ライフサイエンスコーパス: turnover rate

1 r higher ee, good regioselectivity, and high turnover rates).

2 by the complexity of water currents or slow turnover rate.

3 ZSM-5 material, leading to a 460 times lower turnover rate.

4 viscosity that is inversely proportional to turnover rate.

5 and this protein possesses a relatively high turnover rate.

6 s and this protein displays a relatively low turnover rate.

7 site density and the species-specific sodium turnover rate.

8 nts for a second phase of the slow catalytic turnover rate.

9 increases in BZ contractile function and ATP turnover rate.

10 the human enzyme, indicated a reduced single turnover rate.

11 s but is caused by the significantly reduced turnover rate.

12 the increased hydrophobicity) decreased the turnover rate.

13 lecules, ultimately increasing the enzymatic turnover rate.

14 light conditions increased SAUR63:HA protein turnover rate.

15 self-ubiquitination and decelerating COP1's turnover rate.

16 t significantly reduce its maximum substrate turnover rate.

17 P2C concentration and equal to the observed turnover rate.

18 ccur on a timescale similar to the catalytic turnover rate.

19 0-fold faster, respectively, than the mutant turnover rate.

20 edox cycles and causes a 10-fold decrease in turnover rate.

21 in the isotope envelope to calculate protein turnover rate.

22 s accompanied by an increase in the filament turnover rate.

23 like Na(+) and K(+) affinities and catalytic turnover rate.

24 f the host-specific variation in NS3 protein turnover rate.

25 dominated by weak ties characterized by high turnover rates.

26 tial equations was used to calculate protein turnover rates.

27 the same miRNA can possess vastly different turnover rates.

28 30 nucleotides or fewer at comparable single-turnover rates.

29 ospinal fluid Abeta concentrations and Abeta turnover rates.

30 ort rates can be slow and comparable to mRNA turnover rates.

31 mation and compared with fluorescent product turnover rates.

32 range that strongly influenced CO oxidation turnover rates.

33 these mutants displayed a defect in protein turnover rates.

34 any cases are mediated by changes in protein turnover rates.

35 forming similar functions often have similar turnover rates.

36 stimulate replication-independent histone H3 turnover rates.

37 oupling of the proton pump but maintain high turnover rates.

38 2 species were relatively stable and had low turnover rates.

39 HRP but also bulk reactions at low substrate turnover rates.

40 ic oxidation and bioconjugation pathways and turnover rates.

41 ed decomposition of SOC components with slow turnover rates.

42 eous plants showed little change in temporal turnover rates.

43 ong effect on H2 oxidation and H2 production turnover rates.

44 exhibits an approximately 1,000-fold slower turnover rate (0.06-0.17 s(-1)), suggesting a potential

45 tion between increasing age and slowed Abeta turnover rates (2.5-fold longer half-life over five deca

46 8 g m(-2) yr(-1) ), and a trend of decreased turnover rate (6 +/- 1 times yr(-1) ).

47 rylation of LmjAQP1 led to a decrease in its turnover rate affecting LmjAQP1 activity.

48 ite in the ATPase yielded enzymes with lower turnover rates, although Cu(+) transfer was minimally af

49 ly 70 most abundant proteins, variability in turnover rates among rats was low (median coefficient of

50 tes: an autoinhibited basal state with a low turnover rate and a low H(+)/ATP coupling ratio and an a

51 are a distinctive TRM population with a high turnover rate and a unique phenotype influenced by their

52 e APT2, that each species varies in terms of turnover rate and activity, altogether allowing the cell

53 -fixing enzyme Rubisco, which exhibits a low turnover rate and can react with O2 instead of CO2 , lea

54 so estimated lipolysis (from [(2)H5]glycerol turnover rate and circulating free fatty acids, glycerol

55 ositive charge of the residue) increased the turnover rate and decreased the Km of AdoMet but did not

56 roton transfer, leading to an overall faster turnover rate and exclusive cis-amidopalladation of alke

57 67 and annexin V stainings revealed a faster turnover rate and increased apoptosis of Raptor-deficien

58 conformation of SERT can explain the reduced turnover rate and increased association rate of inhibito

59 re likely due to high biomass concentration, turnover rate and microbial activity in WWTPs, and likel

60 control alpha1beta1, FXYD1 reduces Vmax and turnover rate and raises K0.5Na.

61 signaling RNAs have high affinity and ATPase turnover rate and thus a high katpase/Kd.

62 of closed hexameric toroids capable of high turnover rates and amenable to allosteric regulation.

63 oxic or volatile pathway intermediates, slow turnover rates and competing side reactions.

64 d pulse-chase system, we measured population turnover rates and individual t1/2 of pre-established Ag

65 lity of pre-mRNA species with different high turnover rates and investigated potential correlations w

66 uman enzyme seems to restore both the single turnover rates and narrow distribution of fast dynamics.

67 noparticles with their support, so identical turnover rates and reaction selectivity is observed rega

68 CO oxidation turnover rates and the dynamics and thermodynamics of ad

69 he decomposition of SOC components with slow turnover rates and thus amplify the positive feedback to

70 Reversed phase HPLC provided multiple turnover rates and tryptophan fluorescence provided nucl

71 ing FGE with copper(II) is required for high turnover rates and yields.

72 owth rate, faster onset, higher steady-state turnover rate, and a greater volume of water collected c

73 e cells partially restored receptor density, turnover rate, and the structural integrity of the posts

74 ferent HIV-1 target cells may have different turnover rates, and it is not clear whether the bulk HIV

75 ists caused a substantial reduction in spine turnover rates, and the former was reversed by corticost

76 Both Npas4 mRNA and protein had high turnover rates, and, at the protein level, degradation w

77 from these conditions, they exhibit similar turnover rates, apparent activation energies and apparen

78 ietary intake over 2-3 y because of the slow turnover rate, appears promising but has so far been rar

79 is trafficking role, GRIP1b's palmitoylation turnover rate approaches the highest of all reported pro

80 timates of vegetation carbon pools and their turnover rates are central to understanding and modellin

81 Turnover rates are lower and kinetically relevant specie

82 Turnover rates are proportional to O(2) pressure and inv

83 stic interpretations of methanol dehydration turnover rates are used to assess how charge reorganizat

84 eptidoglycan decomposition exhibited similar turnover rates as their l-enantiomers.

85 ivity genotype (contributing to low dopamine turnover rate) as well as the CDH13 gene (coding for neu

86 or ADF/cofilin1, which mediates high F-actin turnover rates, as an essential factor in this process.

87 ehavior directly competes with the enzymatic turnover rate at physiological glucose concentrations, t

88 terminals but show significant and different turnover rate at the membrane.

89 t Tea1 and Mod5 exhibit distinctly different turnover rates at cell tips.

90 ve rise to a large increase in CH4 oxidation turnover rates at oxygen chemical potentials leading to

91 Total ATP turnover rate (ATPtot) was estimated at exercise cessati

92 There is considerable heterogeneity of turnover rates between promoters in different tissues, b

93 tivity, protein interactions, targeting, and turnover rate, but despite their importance, they are st

94 and rehabilitation units had the lowest mean turnover rates, but most differences between service lin

95 l cortex exhibited diminished baseline spine turnover rates, but these rates were also enhanced by co

96 is (mPDE), that resulted in decreased enzyme turnover rate compared with its unphosphorylated counter

97 filament subpopulations with very different turnover rates composed the actin cortex: one with fast

98 However, estimates of cardiomyocyte turnover rates conflict greatly, with a study employing

99 hat free F(1) was a newer pool with a faster turnover rate consistent with it being an assembly inter

100 Analysis of heavy water data sets yielded turnover rates consistent with a short blood half-life,

101 However, the single-turnover rate constant for alkylation does depend on the

102 t with the steady-state reaction, the single-turnover rate constant for dansyl-GCVLS alkylation was f

103 ease corresponds to the overall steady-state turnover rate constant, suggesting that product release

104 thenoadenine (epsilonA) from DNA with single-turnover rate constants that are 2.9 x 10(5)-fold greate

105 Single-turnover rate constants were slowed for heavy PNP, demon

106 H, explains the structural origin of the ATP turnover rates detected in relaxed tarantula muscle by a

107 permanent extensive remodeling, but how the turnover rate differs between lipid classes and molecula

108 e shorter-lived, and exhibit higher baseline turnover rates distinct from AMs.

109 gher local concentration and a faster enzyme turnover rate due to a closer proximity of genes.

110 erary of the cadherin, resulting in a higher turnover rate due to decreased recycling and increased d

111 otein levels while intact exhibited a higher turnover rate during activation of switching to IgG3 and

112 e.g., growth rate), community (e.g., biomass turnover rates), ecosystem (e.g., trophic pyramids), and

113 O-GlcNAcylation, which maintained the rapid turnover rate even in the presence of GlcN and increased

114 This DNA-dependent ATP turnover rate exhibits a dependence on the concentration

115 K(+)-ATPase retained a wild-type-like enzyme turnover rate for ATP hydrolysis and rate of cellular K(

116 This enrichment resulted in turnover rates for an additional 17 proteins.

117 Turnover rates for condensation and esterification react

118 rates of DNA damage and were converted into turnover rates for enzymic production of DNA-reactive me

119 A comparison of the turnover rates for H2 and O2 revealed that in the presen

120 ied nitrogen (N), phosphorus (P) and caloric turnover rates for Lake Huron lake trout, and reveal how

121 Turnover rates for mixed alkenes give relative alkoxide

122 Turnover rates for monomolecular cracking and dehydrogen

123 Catalytic turnover rates for most Val3 mutants are only slightly d

124 Previously published turnover rates for this DUS were very low.

125 regional differences, and the high regional turnover rates found challenge the universal concept of

126 hosphatidylcholine increases the Na,K-ATPase turnover rate from 5483 +/- 144 to 7552 +/- 105 (p < 0.0

127 ution of forward ET rates is higher than the turnover rate from ensemble steady-state measurements an

128 ng a reference dataset of 496 plasma protein turnover rates from 4 healthy adults.

129 generated DNA oxidation and adduct formation turnover rates from the array correlated very well with

130 The force-generating cross-bridge turnover rate (g) and the energy cost (ATPase/force) wer

131 edicted to experience >10% increases in root turnover rates given potential shifts in tree species co

132 r ammonia emissions than if historical fleet turnover rates had prevailed.

133 tion in skeletal muscle, a tissue with a low turnover rate, has never been investigated.

134 We observed that Rad17 protein turnover rate in breast epithelial cells is much faster

135 thways results in an increased mitochondrial turnover rate in GCN5L1(-/-) cells.

136 showed a large decrease in the cross-bridge turnover rate in Tg-D166V muscle compared to Tg-WT, the

137 s, and quantitative RT-PCR revealed a higher turnover rate in the humerus than in lumbar vertebrae, s

138 hols, while numerous steps contribute to the turnover rate in the oxidation of aliphatic alcohols.

139 rats in vivo, measure variability of protein turnover rates in any animal model, and utilize activity

140 We measured miRNA turnover rates in eight mammalian cell types with a comb

141 te and 2,4,6-trichlorophenol also gives high turnover rates in enzymatic studies.

142 a, possibly relating to the modified protein turnover rates in heterotrophic plastids.

143 This paper focuses on new nurses' unit-level turnover rates in hospitals.

144 on under future climate scenarios while root turnover rates in other portions of the eastern US were

145 slide to observe their individual substrate turnover rates in parallel by fluorescence microscopy.

146 s the first to measure global plasma protein turnover rates in rats in vivo, measure variability of p

147 inant processes that shape vegetation carbon turnover rates in real forest ecosystems at a large spat

148 le of the polymerase fidelity and nucleotide turnover rates in recombination.

149 hotometric measurements suggest that aqueous turnover rates in SPARC-null mice are equal to if not gr

150 CO2 was also associated with faster nutrient turnover rates in the first six months of the experiment

151 e to <1% per year in adulthood, with similar turnover rates in the major subdivisions of the myocardi

152 ned model identified patterns of faster root turnover rates in the North Central US and slower turnov

153 ver rates in the North Central US and slower turnover rates in the Southeastern US.

154 hotometric measurements suggest that aqueous turnover rates in TSP1-null and TSP2-null mice are great

155 is of in vitro degradation rates and protein turnover rates in vivo of specific proteins indicated th

156 TECs; 2) whereas cTECs and mTECs had similar turnover rates in young mice, the turnover of mTECs was

157 We found that differences in biomass turnover rates influenced F : B under conditions of C li

158 on for a wide range of conditions, but their turnover rate is high.

159 ) and closed (active) state, and the overall turnover rate is inversely proportional to the lifetime

160 The turnover rate is mainly determined by the alkene coordin

161 where measurement of amino acid and protein turnover rates is accomplished using a heavy water label

162 knowledge of the root carbon pool sizes and turnover rates is limited.

163 he large number of single molecule substrate turnover rates is representative of the activity distrib

164 re primarily due to changes in the catalytic turnover rate (k(cat)) and not in the affinity for the s

165 PR by an order of magnitude, affecting both turnover rate (k(cat)) and substrate affinity (K(m)).

166 VISIT) using estimates of vegetation carbon turnover rate (k) derived from a combination of remote s

167 Apparent turnover rates (k(cat,app)) of the reconstituted enzymes

168 he binding constant (K(D)) and the catalytic turnover rate, k(cat).

169 At -1 degrees C, the Rubisco turnover rate, kcat (c) , was 0.4 C s(-1) per site and t

170 on the reaction, catalyst resting state, and turnover-rate limiting step has been examined.

171 tification of the catalyst resting state and turnover-rate limiting step.

172 light-harvesting and surface-area-normalized turnover rates, making Y2 Ti1.94 Rh0.06 O7 an excellent

173 rity exhibit dynamic instability with higher turnover rates nearer to the midzone.

174 y of the inhibition and the very low protein turnover rate observed for the enzyme are particularly r

175 eduction is at least 10-fold faster than the turnover rate observed with unlabeled or [4,4,5,5,6,6-D(

176 imethylsilyl)amine is formed with an initial turnover rate of 1 N(TMS)3/min, ultimately reaching a tu

177 constant of 4.3 s(-1), also faster than the turnover rate of 1A.

178 lar system is 1.1 min(-1), comparable to the turnover rate of a truncated trimodular derivative (2.5

179 show that the Leu-Phe substitution increases turnover rate of acetaldehyde but decreases turnover rat

180 f the postsynaptic apparatus is altered, the turnover rate of AChRs increases significantly, and the

181 At the adult alpha-syn(-/-) NMJ, the turnover rate of AChRs is approximately 4 times faster t

182 how that actin phosphorylation increases the turnover rate of actin filaments and promotes the short-

183 ctin can work in concert to increase the ATP turnover rate of actin.

184 f guppies (Poecilia reticulata) to study the turnover rate of alleles (temporal genetic differentiati

185 equired for V(D)J recombination and that the turnover rate of APE2-deficient progenitor B cells is ne

186 o-photon microscopy and determined the spine turnover rate of apical dendrites of layer 5 (L5) and L2

187 There was an increased turnover rate of authors in the select agent community t

188 ments demonstrated that KChIP2 decreases the turnover rate of cell surface Kv4.2 protein by inhibitin

189 A mutant exhibited an increase in the single-turnover rate of correct nucleotide insertion.

190 gap junction communication by increasing the turnover rate of Cx43 from the plasma membrane.

191 The K m value and turnover rate of CYP71AN24 for phenylacetaldoxime were 3

192 ent of particulate antigen secretion and the turnover rate of cytoplasmic protein.

193 ations dramatically reduced the biosynthetic turnover rate of DE-Cad during apical-basal polarization

194 lear bomb test-derived (14)C revealed a high turnover rate of endothelial cells throughout life (>15%

195 growth and root respiration, as well as the turnover rate of fine-root C fixed during [CO(2)] fumiga

196 absolute (molar) abundance and determine the turnover rate of glycerophospholipids and sphingolipids

197 Using electrochemical measurements of the turnover rate of hydrogenase, we could resolve the first

198 turnover rate of acetaldehyde but decreases turnover rate of larger aldehydes.

199 +/- 0.015 (nilotinib) per day represents the turnover rate of leukemic differentiated cells, whereas

200 /- 0.0013 (nilotinib) per day represents the turnover rate of leukemic progenitor cells.

201 Because of the rapid turnover rate of membrane Hsp70, fluorescently labeled T

202 We measured the nucleotide turnover rate of myosin in tarantula leg muscle fibers b

203 y after photobleaching (FRAP) to examine the turnover rate of myosin VI during endocytosis.

204 The turnover rate of NRX1beta is attenuated by neural activi

205 ceptor density was dramatically reduced, the turnover rate of receptors at synaptic sites was signifi

206 munities, with possible consequences for the turnover rate of soil carbon (C) pools and feedbacks to

207 individual site, indicating that the spatial turnover rate of soil microbial communities was accelera

208 strate that extramatrix Ca(2+) modulates the turnover rate of the APC and not the binding affinity of

209 The maximum turnover rate of the complete hexamodular system is 1.1

210 to N lobe Ca2+ binding site 1 increases the turnover rate of the enzyme 5-fold, whereas the C lobe p

211 ubstrate-binding function from the catalytic turnover rate of the enzyme.

212 However, the maximal single turnover rate of the FEN EXO reaction also yields a near

213 ults in a dramatic increase in the catalytic turnover rate of the POM for air-based oxidations.

214 n the mammalian circadian clock involves the turnover rate of the repressors CRY and PER.

215 It allows determination of the turnover rate of the substrate and the kinetic constants

216 ically distinct substrates by increasing the turnover rate of the substrate with nominally lower affi

217 These findings indicate a low basal turnover rate of the total KCC2 protein pool.

218 ubstrates, lysozyme exhibited processive low turnover rates of 20-50 s(-1) and rapid (200-400 s(-1))

219 of (14)N-labeled proteins, we calculate the turnover rates of 508 different proteins in barley and s

220 oaches to compare the relative abundance and turnover rates of 848 and 196 proteins, respectively, in

221 Turnover rates of A(g7) and H2-A(d) were indistinguishab

222 ganism-wide isotopic labeling to measure the turnover rates of approximately 2,500 proteins in multip

223 f Fe and Zn per polypeptide and demonstrates turnover rates of approximately 3 s(-1) Similar rates ar

224 rates (r(2) = 0.68, P < 0.05), and that the turnover rates of both leaf (r(2) = 0.63, P < 0.05) and

225 abolic scaling theory, we show that isotopic turnover rates of carbon and nitrogen in whole organisms

226 Our findings suggest that the higher turnover rates of carbon pools in semi-arid biomes are a

227 educed Km and increased multiple- and single turnover rates of endonucleolytic hydrolysis at near phy

228 el regularities: condition invariant in vivo turnover rates of enzymes and the correlation of protein

229 Measuring whole-body turnover rates of glucose and FFAs in L-AktFoxo1TKO mice

230 l properties depend strongly on the relative turnover rates of its constituents, but quantitative dat

231 beling allowed the concurrent measurement of turnover rates of multiple natural products from small a

232 the thick filament modulates the nucleotide turnover rates of myosin in relaxed fibers.

233 ents, fractional synthetic rates, and plasma turnover rates of n-3 FAs.

234 Because increased turnover rates of new soil C limit the potential for add

235 and suggest that elevated CO2 might increase turnover rates of new soil C.

236 of supporting productive T cell development, turnover rates of niche occupancy, and feedback mechanis

237 Here, turnover rates of plasma proteins in rats were measured

238 protein-protein interactions, and control of turnover rates of proteins.

239 ation in synaptic plasticity, as well as the turnover rates of specific neuronal proteins.

240 is demonstrated by the determination of the turnover rates of the enzyme using the Michaelis-Menten

241 nt choice significantly affected binding and turnover rates of the recombinant enzymes with various x

242 Consistent with the intrinsic turnover rates of their transcripts and proteins, antiap

243 perties that determine the selectivities and turnover rates of these catalysts have not yet been eluc

244 irements, pathway delineation and metabolite turnover rates) of Clostridium carboxidivorans P7, a mod

245 ncomitant reduction of the maximal catalytic turnover rate or expression level.

246 dicating either a small pool size or a rapid turnover rate (or both) of GAA.

247 esolved issue whether differences in Aux/IAA turnover rates played a significant role in plant respon

248 lly and an increase in vesicle pool size and turnover rate presynaptically, adaptive changes that ext

249 ), while the linear rise was associated with turnover rates (r = 0.28; P < .05).

250 tive relationship between leaf and fine root turnover rates (r(2) = 0.68, P < 0.05), and that the tur

251 ms, the accumulation of N in pools with slow turnover rates reduces N available for plant uptake and

252 Spontaneous spine turnover rates remain high in older Tg1 animals compared

253 tments, in-stream PUCs characterized by fast turnover rates, such as filamentous algae, showed the hi

254 Production and turnover rates suggest that day/night Abeta patterns are

255 deletion of Lynx1 doubled the baseline spine turnover rate, suggesting that the spine dynamics in the

256 through specific sequences and can regulate turnover rates, suggesting a novel posttranscriptional r

257 Follicular B cells had higher turnover rates, survived poorly after adoptive transfer,

258 of H(2), propanal, and propanol pressures on turnover rates, taken together with measured selectiviti

259 gradual slowing of the RC electron transport turnover rate (tau(QA)) from ~1.6 to 6.4 ms and an ~3-fo

260 ted a higher physiological baseline monocyte turnover rate than adults.

261 AE protease has a lower catalytic turnover rate than clade B protease, and it also has wea

262 0.9-kDa subunits, had a significantly higher turnover rate than intact CI or CI+CIII(2).

263 r nicotinamide adenine dinucleotide (NAD(+)) turnover rate than normal cells, making this biosyntheti

264 apparent Ca(2+) affinity and a lower maximal turnover rate than the purified sarco(endo)plasmic retic

265 reactivity, with up to 4 times higher local turnover rates than those of the parent H-ZSM-5 crystals

266 ize may be related to changes in the subunit turnover rate that are independent of the GTP hydrolysis

267 und pool, and a dynamic bound pool with high turnover rate that exchanges with the cytoplasmic pool.

268 y influenced by steric constraints, yielding turnover rates that increase by up to two orders of magn

269 Conversely, IMs exhibited higher turnover rates that were similar to those of blood monoc

270 n ergosterol accrual in ingrowth cores), and turnover rate (the quotient of annual production and ave

271 led that SOS samples a broad distribution of turnover rates through stochastic fluctuations between d

272 of AMs, and these cells maintained the lower turnover rate throughout the duration of infection.

273 ied a suppressor mutation that increases the turnover rate to restore the specific activity of the hi

274 also allow plant carbon pool sizes and their turnover rates to be predicted from the single readily q

275 Enzyme turnover rates using the microsomal bioreactors were 2-3

276 e A673T substitution modulates the catalytic turnover rate (V(max)) of APP by the BACE1 enzyme, witho

277 lgeranyl diphosphate was 18.7 microm, with a turnover rate value of 6.85 s(-1).

278 oduction was 279 +/- 63 g m(-2) yr(-1) , and turnover rate was 10 +/- 3 times yr(-1) .

279 e the enzymatic reduction of N2 into NH3 The turnover rate was 75 per minute, 63% of the ATP-coupled

280 xposure to glucose, a steady-state enzymatic turnover rate was detected through amperometric oxidatio

281 Mean ATP turnover rate was not different between protocols ( appr

282 iously that a high peripheral blood monocyte turnover rate was predictive for the onset of disease pr

283 de was integrated into ER membranes, and its turnover rate was sensitive to proteasome inhibition.

284 type control mice, whereas the GI eosinophil turnover rate was unaltered in the absence of CD22.

285 Based on the measured turnover rates we have established a quantitative, singl

286 Based on global population sizes and turnover rates, we estimate that these species have the

287 ECL turnover rates were defined by R, the initial slope of E

288 elial cells (ECs), and fibroblasts and their turnover rates were measured by retrospective (14)C birt

289 nursing staff turnover and registered nurse turnover rates were modeled as dependent variables in hi

290 rred among some microbial additions, similar turnover rates were observed, and in general, results do

291 on differentiation, numerous changes in H3.3 turnover rates were observed, the majority of which occu

292 approach, 273 proteins were identified, and turnover rates were quantified for 157 plasma proteins w

293 Lipid turnover rates were studied by pulse-chase experiments a

294 new nurses work in hospitals and have higher turnover rates when compared to experienced nurses.

295 nkton communities displayed slower community turnover rates when dominated by few genera.

296 ved NK cell expansion was not due to altered turnover rate, whereas it was associated with preferenti

297 anisms may be used in cells to tune filament turnover rates, which can vary widely for different acti

298 Measured protein turnover rates will be important for understanding of th

299 that S. pyogenes has an unusually high mRNA turnover rate, with median and mean half-lives of 0.88 m

300 through which cells can maintain high actin turnover rates without having to alkalinize cytosol, whi