ライフサイエンスコーパス: tumor necrosis factor-alpha converting enzyme

1 nfected cells in a soluble truncated form by tumor necrosis factor alpha-converting enzyme.

2 drolyzed peptide substrates of matrixins and tumor necrosis factor-alpha converting enzyme.

3 of oxygen radicals, which in turn stimulate tumor necrosis factor alpha-converting enzyme (a disinte

4 on (knockout), we now demonstrate that TACE (tumor necrosis factor alpha converting enzyme), a member

5 ecretase activity and enhanced hydrolysis of tumor necrosis factor alpha-converting enzyme, a primary

6 from the surface of activated leukocytes by tumor necrosis factor-alpha converting enzyme, a cell su

7 Inhibition of tumor necrosis factor-alpha-converting enzyme abrogated

8 odulin protein expressions, inhibited tissue tumor necrosis factor-alpha converting enzyme activity,

9 Changes in basal tumor necrosis factor-alpha-converting enzyme activity a

10 Similar changes in monocyte tumor necrosis factor-alpha-converting enzyme activity c

11 s had substantially elevated levels of basal tumor necrosis factor-alpha-converting enzyme activity t

12 GHR metalloproteolysis can be catalyzed by tumor necrosis factor-alpha-converting enzyme (ADAM-17)

13 DC lacking MT1-MMP, and instead requires the tumor necrosis factor alpha-converting enzyme ADAM17 (a

14 This effect is mediated by activation of tumor necrosis factor alpha-converting enzyme (ADAM17),

15 al H19-7/IGF-IR neuronal cells and inhibited tumor necrosis factor-alpha-converting enzyme alpha-secr

16 The membrane-bound proteases tumor necrosis factor alpha-converting enzyme and furin

17 as ERBB4) undergoes sequential processing by tumor necrosis factor-alpha converting enzyme and presen

18 o be mediated by reduced cleavage of GPIb by tumor necrosis factor-alpha-converting enzyme and reduce

19 flammatory response syndrome, monocyte basal tumor necrosis factor-alpha-converting enzyme, and its i

20 y reduced, due to inhibition of the sheddase-tumor necrosis factor-alpha-converting enzyme by Abeta.

21 Monocyte tumor necrosis factor-alpha-converting enzyme catalytic

22 ptide, sol-tumor necrosis factor production, tumor necrosis factor-alpha-converting enzyme expression

23 Activation of protein kinase C and tumor necrosis factor-alpha-converting enzyme family met

24 idues 646-657 was incubated with recombinant tumor necrosis factor-alpha-converting enzyme, fragments

25 A better understanding of how tumor necrosis factor-alpha-converting enzyme function i

26 rocollagen type 1 alpha2 gene and the ADAM17/tumor necrosis factor-alpha converting enzyme gene.

27 increased expression of ADAM 10 and ADAM 17 (tumor necrosis factor-alpha-converting enzyme) in antral

28 contrast, the matrix metalloproteinase/TACE (tumor necrosis factor-alpha-converting enzyme) inhibitor

29 and PMA and was specifically inhibited by a tumor necrosis factor alpha-converting enzyme metallopro

30 cies, increased expression of pro-HB-EGF and tumor necrosis factor alpha-converting enzyme (pro-HB-EG

31 ealth Evaluation II score and the attenuated tumor necrosis factor-alpha-converting enzyme response t

32 Catalytic efficiency with the pro-tumor necrosis factor-alpha converting enzyme substrate

33 ch higher efficiency the hydrolysis of a pro-tumor necrosis factor-alpha converting enzyme synthetic

34 Because the metalloproteinase tumor necrosis factor alpha converting enzyme (TACE) rel

35 ning transmembrane protein but is cleaved by tumor necrosis factor alpha converting enzyme (TACE) to

36 etalloproteinase-3, TIMP-3, that can inhibit tumor necrosis factor alpha converting enzyme (TACE), bu

37 Tumor necrosis factor alpha-converting enzyme (TACE) is

38 Tumor necrosis factor alpha-converting enzyme (TACE) is

39 tion of the extracellular region of ADAM-17 (tumor necrosis factor alpha-converting enzyme (TACE)) by

40 Previously, we established that tumor necrosis factor alpha-converting enzyme (TACE/ADAM

41 In parallel, the proteolytic activity of tumor necrosis factor alpha-converting enzyme (TACE; ADA

42 In the present work, we report that tumor necrosis factor alpha-converting enzyme (TACE; ADA

43 Tumor necrosis factor-alpha converting enzyme (TACE or A

44 d from chimeric mice, which express inactive tumor necrosis factor-alpha converting enzyme (TACE(Delt

45 The addition of an inhibitor of tumor necrosis factor-alpha converting enzyme (TACE) blo

46 Tumor necrosis factor-alpha converting enzyme (TACE) is

47 Tumor necrosis factor-alpha converting enzyme (TACE) is

48 secretion) of tumor necrosis factor (TNF) by tumor necrosis factor-alpha converting enzyme (TACE) may

49 Tumor necrosis factor-alpha converting enzyme (TACE) was

50 ctivation gene 3 (LAG-3) and metalloprotease tumor necrosis factor-alpha converting enzyme (TACE) wor

51 Tumor necrosis factor-alpha converting enzyme (TACE), a

52 Our study identifies ADAM17, also called tumor necrosis factor-alpha converting enzyme (TACE), as

53 The responsible protease, tumor necrosis factor-alpha converting enzyme (TACE), ha

54 PR), undergoes regulated cleavage by the MMP tumor necrosis factor-alpha converting enzyme (TACE).

55 as observed in newborn mice lacking EGFR and tumor necrosis factor-alpha converting enzyme (TACE).

56 racterization of a fluorogenic substrate for tumor necrosis factor-alpha converting enzyme (TACE).

57 disintegrin and metalloprotease) identified tumor necrosis factor-alpha converting enzyme (TACE)/ADA

58 ese hamster ovary cells that lack functional tumor necrosis factor-alpha converting enzyme (TACE, als

59 We recently demonstrated that tumor necrosis factor-alpha converting enzyme (TACE/ADAM

60 We previously implicated tumor necrosis factor-alpha converting enzyme (TACE/ADAM

61 and genetic reconstitution studies identify tumor necrosis factor-alpha converting enzyme (TACE/ADAM

62 The responsible protease, tumor necrosis factor-alpha converting enzyme (TACE/ADAM

63 sed from cells, a process termed "shedding." Tumor necrosis factor-alpha converting enzyme (TACE/ADAM

64 -myristate 13-acetate (PMA), and we identify tumor necrosis factor-alpha converting enzyme (TACE; ADA

65 the cell surface death receptors mediated by tumor necrosis factor-alpha converting enzymes (TACE/ADA

66 Like tumor necrosis factor-alpha-converting enzyme (TACE or A

67 from genetically deficient mice, we identify tumor necrosis factor-alpha-converting enzyme (TACE or A

68 owth factor)-like growth factor (HB-EGF) and tumor necrosis factor-alpha-converting enzyme (TACE) (AD

69 d is required for Notch processing by ADAM17/tumor necrosis factor-alpha-converting enzyme (TACE) and

70 cleaved in cells lacking the metalloprotease tumor necrosis factor-alpha-converting enzyme (TACE) and

71 Recently, tumor necrosis factor-alpha-converting enzyme (TACE) has

72 , Src small interfering RNA (siRNA), and the tumor necrosis factor-alpha-converting enzyme (TACE) inh

73 FR phosphorylation inhibitor AG1478, and the tumor necrosis factor-alpha-converting enzyme (TACE) inh

74 The introduction of enzymatically active tumor necrosis factor-alpha-converting enzyme (TACE) int

75 Tumor necrosis factor-alpha-converting enzyme (TACE) is

76 Tumor necrosis factor-alpha-converting enzyme (TACE) is

77 Here we report that tumor necrosis factor-alpha-converting enzyme (TACE) is

78 The tumor necrosis factor-alpha-converting enzyme (TACE) is

79 diverse group of membrane ectoproteins, and tumor necrosis factor-alpha-converting enzyme (TACE), a

80 e form by proteolytic cleavage that involves tumor necrosis factor-alpha-converting enzyme (TACE), an

81 uction, leading to EPCR shedding mediated by tumor necrosis factor-alpha-converting enzyme (TACE), en

82 upport of this hypothesis, BDNF up-regulated tumor necrosis factor-alpha-converting enzyme (TACE)/ADA

83 Tumor necrosis factor-alpha-converting enzyme (TACE, or

84 a mechanism involving the phosphorylation of tumor necrosis factor-alpha-converting enzyme (TACE/ADAM

85 malian N-TIMP-3 in strongly inhibiting human tumor necrosis factor-alpha-converting enzyme (TACE/ADAM

86 s was impaired by inhibition or depletion of tumor necrosis factor alpha-converting enzyme, the enzym

87 Inhibition of tumor necrosis factor-alpha-converting enzyme using TNF-