ライフサイエンスコーパス: tumor grade

1 ed normal tissue and increased with specific tumor grade.

2 colorectal tumor tissues increased with the tumor grade.

3 ted with younger age at diagnosis and higher tumor grade.

4 ive tumors but was inversely correlated with tumor grade.

5 ith shorter disease-free survival and higher tumor grade.

6 , irrespective of hormone receptor status or tumor grade.

7 in tumor samples is correlated with advanced tumor grade.

8 ze, presence of lymphovascular invasion, and tumor grade.

9 ere elevated expression correlates with high tumor grade.

10 ma (37.6% of 117 cases) correlated with high tumor grade.

11 ed PEG3 mRNA expression that correlated with tumor grade.

12 ociation between loss of MEG3 expression and tumor grade.

13 and biological pathways that correlate with tumor grade.

14 x (GGI) is a 97-gene measure of histological tumor grade.

15 he TLR4 expression intensity correlated with tumor grade.

16 dicating a positive correlation with Gleason tumor grade.

17 tion in tumor tissues, which correlated with tumor grade.

18 their abundance is positively correlated to tumor grade.

19 f the uptake curve appeared to be related to tumor grade.

20 e its expression increases coordinately with tumor grade.

21 th high c-Myc expression and a more advanced tumor grade.

22 el, with the degree of loss correlating with tumor grade.

23 g from 10 to 41%, depending on TN status and tumor grade.

24 , number of positive lymph nodes, and higher tumor grade.

25 ted with relapse, local invasion and a worse tumor grade.

26 er biopsies and is associated with increased tumor grade.

27 mber of CD44+/alpha2beta1hi/CD133+ cells and tumor grade.

28 es of 54 gliomas of varying histogenesis and tumor grade.

29 ation between loss of BMP-RII expression and tumor grade.

30 s investigated after adjusting for stage and tumor grade.

31 t tumor angiogenesis varies depending on the tumor grade.

32 hed benign and cancer specimens of different tumor grade.

33 gnostic factor independent of tumor size and tumor grade.

34 n inverse correlation between cystatin C and tumor grade.

35 in cancer tissue correlated with increasing tumor grade.

36 ssues and a progressive loss with increasing tumor grade.

37 s also observed to increase as a function of tumor grade.

38 including distant metastasis, survival, and tumor grade.

39 -)) tumor subtypes, mammographic density and tumor grade.

40 ic tissue, stratifying patients according to tumor grade.

41 ression correlates with patient survival and tumor grade.

42 eptor type 2 (HER2 subtype), tumor size, and tumor grade.

43 ns and suggested a positive correlation with tumor grade.

44 types, increased patient survival, and lower tumor grade.

45 meters showed a significant correlation with tumor grade.

46 uction was significantly correlated with the tumor grade.

47 are increased and positively correlate with tumor grade.

48 oma , and it provides insights regarding the tumor grade.

49 s inversely with survival and increases with tumor grade.

50 bolism may be related to an association with tumor grade.

51 s, CYP27A1 expression levels correlated with tumor grade.

52 presses tumor cell proliferation and reduces tumor grade.

53 , 1.10; 95% CI, 1.01 to 1.20; P = .026), and tumor grade.

54 after age correction and were compared among tumor grades.

55 ation and tumor formation, although at lower tumor grades.

56 rade 3 breast tumors, as compared with lower tumor grades.

57 y the elective nature of surgery and earlier tumor grades.

58 mon, differential expression pattern between tumor grades.

59 vels and elevated ANXA2 levels in increasing tumor grades.

60 of MLK3 was inversely correlated with HER2+ tumor grades.

61 de useful information for preoperative glial tumor grading.

62 ry to perfusion MR technique in preoperative tumor grading.

63 Results Low-grade tumors (grade 0, 1, or 2) demonstrated a favorable long-

64 Subgroups were formed based on tumor grade (1 vs. 3), adjuvant chemotherapy (use vs. no

65 azard ratio, 1.22 [95% CI, 1.07-1.40]), high tumor grade (1.34 [1.16-1.55]), mucinous histological ty

66 allowed full recapitulation of the original tumor (grade 2/grade 3 serous adenocarcinoma), whereas >

67 or <1.5 mm, pT stage, pN stage, LNR >/=0.2, tumor grade 3, and lymphovascular invasion were signific

68 gression [DP], 13%) versus 33% of high-grade tumors (grade 3 or 4) (complete response, 0%; partial re

69 whether prostate weight was associated with tumor grade, advanced disease, or risk of biochemical pr

70 Data collected include stage of disease, tumor grade, age at diagnosis, and menopausal status.

71 at an academic/research program, and higher tumor grade all predicted neoadjuvant RT administration.

72 ection, n = 8), prior chemotherapy (n = 16), tumor grade (anaplastic, n = 35), and tumor location (in

73 carcinomas was strongly associated with high tumor grade and advanced disease stage.

74 ript and protein correlate with increases in tumor grade and alterations in subcellular localization

75 psin B transcript and protein with increased tumor grade and changes in subcellular localization and

76 cteristics (serum prostate-specific antigen, tumor grade and clinical stage) and by treatment type (r

77 ent samples, with expression increasing with tumor grade and correlating with shorter survival times

78 or progression by relating its expression to tumor grade and demonstrating its role in the regulation

79 When clinical covariates, tumor grade and estrogen receptor H-score, were included

80 n of information on breast cancer pathology (tumor grade and estrogen receptor/progesterone receptor

81 Silibinin-fed groups had a lower tumor grade and higher incidence of prostatic intraepith

82 arcinomas strongly correlates with increased tumor grade and is associated with methylation of the HO

83 P-2 expression is positively correlated with tumor grade and is highest in metastatic tumors.

84 hat PDGFR signaling quantitatively regulates tumor grade and is required to sustain high-grade oligod

85 We thus evaluated the role of tumor grade and its association with VTE.

86 The tumor grade and Ki-67 proliferation index were obtained

87 D68(+) macrophages positively correlate with tumor grade and liver metastasis in human pancreatic neu

88 sitively correlated with cell proliferation, tumor grade and malignancy.

89 Prognosis is clearly related to tumor grade and margin status.

90 binding homeobox 1 (ZEB1) is associated with tumor grade and metastasis in lung cancer, likely due to

91 reted HAase and the secretion increased with tumor grade and metastasis.

92 HYAL1 staining in tumor cells increased with tumor grade and metastasis.

93 rtional hazards model only in the absence of tumor grade and nodal status.

94 ociations of metabolism with patient age and tumor grade and of blood flow with estrogen receptor sta

95 tly associated with histopathological stage, tumor grade and overall patient survival in bladder tumo

96 Tumor grade and patient age are important prognostic fac

97 tagenes also have predictive value regarding tumor grade and patient outcomes.

98 echanism, as well as characteristics such as tumor grade and patient survival.

99 al imaging, residual tumor in explant >2 cm, tumor grade and perineural invasion in explant.

100 er, their direct correlation with increasing tumor grade and poor prognosis has posed a long-standing

101 association of VGF expression with advanced tumor grade and poor survival in patients with lung aden

102 the high level of Mcl-1 was related to high tumor grade and poor survival of breast cancer patients.

103 h glioma, serum YKL-40 levels correlate with tumor grade and potentially tumor burden in GBM.

104 ere its expression inversely correlates with tumor grade and predicts prognosis.

105 variety of human tumors and correlates with tumor grade and prognosis.

106 ith the coexpression of MTA1 as well as with tumor grade and proliferation of primary breast tumor sa

107 associated with increased proliferation and tumor grade and reduced metastasis-free patient survival

108 n oncology, where it could be used to assess tumor grade and response to treatment.

109 nd to correlate CT perfusion parameters with tumor grade and serum markers.

110 t cancer tissues and is associated with high tumor grade and shorter patient survival time.

111 At present, tumor grade and size are the primary clinicopathological

112 dependent prognostic indicator regardless of tumor grade and size, estrogen or progesterone receptor

113 creased BTG2 expression correlates with high tumor grade and size, p53 status, blood and lymph vessel

114 The analysis was stratified by tumor grade and stage and by age and comorbidity at diag

115 kb1 expression was inversely correlated with tumor grade and stage, arguing that Lkb1 inactivation or

116 lated with more advanced tumor stage, higher tumor grade and the presence of distant metastasis in Pa

117 nces in ADCs, skewness, and kurtosis between tumor grade and the presence of lymphovascular invasion.

118 tified before surgery using a score based on tumor grade and the severity of underlying liver disease

119 including age, human papillomavirus status, tumor grade and TP53 mutation, and N classification.

120 Nuclear 4ICD inversely correlated with tumor grade and tumor mitosis.

121 n, increased proliferative indices, advanced tumor grade and undifferentiated histology.

122 carce information on the association between tumor grade and VTE is available.

123 (18)F-FDOPA uptake in brain tumors predicted tumor grade and was associated with tumor proliferative

124 consistently overexpressed than 67LR in all tumor grades and stages.

125 A PET might serve as a noninvasive marker of tumor grading and might provide a useful surrogate of tu

126 tween enhanced NPM1 expression and increased tumor grading and poor prognosis, whereas in contrast, A

127 other clinicopathological features (age and tumor grade) and other molecular alterations commonly fo

128 stability attractor strongly associated with tumor grade, and a lymphocyte-specific attractor.

129 r size, positive lymph nodes, margin status, tumor grade, and age), the relative hazard for patients

130 ficantly associated with pathological stage, tumor grade, and altered retinoblastoma (RB) expression.

131 s by helping distinguish tumor types, assess tumor grade, and attempt to determine tumor margins.

132 ted with specific cancer subtypes, increased tumor grade, and decreased overall survival.

133 associated with increased burden, increased tumor grade, and elevated serum chromogranin A (CgA).

134 or interleukin-6 (IL-6) levels increase with tumor grade, and elevated serum IL-6 correlates with poo

135 y was reviewed to determine histologic type, tumor grade, and estrogen receptor, progesterone recepto

136 the number of positive lymph nodes, T stage, tumor grade, and ex vivo proximal margin length >3.8 cm

137 is reduced in primary PCas as a function of tumor grade, and inversely correlates with the prolifera

138 true in soft tissue sarcomas, it can predict tumor grade, and it is of value in staging, restaging an

139 sitivity, estrogen receptor negativity, high tumor grade, and large tumor size.

140 endent variable, older age, T2 disease, high tumor grade, and local recurrence were associated with r

141 er age at diagnosis, white race, unfavorable tumor grade, and low comorbidity were each associated wi

142 and E-cadherin, Snail, metastatic potential, tumor grade, and lymph-vascular invasion during breast c

143 rmal growth factor receptor 2 (HER2) status, tumor grade, and lymphovascular invasion are relevant; O

144 omponents (fibrous, chondroid, and osteoid), tumor grade, and marrow involvement.

145 Younger age at diagnosis, poorer tumor grade, and negative estrogen receptors (ERs) were

146 ons of tumor diameter and nodal status (TN), tumor grade, and other factors with patients' outcomes d

147 lates strongly with chemotherapy resistance, tumor grade, and overall survival.

148 s integrating tumor-node-metastasis staging, tumor grade, and performance status were compiled for de

149 with increased cytogenetic complexity, high tumor grade, and poor prognosis.

150 50 years, female sex, being married, higher tumor grade, and presence of colon tumors.

151 ypoxia gene expression signature, increasing tumor grade, and reduced patient survival.

152 nts were associated with pathological stage, tumor grade, and survival when validated by immunohistoc

153 Prognosis was dependent on tumor grade, and the presence of bone metastasis was ass

154 ntially methylated loci (DML) increased with tumor grade, and the vast majority were due to hypomethy

155 , tumor diameter, lymphatic vessel invasion, tumor grading, and Lauren classification, the PRSC was t

156 1; 95% CI, 1.31 to 1.69) and those with high tumor grade (AOR, 30.76; 95% CI, 26.48 to 35.73) had sig

157 In contrast to tumor stage, different tumor grades are associated with distinct gene expressio

158 tients with HCC for transplantation based on tumor grade as determined by preoperative NCB.

159 age, Lauren histotype, lymph-node ratio, and tumor grade as independent prognostic factors in gastric

160 he first course of therapy, patient age, and tumor grade as significant independent prognostic covari

161 Given the TN status, the factors of tumor grade (available in 43,590 patients) and Ki-67 sta

162 omas of the prostate can be categorized into tumor grades based on the extent to which the cancers hi

163 Because of this tumor grade-based differential growth, the E1-deleted ad

164 sults included tumor type, malignancy, final tumor grade, biopsy complications, and effect on eventua

165 The effect of age and tumor grade, both individually and together, on BOLD fun

166 Overexpression of p53 was associated with tumor grade but not with patient outcome.

167 d hyperpolarized alanine also increased with tumor grade but showed more overlap between the groups.

168 (18)F-FDG PET may be helpful in tumor grading but offers inadequate discrimination betwe

169 LAMC2 expression levels were associated with tumor grade, but inversely with nodal status.

170 s in combination with PR and HER2 status and tumor grade by using the threshold of more than 30 as a

171 Of these, tumor size, tumor grade, cathepsin-D, Ki-67, S-phase fraction, mitot

172 with extended follow-up periods, tumor size, tumor grade, cathepsin-D, Ki-67, S-phase fraction, mitot

173 tyrosine kinase is associated with increased tumor grade, chemotherapy resistance, and decreased pati

174 , Eastern Cooperative Oncology Group status, tumor grade, chemotherapy, and radiation regimen and day

175 of survival after adjusting for patient age, tumor grade, clinical tumor stage, lymphovascular invasi

176 lates with better patient survival and lower tumor grade consistent with its tumor suppressor activit

177 Stage and tumor grade continue to appear to be valid prognostic in

178 1 primary breast cancers, we found that high tumor grade correlated significantly with elevated cytop

179 is significantly associated with increasing tumor grade, decreased levels of apoptosis, and with adv

180 Tumor grade did not influence the levels of expression o

181 whereas unaligned cell lines using original tumor grades did not.

182 xpression was positively correlated with low tumor grade, diploidy, and low S-phase fraction, all bio

183 n was independent of patient age at surgery, tumor grade, disease stage, and IGF-II or IGFBP-3 expres

184 d that protein overexpression was related to tumor grade, disease stage, Ki-67 expression, and a shor

185 Advanced age and tumor grade do not have a combined effect for reduction

186 r age, tumor size, number of positive nodes, tumor grade, estrogen receptor status, and human epiderm

187 age younger than 50 years at diagnosis, high tumor grade, estrogen receptor-negative status, progeste

188 enting clinicopathological features, such as tumor grade, expression status of estrogen receptor and

189 status, pathologic tumor size, node status, tumor grade, facility type and location, and volume of b

190 found between tumor iodine concentration and tumor grade for both clear cell (tau = 0.85; P < .001) a

191 f PSCA expression correlated with increasing tumor grade for both STCCs and ITCCs (P < 0.001).

192 y with several parameters of poor prognosis (tumor grade, growth pattern, muscle invasion, tumor stag

193 d with several parameters of poor prognosis (tumor grade, growth pattern, muscle invasion, tumor stag

194 Consideration of hormone receptor status and tumor grade had little effect on the ethnic patterns.

195 The validity of NCB to predict final tumor grade has not been previously assessed.

196 Tumor grade helps determine which tracer should be selec

197 Tumor grade (high vs low) was compared with ultrahigh-fi

198 ecrease in nuclear Smad 3 abundance and high tumor grade, high architectural grade, larger tumor size

199 Poor tumor grading, high American Joint Commission on Cancer

200 tion, such as World Health Organization 2007 tumor grade, histology, and isocitrate dehydrogenase 1 R

201 1-associated breast cancer in regard to high tumor grade, hormone receptor negativity, a high inciden

202 unfavorable prognostic features such as high tumor grade, hormone receptor negativity, and high proli

203 correlation between metabolomic profile and tumor grade/hormone receptor status was found.

204 ired eGFR (HR = 3.32, 95% CI: 1.70-6.48) and tumor grade (HR = 1.94, 95% CI: 1.36-2.77) were independ

205 T-2 expression was inversely correlated with tumor grade, implicating its potential role in glial tum

206 ATP11B expression was correlated with higher tumor grade in human ovarian cancer samples and with cis

207 G6PC expression also correlated with tumor grade in human primary HCCs.

208 RAP1 expression is inversely correlated with tumor grade in several cancers, these data suggest that,

209 clinical American Joint Committee on Cancer tumor grade in the IFNalpha2b group.

210 tro and significantly increases according to tumor grade in vivo (P < 0.01), with highest levels in g

211 EF5 binding increased as the tumor grade increased and was significantly associated w

212 xpression of PSMA is upregulated as prostate tumor grade increases and is found in the vasculature of

213 As tumor grade increases, we find enhanced proliferation of

214 sion in 90 ccRCC patient specimens for which tumor grade information was available.

215 s to define a new cohort of patients in whom tumor grade is a very important prognostic variable.

216 more, a subset of genes associated with high tumor grade is quantitatively correlated with the transi

217 High tumor grade is the most consistent factor associated wit

218 elates with poor patient survival and higher tumor grade, is consistent with its oncogenic activity.

219 ends on age, World Health Organization (WHO) tumor grade, Karnofsky performance score, cytological ty

220 After excluding patients with advanced tumor grades, laparoscopic surgery was still associated

221 riate analysis was performed controlling for tumor grade, location, surgery type, functional hormonal

222 nt with surgery or radiation therapy, higher tumor grades, lower neighborhood socioeconomic status, a

223 specific survival by age, sex, surgery type, tumor grade, lymph node status, and use of radiation the

224 volume and ADC can be used for prediction of tumor grade, lymphovascular invasion, and depth of myome

225 T and N stage, histologic type, tumor size, tumor grade, lymphovascular invasion, perineural invasio

226 candidates for transplantation based on NCB tumor grade may be misleading, as NCB tumor grade often

227 The tumor grade may help identify patients with cancer who a

228 that the expression of ARRDC3 decreases with tumor grade, metastases and recurrences.

229 PS) correlated strongly with histopathologic tumor grade, MVD, and K(PS) values derived by using albu

230 y with cytoplasmic p-CDK2 (P < 0.0001), high tumor grade, negative estrogen/progesterone receptor sta

231 pressing Skp2 are also characterized by high tumor grade, negativity for Her-2, basal-like phenotype,

232 s (rN) (odds ratio [OR], 5.58; P < .001) and tumor grade (NET-G2 vs NET-G1: OR, 4.87; P < .001) (firs

233 r recurrence after adjusting for tumor size, tumor grade, nodal disease, estrogen receptor status, pr

234 nd was associated with larger tumors, higher tumor grades, node metastasis and shorter patient surviv

235 5% CI, 0.67 to 0.68) for the model including tumor grade, number of collected metastatic lymph nodes,

236 Of note, higher tumor grade of human ccRCC was correlated with a concomi

237 on NCB tumor grade may be misleading, as NCB tumor grade often did not correlate with grade or presen

238 uld correlate with the presence of tumor and tumor grade or burden.

239 creased (18)F-FDG uptake and a more advanced tumor grade or growth in breast cancer.

240 rmine whether there was any correlation with tumor grade or histological type.

241 uffer from cognitive deficits, regardless of tumor grade or location.

242 on only with aneuploidy; no association with tumor grade or S-phase fraction was seen for ERbeta.

243 kg/m(2) (obesity; OR = 2.01; P = .014), high tumor grade (OR = 0.40; P = .018), KRAS mutation (OR = 0

244 reduction with respect to age, nodal status, tumor grade, or progesterone receptor status and no indi

245 There was some evidence of heterogeneity by tumor grade ( P = .02), with an increased risk for low-i

246 the eastern United States (P = .02), and low tumor grade (P < .0001) were associated with ovarian pre

247 umor-associated Cyr61 protein correlate with tumor grade (P < 0.001) and with c-Met protein expressio

248 orrelates with Gleason score (P < 0.001) and tumor grade (P < 0.001).

249 imbalance on chromosome 11 in the stroma and tumor grade (P = .0013), on chromosomes 1, 2, 5, 18, 20,

250 Histopathologic features of PD were high tumor grade (P = .005), high Ki-67 score (P = .002), and

251 or 1alpha (P < 0.05), tumor size (P = 0.03), tumor grade (P = 0.0001), and Chalkley vessel count (P =

252 xpression was inversely associated with high tumor grade (P = 0.0017) and obesity (body mass index >

253 association between primary tumor SUVmax and tumor grade (P = 0.30).

254 es for this factor were associated with high tumor grade (P heterogeneity = 0.02), younger age at men

255 EFS was not associated with tumor grade (P= 0.98), histologic subtype (P= 0.17), or

256 e, hormone receptor status, HER2-neu status, tumor grade, pathologic tumor size, lymphatic invasion,

257 deration of Gynecology and Obstetrics stage, tumor grade, pelvic node status, and treatment with conc

258 Rather, in patients with grade IV gliomas, tumor grade played a dominant role in reduction of SI ch

259 antly associated with high tumor stage, high tumor grade, positive lymph nodes and presence of distan

260 dvanced T stage, lymph node metastasis, high tumor grade, positive resection margin, perineural, and

261 Histologic tumor grade predicted survival.

262 Whereas final pathologic tumor grade predicted the presence of microscopic vascul

263 here was a marked difference with respect to tumor grade, prevalence of necrosis, initial presentatio

264 rams, and BAP1 loss was associated with high tumor grade (q = 0.0005).

265 NA expression does not appear to be prostate tumor grade related and is restricted exclusively to pro

266 rrelated negatively and positively with lung tumor grade, respectively.

267 miRNA expression by RT-qPCR correlated with tumor grade, size, and presence of carcinoma in situ for

268 e Cox's regression analysis, age, sex, race, tumor grade, stage at diagnosis, lymph/vascular invasion

269 redictors of tumor recurrence independent of tumor grade, stage, and preoperative prostate-specific a

270 ther significant factors included age, race, tumor grade, stage, location, and N stage.

271 Its applications include tumor grading, staging, therapeutic monitoring, and prog

272 gative group with respect to age, sex, race, tumor grade, subsites and stage, or EGFR expression by a

273 he associations between clinical phenotypes (tumor grade, survival) and cell phenotypes, such as shap

274 dels were adjusted for covariates (age, sex, tumor grade, T/N stage, tumor location, Eastern Cooperat

275 ith smaller diameter tumors and with a lower tumor grade than women from seven other ethnic groups.

276 score, fibrosis score, and Edmondson-Steiner tumor grade) that can be determined before surgery were

277 5% CI, 1.31-2.47), regardless of tumor size, tumor grade, tumor histology or radiation history.

278 tivariable Cox regression analysis including tumor grade, tumor histology, tumor sites, stage, sex, a

279 ry of BC) and prognostic factors (TNM stage, tumor grade, tumor size, age at diagnosis, estrogen rece

280 g for major clinical characteristics such as tumor grade, tumor size, anatomic site, and patient age.

281 endent prognostic factors were nodal status, tumor grade, tumor size, and estrogen-receptor status (P

282 st for year of diagnosis, age, race, gender, tumor grade, tumor size, TNM stage, and percent of nodes

283 indicate potential for noninvasive prostate tumor grading using quantitative (111)In-capromab pendet

284 more likely to present increased pathologic tumor grade, vascular endothelial growth factor expressi

285 es of prostate tumor significantly decreased tumor grade via antiproliferative effect, and inhibition

286 World Health Organization classification tumor grade was associated with number (P<.0005) and siz

287 When the tumor grade was excluded, rN (OR, 4.73; P = .001) and ra

288 ation between tumor iodine concentration and tumor grade was investigated.

289 t of NCB and surgical pathology to determine tumor grade was poor (kappa = 0.18, P < 0.0001).

290 Primary tumor grade was the only prognostic variable significant

291 In contrast, when tumor grading was based on the final surgical specimen,

292 6), patient age (50-60 years: 3.4; 1.8-6.7), tumor grade (well differentiated: 2.2; 1.5-3.0), surgica

293 2 to 1.51; P = .65); age, margin status, and tumor grade were associated with LR-free survival (all P

294 chromosome 11 in the stroma associated with tumor grade were D11S1999 (P = .00055) and D11S1986 (P =

295 growth factor receptor 2 (HER2) status, and tumor grade were then individually correlated with ODRS.

296 RASSF1A methylation increased with tumor grade, while BLU methylation was seen at similar f

297 t cancer biopsies correlated positively with tumor grade, while specimens from patients with benign h

298 The association of tumor grade with recently identified biomarkers indicate

299 re associated with larger tumor size, higher tumor grade with resultant shortened tumor-free survival

300 uman prostate tumor tissues as a function of tumor grade with the highest expression level in metasta