ライフサイエンスコーパス: twist

1 e similar to the mesodermal master regulator Twist.

2 hiral rods form flat disks with uniform edge twist.

3 omoted the non-degradative ubiquitination of Twist.

4 -deoxyguanosine with a significant propeller twist.

5 ymes, in the twister ribozyme there may be a twist.

6 ile an S configuration induced a MPM helical twist.

7 cer metastasis, recapitulating the effect of Twist.

8 and division plane orientation but not root twisting.

9 including pressing, stretching, bending, and twisting.

10 hich was consistent with elevated Gli-1/2 or Twist-1 protein levels in the nuclear fraction.

11 but is accompanied by the overexpression of TWIST-1, a transcription factor highly expressed in resi

12 in (median values: -17.7% versus -19.5%), LV twisting (12.4 degrees versus 14 degrees ), %untwMVO (27

13 ormation of the P1 intermediate exhibiting a twisted 13-cis retinal with a 110 +/- 7 fs time constant

14 dinal strain (25% versus 17% versus 6%,), LV twist (27% versus 17% versus 1%), %untwMVO (31% versus 2

15 port measurements demonstrate that while the twisted 3,7-NDA-based P1 is a poor semiconductor, the pl

16 been described that is able to mechanically twist a bound molecular guest, and molecular fragments h

17 In both structures, three copies of VP35 twist about each other to form a coiled coil.

18 nation is a crucial regulatory mechanism for Twist activation.

19 on effect) earlier discussed for 90 degrees -twisted alkenes is observed and calculated for planar ri

20 hese nanoribbons results in a high degree of twisting along the long axis.

21 ctivated arrestin-3 exhibits an inter-domain twist and a displaced C-tail, hallmarks of active arrest

22 LV twist and apical rotation were not altered from baseline

23 for lower concentrations and is relieved via twist and bend deformations in this unique configuration

24 roach to combat metastatic CRPC by targeting Twist and CSCs.

25 the meta-molecules, since all the components twist and deform into the same chiral configuration when

26 In spite of the tripodal linkage, a smooth twist and efficient pi overlap are preserved.

27 ater average values of stagger, slide, rise, twist and h-rise than observed for a 'control' oligonucl

28 icant relationships were observed between LV twist and LV internal diameter and sphericity index in f

29 l correlates with the capacity of motif V to twist and order in the SaPI-inducing disposition, while

30 ns employed here are a combination of p-fold twist and polar glide.

31 Mechanistically, Skp2 interacted with Twist and promoted the non-degradative ubiquitination of

32 s not only exhibited nuclear localization of Twist and Slug, markers of epithelial-mesenchymal transi

33 ployed by the developmental regulatory genes twist and snail [7-10].

34 , in a manner that mimics how plant tendrils twist and turn under the effect of differential expansio

35 ergic receptor blockade, LV apical rotation, twist and untwisting velocity were reduced in males comp

36 n depends upon its initial partitioning into twist and writhe as determined by tension.

37 gth of the DNA and relative contributions of twist and writhe to the chromosome's negative supercoili

38 This twisted and rehybridized intramolecular charge transfer

39 materials are capable of controlling complex twisting and bending deformations simultaneously or sepa

40 This resulted from both N-domain twisting and rotation of the C domain (up to 30 degrees

41 wisting, and percent difference between peak twisting and untwisting at mitral valve opening (%untwMV

42 The journey was not without its twists and turns, but the unexpected often led to new re

43 tor bead tracking (RBT) measures DNA torque, twist, and extension, and can be used to characterize th

44 e average cooperativity was sensitive to DNA twist, and was strongest when the DNA was slightly under

45 quired for its function in root growth, root twisting, and division plane orientation.

46 duced motions, including expansion, bending, twisting, and jumping.

47 measured (1) LV global longitudinal strain, twisting, and percent difference between peak twisting a

48 multilayer graphene by the introduction of a twist angle between different layers to create van Hove

49 rization and is only weakly dependent on the twist angle between layers.

50 ve singularities whose energy depends on the twist angle between the two layers.

51 er than the imaginary part, with the highest twist angle chromophore giving |Re(gamma)/Im(gamma)| app

52 ir evolution are systematically studied with twist angle in bilayer and trilayer graphene sheets.

53 The twist angle increases with the increase of deformation a

54 adopts a twisted backbone with an end-to-end twist angle of 28 degrees that was unambiguously confirm

55 To explain this behavior with twist angle, the energy separation of the van Hove singu

56 ent is attributed to the emergence of unique twist-angle-dependent van Hove singularities, which are

57 HSs in bilayer graphene over a wide range of twist angles (from 5 degrees to 31 degrees ) with wide t

58 the aromatic bridges gradually increases the twist angles between the two PDI planes, leading to a va

59 he Raman G peak area initially increases for twist angles larger than a critical angle and decreases

60 Most Tau fibers have a twisted appearance, but the twist can be variable and ev

61 However, strategies that directly target Twist are not yet conceivable.

62 Quantum chemical calculations reveal a twist around the acetylene bridging unit to be the respo

63 h organometallic reagents, are intrinsically twisted around the N-C(O) axis.

64 ap of tetracene pi-orbitals, and BET-B, with twisted arrangement between tetracenes exhibits less ove

65 These devices consist of twisted assemblies of thin, highly stretchable (>400%) e

66 tivates TWIST1 promoters, and that this SPZ1-TWIST axis mediates EMT signaling and exerts significant

67 e bay region, the chiral peropyrene adopts a twisted backbone with an end-to-end twist angle of 28 de

68 studied the C3 promoter and identified that twist basic helix-loop-helix transcription factor 1 (TWI

69 nel conserve, for a characteristic time, the twisting behavior of the stable limit cycle destroyed in

70 ncy of the stability of both the nematic and twist-bend mesophases upon this angle, thereby satisfyin

71 re dictates the stability of the nematic and twist-bend nematic mesophases.

72 he transition between the normal nematic and twist-bend nematic with spontaneous breaking of chiral s

73 -yl) hexane (CB6OABOBu), shows enantiotropic twist-bend nematic, NTB, and nematic, N, phases.

74 ibit a phase transition from the heliconical twist-bend phase into a lamellar smectic A mesophase, ad

75 indicating an unexpected sensitivity of the twist-bend phase to molecular structure.

76 -terminal alpha/beta region and a C-terminal twisted beta barrel-like domain.

77 This second beta-carotene has highly twisted beta-rings adopting a flat conformation, which i

78 hat 1-108-alphaS fibrils consist of strongly twisted beta-sheets with an increased inter-beta-sheet d

79 low symmetry conformations, due to dihedral twists between neighboring porphyrin units, but their sy

80 The electronic band structure of twisted bilayer graphene develops van Hove singularities

81 ify the electronic and optical properties of twisted bilayer graphene with doping.

82 iguration is observed with a predominance of twisted bipolar tactoids.

83 e addition by negative hyperconjugation; the twist-boat conformation of the addition and intermediate

84 tions which force a six-membered ring into a twist-boat conformation.

85 ch are characterized to contain a 6-membered twist-boat ring.

86 e (1)H NMR time scale between the two chiral twisted-boat conformers of the chelated COD included in

87 ment spacing leads to optimal shapes of self-twisting bundles that break the symmetries of packing an

88 ion by preventing proteasomal degradation of Twist by beta-TrCP.

89 d then replaced, whereas left testicles were twisted by 360 degrees in group 2.

90 au fibers have a twisted appearance, but the twist can be variable and even absent.

91 Chiral twist can contribute to the behavior of both systems and

92 ew understanding of the structure around the twisted chromophore enabled the design of a mutant that

93 ty at chromophore thiophene rings and (ii) a twisted chromophore geometry, producing a manifold of cl

94 reveal how cofilin enhances the bending and twisting compliance of actin filaments.

95 sensors and interconnects formed from thin, twisted conductive microtubules.

96 the excited states assumes a near-canonical twisted configuration halfway between the trans and cis

97 This twisted conformation allows for intercalation of the rel

98 versus tren unit triggers a planar-to-singly twisted conformational change and hence a Huckel antiaro

99 Thus, pleiotropic functions of TWIST control vascular disease and development.

100 shape-persistent, triangular structures with twisted cores and internal diameters up to approximately

101 siders the collective behavior of the double-twist cylinders.

102 chirality leads to ordered arrays of double-twisted cylinders over micrometer scales.

103 lline array, without diffusion of the double-twisted cylinders.

104 3D-magnetic twisting cytometry (3D-MTC) is a technique for applying

105 ed by single-cell contraction using magnetic twisting cytometry (MTC).

106 ing cell by using three-dimensional magnetic twisting cytometry to apply local stresses on the cell s

107 Bending and twisting deformations can be created under IR irradiatio

108 the handedness of the substrate's macroscale twist determining the handedness of the S-like chains.

109 how that a free-standing web of 1/2-strength twist disclination lines can be stably formed in thin li

110 a very stable freestanding 3D array of (1/2) twist disclinations, which could be exploited in a varie

111 rved energy-dependent momentum structure and twisted dispersion of spin excitations near (pi, pi) are

112 torque produced by RNAP motion on helically twisted DNA can explain this apparent paradox.

113 simulations, we show that the field-induced twisted domain nucleus formed at domain walls results in

114 identification of two new mutant alleles of TWISTED DWARF 1 (TWD1), twd1-4, and twd1-5.

115 ilin only weakly alters filament bending and twisting dynamics and therefore does not introduce the m

116 terial properties such as helical pitch, the twist elastic constant, and the interfacial tensions, is

117 nanocomposites, made by conformally coating twisted elastic substrates with films assembled layer-by

118 plane magnetic field by interfering a highly twisted electron vortex beam with a reference wave.

119 fects on cofilin occupancy, whereas filament twisting enhances cofilin dissociation without compromis

120 TWIST expression promotes developmental angiogenesis by

121 Twist expression was generalised in the epithelium in no

122 nd for the activation of Pt-hunchback and Pt-twist expression.

123 Further, our data suggest TWIST1 (twist family basic helix-loop-helix transcription factor

124 structures, validating the importance of the Twist-family bHLH dimer pool in limb morphogenesis.

125 anisms and potential applications of present twisted fiber muscles and the future opportunities and c

126 Focusing on twisting fibrils with an inter-crossover spacing of 77 n

127 A magnetic twisting field in a different direction is then applied

128 Bellinger and colleagues offer an elegant twist for a promising new tool against malaria.

129 ictable and large spectral shift (2.0 nm/deg twist) for morpholine deformations within these fairly f

130 :-bp on every basal plane and the 30 degrees twist GB is characterized with a stacking faulted struct

131 In particular, 30 degrees tilt and twist GBs are corresponding to energy minima.

132 tions explored that both 30 degrees tilt and twist GBs are highly mobile associated with collective g

133 rent from reported PDI-tetramers with highly twisted geometries and can explain the better performanc

134 are associated with a buckled and propeller-twisted geometry of the basepair.

135 dyes' absorption maxima originates from the twisted geometry of the N-aryl groups.

136 slocation structures of both <0001> tilt and twist grain boundaries (GBs) in Magnesium.

137 another important type of grain boundaries, twist grain boundaries, have long been overlooked.

138 s stacked by van der Waals coupling, such as twisted graphene and coupled graphene-BN layers with unu

139 ption factor clusters of beta-catenin/Snail1/Twist has been implicated in the process of epithelial m

140 Twist has been shown to cause treatment failure, cancer

141 Accordingly, we propose the name hand-twisted helical crystals for these substances.

142 strategy is outlined for the design of hand-twisted helical crystals.

143 oad and static DNA shape features, Propeller twist, Helical twist, Minor groove width and Roll.

144 ns indicate that the [1,2-a]-isomer adopts a twisted, helical C2-symmetric structure and that its pro

145 tant helicity state after the dissipation of twist helicity by viscosity.

146 Here we report on new twisted hemithioindigo photoswitches enabling two differ

147 in is also reported and highlights a unique, twisted hinge region of ISG15 that is not conserved in h

148 t Glu29 residue encoded by hlh-8, the single Twist homolog present in Caenorhabditis elegans.

149 dination chemistry, which we call the pterin twist hypothesis.

150 The strips twist in opposite directions and work against each other

151 Furthermore, we found that a 90 degrees twist in subunit orientation leads to a peculiar quatern

152 mutant in Arabidopsis thaliana that displays twisting in petals and roots, at the organ and cell leve

153 anging scenarios, e.g., based on bending, or twisting in prescribed directions, are enabled via the c

154 s are associated with charge transfer due to twisting in the lowest singlet excited state.

155 uoroarene-arene (ArF-ArH) interactions cause twisting in the PE backbone, interrupting intramolecular

156 at on C7 retarded the charge transfer due to twisting in the structure caused by the butyl group.

157 structures that guide crack propagation and twisting in three dimensions, which we have followed usi

158 otein expression of beta-catenin, Snail1 and Twist, in these subject groups in 3 large airways compar

159 stituted BDI systems leads to a zwitterionic twisted intermediate state ((1)p*) and that destabilizin

160 group on the B-phenyl substituent creates a twisted intramolecular charge transfer state that causes

161 planation involves formation of highly polar twisted intramolecular charge-transfer species in the ex

162 eptor moieties, similar to that proposed for twisted intramolecular charge-transfer states.

163 Twist is a key transcription factor for Epithelial-mesen

164 ubstantial chiral induction of the molecular twist is achieved using chiral amino ligands (diastereom

165 The mechanosensitive transcription factor TWIST is expressed during embryogenesis, but its role in

166 Strikingly, the twisting is always left-handed and is not due to underly

167 subjected to intercalators and the amount of twisting is concentration dependent, and (ii) twisting s

168 We also show that, through twisting, it is possible to control their mechanical per

169 ydrodynamic instabilities or rotation of the twisted jet cause different jet regions to change their

170 Now in an unexpected twist, King and colleagues have expanded the repertoire

171 gned to the planar (kobs < 10(12) s(-1)) and twisted (kobs approximately 10(10) s(-1)) structures bet

172 aman backscattering can generate and amplify twisted lasers to petawatt intensities in plasmas.

173 and evaluate the effects of compressive and twisting loads on strain energy distribution at specific

174 romoted Twist ubiquitination is required for Twist localization to the nucleus for subsequent EMT and

175 , a simple class of aromatic foldamers, into twisted macrocycles.

176 eg, females: 8.8 +/- 2.3 deg, P = 0.007) and twist (males: 8.6 +/- 1.9 deg, females: 10.7 +/- 2.8 deg

177 LV twist mechanics are reduced in males compared to females

178 tion, providing preliminary evidence that LV twist mechanics may be more sensitive to adrenergic cont

179 These findings suggest that LV twist mechanics may be more sensitive to alterations in

180 vasiveness ability of breast cancer cells in Twist-mediated EMT.

181 30%) or independent ( approximately 70%) of Twist-mediated EMT.

182 We revealed that Skp2 regulates CRPC through Twist-mediated oncogenic functions including epithelial-

183 DNA shape features, Propeller twist, Helical twist, Minor groove width and Roll.

184 ng occurs through the activation of a domain twist mode by the binding of [Formula: see text] that oc

185 arp absorption edges that are defined by the twisted molecular conformation.

186 Despite its twisted molecular framework, NITI shows a low optical ba

187 The design is based on a series of helically twisted molecular ribbons as the optoelectronic material

188 ty reversal is associated with a spontaneous twisting motion around the DNA bridge caused by the larg

189 large tuning range of vHS binding energy in twisted multilayer graphene provides a promising materia

190 opportunities and challenges for developing twisted muscles having improved cycle rates, efficiencie

191 -open, V-shaped dimer in the apo state and a twisted, N-terminally closed dimer with ATP.

192 ine polymer fibers; nanocomposite actuators; twisted nanofiber yarns; thermally activated shape-memor

193 Overall, our observations suggest that the twisted nature of the five adjacent aryl groups serves t

194 The CLC in lying state, in both planar and twisted nematic cells, exhibits reversible in-plane orth

195 , we design two complex director fields with twisted nematic domains and nematic disclinations that e

196 Leveraging the twisted-nematic orientation, irradiation with broad spec

197 erin cofactors, in a variant of the Ray-Dutt twist of classical coordination chemistry, which we call

198 -responsive out-of-plane distortions such as twist of different chirality, emergence of cones, simple

199 with opposite chiralities can have the edge twist of either handedness.

200 e other ZnF arrays, follows the right-handed twist of the DNA, with the alpha helices occupying the m

201 ct helical arrangement and the super-helical twist of the flagellin subunits within the filaments.

202 nt of three helices is prescribed by the net twist of the middle segment, providing simple geometric

203 y interface, although small variation in the twist of the rod-likeHA trimer limited the overall resol

204 these structured topologies, leading to the twist of their circuitation on the Poincare sphere of po

205 In this study, we demonstrate global twisting of DNA nanorails made from two DNA origami six-

206 ng cell wall polymers is to suppress helical twisting of expanding plant cells.

207 helix away from the 4-fold channel axis and twisting of Ile-4937 at the channel constriction site ou

208 HiNmlR enhances target gene transcription by twisting of operator DNA sequences in a two-gene operon

209 ensions, shows that the length and degree of twisting of peptide fibrils seem to be influenced by the

210 -responsive molecular switch that drives the twisting of strips of liquid-crystal elastomers.

211 , the other half originates in the localized twisting of the Cbeta-Calpha-Calpha-Cbeta dihedral angle

212 ch other, allows for the possibility of hand-twisting of the crystals to give grossly helical morphol

213 ng these nonminimum structure effects, i.e., twisting of the enone chromophore and nonplanarity of th

214 des of collective motions featuring shearing/twisting of the extracellular domains relative to the TM

215 -mortar stacking of platelets and microscale twisting of the fibres--gives rise to high stretchabilit

216 and also provide a plausible mechanism for a twisting of the IkappaBalpha ARD induced by interactions

217 ssign to nonspecific deformation (unwinding/"twisting") of DNA by Rad4.

218 ne influences of DNA secondary structure and twist on protein-protein interactions in cooperative AGT

219 A new twist on this strategy has recently appeared, in which t

220 hamber that binds the clamp at its base in a twisted open form and encloses ptDNA within, while bindi

221 that Rad4 recognizes lesions in a step-wise "twist-open" mechanism, in which preliminary twisting rep

222 energy tendrils implies that as the tendrils twist or bend, strain must accumulate until nucleation o

223 on roll, while Dinterare mainly sensitive to twist or slide.

224 Shape-changing hydrogels that can bend, twist, or actuate in response to external stimuli are cr

225 se supramolecular constructs encompasses two twisted [organo-Pt(II)<--pyridine] coordination based ir

226 The MB2 planes significantly twist out of the MX2 planes about the M-centroid(B-B) ve

227 is is attributed to the triazole group being twisted out of conjugation in the developing benzylic ra

228 We found that Twist overexpression augments CSC self-renewal and popul

229 Here we report that Twist overexpression increased expression of PAR1, an up

230 LV apical rotation (P = 0.036) and twist (P = 0.029) were reduced in males with beta1 -AR b

231 bonds in solution state and into an uncommon twisted parallel beta-sheet through intermolecular H-bon

232 onding with the substrate, and creation of a twisted peptide bond involving this carboxylate and the

233 of the carboxylate metal ligand, a resulting twisted peptide bond, and the off-line geometry for diox

234 compound, such as rise per turn and helical twist per dimer, are nearly identical to this DNA confor

235 etal epidermal cells, leading to left-handed twisted petals.

236 Photons with a twisted phase front carry a quantized amount of orbital

237 f coherent twin boundaries and semi-coherent twist prismatic-prismatic boundaries that control twin g

238 macrofibers involving a wet-drawing and wet-twisting process of ultralong bacterial cellulose nanofi

239 typical magnetic cloud possessing a similar twist profile obtained by the Grad-Shafranov reconstruct

240 Chiral twist promotes the formation of finite-sized rafts and m

241 Consequently, Skp2 stabilized Twist protein expression by preventing proteasomal degra

242 tching is achieved for compounds that have a twisted (rather than T-shaped) Z isomer conformation.

243 Undoing the twist: Recent successful attempts to change the relative

244 movement disorder that forces the body into twisting, repetitive movements or sometimes painful abno

245 "twist-open" mechanism, in which preliminary twisting represents Rad4 interconverting between search

246 om an unstructured peptide to mature amyloid twisted-ribbon fibrils over a few hours when incubated o

247 e rotates forming many-turn Mobius strips or twisted ribbons along closed loops around a central sing

248 uid crystals, one-dimensional supramolecular twisted ribbons and two-dimensional colloidal membranes.

249 the formation of many-turn Mobius strips or twisted ribbons when the topological charge of one of th

250 o enables robust assembly of one-dimensional twisted ribbons, which behave as effective supramolecula

251 e a synthetic phenotype consisting of short, twisted roots with disordered cortical microtubule array

252 esses three aromatic rings and these adopt a twisted "S"-shaped conformation when bound to A. thalian

253 population and that Skp2 inhibition reverts Twist's effects on CSC regulation.

254 wisting is concentration dependent, and (ii) twisting saturates at elevated concentrations.

255 and characterization of two allelic mutants, twisted seed1-1 (tws1-1) and tws1-2, which exhibit an ar

256 However, in an intriguing twist, some microalgal species can use pseudocobalamin i

257 used to increase the modulus and strength of twist-spun carbon nanotube yarns by up to 12-fold and 2.

258 This twist stability enables torsional artificial-muscle moto

259 ogether, this study uncovering Skp2-mediated Twist stabilization and oncogenic functions in CRPC offe

260 crobial Fe(II) oxidation and, in addition, a twisted stalk structure obtained from an environmental b

261 a circulating magnetization structure and a twisted state that appears to correspond to an 'anti-Blo

262 ical condition that mimicked the early-onset twisting, stiff limbs and tremor that is observed in dys

263 ts more open structure, whereas the opposite twist-stretch coupling of both molecules is due to the v

264 ng constant obtained for dsRNA, the opposite twist-stretch coupling, and its nontrivial force depende

265 and demonstrate that bending, in addition to twist-stretch motions, underpin the sub-mus dynamics of

266 disilene 2 featuring a highly trans-bent and twisted structure and the longest silicon-silicon double

267 anti-addition pathway was favored due to the twisted structure of 2.

268 art of the second hyperpolarizability in the twisted structures is much greater than the imaginary pa

269 we report on the observation of small angle twist sub-grain boundaries in a typical MAX phase Ti3AlC

270 Twisted system: A photochemical cyclodehydrochlorination

271 otropic cylindrical bundles and anisotropic, twisted-tape bundles.

272 PNA has a much lower helical twist than RNA and the resulting duplex has an intermedi

273 pt area reveals that the rope's core is more twisted than its average of four turns.

274 (II) and, via intermolecular ionic contacts, twist the ligand's pyridine rings into a left-handed (M)

275 , and the binding of IkappaBalpha appears to twist the NFkappaB heterodimer so that the DNA can no lo

276 Scannevin and colleagues now elegantly twist the plot and achieve ultimate selectivity: They ta

277 f high-energy particle physics, and they can twist the quantum phase of electrons into topologically

278 to the cytoplasm, contacts the C-linker, and twists the inner helical gate shut.

279 witch regions may work with the inter-domain twist to initiate and direct arrestin-mediated signaling

280 This adds a new twist to the traditional view about binocular processing

281 recent genetic studies have added unexpected twists to this mechanism: certain NCR peptides are essen

282 The beta-catenin-Snail1-Twist transcription factor cluster is up-regulated and n

283 Twist transcription factors, members of the basic helix-

284 raphy and computed tomography as part of the TWIST (Tweesteden Mild Stenosis) study.

285 Twisted two-dimensional aromatic frameworks have been pr

286 RNF8-promoted Twist ubiquitination is required for Twist localization

287 the ArF-ArH interactions, and the resulting twisted, unaggregated chromophores, occur in these solid

288 Polymer springs that twist under irradiation with light, in a manner that mim

289 th changes in global longitudinal strain, LV twisting-untwisting (P<0.05).

290 ensed pi-systems, with lower energy gaps for twisted versus untwisted systems.

291 he push-pull character of the electron donor twisted viologen structure, which helps formation of the

292 In zebrafish, twist was expressed in early embryonic vasculature where

293 le basal rotation was increased in males, LV twist was not significantly different between the sexes

294 Twisting was controlled using ethidium bromide or SYBR G

295 d Snail1 expression, and to lesser extent of Twist, was related to airflow obstruction and to express

296 findings demonstrate that DNA nanorails: (i) twist when subjected to intercalators and the amount of

297 onfiguration typically induced a PMP helical twist, while an S configuration induced a MPM helical tw

298 ments progressively unwind from their native twist with increasing surface interaction and surface cu

299 eveals two types of NCT motions, bending and twisting, with respect to PS1.

300 residue influences the left- or right-handed twist without changing the pitch of the formed helix.