ライフサイエンスコーパス: tritiate

1 ge conversion of tritiated corticosterone to tritiated 11-dehydrocortico-sterone when corticosterone

2 detail a synthetic method that easily gives tritiated 2-AG from [5,6,8,9,11,12,14,15-(3)H(N)]arachid

3 radiolabeled endocannabinoid as needed gave tritiated 2-arachidonoylglycerol [(3)H]2-AG with a speci

4 ght into this unique enzymatic reaction, the tritiated 2-methylene-ACC was prepared and incubated wit

5 gain further insight into this inactivation, tritiated 2-methylene-ACC was prepared and used to trap

6 ssay, mitochondrial dehydrogenase assay, and tritiated [3H] thymidine incorporation, respectively.

7 properties of purified alpha v beta 3, using tritiated [3H]SK&F-107260 as the radiolabeled ligand.

8 ults in transfer of (3)H to AdoMet, while no tritiated 5'-deoxyadenosine is observed.

9 incubated sections of rat visual cortex with tritiated (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]-cyc

10 incubated sections of cat visual cortex with tritiated (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]-cyc

11 20 microCi of tritiated 8-iso-PGF2alpha was infused over 1 h into a ma

12 In the first experiment, tritiated ABA ((3)H-ABA) and gibberellic acid ((3)H-GA3)

13 Transport of label after application of tritiated abscisic acid showed no polarity and was not a

14 lga Chlamydomonas reinhardtii was studied by tritiated acetate incorporation.

15 netics can explain the functional contrasts, tritiated Ad5 E1A and HPV16 E7 peptides were injected in

16 chromatography and RPE cultures labeled with tritiated adenine or myo-inositol, respectively.

17 Tritiated adenosylcobalamin, labeled at the exchangeable

18 When 5'-tritiated AdoMet is used in the reaction with unlabeled

19 The generation of all-trans retinal from tritiated all-trans retinol was analyzed by HPLC.

20 Tritiated amino acid injections into CA1, prosubicular,

21 Tritiated amino acid injections were placed into the hip

22 clei and by mapping anterograde transport of tritiated amino acid precursors injected into the dentat

23 n e maleate (MK-801), tritiated kainate, and tritiated amino-3-hydroxy-5-methyl-isoxazole-4-propionic

24 n e-maleate (MK-801), tritiated kainate, and tritiated amino-3-hydroxy-5-methyl-isoxazole-4-propionic

25 lo[1,5-a]pyridine ((11)C-Lu AE92686) and its tritiated analog (3)H-Lu AE92686.

26 Furthermore, using a tritiated analog of the NOS inhibitor N(G)-nitro-L-argin

27 cGMP-dependent protein kinase (PKG) using a tritiated analogue to purify a approximately 120-kDa pro

28 promising radioligand, and the corresponding tritiated and (11)C-labeled compounds were synthesized.

29 om TLR4 and CD14 knockout C57BL/6 mice using tritiated and fluorescein-labeled LPS.

30 m of binding of the synthesized compounds, a tritiated antagonist, (R)-N(alpha)-diphenylacetyl-N(omeg

31 Tritiated arachidonic acid and phosphatidylinositol 3,5-

32 proton abstraction using a peptide with Glu tritiated at the gamma-carbon position revealed that poo

33 initial DHAP concentration using DHAP highly tritiated at the pro-R position.

34 Equilibrium binding studies utilizing a tritiated ATP-competitive inhibitor were also consistent

35 bstitution for F1764 (mutant F1764A) reduces tritiated BTX-A-20-alpha-benzoate binding affinity, caus

36 tation of caveolin-1 from cells labeled with tritiated cholesterol or the photoactivable cholesterol

37 greater sensitivity and resolution than the tritiated compound.

38 ovalent attachment of the biotin moiety to a tritiated compound.

39 The direct comparison of uptake of tritiated compounds demonstrated more efficient system x

40 Binding of tritiated compounds to brain tissue sections of AD patie

41 mogenized rat eyes (percentage conversion of tritiated corticosterone to 11-dehydrocorticosterone; me

42 eye assessed as the percentage conversion of tritiated corticosterone to tritiated 11-dehydrocortico-

43 d by a standard receptor binding assay using tritiated CP-55,940 as the radioligand and compared to a

44 Bidirectional transport of tritiated CSA, verapamil, and dexamethasone (0.5 or 5.0

45 ssessed by quantitative autoradiography with tritiated cyanoimipramine ([(3)H]CN-IMI), was decreased

46 the SSRI sertraline were investigated using tritiated cyanoimipramine to measure SERT binding sites.

47 The tracers employed were tritiated cyclic nucleotides and a series of oligomaltos

48 LSK274, tritiated His262; 176NGGTLYTCALR186, tritiated Cys183; and 353TVEWVGSLVDR363, tritiated Trp35

49 Binding of tritiated cytisine and nicotine to cell homogenates reve

50 F-FDG signal, we have measured the uptake of tritiated deoxyglucose (DG) in neutrophils isolated from

51 eled ligands, and we therefore synthesized a tritiated derivative of (2S,3S)-3-{3-[4-ethylbenzoylamin

52 The P-gp substrate, tritiated digoxin ([(3)H] digoxin), was co-administered

53 et, acylpeptide hydrolase, was isolated as a tritiated-diisopropylfluorophosphate-reactive protein fr

54 n was also deduced by specific labeling with tritiated-diisopropylfluorophosphate.

55 kappa sensitization, the present study used tritiated dopamine release assays to examine the inducti

56 No changes were seen in release of tritiated dopamine, in response to applied KCl or amphet

57 heir effect on human MRP1-mediated uptake of tritiated estradiol glucuronide into inside-out membrane

58 valuate the intracellular phosphorylation of tritiated F-18 FDG in human lung cancer and breast cance

59 The biodistribution of tritiated-FK506 administered i.v. showed that the drug r

60 discovery of both PF-04725379 (11), which in tritiated form became a novel ligand for characterizing

61 cally relevant as possible, we synthesized a tritiated form of the specific P. aeruginosa glycolipid

62 A tritiated form of volicitin was synthesized and shown to

63 Brain sections were labeled with the tritiated forms of mu-, delta- and kappa-opioid ligands;

64 Tritiated forms of polyglutamyl folates are not commerci

65 During intravenous glucose tolerance tests, tritiated glucose (1.2 microCi/kg) was injected with col

66 Tritiated glucose infusion was used to measure rates of

67 A 3-tritiated glucose was used to determine glucose kinetics

68 in euglycemic cycling exercise at 50% VO2max Tritiated glucose was used to measure glucose kinetics.

69 Glucose kinetics were determined by three-tritiated glucose, and muscle sympathetic nerve activity

70 Glucose kinetics was determined by 3-tritiated glucose.

71 rats, glucose kinetics was determined using tritiated glucose.

72 tic peptide (135EIIQNGHEEEPLENTWPAPYPHSK159, tritiated His142).

73 ic peptides: 251GQFYYISDDTPHQSYDNLNYTLSK274, tritiated His262; 176NGGTLYTCALR186, tritiated Cys183; a

74 ed by NaB(3)H(4) reduction and the resulting tritiated hydroxy fatty acid then is tosylated, separate

75 viously described using azido-Q that was not tritiated (i.e., not radiolabeled).

76 olar auxin transport was measured by tracing tritiated IAA in excised shoots.

77 However, ATP can compete with the tritiated inhibitor for binding to only the active form

78 Upon combining the tritiated inhibitor with [2-14C]-thiamin diphosphate, no

79 le 1 was also effective in stimulating basal tritiated inositol monophosphate production in the neona

80 Yeast cells are incubated with tritiated inositol, which is taken up and metabolized in

81 ole level by reaction of dithiothreitol with tritiated iodoacetic acid (I-C[3H(2)].CO(2)H).

82 pled to isothermal titration calorimetry and tritiated IP(6) binding assays confirmed two-site bindin

83 An improved microscale synthesis of 2-tritiated isopropanol ([2-3H]iPrOH) and R-tritiated redu

84 ,d]-cyclohepten-5,10imin e maleate (MK-801), tritiated kainate, and tritiated amino-3-hydroxy-5-methy

85 ,d]-cyclohepten-5,10imin e-maleate (MK-801), tritiated kainate, and tritiated amino-3-hydroxy-5-methy

86 DL forms of the dipeptide Leu-Leu inhibited tritiated L-carnosine uptake by approximately 60%, 40%,

87 uated by computer modeling and inhibition of tritiated L-carnosine uptake.

88 Uptake of tritiated L-carnosine was monitored using conjunctival e

89 uman placental villi incubated in vitro with tritiated leucine ([3H]leu).

90 eradish peroxidase, and autoradiography with tritiated leucine and/or proline.

91 Three tracers were utilized: tritiated leucine, biotinylated dextran amine, and wheat

92 esicles from mice lacking SV2A do not bind a tritiated LEV derivative, indicating that SV2A is necess

93 Tritiated ligands used to measure binding site density w

94 (4 h+) showed a substantial concentration of tritiated macromolecules in the Golgi complex and in the

95 e autoradiographic evidence for secretion of tritiated macromolecules.

96 ubunit, we labeled rod outer segments with a tritiated methyl donor.

97 3T3-L1 adipocytes increased incorporation of tritiated mevalonic acid in p21(ras) in a dose-dependent

98 Tritiated misonidazole (3H-MISO) is a marker which prefe

99 ptor of interest are labeled by feeding with tritiated myo-inositol.

100 Both lactam analogues competed with tritiated [Nle12]-alpha-factor for binding to the alpha-

101 ssues were then removed and analyzed for the tritiated NNK and its metabolites.

102 One hundred ng of tritiated NNK were instilled in the distal trachea of th

103 ce quenching and saturation equilibrium with tritiated ouabain, Ab 1-10 exhibited 200 nM affinity for

104 THA EF with fractional water production from tritiated palmitate further confirms a correlation of th

105 idation rates were determined by infusion of tritiated palmitate into the left anterior descending ar

106 n rates, determined by water production from tritiated palmitate.

107 Maximal number of platelet tritiated paroxetine binding sites (Bmax) and dissociati

108 The Bmax, but not Kd, values of platelet tritiated paroxetine binding was inversely correlated wi

109 ing isolated bovine neutrophils labeled with tritiated phospholipid substrates of the two enzymes.

110 Tritiated photoaffinity analogs of the natural lepidopte

111 in a 113 +/- 11% increase in the amounts of tritiated platelet-activating factor ((3)H-PAF) released

112 c acid at 0 degree C, significant amounts of tritiated polyuridylic acid are converted to acid-solubl

113 lability and permit quantitative recovery of tritiated polyuridylic acid by trichloroacetic acid prec

114 ic acid precipitation is used to recover the tritiated polyuridylic acid present in a hybrid with pol

115 ctivity can occur because of the lability of tritiated polyuridylic acid.

116 toanesthesia." Coupling this behavior with a tritiated probe, we performed unbiased, time-resolved ge

117 P81 after intravitreous injections of either tritiated proline or wheat germ agglutinin-horseradish p

118 Tritiated proline was injected into the right eye 1 d af

119 Second, intravitreal injections of tritiated proline were used to identify hypothalamic ret

120 ed with tritiated sodium borohydride and the tritiated proteins were separated on SDS-PAGE.

121 We have found that a tritiated pyridinylimidazole, SB202190, has an equal aff

122 n proximity assay technology: binding of the tritiated radioligand to the commercially available stre

123 2-tritiated isopropanol ([2-3H]iPrOH) and R-tritiated reduced beta-nicotinamide adenine dinucleotide

124 ed specific and saturable nuclear binding of tritiated RU1881 and that alpha-DHT stimulated the activ

125 ations were functionally characterized using tritiated ryanodine binding and single-channel recording

126 dded to methylate the resulting peptide with tritiated S-(5'-adenosyl)-l-methionine.

127 nd to frog Rh* and P-Rh* and to compete with tritiated SalArr1 for amphibian P-Rh* was compared.

128 Complexes of tritiated SH2 fusion protein and biotinyl-phosphopeptide

129 atelets modified by WR-K and then reduced by tritiated sodium borohydride (NaB[3H]4) showed the prese

130 Protein carbonyls were derivatized with tritiated sodium borohydride and the tritiated proteins

131 e chromatography, we were able to detect one tritiated species which co-migrated with an omega-NG-mon

132 e chromatography, we were able to detect two tritiated species.

133 xogenously added radiolabeled ATP instead of tritiated sphingosine.

134 xpressing either D2 or D3 receptors by using tritiated spiperone as radioligand for competition studi

135 lls expressing either D2 or D3 receptor with tritiated spiperone to evaluate inhibition constants (K(

136 ls expressing either D2 or D3 receptors with tritiated spiperone to evaluate inhibition constants (K(

137 ls expressing either D2 or D3 receptors with tritiated spiperone to evaluate inhibition constants (Ki

138 constant and enthalpy of activation for the tritiated substrate from competitive KIE experiments.

139 of tritiated water after the addition of the tritiated substrate was detected and used to measure DES

140 percentage of SNB motoneurons to accumulate tritiated testosterone or its metabolites.

141 xogenous KL to the MLR led to an increase in tritiated thymidine (3[H]-TdR) incorporation in the abse

142 njected intraperitoneally (twice daily) with tritiated thymidine (3H-TdR), beginning at 17 days of ge

143 ed to the radioactive DNA replication marker tritiated thymidine ([(3)H]dT, or TdR) at early embryoni

144 CHO cells were labeled with tritiated thymidine ([3H]dTTP) for 12 hours and subseque

145 ion was determined by labeling cultures with tritiated thymidine ([3H]TdR) and scoring its incorporat

146 1.6 [95% CI 0.5-5.1]) or change in uptake of tritiated thymidine (counts per minute) (OR 0.7 [95% CI

147 This was confirmed by injecting tritiated thymidine 24 hr after the BrdU and seeing no d

148 Tritiated thymidine and autoradiographic techniques and

149 Tritiated thymidine and autoradiographic techniques were

150 cells induced to enter S were measured with tritiated thymidine and radioautography.

151 with peptides of streptococcal M5 protein in tritiated thymidine assays.

152 Tritiated thymidine autoradiography and bromodeoxyuridin

153 By using tritiated thymidine autoradiography, we observed that th

154 Tritiated thymidine based lymphocyte proliferation assay

155 rough successive divisions; DNA labeled with tritiated thymidine in infancy is still present in the s

156 iameter or the number of cells incorporating tritiated thymidine in the lesion.

157 Tritiated thymidine incorporation analyses revealed sust

158 .3- and 1.6-fold increases, respectively, in tritiated thymidine incorporation and bromodeoxyuridine

159 and peripheral blood were measured by using tritiated thymidine incorporation and carboxyfluorescein

160 ed the HEP G2 doubling time in culture using tritiated thymidine incorporation and direct cell counts

161 ctionality of fetal cells was also restored; tritiated thymidine incorporation and insulin content an

162 Cell division rates were determined by tritiated thymidine incorporation and Ki67 immunoreactiv

163 and on cell proliferation, as determined by tritiated thymidine incorporation and proliferating cell

164 Tritiated thymidine incorporation assay revealed that Cu

165 With tritiated thymidine incorporation assays, we found that

166 s on CTLL-2 proliferation were determined by tritiated thymidine incorporation immediately or 24 h af

167 of RR was monitored, indirectly by measuring tritiated thymidine incorporation into DNA and directly

168 s and 1.5-fold in Ba/ F3 cells and decreased tritiated thymidine incorporation into DNA corresponding

169 Tritiated thymidine incorporation studies revealed cardi

170 or -15, cell proliferation was determined by tritiated thymidine incorporation, and IL-2 and -15 rece

171 The method involves an initial injection of tritiated thymidine into chick embryos, followed a speci

172 Incorporation of tritiated thymidine into whole brain DNA demonstrated th

173 neurogenesis was initially studied with the tritiated thymidine technique, later replaced by the inj

174 Analysis of tritiated thymidine uptake by the tibia and fibula demon

175 Proliferation was studied by using tritiated thymidine uptake with or without MSCs.

176 d immunosorbent assay, cell proliferation by tritiated thymidine uptake, and cell surface molecule ex

177 Tritiated thymidine was given 1 h before death.

178 ession of p21WAF-1/CIP1 and incorporation of tritiated thymidine were found to be mutually exclusive.

179 ll sorter analysis, continuous labeling with tritiated thymidine, and time-lapse videomicroscopy docu

180 Cultures were pulsed with tritiated thymidine, harvested, and radio label incorpor

181 Uptake of tritiated thymidine, L-leucine, L-methionine and FDG int

182 ability of pretreated leaves to incorporate tritiated thymidine, uridine, and leucine into macromole

183 TGF-beta1, as determined by incorporation of tritiated thymidine, whereas those from 5 patients were

184 e cell cycle by intraperitoneal injection of tritiated thymidine.

185 s assessed by measuring the incorporation of tritiated thymidine.

186 an unperturbed culture with a short pulse of tritiated thymidine.

187 Cell turnover, assessed by tritiated-thymidine (thymidine) autoradiography, increas

188 Tritiated-thymidine autoradiographic techniques and 5-br

189 The following five classes of tritiated-thymidine labeled cells were identified in the

190 The cell proliferation marker tritiated-thymidine was infused, with or without TGFalph

191 Two new tritiated tracers for angiotensin and neurotensin recept

192 86, tritiated Cys183; and 353TVEWVGSLVDR363, tritiated Trp356.

193 7-Tritiated valiolamine (8), valienamine (2), and validami

194 n S1, in which the side chain of Ser-180 was tritiated, was photocleaved tritium was released from th

195 pidermal water loss and skin permeability to tritiated water (3H2O) and the lipophilic penetrant sulf

196 Typically, (3)H is present as tritiated water (HTO) and can become adsorbed into struc

197 amounts of liquid tritium are discharged as tritiated water (HTO) by the nuclear industry into the E

198 st 1 order of magnitude higher than that for tritiated water (HTO), although a similar behavior could

199 g rat liver microsomes, and the formation of tritiated water after the addition of the tritiated subs

200 interpret recent laboratory measurements of tritiated water and Cs diffusivity in Callovo-Oxfordian

201 as confirmed by determining incorporation of tritiated water into fatty acids.

202 Aromatase activity, assayed by the tritiated water method, was stimulated in both frontal s

203 linear relationship of FTHA EF to fractional tritiated water production was found.

204 incorporated following prolonged exposure to tritiated water vapor (HTO) or tritium/hydrogen gas (HT)

205 ruled out by the results of experiments with tritiated water.

206 lic (probably hydroxylated) derivatives plus tritiated water.

207 aborious vacuum distillation of the released tritiated water.

208 de bond between two ligands, one of which is tritiated whereas the other is biotin-tagged.