ライフサイエンスコーパス: tumor cell line

1 ioxidant potential and cytotoxic activity in tumor cell lines).

2 rectal cancer patients and from a metastatic tumor cell line.

3 on and apoptosis induction in a human breast tumor cell line.

4 candidate microRNA biomarkers in a rat solid tumor cell line.

5 glioblastoma and atypical teratoid rhabdoid tumor cell lines.

6 CI panel of 60 human hematological and solid tumor cell lines.

7 cytostatic activity in a range of different tumor cell lines.

8 reast and skin) as well as on the surface of tumor cell lines.

9 enesis and development of drug resistance in tumor cell lines.

10 ected by Western blot analysis of a group of tumor cell lines.

11 rties and replication kinetics on a panel of tumor cell lines.

12 tion of their selectivity against a range of tumor cell lines.

13 umors from patients are preferable to clonal tumor cell lines.

14 he expression of beta-Pix in both HUVECs and tumor cell lines.

15 ased production of PGE(2) and/or IL-6 by the tumor cell lines.

16 on of pMEK and proliferation) in KRAS mutant tumor cell lines.

17 ive activity against a large number of human tumor cell lines.

18 antitumor activity against a panel of solid tumor cell lines.

19 vitro against Hek293, Jurkat, K562, and A549 tumor cell lines.

20 -transduced cells against leukemia and solid tumor cell lines.

21 growth inhibition of both leukemia and solid tumor cell lines.

22 s as well as in human and mouse corticotroph tumor cell lines.

23 ation in both Xenopus egg extracts and human tumor cell lines.

24 ive activity was evaluated against two human tumor cell lines.

25 monitor K-Ras inhibition in a panel of human tumor cell lines.

26 wing low nanomolar cytotoxicity toward human tumor cell lines.

27 in several murine and human lymphoid-derived tumor cell lines.

28 erapeutic strategy by using a panel of Wilms tumor cell lines.

29 horylation and activation of SIAH2 in breast tumor cell lines.

30 es and CA in patient tumors, xenografts, and tumor cell lines.

31 egulated under conditions of hypoxia in many tumor cell lines.

32 disease progression using EGFR-mutant human tumor cell lines.

33 totoxic efficacy of C7H2 in a panel of human tumor cell lines.

34 s of 55 primary BLC cases and 17 BLC-derived tumor cell lines.

35 ivating protein showing high selectivity for tumor cell lines.

36 nt for alkylation damage resistance in these tumor cell lines.

37 frequently reduced in pancreatic tumors and tumor cell lines.

38 ding proteinbeta (C/EBPbeta) in a variety of tumor cell lines.

39 sion and evaluated their relationships using tumor cell lines.

40 of their cytotoxicity against several human tumor cell lines.

41 yrimidines with potent activity against TNBC tumor cell lines.

42 ht provide a novel method for the culture of tumor cell lines.

43 ny formation assays, relative to control Myc tumor cell lines.

44 d endothelial cells (ECs) and in a subset of tumor cell lines.

45 1beta was expressed at higher levels in most tumor cell lines.

46 inhibitor that is active in taxane-resistant tumor cell lines.

47 reased gene copy number, in human tumors and tumor cell lines.

48 igate the expression and function of EpoR in tumor cell lines.

49 , through a p53-independent process in solid tumor cell lines.

50 EMP2 expression in both patient samples and tumor cell lines.

51 r cell types, de-stabilized EGFR in multiple tumor cell lines.

52 in SS tumor cells with those in >130 non-SS tumor cell lines.

53 heir high cytotoxicity toward LNCaP and PC-3 tumor cell lines.

54 ms and efficiencies of killing of a range of tumor cell lines.

55 ntrol patients as well as 12 UM and 64 other tumor cell lines.

56 ey have improved cytotoxic functions against tumor cell lines.

57 ular uptake of 4-7-[(18)F]FTrps in different tumor cell lines.

58 ted potent antitumor activity against breast tumor cell lines.

59 complex with cytotoxic activity against some tumor cell lines.

60 ity (>10 muM) when evaluated against several tumor cell lines.

61 s determined in human pancreatic tissues and tumor cell lines.

62 cells from doxorubicin-resistant metastatic tumors (cell line 4T1-R).

63 and (18)F-(2S,4R)4F-GLU was determined in 3 tumor cell lines (9L, SF188, and PC-3) at selected time

64 demonstrated with inhibitors 9 and 14 in two tumor cell lines (A549, D54).

65 n28 can reprogram the Ewing's sarcoma family tumor cell line A673 to produce stem cell-like colonies

66 In a MCL-1 dependent human tumor cell line, administration of compound 30b rapidly

67 erative activities against a panel of tested tumor cell lines along with a better safety ratio of app

68 Tumor growth varies by tumor cell line and mouse strain used.

69 y (GI50 10-66.9 nM) against the NCI 60 human tumor cell line and significant potency against tubulin

70 recurrently expressed in a number of breast tumor cell lines and a clinical tumor sample.

71 ed efficiency in inhibiting proliferation in tumor cell lines and a rat xenograft model.

72 s display cytotoxic activity against several tumor cell lines and activated, but not resting, immune

73 ion is down-regulated in grade IV astrocytic tumor cell lines and also in clinical cases of the disea

74 ed from mouse tissues and primary pancreatic tumor cell lines and analyzed by reverse-transcription p

75 ds have anticancer activity in several solid tumor cell lines and are less toxic in a normal human lu

76 usters from the database of the NCI-60 human tumor cell lines and associated each cluster with functi

77 were activated by and destroyed ErbB(+) EOC tumor cell lines and autologous tumor cultures.

78 Here we screened 12 human tumor cell lines and identified 3 that are growth inhibi

79 COPZ1) was down-regulated in the majority of tumor cell lines and in clinical samples of different ca

80 on of a myofibroblast-like signature in both tumor cell lines and in metastatic tumor biopsies.

81 Some have subpicomolar IC50 values in human tumor cell lines and in primary chronic lymphocytic leuk

82 ed in primary human neuroblastoma tumors and tumor cell lines and is necessary for their in vitro and

83 w here that CD73 is widely expressed on many tumor cell lines and is upregulated in cancerous tissues

84 ession of MGL suppressed colony formation in tumor cell lines and knockdown of MGL resulted in increa

85 s, with 5- and 8-residue fragments formed in tumor cell lines and only the 8-residue fragment formed

86 Using both tumor cell lines and patient samples, we show that tumor

87 tion with the levels of MET protein in human tumor cell lines and patient-derived tumor materials.

88 nvasion, and metastasis, of both human colon tumor cell lines and primary human colon cancer tissue x

89 increases CD20 levels in established B-cell tumor cell lines and primary malignant cells.

90 Using tumor cell lines and primary patient samples representin

91 fic in vitro and ex vivo cytotoxicity toward tumor cell lines and primary tumor cells in the presence

92 stimulation and recognition of CD70-positive tumor cell lines and primary tumor cells, as shown by IF

93 Notably, the number of ALDH(hi) cells in tumor cell lines and primary tumors inversely correlated

94 ) is aberrantly overexpressed in human colon tumor cell lines and selectively required for their surv

95 e significant differences between pancreatic tumor cell lines and small intestinal cell lines, the di

96 cytolytic killing assays against a range of tumor cell lines and subsequent peptide epitope mapping

97 ammary epithelial cells compared with breast tumor cell lines and that estrogen receptor (ER)-positiv

98 ll-autonomous apoptotic growth inhibition of tumor cell lines and that growth inhibition is associate

99 on the gene expression profiles of 60 human tumor cell lines and the in vitro sensitivities of the c

100 ved ability to reduce the growth of multiple tumor cell lines and to inhibit ligand-induced IGF-1R si

101 igh in four MMTV-Hoxb7/Her2 transgenic mouse tumor cell lines and two breast cancer cell lines transf

102 ost human cell models of cancer are based on tumor cell lines and xenografts of primary tumor cells t

103 inase-3beta inhibition in several epithelial tumor cell lines, and by Snail1 overexpression in colore

104 from several different chromosomes in seven tumor cell lines, and characterized an unprecedented num

105 mRNA and protein isoforms in mouse tissues, tumor cell lines, and during terminal differentiation of

106 lity was observed in several mouse and human tumor cell lines, and knockdown of ATF4 significantly in

107 CXCL4L1 is also expressed in patient tumors, tumor cell lines, and murine xenografts, prompting a mor

108 ldehyde is highly cytotoxic to dox-resistant tumor cell lines, and that this benefit is absent in com

109 al-reporter genes were incorporated into all tumor cell lines, and their expression levels were confi

110 semination of various mammary and nonmammary tumor cell lines, and this prometastatic behavior is ass

111 -shaped nuclei in nontransformed cell lines, tumor cell lines, and tissues of FTI-treated mice.

112 ested by the National Cancer Institute Human Tumor Cell Line Anti-Cancer Drug Screen, and the NCI COM

113 Lastly, on the basis of the NCI human tumor cell line anticancer drug screen and the NCI COMPA

114 gands were characterized with the pancreatic tumor cell line AR42J in vitro, including assessment of

115 However, not all tumor cell lines are sensitive to statins, and clinical

116 .c.) implantation of a luciferase-expressing tumor cell line as a reporter.

117 inhibitory activity in a panel of different tumor cell lines as determined by analyses of cell viabi

118 pharmacotherapeutic studies using pancreatic tumor cell lines as models for small intestinal or 'carc

119 e in Notch3 expression was observed in human tumor cell lines as well as primary human breast cancer

120 itutively phosphorylated in several lymphoid tumor cell lines as well as primary leukemia and lymphom

121 in both macrophage-like VM-M3 and RAW 264.7 tumor cell lines as well as stimulated and unstimulated

122 n the substitution pattern as well as on the tumor cell line, as evidenced from the annexin V-FITC/PI

123 dies, we detected K-Ras4A protein in several tumor cell lines at a level equal to or greater than tha

124 Furthermore, 30 induced death in a panel of tumor cell lines at doses 5-50 times lower than an equit

125 icient antiproliferative effect on different tumor cell lines at low micromolar concentrations.

126 M060184 show antimitotic properties in human tumor cells lines at subnanomolar concentrations and dis

127 nts with the human pancreatic neuroendocrine tumor cell line BON-1 were performed at both 0 degrees C

128 vation of lytic infection occurs not only in tumor cell lines but also in freshly isolated B cells fr

129 protein synthesis and cell proliferation in tumor cell lines but not in normal fibroblasts.

130 E silencing enhanced the radiosensitivity of tumor cell lines but not normal cells.

131 Using human pancreatic tumor cell lines BxPC3 and Capan-1, which express Cx26 a

132 endently inhibited proliferation of numerous tumor cell lines by inducing the ATM cell cycle checkpoi

133 ayed for antiproliferative activity on human tumor cell lines by MTT assay, for antioxidant potential

134 s confirmed in an independent panel of human tumor cell lines carrying diverse genetic alterations.

135 otoxicity was determined in a panel of human tumor cell lines (CH1, SW480 and A549) by means of the M

136 e show that PDE10 is elevated in human colon tumor cell lines compared with normal colonocytes, as we

137 lantation model of an Erbb2-positive mammary tumor cell line confirmed the effect of Bcl3 in malignan

138 Here, we show that subpopulations of tumor cell lines constitutively expressing high levels o

139 A tumor cell line containing mutant p53 also revealed mass

140 Heterozygous deletion of NMNAT1 in lung tumor cell lines correlates with low expression level an

141 pro-proliferative role in an immortalized MB tumor cell line (DAOY).

142 In this study, we used a tumor cell line derived from a genetically engineered mo

143 145 and PC3 prostate cancer cells and a skin tumor cell line derived from EphA1/A2 knockout mice.

144 adenocarcinomas and was highly expressed in tumor cell lines derived from mice that develop metastat

145 senchymal transition (EMT) and metastasis in tumor cell lines derived from mice that develop metastat

146 r Institute (Bethesda, MD) on about 60 human tumor cell lines derived from nine cancer cell types.

147 endence on estrogen: Injection of ERalpha(+) tumor cell lines derived from such tumors into ovx or un

148 Mechanistic investigations in mammary tumor cell lines derived from wild-type or Trask-deficie

149 ed with guinea pig brain and human RPMI 8226 tumor cell lines differed slightly but showed the same t

150 The tumor cell lines displayed degradation rates statistical

151 r, when incubated with this agent many solid tumor cell lines do not undergo apoptosis.

152 subsequent challenge with an OVA-expressing tumor cell line, E.G7.

153 In addition, we found that oral cavity tumor cell lines (eg, UMSCC1 and UMSCC47) overexpressing

154 overexpression of Zpo2 in MMTV-PyMT mammary tumor cell lines enhances lung metastasis.

155 o be the most effective toward all the human tumor cell lines evaluated (PC3, DU145, 2008, C13, and L

156 y phosphorylation of peptide substrate, each tumor cell line exhibited statistically different median

157 The Notch-high cells sorted from solid-tumor cell lines exhibited characteristics of cancer ste

158 rc, both within the human tumors and in lung tumor cell lines exposed to hypoxia.

159 the HT29, HCT116, PC-3, HepG2, JR8, and M14 tumor cell lines expressing high levels of B7h, whereas

160 nt cell lines and selective cytotoxicity for tumor cell lines expressing mutant BRAF(V600E) versus th

161 Primary mouse embryo fibroblasts (MEFs) or tumor cell lines expressing SirT3 short-hairpin RNA exhi

162 In a panel of human tumor cell lines expressing various KRAS isoforms, we sh

163 These findings illustrate the variability of tumor cell line expression of versican, and demonstrate

164 However, tumor cell lines fail to engage in complete senescence u

165 ever, their utility is reduced by the use of tumor cell lines for implantation.

166 ) expression in 4 different human pancreatic tumor cell lines for the purpose of producing derivative

167 Validation experiments with human tumor cell lines, fresh human tumor xenografts in mice,

168 ker for AsiDNA treatment was validated in 43 tumor cell lines from various tissues and 15 models of c

169 eptor expression and Akt activation in human tumor cell lines, GBM stem cells, and primary tumor biop

170 in the weakly metastatic mouse 4TO7 mammary tumor cell line had no effect on proliferation or morpho

171 High metastatic human tumor cell lines had relatively high amounts of Id2 and

172 In this article, we show that the RENCA tumor cell line harbors TAMAs that can drive an antitumo

173 or their antiproliferative activity on three tumor cell lines (HeLa, A2780, and A2780cisR) and on a n

174 fective photodynamic activity on a number of tumor cell lines (HeLa, SK-MEL-28, A549, MCF-7) with eff

175 Herein, a normal cell line (NIH/3T3) and a tumor cell line (HepG2) were cultured on the 4-MBA modif

176 Cytotoxicity against 60 tumor cell lines, however, indicated that the (S)-isomer

177 TRR, NDOR1, and NOS2A expression in 23 human tumor cell lines; however, only POR protein was detectab

178 d anchorage-independent growth of a panel of tumor cell lines (IC(50) = 4.7 +/- 3 nM).

179 i) using gene essentiality data from several tumor cell lines, (ii) showing that these identified met

180 Silencing of aPKC in invasive breast-tumor cell lines impaired the delivery of MT1-MMP from l

181 cells showed enhanced cytotoxicity against a tumor cell line in vitro.

182 lines are the most frequently studied human tumor cell lines in cancer research.

183 CCT241533 blocked CHK2 activity in human tumor cell lines in response to DNA damage, as shown by

184 Investigations using multiple tumor cell lines in the orthotopic model suggested the i

185 The culture of tumor cell lines in three-dimensional scaffolds is consi

186 , LATS1 signaling was disrupted by 17-AAG in tumor cell lines in vitro and clinical ovarian cancers i

187 o inhibit cell growth of EGFR-overexpressing tumor cell lines in vitro and in a xenograft model in vi

188 nockdown of miR-155 attenuates the growth of tumor cell lines in vivo.

189 hibits the proliferation of a panel of human tumor cell lines including Colo205 (Rb(+)) and U937 (FLT

190 ino)prop-2-e n-1-one (10ae) was tested in 20 tumor cell lines including multidrug resistant phenotype

191 AMG 900 inhibited the proliferation of 26 tumor cell lines, including cell lines resistant to the

192 nificant cell death in a wide range of human tumor cell lines, including glioblastoma, astrocytoma, n

193 anoma line SK-MEL-2 (IC50 = 39 nM) and other tumor cell lines, including JeKo-1 (IC50 = 22 nM), HeLa

194 kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressi

195 oto-activation, VP may still inhibit certain tumor cell lines, including ovarian cancer, hepatocarcin

196 Moreover, overexpression of Egrs in tumor cell lines induced CEBPB and inhibited proliferati

197 Transduction of CX3CL1 and CX3CR1 in CRC tumor cell lines induced cell aggregation that strongly

198 low copy number of the ASncmtRNAs in several tumor cell lines induces cell death by apoptosis without

199 s study, we show that conditioned media from tumor cell lines induces expression of both CLIC4 and th

200 ration, whereas reexpression in a metastatic tumor cell line inhibited migration, proliferation, and

201 ro cytotoxic potency of SG2285 against human tumor cell lines is GI(50) 20 pmol/L.

202 We also show that translocase depletion in tumor cell lines leads to the accumulation of RAD51 on c

203 cutaneous xenografts, derived from the human tumor cell lines LNCaP (prostate), A549 (lung), and U251

204 ession of endogenous SMC genes in a prostate tumor cell line (LNCaP), none could induce the endogenou

205 display a range of activities against human tumor cell lines, malarial parasites, and bacterial path

206 ssociated lncRNAs were studied in two breast tumor cell lines, MCF-7 and MDA-MB-231.

207 intravasation sites), and a malignant breast tumor cell line, MDA-MB-231, embedded in type I collagen

208 Using two aggressive human tumor cell lines, MDA-MB-231 and MCF-7, we provide evide

209 In a wide array of tumor cell lines, mean inhibitory concentrations (IC(50)

210 (MEFs) expressing activated Ras(V12) and in tumor cell lines MIN6 and NG108-15.

211 Simvastatin inhibited the growth of most tumor cell lines more effectively than pravastatin in a

212 or their potency to induce cell death in two tumor cell lines, mouse breast cancer cell line EMT-6 an

213 ear signaling complexes (PSC) are present in tumor cell lines, mouse lung tumors, and mouse embryonic

214 FR-iRGD also exhibited antitumor activity in tumor cell lines, multicellular spheroids, and mice.

215 utilization of a novel human LNCaP prostate tumor cell line, N-AR, which stably expresses wild-type

216 ainst a panel of 60 well-characterized human tumor cell lines (NCI-60) to uncover combinations with g

217 in and mRNA levels were decreased in ovarian tumor cell lines not expressing the protein p53.

218 The cytotoxic activities on a panel of human tumor cell lines of these novel oxazaphosphorines, in bu

219 ensitive to anti-PlGF, but not in refractory tumor cell lines or in endothelial cells.

220 -204/211 is significantly lower in the NCI60 tumor cell line panel compared with that in 13 normal ti

221 The NCI-60 human tumor cell line panel is an invaluable resource for canc

222 liferative activity against the NCI-60 human tumor cell line panel revealed a correlation to clinical

223 tions when tested against the full NCI human tumor cell line panel.

224 ne mixtures were analyzed against four human tumor cell lines PC3 (prostate), DU145 (prostate), MDA-M

225 pharmacological inhibition of ERAP1 on human tumor cell lines perturbs their ability to engage severa

226 Mechanistic analyses revealed that each tumor cell line presented AH1, a common endogenous retro

227 ils showed cytotoxic effects on tested human tumor cell lines, related to the furanosesquiterpenoid c

228 Blocking miR-BART-18 function in an EBV(+) tumor cell line renders cells more susceptible to IFN-me

229 Here, we report that melanoma tumor cell lines require wild-type SOX10 expression for

230 Forced expression of ERG in prostate tumor cell lines resulted in significantly increased sec

231 V) could establish persistent infection in a tumor cell line, resulting in a steady antiviral state r

232 Further in vitro screen in 328 tumor cell lines revealed that tumor cells with KRAS, NR

233 nhibitory activity is seen in multiple human tumor cell lines, RI-1 holds promise as an oncologic dru

234 pmental Therapeutics Program (NCI-DTP) Human Tumor Cell Line Screen has screened hundreds of thousand

235 ad compound identified from the NCI-60 human tumor cell lines screen, NSC319726 (ZMC1), belongs to th

236 EGFR-1 signaling and biological responses in tumor cell lines sensitive to anti-PlGF, but not in refr

237 te with Pumilio to target E2F3, and multiple tumor cell lines shorten the 3' end of the E2F3 mRNA, re

238 Previous work using an epithelial tumor cell line showed that a Chlamydia-specific CD4 T c

239 nalysis of the gene expression signatures of tumor cell lines showed an inverse correlation between m

240 vitro inhibitory activity against ten human tumor cell lines showed that hydrolyzed rutin exerted a

241 Analysis of breast tumor cell lines showed that REST directly represses IRS

242 ative activity of the title compound on five tumor cell lines shows preference for the colon-rectal t

243 cytotoxic activity against a panel of human tumor cell lines similar to that of paclitaxel.

244 and moreover, revealed chemotherapeutic and tumor cell line specific activity patterns.

245 implanted with passaged, SHR-derived, breast tumor cell line, SST-2.

246 All tumor cell lines studied were equally susceptible to C7H

247 ionizing radiation promoted autophagy in all tumor cell lines studied, pharmacological inhibition of

248 Another gemcitabine-resistant tumor cell line, TC-1-GR, was developed in our laborator

249 ILT3.Fc inhibited the growth of CD166(+) tumor cell lines (TCL) derived from lymphoid malignancie

250 -hTf showed little cytotoxicity on all solid tumor cell lines tested but were very toxic to Ramos B-c

251 In most tumor cell lines tested, 8 exhibits efficient antiprolif

252 he parental virus following infection in two tumor cell lines tested, HT1080 and HeLa, and remained a

253 re taken from mice implanted with a melanoma tumor cell line that was transfected to express the fire

254 jected with three different syngenic mammary tumor cell lines that differ in their metastatic potenti

255 We identified ovarian tumor cell lines that retain UBB in a repressed state, u

256 an in vitro antitumor assay with seven human tumor cell lines, the bicyclic compounds inhibited selec

257 In some human tumor cell lines, the enhanced phosphorylation of Stat3

258 anslesion polymerase, Polzeta, can sensitize tumor cell lines to cisplatin, although the relevance of

259 Exposure of OV-susceptible tumor cell lines to conditioned media from RAW264.7 or p

260 spo(-/-)) mice, primary cells, and different tumor cell lines to examine the role of TSPO in erythrop

261 hibits the adhesion of polymorphonuclear and tumor cell lines to HUVECs; thus, we suggested that ICOS

262 atin or carboplatin increased the potency of tumor cell lines to induce IL-10-producing M2 macrophage

263 bition of PI3K signaling in a broad range of tumor cell lines to provide a strategy to overcome resis

264 GAT211 did not impede paclitaxel-induced tumor cell line toxicity.

265 , and the extent of delivery varied with the tumor cell line, tumor site, and host mouse strain used.

266 nd NAD(P)H oxidation levels increased in the tumor cell lines (uncoupling effect), resulting in a Del

267 en though mice were inoculated from the same tumor cell line under carefully controlled conditions.

268 and a low-passage cultured human pancreatic tumor cell line using clonogenic and DNA damage assays.

269 analyzed three pairs of testicular germ cell tumor cell lines using Affymetrix expression microarrays

270 nd quantify their usage in major cancers and tumor cell lines using direct RNA sequencing.

271 4 in the highly metastatic MDA-MB-231 breast tumor cell line was sufficient to restore E-cadherin exp

272 d messenger RNA (mRNA) expression in various tumor cell lines was downregulated upon treatment with p

273 factor [VEGF]) by MDSC-inducing human solid tumor cell lines was evaluated by RT-PCR.

274 compound with significant effects on several tumor cell lines was further modified to difluoro-dioxol

275 nt neurite outgrowth in Ewing sarcoma family tumor cell lines was mediated by Frizzled3, Dishevelled

276 tion, the in vitro proliferation of the lung tumor cell lines was not affected by either CD22 antibod

277 secting the underlying mechanism in prostate tumor cell lines we show the ERG-mediated up-regulation

278 Using an in vitro mouse thymus tumor cell line, we determined that H2(18)O provides sup

279 heterologous NIH 3T3 and human Ewing Family Tumor cell lines, we have demonstrated by quantitative p

280 nal Cancer Institute's NCI-60 panel of human tumor cell lines were correlated with permissivity for E

281 ctivities of compounds 2 and 3 over 60 human tumor cell lines were recorded.

282 All neural tumor cell lines were sensitive to nifurtimox, and IC50

283 rating 3- to 10-fold greater potency against tumor cell lines when compared with normal cells.

284 cell death (PCD) of CD38(+) multiple myeloma tumor cell lines when cross-linked in vitro by secondary

285 n the low nanomolar range against a panel of tumor cell lines, whereas cytotoxicity of the 4-N-alkylg

286 of anaphylatoxins, and CDC against distinct tumor cell lines, whereas no differences in ADCC by MNC

287 ing up to 6 orders less cytotoxic in the non-tumor cell line WI38, suggesting that key DNA sequences

288 levels of gamma-tubulin and RB1 and that in tumor cell lines with a nonfunctioning RB1, reduction of

289 Conversely, in human tumor cell lines with activating MAPK mutations, inhibit

290 rmal tissue, but is highly expressed in most tumor cell lines with an intact 9p21 locus.

291 nhibit selectively the growth of three human tumor cell lines with IC50 values in the low micromolar

292 elial cells to an isogenic series of mammary tumor cell lines with increasing metastatic potentials.

293 rther, we show lethality in invasive primary tumor cell lines with inhibiting H(+) efflux.

294 strated potent activity over a select set of tumor cell lines with particular selectivity toward mela

295 rated that treatment of a subset of BRAF(WT) tumor cell lines with RAF small molecule inhibitors resu

296 Accordingly, treatment of the colorectal tumor cell lines with the DNA methyltransferase inhibito

297 It is particularly effective against kidney tumor cell lines, with >250-fold higher anti-tumor activ

298 FT was expressed in the majority of 53 human tumor cell lines, with the highest levels in Caco-2 (col

299 r and inhibited the motility and invasion of tumor cell lines without any effect on their proliferati

300 Experiments with cultures of human tumor cell lines, xenografts of human tumors into immuno