ライフサイエンスコーパス: tryptophanyl-tRNA

1 nitial amber suppressor version of the yeast tryptophanyl tRNA.

2 tion catalyzed by wild-type Escherichia coli tryptophanyl-tRNA synthe-tase (TrpRS) have now been inve

3 An auxiliary tryptophanyl tRNA synthetase (drTrpRS II) that interacts

4 iodurans (deiNOS) associates with an unusual tryptophanyl tRNA synthetase (TrpRS).

5 ted induction of the gene encoding the human tryptophanyl tRNA synthetase (WRS) results in the produc

6 netic codes, we have developed an orthogonal tryptophanyl tRNA synthetase and tRNA pair, derived from

7 aromatic amino acids; and cells harboring a tryptophanyl tRNA synthetase mutation conferring tempera

8 es the first step of protein synthesis-human tryptophanyl-tRNA synthetase (T2-TrpRS) has potent anti-

9 ccus radiodurans NOS (deiNOS) and an unusual tryptophanyl-tRNA synthetase (TrpRS II) catalyzes the re

10 al structures of Bacillus stearothermophilus tryptophanyl-tRNA synthetase (TrpRS) afford evidence tha

11 r example, an alternative splice fragment of tryptophanyl-tRNA synthetase (TrpRS) and a similar natur

12 Two forms of human tryptophanyl-tRNA synthetase (TrpRS) are produced in viv

13 that competes with tryptophan for binding to tryptophanyl-tRNA synthetase (TrpRS) enzymes.

14 c.770A > G (p.His257Arg), in the cytoplasmic tryptophanyl-tRNA synthetase (TrpRS) gene (WARS) that co

15 Binding ATP to tryptophanyl-tRNA synthetase (TrpRS) in a catalytically

16 Tryptophanyl-tRNA synthetase (TrpRS) is a close homologu

17 Human tryptophanyl-tRNA synthetase (TrpRS) is active in transl

18 by contemporary Bacillus stearothermophilus tryptophanyl-tRNA synthetase (TrpRS) over that of TrpRS

19 We have investigated the tryptophanyl-tRNA synthetase (TrpRS) purified from six a

20 Tryptophanyl-tRNA Synthetase (TrpRS) Urzyme (fragments A

21 As observed for the tryptophanyl-tRNA synthetase (TrpRS) Urzyme, these fragm

22 the aromatic amino acid permease (aroP) and tryptophanyl-tRNA synthetase (trpS) contained several am

23 Mitochondrial tryptophanyl-tRNA synthetase (Wars2), encoding an L53F p

24 Furthermore, we show that E. coli tryptophanyl-tRNA synthetase also displays tRNA-dependen

25 We deleted the anticodon binding domain from tryptophanyl-tRNA synthetase and fused the discontinuous

26 we report the co-crystal structure of human tryptophanyl-tRNA synthetase and tRNATrp.

27 an activation by Bacillus stearothermophilus tryptophanyl-tRNA synthetase falls asymptotically to a p

28 The crystal structure of a highly homologous tryptophanyl-tRNA synthetase from Bacillus stearothermop

29 ption of the auxiliary, antibiotic-resistant tryptophanyl-tRNA synthetase gene (trpRS1) in Streptomyc

30 RNATrp, and WRS-85D is likely to be the only tryptophanyl-tRNA synthetase gene in Drosophila.

31 la embryonic salivary gland, we identified a tryptophanyl-tRNA synthetase gene that maps to cytologic

32 uss the potential noncanonical activities of tryptophanyl-tRNA synthetase in immune response and regu

33 The bacterial tryptophanyl-tRNA synthetase inhibitor indolmycin featur

34 id activation by Bacillus stearothermophilus tryptophanyl-tRNA synthetase involves three allosteric s

35 A potential polymorphic variant of human tryptophanyl-tRNA synthetase is shown here to sequester

36 e our preliminary description of the class I tryptophanyl-tRNA synthetase minimal catalytic domain wi

37 subtilis containing a temperature-sensitive tryptophanyl-tRNA synthetase produce elevated levels of

38 While kinetic analysis of the tryptophanyl-tRNA synthetase suggests discrimination aga

39 A crystal structure of human tryptophanyl-tRNA synthetase was solved at 2.1 A with a

40 The structure of yeast tryptophanyl-tRNA synthetase was solved to 1.8 A by usin

41 ions were mapped to the trpS locus (encoding tryptophanyl-tRNA synthetase) have been previously isola

42 enzymes, tyrosyl-tRNA synthetase (TyrRS) and tryptophanyl-tRNA synthetase, connect protein synthesis

43 ining a temperature-sensitive mutant form of tryptophanyl-tRNA synthetase, encoded by the trpS1 allel

44 ese nucleotides for recognition by the plant tryptophanyl-tRNA synthetase.

45 an orthogonal promoter and to reengineer the tryptophanyl tRNA-synthetase:suppressor tRNA pair from S

46 Indoleamine-2,3-dioxygenase (IDO) and tryptophanyl-tRNA-synthetase (TTS) are interferon-gamma

47 Recent work suggests that human tyrosyl- and tryptophanyl-tRNA synthetases (TrpRS) link protein synth

48 he possibility that present day tyrosyl- and tryptophanyl-tRNA synthetases appeared after the separat

49 Ij particular, the eukaryotic tyrosyl- and tryptophanyl-tRNA synthetases are more related to each o

50 s shared by all tyrosyl-tRNA synthetases and tryptophanyl-tRNA synthetases for amino acid discriminat

51 ts of the closely related human tyrosyl- and tryptophanyl-tRNA synthetases were discovered to be acti

52 (another antibiotic that inhibits bacterial tryptophanyl-tRNA synthetases) and that its transcriptio

53 reptomyces coelicolor has two genes encoding tryptophanyl-tRNA synthetases, one of which (trpRS1) is

54 ycin, two antibiotics that inhibit bacterial tryptophanyl-tRNA synthetases.

55 at shows an unusual picture for tyrosyl- and tryptophanyl-tRNA synthetases.

56 Kinetoplastids encode a single nuclear tryptophanyl tRNA that contains a CCA anticodon able to