ライフサイエンスコーパス: tumour cell line

1 ectopically in the 833K testicular germ cell tumour cell line.

2 ollection of 533 genetically annotated human tumour cell lines.

3 in reaction (RT-PCR) in Ewing's sarcoma cell tumour cell lines.

4 y in glyoxalase 1-linked multidrug resistant tumour cell lines.

5 as that influence the homing of a variety of tumour cell lines.

6 d was hypermethylated in primary tumours and tumour cell lines.

7 wnregulation of BLU transcript expression in tumour cell lines.

8 % neuroblastoma and 80% nasopharyngeal (NPC) tumour cell lines.

9 ession was downregulated in a subset of lung tumour cell lines.

10 NORE1B promoter was unmethylated in the same tumour cell lines.

11 nasopharynx, as well as in a subset of lung tumour cell lines.

12 the well-defined 833K and GCT27 human testis tumour cell lines.

13 pendent growth of two out of four colorectal tumour cell lines.

14 o the genomic instability of some colorectal tumour cell lines.

15 this heterogeneity can differ between human tumour cell lines.

16 14(ARF) expression and p53 function in human tumour cell lines.

17 NA and the persyn gene in breast tumours and tumour cell lines.

18 og XRCC2 (342delT) found in an HRR-defective tumour cell line, 342delT was introduced into HRR profic

19 RASSF2 was frequently methylated in breast tumour cell lines (65%, 13/20) and in primary breast tum

20 hypermethylated in a majority of colorectal tumour cell lines (89%) and in primary colorectal tumour

21 We identified a tumour cell line, 97-7, expressing the most common FGFR3

22 DH LRES patterns are reflected in colorectal tumour cell lines; adenoma cell lines are not methylated

23 uld be switched back on in methylated breast tumour cell lines after treatment with 5'-aza-2'deoxycyt

24 F2A expression was reactivated in methylated tumour cell lines after treatment with 5-aza 2-deoxycyti

25 (RASSF1A) was absent in the majority of lung tumour cell lines analysed.

26 1) fusion were identified in 4 of 43 bladder tumour cell lines and 2 of 32 selected tissue samples in

27 essed in some but not all breast and ovarian tumour cell lines and also in a glioma cell line.

28 analysed BLU promoter methylation status in tumour cell lines and detected promoter region hypermeth

29 n the majority of primary lung tumours, lung tumour cell lines and in a variable percentage of breast

30 ation has been previously detected in breast tumour cell lines and in colon tumours; here, we report

31 xpression of erbB-4 mRNA in a range of human tumour cell lines and in normal and malignant breast tis

32 reduces MST2 levels, in addition colorectal tumour cell lines and primary tumours with low RASSF2 le

33 the essential oil displayed cytotoxicity on tumour cell lines and showed IC50 values ranging from 24

34 cyte polarity; H.sapiens HEM45, expressed in tumour cell lines and uterus and regulated by oestrogen;

35 Natural killer (NK) cells attack many tumour cell lines, and are thought to have a critical ro

36 pression correlates with chemo-resistance of tumour cell lines, and reductions in Bcl-2 increase sens

37 Instead, MMR-defective tumour cell lines are also defective in homologous recom

38 Here we show that MMR-deficient tumour cell lines are highly sensitive to the toxic effe

39 45gamma gene was also found in the pituitary tumour cell line AtT20.

40 the antitumour potential was tested in human tumour cell lines (breast, lung, colon, cervical and hep

41 the antitumour potential was tested in human tumour cell lines (breast, lung, colon, cervical and hep

42 f breast carcinoma tissue samples and breast tumour cell lines, but not normal mammary tissue or beni

43 LM and CLW showed growth inhibition of human tumour cell lines by 0-46%.

44 d human NKG2D ligands are upregulated in non-tumour cell lines by genotoxic stress and stalled DNA re

45 Established cervical tumour cell lines carrying HPV were unable to communicat

46 the range of transcripts encoded in a breast tumour cell line, compared to normal breast, suggested t

47 mour viruses SV40 or adenovirus, or in human tumour cell lines, contained very low levels of or no de

48 h provides access to the European Searchable Tumour Cell-Line Database, a cell bank of immunologicall

49 h provides access to the European Searchable Tumour cell-line database, a cell bank of immunologicall

50 h provides access to the European Searchable Tumour Cell-Line Database, a cell bank of immunologicall

51 Thus, tumour cell lines derived using this methodology represe

52 Importantly, the 25 new ovarian tumour cell lines described here retain the genomic land

53 ents that exhibit cytotoxic activity against tumour cell lines due to their ability to inhibit topois

54 A subset of tumour cell lines exhibit dependence on MCL1 expression

55 Conversely, in lung tumour cell lines expressing Kras(G12D) and lacking p53,

56 of DNA synthesis and Ras ADP-ribosylation in tumour cell lines expressing normal and mutant Ras revea

57 NHEJ was found in established tumour cell lines from different originating tissues, th

58 Somatic mutation data from tumours and tumour cell lines have been mapped onto the crystal stru

59 ping homozygous deletions in lung and breast tumour-cell lines have defined a minimal critical 120 kb

60 l extracts exerted cytotoxicity against some tumour cell lines (HeLa, MCF7, HT-29), besides the promi

61 xpression of TRF1 in the telomerase-positive tumour-cell line HT1080 resulted in a gradual and progre

62 e cell model as well as in the human colonic tumour cell line, HT29, using whole-cell voltage clamp.

63 inhibitors of the proliferation of numerous tumour cell lines in culture and of murine syngeneic tum

64 also observed effective killing of lymphoid tumour cell lines in vitro following exposure to ALX, al

65 tected in mononuclear leukocytes in vivo and tumour cell lines in vitro.

66 nstitutively high levels in many tumours and tumour cell lines, indeed this phenomenon has been used

67 esent evidence that p53 protein stability in tumour cell lines is determined by association with the

68 ults show that a low XPA level in the testis tumour cell lines is sufficient to explain their poor ab

69 l DNA (mtDNA) were introduced into two human tumour cell lines lacking mtDNA.

70 The prostate tumour cell line LNCaP was transfected with this vector

71 e the fidelity of DSB repair in the prostate tumour cell line LNCaP, the bladder tumour cell line MGH

72 t the thymidine sensitivity of MMR-deficient tumour cell lines may be a consequence of defects in the

73 prostate tumour cell line LNCaP, the bladder tumour cell line MGH-U1 and a radiosensitive subclone S4

74 er region of DUTT1 gene in the HTB-19 breast tumour cell line (not expressing DUTT1) showed complete

75 ther murine tissues, as well as in six human tumour cell lines of epithelial origin, including two co

76 here that expression of mouse mutant p53 in tumour cell lines of this type results in high levels of

77 cells, indicating possible dependence of the tumour cell line on mutant FGFR3.

78 Currently available human tumour cell line panels consist of a small number of lin

79 ls using STC-1, a mouse intestinal endocrine tumour cell line, previously shown to release cholecysto

80 HA-DBCCR1 in NIH3T3 cells and human bladder tumour cell lines resulted in suppression of proliferati

81 ine NKG2D ligands Rae1beta or H60 in several tumour cell lines results in potent rejection of the tum

82 Northern and RT-PCR analysis of a panel of tumour cell lines showed that LPHH1 expression was varia

83 log XRCC2 found in the MMR-deficient uterine tumour cell line SKUT-1 can confer thymidine sensitivity

84 Tumour cell lines stably transfected with LEF1(DN) or AP

85 a probable germline mutation in a pancreatic tumour cell line suggests a role for BRCA2 in susceptibi

86 transcript is expressed in the human breast tumour cell line T-47D.

87 expressed channel protein in a human colonic tumour cell line T84.

88 Normal primary cells and tumour cell lines that express wild-type chfr exhibited

89 In contrast, the tumour cell lines that had lost chfr function entered me

90 gen of simian virus 40 (SV40 T-Ag) and human tumour cell lines that lack a functional retinoblastoma

91 our cells and that this effect is selective; tumour cell lines that overexpress PPM1D are sensitive t

92 that selectively reduces viability of human tumour cell lines that overexpress PPM1D.

93 In a panel of 16 human tumour cell lines, the anti-proliferative activity of AZ

94 e demonstrate that in amoeboid-like invasive tumour cell lines, the v-SNARE, VAMP3, regulates deliver

95 Interestingly, exposure of epithelial tumour cell lines to ALX in vitro resulted in potent act

96 Expression was recovered in tumour cell lines treated with 5-aza 2-deoxycytidine.

97 epithelial cell line MCF10A and the uMUC1(-) tumour cell line U87.

98 lysed a Birt-Hogg-Dube patient-derived renal tumour cell line (UOK257) that is devoid of the Birt-Hog

99 level of specific genes in a panel of human tumour cell lines using modified Southern blotting metho

100 hermore, constitutive ligand expression by a tumour cell line was inhibited by targeting short interf

101 DNA synthesis in some tumour cell lines was completely resistant to the anti-R

102 NORE1A expression in tumour cell lines was reactivated after treatment with a

103 C, 3/17 NSCLC, 1/6 colorectal and 3/9 kidney tumour cell lines, while NORE1B promoter was unmethylate

104 rest were found following treatment of human tumour cell lines with serum, 12-O-tetradecanoyl-phorbol

105 igh expression of STK15 mRNA was detected in tumour cell lines without evidence of gene amplification