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1 (OCP) to measure enzyme turnover kinetics, k(turn).
2 t with the model 7/2 helix (3.5 residues per turn).
3 particularly contents of beta-sheet and beta-turn.
4 the increase in beta-sheets, and the loss in turns.
5 height and dune formation time, which are in turn a function of the rate of sea level rise, sand avai
6 ical sugar metabolism by only three enzymes, turning a non-methylotrophic organism to a synthetic met
7 nsparency and support of reproducibility; in turn, a workflow's reproducibility can be greatly affect
9 r SQSTM1 binds to insulin receptor, which in turn activates a nuclear factor kappa B-dependent metabo
10 can identify hidden fitness trade-offs that turn adaptation into maladaptation, resulting in evoluti
11 operties and irrigation management, which in turn affect genotypic rankings of transpiration in a tim
14 very strong interaction with C(60), which in turn also induces a large structural change on the other
15 valent configurations at metaphase I, and in turn alter allelic segregation ratios through double red
16 e, C(H)2 helical segments, beta-sheets, beta-turns, and random coil regions were less stable than in
18 , a series of key technological improvements turned atomic force microscopy (AFM) into a nanoscopic l
19 oxisomes that shift the current paradigm and turn attention to the reductive evolution of peroxisomes
20 h growth cones forward and prevent them from turning back once they became sensitized to these cues a
21 new task to demonstrate impairments in cued turning behavior in rodents modeling the cholinergic-dop
25 d Trp is used to engage the Pro in NPNA beta-turns, but here the Trp interacts with the first Asn.
29 l and peripheral circadian rhythms, which in turn can prevent or even treat the metabolic syndrome an
33 t striatal regions induces either licking or turning, consistent with their respective anatomical tar
34 presented here validates our model, which in turn, constitutes the first proposed systemic mechanism
35 ult in mPFC transcriptomal changes, which in turn contribute to disease conditions associated with th
36 n of hippocampal brain development, which in turn contributes to perturbed emotion regulation and sub
37 transcription status of the genome, which in turn controls nucleocapsid interaction with the envelope
39 alysis of their conformations suggested that turns corresponded to half of the total population of st
41 aptic AMPAR transport and delivery, which in turn could be critical for coupling the metabolic demand
42 s correlated with task engagement, which, in turn, could be regulated by chemogenetic excitation and
45 pre-existing low-level cloudiness, which in turn decreases downwelling infrared flux and accelerates
46 sts, even down to the strain level, which in turn defend themselves using an array of mechanisms.
48 s between geomorphology and ecology that, in turn, define spatially explicit patterns in community as
51 modulates interchromophoric interactions, in turn determining excitonic behavior and migration dynami
54 ssor Kruppel-like factor 3 (KLF3), which, in turn, directly repressed the expression of the NF-kappaB
58 to a wave of muscle contractions that are in turn due to a wave of electrical activity initiated at t
60 lpha-synuclein activates microglia, which in turn engulf alpha-synuclein into autophagosomes for degr
61 mitant release of lysophospholipids which in turn enhance expression of flagellin by Salmonella there
65 erial resulted in porous structure, which in turn ensured prolonged contact time of contaminated wate
66 hese MGEs, including bacteriophages, have in turn evolved different strategies to evade these hurdles
67 cells, that is, in a primed/prolytic state, turn expression of the replication/lytic/reactivation sw
68 romotes CAF migration and invasion, which in turn facilitates the movement of tumor epithelial cells
69 r the state of the environment, which may in turn feedback to change the incentive structure of strat
71 ecruitment of the cohesin complex, which, in turn, form chromatin loops that promote proximal polyade
73 tric SrTiO(3) via flexoelectricity, which in turn generates non-destructive, strong electrostatic fie
75 s complexity, are fueled by the data and, in turn, guide directions for future experimental and compu
76 urces of safe drinking water, which could in turn hamper efforts in China and other LMICs toward univ
77 idely different radiosensitivities, which in turn has hampered the identification of genetic elements
78 acid to epoxyeicosatrienoic acids, which, in turn, have been implicated in mediating several cardiova
81 a previously-unseen compact fold, the helix-turn-helix conformation of pUL51 resembles the cellular
84 in clinical populations to improve locomotor turning; however, the adaptive mechanisms involved are p
86 how it is affected by aging and how this in turn impacts cell function remains largely unexplored.
90 sm where the polypeptide chain does an about turn in order to enter a neighboring subunit, only for s
93 e in the density of the glycocalyx, which in turn increases the tension of the cell membrane, alters
94 dual solutions to shared problems, which, in turn, increases cooperation and decreases inequality, pa
95 he secretion of type I interferons, which in turn induce the expression of hundreds of antiviral gene
96 ssor of key regulators of the cell cycle, in turn influencing contact inhibition and tumorigenesis.
98 tantia nigra pars reticulata (SNr), which in turn inhibits nigra pars compacta (SNc) DAergic neurons.
99 tion of TPPP1 by EBV-miRNA-BART12, which, in turn, inhibits the acetylation of alpha-tubulin, and pro
101 or its hydrocarbon production and ability to turn into a selective catalyst for methanol synthesis in
102 e biological fibrils with invertase activity turn into microstructured catalysts according to electro
105 imes of metal-based anti-cancer drugs can be turned into an advantage for direct injections into tumo
107 l mice being genetically identical, which in turn is dependent on the breeding designs of companies t
108 ose tissue sympathetic innervation, which in turn is necessary to correct the associated functional d
109 increasing oxidative stress status, which in turn is proposed as a primary culprit in AD pathogenesis
111 carriage in hospitalized patients, which, in turn, is a risk factor for invasive infection in immunoc
115 We developed the algorithm STing to provide turn-key solutions for molecular typing and gene detecti
117 self-harm among asylum seekers, which may in turn lead to effective self-harm prevention strategies.
120 , the disruption of endosymbiosis), which in turn leads to coral death and the degradation of marine
121 m disrupts neuronal individuality, which, in turn, leads to a change in neural circuit connectivity a
122 r Cas2 binding over tetramerization; this in turn led to preferred integration of single spacers over
124 n the other hand, integrating Co, Mn, and Zn turns Li(2) S into a prelithiation agent, forming metal
125 er by-a continuous scaffold strand, which in turn limits the modularity and function of the DNA-origa
127 ing by mutating a TF binding motif, which in turn may affect the activity of the regulatory elements.
128 ative database for GCIPL thickness, which in turn may improve the detection and diagnosis of glaucoma
132 mples where site-specific DNA methylation in turn mediates gene expression, including FCRL3 in both c
133 causes intracellular ionic imbalance, and in turn, membrane swelling that potentially leads to cortic
134 lters the gut microbiota composition, and in turn, microbiota dysbiosis has a substantial impact on s
135 terrestrial P input into the ocean, which in turn might have impacted the marine primary productivity
136 documented spread of the HIV types, which in turn, mirrors within-China population migration flows to
139 e of sensory mediators such as ATP, which in turn modulates afferent nerve activity in response to bl
140 to the host framework S(2-) anions, which in turn modulates the Li(+) ion potential energy surface, i
141 colorectal cancer screening, which could, in turn, motivate their patients to undergo screening.
144 nitial state, RG binds to DNA and unwinds ~2 turns of the double helix in an ATP-independent fashion.
145 ecent drought of 2000 to 2010, known as the "turn-of-the-century drought," was likely more severe tha
149 vary: some centers continue CRT while others turn off the left ventricular (LV) lead at LVAD implant.
151 e of RhoA activation is insensitive to rapid turning off of the receptor and is required for maintain
152 over time causes autophagy deficiency, which turns off Nrf2-mediated defense while switching on an Nr
153 o test the efficacy of the dyes as probes, a turn-off fluoride ion probe was prepared from 3C, which
154 m affords greater than 100-fold fluorescence turn on in buffer, is selective for glucose in the prese
155 Additionally, a food signal is required to turn on TRA-1 expression in the intestine, and environme
158 s leaks and incomplete combustion while off, turning on or off, and in steady-state operation from 35
163 have developed a small molecule fluorescent turn-on probe for labeling sphingosine in living cells.
165 atinine produced supramolecular fluorescence turn-on sensors that work at micromolar analyte concentr
168 this work, we report the first luminescence "turn-on" sensors for Gsp using near-infrared emitting la
174 esponses, when compared against logic, often turn out to be rationally justified when seen in the ric
177 olypeptide appears to be highly flexible and turned out to be essential for proper functioning of Fts
178 Despite the structural simplicity, the probe turned out to be unprecedentedly highly sensitive to eve
185 rt that the NADH-oxidizing N-module of CI is turned over at a higher rate and largely independently o
187 SO(2) by NO(2), producing HONO which can in turn oxidize SO(2) to yield N(2)O.This mechanism could p
188 ersonalization and distorted social cues, in turn, pave the way for manipulation and the spread of fa
190 ed transient activation of VEGFR2, which, in turn, phosphorylated PERK at Thr(980) Subsequently, PERK
191 activates its second kinase-domain, which in turn phosphorylates sarcoplasmic/endoplasmic reticulum c
194 rests in the Mid Devonian (393-383 Ma) was a turning point in Earth history, marking permanent change
195 e English and French Revolutions represent a turning point in history, marking the beginning of the m
196 rical-poling-triggered ion migration and, in turn, polarization potential as well as into the implica
198 AUD, and the severity of this disruption in turn predicted greater heavy drinking during early treat
203 mobility of the SO(4) tetrahedra, which, in turn, provide facile pathways for proton locomotion.
205 ce until 18 months, but increased open field turn rate (reflecting hyperkinesia) and open field anxie
209 oplasmic reticulum Ca(2+) release, which, in turn, reduces diastolic cytosolic Ca(2+), leading to alt
213 le regulatory molecules, including MAPKs, in turn regulated by multiple phosphorylation cascades.
214 ducible factor-dependent signaling, which in turn regulates metabolic reprogramming, immune suppressi
218 ing SG contact the nascent PR axon, which in turn release FGF to induce SGs' differentiation into WG.
219 degrades the transcript of TRAILR4, which in turn represses TRAILR4 expression and inhibits the aggre
220 -assemble into glycodendrimersomes, which in turn resemble the surface of a cell by encoding carbohyd
221 Development of analogs to reinforce the beta-turn resulted in our first antagonist with subnanomolar
222 tophagy flux by upregulating PELI1, which in turn, resulted in degradation of LAMP2 in activated micr
223 verexpression inhibited Dicer expression, in turn, resulted in inhibition of miR-16 maturation, leadi
224 increasingly complex computational tools, in turn resulting in a steep entrance barrier for labs who
225 and suppressors of trh expression, which in turn results in a difference between the thoracic and ab
226 in the terminal psi angles of the NPNA beta-turns results in different dispositions of the subsequen
227 ns of CEP164 modulate its function, which in turn seems relevant for the process of cilia formation.
228 mework preserves spectral resolution, and in turn, sensitivity and specificity of the reconstructed i
233 rand antiparallel beta-sheet and two helical turns stabilized by a complex disulfide bond network tha
237 activate de novo serine synthesis, which in turn stimulates alpha-ketoglutarate-dependent dioxygenas
239 promoting the expression of TIMP-1, which in turn stimulates cell proliferation in an autocrine manne
240 220) The subsequent activation of IGPR-1, in turn, stimulates phosphorylation of AMP-activated protei
241 ion to neighboring yeasts against azoles, in turn strengthening their co-existence in hostile polymic
242 a larger corpuscular structure; greater beta-turn structure was also observed by synchrotron-Fourier
244 vocalization onto this scaffold in order to turn such jaw oscillations into vocalized syllables.
247 stems and the engagement of policy makers to turn surveillance findings into timely and effective dec
248 ynthesized from anteiso-methyl-palmitate, in turn synthesized from a precursor metabolite generated i
251 s that the use of parentese and parent-child turn-taking are both associated with advances in childre
252 e presented five pairs of chimpanzees with a turn-taking coordination game, where the task was to sen
254 esults complement Ritz's upper bound and may turn the computation of lower bounds into a staple of ei
256 verall activity site that can allosterically turn the enzyme on or off by the binding of ATP or dATP,
259 iCDI, the filled polyelectrolyte effectively turns the macropores into a charged ion-selective layer
260 anslation of reads into the monomer alphabet turns the notoriously difficult problem of assembling ce
267 ion temperature affect the structure and, in turn, the physical properties of ultrathin a-C films use
268 ously adjusting JH(2)O(2) production and, in turn, the rate at which energy is expended via NNT-media
270 and stability of the apical complex and, in turn, these discoveries have shed new light on the funct
276 s-driven in vitro and in silico approach, we turn to early and lower vertebrates and ask two fundamen
279 ing whether T2D is causal for CHD); and then turn to the implications of this genetic relationship fo
283 To build these models, researchers have turned to two complementary approaches: neuroimaging stu
287 the ability of HOTAIR to bind Snail and, in turn, trigger H3K27me3/EZH2-mediated repression of Snail
289 formation of 2'3'cGMP-AMP (cGAMP), which in turn triggers interferon (IFN) production via the STING
290 ng and the design of materials, which can in turn tune the functionality and biocompatibility of bioe
297 analogs designed to contain a disrupted beta-turn were dramatically less potent relative to their par
298 ence micellar behavior of bile salts, and in turn whether this affected the biological responses in c
299 Exploration into novel chemical space, in turn, will also improve drug solubility and pharmacokine