ライフサイエンスコーパス: tryptophanyl-tRNA synthetase

1 ese nucleotides for recognition by the plant tryptophanyl-tRNA synthetase.

2 at shows an unusual picture for tyrosyl- and tryptophanyl-tRNA synthetases.

3 ycin, two antibiotics that inhibit bacterial tryptophanyl-tRNA synthetases.

4 Furthermore, we show that E. coli tryptophanyl-tRNA synthetase also displays tRNA-dependen

5 netic codes, we have developed an orthogonal tryptophanyl tRNA synthetase and tRNA pair, derived from

6 We deleted the anticodon binding domain from tryptophanyl-tRNA synthetase and fused the discontinuous

7 we report the co-crystal structure of human tryptophanyl-tRNA synthetase and tRNATrp.

8 (another antibiotic that inhibits bacterial tryptophanyl-tRNA synthetases) and that its transcriptio

9 he possibility that present day tyrosyl- and tryptophanyl-tRNA synthetases appeared after the separat

10 Ij particular, the eukaryotic tyrosyl- and tryptophanyl-tRNA synthetases are more related to each o

11 enzymes, tyrosyl-tRNA synthetase (TyrRS) and tryptophanyl-tRNA synthetase, connect protein synthesis

12 An auxiliary tryptophanyl tRNA synthetase (drTrpRS II) that interacts

13 ining a temperature-sensitive mutant form of tryptophanyl-tRNA synthetase, encoded by the trpS1 allel

14 an activation by Bacillus stearothermophilus tryptophanyl-tRNA synthetase falls asymptotically to a p

15 s shared by all tyrosyl-tRNA synthetases and tryptophanyl-tRNA synthetases for amino acid discriminat

16 The crystal structure of a highly homologous tryptophanyl-tRNA synthetase from Bacillus stearothermop

17 ption of the auxiliary, antibiotic-resistant tryptophanyl-tRNA synthetase gene (trpRS1) in Streptomyc

18 RNATrp, and WRS-85D is likely to be the only tryptophanyl-tRNA synthetase gene in Drosophila.

19 la embryonic salivary gland, we identified a tryptophanyl-tRNA synthetase gene that maps to cytologic

20 ions were mapped to the trpS locus (encoding tryptophanyl-tRNA synthetase) have been previously isola

21 uss the potential noncanonical activities of tryptophanyl-tRNA synthetase in immune response and regu

22 The bacterial tryptophanyl-tRNA synthetase inhibitor indolmycin featur

23 id activation by Bacillus stearothermophilus tryptophanyl-tRNA synthetase involves three allosteric s

24 A potential polymorphic variant of human tryptophanyl-tRNA synthetase is shown here to sequester

25 e our preliminary description of the class I tryptophanyl-tRNA synthetase minimal catalytic domain wi

26 aromatic amino acids; and cells harboring a tryptophanyl tRNA synthetase mutation conferring tempera

27 reptomyces coelicolor has two genes encoding tryptophanyl-tRNA synthetases, one of which (trpRS1) is

28 subtilis containing a temperature-sensitive tryptophanyl-tRNA synthetase produce elevated levels of

29 While kinetic analysis of the tryptophanyl-tRNA synthetase suggests discrimination aga

30 an orthogonal promoter and to reengineer the tryptophanyl tRNA-synthetase:suppressor tRNA pair from S

31 es the first step of protein synthesis-human tryptophanyl-tRNA synthetase (T2-TrpRS) has potent anti-

32 iodurans (deiNOS) associates with an unusual tryptophanyl tRNA synthetase (TrpRS).

33 ccus radiodurans NOS (deiNOS) and an unusual tryptophanyl-tRNA synthetase (TrpRS II) catalyzes the re

34 al structures of Bacillus stearothermophilus tryptophanyl-tRNA synthetase (TrpRS) afford evidence tha

35 r example, an alternative splice fragment of tryptophanyl-tRNA synthetase (TrpRS) and a similar natur

36 Two forms of human tryptophanyl-tRNA synthetase (TrpRS) are produced in viv

37 that competes with tryptophan for binding to tryptophanyl-tRNA synthetase (TrpRS) enzymes.

38 c.770A > G (p.His257Arg), in the cytoplasmic tryptophanyl-tRNA synthetase (TrpRS) gene (WARS) that co

39 Binding ATP to tryptophanyl-tRNA synthetase (TrpRS) in a catalytically

40 Tryptophanyl-tRNA synthetase (TrpRS) is a close homologu

41 Human tryptophanyl-tRNA synthetase (TrpRS) is active in transl

42 by contemporary Bacillus stearothermophilus tryptophanyl-tRNA synthetase (TrpRS) over that of TrpRS

43 We have investigated the tryptophanyl-tRNA synthetase (TrpRS) purified from six a

44 Tryptophanyl-tRNA Synthetase (TrpRS) Urzyme (fragments A

45 As observed for the tryptophanyl-tRNA synthetase (TrpRS) Urzyme, these fragm

46 Recent work suggests that human tyrosyl- and tryptophanyl-tRNA synthetases (TrpRS) link protein synth

47 the aromatic amino acid permease (aroP) and tryptophanyl-tRNA synthetase (trpS) contained several am

48 Indoleamine-2,3-dioxygenase (IDO) and tryptophanyl-tRNA-synthetase (TTS) are interferon-gamma

49 Mitochondrial tryptophanyl-tRNA synthetase (Wars2), encoding an L53F p

50 A crystal structure of human tryptophanyl-tRNA synthetase was solved at 2.1 A with a

51 The structure of yeast tryptophanyl-tRNA synthetase was solved to 1.8 A by usin

52 ts of the closely related human tyrosyl- and tryptophanyl-tRNA synthetases were discovered to be acti

53 ted induction of the gene encoding the human tryptophanyl tRNA synthetase (WRS) results in the produc