-1,

222 branched core structure with a nonrepeating trisaccharide, rather than a long-chain repeating O-Ag.

223 ent forms of these 4-sulfated and 3-sulfated trisaccharides reflects a difference in the impact of co

224 heteropolysaccharide chains comprised of the trisaccharide repeat unit Fuc4NAc-ManNAcA-GlcNAc, where

225 al common antigen (ECA) are comprised of the trisaccharide repeat unit Fuc4NAc-ManNAcA-GlcNAc, where

226 P-undecaprenol (lipid III), the donor of the trisaccharide repeat unit in the biosynthesis of enterob

227 tion of undecaprenylpyrophosphate-linked ECA trisaccharide repeat units and the polymerization of tri

228 Individual trisaccharide repeat units are assembled as undecaprenyl

229 In contrast, WbdA(O8) polymerizes trisaccharide repeat units containing single alpha-(1-->

230 phorylundecaprenol (lipid III), the donor of trisaccharide repeat units for ECA polysaccharide chain

231 nalyses and show for the first time that the trisaccharide repeat units of ECA(CYC) and ECA(PG) are a

232 ecules lacked an aglycone and contained four trisaccharide repeat units that were nonstoichiometrical

233 revealed that they uniformly contained four trisaccharide repeat units, and they were substituted wi

234 aride repeat units and the polymerization of trisaccharide repeat units, respectively.

235 a fucosyl residue in one of the five O-chain trisaccharide repeat units.

236 Ac transferase involved in the synthesis ECA trisaccharide repeat units.

237 The O-PS of strain CU1000 consisted of a trisaccharide repeating unit composed of L-rhamnose and

238 e preparation of structural analogues of the trisaccharide repeating unit from Streptococcus pneumoni

239 The polysaccharide is comprised of a trisaccharide repeating unit having the structure -->4)-

240 ruginosa O11 lipopolysaccharide, which has a trisaccharide repeating unit similar to that of the S. a

241 ECA, a heteropolysaccharide built from the trisaccharide repeating unit, -->3)-alpha-D-Fucp4NAc-(1-

242 rom S. haemolyticus strain JCSC1435 showed a trisaccharide repeating unit: -3-alpha-L-FucNAc-3-(2-NAc

243 Since CP5 and CP8 have similar trisaccharide repeating units, it is important to identi

244 nd ITC the binding of CVN to three synthetic trisaccharides representing the full-length D1, D2 and D

245 galactosyltransferase required to extend the trisaccharide, require elevated O(2) as for P4H1-null ce

246 A hetero-trisaccharide resin glycoside of jalapinolic acid known

247 synthesis, makes use of the coupling of two trisaccharides, resulting in a shorter sequence and an o

248 but bind monosaccharides, disaccharides, or trisaccharides reveals the presence of four subsites tha

249 A-Rha B-Rha C-GlcNAc D-Rha A' and a modified trisaccharide Rha B-Rha C-GlcNAc D in which Rha C* is mi

250 The clicked mannose, lactose, and alpha-Gal trisaccharide SAMs were used in the analysis of specific

251 the nonreducing and reducing ends of the IAI trisaccharide sequence.

252 Modification of the acyl chain domain in the trisaccharide series revealed that a terminal carboxylic

253 Multiple pentasaccharide and trisaccharide side chains are O linked to BclA.

254 of donor and acceptor performance up to the trisaccharide stage in solution and on the solid support

255 f His(6)-HFR1 to Manalpha1-6(Manalpha1-3)Man trisaccharide structures.

256 analysed in terms of a series of overlapping trisaccharide substructures.

257 s to the naturally occurring mono-, di-, and trisaccharide substructures.

258 rasaccharide structure, all disaccharide and trisaccharide subunits of the GPI backbone have been stu

259 tB resulted in BclA being replaced with only trisaccharides, suggesting that the enzyme encoded by th

260 he observation of a tighter complex with the trisaccharide than the pentasaccharide.

261 is a pentasaccharide containing the Lewis(x) trisaccharide that is found on schistosome eggs and in b

262 1-->4)-beta-ManNAc-(1-->4)-beta-GlcNAc-(1--> trisaccharide that is substituted with beta-Gal at O3 of

263 des displaying a C-linked analogue of the Pk trisaccharide, the in vivo ligand for the pentavalent Sh

264 patterns identical to those of the reference trisaccharides, thus providing a method for confirming t

265 ptica core oligosaccharide with one terminal trisaccharide to aminooxylated BSA via their terminal ke

266 x) trisaccharides in dimLe(x), and the Le(a) trisaccharide to the Le(x) trisaccharide in Le(a)Le(x),

267 rom 12 sialylated carbohydrates ranging from trisaccharides to biantennary N-linked glycans.

268 d 6-O-sulfated oligosaccharides ranging from trisaccharides to nonasaccharides.

269 g five isomeric disaccharides, four isomeric trisaccharides, two isomeric pentasaccharides, and two i

270 level was determined by ELISA using alphaGal trisaccharide type 2-BSA glycoconjugate as antigen targe

271 alphaGal-BSA glycoconjugates: (disaccharide, trisaccharides type 2 and 6, and pentasaccharide).

272 We used two synthetic alphaGal trisaccharides--type 6 (alphaGal6) and type 2(alphaGal2)

273 were more stable to heat treatment than were trisaccharides under all of the conditions tested.

274 ), was designed to mimic the nonreducing end trisaccharide unit DEF of the sequence specific heparin

275 evidence for the involvement of the specific trisaccharide unit of the phenolic glycolipid-1 (PGL-1)

276 osa PAO1 (serotype O5) comprises a repeating trisaccharide unit that is critical for virulence and pr

277 skali is composed of the following repeating trisaccharide unit: --> 3)GalNAcbeta4,6S(1 --> 4) [Fucal

278 e that MLG in brown algae solely consists of trisaccharide units of contiguous (1 --> 4)-beta-linked

279 inear tetrasaccharide domain revealed that a trisaccharide variant is equipotent to QS-21, while the

280 Thus, after the trisaccharide was prepared and linked to Asn, the carboh

281 Finally, in contrast to the small trisaccharides, we demonstrated that a longer HEP-like h

282 utants of either strain lacking the terminal trisaccharide were aggregated and permeabilized by SP-D.

283 cking even one of the sugars in the terminal trisaccharide were bound and aggregated by SP-A.

284 A; however, LPS mutants lacking the terminal trisaccharide were susceptible to SP-A.

285 The NMR spectra of the three trisaccharides were fully assigned, and their structures

286 demonstrated by the synthesis of the Galili trisaccharide, which has been identified as an epitope t

287 se SRCL are highly specific for the Lewis(x) trisaccharide, which is commonly found on the surfaces o

288 . bronchiseptica mutant lacking the terminal trisaccharide, while wild-type B. bronchiseptica and mut

289 Elongation of the trisaccharide with PglH results in a hexasaccharide reve

290 lly relevant variant, Stx2, preferred the Pk trisaccharide with the terminal galactose replaced with

291 also shares carbohydrate recognition of this trisaccharide with toxin A elaborated by Clostridium dif

292 ongated with high efficiency, both contain a trisaccharide with two glucuronic acid residues that ena

293 donors to prepare various disaccharides and trisaccharides with good to excellent beta-selectivity.

294 with remarkable selectivity, and binds these trisaccharides with K(A) values ranging from 8.1x10(3)M(

295 is less selective in that it binds all three trisaccharides with similar K(A) values ranging from 1.7

296 th disaccharides were identified as branched trisaccharides, with a glucosyl residue alpha-(1 --> 2)-

297 at all sites is efficiently elongated to the trisaccharide Xyl-Xyl-Glc.

298 O-Glucose can be elongated by xylose to the trisaccharide, Xylalpha1-3Xylalpha1-3Glcbeta1-O-Ser, who

299 elongating the glycan to generate the final trisaccharide xylose-xylose-glucose, however, remained u

300 allenging Gal-alpha-(1-4)-Gal linkage in Gb3 trisaccharide yielded the desired alpha linkage almost e