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1 dual valleys and derived the LL structure in turn.
2 ting of mixtures of type II and type IV beta-turns.
3 ype at the start and end of tethered-walking turns.
4 which are highly reminiscent of peptide beta-turns.
5 l-beta-sheets (1690cm(-1)) and H-bonded beta-turns (1664cm(-1)).
6 e outcome of chronic myeloid leukemia (CML), turning a life-threatening disease into a chronic illnes
7 aph-based clustering algorithm, our approach turns a whole genome assembly problem into a set of inde
8  the nuclear factor-kappaB pathway, which in turn accentuates the priming of Nlrp3, promotes Nlrp3-AS
9 sing their porosity or crystallinity, and in turn achieving designed properties in materials.
10 r pathways used by DCs to sense alum and, in turn, activate T and B cells.
11                                Tfap2alpha in turn activates multiple genes including the protocadheri
12 6 (cluster of differentiation 36), which, in turn, activates a Nox2-containing NADPH oxidase, leading
13                                           In turn, activation of SMO induces FU to act on its downstr
14 iratory to photosynthetic carbon flux and in turn adjusts stomatal conductance, photosynthetic CO2 an
15 phenotypes and social interactions, which in turn affect key evolutionary processes such as sexual se
16 t regulatory influence over RAD51 and may in turn affect the properties of the assembled RAD51 filame
17 ts within the organic semiconductor, and, in turn, affect the electronic properties of the material.
18 d tool morphology, and that hook geometry in turn affected crows' foraging efficiency.
19 -righting, the capacity of an animal to self-turn after falling on its back, is a fitness-related tra
20 s with high risks of breast cancer, which in turn aids in the individualization of treatment.
21  this microbial "dark matter," which will in turn allow detailed mechanistic studies of the effects o
22                                      This in turn allowed mutational redesign of disassembly and test
23 NsrR structure suggests that Asn97 from this turn, along with Arg12, which forms a salt-bridge with A
24                                     These in turn alter the predicted mechanical response of the myos
25 on of skin lipids and proteins, which may in turn alter the protective skin barrier function.
26                                           In turn, alterations found in RDEB skin cell behavior foste
27  editing-dependent stabilization of mRNAs in turn alters the observed editing levels in the stable RN
28                                           In turn, AMPK activates FOXO3A and its transcriptional targ
29 sampling results for 35 RNAs, including 12 k-turn and 23 non k-turn internal loops, and compare the r
30 Abeta adopts unfolded structure dominated by turn and random coil conformations.
31 bone forms transient, sparse hydrogen-bonded turns and remains significantly hydrated even as self-as
32                                           In turn, ann1 mutants showed elevated chitin-induced rapid
33  MOG are both presented to T cells, which in turn are activated and proliferate.
34 ions, and congenital malformations, which in turn are associated with increased risks of cerebral pal
35                            Dopamine cells in turn are innervated and regulated by neighboring inhibit
36 ar H(+)-pumps, SlAVP1 and SlVHA-A1, which in turn are revealed as potential targets of SlCBL10.
37 nd in both RASopathies and cancer, which, in turn, are generally more severe than those found only in
38 al influence and persuasion on receivers, in turn, arise from changes in the receiver's subjective va
39                                          The turn-around time for a typical efficacy study using micr
40 he glassy carbon would be hydrated, which in turn assist to adsorb the uranyl sulfates through hydrog
41  stronger left amygdala connectivity were in turn associated with lower impulse control at 24 months
42 duced levels of physical activity, which, in turn, associates with the development of numerous chroni
43 s light on how superfamily 1 and 2 helicases turn ATP hydrolysis into motion along DNA.
44                   T1 relaxation times can in turn be used to calculate the concentration of a gadolin
45 ey operate close to budgetary boundaries, in turn because they consistently operate with limited budg
46 ar to error-related negativity, which has in turn been implicated in general performance monitoring.
47 e (MLCK) were responsible for the intriguing turning behavior of T cells climbing the ramp-like struc
48 s elegans larvae, sleep is associated with a turning behavior, called flipping, in which animals rota
49 shows that the [4Fe-4S] cluster stabilizes a turn between ScNsrR Cys93 and Cys99 properly oriented to
50                                           In turn, biocrust community shifts affect land surface cove
51 bsorbed into mainstream biological training, turning biology into a quantitative science.
52 among the four kinds of samples, followed in turn by the Al-TiO2 nanoparticles prepared with AlCl3, A
53                                           In turn, by gaining better insight into the drivers of popu
54            Five of 8 C4d-positive recipients turned C4d-negative in 5-week follow-up biopsies, while
55 regulated in injured motor neurons, which in turn can activate astrocytes through ephrin-B1-mediated
56 o affect immune system development, which in turn can affect brain development and its long-term func
57 al type mediates nutrient dynamics, which in turn can influence forest community structure and proces
58 and entrain brain networks, and that this in turn can modify behaviour.
59 hen combined with further processes which in turn can provide potential benefits in the recovery of v
60 ng adducts in good to high yields, which, in turn, can be easily converted into a wide array of enant
61 cells ('losers') but why some gene mutations turn cells into losers is unclear.
62 t outcomes by increasing the total time with turning compliance and preventing pressure injuries in a
63 biology of glycan-binding proteins, which in turn complicates the biomedical use of this class of bio
64 n and induced Stc2 gene expression, which in turn confers cytoprotection to liver cells exposed to ch
65 igned to mimic the suggested bioactive gamma-turn conformation of the Bip-Lys-Tyr tripeptide in Uroco
66 sharing behavior, where each community takes turns consuming nutrients.
67 roliferation and angiogenesis, which may, in turn, contribute to positive PET/CT and CT performances.
68 ynaptic strength in VTA DA neurons, which in turn contributes to PE-induced increase in addiction ris
69 that can result from these adductions are in turn correlated with specific cancers.
70 roteases may enhance NanI activity, which in turn could further potentiate the activity of intestinal
71 ellitus and cardiovascular disease, which in turn could lead to reduced risk of downstream cardiovasc
72 es that bolster AM fungal communities may in turn create systems that are more resilient to these cha
73  of p14ARF, activates MDM2 protein, which in turn degrades TP53 tumor suppressor.
74 pression of ETH and ETH receptor genes is in turn dependent on ecdysone (20E).
75 ted by the lighting environment, which is in turn dependent upon habitat [1, 3, 5, 6].
76 st P. aeruginosa biofilm formation, which in turn depends on the presence or absence of FBS.
77 hysically meaningful parameters and which in turn determine bias and variability of the m/z measureme
78 on depends on genetic architecture, which in turn determines responses to natural selection.
79 r HIV-1 replication and infectivity-which in turn detrimentally affects proviral transcription and vi
80                                    USP13, in turn, deubiquitinates RAP80 and promotes RAP80 recruitme
81                                           In turn, diffusion anisotropy changes were strongly associa
82                                      This in turn diminished the embryonic origin of postnatal NSCs,
83 15(INK4B) through promoter demethylation; in turn, DNMT1 dysfunction impairs KIT kinase signaling.
84 in steep differentials in survival, which in turn drive hybrid zone movement for two woodrat species
85                                      This in turn enables EigenTHREADER to correctly identify analogo
86                                      This in turn enables precise in-situ alignment detection, for th
87 me-associated protein 23 (SNAP-23), which in turn enables the formation of the SNARE complex to allow
88 cterial overgrowth of enterococci, which, in turn, exacerbate ethanol-induced liver disease both in m
89 type, including direct activation of Ccr2 In turn, expression of ZEB1 by TAMs induced Ccl2, Cd74, and
90                                      This in turn facilitates CENP-A(Cse4) nucleosome deposition and
91 nts enhance growth factor production that in turn facilitates hair follicle development and cycling.
92  because it binds Gas6 more avidly, which in turn facilitates its interaction with AXL.
93                              MacroH2A1.2, in turn, facilitates the accumulation of the tumor suppress
94                                      This in turn forces a re-evaluation of its demography and extinc
95  well as unlabeled axon terminals, which, in turn, form inhibitory-like synapses on auditory efferent
96 ts due to their molecular switch function in turning gene expression on or off and scaffold-like prop
97                      The results showed that turned green and also sprouting or rotting potato flesh
98 ne addition has proven challenging, which in turn has limited the capabilities of the RNP-mediated ge
99 eased reliance on genetic testing, which, in turn, has raised new diagnostic challenges.
100 s of a tetratricopeptide-repeat (TPR), helix-turn-helix (HH), and U-box domain.
101                        TFs with winged helix-turn-helix (wHTH) motifs use an alpha helix to read the
102 main, a helical hairpin, and bipartite helix-turn-helix motif.
103  protein, Gp5.7, which adopts a winged helix-turn-helix-like structure and specifically represses tra
104              This across-saccade process, in turn, helped to set the starting point of the next withi
105 ntial nutrients to the photoreceptors and in turn helps patients maintain better than expected visual
106 phosphate) oxidase-dependent killing and, in turn, host susceptibility to invasive aspergillosis.
107 tic variant calling methodologies, which, in turn, impacted associations with clinical outcomes.
108  provokes the release of serotonin, which in turn impacts on the serotonin 1A receptor system, by mod
109 mage and cellular energy deficits; these, in turn, impair mitophagy.
110 ned endogenous alpha-band networks, which in turn impaired task performance.
111 netically regulated accretion mode, which in turn implies the existence of magnetically gated accreti
112                                      This in turn improved dough handling, bread crumb texture and cr
113 e population correlation structure, which in turn improves population-coding abilities.
114 kdown reduced axon outgrowth and growth cone turning in Wnt5a gradients, likely due to disorganized M
115 ensity activates the Hippo pathway, which in turn inactivates YAP, leading to changes in the regulati
116                                           In turn, increased ferritin protein levels promote the expr
117 epigenetic reactivation of ERalpha, which in turn increases TAM-dependent anti-estrogen chemosensitiv
118                                           In turn, increasing enzyme activities promoted ecosystem re
119 ling via the binding of ENb to EGFR which in turn induces DR5 clustering at the plasma membrane and t
120 influence experimental efforts, which may in turn influence the outcome of cellular differentiation.
121 ound alterations in gene expression that, in turn, influence tissue homeostasis, tumorigenesis, and c
122 h SUMO-specific protease 1 (SENP1), which in turn inhibits SENP1-mediated de-SUMOylation of Rac1 to a
123 ead diphosphine ((CH2)14)3 P (1) can rapidly turn inside-out (homeomorphic isomerization) to give a m
124 or 35 RNAs, including 12 k-turn and 23 non k-turn internal loops, and compare the results to solved s
125 Finally, strategies used by informed players turn into non-stationary processes in which the length o
126                               The precursors turn into self-assembling molecules to form nanofibrils
127 the neuroimmune system in psychiatry may not turn into therapeutic hope for affected individuals.
128 crete neurotoxic damages, TSPO has generally turned into a biomarker of 'neuroinflammation' or 'micro
129 expansion of the cloud, as if the system has turned into a diffusive collision-full classical system.
130                         The prepolymers were turned into thermoresponsive polymers by thiol-ene modif
131 timulus that initially interests a fruit fly turns into a familiar one.
132 acts, this six-residue sequence element also turns into a well-defined structural element upon fibril
133 ide to release daughter merozoites, which in turn invade new erythrocytes perpetuating the cycle resp
134 ith more selective cortical tuning, which in turn is associated with enhanced perception.
135 ed by the metalloprotease ADAMTS13, which in turn is conformationally activated by VWF.
136 ts own specific substrate gradient, which in turn is produced by the preceding enzymatic reaction.
137                     Under this guidance law, turning is commanded at a rate proportional to the angul
138 emonstrate that regulated SRF expression, in turn, is critical for the effects of cocaine on dendriti
139 eir hair bundles drive the cell body and, in turn, it has been assumed, amplifies the signal.
140 using beyond issues of internal validity and turning its attention to questions of external validity.
141 ral pro-inflammatory cytokine production, in turn leading to depression and cognitive deficits.
142 compromises the LKB1/AMPK signaling axis, in turn leading to the elevation of NSCLC cell proliferatio
143 ne metabolic genes to increase SAM, which in turn leads to an increase in global H3K4me3.
144  ratio between these subpopulations; this in turn leads to distinct infection outcomes in vitro and i
145 ognition of target dsDNA (dsDNA-T), which in turn leads to the formation of a high density of PNA/DNA
146 and visiting less-productive waters; this in turn led to differences in flight activity and energy ex
147 n to diphenyl sulfide radical cation that in turn led to diphenyl sulfoxide.
148          The increased cytosolic calcium, in turn, led to the phosphorylation of calcium/calmodulin-d
149                                           In turn, longer migration correlates with lower reproductiv
150                                              Turning magnitude (21 degrees , p=0.923) and adequate de
151 haviors of cancer cells as a population - in turn may become a determinant of cancer progression pote
152 at creates large coherency strains, which in turn may promote crack initiation under load.
153                                     This, in turn, may affect zoospore transmission.IMPORTANCECucumbe
154 rizzled and Wnt-SFRP interactions, which, in turn, may reveal further Wnt signaling pathways.
155                                      This in turn means that the formation of majority legislative co
156 ET-B receptor in endothelial cells, which in turn mediates the decrease in extracellular ET-1 concent
157                                           In turn, mevalonate created a positive feed-forward loop to
158 Effectively synthesized, benzotriaepin-2-one turn mimics offer the potential to differentiate the res
159    Genetic deletion of CTGF from neurons, in turn, mitigates the TSC-dependent hypomyelination phenot
160 ting mothers eat flavors breast milk and, in turn, modifies their infants' acceptance of similarly fl
161 operties such as fluidity and charge that in turn modulate interactions with membrane-associated prot
162 gly confined chemical reactions that can, in turn, modulate the tunnelling processes.
163                 Here, we annotate observed k-turn motifs within a non-redundant RNA dataset based on
164 nowledge-based potentials with and without k-turn motifs.
165 erentially active in the germline, which, in turn, mounts defenses that restrain their activity [3, 4
166 the paxillin-rich adhesion plaques, which in turn move more quickly than the local matrix, an observa
167                         When placed into the turn of a beta-sheet, this leads to a pH switch of foldi
168 TNF) secretion, which leads to activation in turn of c-Jun N-terminal kinase (JNK), the Axl receptor
169  that was deemed unattainable by some at the turn of the 21st century.
170                           The d-Phe-Pro beta-turn of the cyclic beta-hairpin antimicrobial decapeptid
171 burden of atrial fibrillation (AF) since the turn of the millennium.
172 ormation in a T11-tract that covers one full turn of the nucleosome helix at seven different SHLs, an
173  the extended Omega-loop, and a beta-hairpin turn of the Phy-specific domain.
174 titutive Shisa2 expression causes randomized turning of post-crossing commissural axons along the ant
175 g reactions if within one and a half helical turns of superhelix location 2 (SHL2), where the Chd1 AT
176 ur locations distributed over the apical two turns of the guinea pig cochlea.
177          Ethers and chloride salts dampen or turn off reactivity, leading to three distinct catalyst
178  0.001 to 100000ng/mL (R(2) = 0.9339) by the turn off-turn on principle.
179                             The surge can be turned off by fixing the rate of fluid flow through the
180                           When the light was turned off motoneuron firing and locomotor frequency bot
181 o turn on anion transport, which can then be turned off through addition of the blocker dodecyl sulfa
182 osphorylation-sensitive molecular switch for turning off or on RP mRNA translation and subsequent rib
183 -metal interactions lead to both turn-on and turn-off fluorescence sensing mechanisms, enhancing the
184 it displays a ratiometric response, while a "turn-off" sensing is observed specifically in the presen
185 iomarkers be nonexistent, the signal remains turned-off.
186  may represent a cis-regulatory mechanism to turn on a group of genes that are commonly and restricti
187 15 prism thus inserts into lipid bilayers to turn on anion transport, which can then be turned off th
188  100000ng/mL (R(2) = 0.9339) by the turn off-turn on principle.
189 tinuously, by running a program for 17h that turned on an LED every 60s.
190                               Each switch is turned on and off sequentially to distribute and route t
191 d host-guest-metal interactions lead to both turn-on and turn-off fluorescence sensing mechanisms, en
192 dual probe for colorimetric and fluorescence turn-on assays of spermine and spermidine in biological
193 novative method for a universal fluorescence turn-on enzyme assay, which relies on the target enzyme-
194                  CO release is chaperoned by turn-on fluorescence and can be triggered by light (405
195 th tunable reaction rates, high fluorescence turn-on ratio, and easy access.
196 a green fluorescence protein (GFP)-mimicking turn-on RNA aptamer, Broccoli, into two split fragments
197                                         The "turn-on" fluorescence property of the chemosensor makes
198 tial genes identified by genetic screens may turn out to be components of selfish elements.
199 othiazol-2-yl)-4-propoxybenzamide (3), which turned out to be an analog of the drug nitazoxanide (1).
200 uated in combination with flow cytometry and turned out to be around 25% (cells entering the ICP-MS f
201                 The temporal order of spikes turned out to be crucial.
202 ns used in nanomedicine and nanoformulations turned out to be inapplicable to clinical applications.
203  with XO entrapped Ta2O5 nanofibers has been turned out to possess maximum sensitivity amongst the sy
204                         The third uridine is turned outwards or inward, wedging between the other uri
205 for the organs they encase, epithelial cells turn over at some of the fastest rates in the body.
206    Neurons can last a lifetime, but proteins turn over rapidly.
207 re networks of actin filaments generated and turned over by filament branching through the Arp2/3 com
208 mal Pex15, exaggerated by overexpression, is turned over by Msp1.
209             These substrates are efficiently turned over by the human exo-glycosidase O-GlcNAcase (OG
210 amine signaling in pyramidal neurons that in turn pathologically recruits l-type Ca(2+) channels to f
211 aspects, and their discovery is considered a turning point in human history.
212 or cochlear amplification in the stiff basal turn, possibly through maintaining cochlear partition me
213 ures and to RAGTOP results without special k-turn potentials.
214  and highlight the need to reinforce optimal turning practices.
215 modified CA1 codes during learning, which in turn predicted how quickly rats adapted to subsequent ru
216 o abnormal repolarization in HFpEF, which in turn predisposes to VA and sudden cardiac death.
217 c eruptions produce sulfur dioxide, which in turn produces aerosols; these eruptions thus represent a
218                                       DDi in turn projects strongly to DDmg, which then feeds back di
219 imarily to perirhinal cortex (PRC), which in turn projects to lateral entorhinal cortex (LEC).
220 of the CXCL13 by TME stromal cells, which in turn promoted ILC3-stromal interactions and production o
221 hs at the apical junctional region, which in turn promotes growth by inhibiting Warts.
222 lts in bottom water oxygen deficiency and in turn promotes sediment phosphorus (P) release (A).
223 d NBs permits Prospero accumulation that, in turn, promotes cell cycle exit.
224 ear factor kappa-B ligand (RANKL), which, in turn, promotes the periodontal bone loss via upregulatio
225 for further experimental work, which will in turn provide input to refine and develop the model.
226 e mechanism for followers, follower cells in turn provide leaders with increased growth and survival.
227 O to create more active edge sites, which in turn provides a strong evidence for the theoretical indi
228 e show that PTEN interacts with DAXX and, in turn PTEN directly regulates oncogene expression by modu
229                                           In turn, pyramidal cell targets of SST(+) neurons showed an
230     These are the first quantitative data on turn quality in the Intensive Care Unit and highlight th
231                                These ChCs in turn receive preferential input from local and contralat
232 e production of the chemokine CCL2, which in turn recruited circulating CCR2(+) monocytes toward infe
233 e-unoccupied molecular orbital (SUMO), which turns rectification off and drops R to 6.
234  PG activity in Arabidopsis leaves, which in turn reduces leaf pectin content and leaf robustness.
235                    Circulating AKH levels in turn regulate lipid homeostasis in fat body/adipose and
236 ggered downstream regulatory genes, which in turn, regulated downstream metabolic pathway genes to bi
237 with the Ptpn11 (Shp2) phosphatase, which in turn regulates ShcD tyrosine phosphorylation.
238 t control of c-MYC (MYC) expression that, in turn, regulates expression of the glycolytic enzyme hexo
239             M6CK histone phosphorylation, in turn, regulates transcription by attenuating the effect
240              These patterns and practices in turn reinforce discriminatory beliefs, values, and distr
241 tudinal and lateral displacements of helical turns related to constriction.
242              These decision-making needs, in turn, require mission-oriented basic science, for exampl
243 orum revealed the presence of a central beta-turn resembling that of its yeast counterpart.
244 ed ferroportin 1 (FPN1) expression, which in turn results in decreased cellular iron export.
245  the MYC transcription factor NME2, which in turn results in down-regulation of MYC transcription.
246 quent abortion of septum synthesis, which in turn results in the production of long spore-like compar
247  the axial dimension of the volume which, in turn, results in distorted image volumes.
248 bilize with appropriate dispersion, which in turn severely limits their catalytic functions.
249  production and dissipation, and how this in turn shapes long range flow, remains poorly understood.
250 ns stabilize the amyloid structure, which in turn shapes the ligand geometry and catalytic reactivity
251                    Outcome from nonshockable-turned-shockable OHCA is poor but not invariably fatal.
252 ial VF/VT and 1063 with initial nonshockable-turned-shockable rhythms were treatment-eligible, were r
253 s interfere with signaling dynamics, and, in turn, signaling dynamics affects inhibitor responses, we
254 o distinct mineral assemblages, which are in turn stabilized by biophysical feedback mechanisms actin
255 lia in the MBH hypersecrete TNFalpha that in turn stimulate mitochondrial ATP production in POMC neur
256                                      This in turn stimulates production of type III interferons and h
257                 Resource availability is, in turn, strongly dependent on plant patterning mediated by
258 tective tolerance induced by Indacaterol, in turn suggesting that cross-talk may not be clinically re
259                                           In turn, suppressed abundances of rodents and rabbits in th
260                    We also show that Plk3 in turn suppresses the SIAH2 protein level in a kinase acti
261  of membrane-bound glycolytic enzymes and in turn switches glucose flux towards glycolysis relative t
262   Elevated bile acids activate FXR, which in turn switches off bile acid synthesis by reducing the mR
263 ies changes the linker flexibility, which in turn switches the breathing behavior of 2.
264  cell body volume, respectively, but that in turn the compactness of heterochromatin was not a limiti
265  to the regulation of photosynthesis, and in turn the daily accumulation of sugars from photosynthesi
266 s were resolved upon metalation, effectively turning the charge state and cationization mode into ext
267  phase represents an elite strategy for fine turning the electronic structure of the catalytic center
268  and its incorporation into plankton and, in turn, the atoll corals.
269                                     In their turn, the modifications have resulted in new mechanisms
270                                           In turn, the resulting cyclic ketimine products react smoot
271                                           In turn, there is great potential for using the outputs of
272                                           In turn, this change in mitochondrial membrane composition
273                                           In turn, this impaired SUFU-mediated repression of the SHH
274                                           In turn, this suppressed tumor cell proliferation but incre
275                                           In turn, this trait, together with individual's exploratory
276  experience the least confinement, and hence turn three-dimensional tracking into a one-dimensional p
277 A) expression profile of the host, which, in turn, through regulation of the host inflammatory respon
278 nd by less-experienced operators, leading in turn to an acute need for novel test evaluation.
279 s graduate, funding ceases, or investigators turn to other projects.
280 ome (a term coined in 2001), attention would turn to the role of antibiotics and the intestinal micro
281 tissue expression profile, we have therefore turned to PAR4 as an antiplatelet target.
282 east part of the explanation may be found by turning to social relationships that arise in religious
283              Here we document a bias in head-turning to the right in adult humans, as tested in the a
284             During catalysis, C3 and C2 take turns to incorporate the two biosynthetic precursors int
285                       We examined fetal head turns to visually presented upright and inverted face-li
286 urface area of these small devices leads, in turn, to low faradaic currents and poor signal-to-noise
287    Furthermore, increased focus has recently turned toward modifiable aspects of the environment, inc
288  to deactivation of the NFkappaB pathway, in turn triggering an anti-angiogenic cascade, might inhibi
289 ins neddylation and inactivates CRLs and, in turn, triggers cell-cycle arrest, apoptosis, senescence
290  rather than cultural-societal norms, was in turn uniquely associated with greater racism, sexism, we
291 y of the larva to correct its orientation if turned upside down (self-righting, SR), suggesting that
292 proteins and protein complexes, which are in turn used as restraints for modeling the structures of t
293 s attracted a lot of attention, promising to turn vast amounts of data into useful predictions and in
294 strate that a fast life-history strategy, in turn, was associated with dysregulated weight-management
295 ngly, being connected to other people who in turn were reciprocally close to each other was associate
296  we term an "eta-helix" due to its repeating turns, which are highly reminiscent of peptide beta-turn
297 ns induce backward walking via MDNs and that turning while walking backward might reflect asymmetric
298 lations and management strategies, which, in turn, will pay dividends for both the consumers and prod
299 and carbon cycling, land productivity and in turn, worldwide socio-economic conditions.
300 s responsible for the activity, which can in turn yield simplified hERG toxicophores.

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