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1 umor growth in an EZH2-dependent manner, and tumors bearing a non-GNA-interacting C668S-EZH2 mutation
2 (MAPK) kinase (MEK) can induce regression of tumors bearing activating mutations in the Ras pathway b
3 d with (64)Cu, and administered to normal or tumor-bearing aged, female, retired breeder Sprague-Dawl
5 Bone marrow and splenic cells extracted from tumor-bearing and control mice (n= 3/group) were coincub
6 sing (18)F-FDG was successfully performed on tumor-bearing and non-tumor-bearing mice, as well as on
8 line uptake of (18)F-AH113804, determined in tumor-bearing animals after 10 d, was approximately 2-fo
9 early as 6 d after surgery in the recurrent tumor-bearing animals and exhibited significantly higher
10 d cells were isolated from either healthy or tumor-bearing animals and injected into tumor-bearing mi
11 odistribution and in vivo PET imaging in non-tumor-bearing animals as well as in KB-3-1 and COLO-205
15 ng tumor cells were significantly reduced in tumor-bearing animals when treated with anti-IL6R antibo
16 t manner, modulated cytokine blood levels in tumor-bearing animals, and impaired tumor progression vi
23 es were performed using CD-1 nu/nu and LNCaP tumor-bearing CB-17 severe combined immunodeficiency mic
27 milar to non-targeted liposomes in syngeneic tumor-bearing FVB mice and C-LPP liposomes reduced doxor
28 uced by experimenter-induced movement of the tumor-bearing hindlimb with a context produces condition
30 id-derived suppressor cells (MDSC) expand in tumor-bearing hosts and play a central role in cancer im
32 oup of immature myeloid cells that expand in tumor-bearing hosts in response to soluble factors produ
34 We hypothesized that NO producing MDSC in tumor-bearing hosts would inhibit DC antigen presentatio
35 cient in their ability to accumulate MDSC in tumor-bearing hosts, demonstrated reduced MDSC accumulat
36 these effects reduced mMDSC accumulation in tumor-bearing hosts, limiting the outgrowth of KRas-driv
41 feel that this approach should be tested in tumor-bearing human patients in combination with antitum
42 ALT-803 lost its antimyeloma activity in tumor-bearing IFN-gamma knockout mice but retained the a
43 optive transfer of T cells from DLL1-treated tumor-bearing immunocompetent hosts into tumor-bearing S
46 s (MDSC) contribute to immune suppression in tumor-bearing individuals and are a major obstacle to ef
48 rmacologic inhibition of the PI3K pathway in tumor-bearing Kit(V558Delta/+) mice with the dual PI3K/m
49 an be used to ablate target tissues in a non-tumor-bearing large-animal model while selectively spari
52 (FLR), portal vein embolization (PVE) of the tumor-bearing liver is used to induce contralateral live
53 breast adenocarcinoma tumors had normal non-tumor-bearing liver treated with RFA (70 degrees C x 5 m
54 ystemically delivering TTK siRNAs to already tumor-bearing liver, limits intrahepatic spread of liver
59 stribution of (18)F-LMI1195 was evaluated in tumor-bearing MENX mut/mut rats (n = 10) and control MEN
60 nd lymphocyte proliferation was increased in tumor-bearing MerTK-/- mice compared with tumor-bearing
61 tion of p-Akt in PTEN-deficient PC3 prostate tumor bearing mice after oral administration and showed
62 PDLA micelles or nanoemulsions to pancreatic tumor bearing mice resulted in complete tumor resolution
66 r intravenous treatment of RDLPNPs into Hela tumor bearing mice, fluorescent (from DiR) and enhanced
72 umumab- versus IgG1-treated COLO205 and HT29 tumor-bearing mice (P = 0.104 and 0.779, respectively) a
73 ssing VEGF-B or control vector to normal and tumor-bearing mice 1 wk before DOX treatment, using dose
75 or-infiltrating PD-L1(+) cells isolated from tumor-bearing mice also exerted morphology of tumor-asso
76 he peptide hormone Angiotensin II (AngII) in tumor-bearing mice amplifies self-renewing hematopoietic
77 ite elevated plasma levels of VEGFA in fs120 tumor-bearing mice and a dependence on VEGF receptor 1 a
79 n be detected in EVs purified from plasma of tumor-bearing mice and from conditioned media of culture
81 R5 ligand interactions increased survival of tumor-bearing mice and was associated with reduced migra
83 did not affect circulating levels of MDSC in tumor-bearing mice because the decreased apoptotic rate
85 onsistently upregulated in TLR5-unresponsive tumor-bearing mice but only accelerates malignant progre
86 ry differentiation of therapeutic T cells in tumor-bearing mice by introducing molecular switches tha
87 tudy, we demonstrate that IL-2c treatment in tumor-bearing mice can enhance NK cell and tumor-specifi
88 sion was significantly reduced in MDSCs from tumor-bearing mice compared to non-tumor-bearing hosts.
89 greater antitumor efficacy in EG.7 and TC-1 tumor-bearing mice compared to the control (p < 0.01).
90 d lower viability and a shorter half-life in tumor-bearing mice compared with neutrophils and monocyt
92 administration of the bioorthogonal IONPs in tumor-bearing mice demonstrated the signal-enhancing abi
95 ng larger tumors, the Arg-knockdown (Arg KD) tumor-bearing mice exhibit significant reductions in tum
96 Dendritic cells (DCs) from NK cell-depleted tumor-bearing mice exhibited a more mature phenotype.
98 than non-tumor-bearing mice, suggesting that tumor-bearing mice experience a greater degree of cold-s
99 that the pan-BET inhibitor (+)-JQ1 protects tumor-bearing mice from body weight loss and muscle and
101 n occupancy and gene expression in young and tumor-bearing mice identified a set of shared targets fo
103 siRNA-mediated LPP silencing in ovarian tumor-bearing mice improved paclitaxel delivery to cance
105 c model and improved the overall survival of tumor-bearing mice in the GL26 syngeneic glioma model.
106 Depletion of CD8(+) T cells or NK cells in tumor-bearing mice indicates that both cell types initia
107 he increased production of angiotensin II in tumor-bearing mice induces the expansion of macrophage p
109 at doxorubicin (DOX) treatment of 4T1 breast tumor-bearing mice led to the induction of IL-13R(+)miR-
110 generated by treating HER2(+)/PIK3CA(H1047R) tumor-bearing mice long term with the drug combination.
114 h increased monoclonal (M) protein (g/dL) in tumor-bearing mice over time (3.29 +/- 0.58 at week 0 an
117 positive PC-3 PIP and PSMA-negative PC-3 flu tumor-bearing mice revealed that (86)Y- 4-6: had high si
118 ongitudinal analysis of circulating ALCAM in tumor-bearing mice revealed that shedding of tumor, but
119 ing lymph nodes of IL-12 plus GM-CSF-treated tumor-bearing mice revealed that whereas IFN-gamma induc
120 Notably, in temperature preference studies, tumor-bearing mice select a higher ambient temperature t
121 The L-band EPR studies performed in breast tumor-bearing mice show a significant difference in extr
123 Peritoneal lavage fluids from CREB-inhibited tumor-bearing mice showed a significantly reduced total
125 jugated Au-tripods (RGD-Au-tripods) to U87MG tumor-bearing mice showed PAI contrasts in tumors almost
127 stration of PNC-gel extended the survival of tumor-bearing mice significantly better than Taxol, but
130 esultant FA-3DNA-siHuR conjugates to ovarian tumor-bearing mice suppressed tumor growth and ascites d
133 extracellular traps (NET), in the kidneys of tumor-bearing mice that were completely absent from heal
135 one marrow-derived cells (BMDCs), we exposed tumor-bearing mice to chemotherapeutic agents and evalua
136 logy model of VEGF transport and kinetics in tumor-bearing mice to include a tumor compartment whose
138 nosuppressed (Nu/Nu) squamous cell carcinoma tumor-bearing mice treated post-IR with the constitutive
141 l as their efficacy in extending survival in tumor-bearing mice underscores their potential as a radi
144 claudin-low tumors, and Tregs isolated from tumor-bearing mice were able to suppress effector T cell
145 Experiments in cell cultures as well as in tumor-bearing mice were analyzed to determine the role o
150 e tumor size reached 0.5-0.8 cm in diameter, tumor-bearing mice were systemically administered (64)Cu
153 y, in the murine model, approximately 40% of tumor-bearing mice were tumor-free after a single treatm
154 Summary In the study of Zhang et al (1), tumor-bearing mice were vaccinated with magnetically lab
155 acid metabolism, and methylation, identified tumor-bearing mice with 100% accuracy, and also accurate
159 essing mouse model of melanoma, treatment of tumor-bearing mice with alphaGC/OVA-loaded exosomes decr
161 1 immunity in CNS tissues, we infected GL261 tumor-bearing mice with attenuated rabies virus (RABV).
162 istribution studies were performed in LS174T tumor-bearing mice with AVP04-07-TCO(n) (where n indicat
163 ollowing transplantation, and inoculation of tumor-bearing mice with bFGF markedly inhibits tumor gro
165 e observed that the single-dose treatment of tumor-bearing mice with DMA 2 hours before 8 Gy total bo
166 omparison of non-draining LNs and spleens of tumor-bearing mice with LNs and spleens from naive mice
169 efects in tumors can be reversed by treating tumor-bearing mice with multivalent forms of the Notch r
170 ncing in MCL cells and prolonged survival of tumor-bearing mice with no observed adverse effects.
171 s mechanism of action is preserved, to treat tumor-bearing mice with otherwise lethal levels of chemo
174 y decreased tumor weight and splenomegaly in tumor-bearing mice with reduced accumulation of polymorp
175 P78-regulated metabolite changes by treating tumor-bearing mice with tamoxifen and/or linoleic acid.
176 ted blood, splenic and intratumoral MDSCs in tumor-bearing mice without affecting proinflammatory imm
178 omparison with controls after injection into tumor-bearing mice, and promoted DC maturation, leading
179 cessfully performed on tumor-bearing and non-tumor-bearing mice, as well as on controls bearing sites
180 foundly block naive CD8(+) T cell priming in tumor-bearing mice, but actually increased the number of
181 d in MDSCs isolated from cancer patients and tumor-bearing mice, but not in control neutrophils or mo
183 ngiogenesis, leading to improved survival of tumor-bearing mice, even when this interaction was intac
184 ection of the various SPIO compositions into tumor-bearing mice, inductively coupled plasma mass spec
187 An OV engineered to express FGF2 was safe in tumor-bearing mice, showed improved therapeutic efficacy
188 select a higher ambient temperature than non-tumor-bearing mice, suggesting that tumor-bearing mice e
189 t those isolated from the spleen of the same tumor-bearing mice, suppress T cell proliferation and ex
193 e prolonged survival but did not cure HDLM-2 tumor-bearing mice, whereas BV combined with ruxolitinib
194 D-1-expressing cells extends the survival of tumor-bearing mice, whereas free drugs have no effect at
195 o(LA)8-PTX induced tumor regression in A549 tumor-bearing mice, whereas PTX delayed tumor growth.
196 high-dimensional analysis of immune cells in tumor-bearing mice, which eliminates gating biases and i
197 (64)Cu-DOTA-cetuximab in KRAS-mutated HCT116 tumor-bearing mice, with and without cisplatin, which up
257 in vivo studies using LS174T s.c. xenograft tumor bearing mouse, selective and significantly augment
263 atment of orthotopic human pancreatic cancer tumor-bearing NSG mice with activated NK cells led to si
265 all-animal PET experiments were performed on tumor-bearing nude mice after subcutaneous injection of
270 average elastic moduli of non-neoplastic and tumor-bearing optic nerves were approximately 3 and appr
271 nistration of into hepatic arteries of a VX2 tumor-bearing rabbit under fluoroscopy, followed by subs
273 injections of rat hepatoma cells (H4IIE); 24 tumor-bearing rats (mean tumor diameter, approximately 1
276 a and CD11b mRNA expression were elevated in tumor-bearing rats, whereas Ido expression was reduced.
277 tory pathways are potentiated, or primed, in tumor-bearing rats, which may exacerbate future negative
281 greater in hippocampus and frontal cortex of tumor-bearing relative to tumor-free rats, IkappaBalpha
282 ted tumor-bearing immunocompetent hosts into tumor-bearing SCID-NOD immunocompromised mice attenuated
283 in PD-L1-positive, PD-L1-negative, and mixed tumor-bearing severe combined immunodeficiency mice.
284 opeptide alone or after coinjection of PA in tumor-bearing severe combined immunodeficient (SCID) mic
285 the in vivo antitumor effects of MEDI-575 in tumor-bearing severe combined immunodeficient (SCID) mic
286 -4 radioconjugates were investigated in PC-3 tumor-bearing severely combined immunodeficient mice.
287 ify transcriptional programs associated with tumors bearing specific genetic driver alterations.
288 epletion of CD4(+) but not CD8(+) T cells in tumor-bearing subjects reversed the inhibitory effects o
289 ve change in reporter levels also identified tumor-bearing subjects, and a receiver operator-characte
297 ash mice into line 1 alveolar cell carcinoma tumor-bearing wild-type littermates leads to enhanced tu
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