ライフサイエンスコーパス: tubulitis

1 1 (0-10% interstitial inflammation with mild tubulitis).

2 rstitial inflammation (i > 0 with or without tubulitis).

3 e Banff-scored interstitial inflammation and tubulitis.

4 nt (hazard ratio 1.1, CI: 1.0-1.2 per year), tubulitis (1.5, 1.3-1.8) and microvasculature injury (2.

5 s interstitial/perivascular infiltration and tubulitis 3 and 5 days after Tx, and a lower level of IL

6 and tubular atrophy, n = 52), and borderline tubulitis (3.3, [1.3, 4.9], n = 36).

7 ic glomerulitis, 55% versus 4%; neutrophilic tubulitis, 55% versus 9%; severe ATI, 75% versus 9%; and

8 Neutrophilic tubulitis accompanied by intratubular neutrophil cluster

9 Neutrophilic tubulitis accompanied by neutrophil clusters in the tubu

10 with AR and also associated with severity of tubulitis, among the top 15 SNPs.

11 rred with a threshold of > or =1 tubule with tubulitis and > or =5% cortex with interstitial infiltra

12 reased graft function, and a higher grade of tubulitis and inflammation in AMR are negative predictor

13 UTI in biopsies with concurrent neutrophilic tubulitis and PTC C4d staining.

14 a, the thresholds for number of tubules with tubulitis and the percent infiltrate were varied, and th

15 linear regression model, both CD3(+) T cell tubulitis and tubular atrophy independently associated w

16 days showed significantly reduced scores for tubulitis and vasculitis in the grafts of these recipien

17 d CD8 interstitial mononuclear inflammation, tubulitis, and endarteritis.

18 group showed more interstitial inflammation, tubulitis, and glomerulitis.

19 the extent of the interstitial infiltrate or tubulitis, are correlated with response to antirejection

20 expression of CD103 was examined in situ in tubulitis associated with acute rejection.

21 ular infiltrates without overt vasculitis or tubulitis, but these infiltrates disappeared without tre

22 The v-lesions with minimal or high-grade tubulitis displayed similar graft survival (72.7% vs. 72

23 racterized by a T cell (CD25(+)) infiltrate, tubulitis, endothelialitis and glomerulitis, and anti-do

24 rtex, a total of at least three tubules with tubulitis in 10 consecutive high-power fields from the m

25 grafts showed interstitial inflammation with tubulitis in 7 of 10 (70%) patients; in 3 of 10 (30%) pa

26 sfying Banff thresholds for inflammation and tubulitis in the presence of viruria but negative for BK

27 The SNPs associated with AR and severity of tubulitis in this study will need to be validated in ind

28 ma cell infiltration, as well as scoring for tubulitis, interstitial inflammation, and glomerulitis.

29 al fibrosis scores in early AMR patients and tubulitis, interstitial inflammation, g, ptc, and C4d in

30 roved mean scores for acute Banff components tubulitis, interstitial inflammation, g, ptc, g + ptc, C

31 Tubulitis is a defining feature for the diagnosis and ma

32 Tubulitis is a defining feature of renal allograft rejec

33 ormally show no lymphocyte infiltration, but tubulitis is a feature of renal allograft rejection with

34 The extent of tubulitis or of the interstitial infiltrate did not corr

35 rs independently associated with severity of tubulitis (P<0.05).

36 group was significantly associated with less tubulitis (P=0.0021), and more chronic allograft arterio

37 ion score (2.6+/-0.1 to 1.3+/-0.1, P<0.001), tubulitis score (2.6+/-0.1 to 1.1+/-0.1, P<0.001), and s

38 + to CD8+ cells increased significantly with tubulitis score (P values 0.005, 0.009, and 0.02, respec

39 n tubules also increasing significantly with tubulitis score (P=0.034).

40 bles at the time of index TCMR, although the tubulitis scores tended to be higher (P = 0.079).

41 ed 15 novel SNPs associated with severity of tubulitis scores, after adjusting for transplant center

42 ance treatment with immunosuppressive drugs, tubulitis still occurs and can lead to structural kidney

43 (10-25% interstitial inflammation with mild tubulitis) to i0t1 (0-10% interstitial inflammation with

44 imes exaggerating Banff i in the presence of tubulitis, to reach a diagnosis of Borderline.

45 CD8+ T cell tubulitis was especially associated with progressive cha

46 Mononuclear cell tubulitis was more common in the C4d(-) group (70% versu

47 f simultaneous C4d staining and neutrophilic tubulitis were correlated with urine culture (U/C) resul

48 Given the strong association of tubulitis with clinical rejection, these data are consis