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1 tate of a GR-induced promoter (mouse mammary tumor virus).
2 oses additional oncogenic properties of this tumor virus.
3 oma-associated herpesvirus (KSHV) is a human tumor virus.
4 ions by viruses like HIV-1 and mouse mammary tumor virus.
5 uppressor pathway in a manner similar to DNA tumor viruses.
6 so targeted by oncoproteins expressed by DNA tumor viruses.
7 frequent integration sites for mouse mammary tumor viruses.
8 ar stomatitis, pseudocowpox, and Yaba monkey tumor viruses.
9 cts associated with infections with many DNA tumor viruses.
10 mechanisms of transformation employed by DNA tumor viruses.
11 lomaviruses are a family of nonenveloped DNA tumor viruses.
12 through the use of GEM models for human DNA tumor viruses.
13 s, human papillomaviruses, and mouse mammary tumor viruses.
14 red to mediate transformation induced by DNA tumor viruses.
15 in many cancers and is also targeted by DNA tumor viruses.
16 milar to that of T antigens of the small DNA tumor viruses.
18 genous superantigen encoded by mouse mammary tumor virus 8 (Mtv-8) by either deletion or T-cell recep
19 radioimmunoconstruct in a transgenic Nestin-tumor virus A (Ntva) mouse model of high-grade glioblast
20 he Keratin 6a (K6a) gene promoter to express tumor virus A (tva), which encodes the receptor for avia
21 ection with EnvA-pseudotyped rabies virus in tumor virus A receptor transgenic mice, indicating that
22 s for two of these viruses-the mouse mammary tumor virus (a retrovirus) and Machupo virus (an arenavi
24 ct with the transforming oncoproteins of DNA tumor viruses and this led to rapid advances in our unde
25 s are attractive metabolic targets to combat tumors, virus and parasitic diseases but have not yet be
27 ffective in malignant diseases for which DNA tumor viruses are etiologic agents and that antitumor ac
28 ental effect on viral replication.IMPORTANCE Tumor viruses are known to interact with machinery respo
33 key target of oncoproteins expressed by DNA tumor viruses, but RNA viruses are not known to regulate
34 erse transcriptase in retroviruses (then RNA tumor viruses) by David Baltimore and Howard Temin revol
35 ion and survival in transgenic mouse mammary tumor virus-c-Myc mouse mammary carcinoma cells are both
36 initiated by an overexpressed mouse mammary tumor virus-c-myc transgene, which on its own produced p
38 Human papillomaviruses (HPV) are small DNA tumor viruses causally associated with cervical cancer.
40 y, mammary tumors derived from mouse mammary tumor virus-CR-1 mice showed a dramatic reduction of Cav
41 isolated from Cav-1 null(-/-)/mouse mammary tumor virus-CR-1 transgenic animals showed enhanced moti
42 I (TGFbetaRI), either by using mouse mammary tumor virus-Cre mice or by delivering adenoviral vector
44 vivo, we created and analyzed murine mammary tumor virus-Cre-mediated FIP200 conditional knock-out (C
46 appears to interact with naked mouse mammary tumor virus DNA somewhat differently than with chromatin
48 adenomas with lung metastases [mouse mammary tumor virus-driven polyoma virus middle T oncogene (MMTV
49 d 1970s for the discovery of the first human tumor viruses--EBV, hepatitis B virus, and the papilloma
51 antigen, under control of the mouse mammary tumor virus enhancer/promoter, was used to produce mamma
53 e sheep retrovirus (JSRV) and enzootic nasal tumor virus (ENTV) induce epithelial tumors in the airwa
55 e sheep retrovirus (JSRV) and enzootic nasal tumor virus (ENTV), is responsible for their distinct lo
56 ession of latency protein LMP2A by the human tumor virus Epstein-Barr virus (EBV) activates phosphati
57 t virus infection, specifically by the human tumor virus Epstein-Barr virus (EBV) induces a spectrum
58 to harbor exogenous agents such as the human tumor viruses Epstein-Barr virus (EBV) and human papillo
61 rus-ErbB2 Ink4a/Arf(+/-) mice, mouse mammary tumor virus-ErbB2 Ink4a/Arf(wt) mammary tumors showed in
64 oma-associated herpesvirus (KSHV) is a human tumor virus expressing latent antigens critical for path
65 ge of 4 months, 100% of female mouse mammary tumor virus-EZH2 virgin mice developed intraductal epith
66 and their application to the study of mouse tumor viruses facilitated the assembly of the first gene
70 nt to the entire 3'-end of the mouse mammary tumor virus genome, but further deletions at the 5'- or
74 Human papillomavirus type 16 (HPV-16), a DNA tumor virus, has a causal role in cervical cancer, and t
80 ly analyze protein profiles in mouse mammary tumor virus/HER2 transgenic mouse frozen tumor sections
82 This provirus, designated as human mammary tumor virus (HMTV), was 95% homologous to MMTV and revea
83 s for the identification of additional human tumor viruses--human T-cell leukemia virus type 1, hepat
86 Here, we identify the oncogenes of the DNA tumor viruses, including E7 from human papillomavirus (H
88 are rare in mammals; however, several human tumor viruses, including the papillomaviruses and the ga
89 ns of transforming proteins from several DNA tumor viruses, including two papillomaviruses and two po
90 s idea, results with several different human tumor viruses indicate that their oncogenic potential de
91 NK cells against different targets including tumor, virus-infected, and immature dendritic cells.
92 teraction with specific ligands expressed on tumor/virus-infected cells, thus contributing to immune
93 papillomavirus (PV) is a double-stranded DNA tumor virus infecting cervix, mouth, and throat tissues.
95 ypes, including wingless-type murine mammary tumor virus integration site (WNT) pathway subtype, Soni
96 cyclin D1 and wingless-related mouse mammary tumor virus integration site 10b (Wnt10b) in 3T3-L1 cell
97 ome inducible by wingless-type mouse mammary tumor virus integration site family member (WNT)/beta-ca
98 here wnt refers to the wingless-type mammary tumor virus integration site family of proteins), that a
99 ween mesenchymal Wingless-type Mouse Mammary Tumor Virus integration site family, member 10B (Wnt10b)
100 tion of Wingless-related MMTV (mouse mammary tumor virus) integration site 3 (WNT3) by ingrowing axon
102 canonical wingless-type MMTV (mouse mammary tumor virus) integration site family (WNT) signaling pat
103 e best-studied oncoproteins encoded by a DNA tumor virus is adenovirus E1A, which modifies the functi
104 establishment of a latent reservoir by human tumor viruses is a vital step in initiating cellular tra
106 sarcoma-associated herpesvirus (KSHV), a DNA tumor virus, is an etiological agent linked to several h
107 rus saimiri (HVS), which is a T-lymphotropic tumor virus, is constitutively targeted to lipid rafts a
109 ions, under the control of the mouse mammary tumor virus long terminal repeat promoter, develop multi
111 alizing CSF-1R antibody in the mouse mammary tumor virus long-terminal region-driven polyoma middle T
112 3beta under the control of the mouse mammary tumor virus-long terminal repeat develop mammary tumors
113 e whey acidic protein (WAP) or mouse mammary tumor virus-long terminal repeat promoters, develop mamm
114 e steroid responsive MMTV-LTR (mouse mammary tumor virus-long terminal repeat), we show that BRG1 and
115 ositions of nucleosomes on the mouse mammary tumor virus LTR, and additionally, we characterized the
117 , our data provide the first evidence that a tumor virus may use a viral protein to interfere with mi
118 results provide new insights into how human tumor viruses may manipulate cellular DNA-damage respons
119 at the oncoproteins encoded by the small-DNA tumor viruses may use this mechanism to induce c-Myc, wh
121 Two other betaretroviruses, mouse mammary tumor virus (MMTV) and human endogenous retrovirus type
122 APOBEC3 restricts infection by mouse mammary tumor virus (MMTV) and murine leukemia virus (MLV) and t
123 , which control infection with mouse mammary tumor virus (MMTV) and murine leukemia virus (MuLV) via
124 on on two different reporters, mouse mammary tumor virus (MMTV) and prostate-specific antigen (PSA).
125 o 97% nucleotide homology with mouse mammary tumor virus (MMTV) and with retrovirus sequences derived
127 l, have suggested that a human mouse mammary tumor virus (MMTV) causes primary biliary cirrhosis (PBC
128 lls stably transfected with an mouse mammary tumor virus (MMTV) chloramphenicol acetyltransferase rep
132 ith sequences derived from the mouse mammary tumor virus (MMTV) envelope glycoprotein, influenza viru
135 with sequences similar to the mouse mammary tumor virus (MMTV) has been shown, but convincing eviden
139 wed that IFN-gamma elicited by mouse mammary tumor virus (MMTV) infection in I/LnJ mice stimulated pr
145 expressing Sim2s driven by the mouse mammary tumor virus (MMTV) long terminal repeat (LTR) promoter w
149 the maximal effect of DEX in a mouse mammary tumor virus (MMTV) luciferase reporter transactivation a
150 otein of the murine retrovirus mouse mammary tumor virus (MMTV) orchestrates the assembly of immature
152 in-remodeling complex, and the mouse mammary tumor virus (MMTV) promoter assembled in an array of cor
153 endent transcription from the murine mammary tumor virus (MMTV) promoter by p65 and E1A was investiga
154 ssion under the control of the mouse mammary tumor virus (MMTV) promoter in a transgenic mouse model
155 sponse was investigated on the mouse mammary tumor virus (MMTV) promoter in different chromatin confi
156 ed human SMO (SmoM2) under the mouse mammary tumor virus (MMTV) promoter in transgenic mice leads to
157 Here, the basic features of mouse mammary tumor virus (MMTV) promoter nucleosomal arrays reconstit
158 the interaction of PR with the mouse mammary tumor virus (MMTV) promoter reconstituted into chromatin
159 otein under the control of the mouse mammary tumor virus (MMTV) promoter results in mammary gland hyp
161 ranscriptional activation of a mouse mammary tumor virus (MMTV) promoter-driven luciferase construct
162 etion of Ppm1d in mice bearing mouse mammary tumor virus (MMTV) promoter-driven oncogenes Erbb2 (also
168 orally transmitted retrovirus mouse mammary tumor virus (MMTV) requires the intestinal microbiota fo
169 emogenic virus is a variant of mouse mammary tumor virus (MMTV) that causes thymic lymphomas rather t
170 have shown that CDP represses mouse mammary tumor virus (MMTV) transcription in tissue culture cells
172 B leukemogenic virus (TBLV), a mouse mammary tumor virus (MMTV) variant, often induces T-cell leukemi
173 ommon integration site for the mouse mammary tumor virus (MMTV) was identified (designated Int7) in f
174 a transcriptional repressor of mouse mammary tumor virus (MMTV), a betaretrovirus that is a paradigm
175 a, c-myc, and those encoded by mouse mammary tumor virus (MMTV), a glucocorticoid-responsive retrovir
176 shows for the first time that mouse mammary tumor virus (MMTV), a mammalian retrovirus that assemble
178 Many retroviruses, including mouse mammary tumor virus (MMTV), are transmitted most efficiently thr
179 te sheep retrovirus (JSRV) and mouse mammary tumor virus (MMTV), as well as many endogenous retroviru
180 ry-specific deletion inhibited mouse mammary tumor virus (MMTV)- PyMT- and MMTV- Wnt1-driven mammary
182 s as judged by findings with a mouse mammary tumor virus (MMTV)-c-rel transgenic mouse model, in whic
183 ammary epithelial cells of the mouse mammary tumor virus (MMTV)-Cre Brca1 conditional exon 11 deletio
186 of HER2/Neu in breast cancer, mouse mammary tumor virus (MMTV)-Her2/neu transgenic mice that develop
187 2 overexpression, we generated mouse mammary tumor virus (MMTV)-Hoxb7 transgenic mice, and then cross
188 creases mammary cancer risk in mouse mammary tumor virus (MMTV)-infected females even after multiple
189 e previously reported a 660-bp mouse mammary tumor virus (MMTV)-like env gene sequence in approximate
194 mor formation in xenograft and mouse mammary tumor virus (MMTV)-neu mouse models in a manner associat
195 PA), inhibits lung metastases in the mammary tumor virus (MMTV)-Neu transgenic mouse breast cancer mo
196 ogenic signaling in the NeuYD [mouse mammary tumor virus (MMTV)-Neu(ndl)-YD5] mammary tumor model.
198 st tumorigenesis, we generated mouse mammary tumor virus (MMTV)-NeuNT transgenic mice lacking one or
199 crossing the mutation into the mouse mammary tumor virus (MMTV)-polyoma virus middle T (PyV-mT) trans
200 ation of mammary tumors in the mouse mammary tumor virus (MMTV)-polyoma virus middle T (PyVT) genetic
201 /+) mice were crossed with the mouse mammary tumor virus (MMTV)-Polyoma virus middle T antigen (PyMT)
202 F transcription factors in the mouse mammary tumor virus (MMTV)-polyomavirus middle T oncoprotein (Py
203 tant knock-in (R175H) mice and mouse mammary tumor virus (MMTV)-Wnt-1 transgenic (mWnt-1) mice to spe
205 expressed in mammary tumors of mouse mammary tumor virus (MMTV)-Wnt1-transgenic mice and in aggressiv
210 ted c-neu oncogene driven by a mouse mammary tumor virus (MMTV-neu) in vivo, we show that ErbB2 overe
211 rous, ErbB2/Neu-overexpressing mouse mammary tumor virus (MMTV-Neu) mice have shown that parity induc
212 The absence of endogenous mouse mammary tumor viruses (MMTVs) in the congenic mouse strain, BALB
213 illustrates a distinct mechanism by which a tumor virus modulates vasculature to promote tumorigenes
214 relative to MCC patients with virus-positive tumors, virus-negative MCC patients had significantly in
216 celerated tumor progression in mouse mammary tumor virus/neu transgenic mice by inhibiting apoptosis
217 terminal (Cys(2)HisCys) ZBD of Mouse Mammary Tumor Virus nucleocapsid protein (MMTV NCp10) were resis
218 ions in chromosome 22, including the chicken tumor virus number 10 regulator of kinase (Crk)-like (Cr
225 ors have developed, we use the mouse mammary tumor virus-Polyoma Middle T (MMTV-PyMT), which mimics R
227 ent, we established cohorts of mouse mammary tumor virus-polyoma middle T (PyMT) PAR1(-/-) and PAR2(-
228 l of breast cancer, MMTV-PyMT (mouse mammary tumor virus-polyoma middle T antigen), with Cav-1 (-/-)-
231 ls of Kiss1r gene knockout and mouse mammary tumor virus-polyoma virus middle T antigen (MMTV-PyMT)-i
232 itumor response, we engineered mouse mammary tumor virus-polyoma virus middle T antigen mice with end
233 increased pAkt levels in total mouse mammary tumor virus-polyoma virus middle T antigen tumor lysates
234 enesis, we generated wild-type mouse mammary tumor virus/polyoma middle-T (WT/PyMT) and AIB3(+/-)/PyM
235 mice in the background of the mouse mammary tumor virus/polyoma virus middle T oncogene (MMTV-PyMT)
236 d AIB1(-/-) mice harboring the mouse mammary tumor virus-polyomavirus middle T (PyMT) transgene.
237 table (4T1) and autochthonous (mouse mammary tumor virus-polyomavirus middle T Ag (MMTV-PyMT)) mouse
238 br2MGKO mice were mated to the mouse mammary tumor virus-polyomavirus middle T antigen (PyVmT) transg
240 2-myristate-13-acetate-induced mouse mammary tumor virus promoter activity and phorbol 12-myristate 1
242 e-dependent PR activation of a mouse mammary tumor virus promoter in both prostate (PC-3) and breast
244 MTA1 under the control of the mouse mammary tumor virus promoter long terminal repeat were generated
245 te hSwi-Snf complexes bound to mouse mammary tumor virus promoter nucleosomal arrays, a natural targe
247 ear factor 1 (NF1) to bind the mouse mammary tumor virus promoter organized as regular chromatin in v
248 epressed the activation of the mouse mammary tumor virus promoter related to overexpression of the tr
249 receptor, to a tandem array of mouse mammary tumor virus promoter sites in live cells, obtaining an e
250 (KDACis) potently repress the mouse mammary tumor virus promoter through transcriptional mechanisms
251 oma middle T antigen under the mouse mammary tumor virus promoter were combined with mice that have d
252 C-->U substitution within the mouse mammary tumor virus promoter, one located within each GRE half-s
253 ncers in mice transgenic for a mouse mammary tumor virus promoter-driven polyomavirus middle T antige
254 A transcriptionally inert Mouse Mammary Tumor Virus promoter-region nucleosome (MMTV-D) has grea
262 were performed on a mutant of mouse mammary tumor virus pseudoknot (VPK), for which an NMR structure
263 ity of the folded structure of mouse mammary tumor virus pseudoknot in the presence of different amou
264 ucleotides (ASOs) in the MMTV (mouse mammary tumor virus)-PyMT mouse mammary carcinoma model results
266 d utilizes a conditional allele of the avian tumor virus receptor A (TVA), which allows infection of
270 ncreasing evidence that the transforming DNA tumor virus simian virus 40 (SV40) is associated with hu
273 are tolerized to an endogenous mouse mammary tumor virus superantigen either by deletion or TCR revis
276 KS.IMPORTANCE Here we show that HHV-8, a DNA tumor virus that causes Kaposi's sarcoma, infects three
278 ted herpesvirus (KSHV) is a lymphotropic DNA tumor virus that induces Kaposi's sarcoma and AIDS-relat
281 ) and Epstein-Barr virus (EBV) are human DNA tumor viruses that express nuclear antigens [latency-ass
282 so through mechanisms distinct from classic tumor viruses that express transforming viral oncoprotei
283 eplication-competent exogenous mouse mammary tumor viruses that failed to induce mammary tumors in su
287 the mid-1970s, the molecular basis by which tumor viruses transform cells into a malignant state was
289 also the first demonstration of a human DNA tumor virus upregulating TLR3, a TLR that thus far has b
290 e provided a mechanistic framework for how a tumor virus using the epigenetic machinery can act in a
291 d AIB1(-/-) mice harboring the mouse mammary tumor virus/v-Ha-ras (ras) transgene that induces breast
292 In the middle of the 20th century, animal tumor viruses were heralded as possible models for under
293 uman papillomaviruses (HPVs) are small dsDNA tumor viruses, which are the etiologic agents of most ce
294 the carcinogenic properties of various human tumor viruses, which, in aggregate, are etiologically as
295 gonist of the wingless-related mouse mammary tumor virus (WNT) signaling pathway, is one endometrial
296 B-231 breast cancer cells, and mouse mammary tumor virus-Wnt-1 mammary tumor-derived cells, implicati
299 r efficacy was shown using the mouse mammary tumor virus-Wnt1 tumor model under dosing conditions tha
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