ライフサイエンスコーパス: trypsin-like serine protease

1 at Dps should be a substrate for thrombin, a trypsin-like serine protease.

2 is an epithelial-derived, integral membrane, trypsin-like serine protease.

3 t had an inhibitor profile consistent with a trypsin-like serine protease.

4 inhibitory activity toward a large number of trypsin-like serine proteases.

5 ubstrate interaction in the entire family of trypsin-like serine proteases.

6 nal KD1 and C-terminal KD2) known to inhibit trypsin-like serine proteases.

7 n kinases, lactate/malate dehydrogenases and trypsin-like serine proteases.

8 for the inhibition of fXa relative to other trypsin-like serine proteases.

9 ified to be Asp-627 by comparison with other trypsin-like serine proteases.

10 bstrate position P1 are conserved with other trypsin-like serine proteases.

11 The trypsin-like serine proteases(1) that comprise drug targ

12 A nonselective inhibitor of trypsin-like serine proteases, 2-(2-hydroxybiphenyl-3-yl

13 We use insights from the canonical trypsin-like serine protease activation mechanism to sho

14 activated receptor-2 (PAR-2) is activated by trypsin-like serine proteases and can promote cell migra

15 that forms inhibitor complexes with several trypsin-like serine proteases and is required for mouse

16 omplex of coagulation factor VIIa (FVIIa), a trypsin-like serine protease, and membrane-bound tissue

17 with similar potency, whereas PC2, PC7, and trypsin-like serine proteases are poorly affected.

18 The catalytic activity of the trypsin-like serine protease coagulation factor VIIa is

19 ot appreciably inhibit 12 of the 14 examined trypsin-like serine proteases, consistent with its TF.FV

20 hand, Tropomyosin, CAP, Profilin, Lipocalin, Trypsin-like serine protease, Cupin, BetV1, Expansin and

21 The zymogen and mature enzyme forms of trypsin-like serine proteases exhibit a wide range of ac

22 However, the paucity of the S1 chymotrypsin/trypsin-like serine protease family in the I. scapularis

23 found in catalytic triads of enzymes in the trypsin-like serine protease family, and SplB and SplC w

24 boxyl-terminal region with similarity to the trypsin-like serine proteases, four tandem cysteine-rich

25 Although trypsin-like serine proteases have flexible surface-expo

26 nd dog, together with selectivity over other trypsin-like serine proteases, identified 1f as a candid

27 ms and conformational flexibility of uPA and trypsin-like serine proteases in general.

28 lar range, and their potency against related trypsin-like serine proteases including trypsin itself c

29 R-2 is activated via proteolytic cleavage by trypsin-like serine proteases, including kallikrein-5 (K

30 This activity of EKsolCorin was inhibited by trypsin-like serine protease inhibitors but not inhibito

31 In summation, novel and potent trypsin-like serine protease inhibitors possessing a uni

32 The trypsin-like serine protease marapsin is a member of the

33 Granzymes are trypsin-like serine proteases mediating apoptotic cell d

34 The trypsin-like serine protease plasmin is a target for the

35 irway epithelial cDNA library identified two trypsin-like serine proteases (prostasin and TMPRSS2) th

36 beta-Tryptase is a trypsin-like serine protease stored in mast cell secreto

37 n factor VIIa is an allosterically regulated trypsin-like serine protease that initiates the coagulat

38 Prostasin is a trypsin-like serine protease that is glycosylphosphatidy

39 Testisin is a unique trypsin-like serine protease that is tethered to the ext

40 ), mesothelin (a cancer marker), marapsin (a trypsin-like serine protease that may control cell growt

41 Factor Xa (FXa) is a trypsin-like serine protease that plays a key role in bl

42 Factor Xa (FXa) is a trypsin-like serine protease that plays a key role in th

43 upstream coagulation enzymes are homologous trypsin-like serine proteases that typically function in

44 eas it has poor activity against the related trypsin-like serine proteases thrombin, factor Xa, or ac

45 and selectivity with respect to the related trypsin-like serine proteases (thrombin, tPA, FXa, plasm

46 cidin and kallikrein 5 (KLK5), a predominant trypsin-like serine protease (TLSP) in the stratum corne

47 The trypsin-like serine protease, urokinase-type plasminogen

48 po crystal structure of HRV-14 3CP and other trypsin-like serine proteases were constructed to approx

49 Matriptase, a trypsin-like serine protease, which may be involved in t

50 Factor D is a trypsin-like serine protease with a narrow specificity f

51 Blood coagulation factor IXa (fIXa) is a trypsin-like serine protease with low inherent activity

52 Matriptase, a trypsin-like serine protease with two potential regulato

53 were determined for nearly all other tested trypsin-like serine proteases, with the exception of try