ライフサイエンスコーパス: trough

1 m for the impending megaquake at the Nankai Trough.

2 sited on lung surfactant films in a Langmuir trough.

3 ed to CA1, which were strongest at the theta trough.

4 n this and adjacent seamounts in the Rockall Trough.

5 the air-water interface in a conical Teflon trough.

6 fluid is compressed uniaxially in a Langmuir trough.

7 o, and precede, the subthalamic nucleus beta-trough.

8 enge performed after first and last doses at trough.

9 auses simultaneous deep, broad UV absorption troughs.

10 similar with respect to timing of peaks and troughs.

11 harpness of the beta peaks compared with the troughs.

12 ics, including seasonality, abrupt peaks and troughs.

13 surface topography such as the formation of troughs.

14 ogic evaluation included assessment of serum trough adalimumab and antibodies against adalimumab (AAA

15 rmanent AAA was associated with undetectable trough adalimumab levels and worse uveitis outcome.

16 In all patients with permanent AAA+, trough adalimumab levels became undetectable (P < 0.001)

17 Median trough adalimumab serum levels were higher in responders

18 raphic positions (polygon centers, rims, and troughs) along the permafrost degradation gradient, we m

19 illator-the time of peak KOA and the peak-to-trough amplitude changes.

20 monthly and had up to 3 anti-Xa activities (trough and 1 and 3 hours after dose) drawn at each clini

21 -dependent relationship between seasonal UVR trough and relapse onset probability peak independent of

22 associations of latitude and lag between UVR trough and subsequent relapse peak.

23 explanation for enhanced transmission during troughs and an associated seasonal monsoon response in t

24 iles were processed to enhance the peaks and troughs, and then an exclusion or inclusion criterion ba

25 6780 patients with data available) and mean trough anti-FXa activity (0.35-0.85 IU/mL in 2865 patien

26 When trough anti-Xa activity was simulated, both once- and tw

27 wice-daily regimens exhibited an increase in trough anti-Xa activity with the progression of pregnanc

28 s glaciomarine and Holocene sediments in the troughs apparently limit seepage.

29 e cortex after motor skill learning, whereas troughs are required for stabilizing newly formed spines

30 0.032) and a decreased number of vancomycin trough assays performed (0.88 versus 1.95, P < 0.001).

31 g and decreased unnecessary serum vancomycin trough assays.

32 Tear production decreased to the trough at 1 month after treatment and then recovered gra

33 n, most notably characterized by an activity trough at dusk followed by a high level of male courtshi

34 We obtained trough blood samples and measured antibiotic concentrati

35 These values are close to the steady state trough brain concentration of methylthioninium ion (0.18

36 e they do occur, the resulting deep epidemic troughs break the chain of transmission, leading to epid

37 imary outcome was model-derived steady-state trough C1-INH functional activity.

38 hielding provided stronger apoptotic effects trough caspase-3 activation compared to N2 shielding.

39 The peak-to-trough circadian oscillation is paralleled by the sequen

40 cant (p < .05) increases in seasonal peak-to-trough CO2 amplitude (AMPP-T ) at nine stations, and in

41 torhinal cortex, and retrieval occurs at the trough, coincident with input from CA3, consistent with

42 Only 1 patient showed a trough concentration (Ctrough) below the suggested targe

43 n SC dose that would yield a rituximab serum trough concentration (Ctrough) in the same range as that

44 BV/PTV/r + DSV + darunavir (DRV) lowered DRV trough concentration (Ctrough) levels.

45 The alisertib steady-state trough concentration (n = 25) revealed the expected phar

46 reduced using an algorithm to reach a target trough concentration (TC) of 3-7 mug/mL in all patients

47 ugh concentration from first to second dose (trough concentration = 0.822 and 1.23 ng/mL for weeks 1

48 for weeks 1 and 2, respectively, with 24 mg; trough concentration = 0.993 and 1.47 ng/mL for weeks 1

49 olimus clearance (daily tacrolimus dose [mg]/trough concentration [mug/L]) and biopsy-proven acute re

50 the association between discharge tacrolimus trough concentration and the incidence of biopsy-proven

51 The mean+/-SD tacrolimus trough concentration at discharge (median postoperative

52 median (interquartile range) daily dose and trough concentration at time of nephrotoxicity were 400

53 eek after transplantation nor time to target trough concentration between patients later experiencing

54 One-third of patients had an adalimumab trough concentration exceeding 7 mg/L.

55 5 days and approximately 50% accumulation of trough concentration from first to second dose (trough c

56 +/- 0.3 g/day and the individual median MPA trough concentration in the time period of anticipated c

57 28.6%) of the 119 patients with a tacrolimus trough concentration less than 8 ng/mL and 19 (19.6%) of

58 on predisposed to BPAR, discharge tacrolimus trough concentration less than 8 ng/mL was associated wi

59 el-reactive antibody, a discharge tacrolimus trough concentration less than 8 ng/mL was significantly

60 o two groups based on a discharge tacrolimus trough concentration of 8 ng/mL.

61 t month 1 or in area under the curve0-4h and trough concentration when measured at months 3 and 6.

62 and positive association of the fluconazole trough concentration with the fluconazole dose (P <.001)

63 We evaluated mean TAC C0 (tacrolimus trough concentration) and TAC time in therapeutic range

64 morphism rs2244613 was associated with lower trough concentrations (15% decrease per allele; 95% conf

65 study, and correlated with plasma ritonavir trough concentrations (C24).

66 cted a pharmacokinetic study to evaluate EFV trough concentrations (Cmin) and human immunodeficiency

67 Efavirenz trough concentrations (Cmin) were predicted using popula

68 nt was the ratio of observed rituximab serum trough concentrations (Ctrough) between groups at cycle

69 lected in the standard monitoring parameter, trough concentrations (P=0.80).

70 higher doses of tacrolimus to achieve target trough concentrations and are more likely to experience

71 one-third of patients, it was observed that trough concentrations exceeded the therapeutic window.

72 Similarly, median (IQR) time-averaged trough concentrations in breast milk were 3.3 ng/mL (2.3

73 creased proportionally up to 120 mg/day with trough concentrations in the in-vitro active range from

74 of dosage to maintain whole blood tacrolimus trough concentrations in the usual therapeutic range can

75 Trough concentrations increased less than proportionally

76 Although non-trough concentrations might have underestimated the freq

77 cipients randomized to everolimus, targeting trough concentrations of 3-8 or 6-12 ng/mL plus reduced-

78 5 mg/m(2) per day (titrated to achieve blood trough concentrations of 5-15 ng/mL) or placebo.

79 sted subject to tolerability to attain blood trough concentrations of 5-15 ng/mL.

80 apy might not be a direct function of plasma trough concentrations of C1 inhibitor.

81 The mean steady state peak and trough concentrations of rituximab were 461 mug/mL (SD 9

82 rted medication adherence scale and IS blood trough concentrations over 6 months, in four transplant

83 pregnancy make interpretation of whole blood trough concentrations particularly challenging.

84 reached during cycle 3 with mean maximum and trough concentrations ranging from 419 mug/mL (geometric

85 Everolimus trough concentrations targeted to 3-8 ng/mL, along with

86 e were no significant differences in neither trough concentrations the first week after transplantati

87 Steady-state trough concentrations were reached by day 15 and did not

88 rican Americans (n=684), but mean tacrolimus trough concentrations were similar.

89 The median proportion of tacrolimus trough concentrations within the target range was compar

90 e polymorphism rs2244613 was associated with trough concentrations, and the ABCB1 single-nucleotide p

91 emic exposure of tacrolimus, despite similar trough concentrations, may in the long run increase the

92 tles inoculated with the peak, midpoint, and trough concentrations, respectively (P </= 0.001).

93 ic outcomes it is recommended to monitor IFX trough concentrations.

94 erse event-related dose reductions at higher trough concentrations.

95 observed only in the presence of antibiotic trough concentrations.

96 ts achieving predefined reduced cyclosporine trough concentrations.

97 re of basking white butterflies mimics the V-trough concentrator which is designed to increase solar

98 h can access thick ice shelves via submarine troughs crossing the continental shelf.

99 of ischemic events was inversely related to trough dabigatran concentrations (p = 0.045), with age a

100 the presence of anti-drug antibodies and non-trough drug concentrations could predict treatment respo

101 ng and explores the performance of different trough drug concentrations for anti-tumor necrosis facto

102 ictive value of anti-drug antibodies and non-trough drug concentrations on treatment response (DeltaD

103 in a two-fold to three fold gradient of mean trough drug exposure (16.0-48.5 ng/mL in 6780 patients w

104 (PT) are less sensitive and may be normal at trough drug levels.

105 outbreaks and the intervening inter-epidemic trough during which fadeout of transmission was most lik

106 studied on the planar surface of a Langmuir trough, even though most physiological interfaces are cu

107 We assessed the efficacy and safety of two trough exposure concentrations of everolimus, 3-7 ng/mL

108 P = .27]), and the key secondary end point, trough FEV1 (5 mug, 87 mL [95% CI, 19-154; P = .01]; 2.5

109 The primary end point analyzed was change in trough FEV1 (DeltaFEV1) from baseline to 8 to 12 weeks o

110 imary endpoints were change from baseline in trough FEV1 and in St. George's Respiratory Questionnair

111 Significant improvements in trough FEV1 at week 24 (a secondary end point) were obse

112 Evening trough FEV1 at Week 24 was not statistically significant

113 ter improvements in the primary end point of trough FEV1 compared to salmeterol after 4 weeks of dosi

114 Both doses of UMEC plus VI also improved trough FEV1 compared with VI monotherapy (UMEC 125 mug p

115 At week 12, the estimated least squares mean trough FEV1 difference between the groups was -0.011 L (

116 FP 100 mcg twice daily improved evening trough FEV1 in patients with mild-to-moderate persistent

117 In both studies, we noted improvements in trough FEV1 on day 169 for both doses of UMEC plus VI co

118 d within the first 3 h after evening dosing; trough FEV1 response; and responder rate assessed accord

119 Peak and trough FEV1 responses were significantly greater with ti

120 lmeterol group (all p<0.0001); difference in trough FEV1 was 146 mL (95% CI 105-188), 180 mL (138-221

121 in COPD, including lung function (100 ml for trough FEV1), dyspnea (improvement of >/= 1 unit in the

122 cs characterized by significantly lower peak-trough fluctuations.

123 the mammalian jaw hinge and the postdentary trough for mandibular attachment of the middle ear-a tra

124 endpoint was change from baseline in evening trough forced expiratory volume in 1 s (FEV1 ) at Week 2

125 Improvement in trough forced expiratory volume in 1 s (FEV1) and the in

126 dacaterol was non-inferior to tiotropium for trough forced expiratory volume in 1 s (FEV1) at week 12

127 rimary efficacy endpoint of both studies was trough forced expiratory volume in 1 s (FEV1) on day 169

128 adjusted mean reduction from baseline in the trough forced expiratory volume in 1 second was 38 ml gr

129 administration, a dose-dependent increase in trough functional C1-INH activity was observed.

130 ier dry season GPP loss and enhanced peak-to-trough GPP in tropical forests within the Amazon Basin a

131 quency and magnitude of population peaks and troughs greatly impact the accuracy of our CC response m

132 Donors in the G6PDd group had lower trough hemoglobin in postoperative period (P = 0.006), g

133 We find a sharp trough in gestation length among babies conceived in May

134 The May trough in gestation length coincides with a higher influ

135 bly from season to season with a significant trough in winter.

136 oidal pattern with peaks in early spring and troughs in autumn in both hemispheres.

137 st performance occurring when the respective troughs in both neural oscillations coincided.

138 Peak and trough IOP were monitored with a pneumatonometer and ton

139 As the water in the trough is drained, the monolayer is deposited on a suppo

140 with a peak at the time of the reach-end and troughs just before and after it.

141 Ninety-six percent had at least 1 trough level >/=100 U/L.

142 who received enoxaparin adjusted by anti-Xa trough level (adjustment group) were compared with those

143 m level of uric acid, and blood cyclosporine trough level (C0) and used higher doses of cyclosporine

144 m level of uric acid, and blood cyclosporine trough level (C0) and used higher doses of cyclosporine

145 late and vitamin B12, and blood cyclosporine trough level (C0) are independently associated with tHcy

146 3), and BUN (P=0.05), and blood cyclosporine trough level (C0, P=0.005) were independently associated

147 Mean TAC trough level (Cmin), used to adjust daily dose, was not

148 Patients received EVL (target trough level (Ctrough, 3-8 ng/mL), prednisone, and tacro

149 Long-term target TAC trough level and MMF dosing were 5 to 7 ng/mL and 1,000

150 Adalimumab trough level and PASI score at the time of serum samplin

151 ine whether targeting a prophylactic anti-Xa trough level by adjusting the enoxaparin dose would redu

152 Similar to younger recipients TAC trough level has also a high correlation (R = 0.76) with

153 sodium is dosed by anti-factor Xa (anti-Xa) trough level is not well described.

154 Patients with a trough level of 0.1 IU/mL or lower received enoxaparin s

155 ofetil (MMF; target plasma mycophenolic acid trough level of 1.5-2.5 microg/ml) or CsA (target trough

156 h level of 1.5-2.5 microg/ml) or CsA (target trough level of 80-100 ng/ml) in 60 pediatric patients w

157 No correlation between ribavirin trough level on day 7 or at month 2 with a virological r

158 Sirolimus remained > 5 mug/L, the trough level used in oral immunosuppressive therapy, for

159 Imatinib plasma trough level was performed at day 22 and if <1000 ng/mL,

160 roviding 3 adjusted doses of enoxaparin, the trough level was redrawn and the dosage was adjusted as

161 ightly, adjusted according to serum anti-HBs trough level) if they were HBsAg- and HBV-DNA negative a

162 paradigm promoter P(purF) was locked at its trough level.

163 EVR trough levels >8 ng/mL were significantly associated wit

164 dnDSA had a higher proportion of tacrolimus trough levels <5 ng/ml, which continued to be significan

165 and 2927 mg/y [IQR, 2377 to 3667 mg/y]) and trough levels (4.2 microg/mL [IQR, 2.6 to 5.8 microg/mL]

166 ents not infected with HIV, tacrolimus (TAC) trough levels (C0) or cyclosporine (CsA) drawn at C0 or

167 We compared maximum 12-hr tacrolimus trough levels (MaxC0) and dose-adjusted MaxC0 in 12 case

168 hich correlated with undetectable adalimumab trough levels (P = 0.014).

169 s observed between AAA titers and adalimumab trough levels (P = 0.2).Concomitant immunosuppression di

170 and 24 h after reperfusion), and tacrolimus (trough levels 8-12 ng/mL) was used for maintenance immun

171 ombination therapies including MMF, at serum trough levels and higher, are toxic for the human bronch

172 Tacrolimus trough levels and laboratory values were closely monitor

173 nDSA) development correlates with tacrolimus trough levels and the recipient's individualized alloimm

174 that HLA-DR/DQ eplet mismatch and tacrolimus trough levels are independent predictors of dnDSA develo

175 higher MMF exposure and elevated tacrolimus trough levels at M3.

176 Mean trough levels at week 24 in the IV infusion series of 30

177 TAC trough levels at week two posttransplant were significan

178 sttransplant year, with (1) at least 3 blood trough levels available to calculate coefficient of vari

179 initiated, the TAC dosage was skipped until trough levels began to decline; it was then administered

180 We analyzed the frequency of tacrolimus trough levels below a series of thresholds <6 ng/ml and

181 nversion tacrolimus dose at each visit; mean trough levels between groups were similar.

182 bulation), hospital discharge before initial trough levels could be drawn, or incorrect timing of tro

183 ant recipients with 50,011 serial tacrolimus trough levels had HLA-DR/DQ eplet mismatch determined us

184 Mean tacrolimus trough levels in the 6 months before dnDSA development w

185 ariable analysis, high calcineurin inhibitor trough levels in the month before diagnosis (odds ratio

186 Trough levels increased from 45 to 132 ng/ml (P<0.001).

187 ther increased to 6045 ng h/ml (P=0.03), and trough levels increased to 218 ng/ml (P=0.03), above the

188 The C1-INH trough levels increased with C1-INH treatment.

189 te rejection before month 3 (M3), tacrolimus trough levels more than 10 ng/mL, and M3 AUC0-12 hr more

190 Sirolimus was increased to maintain trough levels of 12-15 ng/mL.

191 A therapeutic range of adalimumab trough levels of 3.51 mg/L to 7.00 mg/L, which correspon

192 g at 3mg/m(2) /day (titrated to target blood trough levels of 5-15ng/ml).

193 ensitivity to PEGasparaginase had serum mean trough levels of 899 U/L.

194 nt between mice UV-irradiated during peak or trough levels of cyclosporine in the blood.

195 Patients were closely monitored for trough levels of immunosuppressive agents, laboratory va

196 Patients with very low trough levels of less than 4 g/L had poor clinical outco

197 Pronounced elevations in trough levels of nitric oxide metabolites occurred with

198 stem recovered bacteria only in bottles with trough levels of piperacillin-tazobactam.

199 re maintained on tacrolimus monotherapy with trough levels ranging between 4 and 12 ng/mL.

200 nts on ritonavir-containing cART and raising trough levels to achieve an exposure equivalent to HIV-n

201 to correlate the risk of proteinuria to EVR trough levels up to 24 months posttransplant.

202 ) than preconversion tacrolimus dose; target trough levels were 4-15 ng/mL.

203 L had poor clinical outcomes, whereas higher trough levels were associated with a reduced frequency o

204 Deviations in trough levels were avoided, thus preventing any clinical

205 ance: In this study, subprophylactic anti-Xa trough levels were common in trauma patients.

206 Baseline characteristics and mean tacrolimus trough levels were comparable between arms.

207 Overall, adalimumab trough levels were higher in responder patients.

208 Exposures: Anti-Xa trough levels were monitored in patients in the adjustme

209 Tacrolimus trough levels were readily achieved posttransplant; init

210 ted in HIV-negative recipients, when similar trough levels were targeted.

211 ed on LCP-Tacro once-daily for days 8 to 21; trough levels were to be maintained between 5 and 15 ng/

212 icates that certain PK parameters, including trough levels, are correlated with clinical outcomes for

213 Therapeutic monitoring is based on mTORi trough levels, which do not necessarily reflect biologic

214 evels could be drawn, or incorrect timing of trough levels.

215 with lower Tac, but not CsA, dose-normalized trough levels.

216 is clinically useful even in the absence of trough levels.

217 ll P<0.001) but did not correlate with mTORi trough levels.

218 LCPT requires lower doses to achieve target trough levels.

219 on between LCP-Tacro tacrolimus exposure and trough levels.

220 tacept with lowered tacrolimus and sirolimus trough levels.

221 us were necessary for maintaining sufficient trough levels.

222 meibomian lipid films (MLF) using a Langmuir trough (LT) and a Brewster angle microscope (BAM).

223 lthough the permeability of the sandy Nankai Trough materials are higher than that of the clayey mate

224 may determine whether a patient experiences trough-max or peak-max PAC, and the thalamus is a critic

225 determinant of whether the thalamus exhibits trough-max PAC, which is associated with lower propofol

226 ygon, coalescent low center polygon, polygon trough, meadow, ponds, rivers, and lakes, to determine t

227 in the peak month (April) compared with the trough month (November) (odds ratio, 1.24; 95% CI, 1.10-

228 the peak month, compared with November, the trough month.

229 30 m on the continental slope of the Rockall Trough, Northeast Atlantic, to compare changes in fracti

230 Trough OC levels were higher in the 150-mg group (501.0

231 ration (median, 38 ms) preferentially at the trough of both CA1 theta and slow irregular oscillations

232 pted Bmal1-knockout mice are locked into the trough of insulin action and lack rhythmicity in insulin

233 suppression was systematically embedded in a trough of oscillations of contrast sensitivity that fluc

234 In contrast, ripples occurring at the trough of their SPWs relate to weaker neocortical up-reg

235 ding and retrieval occur during the peak and trough of theta, respectively, and support the theory th

236 ormance when inhibition was triggered by the trough of theta.

237 it maximum alpha power at either the peak or trough of this SWO; this implies the thalamus may be the

238 imple cell's spikes tended to occur near the troughs of the complex cell's V(m) fluctuations and were

239 t, both cell types fire cooperatively at the troughs of theta oscillations but with different frequen

240 On the basis of the deep absorption trough on the blue side of the Lyman-alpha emission line

241 s using the position of the signal peaks and troughs on longitudinal reflectivity profiles.

242 mplitude of the inspiratory peak, expiratory trough or expiratory peak of sSNA in either group, but r

243 Plasma steady-state trough oseltamivir carboxylate (OC) concentration was me

244 The formation of the monsoon trough over Indo-Gangetic plain during the active period

245 y pressurized fluid is greater at the Nankai Trough owing to higher friction, although initially over

246 argeted mutants of Rsn-2, using the Langmuir trough, pendant drop tensiometry, and circular dichroism

247 Antiretroviral trough plasma concentrations (C12h) were determined usin

248 hole blood containing the peak, midpoint, or trough plasma concentrations for meropenem, ceftolozane-

249 Geometric mean trough plasma concentrations were 0.302 mug/mL (95% CI 0

250 Doses were adjusted to obtain a trough plasma level of at least 50 ng per milliliter.

251 The primary end point was the trough plasma level of dabigatran.

252 Concomitant high vancomycin trough plasma levels had been observed in each patient.

253 The mean trough plasma levels of C1-INH functional activity, C1-I

254 r 60 mg bid achieved high levels of peak and trough platelet inhibition in nearly all patients, simil

255 On Bylot, ice-wedge trough ponds showed significantly higher MeHg (0.3-2.2 n

256 tion, played a major role in determining the trough positions of simulated binaural phase-response cu

257 nd permafrost samples from center, ridge and trough positions of water-saturated low-centered polygon

258 TNF was administered locally into a trough, providing local TNF treatment of a cortical area

259 re found to in turn cluster ripples in their troughs, providing fine-tuned temporal frames for the hy

260 rgy backup and cooling options for parabolic trough (PT) concentrated solar power have technical, eco

261 to hemipelagic sediments from the Laurentian Trough (Quebec, Canada), we found that soluble Mn(III),

262 Dose adjustments were done to attain target trough ranges during a 6-week titration period, and as n

263 injection with CSL830 showed a lower peak-to-trough ratio and more consistent exposures.

264 ed pharmacokinetic profile of a high peak to trough ratio and short half-life in humans.

265 implications for dosing regimen and peak-to-trough ratio at the steady state.

266 molgus monkey that showed a very low peak-to-trough ratio.

267 initially overpressured fluid at the Nankai Trough restrains the fault weakening.

268 Non-fasting peak and trough samples of maternal plasma and breast milk were o

269 r the maternal DOT PrEP dose, while maternal trough samples were obtained at the end of the PrEP dosi

270 The primary endpoint was trough serum concentration at cycle five, with a non-inf

271 At cycle five, the geometric mean trough serum concentration in patients given subcutaneou

272 hilst at 19 microg.mL(-1) (a clinical target trough serum concentration), vancomycin was mainly monom

273 subcutaneous rituximab 1600 mg would achieve trough serum concentrations that were non-inferior to th

274 ide, subcutaneous rituximab 1600 mg achieved trough serum concentrations that were pharmacokineticall

275 acebo twice daily, with the dosage guided by trough serum levels.

276 Regarding to RVA results, peak, breakdown, trough, setback, and final viscosities of native starch

277 erred theta firing phase closer to the theta trough, shifting the encoding-retrieval balance even fur

278 lls and interneurons spiked at PV-inhibition troughs, similar to CA1 cells during spontaneous theta o

279 g hippocampal ripples within their excitable troughs, stimulation in-phase with the slow oscillation

280 e intervals from midwinter peak crowding and trough sunlight to sequential peaks in vitamin D deficie

281 During the weeks following peak crowding and trough sunlight, there was a midwinter peak in vitamin D

282 The decrease was related to predose trough tacrolimus concentrations or doses and disappeare

283 of in situ atomic force microscopy, Langmuir trough techniques, and vesicle permeability assays were

284 ecline from an observed peak to a subsequent trough, tends to severely overestimate the frequency and

285 the organic-rich soils of polygon center and trough than the relatively drier ridge soils.

286 elements associate head-to-tail, creating a trough that cradles two c-di-AMP molecules making quasi-

287 r was associated with a mean decrease in UVR trough to subsequent relapse peak lag of 28.5 days (95%

288 amplitude (AMPP-T ) at nine stations, and in trough-to-peak amplitude (AMPT-P ) at eight stations ove

289 f neurons with intermediate spike durations (trough-to-peak approximately 350 mus after high-pass fil

290 13.0 to 250.0) for emtricitabine, reflecting trough-to-peak breast milk concentration ratios of 1.0 f

291 nofovir and emtricitabine (respective median trough-to-peak concentration ratio ~1), demonstrating th

292 loading, p.E161K carriers displayed a higher trough urinary pH (5.34 versus 4.89; P=0.01) than wild-t

293 on of pyramidal cell assemblies at the theta trough via disinhibition.

294 Peak, breakdown and trough viscosity values of the amylose-lipid complexed s

295 ) of mRNA into immunodeficient mice maintain trough VRC01 levels above 40 mug ml(-1).

296 Correlograms with a peak or trough were taken as evidence for excitatory or inhibito

297 Subprophylactic anti-Xa troughs were noted in 73 of 87 patients (83.9%) in the a

298 -September, which was 4-fold higher than the trough, which occurred during January-March.

299 Mean trough whole blood tacrolimus levels were at their lowes

300 ating that higher positive charges (measured trough zeta potential) in the gelatin solution tended to