ライフサイエンスコーパス: tune

1 als but can become detrimental if not finely tuned.

2 30 dB and was broad-band rather than sharply tuned.

3 ange of stimuli to which they are said to be tuned.

4 ts and the emergence of cortical orientation tuning.

5 ing resonators enables continuous wavelength tuning.

6 n be exploited as a vehicle for conductivity tuning.

7 tromechanical platform to demonstrate active tuning.

8 improve visuospatial perception or alter its tuning.

9 which are not consistent with their monaural tuning.

10 be considered as new therapeutic targets to tune adequate physiological processes in the gut in heal

11 tion during a period of neurobehavioral fine-tuning (age 22-36 years).

12 The measurements show that MIM tuning, aided by a digital tunable attenuator (DTA), can

13 lar albumin recycling and the possibility to tune albumin-based therapeutic effects by FcRn-binding a

14 previously identified as a hotspot of shape-tuning alleles involved in wing mimicry.

15 hell architectures offer an effective way to tune and enhance the properties of noble-metal catalysts

16 dictably to surface mutation, allowing us to tune and intermix the protein's behavior at will.

17 gical function, these findings point to fine-tuned and interdependent functional roles of specific pr

18 hat the spike burst coding is size and speed-tuned and is selectively modulated by motion parallax-th

19 trate that CT at the interface of NCs can be tuned and promoted by metal ion doping.

20 quencies of the responses were tonotopically tuned and ranged from 384 to 668 Hz.

21 and-pass structures that do not require fine-tuning and are robust against environmental and cellular

22 karyote transition allows for increased fine-tuning and broadening of Hsp70 function in eukaryotes.

23 r, we describe procedures for the following: tuning and calibrating a SYNAPT High-Definition MS (HDMS

24 from 6-membered P,N-ligands that facilitates tuning and enables ligand evolution to address issues of

25 over, socialtaxis does not require parameter tuning and is highly robust to sensory and behavioral no

26 n between interaural mismatches in frequency tuning and ITD tuning during in vivo loose-patch (juxtac

27 re selectively suppressed using lithographic tuning and single mode operation of the multi-mode laser

28 ural discriminability, sharpened orientation tuning, and led to higher contrast sensitivity.

29 eld-induced state in the vicinity of a field-tuned antiferromagnetic quantum critical point at Hc app

30 al plasticity mechanism for dynamically fine-tuning AP conduction velocity, which potentially has wid

31 eld, thereby providing a practical route for tuning appropriate materials to a quantum critical point

32 en described, these processes and their fine-tuning are not fully understood.

33 ere the authors demonstrate refractive index tuning at mid-infrared wavelengths using temperature-dep

34 cy of lamellipodia is determined by a finely tuned balance between lamellipodial and cytosolic actin

35 analysis, we also determined the orientation-tuning bandwidth of correlated activity between pairs of

36 ough which parallel biogenic amine signaling tunes behavior appropriately to nutrient conditions.SIGN

37 were able to, for the first time, precisely tune both the size and width of the AuNP frame.

38 g ordering, and the array periodicity can be tuned by adjusting the growth conditions.

39 these materials in the visible range can be tuned by changing the number of inorganic atomic layers

40 es of metal-organic frameworks (MOFs) can be tuned by chemical functionalization of the organic ligan

41 ture and elastic properties can be precisely tuned by controlling the geometry of the elemental build

42 e dipoles and surface plasmons can be finely tuned by coupling the dye molecules to specific sites of

43 ctronic properties of the cubane are readily tuned by exchange of the OAc(-) ligand for Cl(-) (1-Cl),

44 first evidence that HTR4 expression is fine-tuned by miRNAs, and that this regulation is impaired ei

45 he ligand binding pockets are allosterically tuned by monoprotonation of the tren unit.

46 a CPG in which precise premotor rhythms are tuned by motor neuron activity.SIGNIFICANCE STATEMENT Ce

47 Because T cell differentiation is finely tuned by multiple positive and negative regulatory signa

48 s of ESX-1 substrates in M. marinum are fine-tuned by negative feedback control, linking the expressi

49 Thus, the ER redox poise is tuned by reciprocal control of glutathione import and Er

50 the LLPS process is directly and sensitively tuned by salt concentration and temperature, implying it

51 The electron density at the bridge was tuned by substituents with different electron donating o

52 These conformational states are finely tuned by substrate availability and purine balance, whil

53 or electrons, but their redox potentials are tuned by the choice of ligand at Mn.

54 Ga0.25 As quantum wells, which indeed can be tuned by the indium composition, suggest that the Nb-In0

55 intensities of these nanoscale films can be tuned by the number of deposition steps.

56 rents promote active diffusion that could be tuned by the parameters of the external excitation field

57 e plasmonic response of the nanoarray can be tuned by the proper choice of GNR size to overlap the fl

58 ed quantum wells wherein the band gap can be tuned by varying the perovskite-layer thickness, which m

59 The efficiency of an mRNA can be tuned by varying the ribosome binding sites controlling

60 residues and Kme3 plays an important role in tuning cation-pi-mediated Kme3 recognition.

61 R complexes are orchestrated by several fine-tuned cellular processes that encompass (a) synthesis of

62 g was broad and did not match auditory nerve tuning characteristics.

63 a tightly regulated process requiring finely tuned complex interactions between different cell types,

64 be a mechanism by which the cell downwardly tunes CRP-dependent Class II promoter activity, whilst e

65 The good performance of the tuned Cu/Ru catalyst is attributed to changes in the ele

66 out the role of covariability among neurons, tuning curve shape, etc.

67 defined subpopulation of neurons with strong tuning-curve alignment, suggesting that it contains a hi

68 assumptions, we show that sensory and motor tuning curves for premovement preparatory activity do no

69 to rescaling of monotonic stimulus intensity tuning curves, but may rather represent a canonical feat

70 cification, the underlying mechanism of fine-tuning double flower formation remains largely unclear.

71 okine-consuming cells, a parameter that gets tuned during immune responses.

72 ntate granule cells in vivo, exhibit spatial tuning during head-fixed spatial navigation, and undergo

73 aural mismatches in frequency tuning and ITD tuning during in vivo loose-patch (juxtacellular) record

74 d heterogeneous catalyst design through fine-tuned edge-site environments of the Co centers.

75 s study demonstrates a promising approach to tune electrocatalytic activity and selectivity of metal

76 ecular details of this synchronized and fine-tuned energy conversion mechanism are not fully understo

77 ts to adapt to changing environments by fine-tuning energy production in leaves and the availability

78 omputational models proposing that attention tunes feature selectivity in visual cortex through backw

79 We propose a novel algorithm for tuning fixation saccades in flies.

80 from elements whose combination need not be tuned for dynamic stability.

81 The hyPAD can be tuned for optimal performance by adjusting the applied v

82 Each subtype ensemble is also tuned for rotation.

83 linear sums of groups of neurons (channels) tuned for visual stimulus properties.

84 rival times, as predicted from the frequency tuning for either ear, and the actual best difference.

85 We show that vestibular signals stabilize tuning for heading in neurons with congruent visual and

86 sin activity that likely reflect specialized tuning for localized cytoskeletal determinants, whereas

87 ar signals enhance the separability of joint tuning for object motion and self-motion.

88 heading preferences, whereas they stabilize tuning for object motion in neurons with discrepant pref

89 tance), and reduction of the gain of feature tuning for partial face stimuli compared to whole face s

90 We show that Hec1 tail phosphorylation tunes friction along polymerizing microtubules and yet d

91 In these mixtures, the phase behavior can be tuned from a mixed state to a coexistence of a liquid-cr

92 a non-metallic TI whose carrier type can be tuned from n to p across the charge neutrality point.

93 l cluster, providing a noncovalent method of tuning fullerene electronics.

94 on of complex stackings used to introduce or tune functionality, but the accessible layer combination

95 Furthermore, their tuning functions adapt to the range of values available

96 ment as it has been demonstrated that it can tune further transformations on the NCs, leading to more

97 activity is differentially recruited to fine-tune gene expression levels in each cardiac chamber.

98 dy provided the first evidence that APP fine tunes GPCR signaling and trafficking.

99 miRNAs play an important role in fine-tuning host immune homeostasis and responses through the

100 Thus, HBL1 plays a modulatory role in fine-tuning human-specific cardiomyocyte development by formi

101 nations and doses, with implications to fine-tuned immunotherapies.

102 tion (kT1-->S0) rate constants can be finely tuned in M-(PM')n-M compounds and (ii) demonstrate desig

103 evice linear and nonlinear properties can be tuned in order to exhibit the desired behaviour at the s

104 Finally, orientation tuning in V1 was not inherited from single presynaptic L

105 he precision of interventions can be further tuned, in conjunction with the ability to establish targ

106 e create LCR mutations, which systematically tune its biophysical properties and Pab1 phase separatio

107 ty, altogether allowing the cell to robustly tune its ZDHHC6 activity.

108 ric field, selects the K-channel process and tunes its magnitude.

109 that the histidine is hydrogen-bonded to N2, tuning its reduction potential.

110 While generally suboptimal, linear tuning may facilitate transitive choices.

111 ion of mammalian cochlear physiology is that tuned mechanical vibration of the basilar membrane defin

112 that competition for CaM binding serves as a tuning mechanism: the presence of competitors shifts and

113 nding of how microtubule-associated proteins tune microtubule dynamics in trans, we have yet to under

114 onferring stability to the NEFs, helped fine-tune mitochondrial protein quality control, and regulate

115 must integrate social and hormonal signals, tune motivation, and coordinate social interactions.

116 ly localize to the AIS and are essential for tuning neuronal excitability.

117 ount correlations between pairs of similarly tuned neurons but decreased spike-count correlations bet

118 lso encoded spoken numbers, but these number-tuned neurons did not carry recognition signals.

119 Axis-tuned neurons thus provide a powerful mechanism for mapp

120 unt correlations between pairs of oppositely tuned neurons.

121 rts host protection during infection by fine-tuning NF-kappaB activity, suggesting that SP110b may se

122 tive modulators of gene expression that fine-tune numerous biological processes.

123 rials design platform allows for independent tuning of actuator rigidity and elasticity over broad ra

124 We show a strict fine-tuning of binding and sequence-dependent alterations of

125 Finally, we propose that precise fine-tuning of conduction along already-myelinated axons may

126 tween the cortical neurochemical milieu, the tuning of cortical activity, and variability in perceptu

127 specific cell populations, enabling adaptive tuning of emotional responding and behavioral flexibilit

128 This may contribute to the fine tuning of expression of the denitrification respirome an

129 y attributed to a modulation of the gain and tuning of feature-selective units in visual cortex.

130 al cavity set-up allowing for optoelectronic tuning of feedback into a quantum cascade laser.

131 presents a structural basis for evolutionary tuning of function in functionally diverse enzyme homolo

132 particular microRNAs (miRNAs), regulate fine-tuning of gene expression and can impact a wide range of

133 nction of m(6)A is post-transcriptional fine-tuning of gene expression.

134 directly controlled, thus allowing versatile tuning of geometrical frustration and manipulation of gr

135 s a handle for further functionalization and tuning of its properties, as it is shown to be susceptib

136 Proper tuning of kinetics and emission wavelengths enables the

137 imings of DNA-based data and the directional tuning of motor cortical cells during a center-out reach

138 configuration allowing efficient electrical tuning of near total optical absorption in monolayer gra

139 rted-U" input-output curve, impaired spatial tuning of neural activity and impaired sparse coding of

140 of information, and deficits in the temporal tuning of neural activity and its implication for neural

141 ription factors and coregulators in the fine tuning of organismal metabolism.HDAC3 is a critical medi

142 e, quantized activation process enables fine tuning of PANX1 channel activity and may be a generalize

143 Here, we show active tuning of quantum size effects in SP resonances supporte

144 modeling proposes that the observed spectral tuning of simple ocellar photoreceptors in the honey bee

145 nal to noise, contrast-invariant orientation tuning of single units manifests in population response

146 Achieving such easily predictable tuning of T1/2, and hence of spin-state, is a significan

147 the cochlear partition and active frequency tuning of the basilar membrane are enhanced in the cochl

148 nds of the ZnO nanowires, which leads to the tuning of the current to be transported through the syst

149 The fine-tuning of the electronic properties and redox potentials

150 s) is a key, yet underexplored, approach for tuning of the electronic properties of semiconductors.

151 se a general mechanism that enables the fine-tuning of the Fermi velocity in Dirac materials in a rea

152 he baseline activity levels and the temporal tuning of the first directionally selective neuron in th

153 able absorption characteristics, all through tuning of the heteraromatic ring.

154 etween hydrophilic and hydrophobic, but fine-tuning of the microenvironment is possible by adjusting

155 This doping process allows tuning of the plasmonic properties of a semiconductor ac

156 ly on deposition method enables not only for tuning of the spectral response of the investigated bios

157 combination of a changing E/I ratio and the tuning of total synaptic input.

158 th a cysteine-containing biomolecules can be tuned or even suppressed through the addition of at leas

159 We also looked at whether the tuning organization along these brain regions showed any

160 hose spectral performance can be dynamically tuned over a large scale remain rare.

161 ve preference between the two factors can be tuned over a wide range by changing the DNA sequence, wi

162 tput variations with parameter changes or to tune parameters.

163 iveness in high dimensions and often require tuning parameters for different domains and datasets.

164 These results suggest that the tuning parameters for direction selectivity are specifie

165 In summary, these remodeling processes tuned photosynthesis according to the demands placed on

166 ic back-up systems, are responsible for fine-tuning physiological redox signaling.

167 amined the role of serotonin on well-defined tuning properties (orientation, spatial frequency, contr

168 Still, how such different tuning properties are constructed is unclear.

169 Thus, the tuning properties of individual cells inside the visual

170 ingly offers the potential to infer neuronal tuning properties.

171 e response of many single neurons with known tuning properties.

172 The development of rapidly tuning quantum cascade lasers has increased the PTIR thr

173 Furthermore, the assay can be used for fine-tuning reaction mixtures of various agents to enhance th

174 y tuned, there is no apparent segregation of tuning responses within any discrete HsOr subfamily.

175 These data imply that contrast and size tuning result from a combination of a changing E/I ratio

176 tion, the ionic properties of the COF can be tuned reversibly, thus forming the basis of size-exclusi

177 ation of metal and oxide at the interface in tuning selectivity, and identify the key descriptors to

178 ation, as each of its components can be fine-tuned separately to increase reaction rates and/or selec

179 mational switch of aromatic side-chains fine-tunes sequence specific binding affinities.

180 nges in gene copy number (N), syntenies, and tuning sites along each phylogenetic branch during evolu

181 Evolutionary adaptation in tuning sites under different living environments was dis

182 yping, we propose target haplotypes for fine-tuning starch structure in rice through marker-assisted

183 But how local remodeling tunes stress production and dissipation, and how this in

184 correlated regime and does not require fine tuning, suggesting that this state is generic for popula

185 ontrolling FN structure and dynamics through tuning surface chemistry, we found that as the conformat

186 between pairs of LGN neurons is more tightly tuned than predictions based simply on receptive field s

187 ature evolved alternative mechanisms to fine-tune the activity of a cysteine protease dubbed RD21 (RE

188 isage that mutagenesis could be used to fine-tune the balance between the endogenous metabolic networ

189 functions in a rheostat-like manner to fine-tune the cell-type-specific transcription of genes that

190 e and the incident light intensity at 355 nm tune the characteristic switching time over several orde

191 Thus, PNUTS and PP1 together fine-tune the dynamic phosphorylation of DNA-PKcs after DNA d

192 reater target specificity and the ability to tune the dynamic range, as well as encapsulation of mult

193 which to study electrons in solution, and to tune the electron density from the extremes of electroly

194 The ability to tune the emission is attributed to electronic transition

195 se tilt patterns offers a potential means to tune the exploitable electric behaviour that arises from

196 both strains, the mutant was unable to fine-tune the expression and activity of oxidative phosphoryl

197 ity of myelination represents a mechanism to tune the flow of information by balancing functional req

198 Electrostatic fields tune the ground state of interfaces between complex oxid

199 i) can be used as a handle to systematically tune the helical pitch from 80 to 130 nm; and (ii) influ

200 aser-induced graphene (LIG), specifically to tune the hydrophobicity and hydrophilicity of the LIG su

201 dendritic block enabled us to systematically tune the hydrophobicity and stability of the assembled m

202 able and nonviable Gram-negative bacteria to tune the immune response, thereby limiting collateral da

203 appa B kinase subunit beta (IKKbeta) to fine-tune the inflammatory response to the strength of the of

204 e different from their surrounding bulk, can tune the LaAlO3/SrTiO3 interface 2DEG at the nanoscale.

205 ligomerization respectively, which we use to tune the levels of Raf/MEK/ERK signaling.

206 relation communities, we designed mutants to tune the mechanical stability of the weakest hanging coh

207 , providing new opportunities to control and tune the mechanics of layered crystals and other complex

208 ocked DNA nanostructure that is able to fine-tune the oxidative catalytic activity of a split DNAzyme

209 stem Gd0.1 Ce0.9 O2-delta /Er2 O3 to set and tune the property of "memristance." The modulation of in

210 cating that waveform symmetry can be used to tune the relative sizes of reversible and irreversible a

211 fects are due to independent mechanisms that tune the surface properties.

212 These modifications tuned the homopolymerization rate constants over 2 order

213 ctions, suggesting that local adaptation has tuned the timing of and cross-talk between fundamental p

214 and the inside-out mechanical coupling that tunes the cell internal stiffness to match that of its s

215 aL-ubiquitination-dependent switch that fine-tunes the dynamic organization and activation of the mTO

216 spontaneous polarization, which effectively tunes the electrical band bending of TiO2 .

217 ening through protease-Gag interactions fine-tunes the lifetime of the productive complex and hence t

218 terminus is essential for STIM1, as it fine-tunes the open Orai channel gating, thereby establishing

219 epends on two parameters, a coefficient that tunes the substitution matrix and the maximum length of

220 s the metabolic rate of HIV-1 replication by tuning the availability of building blocks for reverse t

221 ted growth of the supramolecular assembly by tuning the balance of attractive and repulsive intermole

222 reedom which can provide more flexibility in tuning the bandgap and also reduces the growth temperatu

223 ans to control the surface features, thereby tuning the catalytic property of the material.

224 , yellow-, and red-emitting CD aggregates by tuning the concentration of fatty acids.

225 This would allow fine-tuning the dosage according to the patient's metabolism,

226 MOF-supported single-site solid catalysts by tuning the electronic and steric properties of the SBUs.

227 y the ubiquitin ligase Neuralized, thus fine tuning the endocytosis and activity of this apical deter

228 unable across the entire visible spectrum by tuning the excitation wavelength.

229 rating plate exhibits 3 types of motion - by tuning the frequency and the amplitude of the vibration,

230 As one example, we find that by tuning the hopping parameters, it is possible to drive t

231 ing a potential antibiotic-free strategy for tuning the innate immune response to treat methicillin-r

232 Our results reveal that tuning the interface structure, distribution, and phase

233 ents one approach to address these issues by tuning the isomerization reactions of photo/thermoswitch

234 We demonstrate that by tuning the length and eluotropic strength of the pulses,

235 In particular, tuning the magnetostatic interactions in geometrically f

236 We optimized this mobile SEF system by tuning the metal-film thickness, spacer distance, excita

237 findings suggest a role for pharmaceuticals tuning the neuroimmune system as therapeutics for alcoho

238 heterodimers into Pd-Ni-P nanoparticles and tuning the Ni/Pd atomic ratio to 1:1.

239 gments at specific mutual orientations, thus tuning the overall energetic landscape and ensuring high

240 (setting vane boundaries), respectively, by tuning the periodic-branching programme of epithelial pr

241 in synthetic lipid scaffolds can be used for tuning the photoexcitation characteristics of PSI.

242 We show that local order can be modulated by tuning the potential between monodisperse, spherical col

243 Moreover, we show that tuning the range of the repulsive force below the partic

244 tional changes, is primarily accomplished by tuning the side-chain hydrophobic or ionic interactions.

245 By tuning the solution-state structure, films with high cry

246 This demonstrates a means of tuning the structures and properties of high-entropy all

247 By tuning the surface energy of the constituents, we direct

248 By tuning the temperature, vesicles can be directed towards

249 e unique to each lanthipeptide and that fine-tune their activities and/or stability.

250 However, the absence of strategies to tune their thermal half-lives by modular molecular desig

251 between these limiting behaviors by actively tuning their overall acquisition probability.

252 Tuning them properly may be difficult and, typically, ba

253 ereas individual HsOrs appear to be narrowly tuned, there is no apparent segregation of tuning respon

254 tational results suggest that the ability to tune thermal stability without affecting the dyes' absor

255 satile modification that can be used to fine-tune these cell cycle events, frequently through process

256 A user can tune these parameters to model various types of reaction

257 ammonium lead triiodide single crystals with tuned thickness of tens of micrometers are directly grow

258 monstrate that human glucocorticoid receptor tunes this signaling in vivo by producing translational

259 roperties are systematically and predictably tuned through variation of the quantum dot-molecule ener

260 Fermi level tuning through the Dirac point results in a collapse of

261 nductivity along a single Si nanowire can be tuned to a desired value (between crystalline and amorph

262 /C --> actomyosin pathways must be optimally tuned to compromise between generation of motility force

263 wn about the efficiency of UVB emitting LEDs tuned to different wavelengths for producing vitamin D3

264 train statistics of the central node can be tuned to have a certain firing rate and variability, or

265 vibratory measurements at cochlear locations tuned to high frequencies (>7 kHz).

266 at respond only to the contralateral eye are tuned to higher spatial frequencies.

267 as well as shape in the cathodes were easily tuned to improve oxygen evolution efficiency by 30% and

268 s and suggest that an adaptive magnetic map, tuned to large-scale features of ocean circulation, faci

269 account, coupling to the environment can be tuned to lower values, unlike in previous studies.

270 nomes, but their mobilization must be finely tuned to maintain host organism fitness and allow for tr

271 IPM programs are now being fine-tuned to meet regulatory and market standards.

272 re the geometry of the metadiffuser has been tuned to obtain surfaces with spatially dependent reflec

273 example, TCs are more sensitive and broadly tuned to odors than MCs and also are much more sensitive

274 ze, suggesting total synaptic conductance is tuned to postsynaptic excitability.

275 y and transcription factor levels are finely tuned to regulate stochastic expression, setting the rat

276 r is retained upon myristoylation and can be tuned to span a 30-60 degrees C.

277 ion and interactions with other channels are tuned to species-specific requirements.

278 ternal excitation, enabling the system to be tuned to the desired load and to clear the working memor

279 inating reproduction and typically have ears tuned to the dominant frequency of their vocalizations,

280 ckward-propagating attenuation of units less tuned to the target.SIGNIFICANCE STATEMENT Whether searc

281 iption of the Al-Si-Fe-Cu system needs finer tuning to accurately predict the stability of the omega-

282 calization cues are integrated: cortical ILD tuning to broadband sounds is a composite of separate, f

283 ren as young as 3-4 years old exhibit neural tuning to cardinal numerosities in the IPS and that thei

284 ing hierarchy in the brain: mirror-symmetric tuning to head orientation [7].

285 neural activity that do not represent neural tuning to numerosity.

286 These included, in particular, tuning to only a small number of facial features that we

287 ve-field properties, they also have distinct tuning to the size, speed, and type of motion on the ret

288 latory elements in specific settings to fine-tune transcriptional regulation in response to environme

289 terically control function by simultaneously tuning transcriptional activation and repression, using

290 whose mutual interaction can be effectively tuned using an external laser driving a quasi-resonant R

291 nge positional order whose properties can be tuned using the isoreticular chemistry approach.

292 material's properties, many of which can be tuned via chemistry.

293 equencies (<2 kHz) and found that mechanical tuning was broad and did not match auditory nerve tuning

294 Through systematic structural parameter tuning, we realize an efficient balance between confinem

295 As a result, the bandgap can be tuned which varies from 1.61 to 1.85 eV.

296 are associated with more selective cortical tuning, which in turn is associated with enhanced percep

297 the ability to make inferences about neural tuning width from inverted encoding models.

298 force (from 23 muN to 55 muN) can be easily tuned with different number of eggbeater arms for potent

299 solder), mechanical rigidity can be actively tuned with external heating or electrical activation.

300 Tuning YAP transcriptional activity leads to the modific